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931 results on '"Vanderheyden, Marc"'

251. Percutaneous Transvenous Mitral Annuloplasty

Author

Sack, Stefan, primary, Kahlert, Philipp, additional, Bilodeau, Luc, additional, Pièrard, Luc A., additional, Lancellotti, Patrizio, additional, Legrand, Victor, additional, Bartunek, Jozef, additional, Vanderheyden, Marc, additional, Hoffmann, Rainer, additional, Schauerte, Patrick, additional, Shiota, Takahiro, additional, Marks, David S., additional, Erbel, Raimund, additional, and Ellis, Stephen G., additional

Published
2009
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256. Multicenter assessment of coronary allograft vasculopathy by intravascular ultrasound-derived analysis of plaque composition

Author

Sarno, Giovanna, primary, Lerman, Amir, additional, Bae, Jang-Ho, additional, Schukro, Christoph, additional, Glogar, Dietmar, additional, Margolis, Pauliina M, additional, Goethals, Marc, additional, Verstreken, Sofie, additional, Bartunek, Jozef, additional, Koenig, Andreas, additional, Wijns, William, additional, and Vanderheyden, Marc, additional

Published
2008
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257. Nonmyocardial Production of ST2 Protein in Human Hypertrophy and Failure Is Related to Diastolic Load

Author

Bartunek, Jozef, primary, Delrue, Leen, additional, Van Durme, Frederik, additional, Muller, Olivier, additional, Casselman, Filip, additional, De Wiest, Bart, additional, Croes, Romaric, additional, Verstreken, Sofie, additional, Goethals, Marc, additional, de Raedt, Herbert, additional, Sarma, Jaydeep, additional, Joseph, Lija, additional, Vanderheyden, Marc, additional, and Weinberg, Ellen O., additional

Published
2008
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258. Abstract 3052: Initial Human Experiences with a Non-Stented Coronary Sinus Device for the Treatment of Functional Mitral Regurgitation in Heart Failure Patients

Author

Sack, Stefan, primary, Kahlert, Philipp, additional, Bilodeau, Luc, additional, Pierard, Luc, additional, Lancellotti, Patrizio, additional, Legrand, Victor, additional, Bartunek, Jozef, additional, Vanderheyden, Marc, additional, Hoffmann, Rainer, additional, Schauerte, Patrick, additional, Shiota, Takahiro, additional, Marks, David, additional, Ellis, Stephen, additional, and Erbel, Raimund, additional

Published
2008
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261. Reply

Author

Vanderheyden, Marc, primary, Mullens, Wilfried, additional, and Bartunek, Jozef, additional

Published
2008
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263. Relation of Low Response to Clopidogrel Assessed With Point-of-Care Assay to Periprocedural Myonecrosis in Patients Undergoing Elective Coronary Stenting for Stable Angina Pectoris

Author

Cuisset, Thomas, primary, Hamilos, Michalis, additional, Sarma, Jaydeep, additional, Sarno, Giovanna, additional, Wyffels, Eric, additional, Vanderheyden, Marc, additional, Barbato, Emanuele, additional, Bartunek, Jozef, additional, De Bruyne, Bernard, additional, and Wijns, William, additional

Published
2008
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268. Early and late effects of cardiac resynchronization therapy on force–frequency relation and contractility regulating gene expression in heart failure patients

Author

Mullens, Wilfried, primary, Bartunek, Jozef, additional, Wilson Tang, W.H., additional, Delrue, Leen, additional, Herbots, Lieven, additional, Willems, Rik, additional, De Bruyne, Bernard, additional, Goethals, Marc, additional, Verstreken, Sofie, additional, and Vanderheyden, Marc, additional

Published
2008
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271. GLU-27 variant of β2-adrenergic receptor polymorphisms is an independent risk factor for coronary atherosclerotic disease

Author

Barbato, Emanuele, primary, Berger, Alexandre, additional, Delrue, Leen, additional, Van Durme, Frederik, additional, Manoharan, Ganesh, additional, Boussy, Tim, additional, Heyndrickx, Guy R., additional, De Bruyne, Bernard, additional, Ciampi, Quirino, additional, Vanderheyden, Marc, additional, Wijns, William, additional, and Bartunek, Jozef, additional

Published
2007
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272. Impact of Intracoronary Cell Therapy on Left Ventricular Function in the Setting of Acute Myocardial Infarction

