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4,521 results on '"Pizzuto A."'

301. A Search for Coincident Neutrino Emission from Fast Radio Bursts with Seven Years of IceCube Cascade Events

Author

R. Abbasi, M. Ackermann, J. Adams, S. K. Agarwalla, J. A. Aguilar, M. Ahlers, J. M. Alameddine, N. M. Amin, K. Andeen, G. Anton, C. Argüelles, Y. Ashida, S. Athanasiadou, S. N. Axani, X. Bai, A. Balagopal V., M. Baricevic, S. W. Barwick, V. Basu, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, J. Beise, C. Bellenghi, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, F. Bontempo, J. Y. Book, C. Boscolo Meneguolo, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Braun, B. Brinson, J. Brostean-Kaiser, R. T. Burley, R. S. Busse, D. Butterfield, M. A. Campana, K. Carloni, E. G. Carnie-Bronca, S. Chattopadhyay, C. Chen, Z. Chen, D. Chirkin, S. Choi, B. A. Clark, L. Classen, A. Coleman, G. H. Collin, A. Connolly, J. M. Conrad, P. Coppin, P. Correa, S. Countryman, D. F. Cowen, P. Dave, C. De Clercq, J. J. DeLaunay, D. Delgado López, H. Dembinski, K. Deoskar, A. Desai, P. Desiati, K. D. de Vries, G. de Wasseige, T. DeYoung, A. Diaz, J. C. Díaz-Vélez, M. Dittmer, A. Domi, H. Dujmovic, M. A. DuVernois, T. Ehrhardt, P. Eller, R. Engel, H. Erpenbeck, J. Evans, P. A. Evenson, K. L. Fan, K. Fang, A. R. Fazely, A. Fedynitch, N. Feigl, S. Fiedlschuster, C. Finley, L. Fischer, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, P. Fürst, T. K. Gaisser, J. Gallagher, E. Ganster, A. Garcia, S. Garrappa, L. Gerhardt, A. Ghadimi, C. Glaser, T. Glauch, T. Glüsenkamp, N. Goehlke, J. G. Gonzalez, S. Goswami, D. Grant, S. J. Gray, S. Griffin, S. Griswold, C. Günther, P. Gutjahr, C. Haack, A. Hallgren, R. Halliday, L. Halve, F. Halzen, H. Hamdaoui, M. Ha Minh, K. Hanson, J. Hardin, A. A. Harnisch, P. Hatch, A. Haungs, K. Helbing, J. Hellrung, F. Henningsen, L. Heuermann, S. Hickford, A. Hidvegi, C. Hill, G. C. Hill, K. D. Hoffman, K. Hoshina, W. Hou, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, K. Hymon, S. In, N. Iovine, A. Ishihara, M. Jacquart, M. Jansson, G. S. Japaridze, K. Jayakumar, M. Jeong, M. Jin, B. J. P. Jones, D. Kang, W. Kang, X. Kang, A. Kappes, D. Kappesser, L. Kardum, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J. L. Kelley, A. Khatee Zathul, A. Kheirandish, K. Kin, J. Kiryluk, S. R. Klein, A. Kochocki, R. Koirala, H. Kolanoski, T. Kontrimas, L. Köpke, C. Kopper, D. J. Koskinen, P. Koundal, M. Kovacevich, M. Kowalski, T. Kozynets, K. Kruiswijk, E. Krupczak, A. Kumar, E. Kun, N. Kurahashi, N. Lad, C. Lagunas Gualda, M. Lamoureux, M. J. Larson, F. Lauber, J. P. Lazar, J. W. Lee, K. Leonard DeHolton, A. Leszczyńska, M. Lincetto, Q. R. Liu, M. Liubarska, E. Lohfink, C. Love, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, A. Ludwig, W. Luszczak, Y. Lyu, W. Y. Ma, J. Madsen, K. B. M. Mahn, Y. Makino, S. Mancina, W. Marie Sainte, I. C. Mariş, S. Marka, Z. Marka, M. Marsee, I. Martinez-Soler, R. Maruyama, F. Mayhew, T. McElroy, F. McNally, J. V. Mead, K. Meagher, S. Mechbal, A. Medina, M. Meier, S. Meighen-Berger, Y. Merckx, L. Merten, J. Micallef, D. Mockler, T. Montaruli, R. W. Moore, Y. Morii, R. Morse, M. Moulai, T. Mukherjee, R. Naab, R. Nagai, M. Nakos, U. Naumann, J. Necker, M. Neumann, H. Niederhausen, M. U. Nisa, A. Noell, S. C. Nowicki, A. Obertacke Pollmann, V. O’Dell, M. Oehler, B. Oeyen, A. Olivas, R. Orsoe, J. Osborn, E. O’Sullivan, H. Pandya, N. Park, G. K. Parker, E. N. Paudel, L. Paul, C. Pérez de los Heros, J. Peterson, S. Philippen, S. Pieper, A. Pizzuto, M. Plum, Y. Popovych, M. Prado Rodriguez, B. Pries, R. Procter-Murphy, G. T. Przybylski, C. Raab, J. Rack-Helleis, K. Rawlins, Z. Rechav, A. Rehman, P. Reichherzer, G. Renzi, E. Resconi, S. Reusch, W. Rhode, M. Richman, B. Riedel, E. J. Roberts, S. Robertson, S. Rodan, G. Roellinghoff, M. Rongen, C. Rott, T. Ruhe, L. Ruohan, D. Ryckbosch, I. Safa, J. Saffer, D. Salazar-Gallegos, P. Sampathkumar, S. E. Sanchez Herrera, A. Sandrock, M. Santander, S. Sarkar, J. Savelberg, P. Savina, M. Schaufel, H. Schieler, S. Schindler, B. Schlüter, T. Schmidt, J. Schneider, F. G. Schröder, L. Schumacher, G. Schwefer, S. Sclafani, D. Seckel, S. Seunarine, A. Sharma, S. Shefali, N. Shimizu, M. Silva, B. Skrzypek, B. Smithers, R. Snihur, J. Soedingrekso, A. Søgaard, D. Soldin, G. Sommani, C. Spannfellner, G. M. Spiczak, C. Spiering, M. Stamatikos, T. Stanev, R. Stein, T. Stezelberger, T. Stürwald, T. Stuttard, G. W. Sullivan, I. Taboada, S. Ter-Antonyan, W. G. Thompson, J. Thwaites, S. Tilav, K. Tollefson, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, C. F. Tung, R. Turcotte, J. P. Twagirayezu, B. Ty, M. A. Unland Elorrieta, A. K. Upadhyay, K. Upshaw, N. Valtonen-Mattila, J. Vandenbroucke, N. van Eijndhoven, D. Vannerom, J. van Santen, J. Vara, J. Veitch-Michaelis, M. Venugopal, S. Verpoest, D. Veske, C. Walck, T. B. Watson, C. Weaver, P. Weigel, A. Weindl, J. Weldert, C. Wendt, J. Werthebach, M. Weyrauch, N. Whitehorn, C. H. Wiebusch, N. Willey, D. R. Williams, M. Wolf, G. Wrede, J. Wulff, X. W. Xu, J. P. Yanez, E. Yildizci, S. Yoshida, F. Yu, S. Yu, T. Yuan, Z. Zhang, P. Zhelnin, and IceCube Collaboration

