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Surface preparation is potentially important to the corrosion and biomedical properties of NiTi shape memory alloys. The effect of surface preparation on corrosion properties and nickel release of a Ti-56 wt.% Ni alloy has been studied. Surface of the NiTi coupons were prepared by four methods, namely, chemical etching, electropolishing, mechanical polishing and oxidizing, and then examined by corrosion test system. Furthermore, the Ni ion releases from NiTi samples with different surface preparations dipped in 1% HCl solution were analysed. Compared with the surface after chemical treatment, mechanical polishing and thermal oxidation, electropolished surface has better corrosion resistance and less nickel release for not only its lower surface roughness, but also the composition and property of its surface film.

Electropolishing has been used in NiTi alloy in several fields for its special characteristics, but its essential details and electropolishing mechanism have not been reported yet as a demand from business competition, which, to a great degree, restricts the application and extension of the electropolishing technology. The effect of processing parameters on nitinol electropolishing was explored. Besides the electrolyte, other factors that influence the electropolishing are temperature, current density, time, spacing between anode and cathode, electrolyte stirring, etc. Studies on the effect of the temperature on the electropolishing process show that the higher the temperature is, the bigger the electropolishing rate is, following the near Gauss law. The relationship between the temperature and the surface roughness follows a near parabolic law, and the relationship between the temperature and the surface reflectivity follows a near sigmoidal law. The relationship between the electropolishing voltage and the current density follows a near cubic law, while that between the electropolishing rate and current density follows a near linear law. The relationship between the electropolishing rate and the time follows a near sigmoidal law. The practical spacing between anode and cathode is confirmed by the Hall bath experiment.

To explore the expression and clinical significance of Slug, E-cadherin and N-cadherin in gastrointestinal stromal tumors (GIST).Seventy eight GIST specimens removed surgically from 2004 to 2007 were collected from the Department of Gastrointestinal Surgery at Guizhou Provincial People's Hospital. There were 48 males and 30 females with an age range of 28 - 87 years old. The expressions of Slug, E-cadherin and N-cadherin in GIST were determined by immunohistochemistry. And the correlations with their clinicopathologic characteristics were analyzed.The positive rates of Slug, E-cadherin and N-cadherin in GIST were 53.8% (42/78), 35.9% (28/78) and 75.6% (59/78) respectively. And the differences were statistically significant (χ(2) = 24.98, P0.05). Slug was expressed markedly higher in the cases of GIST with distant metastasis or distant metastasis and local invasion: 75% (18/24) vs 44.4% (24/54), 63.6% (28/44) vs 41.2% (14/34), both P0.05. And E-cadherin was expressed markedly lower in the cases of GIST with distant metastasis: 16.7% (4/24) vs 44.4% (24/54), P0.05. The expression of N-cadherin was not significantly different between its clinicopathological characteristics (allP0.05). The expression of Slug correlated negatively with that of E-cadherin (r(s) = -0.267, P = 0.018). But it had no correlation with that of N-cadherin (r(s) = 0.056, P = 0.625).Slug is expressed markedly higher while E-cadherin markedly lower in metastatic GIST, and both are closely correlated with the metastasis of GIST.

Patients with obsessive-compulsive disorder (OCD) have increased rates of neurological soft signs (NSS) when compared to healthy controls. However, previous findings have been confounded by the presence of co-morbidity with disorders themselves associated with increased NSS, such as schizophrenia. Moreover, it remains unclear whether NSS in OCD reflect a vulnerability to this disorder. This study aimed to examine: 1) the severity of NSS in patients with OCD alone, in patients with OCD and co-morbid psychosis (schizophrenia or bipolar disorders), and in healthy controls; and b) whether unaffected first-degree relatives of patients with OCD also demonstrate a higher prevalence rate of NSS than healthy controls. NSS were assessed with the Cambridge Neurological Inventory (CNI) in 100 patients with OCD, 38 patients with OCD and psychosis (22 with bipolar disorders and 16 with schizophrenia), and 101 healthy controls. Forty-seven unaffected first-degree relatives of patients with OCD only were also administered the CNI. Patients with OCD showed significantly higher scores in motor coordination and total NSS than controls, and patients with OCD co-morbid with psychosis also showed significantly higher scores in motor coordination and total NSS than controls. Although there were no differences in NSS between patients with OCD only and OCD and psychosis as a whole, patients with OCD co-morbid with schizophrenia showed significantly higher scores in motor coordination than patients with OCD, patients with OCD and bipolar disorder, and healthy controls. Unaffected first-degree relatives only showed a higher prevalence rate than healthy controls in specific motor coordination signs, such as Opposition and Extinction. These findings suggest that patients with OCD exhibit more NSS than healthy controls, and that motor coordination signs may be even more extensive when OCD is co-morbid with psychosis. Some of these abnormalities may be indicative of a vulnerability to these disorders, as indicated by their presence in un-affected first-degree relatives. (c) 2012 Elsevier Inc. All rights reserved.