Author

Lipinski, Michael J., primary, Biondi-Zoccai, Giuseppe G.L., additional, Abbate, Antonio, additional, Khianey, Reena, additional, Sheiban, Imad, additional, Bartunek, Jozef, additional, Vanderheyden, Marc, additional, Kim, Hyo-Soo, additional, Kang, Hyun-Jae, additional, Strauer, Bodo E., additional, and Vetrovec, George W., additional

Published
2007
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273. Time-Dependent Effects on Coronary Remodeling and Epicardial Conductance after Intracoronary Injection of Enriched Hematopoietic Bone Marrow Stem Cells in Patients with Previous Myocardial Infarction

Author

Vanderheyden, Marc, primary, Vercauteren, Steven, additional, Mansour, Samer, additional, Delrue, Leen, additional, Vandekerckhove, Bart, additional, Heyndrickx, Guy R., additional, Van Haute, Inge, additional, De Bruyne, Bernard, additional, Timmermans, Frank, additional, Wijns, William, additional, and Bartunek, Jozef, additional

Published
2007
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280. Role of Imaging in Cardiac Stem Cell Therapy

Author

Beeres, Saskia L.M.A., primary, Bengel, Frank M., additional, Bartunek, Jozef, additional, Atsma, Douwe E., additional, Hill, Jonathan M., additional, Vanderheyden, Marc, additional, Penicka, Martin, additional, Schalij, Martin J., additional, Wijns, William, additional, and Bax, Jeroen J., additional

Published
2007
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281. Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium

Author

Bartunek, Jozef, primary, Croissant, Jeffrey D., additional, Wijns, William, additional, Gofflot, Stephanie, additional, de Lavareille, Aurore, additional, Vanderheyden, Marc, additional, Kaluzhny, Yulia, additional, Mazouz, Naïma, additional, Willemsen, Philippe, additional, Penicka, Martin, additional, Mathieu, Myrielle, additional, Homsy, Christian, additional, De Bruyne, Bernard, additional, McEntee, Kathleen, additional, Lee, Ike W., additional, and Heyndrickx, Guy R., additional

Published
2007
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283. Impact of Alpha- and Beta-Adrenergic Receptor Blockers on Fractional Flow Reserve and Index of Microvascular Resistance.

Author

Barbato, Emanuele, Sarno, Giovanna, Berza, Catalina, Gioia, Giuseppe, Bartunek, Jozef, Vanderheyden, Marc, Serafino, Luigi, Wijns, William, Trimarco, Bruno, and Bruyne, Bernard

Abstract

We investigated the effect of β- and α-adrenergic blockers on fractional flow reserve (FFR) and index of microvascular resistance (IMR). In 43 patients (pts) with intermediate stenoses, we measured FFR and IMR before and after nonselective β-blocker propranolol (30 μg/kg, n = 20) and selective β1-blocker metoprolol (40 μg/kg, n = 23) IC; (b) In additional 21 pts after percutaneous coronary intervention (PCI), FFR and IMR were measured before and after α-blocker phentolamine (3 mg) IC. Neither propranolol nor metoprolol changed values of FFR and IMR. Phentolamine slightly decreased FFR (from 0.88 ± 0.05 to 0.87 ± 0.06, p = 0.025) but did not change IMR. FFR decreased from >0.80 to ≤0.80 in 3 pts (14 %), but in none, the value decreased to <0.75. β-blockers do not affect FFR and IMR in intermediate stenoses. After PCI, a mild decrease in FFR occurs after α-blockers, though of limited clinical impact. [ABSTRACT FROM AUTHOR]

Published
2014
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284. Evolving concepts of angiogram: fractional flow reserve discordances in 4000 coronary stenoses.

Author

Toth, Gabor, Hamilos, Michalis, Pyxaras, Stylianos, Mangiacapra, Fabio, Nelis, Olivier, De Vroey, Frederic, Di Serafino, Luigi, Muller, Olivier, Van Mieghem, Carlos, Wyffels, Eric, Heyndrickx, Guy R., Bartunek, Jozef, Vanderheyden, Marc, Barbato, Emanuele, Wijns, William, and De Bruyne, Bernard