Subjects
Neutrino astronomy, Radio transient sources, High energy astrophysics, Astrophysics, QB460-466
Abstract

This paper presents the results of a search for neutrinos that are spatially and temporally coincident with 22 unique, nonrepeating fast radio bursts (FRBs) and one repeating FRB (FRB 121102). FRBs are a rapidly growing class of Galactic and extragalactic astrophysical objects that are considered a potential source of high-energy neutrinos. The IceCube Neutrino Observatory’s previous FRB analyses have solely used track events. This search utilizes seven years of IceCube cascade events which are statistically independent of track events. This event selection allows probing of a longer range of extended timescales due to the low background rate. No statistically significant clustering of neutrinos was observed. Upper limits are set on the time-integrated neutrino flux emitted by FRBs for a range of extended time windows.

Published
2023
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302. Museomics Provides Insights into Conservation and Education: The Instance of an African Lion Specimen from the Museum of Zoology 'Pietro Doderlein'

Author

Elisabetta Cilli, Francesco Fontani, Marta Maria Ciucani, Marcella Pizzuto, Pierangelo Di Benedetto, Sara De Fanti, Thomas Mignani, Carla Bini, Rocco Iacovera, Susi Pelotti, Filippo Spadola, Donata Luiselli, and Sabrina Lo Brutto

Subjects
ancient DNA, biodiversity, conservation, digital restoration, education, lion, Biology (General), QH301-705.5
Abstract

Innovative technological approaches are crucial to enhance naturalistic museum collections and develop information repositories of relevant interest to science, such as threatened animal taxa. In this context, museomics is an emerging discipline that provides a novel approach to the enhancement and exploitation of these collections. In the present study, the discovery of a neglected lion skeleton in the Museum of Zoology “Pietro Doderlein” of the University of Palermo (Italy) offered the opportunity to undertake a multidisciplinary project. The aims of the study consisted of the following: (i) adding useful information for museographic strategies, (ii) obtaining a new genetic data repository from a vulnerable species, (iii) strengthening public awareness of wildlife conservation, and (iv) sharing new learning material. The remains of the lion were examined with a preliminary osteological survey, then they were restored by means of 3D printing of missing skeletal fragments. Phylogenetic analyses based on cytochrome b sequence clearly indicate that the specimen belongs to the Central Africa mitochondrial clade. At the end of the study, the complete and restored skeleton was exhibited, along with all of the information and data available from this project. This study shows a useful approach for the restoration and enhancement of a museum specimen, with important opportunities for preserving biodiversity and driving specific conservation policies, but also for providing Life Science learning material.

Published
2023
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306. Rapid Attentional Selection of Non-native Stimuli despite Perceptual Narrowing

Author

Wu, Rachel, Nako, Rebecca, Band, Jared, Pizzuto, Jacquelyne, Ghoreishi, Yalda, Scerif, Gaia, and Aslin, Richard

Subjects
Basic Behavioral and Social Science, Behavioral and Social Science, Clinical Research, Eye Disease and Disorders of Vision, Adult, Analysis of Variance, Attention, Choice Behavior, Electroencephalography, Evoked Potentials, Visual, Female, Humans, Male, Pattern Recognition, Visual, Photic Stimulation, Reaction Time, Sex Factors, Young Adult, Neurosciences, Psychology, Cognitive Sciences, Experimental Psychology
Abstract

Visual experiences increase our ability to discriminate environmentally relevant stimuli (native stimuli, e.g., human faces) at the cost of a reduced sensitivity to irrelevant or infrequent stimuli (non-native stimuli, e.g., monkey/ape faces)-a developmental progression known as perceptual narrowing. One possible source of the reduced sensitivity in distinguishing non-native stimuli (e.g., one ape face vs. another ape face) could be underspecified attentional search templates (i.e., working memory representations). To determine whether perceptual narrowing stems from underspecified attentional templates for non-native exemplars, this study used ERP (the N2pc component) and behavioral measures in a visual search task, where the target was either an exemplar (e.g., a specific ape face) or a category (e.g., any ape face). The N2pc component, an ERP marker of early attentional selection emerging at 200 msec poststimulus, is typically modulated by the specificity of the target and, therefore, by the attentional template-the N2pc is larger for specific items versus categories. In two experiments using both human and ape faces (i.e., native and non-native stimuli), we found that perceptual narrowing affects later response selection (i.e., manual RT and accuracy), but not early attentional selection relying on attentional templates (i.e., the N2pc component). Our ERP results show that adults deploy exemplar level attentional templates for non-native stimuli (as well as native stimuli), despite poor downstream behavioral performance. Our findings suggest that long-term previous experience with reduced exemplar level judgments (i.e., perceptual narrowing) does not appear to eliminate early attentional selection of non-native exemplars.