Introduction Specific cortico-striato-thalamic circuits are hypothesised to underlie the aetiology of obsessive-compulsive disorder (OCD). However, findings from neuroimaging studies have been inconsistent. In the current study, we attempted to provide a complete overview of structural alterations in OCD by conducting signed differential mapping (SDM) meta-analysis on grey matter and white matter studies of patients with OCD based on voxel-based morphometry (VBM) studies and diffusion tensor imaging (DTI) studies. Methods Fifteen VBM and seven DTI case–control studies were included in this meta-analysis. SDM meta-analyses were performed to assess grey matter volume and white matter integrity changes in OCD patients and healthy controls. Results We found that OCD patients had smaller grey matter volume than health controls in the frontal eye fields, medial frontal gyrus and anterior cingulate cortex. However, we showed that there was an increase in the grey matter volume in the lenticular nucleus, caudate nucleus and a small region in the right superior parietal lobule. OCD patients also had a lower fractional anisotropy (FA) in the cingulum bundles, inferior fronto-occipital fasciculus, and superior longitudinal fasciculus, while increased FA in the left uncinate fasciculus. Conclusions The current findings confirm the structural abnormalities of cortico-striato-thalamic circuits in OCD.

Cerebrotendinous xanthomatosis is a rare, autosomal-recessive, lipid-storage disease with accumulation of cholestanol in most tissues, particularly within the Achilles tendons. It has been characterized both clinically and biochemically, and recently from the molecular biological aspect as well. Juvenile cataract, childhood diarrhea, mental retardation, cerebellar ataxia, and tendon xanthomas are the most prominent features of this disease. Bilateral symmetrical firm masses of Achilles tendons may be the first symptom the patient recognizes because it can jeopardize his or her ability to walk. However, the treatment strategies for tendon tumors vary. In a recent case, we diagnosed the disease properly, according to the clinical manifestations and the radiological and laboratory examinations. The genetic mutation was characterized by analyzing sterol 27-hydroxylase from the patient’s family (located on nucleotide 599) and led to a nonsense mutation. It is a unique type of mutation that has never been reported to our knowledge. Tendon lesions are characterized by the loss of muscle fibers and accumulation of lipid products. To help the patient regain the strength of the Achilles tendon and walking abilities, a large area of tendon tumor was excised, followed by reconstruction with a tibialis posterior allograft, which is the second strongest tendon in the foot and ankle. Although the use of this type of graft is uncommon, the final result was satisfactory. At the 10-month follow-up examination, the patient could walk easily without pain. This case report suggests that the surgical procedure will provide an alternative for the repair of large-area degenerative Achilles tendons.

To assess the safety and feasibility of laparoscopic and open repair of perforated peptic ulcer.Studies on comparison between laparoscopic repair(LR) and open repair(OR) of perforated peptic ulcer were collected. Data of operating time, blood loss, time to first flatus, postoperative hospital stay, postoperative complications and mortality between LR group and OR group were meta-analyzed using fixed effect model and random effect model.Nineteen studies including 1507 patients were selected for this study,including laparoscopic surgery(n=673) and open surgery(n=834). There were significant differences in blood loss, time to first flatus, postoperative hospital stay, wound infection rate and mortality between LR group and OR group. However, no significant differences existed in operative time, postoperative sepsis, pulmonary infection, abdominal abscess, and suture leakage between the two groups.Laparoscopic repair of perforated peptic ulcer is associated with improved outcomes in terms of less blood loss, quicker recovery, and lower rates of wound infection and mortality. Laparoscopic repair of perforated peptic ulcer is safe and feasible.

