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301. Feinstaubexposition und subklinische Inflammation in der Lunge: Ergebnisse aus der SALIA-Kohorten-Studie

Author

Vossoughi, Mohammad, Schikowski, Tamara, Vierkötter, Andrea, Sugiri, Dorothea, Raulf-Heimsoth, Monika, Casjens, Swaantje, Brüning, Thomas Klaus, and Krämer, Ursula

Subjects
Lungenfunktion, Inflammationsmarker im Sputum, ddc: 610, Luftverschmutzung, 610 Medical sciences, Medicine, Feinstaubexposition, Subklinische Inflammation
Abstract

Einleitung: Eine Induktion von Entzündungsprozessen gilt als einer der wichtigsten Mechanismen, die möglicherweise die Wirkung einer Partikelexposition auf die Gesundheit erklären können. Mit den Daten der SALIA-Studie, einer Kohortenstudie an älteren Frauen aus dem Ruhrgebiet,[for full text, please go to the a.m. URL], GMDS 2012; 57. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie e.V. (GMDS)

Published
2012

302. Association of air pollution with cognitive functions and its modification by APOE gene variants in elderly women

Author

Schikowski, Tamara, primary, Vossoughi, Mohammad, additional, Vierkötter, Andrea, additional, Schulte, Thomas, additional, Teichert, Tom, additional, Sugiri, Dorothee, additional, Fehsel, Karin, additional, Tzivian, Lilian, additional, Bae, Il-seok, additional, Ranft, Ulrich, additional, Hoffmann, Barbara, additional, Probst-Hensch, Nicole, additional, Herder, Christian, additional, Krämer, Ursula, additional, and Luckhaus, Christian, additional

Published
2015
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303. Long-Term Exposure To Air Pollution And Traffic Noise And Global Cognitive Score – Results From The Heinz Nixdorf-Recall Study

Author

Tzivian, Lilian, primary, Dlugaj, Martha, additional, Winkler, Angela, additional, Hennig, Frauke, additional, Fuks, Kateryna, additional, Vossoughi, Mohammad, additional, Schikowski, Tamara, additional, Erbel, Raimund, additional, Jöckel, Karl-Heinz, additional, Moebus, Susanne, additional, Hoffmann, Barbara, additional, and Weimar, Christian, additional

Published
2015
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304. Epidemiological evidence that indoor air pollution from cooking with solid fuels accelerates skin aging in Chinese women

Author

Li, Miaozhu, primary, Vierkötter, Andrea, additional, Schikowski, Tamara, additional, Hüls, Anke, additional, Ding, Anan, additional, Matsui, Mary S., additional, Deng, Binwei, additional, Ma, Chuan, additional, Ren, Aiguo, additional, Zhang, Juan, additional, Tan, Jingze, additional, Yang, Yajun, additional, Jin, Li, additional, Krutmann, Jean, additional, Li, Zhiwen, additional, and Wang, Sijia, additional

Published
2015
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305. Gender differences in adult-onset asthma: results from the Swiss SAPALDIA cohort study

Author

Hansen, Sofie, primary, Probst-Hensch, Nicole, additional, Keidel, Dirk, additional, Dratva, Julia, additional, Bettschart, Robert, additional, Pons, Marco, additional, Burdet, Luc, additional, Bridevaux, Pierre-Olivier, additional, Schikowski, Tamara, additional, Schindler, Christian, additional, Rochat, Thierry, additional, and Zemp, Elisabeth, additional

Published
2015
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306. Ambient Air Pollution and Adult Asthma Incidence in Six European Cohorts (ESCAPE)

Author

Jacquemin, Bénédicte, primary, Siroux, Valérie, additional, Sanchez, Margaux, additional, Carsin, Anne-Elie, additional, Schikowski, Tamara, additional, Adam, Martin, additional, Bellisario, Valeria, additional, Buschka, Anna, additional, Bono, Roberto, additional, Brunekreef, Bert, additional, Cai, Yutong, additional, Cirach, Marta, additional, Clavel-Chapelon, Françoise, additional, Declercq, Christophe, additional, de Marco, Roberto, additional, de Nazelle, Audrey, additional, Ducret-Stich, Regina E., additional, Ferretti, Virginia Valeria, additional, Gerbase, Margaret W., additional, Hardy, Rebecca, additional, Heinrich, Joachim, additional, Janson, Christer, additional, Jarvis, Deborah, additional, Al Kanaani, Zaina, additional, Keidel, Dirk, additional, Kuh, Diana, additional, Le Moual, Nicole, additional, Nieuwenhuijsen, Mark J., additional, Marcon, Alessandro, additional, Modig, Lars, additional, Pin, Isabelle, additional, Rochat, Thierry, additional, Schindler, Christian, additional, Sugiri, Dorothea, additional, Stempfelet, Morgane, additional, Temam, Sofia, additional, Tsai, Ming-Yi, additional, Varraso, Raphaëlle, additional, Vienneau, Danielle, additional, Vierkötter, Andrea, additional, Hansell, Anna L., additional, Krämer, Ursula, additional, Probst-Hensch, Nicole M., additional, Sunyer, Jordi, additional, Künzli, Nino, additional, and Kauffmann, Francine, additional

Published
2015
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307. Association between Advanced Glycation End Products and Impaired Fasting Glucose: Results from the SALIA Study

Author

Teichert, Tom, primary, Hellwig, Anne, additional, Peßler, Annette, additional, Hellwig, Michael, additional, Vossoughi, Mohammad, additional, Sugiri, Dorothea, additional, Vierkötter, Andrea, additional, Schulte, Thomas, additional, Freund, Juliane, additional, Roden, Michael, additional, Hoffmann, Barbara, additional, Schikowski, Tamara, additional, Luckhaus, Christian, additional, Krämer, Ursula, additional, Henle, Thomas, additional, and Herder, Christian, additional

Published
2015
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311. Effects of long-term exposure to air pollution on natural-cause mortality : an analysis of 22 European cohorts within the multicentre ESCAPE project

