251. The Effect of Normally Consumed Amounts of Sucrose or High Fructose Corn Syrup on Lipid Profiles, Body Composition and Related Parameters in Overweight/Obese Subjects
- Author
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Von Nguyen, Joshua Lowndes, Sabrina Pardo, James M. Rippe, Kathleen J. Melanson, Britte E. Lowther, Stephanie Sinnett, and Zhiping Yu
- Subjects
Adult ,Male ,Sucrose ,Population ,Blood lipids ,lcsh:TX341-641 ,Fructose ,Weight Gain ,Article ,high fructose corn syrup ,Body Mass Index ,chemistry.chemical_compound ,Double-Blind Method ,Dietary Sucrose ,Medicine ,Humans ,Food science ,Obesity ,Prospective Studies ,education ,Triglycerides ,education.field_of_study ,Nutrition and Dietetics ,medicine.diagnostic_test ,High-fructose corn syrup ,business.industry ,sucrose ,Middle Aged ,Overweight ,body mass ,Diet ,Cholesterol ,chemistry ,Body Composition ,Female ,medicine.symptom ,business ,Lipid profile ,Weight gain ,lcsh:Nutrition. Foods and food supply ,Food Science - Abstract
The American Heart Association (AHA) has advocated that women and men not consume more than 100 and 150 kcal/day, respectively, from added sugars. These levels are currently exceeded by over 90% of the adult population in the United States. Few data exist on longer-term metabolic effects when sucrose and High Fructose Corn Syrup (HFCS), the principal sources of added dietary sugars, are consumed at levels typical of the general population. Sixty five overweight and obese individuals were placed on a eucaloric (weight stable) diet for 10-weeks, which incorporated sucrose- or HFCS-sweetened, low-fat milk at 10% or 20% of calories in a randomized, double-blinded study. All groups responded similarly (interaction p > 0.05). There was no change in body weight in any of the groups over the 10-week study, or in systolic or diastolic blood pressure. Likewise, there were no changes in total cholesterol, triglycerides, low-density lipoprotein (LDL), or apolipoprotein B (Apo B). We conclude that (1) when consumed as part of a eucaloric diet fructose—when given with glucose (as normally consumed) does not promote weight gain or an atherogenic lipid profile even when consumed at two to four times the level recently recommended by the AHA. (2) There were no differences between HFCS and sucrose on these parameters.
- Published
- 2014
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