Published
2015

308. Exploration of mass splitting and muon/tau mixing parameters for an eV-scale sterile neutrino with IceCube

Author

Abbasi, R., Ackermann, M., Adams, J., Agarwalla, S.K., Aguilar, J.A., Ahlers, M., Alameddine, J.M., Amin, N.M., Andeen, K., Argüelles, C., Ashida, Y., Athanasiadou, S., Ausborm, L., Axani, S.N., Bai, X., Balagopal, A., V, Baricevic, M., Barwick, S.W., Bash, S., Basu, V., Bay, R., Beatty, J.J., Becker Tjus, J., Beise, J., Bellenghi, C., Benning, C., BenZvi, S., Berley, D., Bernardini, E., Besson, D.Z., Blaufuss, E., Bloom, L., Blot, S., Bontempo, F., Book Motzkin, J.Y., Boscolo Meneguolo, C., Böser, S., Botner, O., Böttcher, J., Braun, J., Brinson, B., Brostean-Kaiser, J., Brusa, L., Burley, R.T., Butterfield, D., Campana, M.A., Caracas, I., Carloni, K., Carpio, J., Chattopadhyay, S., Chau, N., Chen, Z., Chirkin, D., Choi, S., Clark, B.A., Coleman, A., Collin, G.H., Connolly, A., Conrad, J.M., Coppin, P., Corley, R., Correa, P., Cowen, D.F., Dave, P., De Clercq, C., DeLaunay, J.J., Delgado, D., Deng, S., Desai, A., Desiati, P., de Vries, K.D., de Wasseige, G., DeYoung, T., Diaz, A., Díaz-Vélez, J.C., Dierichs, P., Dittmer, M., Domi, A., Draper, L., Dujmovic, H., Dutta, K., DuVernois, M.A., Ehrhardt, T., Eidenschink, L., Eimer, A., Eller, P., Ellinger, E., El Mentawi, S., Elsässer, D., Engel, R., Erpenbeck, H., Evans, J., Evenson, P.A., Fan, K.L., Fang, K., Farrag, K., Fazely, A.R., Fedynitch, A., Feigl, N., Fiedlschuster, S., Finley, C., Fischer, L., Fox, D., Franckowiak, A., Fukami, S., Fürst, P., Gallagher, J., Ganster, E., Garcia, A., Garcia, M., Garg, G., Genton, E., Gerhardt, L., Ghadimi, A., Girard-Carillo, C., Glaser, C., Glüsenkamp, T., Gonzalez, J.G., Goswami, S., Granados, A., Grant, D., Gray, S.J., Gries, O., Griffin, S., Griswold, S., Groth, K.M., Günther, C., Gutjahr, P., Ha, C., Haack, C., Hallgren, A., Halve, L., Halzen, F., Hamdaoui, H., Ha Minh, M., Handt, M., Hanson, K., Hardin, J., Harnisch, A.A., Hatch, P., Haungs, A., Häußler, J., Helbing, K., Hellrung, J., Hermannsgabner, J., Heuermann, L., Heyer, N., Hickford, S., Hidvegi, A., Hill, C., Hill, G.C., Hoffman, K.D., Hori, S., Hoshina, K., Hostert, M., Hou, W., Huber, T., Hultqvist, K., Hünnefeld, M., Hussain, R., Hymon, K., Ishihara, A., Iwakiri, W., Jacquart, M., Janik, O., Jansson, M., Japaridze, G.S., Jeong, M., Jin, M., Jones, B.J.P., Kamp, N., Kang, D., Kang, W., Kang, X., Kappes, A., Kappesser, D., Kardum, L., Karg, T., Karl, M., Karle, A., Katil, A., Katz, U., Kauer, M., Kelley, J.L., Khanal, M., Khatee Zathul, A., Kheirandish, A., Kiryluk, J., Klein, S.R., Kochocki, A., Koirala, R., Kolanoski, H., Kontrimas, T., Köpke, L., Kopper, C., Koskinen, D.J., Koundal, P., Kovacevich, M., Kowalski, M., Kozynets, T., Krishnamoorthi, J., Kruiswijk, K., Krupczak, E., Kumar, A., Kun, E., Kurahashi, N., Lad, N., Lagunas Gualda, C., Lamoureux, M., Larson, M.J., Latseva, S., Lauber, F., Lazar, J.P., Lee, J.W., Leonard DeHolton, K., Leszczyńska, A., Liao, J., Lincetto, M., Liu, Y.T., Liubarska, M., Lohfink, E., Love, C., Lozano Mariscal, C.J., Lu, L., Lucarelli, F., Luszczak, W., Lyu, Y., Madsen, J., Magnus, E., Mahn, K.B.M., Makino, Y., Manao, E., Mancina, S., Marie Sainte, W., Mariş, I.C., Marka, S., Marka, Z., Marsee, M., Martinez-Soler, I., Maruyama, R., Mayhew, F., McNally, F., Mead, J.V., Meagher, K., Mechbal, S., Medina, A., Meier, M., Merckx, Y., Merten, L., Micallef, J., Mitchell, J., Montaruli, T., Moore, R.W., Morii, Y., Morse, R., Moulai, M., Mukherjee, T., Naab, R., Nagai, R., Nakos, M., Naumann, U., Necker, J., Negi, A., Neste, L., Neumann, M., Niederhausen, H., Nisa, M.U., Noda, K., Noell, A., Novikov, A., Obertacke Pollmann, A., O'Dell, V., Oeyen, B., Olivas, A., Orsoe, R., Osborn, J., O'Sullivan, E., Pandya, H., Park, N., Parker, G.K., Paudel, E.N., Paul, L., Pérez de los Heros, C., Pernice, T., Peterson, J., Philippen, S., Pizzuto, A., Plum, M., Pontén, A., Popovych, Y., Prado Rodriguez, M., Pries, B., Procter-Murphy, R., Przybylski, G.T., Raab, C., Rack-Helleis, J., Ravn, M., Rawlins, K., Rechav, Z., Rehman, A., Reichherzer, P., Resconi, E., Reusch, S., Rhode, W., Riedel, B., Rifaie, A., Roberts, E.J., Robertson, S., Rodan, S., Roellinghoff, G., Rongen, M., Rosted, A., Rott, C., Ruhe, T., Ruohan, L., Ryckbosch, D., Safa, I., Saffer, J., Salazar-Gallegos, D., Sampathkumar, P., Sandrock, A., Santander, M., Sarkar, S., Savelberg, J., Savina, P., Schaile, P., Schaufel, M., Schieler, H., Schindler, S., Schlüter, B., Schlüter, F., Schmeisser, N., Schmidt, T., Schneider, J., Schröder, F.G., Schumacher, L., Sclafani, S., Seckel, D., Seikh, M., Seo, M., Seunarine, S., Sevle Myhr, P., Shah, R., Shefali, S., Shimizu, N., Silva, M., Skrzypek, B., Smithers, B., Snihur, R., Soedingrekso, J., Søgaard, A., Soldin, D., Soldin, P., Sommani, G., Spannfellner, C., Spiczak, G.M., Spiering, C., Stamatikos, M., Stanev, T., Stezelberger, T., Stürwald, T., Stuttard, T., Sullivan, G.W., Taboada, I., Ter-Antonyan, S., Terliuk, A., Thiesmeyer, M., Thompson, W.G., Thwaites, J., Tilav, S., Tollefson, K., Tönnis, C., Toscano, S., Tosi, D., Trettin, A., Turcotte, R., Twagirayezu, J.P., Unland Elorrieta, M.A., Upadhyay, A.K., Upshaw, K., Vaidyanathan, A., Valtonen-Mattila, N., Vandenbroucke, J., van Eijndhoven, N., Vannerom, D., van Santen, J., Vara, J., Varsi, F., Veitch-Michaelis, J., Venugopal, M., Vereecken, M., Verpoest, S., Veske, D., Vijai, A., Walck, C., Wang, A., Weaver, C., Weigel, P., Weindl, A., Weldert, J., Wen, A.Y., Wendt, C., Werthebach, J., Weyrauch, M., Whitehorn, N., Wiebusch, C.H., Williams, D.R., Witthaus, L., Wolf, A., Wolf, M., Wrede, G., Xu, X.W., Yanez, J.P., Yildizci, E., Yoshida, S., Young, R., Yu, S., Yuan, T., Zhang, Z., Zhelnin, P., Zilberman, P., and Zimmerman, M.