Author

Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W, Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L, Ostenson, Claes-Göran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Göran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Krämer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Künzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Françoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, Hoek, Gerard, Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W, Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L, Ostenson, Claes-Göran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Göran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Krämer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Künzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Françoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, and Hoek, Gerard

Abstract

BACKGROUND: Few studies on long-term exposure to air pollution and mortality have been reported from Europe. Within the multicentre European Study of Cohorts for Air Pollution Effects (ESCAPE), we aimed to investigate the association between natural-cause mortality and long-term exposure to several air pollutants. METHODS: We used data from 22 European cohort studies, which created a total study population of 367 251 participants. All cohorts were general population samples, although some were restricted to one sex only. With a strictly standardised protocol, we assessed residential exposure to air pollutants as annual average concentrations of particulate matter (PM) with diameters of less than 2·5 μm (PM2·5), less than 10 μm (PM10), and between 10 μm and 2·5 μm (PMcoarse), PM2.5 absorbance, and annual average concentrations of nitrogen oxides (NO2 and NOx), with land use regression models. We also investigated two traffic intensity variables-traffic intensity on the nearest road (vehicles per day) and total traffic load on all major roads within a 100 m buffer. We did cohort-specific statistical analyses using confounder models with increasing adjustment for confounder variables, and Cox proportional hazards models with a common protocol. We obtained pooled effect estimates through a random-effects meta-analysis. FINDINGS: The total study population consisted of 367 251 participants who contributed 5 118 039 person-years at risk (average follow-up 13·9 years), of whom 29 076 died from a natural cause during follow-up. A significantly increased hazard ratio (HR) for PM2·5 of 1·07 (95% CI 1·02-1·13) per 5 μg/m(3) was recorded. No heterogeneity was noted between individual cohort effect estimates (I(2) p value=0·95). HRs for PM2·5 remained significantly raised even when we included only participants exposed to pollutant concentrations lower than the European annual mean limit value of 25 μg/m(3) (HR 1·06, 95% CI 1·00-1·12) or below 20 μg/m(3) (1·07, 1·01-1·13). INTER

Published
2014
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312. Association of ambient air pollution with the prevalence and incidence of COPD

Author

Schikowski, Tamara, Adam, Martin, Marcon, Alessandro, Cai, Yutong, Vierkötter, Andrea, Carsin, Anne Elie, Jacquemin, Benedicte, Al Kanani, Zaina, Beelen, Rob, Birk, Matthias, Bridevaux, Pierre-Olivier, Brunekeef, Bert, Burney, Peter, Cirach, Marta, Cyrys, Josef, de Hoogh, Kees, de Marco, Roberto, de Nazelle, Audrey, Declercq, Christophe, Forsberg, Bertil, Hardy, Rebecca, Heinrich, Joachim, Hoek, Gerard, Jarvis, Debbie, Keidel, Dirk, Kuh, Diane, Kuhlbusch, Thomas, Migliore, Enrica, Mosler, Gioia, Nieuwenhuijsen, Mark J, Phuleria, Harish, Rochat, Thierry, Schindler, Christian, Villani, Simona, Tsai, Ming-Yi, Zemp, Elisabeth, Hansell, Anna, Kauffmann, Francine, Sunyer, Jordi, Probst-Hensch, Nicole, Krämer, Ursula, Künzli, Nino, Schikowski, Tamara, Adam, Martin, Marcon, Alessandro, Cai, Yutong, Vierkötter, Andrea, Carsin, Anne Elie, Jacquemin, Benedicte, Al Kanani, Zaina, Beelen, Rob, Birk, Matthias, Bridevaux, Pierre-Olivier, Brunekeef, Bert, Burney, Peter, Cirach, Marta, Cyrys, Josef, de Hoogh, Kees, de Marco, Roberto, de Nazelle, Audrey, Declercq, Christophe, Forsberg, Bertil, Hardy, Rebecca, Heinrich, Joachim, Hoek, Gerard, Jarvis, Debbie, Keidel, Dirk, Kuh, Diane, Kuhlbusch, Thomas, Migliore, Enrica, Mosler, Gioia, Nieuwenhuijsen, Mark J, Phuleria, Harish, Rochat, Thierry, Schindler, Christian, Villani, Simona, Tsai, Ming-Yi, Zemp, Elisabeth, Hansell, Anna, Kauffmann, Francine, Sunyer, Jordi, Probst-Hensch, Nicole, Krämer, Ursula, and Künzli, Nino

Abstract

The role of air pollution in chronic obstructive pulmonary disease (COPD) remains uncertain.The aim was to assess the impact of chronic exposure to air pollution on COPD in four cohorts using the standardised ESCAPE exposure estimates. Annual average particulate matter (PM), nitrogen oxides (NOx) and road traffic exposure were assigned to home addresses using land-use regression models. COPD was defined by NHANES reference equation (forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) less than the lower limit of normal) and the Global Initiative for Chronic Obstructive Lung Disease criterion (FEV1/FVC <0.70) and categorised by severity in non-asthmatics.We included 6550 subjects with assigned NOx and 3692 with PM measures. COPD was not associated with NO2 or PM10 in any individual cohort. In meta-analyses only NO2, NOx, PM10 and the traffic indicators were positively, although not significantly, associated with COPD. The only statistically significant associations were seen in females (COPD prevalence using GOLD: OR 1.57, 95% CI 1.11-2.23; and incidence: OR 1.79, 95% CI 1.21-2.68).None of the principal results were statistically significant, the weak positive associations of exposure with COPD and the significant subgroup findings need to be evaluated in further well standardised cohorts followed up for longer time, and with time-matched exposure assignments.

