301. Obstructive sleep apnea is highly prevalent and correlates with impaired glycemic control in consecutive patients with the metabolic syndrome
- Author
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Luciano F. Drager, Heno Ferreira Lopes, Geraldo Lorenzi-Filho, Eduardo M. Krieger, Eduardo L. Queiroz, and Pedro R. Genta
- Subjects
Adult ,Blood Glucose ,Male ,medicine.medical_specialty ,Cross-sectional study ,Endocrinology, Diabetes and Metabolism ,Polysomnography ,Severity of Illness Index ,Body Mass Index ,stomatognathic system ,Internal medicine ,Severity of illness ,Internal Medicine ,medicine ,Prevalence ,Humans ,Glycemic ,Aged ,Glycated Hemoglobin ,Metabolic Syndrome ,Sleep Apnea, Obstructive ,medicine.diagnostic_test ,business.industry ,Anthropometry ,Middle Aged ,medicine.disease ,nervous system diseases ,respiratory tract diseases ,Obstructive sleep apnea ,Endocrinology ,Cross-Sectional Studies ,Hyperglycemia ,Female ,Metabolic syndrome ,Cardiology and Cardiovascular Medicine ,business ,Body mass index ,Biomarkers - Abstract
Obstructive sleep apnea (OSA) and the metabolic syndrome (MS) are independently associated with increased cardiovascular risk. The objective of the present study was to determine the prevalence of OSA among consecutive patients with MS and to determine whether OSA is associated with impaired glycemic control. Fifty consecutive patients with a recent diagnosis of MS and no previous diagnosis of OSA underwent a polysomnography and anthropometric and laboratory measurements. The prevalence of OSA (apnea-hypopnea index >or=15 events per hour of sleep) was 68% and in the same range of all other individual components of MS. Moreover, OSA was associated with increased levels of glucose (P=.03) and glycosylated hemoglobin (P=.03) but not with body mass index (P=.30). Glycosylated hemoglobin was independently associated with glucose (P
- Published
- 2009