Background The Obsessive-Compulsive Inventory-Revised (OCI-R) was designed to evaluate the severity of obsessive-compulsive symptoms in both clinical and non-clinical samples. The aim of the study was to evaluate the psychometric properties of a Chinese version of this scale. Methods The Chinese version of the OCI-R was administered to both a non-clinical sample (209 undergraduate students) and a clinical sample (56 obsessive-compulsive disorder (OCD) patients). Confirmatory factor analysis was conducted to examine the construct validity of the OCI-R in the non-clinical sample. The internal consistency at baseline and test-retest reliabilities at 4-week interval was examined in both the non-clinical and clinical samples. Results The confirmatory factor analysis of the non-clinical sample confirmed a 6-factor model suggested by the original authors of the instrument (df = 120, RMSEA = 0.068, CFI = 0.88, NNFI = 0.85, GFI = 0.89). The internal consistency and test-retest reliability were at an acceptable range for both the non-clinical and clinical samples. The OCI-R also showed good clinical discrimination for patients with OCD from healthy controls. Conclusions The Chinese version of the OCI-R is a valid and reliable instrument for measuring OCD symptoms in the Chinese context.

The bacterial redox protein azurin selectively induces apoptosis in human osteosarcoma U2OS cells. We constructed a p53 siRNA to test the role that p53 plays in the apoptosis-inducing role of azurin in U2OS cells. Cells treated with p53 siRNA and azurin showed more viable cells, a lower apoptosis rate, lower caspase-3 activity, and up-regulation of bcl-2, downregulation of bax compared to cells treated with negative siRNA and azurin. Cells treated with negative siRNA and azurin yielded positive TUNEL dying, whereas cells treated with p53 siRNA and azurin yielded few positive cells. These results suggested that p53 siRNA was capable of inhibi-ting the apoptosis induced by azurin 2 days after treatment with p53 siRNA and azurin. Azurin may induce apoptosis through combination with p53. The decrease in p53 protein levels did not inhibit cell apoptosis rates, but rather increased these rates in U2OS osteosarcoma cells 3 days after treatment with p53 siRNA. Since U2OS cells are p53 wild-type cancer cells, p53 potentially acts as an oncogene in U2OS osteosarcoma cells. Treatment with azurin may transform the function of p53 from inhibiting to inducing apoptosis.

To investigate the relationship between methylation of the CDH1 gene promoter on the expression of E-cadherin and β-catenin, and to evaluate the correlation with clinicopathological characteristics of the colonic carcinoma.Methylation specific PCR (MSP) was used to detect CDH1 gene promoter methylation in the cancer tissue, adjacent tissues and normal tissues in 68 patients. The expression of E-cadherin and β-catenin was determined by immunohistochemistry staining.The positive rate of CDH1 gene promoter methylation was 32.4% in adjacent tissues and 57.4% in cancer tissue, while no detectable methylation was found in all the normal tissues. The difference was statistically significant. The positive rate of E-cadherin was 92.6% in the normal tissues, 66.2% in the adjacent tissues and 44.1% in the cancer tissues. In all normal tissues, β-catenin was expressed only at the cellular membrane but not in the cytosol or nucleus, while the expression of β-catenin was present in the cytosol or nucleus in 29.4% of the adjacent tissues and 50.0% of the cancer tissues. The positive rate of CDH1 gene promoter methylation was negatively correlated with E-cadherin expression(r=-0.312, P=0.01) and positively correlated with β-catenin cytosolic/nucleus expression(r=0.309, P=0.018). The differentiation and metastasis of colonic carcinoma were associated with the aberrant expression of E-cadherin, β-catenin, and methylation of CDH1 promoter (P0.05).CDH1 gene promoter methylation may lead to aberrant expression of E-cadherin and β-catenin in colonic carcinoma, and may play an important role in promoting the invasion of tumor.