Published
2014
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313. Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W., Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S., Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L., Ostenson, Claes-Goeran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Goeran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H., Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Kraemer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Kuenzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Francoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, Hoek, Gerard, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W., Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S., Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L., Ostenson, Claes-Goeran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Goeran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H., Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Kraemer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Kuenzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Francoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, and Hoek, Gerard

Published
2014

314. Comparing land use regression and dispersion modelling to assess residential exposure to ambient air pollution for epidemiological studies

Author

LS IRAS EEPI ME (Milieu epidemiologie), Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, de Hoogh, Kees, Korek, Michal, Vienneau, Danielle, Keuken, Menno, Kukkonen, Jaakko, Nieuwenhuijsen, Mark J, Badaloni, Chiara, Beelen, Rob, Bolignano, Andrea, Cesaroni, Giulia, Pradas, Marta Cirach, Cyrys, Josef, Douros, John, Eeftens, Marloes, Forastiere, Francesco, Forsberg, Bertil, Fuks, Kateryna, Gehring, Ulrike, Gryparis, Alexandros, Gulliver, John, Hansell, Anna L, Hoffmann, Barbara, Johansson, Christer, Jonkers, Sander, Kangas, Leena, Katsouyanni, Klea, Künzli, Nino, Lanki, Timo, Memmesheimer, Michael, Moussiopoulos, Nicolas, Modig, Lars, Pershagen, Göran, Probst-Hensch, Nicole, Schindler, Christian, Schikowski, Tamara, Sugiri, Dorothee, Teixidó, Oriol, Tsai, Ming-Yi, Yli-Tuomi, Tarja, Brunekreef, Bert, Hoek, Gerard, Bellander, Tom, LS IRAS EEPI ME (Milieu epidemiologie), Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, de Hoogh, Kees, Korek, Michal, Vienneau, Danielle, Keuken, Menno, Kukkonen, Jaakko, Nieuwenhuijsen, Mark J, Badaloni, Chiara, Beelen, Rob, Bolignano, Andrea, Cesaroni, Giulia, Pradas, Marta Cirach, Cyrys, Josef, Douros, John, Eeftens, Marloes, Forastiere, Francesco, Forsberg, Bertil, Fuks, Kateryna, Gehring, Ulrike, Gryparis, Alexandros, Gulliver, John, Hansell, Anna L, Hoffmann, Barbara, Johansson, Christer, Jonkers, Sander, Kangas, Leena, Katsouyanni, Klea, Künzli, Nino, Lanki, Timo, Memmesheimer, Michael, Moussiopoulos, Nicolas, Modig, Lars, Pershagen, Göran, Probst-Hensch, Nicole, Schindler, Christian, Schikowski, Tamara, Sugiri, Dorothee, Teixidó, Oriol, Tsai, Ming-Yi, Yli-Tuomi, Tarja, Brunekreef, Bert, Hoek, Gerard, and Bellander, Tom

Published
2014

315. Cross-sectional associations between air pollution and chronic bronchitis: an ESCAPE meta-analysis across five cohorts

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Cai, Yutong, Schikowski, Tamara, Adam, Martin, Buschka, Anna, Carsin, Anne-Elie, Jacquemin, Benedicte, Marcon, Alessandro, Sanchez, Margaux, Vierkoetter, Andrea, Al-Kanaani, Zaina, Beelen, Rob, Birk, Matthias, Brunekreef, Bert, Cirach, Marta, Clavel-Chapelon, Franoise, Declercq, Christophe, de Hoogh, Kees, de Nazelle, Audrey, Ducret-Stich, Regina E., Ferretti, Virginia Valeria, Forsberg, Bertil, Gerbase, Margaret W., Hardy, Rebecca, Heinrich, Joachim, Hoek, Gerard, Jarvis, Debbie, Keidel, Dirk, Kuh, Diana, Nieuwenhuijsen, Mark J., Ragettli, Martina S., Ranzi, Andrea, Rochat, Thierry, Schindler, Christian, Sugiri, Dorothea, Temam, Sofia, Tsai, Ming-Yi, Varraso, Raphaelle, Kauffmann, Francine, Kraemer, Ursula, Sunyer, Jordi, Kuenzli, Nino, Probst-Hensch, Nicole, Hansell, Anna L., Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Cai, Yutong, Schikowski, Tamara, Adam, Martin, Buschka, Anna, Carsin, Anne-Elie, Jacquemin, Benedicte, Marcon, Alessandro, Sanchez, Margaux, Vierkoetter, Andrea, Al-Kanaani, Zaina, Beelen, Rob, Birk, Matthias, Brunekreef, Bert, Cirach, Marta, Clavel-Chapelon, Franoise, Declercq, Christophe, de Hoogh, Kees, de Nazelle, Audrey, Ducret-Stich, Regina E., Ferretti, Virginia Valeria, Forsberg, Bertil, Gerbase, Margaret W., Hardy, Rebecca, Heinrich, Joachim, Hoek, Gerard, Jarvis, Debbie, Keidel, Dirk, Kuh, Diana, Nieuwenhuijsen, Mark J., Ragettli, Martina S., Ranzi, Andrea, Rochat, Thierry, Schindler, Christian, Sugiri, Dorothea, Temam, Sofia, Tsai, Ming-Yi, Varraso, Raphaelle, Kauffmann, Francine, Kraemer, Ursula, Sunyer, Jordi, Kuenzli, Nino, Probst-Hensch, Nicole, and Hansell, Anna L.