Published
2024
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312. Role of Italian DTT in the power exhaust implementation strategy

Author

Mazzitelli, G., Albanese, R., Crisanti, F., Martin, P., Pizzuto, A., Tuccillo, A.A., Ambrosino, R., Appi, A., Di Gironimo, G., Di Zenobio, A., Frattolillo, A., Granucci, G., Innocente, P., Lampasi, A., Martone, R., Polli, G.M., Ramogida, G., Rossi, P., Sandri, S., Valisa, M., Villari, R., and Vitale, V.

Published
2019
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313. Design review for the Italian Divertor Tokamak Test facility

Author

Albanese, R., Crisanti, F., Martin, P., Pizzuto, A., Mazzitelli, G., Tuccillo, A.A., Ambrosino, R., Appi, A., Di Gironimo, G., Di Zenobio, A., Frattolillo, A., Granucci, G., Innocente, P., Lampasi, A., Martone, R., Polli, G.M., Ramogida, G., Rossi, P., Sandri, S., Valisa, M., Villari, R., and Vitale, V.

Published
2019
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317. Mass Training In Situ During COVID-19 Pandemic: Enhancing Efficiency and Minimizing Sick Leaves

Author

Delamarre, Louis, Couarraze, Sébastien, Vardon-Bounes, Fanny, Marhar, Fouad, Fernandes, Marilyne, Legendre, Muriel, Houze-Cerfon, Charles-Henri, Rigal, Rachel, Pizzuto, Richard, Mathe, Olivier, Larcher, Claire, Ruiz, Jean, Ferré, Fabrice, Riu, Béatrice, Seguin, Thierry, Osinski, Diane, Silva, Stein, Malavaud, Sandra, Georges, Bernard, Minville, Vincent, Fourcade, Olivier, and Geeraerts, Thomas

Published
2022
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318. Is PET/CT Able to Predict Histology in Thymic Epithelial Tumours? A Narrative Review

Author

Marco Chiappetta, Paolo Mendogni, Margherita Cattaneo, Jessica Evangelista, Piero Farina, Daniele Antonio Pizzuto, Salvatore Annunziata, Angelo Castello, Maria Teresa Congedo, Diomira Tabacco, Carolina Sassorossi, Massimo Castellani, Mario Nosotti, Stefano Margaritora, and Filippo Lococo

Subjects
18F-FDG PET/CT, thymoma, thymic epithelial tumour, radiometabolic assessment, WHO, histology, Medicine (General), R5-920
Abstract

Background: The usefulness of 18FDG PET/CT scan in the evaluation of thymic epithelial tumours (TETs) has been reported by several authors, but data are still limited and its application in clinical practice is far from being defined. Methods: We performed a narrative review of pertinent literature in order to clarify the role of 18FDG PET/CT in the prediction of TET histology and to discuss clinical implications and future perspectives. Results: There is only little evidence that 18FDG PET/CT scan may distinguish thymic hyperplasia from thymic epithelial tumours. On the other hand, it seems to discriminate well thymomas from carcinomas and, even more, to predict the grade of malignancy (WHO classes). To this end, SUVmax and other PET variables (i.e., the ratio between SUVmax and tumour dimensions) have been adopted, with good results. Finally, however promising, the future of PET/CT and theranostics in TETs is far from being defined; more robust analysis of imaging texture on thymic neoplasms, as well as new exploratory studies with “stromal PET tracers,” are ongoing. Conclusions: PET may play a role in predicting histology in TETs and help physicians in the management of these insidious malignancies.

Published
2022
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322. Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies

Author

Collier, Dami A., De Marco, Anna, Ferreira, Isabella A. T. M., Meng, Bo, Datir, Rawlings P., Walls, Alexandra C., Kemp, Steven A., Bassi, Jessica, Pinto, Dora, Silacci-Fregni, Chiara, Bianchi, Siro, Tortorici, M. Alejandra, Bowen, John, Culap, Katja, Jaconi, Stefano, Cameroni, Elisabetta, Snell, Gyorgy, Pizzuto, Matteo S., Pellanda, Alessandra Franzetti, Garzoni, Christian, Riva, Agostino, Elmer, Anne, Kingston, Nathalie, Graves, Barbara, McCoy, Laura E., Smith, Kenneth G. C., Bradley, John R., Temperton, Nigel, Ceron-Gutierrez, Lourdes, Barcenas-Morales, Gabriela, Harvey, William, Virgin, Herbert W., Lanzavecchia, Antonio, Piccoli, Luca, Doffinger, Rainer, Wills, Mark, Veesler, David, Corti, Davide, and Gupta, Ravindra K.

Published
2022
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323. Inter‐hospital transfer for thrombectomy: transfer time is brain.

Author

Seners, Pierre, Khyheng, Maeva, Labreuche, Julien, Lapergue, Bertrand, Pico, Fernando, Wang, Adrien, Consoli, Arturo, Coskun, Oguzhan, Di Maria, Federico, Pizzuto, Silvia, Sgreccia, Alessandro, Benoit, Charline, Gorza, Lucas, Weisenburger‐Lile, David, Jabeur, Waliyde, Tchikviladze, Maia, Evrard, Serge, Rodesch, Georges, Blanc, Raphaël, and Obadia, Michel

Subjects
THROMBECTOMY, ISCHEMIC stroke, PUBLIC hospitals, ENDOVASCULAR surgery, STROKE
Abstract

Background and purpose: Patients with acute ischaemic stroke and a large vessel occlusion who present to a non‐endovascular‐capable centre often require inter‐hospital transfer for thrombectomy. Whether the inter‐hospital transfer time is associated with 3‐month functional outcome is poorly known. Methods: Acute stroke patients enrolled between January 2015 and December 2022 in the prospective French multicentre Endovascular Treatment of Ischaemic Stroke registry were retrospectively analysed. Patients with an anterior circulation large vessel occlusion transferred from a non‐endovascular to a comprehensive stroke centre for thrombectomy were eligible. Inter‐hospital transfer time was defined as the time between imaging in the referring hospital and groin puncture for thrombectomy. The relationship between transfer time and favourable 3‐month functional outcome (modified Rankin Scale 0–2) was assessed through a mixed logistic regression model adjusting for centre and symptom‐onset‐to‐referring‐hospital imaging time, age, sex, diabetes, referring hospital National Institutes of Health Stroke Scale score, Alberta Stroke Programme Early Computed Tomography Score, occlusion site and intravenous thrombolysis use. Results: Overall, 3769 patients were included (median inter‐hospital transfer time 161 min, interquartile range 128–195; 46% with favourable outcome). A longer transfer time was independently associated with lower rates of favourable outcome (p < 0.001). Compared to patients with transfer time below 120 min, there was a 15% reduction in the odds of achieving favourable outcome for transfer times between 120 and 180 min (adjusted odds ratio 0.85; 95% confidence interval 0.67–1.07), and a 36% reduction for transfer times beyond 180 min (adjusted odds ratio 0.64; 95% confidence interval 0.50–0.81). Conclusions: A shorter inter‐hospital transfer time is strongly associated with favourable 3‐month functional outcome. A speedier inter‐hospital transfer is of critical importance to improve outcome. [ABSTRACT FROM AUTHOR]

Published
2024
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325. Comprehensive Two-Dimensional Pediatric Echocardiographic Nomograms for Coronary Artery Sizes in Caucasian Children and Comparison among Major Nomograms.