To evaluate the necessity of splenectomy in radical resection of gastric cancer.Twelve studies comparing outcomes after radical resection of gastric cancer with or without splenectomy were identified. Both fixed effect model and random effect model were used.There were 2628 patients in total. There were significant differences in complications between splenectomy group and spleen-preserving group(OR=1.91, 95% CI:1.28-2.87, P0.05), while no significant difference in 5-year survival rate was noticed(HR=0.90, 95% CI:0.73-1.11, P0.05).Radical resection of gastric cancer combined with splenectomy is not associated with improved survival but increased postoperative complications.

To investigate individualized one-staged correction of alveolar cleft and lip and nasal deformities secondary to lip cleft.The alveolar cleft and lip and nasal deformities secondary to lip cleft were corrected in one stage.From 2004 to 2007, 37 cases were treated. 33 patients were treated successfully with primary healing in bony recipient area. Cancellous bone exposure happened in 3 cases. The wounds healed after debridement and drainage. The cosmetic results were satisfactory.One-staged correction of alveolar cleft and the lip and nasal deformities secondary to lip cleft can achieve good results.

Lane detection is one of fundamental but critical problems for lane following system of Intelligent Vehicles. However, a robust and cost effective approach is still a deserve exploit issue. A novel and effective approach using a five steps scheme is presents. First, Canny detector is used to obtain edge map from the road image acquired from monocular camera mount on vehicle; Second, a matching process is conducted to normalize the potential candidates of road line or boundary; Third, a searching procession is utilized for reinforce potential road lines while degraded those impossible ones; Forth, a linking condition is investigated to further enhance the confidence of the potential lane lines; Finally, a K-means cluster based algorithm is employed to localize the lane lines, in this step, false edges will be rejection and only optimal lines will be accepted. Experimental results show that the proposed approach can achieve robust and effective localize the lane line in various bad road scenes, and has a better generalize capability with road types.

Object tracking using vision technology is one of the important and complex functions in computer vision. It should become more challenge in case of there are partial occlusions and significant clutter. A mean shift procedure embedded approach for vehicle and pedestrian tracking under real road scenes is presents. A combined hue and saturation of HSI color model and local orientation information are extracted and constructed to represent the target features since it is more robust to illumination than only RGB color space. The mean shift procedure is employed to fast searching the mode of the potential object in a neighborhood of current video sequence.Meanwhile, a global motion compensation is considered for improve the robust and real-time of the tracking procedure.Some examples are investigated and used to evaluate the proposed approach. Experimental results demonstrate that the proposed approach is robust and validate in complicated real scenes.

To study the conditions and parameters of purifying 2,3,5,4'-tetrahydroxy-stilbene-2-O-beta-D-glycoside from Polygonum multiflori.Absorption capacity of four resins for 2,3,5,4'-tetrahydroxy-stilbene-2-O-beta-D-glycoside was compared. With the adsorption ability as indexes, the process of absorbing and purifying 2,3,5,4'-tetrahydroxy-stilbene-2-O-beta-D-glycoside from P. multiflori with S-8 macroporous resin absorbent was selected by orthogonal design.The S-8 resin was the best of the four resins. The optimum process condition was 50% ethanol as eluting solvent, the flow rate at 1.5 mL x min(-1), pH at 7-8, and the solution concentration at 0.2 g x mL(-1). The absorption capacity by this process was 36.89 mg x g(-1).The process is simple and convenient and the regeneration of resin is easy, so this method of purification is advisable.

The remote fault diagnosis for complex equipment based on virtual instrument (VI) technology is studied. It can promote the maintenance and fault diagnosis methods under the network environment. Firstly, the technology necessity of remote fault diagnosis for complex equipment is analyzed. Secondly, the system model of remote fault diagnosis system including base station and center station is discussed. Then the versatile Computer Supported Cooperate Work (CSCW) environments for remote fault diagnosis are developed, which are based on LabWindows/CVI and Datasocket technology of National Instrument respectively. LabWindows/CVI is adopted to set up the VI environment, which support DataSocket transmission protocol for communication between base station and center station. Finally, a test system is setup to validate the proposed system model. An engine is taken as an example to establish remote fault diagnosis system. Several key technology designs are discussed. It is proved to be efficient, and the design scheme of remote fault diagnosis is feasible.