Published
2014

316. Arterial Blood Pressure and Long-Term Exposure to Traffic-Related Air Pollution: An Analysis in the European Study of Cohorts for Air Pollution Effects (ESCAPE)

Author

Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Fuks, Kateryna B., Weinmayr, Gudrun, Foraster, Maria, Dratva, Julia, Hampel, Regina, Houthuijs, Danny, Oftedal, Bente, Oudin, Anna, Panasevich, Sviatlana, Penell, Johanna, Sommar, Johan N., Sorensen, Mette, Tiittanen, Pekka, Wolf, Kathrin, Xun, Wei W., Aguilera, Inmaculada, Basagana, Xavier, Beelen, Rob, Bots, Michiel L., Brunekreef, Bert, Bueno-de-Mesquita, H. Bas, Caracciolo, Barbara, Cirach, Marta, de Faire, Ulf, de Nazelle, Audrey, Eeftens, Marloes, Elosua, Roberto, Erbel, Raimund, Forsberg, Bertil, Fratiglioni, Laura, Gaspoz, Jean-Michel, Hilding, Agneta, Jula, Antti, Korek, Michal, Kraemer, Ursula, Kuenzli, Nino, Lanki, Timo, Leander, Karin, Magnusson, Patrik K. E., Marrugat, Jaume, Nieuwenhuijsen, Mark J., Oestenson, Claes-Goeran, Pedersen, Nancy L., Pershagen, Goeran, Phuleria, Harish C., Probst-Hensch, Nicole M., Raaschou-Nielsen, Ole, Schaffner, Emmanuel, Schikowski, Tamara, Schindler, Christian, Schwarze, Per E., Sogaard, Anne J., Sugiri, Dorothea, Swart, Wim J. R., Tsai, Ming-Yi, Turunen, Anu W., Vineis, Paolo, Peters, Annette, Hoffmann, Barbara, Dep IRAS, LS IRAS EEPI ME (Milieu epidemiologie), Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, Fuks, Kateryna B., Weinmayr, Gudrun, Foraster, Maria, Dratva, Julia, Hampel, Regina, Houthuijs, Danny, Oftedal, Bente, Oudin, Anna, Panasevich, Sviatlana, Penell, Johanna, Sommar, Johan N., Sorensen, Mette, Tiittanen, Pekka, Wolf, Kathrin, Xun, Wei W., Aguilera, Inmaculada, Basagana, Xavier, Beelen, Rob, Bots, Michiel L., Brunekreef, Bert, Bueno-de-Mesquita, H. Bas, Caracciolo, Barbara, Cirach, Marta, de Faire, Ulf, de Nazelle, Audrey, Eeftens, Marloes, Elosua, Roberto, Erbel, Raimund, Forsberg, Bertil, Fratiglioni, Laura, Gaspoz, Jean-Michel, Hilding, Agneta, Jula, Antti, Korek, Michal, Kraemer, Ursula, Kuenzli, Nino, Lanki, Timo, Leander, Karin, Magnusson, Patrik K. E., Marrugat, Jaume, Nieuwenhuijsen, Mark J., Oestenson, Claes-Goeran, Pedersen, Nancy L., Pershagen, Goeran, Phuleria, Harish C., Probst-Hensch, Nicole M., Raaschou-Nielsen, Ole, Schaffner, Emmanuel, Schikowski, Tamara, Schindler, Christian, Schwarze, Per E., Sogaard, Anne J., Sugiri, Dorothea, Swart, Wim J. R., Tsai, Ming-Yi, Turunen, Anu W., Vineis, Paolo, Peters, Annette, and Hoffmann, Barbara

Published
2014

317. Association of ambient air pollution with the prevalence and incidence of COPD

Author

LS IRAS EEPI ME (Milieu epidemiologie), Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Schikowski, Tamara, Adam, Martin, Marcon, Alessandro, Cai, Yutong, Vierkötter, Andrea, Carsin, Anne Elie, Jacquemin, Benedicte, Al Kanani, Zaina, Beelen, Rob, Birk, Matthias, Bridevaux, Pierre Olivier, Brunekreef, Bert, Burney, Peter, Cirach, Marta, Cyrys, Josef, De Hoogh, Kees, De Marco, Roberto, De Nazelle, Audrey, Declercq, Christophe, Forsberg, Bertil, Hardy, Rebecca, Heinrich, Joachim, Hoek, Gerard, Jarvis, Debbie, Keidel, Dirk, Kuh, Diane, Kuhlbusch, Thomas, Migliore, Enrica, Mosler, Gioia, Nieuwenhuijsen, Mark J., Phuleria, Harish, Rochat, Thierry, Schindler, Christian, Villani, Simona, Tsai, Ming Yi, Zemp, Elisabeth, Hansell, Anna, Kauffmann, Francine, Sunyer, Jordi, Probst-Hensch, Nicole, Krämer, Ursula, Künzli, Nino, LS IRAS EEPI ME (Milieu epidemiologie), Dep IRAS, Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA2, IRAS RATIA-SIB, Schikowski, Tamara, Adam, Martin, Marcon, Alessandro, Cai, Yutong, Vierkötter, Andrea, Carsin, Anne Elie, Jacquemin, Benedicte, Al Kanani, Zaina, Beelen, Rob, Birk, Matthias, Bridevaux, Pierre Olivier, Brunekreef, Bert, Burney, Peter, Cirach, Marta, Cyrys, Josef, De Hoogh, Kees, De Marco, Roberto, De Nazelle, Audrey, Declercq, Christophe, Forsberg, Bertil, Hardy, Rebecca, Heinrich, Joachim, Hoek, Gerard, Jarvis, Debbie, Keidel, Dirk, Kuh, Diane, Kuhlbusch, Thomas, Migliore, Enrica, Mosler, Gioia, Nieuwenhuijsen, Mark J., Phuleria, Harish, Rochat, Thierry, Schindler, Christian, Villani, Simona, Tsai, Ming Yi, Zemp, Elisabeth, Hansell, Anna, Kauffmann, Francine, Sunyer, Jordi, Probst-Hensch, Nicole, Krämer, Ursula, and Künzli, Nino

Published
2014

319. Exposure to residential green and blue space and the natural environment is associated with a lower incidence of psychiatric disorders in middle-aged and older adults: findings from the UK Biobank.

