301. Severity, Risk Factors and Quality of Life of Patients associated with Chemotherapy-Induced Peripheral Neuropathy.
- Author
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Srivastava, Saumya P., Sinha, Aditi Prashant, Sharma, Kamlesh Kumari, and Malik, Prabhat Singh
- Subjects
HOSPITALS ,INFERENTIAL statistics ,PERIPHERAL neuropathy ,ADULT day care ,VEGETABLES ,CANCER chemotherapy ,CROSS-sectional method ,RESEARCH methodology ,TERTIARY care ,CLINICAL medicine research ,SEVERITY of illness index ,RISK assessment ,CONCEPTUAL structures ,QUALITY of life ,HOSPITAL wards ,BODY movement ,EXERCISE ,HEALTH behavior ,FRUIT ,DESCRIPTIVE statistics ,PACLITAXEL ,STATISTICAL sampling ,DATA analysis software ,DISEASE risk factors ,EVALUATION ,SYMPTOMS - Abstract
Chemotherapy-induced peripheral neuropathy (CIPN) refers to numbness, tingling, and burning sensation caused by chemotherapy that can cause impairment in Quality of Life (QoL) of the patients. Study assesses severity, risk factors, and quality of life of patients associated with CIPN. A cross sectional descriptive study was conducted at day care ward, tertiary care hospital India. Total of 98 patients receiving paclitaxel for ≥4 months were enrolled by convenient sampling. Data regarding demographics and clinical characteristics, CIPN severity, risk factors, and QoL were collected by structured questionnaires. Study revealed that median score of autonomic symptoms was higher than sensory and motor symptoms. Mean score of FACT/GOG-Ntx sub-domain was 99.05 ± 20.87on a scale of 0 to 152. ECOG Performance status, current exercise behavior, and fruit and vegetable intake was found to be significantly (at p <.05) associated with sensory, motor, and autonomic symptom score. Therefore, CIPN was found to have debilitating effect on QoL. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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