To investigate whether TRAIL can synergize with adriamycin (ADM) to kill osteosarcoma cells (U2OS) in vitro, and its possible molecular mechanism.MTT was used to evaluate the cytotoxic effect of TRAIL and ADM either used alone or in combination at 24 hours after treatment to U20S cells. Cell apoptosis and its proportion were detected by flow cytometry assay. Acridine orange fluorescence microscopy and transmission electron microscopy were used to examine cellular and ultrastructural changes of apoptosis. The changes of cFLIP in mRNA and protein level were semi-quantified by RT-PCR and Western blot analysis.(1) U2OS cells were not sensitive to TRAIL (IC(50)1 mg/L); the cells were relatively more responsive to ADM in an apparent dose-effect fashion. (2) The combination of TRAIL and ADM presented a synergistic effect on U2OS cells. Subtoxic concentration of TRAIL (0.1 mg/L) combined with subtoxic concentration of ADM (1.0 micromol/l) killed (49.54 +/- 2.79)% of U2OS cells. (3) The cytotoxicity was mainly attributed to cell apoptosis as demonstrated by flow cytometry assay, fluorescence microscopy and electron microscopy.Subtoxic dose of TRAIL can effectively kill osteosarcoma cells (U2OS) in combination with subtoxic dose of ADM, but not effective when used alone. Apoptosis is the main mechanism of this killing effect induced by combination of TRAIL and ADM. Down regulation of cFLIP at mRNA and protein level is involved in this apoptosis pathway.

A method investigating a Gaussian radial-basis-function neural network (GRBFNN) with sliding mode control (SMC) for missile electrohydraulic servo mechanism is presented. Since the dynamics of the system are highly nonlinear and have large extent of model uncertainties, such as big changes in parameters and external disturbance, firstly, SMC is introduced. Since the accurate equivalent control is difficult to reach, a Gaussian radial basis function neural network is utilized. By adjusting the weight on-line, a neural-network-based SMC is developed to estimate the equivalent control of SMC control system. Then the switching control is appended to guarantee the stability of the proposed controller, and a set of fuzzy control rules are used to attenuate chattering phenomenon of the switching control. We apply the control method to the missile electro-hydraulic servo mechanism. Simulation results verify the validity of the proposed approach.

A new learning algorithm for fuzzy system to approximate unknown nonlinear continuous functions is presented. Fast terminal sliding mode combining the finite time convergent property of terminal attractor and exponential convergent property of linear system is introduced into the conventional back-propagation learning algorithm to improve approximation ability. The Lyapunov stability analysis guarantees that the approximation is stable and converges to the unknown function with improved speed. The proposed fuzzy approximator is then applied in the control of an unstable nonlinear system. Simulation results demonstrate that the proposed method is better than conventional method in approximation and tracing control of nonlinear dynamic system.

To investigate the effects of recombinant AZURIN protein of P. aeruginosa on growth and apoptosis of U2OS cells.The AZURIN gene was amplified from the genome of P.aeruginosa by PCR, and cloned into prokaryotic expression vector pQE30. The soluble AZURIN protein was expressed in E. coli cells M15, then purified and refolded. After treatment of AZURIN, the cell cycle, proliferation and apoptosis were determined by morphological observation, MTT assay, flow cytometry(FCM) and DNA fragmentation assay. Mitochondrial membrane potential(DeltaPsim) was measured by FCM.The purity of recombinant protein AZURIN reached to 99.1%. Proliferation of U2OS cells were significantly inhibited 12 h after AZURIN (100-200 mg/L) treatment. Apoptosis peak and DNA ladder were observed. Mitochondrial membrane potential decreased gradually from 12 h to 72 h after AZURIN treatment.The recombinant AZURIN inhibit the growth of the human osteosarcoma U2OS cells and inducs apoptosis in vitroìwhich may be associated with the decrease of mitochondrial membrane potential.

