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613 results on '"Androstanes metabolism"'

301. Steroids of invertebrates. VI. Effect of tentacular homogenates in vitro upon post-androstenedione metabolism in the male phase of Ariolimax californicus ovotestis.

Author

Gottfried H and Dorfman RI

Subjects
Androstanes biosynthesis, Animals, In Vitro Techniques, Male, Neurosecretory Systems enzymology, Sterols biosynthesis, Tritium, 17-Ketosteroids metabolism, Androstanes metabolism, Gonads metabolism, Neurosecretory Systems metabolism, Snails metabolism
Published
1970
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302. Conversion of cholesterol to testosterone and androstanediol in testicular homogenates of immature and mature rats.

Author

Strickland AL, Nayfeh SN, and French FS

Subjects
17-Hydroxycorticosteroids isolation & purification, 17-Hydroxycorticosteroids metabolism, Androstanes isolation & purification, Androsterone analysis, Animals, Chromatography, Thin Layer, Male, Oxidoreductases metabolism, Rats, Sterols isolation & purification, Sterols metabolism, Testis enzymology, Testosterone isolation & purification, Tritium, Aging, Androstanes metabolism, Cholesterol metabolism, Testis metabolism, Testosterone metabolism
Published
1970
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303. In vitro and in vivo studies on the functional significance of androgen receptors in rat prostate.

Author

Rennie P and Bruchovsky N

Subjects
17-Hydroxycorticosteroids metabolism, Ammonium Sulfate, Androstanes metabolism, Animals, Biological Transport, Carrier Proteins isolation & purification, Castration, Cell Nucleus metabolism, Chemical Precipitation, Chromatography, Gel, Chromatography, Ion Exchange, Cytoplasm metabolism, Kinetics, Male, Prostate cytology, Rats, Tritium, Dihydrotestosterone metabolism, Prostate metabolism, Receptors, Drug, Testosterone metabolism
Published
1972

304. Studies on an extract of rat testicular microsomal fraction that catalyses the transformation of progesterone into 17-hydroxyprogesterone and androgens.

Author

Ford HC and O'Donnell VJ

Subjects
Androstanes metabolism, Animals, Chromatography, Cytochromes analysis, Freeze Drying, In Vitro Techniques, Iron analysis, Ketones metabolism, Male, Mixed Function Oxygenases metabolism, Oxidoreductases analysis, Proteins analysis, Rats, Surface-Active Agents, Testosterone biosynthesis, Ultracentrifugation, Androgens biosynthesis, Hydroxyprogesterones biosynthesis, Microsomes enzymology, Progesterone metabolism, Testis enzymology
Abstract

The supernatant obtained by centrifugation of Triton N-101-treated freeze-dried rat testicular microsomal fraction at 105000g(av.) for 2h transformed progesterone into testosterone via 17-hydroxypregn-4-ene-3,20-dione and androst-4-ene-3,17-dione. Hydroxylation at C-17 of 3beta-hydroxypregn-5-en-20-one and deoxycorticosterone was not observed. Non-haem iron protein, cytochrome P-450 and material with NADPH dehydrogenase activity were precipitated by 40% saturation of the supernatant with ammonium sulphate; however, it was not possible to establish the participation of these substances in the 17alpha-hydroxylase and side-chain-cleavage activities also present in the precipitate. The results of gel-filtration chromatography indicated that the Triton N-101 extract consisted primarily of a suspension of small particles of microsomes and that the progesterone 17-hydroxylase and the 17-hydroxypregn-4-ene-3,20-dione side-chain-cleavage enzyme were not in true solution.

Published
1971
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305. Testosterone metabolism by mouse placenta in vitro.

Author

Rembiesa R, Marchut M, and Warchol A

Subjects
17-Ketosteroids metabolism, Androstanes metabolism, Animals, Carbon Isotopes, Chromatography, Paper, Female, In Vitro Techniques, Mice, Mice, Inbred Strains, Oxidation-Reduction, Pregnancy, Placenta metabolism, Testosterone metabolism
Published
1971
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307. Formation and metabolism of testosterone in rat skin.