Abstract

Aims The present analysis addresses the potential clinical and physiologic significance of discordance in severity of coronary artery disease between the angiogram and fractional flow reserve (FFR) in a large and unselected patient population. Methods and results Between September 1999 and December 2011, FFR and percent diameter stenosis (DS) as assessed by quantitative coronary angiography were obtained in 2986 patients (n = 4086 coronary stenoses), in whom at least one stenosis was of intermediate angiographic severity. Fractional flow reserve correlated slightly but significantly with DS [−0.38 (95% CI: −0.41; −0.36); P < 0.001]. The sensitivity, specificity, and diagnostic accuracy of a ≥50% DS for predicting FFR ≤ 0.80 were 61% (95% CI: 59; 63), 67% (95% CI: 65; 69), and 0.64 (95% CI: 0.56; 0.72), respectively. In different anatomical settings, sensitivity and specificity showed marked variations between 35 to 74% and 58 to 76%, respectively, resulting in a discordance in 35% of all cases for these thresholds. For an angiographic threshold of 70% DS, the diagnostic performance by the Youden's index decreased from 0.28 to 0.11 for the overall population. Conclusion The data confirm that one-third of a large patient population shows discordance between angiogram ≥50%DS and FFR ≤0.8 thresholds of stenosis severity. Left main stenoses are often underestimated by the classical 50% DS cut-off compared with FFR. This discordance offers physiologic insights for future trials. It is hypothesized that the discordance between angiography and FFR is related to technical limitations, such as imprecise luminal border detection by angiography, as well as to physiologic factors, such as variable minimal microvascular resistance. [ABSTRACT FROM PUBLISHER]

Published
2014
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285. Activation of the Ergoreceptors in Cardiac Patients With and Without Heart Failure.

Author

Pardaens, Sofie, Vanderheyden, Marc, Calders, Patrick, Willems, Anne-Marie, Bartunek, Jozef, and de Sutter, Johan

Abstract

Background The presence of ergoreflex activity and its current relationship to hyperventilation and prognosis in cardiac patients is unclear. Therefore, we evaluated ergoreflex activity in cardiac patients with and without heart failure (CHF) as well as in healthy subjects, and we examined how ergoreceptor activity was related to a mortality risk score in CHF (MAGGIC). Methods and Results Twenty-five healthy subjects and 76 patients were included, among whom were 25 with ischemic heart disease (IHD), 24 with stable CHF, and 27 with unstable CHF. Ergoreflex activity was measured with a dynamic handgrip exercise, followed by post-handgrip regional circulatory occlusion (PH-RCO). Ergoreflex activity contributed significantly to ventilation (median [interquartile range] %V) in unstable CHF (81 [73-91] %V without PH-RCO, 92 [82–107] %V with PH-RCO, and 11 [6–20] difference in %V; P < .001) and was positively correlated with the MAGGIC risk score (Spearman ρ = 0.431; P = .002). No ergoreflex activity was observed in healthy subjects (−4 [−10 to 5] difference in %V), IHD (0 [−8 to 3] Diff in %V) and stable CHF (−3 [−11 to 6] difference in %V). Conclusions Ergoreflex activity contributes to hyperventilation, but only in CHF patients with persistent symptoms, and is closely related to the MAGGIC risk score. Ergoreflex activity was not present in patients with IHD or stable CHF, suggesting other reasons for the increased ventilatory drive in those patients. [ABSTRACT FROM AUTHOR]

Published
2014
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289. Intracoronary Delivery of Hematopoietic Bone Marrow Stem Cells and Luminal Loss of the Infarct-Related Artery in Patients With Recent Myocardial Infarction

Author

Mansour, Samer, primary, Vanderheyden, Marc, additional, De Bruyne, Bernard, additional, Vandekerckhove, Bart, additional, Delrue, Leen, additional, Van Haute, Inge, additional, Heyndrickx, Guy, additional, Carlier, Stephane, additional, Rodriguez-Granillo, Gaston, additional, Wijns, William, additional, and Bartunek, Jozef, additional

Published
2006
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300. Biologic ex-vivopre differentiation of adult bone marrow-derived mesenchymal stem cells for cardiac repair in a chronic dog model of myocardial infarction

Author

Bartunek, Jozef, primary, Croissant, Jeffrey D., additional, Liu, Jeannie G., additional, Lee, Ike W., additional, De Bruyne, Bernard, additional, Wijns, William, additional, Penicka, Martin, additional, Vanderheyden, Marc, additional, Gerber, Bernard, additional, Vanoverschelde, Jean-Louis J., additional, and Heyndrickx, Guy R., additional

Published
2003
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