Author

Cantinotti, Massimiliano, Scalese, Marco, Contini, Francesca Valeria, Franchi, Eliana, Viacava, Cecilia, Corana, Giulia, Pizzuto, Alessandra, Pietro, Marchese, Santoro, Giuseppe, and Assanta, Nadia

Subjects
CORONARY arteries, NOMOGRAPHY (Mathematics), ECHOCARDIOGRAPHY, BODY surface area
Abstract

Background: Although coronary artery nomograms in children have been published, data on Caucasian children are lacking. The aim of this study is to provide: (i) a full dataset of coronary artery diameters in healthy children and (ii) a comparison among major previous nomograms. Materials and Methods: We prospectively evaluated 606 healthy subjects (age range, 1 days–<18 years; median age 8.7 years; 62.5% male). Coronary artery measurements in a short-axis view were performed. Age, heart rate, and body surface area (BSA) were used as independent variables in different analyses to predict the mean values of each measurement. To assess the accuracy of the predictive models of different studies, a Z-score calculator was created using Lopez's nomograms for comparison. Results: The association with BSA was found to be stronger, and was used for normalization of our data. The best-fit models, satisfying the assumption of homoscedasticity and normality of residuals and showing the highest R2 scores, were logarithmic (ln[y] = a + b*ln[x]). Predicted values and Z-score boundaries by BSA are provided. Our ranges of normality are slightly lower than those, diverging from −0.22 to −0.59 Z-scores for the left main coronary artery and from −0.23 to −0.3 Z-scores for the right coronary artery. Conclusions: We report a complete dataset of normal echocardiography coronary artery diameter (including new measures of the proximal origin) values in a large population of healthy children. Our data were statistically like those of north American nomograms. [ABSTRACT FROM AUTHOR]

Published
2024
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327. Intravenous Thrombolysis before Complete Angiographic Reperfusion: Beyond Angiographic Assessment to Target Microvascular Obstruction?

Author

Gory, Benjamin, Finitsis, Stephanos, Olivot, Jean‐Marc, Richard, Sébastien, Marnat, Gaultier, Sibon, Igor, Viguier, Alain, Cognard, Christophe, Mazighi, Mikael, Chamorro, Angel, Lapergue, Bertrand, Maïer, Benjamin, Wang, Adrien, Consoli, Arturo, Coskun, Oguzhan, Di Maria, Federico, Pizzuto, Silvia, Sgreccia, Alessandro, Benoit, Charline, and Gorza, Lucas

Subjects
ANGIOGRAPHY, REPERFUSION, INTERNAL carotid artery, INTRACRANIAL hemorrhage, CEREBRAL infarction
Abstract

Objective: Recent data have suggested that ineffective tissue reperfusion despite successful angiographic reperfusion was partly responsible for unfavorable outcomes after endovascular therapy (EVT) and might be modulated by intravenous thrombolysis (IVT) use before EVT. To specifically decipher the effect played by IVT before EVT, we compared the clinical and safety outcomes of patients who experienced a complete reperfusion at the end of EVT according to IVT use before EVT. Methods: The Endovascular Treatment in Ischemic Stroke (ETIS) registry is an ongoing, prospective, observational study at 21 centers that perform EVT in France. Patients were included if they had an anterior large vessel occlusion of the intracranial internal carotid artery or middle cerebral artery (M1/M2 segments) and complete reperfusion (expanded Thrombolysis in Cerebral Infarction score = 3) with EVT within 6 hours, between January 2015 and December 2021. The cohort was divided into two groups according to IVT use before EVT, and propensity score matching (PSM) was used to balance the two groups. Primary outcome was the shift in the degree of disability as measured by the modified Rankin Scale (mRS) at 90 days. Secondary outcomes included favorable outcome (mRS 0–2) at 90 days. Safety outcomes included symptomatic intracranial hemorrhage and 90‐day mortality. Outcomes were estimated with multivariate logistic models adjusted for age, National Institutes of Health Stroke Scale, Alberta Stroke Program Early CT Score, and time from symptom onset to puncture. Results: Among 5,429 patients included in the ETIS registry, 1,093 were included in the study, including 651 patients with complete recanalization treated with IVT before EVT. After PSM, 488 patients treated with IVT before EVT were compared to 337 patients without IVT. In the matched cohort analysis, the IVT+EVT group had a favorable shift in the overall mRS score distribution (adjusted odds ratio [aOR] = 1.41, 95% confidence interval [CI] = 1.04–1.91, p = 0.023) and higher rates of favorable outcome (61.1% vs 48.7%, aOR = 1.49, 95% CI = 1.02–2.20, p = 0.041) at 90 days compared with the EVT alone group. Rates of symptomatic intracerebral hemorrhage were comparable between both groups (6.0% vs 4.3%, aOR = 1.16, 95% CI = 0.53–2.54, p = 0.709). Interpretation: In clinical practice, even after complete angiographic reperfusion by EVT, prior IVT use improves clinical outcomes of patients without increasing bleeding risk. ANN NEUROL 2024;95:762–773 [ABSTRACT FROM AUTHOR]

Published
2024
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331. Unfavorable clinical outcomes in patients with good collateral scores following endovascular treatment for acute ischemic stroke of the anterior circulation: The UNCLOSE study

Author

Consoli, Arturo, primary, Pileggi, Marco, additional, Hasan, ATM Hasibul, additional, Rahman, Mohammad H, additional, Venier, Alice, additional, Sgreccia, Alessandro, additional, Pizzuto, Silvia, additional, Coskun, Oguzhan, additional, Di Maria, Federico, additional, Scarcia, Luca, additional, Lapergue, Bertrand, additional, Rodesch, Georges, additional, Bracard, Serge, additional, and Chen, Bailiang, additional

Published
2023
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334. IceCat-1: The IceCube Event Catalog of Alert Tracks