Author

Flamigni CA, Collins WP, Koullapis EN, and Sommerville IF

Subjects
Animals, Back, Carbon Isotopes, Chromatography, Thin Layer, Female, In Vitro Techniques, Male, Rats, Scrotum, Vulva, 17-Ketosteroids biosynthesis, 17-Ketosteroids metabolism, Androstanes biosynthesis, Androstanes metabolism, Dehydroepiandrosterone metabolism, Hydroxyprogesterones metabolism, Pregnanes biosynthesis, Pregnenolone metabolism, Progesterone metabolism, Skin metabolism, Testosterone biosynthesis, Testosterone metabolism
Published
1970
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308. The metabolism of testosterone by skin in normal subjects and in testicular feminization.

Author

Jenkins JS and Ash S

Subjects
17-Ketosteroids metabolism, Adult, Aged, Androstanes metabolism, Androsterone metabolism, Autoradiography, Carbon Isotopes, Chromatography, Gas, Chromatography, Thin Layer, Female, Humans, Hydrocortisone metabolism, In Vitro Techniques, Male, Middle Aged, Androgen-Insensitivity Syndrome metabolism, Skin metabolism, Testosterone metabolism
Published
1971
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309. Evidence for the presence of 17 beta-hydroxysteroid oxido-reductase and 19-hydroxylase systems in domestic duck (Anas platyrhynchos) adrenal mitochondria.

Author

Mehdi AZ and Sandor T

Subjects
17-Hydroxycorticosteroids metabolism, Adrenal Glands cytology, Androstanes metabolism, Animals, Carbon Isotopes, Chromatography, Paper, Chromatography, Thin Layer, Crystallization, Desoxycorticosterone metabolism, Ducks, Male, NADP biosynthesis, Radioisotope Dilution Technique, Testosterone biosynthesis, Testosterone metabolism, Tritium, Adrenal Glands enzymology, Hydroxysteroid Dehydrogenases metabolism, Mitochondria enzymology, Mixed Function Oxygenases metabolism
Published
1971
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310. Effect of phenobarbital on the conversion of cholesterol to taurocholic acid. Bile acids and steroids 204.

Author

Einarsson K and Johansson G

Subjects
17-Hydroxycorticosteroids metabolism, Aminopyrine metabolism, Androstanes metabolism, Animals, Carbon Isotopes, Chromatography, Paper, Chromatography, Thin Layer, Liver drug effects, Male, Rats, Sterols metabolism, Tritium, Bile Acids and Salts biosynthesis, Cholesterol metabolism, Liver metabolism, Phenobarbital pharmacology
Published
1968
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312. Regulatory interactions of dehydroepiandrosterone and its sulfate in rat testis tissue.

Author

Notation AD and Ungar F

Subjects
17-Ketosteroids metabolism, Androstanes metabolism, Animals, Carbon Isotopes, Chorionic Gonadotropin, Chromatography, Chromatography, Thin Layer, Dehydroepiandrosterone metabolism, Depression, Chemical, Esters metabolism, Estrogens, Conjugated (USP) metabolism, Humans, Male, Quaternary Ammonium Compounds, Rats, Testosterone pharmacology, Tritium, Dehydroepiandrosterone pharmacology, Sulfates metabolism, Testis metabolism
Published
1968
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313. Secretion of free and sulfate-conjugated neutral steroids by the human testis. Effect of administration of human chorionic gonadotropin.