Author

Liu, Bao-Peng, Huxley, Rachel R., Schikowski, Tamara, Hu, Ke-Jia, Zhao, Qi, and Jia, Cun-Xian

Subjects
*MIDDLE-aged persons, *MENTAL illness, *OLDER people, *SPACE environment, *PROPORTIONAL hazards models, *ADJUSTMENT disorders, *PERSONAL space, *VASCULAR dementia
Abstract

Background: There is increasing evidence for the role of environmental factors and exposure to the natural environment on a wide range of health outcomes. Whether exposure to green space, blue space, and the natural environment (GBN) is associated with risk of psychiatric disorders in middle-aged and older adults has not been prospectively examined. Methods: Longitudinal data from the UK biobank was used. At the study baseline (2006–2010), 363,047 participants (women: 53.4%; mean age 56.7 ± 8.1 years) who had not been previously diagnosed with any psychiatric disorder were included. Follow-up was achieved by collecting records from hospitals and death registers. Measurements of green and blue space modeled from land use data and natural environment from Land Cover Map were assigned to the residential address for each participant. Cox proportional hazard models with adjustment for potential confounders were used to explore the longitudinal associations between GBN and any psychiatric disorder and then by specific psychiatric disorders (dementia, substance abuse, psychotic disorder, depression, and anxiety) in middle-aged and older adults. Results: During an average follow-up of 11.5 ± 2.8 years, 49,865 individuals were diagnosed with psychiatric disorders. Compared with the first tertile (lowest) of exposure, blue space at 300 m buffer [hazard ratio (HR): 0.973, 95% confidence interval (CI): 0.952–0.994] and natural environment at 300 m buffer (HR: 0.970, 95% CI: 0.948–0.992) and at 1000 m buffer (HR: 0.975, 95% CI: 0.952–0.999) in the third tertile (highest) were significantly associated with lower risk of incident psychiatric disorders, respectively. The risk of incident dementia was statistically decreased when exposed to the third tertile (highest) of green space and natural environment at 1000 m buffer. The third tertile (highest) of green space at 300 m and 1000 m buffer and natural environment at 300 m and 1000 m buffer was associated with a reduction of 30.0%, 31.8%, 21.7%, and 30.3% in the risk of developing a psychotic disorder, respectively. Subgroup analysis suggested that the elderly, men, and those living with some comorbid conditions may derive greater benefits associated with exposure to GBN. Conclusions: This study suggests that GBN has significant benefits for lowering the risk of psychiatric disorders in middle-aged and older adults. Future studies are warranted to validate these findings and to understand the potential mechanistic pathways underpinning these novel findings. [ABSTRACT FROM AUTHOR]

Published
2024
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320. Gene-environment interaction in the association of residential greenness and 25(OH) vitamin D.

Author

Thiering, Elisabeth, Markevych, Iana, Kress, Sara, Astell-Burt, Thomas, Feng, Xiaoqi, Altug, Hicran, Koletzko, Sibylle, Bauer, Carl-Peter, von Berg, Andrea, Berdel, Dietrich, Herberth, Gunda, Schikowski, Tamara, Heinrich, Joachim, and Standl, Marie

Subjects
GENOTYPE-environment interaction, NORMALIZED difference vegetation index, PHYSICAL activity, VITAMINS, VITAMIN D
Abstract

There is increasing awareness for beneficial health effects of green space surrounding the home, but the underlying mechanisms are not yet fully understood and challenging to study given the correlation with other exposures. Here, the association of residential greenness and vitamin D including a gene-environment interaction is investigated. 25-hydroxyvitamin D (25(OH)D) was measured by electrochemiluminescence at ages 10 and 15 years in participants of two German birth cohorts GINIplus and LISA. Greenness was measured using the Landsat-derived Normalized Difference Vegetation Index (NDVI) in a 500 m buffer surrounding the home. Linear and logistic regression models were applied at both time points adjusted for several covariates (N 10Y = 2,504, N 15Y = 2,613). In additional analyses vitamin D-related genes, physical activity, time spent outdoors, supplements, and measurement season were investigated as potential confounders or effect modifiers. A 1.5-SD increase in NDVI was significantly associated with increased 25(OH)D values at ages 10 and 15 years (β 10y = 2.41 nmol/l, p=<0.01; β 15y = 2.03 nmol/l, p = 0.02). In stratified analyses, the associations were not seen in participants spending more than 5 h/day outside in summer, having a high physical activity level, taking supplements, or being examined during the winter season. In a subset (n = 1,732) with genetic data, a significant gene-environment interaction of NDVI with CYP2R1 , an upstream gene in 25(OH)D synthesis, was observed at age 10 years. When investigating 25(OH)D sufficiency, defined as values above 50 nmol/l, a 1.5-SD increase in NDVI was associated with significantly higher odds of having sufficient 25 (OH)D levels at age 10 years (OR = 1.48, 1.19–1.83). In conclusion, robust associations between residential greenness and 25 (OH)D levels were observed in children and adolescents independent of other confounders and additionally supported by the presence of a gene-environment interaction. Effects of NDVI were stronger in those having lower vitamin D levels at age 10 years due to their covariate profile or genetically lower 25(OH)D synthesis. [Display omitted] • NDVI is robustly associated with 25(OH)D in children and adolescents. • Gene × Environment interaction present for CYP2R1. • Sub-group analyses reveal differences depending on covariate profile. [ABSTRACT FROM AUTHOR]

Published
2023
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322. Long-Term Air Pollution Exposure and Diabetes in a Population-Based Swiss Cohort

Author

Eze*, Ikenna, primary, Schaffner, Emmanuel, additional, Fischer, Evelyn, additional, Schikowski, Tamara, additional, Adam, Martin, additional, Imboden, Medea, additional, Tsai, Ming, additional, Carballo, David, additional, Eckardstein, Arnold von, additional, Künzli, Nino, additional, Schindler, Christian, additional, and Probst-Hensch, Nicole, additional

Published
2014
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324. Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis

Author

Adam, Martin, primary, Schikowski, Tamara, additional, Carsin, Anne Elie, additional, Cai, Yutong, additional, Jacquemin, Benedicte, additional, Sanchez, Margaux, additional, Vierkötter, Andrea, additional, Marcon, Alessandro, additional, Keidel, Dirk, additional, Sugiri, Dorothee, additional, Al Kanani, Zaina, additional, Nadif, Rachel, additional, Siroux, Valérie, additional, Hardy, Rebecca, additional, Kuh, Diana, additional, Rochat, Thierry, additional, Bridevaux, Pierre-Olivier, additional, Eeftens, Marloes, additional, Tsai, Ming-Yi, additional, Villani, Simona, additional, Phuleria, Harish Chandra, additional, Birk, Matthias, additional, Cyrys, Josef, additional, Cirach, Marta, additional, de Nazelle, Audrey, additional, Nieuwenhuijsen, Mark J., additional, Forsberg, Bertil, additional, de Hoogh, Kees, additional, Declerq, Christophe, additional, Bono, Roberto, additional, Piccioni, Pavilio, additional, Quass, Ulrich, additional, Heinrich, Joachim, additional, Jarvis, Deborah, additional, Pin, Isabelle, additional, Beelen, Rob, additional, Hoek, Gerard, additional, Brunekreef, Bert, additional, Schindler, Christian, additional, Sunyer, Jordi, additional, Krämer, Ursula, additional, Kauffmann, Francine, additional, Hansell, Anna L., additional, Künzli, Nino, additional, and Probst-Hensch, Nicole, additional

Published
2014
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325. Long-term air pollution exposure and diabetes in a population-based Swiss cohort

Author

Eze, Ikenna C., primary, Schaffner, Emmanuel, additional, Fischer, Evelyn, additional, Schikowski, Tamara, additional, Adam, Martin, additional, Imboden, Medea, additional, Tsai, Ming, additional, Carballo, David, additional, von Eckardstein, Arnold, additional, Künzli, Nino, additional, Schindler, Christian, additional, and Probst-Hensch, Nicole, additional

Published
2014
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326. Air pollution and subclinical airway inflammation in the SALIA cohort study

Author

Vossoughi, Mohammad, primary, Schikowski, Tamara, additional, Vierkötter, Andrea, additional, Sugiri, Dorothea, additional, Hoffmann, Barbara, additional, Teichert, Tom, additional, Herder, Christian, additional, Schulte, Thomas, additional, Luckhaus, Christian, additional, Raulf-Heimsoth, Monika, additional, Casjens, Swaantje, additional, Brüning, Thomas, additional, and Krämer, Ursula, additional

Published
2014
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327. Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project

Author

Beelen, Rob, primary, Raaschou-Nielsen, Ole, additional, Stafoggia, Massimo, additional, Andersen, Zorana Jovanovic, additional, Weinmayr, Gudrun, additional, Hoffmann, Barbara, additional, Wolf, Kathrin, additional, Samoli, Evangelia, additional, Fischer, Paul, additional, Nieuwenhuijsen, Mark, additional, Vineis, Paolo, additional, Xun, Wei W, additional, Katsouyanni, Klea, additional, Dimakopoulou, Konstantina, additional, Oudin, Anna, additional, Forsberg, Bertil, additional, Modig, Lars, additional, Havulinna, Aki S, additional, Lanki, Timo, additional, Turunen, Anu, additional, Oftedal, Bente, additional, Nystad, Wenche, additional, Nafstad, Per, additional, De Faire, Ulf, additional, Pedersen, Nancy L, additional, Östenson, Claes-Göran, additional, Fratiglioni, Laura, additional, Penell, Johanna, additional, Korek, Michal, additional, Pershagen, Göran, additional, Eriksen, Kirsten Thorup, additional, Overvad, Kim, additional, Ellermann, Thomas, additional, Eeftens, Marloes, additional, Peeters, Petra H, additional, Meliefste, Kees, additional, Wang, Meng, additional, Bueno-de-Mesquita, Bas, additional, Sugiri, Dorothea, additional, Krämer, Ursula, additional, Heinrich, Joachim, additional, de Hoogh, Kees, additional, Key, Timothy, additional, Peters, Annette, additional, Hampel, Regina, additional, Concin, Hans, additional, Nagel, Gabriele, additional, Ineichen, Alex, additional, Schaffner, Emmanuel, additional, Probst-Hensch, Nicole, additional, Künzli, Nino, additional, Schindler, Christian, additional, Schikowski, Tamara, additional, Adam, Martin, additional, Phuleria, Harish, additional, Vilier, Alice, additional, Clavel-Chapelon, Françoise, additional, Declercq, Christophe, additional, Grioni, Sara, additional, Krogh, Vittorio, additional, Tsai, Ming-Yi, additional, Ricceri, Fulvio, additional, Sacerdote, Carlotta, additional, Galassi, Claudia, additional, Migliore, Enrica, additional, Ranzi, Andrea, additional, Cesaroni, Giulia, additional, Badaloni, Chiara, additional, Forastiere, Francesco, additional, Tamayo, Ibon, additional, Amiano, Pilar, additional, Dorronsoro, Miren, additional, Katsoulis, Michail, additional, Trichopoulou, Antonia, additional, Brunekreef, Bert, additional, and Hoek, Gerard, additional

Published
2014
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328. Development of NO2 and NOx land use regression models for estimating air pollution exposure in 36 study areas in Europe : the ESCAPE project

