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303 results on '"Bellone, M."'

301. Methisoprinol effect on enriched B and T lymphocyte populations stimulated with phytohemagglutinin.

Author

Pasino M, Bellone M, Cornaglia Ferraris P, Tonini GP, and Massimo L

Subjects
Adult, Cell Division drug effects, Dose-Response Relationship, Drug, Humans, Rosette Formation, B-Lymphocytes drug effects, Inosine analogs & derivatives, Inosine Pranobex pharmacology, Lymphocyte Activation drug effects, Phytohemagglutinins pharmacology, T-Lymphocytes drug effects
Abstract

The Authors investigated the effect of methisoprinol on separated B and T lymphocytes from 8 healthy donors. B or T treated cells, recombined with T or B untreated cells, were subsequently mitogen stimulated. Proliferative response resulted significantly increased, in comparison to a control, when T lymphocytes were preincubated with the drug, while treating only B lymphocytes led to a decrement. These data confirm the hypothesis of a direct action of the drug on T lymphocytes, but are also consistent with its influence on B cells too, even though with an opposite effect.

Published
1981

303. [Hemorrhage caused by erosions and gastric stress ulcers. Surgical problems].

Author

Samori G, Ferrandi A, Gherardi G, Bellone M, and Calzoni D

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Female, Gastrointestinal Hemorrhage etiology, Gastrointestinal Hemorrhage therapy, Humans, Male, Middle Aged, Stomach Ulcer complications, Gastrointestinal Hemorrhage surgery, Stomach Ulcer surgery, Stress, Physiological complications
Published
1987

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