Author

Laatikainen T, Laitinen EA, and Vihko R

Subjects
17-alpha-Hydroxypregnenolone metabolism, Adult, Chromatography, Gas, Hernia, Inguinal, Humans, Hydroxyprogesterones metabolism, Male, Middle Aged, Oximes, Pregnenolone metabolism, Silicones, Spectrum Analysis, Sterols metabolism, Stimulation, Chemical, Testis blood supply, Testis drug effects, Veins, 17-Hydroxycorticosteroids metabolism, Androstanes metabolism, Chorionic Gonadotropin pharmacology, Pregnanes metabolism, Sulfates metabolism, Testis metabolism
Published
1971
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314. [Characterization of the enzyme system for transfer of hydrogen from estradiol-17-beta to androgens in rat liver microsomes and cytoplasm].

Author

Wenzel M and Wolf S

Subjects
Animals, Cytoplasm, Female, Hydrogen-Ion Concentration, Kinetics, Liver enzymology, NAD metabolism, NADP metabolism, Rats, Tritium, 17-Ketosteroids metabolism, Androstanes metabolism, Estradiol metabolism, Hydrogen metabolism, Hydroxysteroid Dehydrogenases metabolism, Liver metabolism, Microsomes, Liver metabolism
Published
1969

318. [Modus of hormonal excretion and hormonal effects of 1-alpha-methyl-5-alpha-androsten-17-beta-ol-3-on (mesterolon in women)].

Author

Abrahamsson L, Haagenrud A, Hackl H, Haglund V, and Wassén A

Subjects
Adult, Androstanes metabolism, Estradiol urine, Estriol urine, Estrone urine, Female, Follicle Stimulating Hormone urine, Humans, Ketones metabolism, Luteinizing Hormone urine, Male, Menstruation drug effects, Methylation, Middle Aged, Pregnanediol urine, Pregnanetriol urine, Uterus drug effects, 17-Ketosteroids urine, Androstanes pharmacology, Androsterone urine, Estrogens urine, Gonadotropins, Pituitary urine, Ketones pharmacology
Published
1973
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319. The in vivo metabolism of 16 alpha-hydroxylated C19 steroids in late pregnancy.

Author

YoungLai EV and Solomon S

Subjects
17-Ketosteroids urine, Androgens urine, Androstanes urine, Carbon Isotopes, Etiocholanolone urine, Female, Humans, Hydroxides, Injections, Intravenous, Male, Models, Biological, Pregnancy, Sex Factors, Sulfates, Time Factors, Tritium, Uronic Acids, 17-Ketosteroids metabolism, Androgens metabolism, Androstanes metabolism, Estriol urine, Estrone urine
Published
1968
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320. Biosynthesis and secretion of steroids by the canine testis.

Author

van der Molen HJ and Eik-Nes KB

Subjects
17-Ketosteroids metabolism, 17-alpha-Hydroxypregnenolone metabolism, Androstanes metabolism, Animals, Carbon Isotopes, Chorionic Gonadotropin pharmacology, Cyclic AMP pharmacology, Dehydroepiandrosterone metabolism, Dogs, Humans, Hydroxyprogesterones metabolism, Male, Progesterone metabolism, Testis drug effects, Testosterone metabolism, Tritium, Pregnenolone metabolism, Steroids biosynthesis, Steroids metabolism, Testis metabolism, Testosterone biosynthesis
Published
1971
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327. Pathways for androgen biosynthesis in monkey testis.

Author

Hoschoian JC and Brownie AC

Subjects
17-alpha-Hydroxypregnenolone metabolism, Androstanes metabolism, Animals, Carbon Isotopes, Chemical Phenomena, Chemistry, Chromatography, Paper, Chromatography, Thin Layer, Dehydroepiandrosterone metabolism, Haplorhini, Hydroxyprogesterones metabolism, Male, Pregnenolone metabolism, Progesterone metabolism, Tritium, Testis metabolism, Testosterone biosynthesis
Published
1967
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328. [Influence of human placental lactogen (HPL) on human placental estrogen formation].