Bacterial redox protein azurin can selectively inhibit proliferation, and induce apoptosis in various human cancer cells. These in vitro findings have been confirmed in vivo in nude mice bearing tumor xenograft. Furthermore, azurin could diminish tumor volume in nude mice bearing tumor xenograft with no evidence of toxicity. The mechanism of its action is unknown. This study was designed to explore the effects of azurin on apoptosis of osteosarcoma cell line U2OS, and its molecular mechanism.U2OS cells were cultured with different concentrations of azurin. Cell viability was detected by MTT assay. The 50% inhibitory concentration (IC(50)) of azurin was calculated by Bliss method. Apoptotic morphology and apoptotic body of U2OS cells were observed under fluorescent microscope, and transmission electron microscope. DNA ladder was observed through agarose gel electrophoresis. Cell apoptosis was determined by flow cytometry (FCM). Protein levels of Bax, Bcl-2, and Caspase-3 were quantified by Western blot.Azurin inhibited growth and induced apoptosis of U2OS cells in a dose-dependent manner 48 h after treatment, with the IC(50) of(114.54+/-7.65) mg/L. Moreover, its inhibitory effect was significantly higher on U2OS cells than on MG63 cells or L-02 cells under the same concentrations (P0.05). When treated with 100 or 200 mg/L of azurin for 24 h, U2OS cells showed typical apoptotic morphology, typical DNA ladder bands were observed. No apoptotic feature was observed in control cells. Sub-G1 peak and apoptotic peak of U2OS cells were observed when exposed to 200 mg/L of azurin for 48 h with the apoptosis index of 35.8%, cell cycle was arrested in G1 phase. Bcl-2 was down-regulated when U2OS cells were treated with azurin for 24 h, while Bax and caspase-3 were up-regulated.Azurin could selectively induce apoptosis of human osteosarcoma U2OS cells. The induction of apoptosis by azurin may be closely associated with down-regulation of Bcl-2, up-regulation of Bax, and activation of Caspase-3.

As a low molecular weight redox protein elaborated from the pathogenic bacteria Pseudomonas aeruginosa, azurin is one of representative bacterial products applied in the treatment of tumour. We found that the growth of U2OS cells was significantly inhibited by azurin in a dose-dependent manner with the IC(50) value of 114.54+/-7.65 mgl(-1). But the growth of MG63 cells or L02 cells was almost not inhibited by azurin (P

To establish the HPLC fingerprint of Xuelian injection.HPLC with Diamonsil C18 (4.6 mm x 250 mm, 5 microm) column was used, the methanol-1% acetic acid as a mobile phase and detection wavelength at 270 nm.Indicating 11 peaks on HPLC fingerprint.This method is simple and acurate with a good reproducibility and can be used as a quality control method for Xuelian injection.

The matching similarity measures that can be used in image target recognition are surveyed and a novel similarity measure is proposed in this paper. Two basic factors that affect the image matching performance and the merits and faults of two common types of image matching algorithm are firstly analyzed. Then, based on the systematic study of similarity measures, image matching projection similarity measure is defined by simplify the classical normalized correlation measure. An example of the application of the proposed matching similarity measure in image target recognition and position is given at the end of this paper; the experimental results show its feasibility and effectivity.

To explore the relationship between paraoxonase-1 (PON1) gene Gln192Arg polymorphism and sporadic Alzheimer's disease (AD) in Chinese.A total of 165 AD patients and 174 age-matched control subjects were enrolled in this study for examination of PON1 Gln192Arg and apolipoprotein E gene polymorphisms using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).The distribution of PON1 allelic and genotypic frequencies did not significantly differ between AD patients and the control subjects, even after the stratification by ApoE-epsilon4 status.Gln192Arg polymorphism of the PON1 gene is not associated with sporadic AD in Chinese.

