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The article discusses the incidence and nature of the male genital exposure behavior as reported by college women. The DMS III-R defines exhibitionism as "recurrent, intense sexual urges and sexually arousing fantasies of at least six months duration involving the exposure of one's genitals to a stranger." There are two available databases concerning exhibitionism: records of legal and mental health sources and surveys of female victims. The former indicates that exhibitionists' account for approximately 30% of the paraphilias involved in the legal systems of the U.S., Great Britain, and Canada. Exhibitionism is of ten viewed as a victimless nuisance as suggested in the title "Sexual Abnormalities: Harmless Varieties." The data confirm this view for the majority of exposure events. However, a small percentage of women did rate the experience as severely distressing and severely affecting their attitudes toward men and/or sex or toward themselves as women. Researchers reported that 11% of their victim sample found the experience extremely upsetting. These small percentages however, translate into millions of women. The current methodology is inadequate to assess the ramifications of such experiences, which would be better addressed by intensive individual interviewing. These findings also suggest that the true incidence of exhibitionism is underestimated by police reports.

Attention-Deficit/Hyperactivity Disorder (ADHD) is reported to have an incidence of 3–5%, and is associated with a variety of interpersonal, academic, and social problem behaviors. There is controversy as to whether ADHD is a learned behavioral or brain dysfunction. Research has explored a variety of measures to assess behavioral and brain dysfunctions in this population, with no consistent and clearly diagnostic results. We investigated whether a new psychometric and a new electroencephalographic procedure would clearly differentiate ADHD. The psychometric was based on DSM-IV criteria and the EEG measure was based on the assumption that ADHD interferes with cognitive transition from one discrete task to another. Parents of four ADHD boys (ages 8–12) and four age- and interest-matched non-ADHD boys completed the ADHD Symptom Inventory, while their sons' EEG was monitored during viewing of a video and reading of a book. For the ADHD boys, this was repeated a second time, 3 months later, to assess test-retest reliability. Both the psychometric and the EEG measures clearly differentiated the two samples (p's < .01) with no overlap in scores, were reliable over 3 months (r = .87), and were significantly correlated with one another (r = .85). While a small sample size, these robust, related and reliable findings suggest that both the psychometric and the psychophysiological EEG measures deserve further replication and exploration. [ABSTRACT FROM AUTHOR]

This study examines the behavioral responses of IDDM patients to per ceived hypoglycemic symptoms. To determine whether or not patients used reflectance meters to confirm low blood glu cose (BG) levels before self-treatment, a survey was administered that asked participants to report their hypoglycemic symptoms, their confidence in ability to recognize hypogly cemia, and their first four actions after perceiving hypoglycemic symptoms. Of 79 respondents, the majority reported not using self-measurement to confirm low BG levels before taking action to raise those levels. Patients who reported more symp toms were more confident in their ability to recognize low BG levels. [ABSTRACT FROM PUBLISHER]

Opinion. Provides information on an individual's experience while traveling Kodiak Island. Description of the Afognak Island; Estimated number of bears found on the island; Information on Kodiak archipelago. INSET: Time and place.

The synthesis of large numbers of diverse molecular scaffolds with controlled molecular properties is a significant challenge in synthetic organic chemistry. A modular unified synthesis was developed, and was exploited in the synthesis of sixteen diverse three-dimensional scaffolds. The approach exploited two cyclisation precursors to be converted, using a toolkit of cyclisation reactions, into spirocyclic and fused-ring scaffolds. Remarkably, Pd-catalysed aminoarylation of substituted N -Boc-hex-5-enylamine cyclisation precursors to yield N- Boc piperidine-containing scaffolds was successful which was ascribed to a significant Thorpe−Ingold effect. Computational property analysis showed that the decorated scaffolds are shape-diverse, and enable diverse lead-like chemical space to be targeted. Image 1 • Unified synthesis of diverse building blocks. • Pd-catalysed aminoarylation yields N- Boc piperidine-containing scaffolds. • The decorated scaffolds are shape-diverse, and enable diverse lead-like chemical space to be targeted. [ABSTRACT FROM AUTHOR]

The article focuses on the results of correlation analyses of blood glucose rate of change (BGRATE) with symptoms from a pilot investigation designed to evaluate whether improvements in glycemic control seen with basal plus prandial insulin analog regimens compared with basal insulin analog in patients with type 2 diabetes would lead to measurable mood and cognitive differences. It mentions that there were no significant differences seen for mood or cognitive symptoms between insulin regimens.

A correction to the article "Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET" by Kaihang Wang, Amit Sachdeva, Daniel J. Cox and colleagues is presented.