Author

Tominaga S

Subjects
Androstanes metabolism, Carbon Isotopes, Chorionic Gonadotropin pharmacology, Chromatography, Thin Layer, Dehydroepiandrosterone metabolism, Female, Humans, In Vitro Techniques, Placenta drug effects, Placental Lactogen pharmacology, Pregnancy, Tritium, Estrogens biosynthesis, Placenta metabolism, Placental Hormones pharmacology
Published
1971

329. In vitro measurements in human placenta and fetal membranes of rates of entry, metabolism and release of steroids.

Author

Tseng L, Stolee A, and Gurpide E

Subjects
17-Ketosteroids metabolism, Amnion metabolism, Androstanes metabolism, Carbon Isotopes, Cell Membrane Permeability, Estrogens, Extraembryonic Membranes enzymology, Female, Humans, Hydroxysteroid Dehydrogenases metabolism, In Vitro Techniques, Oxidoreductases metabolism, Placenta enzymology, Pregnancy, Sulfatases metabolism, Testosterone metabolism, Tritium, Estradiol metabolism, Estrone metabolism, Extraembryonic Membranes metabolism, Placenta metabolism, Pregnanes metabolism, Progesterone metabolism, Progestins metabolism
Published
1972
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330. [Dependence of hydrogen transfer between estradiol-17 and 4-androstene-3,17-dione in microsomal fraction of rat liver and ovaries on thyroid gland].

Author

Pollow K, Sokolowski G, and Pollow B

Subjects
Animals, Female, Hydrogen metabolism, Hyperthyroidism enzymology, Hypothyroidism enzymology, Ketosteroids metabolism, Ovary cytology, Rats, Rats, Inbred Strains, Sterols, Testosterone, Thyroid Gland physiopathology, Transferases metabolism, 17-Ketosteroids metabolism, Androstanes metabolism, Estradiol metabolism, Microsomes enzymology, Microsomes, Liver enzymology, Thyroid Gland physiology
Published
1972

331. Studies on the aromatisation of neutral steroids in pregnant women. 8. Metabolism of 5-androstene-3 beta, 16 alpha, 17 beta-triol and 5-androstene-3 beta, 16 beta, 17 beta-triol at midgestation, following the perfusion of placentas in situ.

Author

Vokal H, Archer DF, Wiqvist N, and Diczfalusy E

Subjects
Androstenols biosynthesis, Androstenols metabolism, Carbon Isotopes, Estriol urine, Female, Gestational Age, Humans, Perfusion, Placenta analysis, Tritium, Androstanes metabolism, Placenta metabolism, Pregnancy
Published
1970

332. Studies on the dynamics of plasma androgens and on the origin of dihydrotestosterone in dogs.

Author

Tremblay RR, Forest MG, Shalf J, Martel JG, Kowarski A, and Migeon CJ

Subjects
17-Ketosteroids blood, Adrenal Glands metabolism, Androstanes blood, Animals, Carbon Isotopes, Chromatography, Paper, Chromatography, Thin Layer, Dogs, Male, Metabolic Clearance Rate, Methods, Testis metabolism, Testosterone blood, Tritium, 17-Ketosteroids metabolism, Androstanes metabolism, Dihydrotestosterone biosynthesis, Testosterone metabolism
Published
1972
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335. Inhibition of steroid 3-sulfatase by endogenous steroids. A possible mechanism controlling placental estrogen synthesis from conjugated precursors.

Author

Townsley JD, Scheel DA, and Rubin EJ

Subjects
17-Hydroxycorticosteroids blood, Androstanes blood, Carbon Isotopes, Chromatography, Paper, Chromatography, Thin Layer, Dehydroepiandrosterone blood, Endoplasmic Reticulum enzymology, Estriol blood, Feedback, Female, Humans, Hydroxysteroid Dehydrogenases analysis, In Vitro Techniques, Isomerases analysis, NAD metabolism, Placenta enzymology, Pregnancy, Pregnenolone blood, Pregnenolone metabolism, Progesterone biosynthesis, Progesterone blood, Sterols blood, Sulfates blood, Tritium, 17-Ketosteroids metabolism, Androstanes metabolism, Dehydroepiandrosterone metabolism, Estrogens biosynthesis, Placenta metabolism, Sulfatases antagonists & inhibitors
Published
1970
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336. Excretion of steroid hormones in adults. C19 and C21 steroids in faeces from pregnant women.