Author

Beelen, Rob, Hoek, Gerard, Vienneau, Danielle, Eeftens, Marloes, Dimakopoulou, Konstantina, Pedeli, Xanthi, Tsai, Ming-Yi, Künzli, Nino, Schikowski, Tamara, Marcon, Alessandro, Eriksen, Kirsten, Raaschou-Nielsen, Ole, Stephanou, Euripides, Evridiki, Patelarou, Lanki, Timo, Yli-Tuomi, Tarja, Declercq, Christophe, Falq, Grégoire, Stempfelet, Morgane, Birk, Matthias, Cyrys, Josef, von Klot, Stephanie, Nádor, Gizella, Varró, Mihály János, Dėdelė, Audrius, Gražulevičienė, Regina, Mölter, Anna, Lindley, Sarah, Madsen, Christian, Cesaroni, Giulia, Ranzi, Andrea, Badaloni, Chiara, Hoffmann, Barbara, Nonnemacher, Michael, Krämer, Ursula, Kuhlbusch, Thomas, Cirach, Marta, de Nazelle, Audrey, Nieuwenhuijsen, Mark, Bellander, Tom, Korek, Michal, Olsson, David, Strömgren, Magnus, Dons, Evi, Jerrett, Michael, Fischer, Paul, Brunekreef, Bert, de Hoogh, Kees, Beelen, Rob, Hoek, Gerard, Vienneau, Danielle, Eeftens, Marloes, Dimakopoulou, Konstantina, Pedeli, Xanthi, Tsai, Ming-Yi, Künzli, Nino, Schikowski, Tamara, Marcon, Alessandro, Eriksen, Kirsten, Raaschou-Nielsen, Ole, Stephanou, Euripides, Evridiki, Patelarou, Lanki, Timo, Yli-Tuomi, Tarja, Declercq, Christophe, Falq, Grégoire, Stempfelet, Morgane, Birk, Matthias, Cyrys, Josef, von Klot, Stephanie, Nádor, Gizella, Varró, Mihály János, Dėdelė, Audrius, Gražulevičienė, Regina, Mölter, Anna, Lindley, Sarah, Madsen, Christian, Cesaroni, Giulia, Ranzi, Andrea, Badaloni, Chiara, Hoffmann, Barbara, Nonnemacher, Michael, Krämer, Ursula, Kuhlbusch, Thomas, Cirach, Marta, de Nazelle, Audrey, Nieuwenhuijsen, Mark, Bellander, Tom, Korek, Michal, Olsson, David, Strömgren, Magnus, Dons, Evi, Jerrett, Michael, Fischer, Paul, Brunekreef, Bert, and de Hoogh, Kees

Abstract

Estimating within-city variability in air pollution concentrations is important. Land use regression (LUR) models are able to explain such small-scale within-city variations. Transparency in LUR model development methods is important to facilitate comparison of methods between different studies. We therefore developed LUR models in a standardized way in 36 study areas in Europe for the ESCAPE (European Study of Cohorts for Air Pollution Effects) project. Nitrogen dioxide (NO2) and nitrogen oxides (NOx) were measured with Ogawa passive samplers at 40 or 80 sites in each of the 36 study areas. The spatial variation in each area was explained by LUR modeling. Centrally and locally available Geographic Information System (GIS) variables were used as potential predictors. A leave-one out cross-validation procedure was used to evaluate the model performance. There was substantial contrast in annual average NO2 and NOx concentrations within the study areas. The model explained variances (R2) of the LUR models ranged from 55% to 92% (median 82%) for NO2 and from 49% to 91% (median 78%) for NOx. For most areas the cross-validation R2 was less than 10% lower than the model R2. Small-scale traffic and population/household density were the most common predictors. The magnitude of the explained variance depended on the contrast in measured concentrations as well as availability of GIS predictors, especially traffic intensity data were important. In an additional evaluation, models in which local traffic intensity was not offered had 10% lower R2 compared to models in the same areas in which these variables were offered. Within the ESCAPE project it was possible to develop LUR models that explained a large fraction of the spatial variance in measured annual average NO2 and NOx concentrations. These LUR models are being used to estimate outdoor concentrations at the home addresses of participants in over 30 cohort studies.

Published
2013
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329. Effects of long-term exposure to air pollution on natural-cause mortality:an analysis of 22 European cohorts within the multicentre ESCAPE project

Author

Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W, Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L, Ostenson, Claes-Göran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Göran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Krämer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Künzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Françoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, Hoek, Gerard, Beelen, Rob, Raaschou-Nielsen, Ole, Stafoggia, Massimo, Andersen, Zorana Jovanovic, Weinmayr, Gudrun, Hoffmann, Barbara, Wolf, Kathrin, Samoli, Evangelia, Fischer, Paul, Nieuwenhuijsen, Mark, Vineis, Paolo, Xun, Wei W, Katsouyanni, Klea, Dimakopoulou, Konstantina, Oudin, Anna, Forsberg, Bertil, Modig, Lars, Havulinna, Aki S, Lanki, Timo, Turunen, Anu, Oftedal, Bente, Nystad, Wenche, Nafstad, Per, De Faire, Ulf, Pedersen, Nancy L, Ostenson, Claes-Göran, Fratiglioni, Laura, Penell, Johanna, Korek, Michal, Pershagen, Göran, Eriksen, Kirsten Thorup, Overvad, Kim, Ellermann, Thomas, Eeftens, Marloes, Peeters, Petra H, Meliefste, Kees, Wang, Meng, Bueno-de-Mesquita, Bas, Sugiri, Dorothea, Krämer, Ursula, Heinrich, Joachim, de Hoogh, Kees, Key, Timothy, Peters, Annette, Hampel, Regina, Concin, Hans, Nagel, Gabriele, Ineichen, Alex, Schaffner, Emmanuel, Probst-Hensch, Nicole, Künzli, Nino, Schindler, Christian, Schikowski, Tamara, Adam, Martin, Phuleria, Harish, Vilier, Alice, Clavel-Chapelon, Françoise, Declercq, Christophe, Grioni, Sara, Krogh, Vittorio, Tsai, Ming-Yi, Ricceri, Fulvio, Sacerdote, Carlotta, Galassi, Claudia, Migliore, Enrica, Ranzi, Andrea, Cesaroni, Giulia, Badaloni, Chiara, Forastiere, Francesco, Tamayo, Ibon, Amiano, Pilar, Dorronsoro, Miren, Katsoulis, Michail, Trichopoulou, Antonia, Brunekreef, Bert, and Hoek, Gerard

Abstract

Few studies on long-term exposure to air pollution and mortality have been reported from Europe. Within the multicentre European Study of Cohorts for Air Pollution Effects (ESCAPE), we aimed to investigate the association between natural-cause mortality and long-term exposure to several air pollutants.