Author

Abbasi, R., primary, Ackermann, M., additional, Adams, J., additional, Agarwalla, S. K., additional, Aguilar, J. A., additional, Ahlers, M., additional, Alameddine, J. M., additional, Amin, N. M., additional, Andeen, K., additional, Anton, G., additional, Argüelles, C., additional, Ashida, Y., additional, Athanasiadou, S., additional, Axani, S. N., additional, Bai, X., additional, Balagopal V, A., additional, Baricevic, M., additional, Barwick, S. W., additional, Basu, V., additional, Bay, R., additional, Beatty, J. J., additional, Becker, K.-H., additional, Becker Tjus, J., additional, Beise, J., additional, Bellenghi, C., additional, BenZvi, S., additional, Berley, D., additional, Bernardini, E., additional, Besson, D. Z., additional, Binder, G., additional, Bindig, D., additional, Blaufuss, E., additional, Blot, S., additional, Bontempo, F., additional, Book, J. Y., additional, Boscolo Meneguolo, C., additional, Böser, S., additional, Botner, O., additional, Böttcher, J., additional, Bourbeau, E., additional, Braun, J., additional, Brinson, B., additional, Brostean-Kaiser, J., additional, Burley, R. T., additional, Busse, R. S., additional, Butterfield, D., additional, Campana, M. A., additional, Carloni, K., additional, Carnie-Bronca, E. G., additional, Chattopadhyay, S., additional, Chau, N., additional, Chen, C., additional, Chen, Z., additional, Chirkin, D., additional, Choi, S., additional, Clark, B. A., additional, Classen, L., additional, Coleman, A., additional, Collin, G. H., additional, Connolly, A., additional, Conrad, J. M., additional, Coppin, P., additional, Correa, P., additional, Countryman, S., additional, Cowen, D. F., additional, Dave, P., additional, De Clercq, C., additional, DeLaunay, J. J., additional, Delgado, D., additional, Dembinski, H., additional, Deng, S., additional, Deoskar, K., additional, Desai, A., additional, Desiati, P., additional, de Vries, K. D., additional, de Wasseige, G., additional, DeYoung, T., additional, Diaz, A., additional, Díaz-Vélez, J. C., additional, Dittmer, M., additional, Domi, A., additional, Dujmovic, H., additional, DuVernois, M. A., additional, Ehrhardt, T., additional, Eller, P., additional, Engel, R., additional, Erpenbeck, H., additional, Evans, J., additional, Evenson, P. A., additional, Fan, K. L., additional, Fang, K., additional, Farrag, K., additional, Fazely, A. R., additional, Fedynitch, A., additional, Feigl, N., additional, Fiedlschuster, S., additional, Finley, C., additional, Fischer, L., additional, Fox, D., additional, Franckowiak, A., additional, Friedman, E., additional, Fritz, A., additional, Fürst, P., additional, Gaisser, T. K., additional, Gallagher, J., additional, Ganster, E., additional, Garcia, A., additional, Gerhardt, L., additional, Ghadimi, A., additional, Glaser, C., additional, Glauch, T., additional, Glüsenkamp, T., additional, Goehlke, N., additional, Gonzalez, J. G., additional, Goswami, S., additional, Grant, D., additional, Gray, S. J., additional, Griffin, S., additional, Griswold, S., additional, Günther, C., additional, Gutjahr, P., additional, Haack, C., additional, Hallgren, A., additional, Halliday, R., additional, Halve, L., additional, Halzen, F., additional, Hamdaoui, H., additional, Ha Minh, M., additional, Hanson, K., additional, Hardin, J., additional, Harnisch, A. A., additional, Hatch, P., additional, Haungs, A., additional, Helbing, K., additional, Hellrung, J., additional, Henningsen, F., additional, Heuermann, L., additional, Heyer, N., additional, Hickford, S., additional, Hidvegi, A., additional, Hill, C., additional, Hill, G. C., additional, Hoffman, K. D., additional, Hoshina, K., additional, Hou, W., additional, Huber, T., additional, Hultqvist, K., additional, Hünnefeld, M., additional, Hussain, R., additional, Hymon, K., additional, In, S., additional, Ishihara, A., additional, Jacquart, M., additional, Janik, O., additional, Jansson, M., additional, Japaridze, G. S., additional, Jayakumar, K., additional, Jeong, M., additional, Jin, M., additional, Jones, B. J. P., additional, Kang, D., additional, Kang, W., additional, Kang, X., additional, Kappes, A., additional, Kappesser, D., additional, Kardum, L., additional, Karg, T., additional, Karl, M., additional, Karle, A., additional, Katz, U., additional, Kauer, M., additional, Kelley, J. L., additional, Zathul, A. Khatee, additional, Kheirandish, A., additional, Kiryluk, J., additional, Klein, S. R., additional, Kochocki, A., additional, Koirala, R., additional, Kolanoski, H., additional, Kontrimas, T., additional, Köpke, L., additional, Kopper, C., additional, Koskinen, D. J., additional, Koundal, P., additional, Kovacevich, M., additional, Kowalski, M., additional, Kozynets, T., additional, Kruiswijk, K., additional, Krupczak, E., additional, Kumar, A., additional, Kun, E., additional, Kurahashi, N., additional, Lad, N., additional, Lagunas Gualda, C., additional, Lamoureux, M., additional, Larson, M. J., additional, Lauber, F., additional, Lazar, J. P., additional, Lee, J. W., additional, Leonard DeHolton, K., additional, Leszczyńska, A., additional, Lincetto, M., additional, Liu, Q. R., additional, Liubarska, M., additional, Lohfink, E., additional, Love, C., additional, Lozano Mariscal, C. J., additional, Lu, L., additional, Lucarelli, F., additional, Ludwig, A., additional, Luszczak, W., additional, Lyu, Y., additional, Madsen, J., additional, Mahn, K. B. M., additional, Makino, Y., additional, Manao, E., additional, Mancina, S., additional, Marie Sainte, W., additional, Mariş, I. C., additional, Marka, S., additional, Marka, Z., additional, Marsee, M., additional, Martinez-Soler, I., additional, Maruyama, R., additional, Mayhew, F., additional, McElroy, T., additional, McNally, F., additional, Mead, J. V., additional, Meagher, K., additional, Mechbal, S., additional, Medina, A., additional, Meier, M., additional, Merckx, Y., additional, Merten, L., additional, Micallef, J., additional, Montaruli, T., additional, Moore, R. W., additional, Morii, Y., additional, Morse, R., additional, Moulai, M., additional, Mukherjee, T., additional, Naab, R., additional, Nagai, R., additional, Nakos, M., additional, Naumann, U., additional, Necker, J., additional, Neumann, M., additional, Niederhausen, H., additional, Nisa, M. U., additional, Noell, A., additional, Nowicki, S. C., additional, Obertacke Pollmann, A., additional, O’Dell, V., additional, Oehler, M., additional, Oeyen, B., additional, Olivas, A., additional, Orsoe, R., additional, Osborn, J., additional, O’Sullivan, E., additional, Pandya, H., additional, Park, N., additional, Parker, G. K., additional, Paudel, E. N., additional, Paul, L., additional, Pérez de los Heros, C., additional, Peterson, J., additional, Philippen, S., additional, Pieper, S., additional, Pizzuto, A., additional, Plum, M., additional, Pontén, A., additional, Popovych, Y., additional, Prado Rodriguez, M., additional, Pries, B., additional, Procter-Murphy, R., additional, Przybylski, G. T., additional, Rack-Helleis, J., additional, Rawlins, K., additional, Rechav, Z., additional, Rehman, A., additional, Reichherzer, P., additional, Renzi, G., additional, Resconi, E., additional, Reusch, S., additional, Rhode, W., additional, Richman, M., additional, Riedel, B., additional, Roberts, E. J., additional, Robertson, S., additional, Rodan, S., additional, Roellinghoff, G., additional, Rongen, M., additional, Rott, C., additional, Ruhe, T., additional, Ruohan, L., additional, Ryckbosch, D., additional, Safa, I., additional, Saffer, J., additional, Salazar-Gallegos, D., additional, Sampathkumar, P., additional, Sanchez Herrera, S. E., additional, Sandrock, A., additional, Santander, M., additional, Sarkar, S., additional, Savelberg, J., additional, Savina, P., additional, Schaufel, M., additional, Schieler, H., additional, Schindler, S., additional, Schlüter, B., additional, Schlüter, F., additional, Schmidt, T., additional, Schneider, J., additional, Schröder, F. G., additional, Schumacher, L., additional, Schwefer, G., additional, Sclafani, S., additional, Seckel, D., additional, Seunarine, S., additional, Shah, R., additional, Sharma, A., additional, Shefali, S., additional, Shimizu, N., additional, Silva, M., additional, Skrzypek, B., additional, Smithers, B., additional, Snihur, R., additional, Soedingrekso, J., additional, Søgaard, A., additional, Soldin, D., additional, Sommani, G., additional, Spannfellner, C., additional, Spiczak, G. M., additional, Spiering, C., additional, Stamatikos, M., additional, Stanev, T., additional, Stezelberger, T., additional, Stürwald, T., additional, Stuttard, T., additional, Sullivan, G. W., additional, Taboada, I., additional, Ter-Antonyan, S., additional, Thiesmeyer, M., additional, Thompson, W. G., additional, Thwaites, J., additional, Tilav, S., additional, Tollefson, K., additional, Tönnis, C., additional, Toscano, S., additional, Tosi, D., additional, Trettin, A., additional, Tung, C. F., additional, Turcotte, R., additional, Twagirayezu, J. P., additional, Ty, B., additional, Unland Elorrieta, M. A., additional, Upadhyay, A. K., additional, Upshaw, K., additional, Valtonen-Mattila, N., additional, Vandenbroucke, J., additional, van Eijndhoven, N., additional, Vannerom, D., additional, van Santen, J., additional, Vara, J., additional, Veitch-Michaelis, J., additional, Venugopal, M., additional, Verpoest, S., additional, Veske, D., additional, Walck, C., additional, Watson, T. B., additional, Weaver, C., additional, Weigel, P., additional, Weindl, A., additional, Weldert, J., additional, Wendt, C., additional, Werthebach, J., additional, Weyrauch, M., additional, Whitehorn, N., additional, Wiebusch, C. H., additional, Willey, N., additional, Williams, D. R., additional, Wolf, A., additional, Wolf, M., additional, Wrede, G., additional, Xu, X. W., additional, Yanez, J. P., additional, Yildizci, E., additional, Yoshida, S., additional, Yu, F., additional, Yu, S., additional, Yuan, T., additional, Zhang, Z., additional, and Zhelnin, P., additional