Author

Eriksson H, Gustafsson JA, and Sjövall J

Subjects
Adult, Bacteria enzymology, Carbon Isotopes, Chromatography, Gas, Chromatography, Gel, Dextrans, Feces analysis, Female, Glucuronidase, Humans, Hydrolases, Intestines microbiology, Oxidoreductases, Pregnancy, Spectrum Analysis, Stereoisomerism, Steroids analysis, Steroids isolation & purification, Sulfatases, Sulfuric Acids metabolism, Androstanes metabolism, Pregnanediol metabolism, Pregnanes metabolism, Pregnanetriol metabolism, Steroids metabolism
Published
1970
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337. The in vitro utulization of (4-14C)-dehydroisoandrosterone by human adrenocortical tumors associated with virilism.

Author

Neville AM, Webb JL, and Symington T

Subjects
17-Ketosteroids metabolism, Adenoma enzymology, Adolescent, Adrenal Gland Neoplasms enzymology, Androstanes metabolism, Carbon Isotopes, Child, Chromatography, Humans, Hydroxysteroid Dehydrogenases metabolism, In Vitro Techniques, Isomerases metabolism, Male, Spectrophotometry, Sterols metabolism, Ultraviolet Rays, Virilism enzymology, Adenoma metabolism, Adrenal Gland Neoplasms metabolism, Dehydroepiandrosterone metabolism, Virilism metabolism
Published
1969
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338. A time-based study of the in vitro metabolism of [4-14C]-androstenedione and [1,2-3H2]epitestosterone by sheep placental tissue.

Author

Harvey G, Pierrepoint CG, Anderson AB, Turnbull AC, and Griffiths K

Subjects
Animals, Autoradiography, Carbon Isotopes, Culture Techniques, Estrone biosynthesis, Female, Pregnancy, Sheep metabolism, Time Factors, Tritium, 17-Ketosteroids metabolism, Androstanes metabolism, Placenta metabolism, Testosterone metabolism
Published
1972
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339. Induction of hepatic testosterone A-ring reductase by medroxyprogesterone acetate.

Author

Altman K, Gordon GG, Southren AL, Vittek J, and Wilker S

Subjects
17-Ketosteroids metabolism, Adrenal Glands physiology, Androstanes metabolism, Animals, Carbon Isotopes, Castration, Chromatography, Paper, Chromatography, Thin Layer, Dactinomycin pharmacology, Enzyme Induction, Fasting, Hydrocortisone pharmacology, Liver enzymology, Male, Medroxyprogesterone administration & dosage, Microsomes, Liver enzymology, Phenobarbital pharmacology, Progesterone pharmacology, Rats, Spectrophotometry, Testosterone metabolism, Time Factors, Medroxyprogesterone pharmacology, Oxidoreductases biosynthesis
Published
1972
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341. Combined ovarian and adrenal vein catheterization to determine the site(s) of androgen overproduction in hirsute women.

Author

Kirschner MA and Jacobs JB

Subjects
17-Ketosteroids blood, 17-Ketosteroids metabolism, Adrenal Glands metabolism, Adult, Androstanes blood, Androstanes metabolism, Clinical Trials as Topic, Collateral Circulation, Contraceptives, Oral pharmacology, Dexamethasone, Female, Humans, Metabolic Clearance Rate, Methods, Ovary metabolism, Pituitary Function Tests, Secretory Rate, Testosterone biosynthesis, Testosterone blood, Testosterone metabolism, Veins, Adrenal Glands blood supply, Androgens biosynthesis, Catheterization, Hirsutism metabolism, Ovary blood supply
Published
1971
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342. Influence of phenobarbital pretreatment on the in vitro ring A reduction of delta4-3-oxo-steroids in rat liver microsomes.

