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833 results on '"Schmidt, Henning"'

302. DESIREE as a new tool for interstellar ion chemistry

Author

Schmidt, Henning T., primary, Johansson, Henrik A.B., additional, Thomas, Richard D., additional, Geppert, Wolf D., additional, Haag, Nicole, additional, Reinhed, Peter, additional, Rosén, Stefan, additional, Larsson, Mats, additional, Danared, Håkan, additional, Rensfelt, K.-G., additional, Liljeby, Leif, additional, Bagge, Lars, additional, Björkhage, Mikael, additional, Blom, Mikael, additional, Löfgren, Patrik, additional, Källberg, Anders, additional, Simonsson, Ansgar, additional, Paál, Andras, additional, Zettergren, Henning, additional, and Cederquist, Henrik, additional

Published
2008
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328. HapticWalker – Haptic foot device for gait rehabilitation.

Author

Schmidt, Henning, Krüger, Jörg, and Hesse, Stefan

Abstract

The restoration of gait for patients with impairments of the central nervous system (CNS), like, e.g., stroke, spinal cord injury (SCI) and traumatic brain injury (TBI) is an integral part of rehabilitation. The rehabilitation of CNS impairments usually takes several months at minimum and its outcome often influences whether a patient can return home or to work. Particularly stroke is the leading cause for disability in all industrialised countries; the incidence is approximately one million patients in the European Union each year [1, 2]. Modern concepts of motor learning favour a task specific training, i.e., to relearn walking, the patient should ideally train all walking movements, needed in daily life, repetitively in a physically correct manner [3]. Conventional training methods based on this approach proved to be effective, e.g., treadmill training [4], but they require great physical effort from the physiotherapists to assist the patient – so does even more training of free walking guided by at least two physiotherapists. [ABSTRACT FROM AUTHOR]

Published
2008
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333. The Aarhus warm EBIS storage ring injection program.

Author

Pedersen, Ulrik V., Hertel, Niels, Hvelplund, Preben, Mo\ller, So\ren P., Liljeby, Leif, Schmidt, Henning T., and Yu, Dehong

Subjects
ION sources, NUCLEAR physics instruments, ELECTRON beams
Abstract

A warm electron beam ion source (EBIS) for the production of multiply charged ions for injection into the heavy-ion storage ring ASTRID (Arhus STorage RIng Denmark) at the Institute of Physics and Astronomy, University of Aarhus, has now become operational. The aim is to produce moderately charged ions in amounts which match the requirements of ASTRID. For elements lighter than oxygen, ions of all charge states can be produced with sufficient intensity for injection. The same is true for heavier ions with charge states up to ∼ 15. [ABSTRACT FROM AUTHOR]

Published
2001

341. Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination

Author

Muris, Daan F.R., primary, Bezzubova, Olga, additional, Buerstedde, Jean-Marie, additional, Vreeken, Kees, additional, Balajee, A.S., additional, Osgood, Chris J., additional, Troelstra, Christine, additional, Hoeijmakers, Jan H.J., additional, Ostermann, Kai, additional, Schmidt, Henning, additional, Natarajan, A.T., additional, Eeken, Jan C.J., additional, Lohman, Paul H.M., additional, and Pastink, Albert, additional

Published
1994
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345. The sirtuin SIRT6 regulates stress granule formation in C. elegans and mammals.

Author

Jedrusik-Bode, Monika, Studencka, Maja, Smolka, Christian, Baumann, Tobias, Schmidt, Henning, Kampf, Jan, Paap, Franziska, Martin, Sophie, Tazi, Jamal, Müller, Kristian M., Krüger, Marcus, Braun, Thomas, and Bober, Eva

Subjects
MAMMALIAN cell cycle, STRESS granules, MAMMALS, SIRTUINS, CELLS
Abstract

SIRT6 is a NAD+-dependent deacetylase that modulates chromatin structure and safeguards genomic stability. Until now, SIRT6 has been assigned to the nucleus and only nuclear targets of SIRT6 are known. Here, we demonstrate that in response to stress, C. elegans SIR-2.4 and its mammalian orthologue SIRT6 localize to cytoplasmic stress granules, interact with various stress granule components and induce their assembly. Loss of SIRT6 or inhibition of its catalytic activity in mouse embryonic fibroblasts impairs stress granule formation and delays disassembly during recovery, whereas deficiency of SIR-2.4 diminishes maintenance of P granules and decreases survival of C. elegans under stress conditions. Our findings uncover a novel, evolutionary conserved function of SIRT6 in the maintenance of stress granules in response to stress. [ABSTRACT FROM AUTHOR]

Published
2013
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