Published
2023
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335. Spatial communication systems across languages reflect universal action constraints

Author

Coventry, Kenny R., primary, Gudde, Harmen B., additional, Diessel, Holger, additional, Collier, Jacqueline, additional, Guijarro-Fuentes, Pedro, additional, Vulchanova, Mila, additional, Vulchanov, Valentin, additional, Todisco, Emanuela, additional, Reile, Maria, additional, Breunesse, Merlijn, additional, Plado, Helen, additional, Bohnemeyer, Juergen, additional, Bsili, Raed, additional, Caldano, Michela, additional, Dekova, Rositsa, additional, Donelson, Katharine, additional, Forker, Diana, additional, Park, Yesol, additional, Pathak, Lekhnath Sharma, additional, Peeters, David, additional, Pizzuto, Gabriella, additional, Serhan, Baris, additional, Apse, Linda, additional, Hesse, Florian, additional, Hoang, Linh, additional, Hoang, Phuong, additional, Igari, Yoko, additional, Kapiley, Keerthana, additional, Haupt-Khutsishvili, Tamar, additional, Kolding, Sara, additional, Priiki, Katri, additional, Mačiukaitytė, Ieva, additional, Mohite, Vaisnavi, additional, Nahkola, Tiina, additional, Tsoi, Sum Yi, additional, Williams, Stefan, additional, Yasuda, Shunei, additional, Cangelosi, Angelo, additional, Duñabeitia, Jon Andoni, additional, Mishra, Ramesh Kumar, additional, Rocca, Roberta, additional, Šķilters, Jurģis, additional, Wallentin, Mikkel, additional, Žilinskaitė-Šinkūnienė, Eglė, additional, and Incel, Ozlem Durmaz, additional

Published
2023
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337. Mid-Term Electrical Remodeling after Percutaneous Atrial Septal Defect Closure with GCO Device in a Pediatric Population

Author

Fumanelli, Jennifer, primary, Garibaldi, Silvia, additional, Castaldi, Biagio, additional, Di Candia, Angela, additional, Pizzuto, Alessandra, additional, Sirico, Domenico, additional, Cuman, Magdalena, additional, Mirizzi, Gianluca, additional, Marchese, Pietro, additional, Cantinotti, Massimiliano, additional, Piacenti, Marcello, additional, Assanta, Nadia, additional, Viacava, Cecilia, additional, Di Salvo, Giovanni, additional, and Santoro, Giuseppe, additional

Published
2023
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339. Search for steady point-like sources in the astrophysical muon neutrino flux with 8 years of IceCube data