Author

von Bahr C, Lisboa BP, and Orrenius S

Subjects
Animals, Carbon Isotopes, Carbon Monoxide pharmacology, Chloromercuribenzoates pharmacology, Chromatography, Thin Layer, Cyanides pharmacology, Cytochromes pharmacology, In Vitro Techniques, Male, Microsomes, Liver drug effects, Microsomes, Liver enzymology, NADP metabolism, Rats, Stimulation, Chemical, 17-Ketosteroids metabolism, Androstanes metabolism, Microsomes, Liver metabolism, Mixed Function Oxygenases metabolism, Phenobarbital pharmacology
Published
1969
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343. Intranuclear metabolism of testosterone in kidneys of male and female rats.

Author

Verhoeven G and De Moor P

Subjects
Androstanes metabolism, Animals, Carbon Isotopes, Cell Nucleus enzymology, Chromatography, Paper, Chromatography, Thin Layer, Crystallization, Dihydrotestosterone biosynthesis, Dihydrotestosterone metabolism, Female, In Vitro Techniques, Kidney cytology, Kidney enzymology, Male, NADP metabolism, Oxidoreductases metabolism, Rats, Sterols metabolism, Tritium, Cell Nucleus metabolism, Kidney metabolism, Testosterone metabolism
Published
1971
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346. A rapid method for the measurement of androgen kinetics and conversion to estrogens using Sephadex LH-20 column chromatography.

Author

Olivo J, Vittek J, Southren AL, Gordon GG, and Rafii F

Subjects
17-Ketosteroids biosynthesis, Adult, Androstanes biosynthesis, Carbon Isotopes, Chromatography, Chromatography, Thin Layer, Crystallization, Dextrans, Estradiol biosynthesis, Estrone biosynthesis, Female, Humans, Kinetics, Male, Metabolic Clearance Rate, Methods, Testosterone biosynthesis, Tritium, 17-Ketosteroids metabolism, Androstanes metabolism, Testosterone metabolism
Published
1973
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347. Metabolism of C18 and C19 steroids by testis tissue.

Author

Lucis OJ and Lucis R

Subjects
17-Ketosteroids metabolism, Aged, Androstanes metabolism, Animals, Biotransformation, Carbon Isotopes, Chromatography, Paper, Chromatography, Thin Layer, Estrogens biosynthesis, Estrogens isolation & purification, Humans, In Vitro Techniques, Male, Rats, Estrone metabolism, Testis metabolism
Published
1969
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349. Urinary estrogen production rates in normal and endocrine-ablated subjects.

Author

Kirschner MA and Taylor JP

Subjects
17-Ketosteroids metabolism, Adrenalectomy, Adult, Age Factors, Androstanes metabolism, Carbon Isotopes, Castration, Chromatography, Gas, Estradiol metabolism, Estrone metabolism, Female, Fluoxymesterone pharmacology, Gynecomastia urine, Humans, Hypophysectomy, Male, Menopause, Menstruation, Methods, Middle Aged, Sex Factors, Tritium, Adrenal Glands physiology, Estradiol urine, Estrone urine, Ovary physiology, Pituitary Gland physiology
Published
1972
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350. Dissimilar isotopic ratios in urinary estrogens following simultaneous injection of delta-4-androstenedione-14C and estrone-6,7-3H.

Author

Kelly WG and Rizkallah TH

Subjects
17-Ketosteroids metabolism, Aged, Androstanes metabolism, Carbon Isotopes, Carcinoma metabolism, Choriocarcinoma metabolism, Endometrium, Estrone metabolism, Female, Humans, Middle Aged, Pregnancy, Tritium, Uterine Neoplasms metabolism, Estradiol urine, Estriol urine, Estrone urine
Published
1973
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