To study the immunophenotyping of adult patients with acute leukemia and its association with the prognosis.Immunophenotyping was performed in 106 adult patients with acute leukemia by three-color flow cytometry analysis using CD34/SSC gating.The antigens expressed in 71 patients with acute myeloid leukemia (AML) were mainly CD13, CD33, HLA-DR, CD34 and CD117. Lymphoid antigen expression was identified in 23.9% adult AML patients and CD56 antigen expression in 15.5% of the AML patients. In 29 patients with acute lymphoblastic leukemia (ALL), the expressed antigens were mainly HLA-DR, CD10, CD19, CD34 and CD7, and 34.5% of these patients were found to be positive for myeloid antigen expression. Complete remission (CR) rate in AML patients with lymphoid antigen expression after chemotherapy was lower than that in AML patients without lymphoid antigen expression (52.9% vs 77.8%, P0.05), and no significant impact was noted of myeloid antigen expression in ALL on the CR of the patients (70.0% vs 94.7%, P0.05). The CR rate in AML with CD56 antigen expression was lower than that in AML without CD56 expression (36.4% vs 78.3%, P0.025), and the CR rate in CD34+ AML was lower than that in CD34- AML (56.0% vs 80.4%, P0.05).Gating of CD45/SSC can eliminate the interference of normal cells to render more reliable immunophenotyping results. The expressions of CD56+, CD34+, lymphoid antigen in adult AML patients, who have lower CR rate, often signify poor prognosis.

In recognition of the ever increasing problems that manual test approaches bring, an intelligent automatic test and diagnostic system (IATDS) is being developed which is described in the paper. The system performs a functional test to electronic equipment systems under test and provides the operator with a fault diagnostic approach which combines expert system (ES) techniques and guided-probe fault detection and isolation techniques. The major objectives of the system is to decrease test time, to improve diagnostic capabilities and supply guidance to maintenance personnel. >

Disrupted white matter integrity and abnormal cortical thickness are widely reported in the pathophysiology of obsessive-compulsive disorder (OCD). However, the relationship between alterations in white matter connectivity and cortical thickness in OCD is unclear. In addition, the heritability of this relationship is poorly understood. To investigate the relationship of white matter microstructure with cortical thickness, we measure fractional anisotropy (FA) of white matter in 30 OCD patients, 19 unaffected siblings and 30 matched healthy controls. Then, we take those regions of significantly altered FA in OCD patients compared with healthy controls to perform fiber tracking. Next, we calculate the fiber quantity in the same tracts. Lastly, we compare cortical thickness in the target regions of those tracts. Patients with OCD exhibited decreased FA in cingulum, arcuate fibers near the superior parietal lobule, inferior longitudinal fasciculus near the right superior temporal gyrus and uncinate fasciculus. Siblings showed reduced FA in arcuate fibers near the superior parietal lobule and anterior limb of internal capsule. Significant reductions in both fiber quantities and cortical thickness in OCD patients and their unaffected siblings were also observed in the projected brain areas when using the arcuate fibers near the left superior parietal lobule as the starting points. Reduced FA in the left superior parietal lobule was observed not only in patients with OCD but also in their unaffected siblings. Originated from the superior parietal lobule, the number of fibers was also found to be decreased and the corresponding cortical regions were thinner relative to controls. The linkage between disrupted white matter integrity and the abnormal cortical thickness may be a vulnerability marker for OCD.

Analyzing the image geometrical distortion error with mathematical model and its effect on image matching registration. Researching two geometrical correction methods: perspective transformation and affine transformation. Presenting the method of estimating geometrical distortion parameters with the two transformations and the geometrical correction method of distorted image with the estimated parameters. The experiment shows the two methods are practical to image matching. Besides, paper presents some geometrical correction principles.

The problem of Map-matching is one key problem in the field of aircraft and vehicle guidance. It deals with the technologies of remote sensing, computer vision, image processing and pattern recognition, etc. Researchers are focusing on how to improve the system's performance, to reduce the searching times and error matching probability. With using an improved quadtree image representative method and the idea of the sequential similarity detection algorithm (SSDA), a hierarchical map-matching algorithm based on embedded MPP system is designed in this paper. The algorithm can greatly reduce matching times and improve locate accuracy.

Wavelet transform is a new and good image processing method that well separates different frequency components of an image. This paper mainly discuses image edge detection with the band-pass filtering property of wavelet transformation. After wavelet transforming and edge extracting, an image can be clearly seen in detail. Compared with other image edge extraction methods, such as Roberts operator, Laplacian operator, Sobel operator and Kirsch operator, this method has good extraction effect and is suitable to binary process. This is very useful to medical diagnose and remote sense image recognition.