Author

IceCube Collaboration, M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Barbano, J. P. Barron, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, S. Böser, O. Botner, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, H.-P. Bretz, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, T. Carver, C. Chen, E. Cheung, D. Chirkin, K. Clark, L. Classen, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, M. Day, J. P. A. M. de André, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, H. Dujmovic, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, A. Franckowiak, E. Friedman, A. Fritz, T. K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, K. Ghorbani, W. Giang, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, P. Kalaczynski, W. Kang, A. Kappes, D. Kappesser, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, S. Kunwar, N. Kurahashi, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, K. Leonard, M. Leuermann, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, J. Lünemann, W. Luszczak, J. Madsen, G. Maggi, K. B. M. Mahn, Y. Makino, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, R. Maunu, K. Meagher, M. Medici, M. Meier, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, M. Moulai, R. Nagai, R. Nahnhauer, P. Nakarmi, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, E. O’Sullivan, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, C. Pérez de los Heros, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, P. B. Price, G. T. Przybylski, C. Raab, M. Rameez, L. Rauch, K. Rawlins, I. C. Rea, R. Reimann, B. Relethford, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, S. Schöneberg, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, J. Soedingrekso, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, A. Stasik, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, M. Sutherland, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, M. N. Tobin, C. Tönnis, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, F. D. Wandler, N. Wandkowsky, T. B. Watson, C. Weaver, M. J. Weiss, C. Wendt, J. Werthebach, S. Westerhoff, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, E. Woolsey, K. Woschnagg, G. Wrede, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, and T. Yuan

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The IceCube Collaboration has observed a high-energy astrophysical neutrino flux and recently found evidence for neutrino emission from the blazar TXS 0506$$+$$ + 056. These results open a new window into the high-energy universe. However, the source or sources of most of the observed flux of astrophysical neutrinos remains uncertain. Here, a search for steady point-like neutrino sources is performed using an unbinned likelihood analysis. The method searches for a spatial accumulation of muon-neutrino events using the very high-statistics sample of about 497,000 neutrinos recorded by IceCube between 2009 and 2017. The median angular resolution is $$\sim 1^\circ $$ ∼1∘ at 1 TeV and improves to $$\sim 0.3^\circ $$ ∼0.3∘ for neutrinos with an energy of 1 PeV. Compared to previous analyses, this search is optimized for point-like neutrino emission with the same flux-characteristics as the observed astrophysical muon-neutrino flux and introduces an improved event-reconstruction and parametrization of the background. The result is an improvement in sensitivity to the muon-neutrino flux compared to the previous analysis of $$\sim 35\%$$ ∼35% assuming an $$E^{-2}$$ E-2 spectrum. The sensitivity on the muon-neutrino flux is at a level of $$E^2 \mathrm {d} N /\mathrm {d} E = 3\cdot 10^{-13}\,\mathrm {TeV}\,\mathrm {cm}^{-2}\,\mathrm {s}^{-1}$$ E2dN/dE=3·10-13TeVcm-2s-1 . No new evidence for neutrino sources is found in a full sky scan and in an a priori candidate source list that is motivated by gamma-ray observations. Furthermore, no significant excesses above background are found from populations of sub-threshold sources. The implications of the non-observation for potential source classes are discussed.

Published
2019
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340. Mass Training In Situ During COVID-19 Pandemic: Enhancing Efficiency and Minimizing Sick Leaves

Author

Delamarre, Louis, Couarraze, Sébastien, Vardon-Bounes, Fanny, Marhar, Fouad, Fernandes, Marilyne, Legendre, Muriel, Houze-Cerfon, Charles-Henri, Rigal, Rachel, Pizzuto, Richard, Mathe, Olivier, Larcher, Claire, Ruiz, Jean, Ferré, Fabrice, Riu, Béatrice, Seguin, Thierry, Osinski, Diane, Silva, Stein, Malavaud, Sandra, Georges, Bernard, Minville, Vincent, Fourcade, Olivier, and Geeraerts, Thomas

Published
2021
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342. A three-year post-graduate Doctorate in Pharmacy course incorporating professional, experiential and research activities: A collaborative innovative approach

Author

Janis Vella, Maresca Attard Pizzuto, Nicolette Sammut Bartolo, Francesca Wirth, Louise Grech, Jennifer Pham, Christina Mactal Haaf, Alan Lau, Anthony Serracino Inglott, and Lilian M. Azzopardi

Subjects
Bologna declaration, Doctorate in Pharmacy, leadership, Pharmacy education, Special aspects of education, LC8-6691, Medicine
Abstract

Background A three-year post-graduate international Doctorate in Pharmacy collaborative course, was launched by the Department of Pharmacy, University of Malta in collaboration with the College of Pharmacy, University of Illinois at Chicago. Aim and rationale To demonstrate that the professional Doctorate in Pharmacy (i) fits the requirements of a Level 8 degree according to the Bologna process, (ii) helps graduates develop competencies and attributes in proficiency in clinical and professional aspects, (iii) has a research component that provides the right level of abilities to participate in research initiatives and to interpret research outcomes, (iv) enables graduates to obtain leadership characteristics. Approach The unique characteristics of the course were evaluated through an outcomes result-oriented measurement. Leadership aspects were measured through policies and strategies presented by students and graduates. Outcomes i) course is in line with the Bologna declaration, ii) research work shown in the dissertation satisfied competencies required iii) research abilities have been examined through a third party and found to be compliant with acquiring of concepts in the design, carrying out, assessment of outcomes and interpretation of results of the research study carried out by each student, and iv) leadership characteristics were shown by the positions taken up by the graduates and early outcomes from these positions. Conclusion Learning activities enable development of professionals able to merge scientific and practice aspects in the evaluation of innovative therapies, the use of medicines and patient monitoring, and in pharmaceutical policy development and regulation. Leadership positions taken up by graduates point to the acquisition of leadership skills by graduates. Next Steps The authors are happy to extend collaboration for this model to be adapted by other institutions for the curricular development entailed in this programme to enhance and improve an innovative aspect in the evolvement of the pharmacy profession on the international scenario.

Published
2021

347. Listening to the Voices of Young Children in a Nurture Class

Author

Cefai, Carmel and Pizzuto, Sue Anne Spiteri

Abstract

The inclusion of the student perspective in helping to promote more effective learning, engagement and positive behaviour is becoming increasingly evident in both educational research and school and classroom practice. Giving students the opportunity to have a meaningful and influential voice enhances both the teaching and learning processes, impacting both academic and social behaviours. The student voice perspective is also making inroads into the area of special educational needs, where children are participating more actively in their own assessment and individual educational plans. This paper presents the findings of a project in a nurture class (NC) in Malta which sought to capture the views of the pupils attending NCs. Through a child friendly, qualitative approach young children were given the opportunity to discuss and express their feelings and thoughts of what it means for them to be a pupil in a NC in primary school. The paper presents the themes which emerged from a thematic analysis of children's voices during semi-structured group interviews and collaborative mapping and poster design, and concludes with suggestions on how the NC may operate as a more child friendly space at the school.

Published
2017
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