Published
2013

330. Occupational Exposure to Dusts, Gases, and Fumes andIncidence of Chronic Obstructive Pulmonary Disease inthe Swiss Cohort Study on Air Pollution and Lung andHeart Diseases in Adults

Author

Mehta, Amar, Miedinger, David, Keidel, Dirk, Bettschart, Robert, Bircher, Andreas, Bridevaux, Pierre-Olivier, Curjuric, Ivan, Kromhout, Hans, Probst-Hensch, Nicole, Rothe, Thomas, W. Russi, Erich, Schikowski, Tamara, Schindler, Christian, Schwartz, Joel, Vermeulen, Roel, Rochat, Thierry, Kuenzli, Nino, Mehta, Amar, Miedinger, David, Keidel, Dirk, Bettschart, Robert, Bircher, Andreas, Bridevaux, Pierre-Olivier, Curjuric, Ivan, Kromhout, Hans, Probst-Hensch, Nicole, Rothe, Thomas, W. Russi, Erich, Schikowski, Tamara, Schindler, Christian, Schwartz, Joel, Vermeulen, Roel, Rochat, Thierry, and Kuenzli, Nino

Published
2011

331. Skin aging associated with chromium among rural housewives in northern China.

Author

Na, Jigen, Li, Nan, Yan, Lailai, Schikowski, Tamara, Ye, Rongwei, Krutmann, Jean, and Li, Zhiwen

Subjects
SKIN aging, CHROMIUM, HOUSEWIVES, FERTILIZERS, TRACE elements
Abstract

Previous studies have found associations between chromium exposure and skin damage. However, few studies have focused on both chromium and skin aging. This study aimed to assess the degree of skin aging symptoms and estimate the relationship between hair chromium and skin aging among rural housewives. We recruited 405 subjects in Shanxi Province of northern China and analyzed 397 eligible hair samples with inductively coupled plasma–mass spectrometry (ICP–MS). The subjects' skin aging symptoms were assessed with SCINEXA™ (SCore of INtrinsic and EXtrinsic skin Aging). After adjusting for age and other important covariates, the regression results showed more severe skin aging symptoms in women with a higher level of hair chromium and presented an increasing linear trend. Vegetables, fruits, and beans might be a source of chromium exposure. We concluded that skin aging might be positively associated with hair chromium. It is necessary to take measures to reduce chromium exposure to prevent skin aging. • Skin aging is general but environmental factors can accelerate this process. • Chromium is a necessary trace element but toxic in excess. • Skin aging especially pigmentation may be associated with higher chromium exposure. • Chromium exposure and pigmentation have a dose-response relationship. • Plant foods may be a source of chromium exposure among women in northern China. [ABSTRACT FROM AUTHOR]

Published
2023
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341. Development of NO2 and NOx land use regression models for estimating air pollution exposure in 36 study areas in Europe – The ESCAPE project

Author

Beelen, Rob, primary, Hoek, Gerard, additional, Vienneau, Danielle, additional, Eeftens, Marloes, additional, Dimakopoulou, Konstantina, additional, Pedeli, Xanthi, additional, Tsai, Ming-Yi, additional, Künzli, Nino, additional, Schikowski, Tamara, additional, Marcon, Alessandro, additional, Eriksen, Kirsten T., additional, Raaschou-Nielsen, Ole, additional, Stephanou, Euripides, additional, Patelarou, Evridiki, additional, Lanki, Timo, additional, Yli-Tuomi, Tarja, additional, Declercq, Christophe, additional, Falq, Grégoire, additional, Stempfelet, Morgane, additional, Birk, Matthias, additional, Cyrys, Josef, additional, von Klot, Stephanie, additional, Nádor, Gizella, additional, Varró, Mihály János, additional, Dėdelė, Audrius, additional, Gražulevičienė, Regina, additional, Mölter, Anna, additional, Lindley, Sarah, additional, Madsen, Christian, additional, Cesaroni, Giulia, additional, Ranzi, Andrea, additional, Badaloni, Chiara, additional, Hoffmann, Barbara, additional, Nonnemacher, Michael, additional, Krämer, Ursula, additional, Kuhlbusch, Thomas, additional, Cirach, Marta, additional, de Nazelle, Audrey, additional, Nieuwenhuijsen, Mark, additional, Bellander, Tom, additional, Korek, Michal, additional, Olsson, David, additional, Strömgren, Magnus, additional, Dons, Evi, additional, Jerrett, Michael, additional, Fischer, Paul, additional, Wang, Meng, additional, Brunekreef, Bert, additional, and de Hoogh, Kees, additional

Published
2013
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342. S-157

Author

Künzli, Nino, primary, Schikowski, Tamara, additional, Kauffmann, Francine, additional, Hansell, Anna, additional, Krämer, Ursula, additional, Sunyer, Jordi, additional, Jacquemin, Benedicte, additional, and Probst-Hensch, Nicole, additional

Published
2012
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343. Allergy, Occupational Exposures, And Incidence Of COPD In SAPALDIA

Author

Mehta, Amar J., primary, Miedinger, David, additional, Keidel, Dirk, additional, Bettschart, Robert, additional, Bircher, Andreas, additional, Bridevaux, Pierre-Olivier, additional, Imboden, Medea, additional, Kromhout, Hans, additional, Rochat, Thierry, additional, Rothe, Thomas, additional, Russi, Erich W., additional, Schikowski, Tamara, additional, Schindler, Christian, additional, Schmid-Grendelmeier, Peter, additional, Schwartz, Joel, additional, Turk, Alexander, additional, Vermeulen, Roel, additional, Probst-Hensch, Nicole, additional, and Kuenzli, Nino, additional

Published
2012
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349. The Effect Of Body Mass Index On The Relationship Between Reduced Air Pollution And Lung Function Decline

Author

Schikowski, Tamara, primary, Schaffner, Emmanuel, additional, Phuleria, Harish, additional, Vierkoetter, Andrea, additional, Schindler, Christian, additional, Zemp, Elisabeth, additional, Liu, Sally, additional, Kraemer, Ursula, additional, Rochat, Thierry, additional, Schwartz, Joel, additional, Kuenzli, Nino, additional, and Probst-Hensch, Nicole, additional

Published
2011
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