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251. LLM-Domain B-GATA Transcription Factors Play Multifaceted Roles in Controlling Greening in Arabidopsis.

252. Amyloid toxicity is enhanced after pharmacological or genetic invalidation of the σ1 receptor.

253. TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain.

254. Structural Insights into σ1 Receptor Interactions with Opioid Ligands by Molecular Dynamics Simulations.

255. Multifunctional thiosemicarbazones and deconstructed analogues as a strategy to study the involvement of metal chelation, Sigma-2 (σ2) receptor and P-gp protein in the cytotoxic action: In vitro and in vivo activity in pancreatic tumors.

256. Novel Sigma Receptor Ligand-Nitric Oxide Photodonors: Molecular Hybrids for Double-Targeted Antiproliferative Effect.

257. Efficacy and Safety of MIN-101: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of a New Drug in Development for the Treatment of Negative Symptoms in Schizophrenia.

258. Rho kinase inhibitors ameliorate cognitive impairment in a male mouse model of methamphetamine-induced schizophrenia.

259. Identification of drug repurposing candidates for the treatment of anxiety: A genetic approach.

260. Astatine-211-labeled aza-vesamicol derivatives as sigma receptor ligands for targeted alpha therapy.

261. DinB (DNA polymerase IV), ImuBC and RpoS contribute to the generation of ciprofloxacin-resistance mutations in Pseudomonas aeruginosa.

262. Identification of 14 glutathione S-transferase genes from Lasioderma serricorne and characterization of LsGSTe1 involved in lambda-cyhalothrin detoxification.

263. Study Data from Jagiellonian University Medical College Update Knowledge of Pruritus (Efficacy of the Multi-Target Compound E153 in Relieving Pain and Pruritus of Different Origins).

264. Highly specific s2R/TMEM97 ligand alleviates neuropathic pain and inhibits the integrated stress response (Updated October 17, 2023).

265. Researcher from Texas Tech University Health Sciences Center Discusses Findings in Opioid Receptors (Sigma Receptors: Novel Regulators of Iron/Heme Homeostasis and Ferroptosis).

266. Researchers' Work from University of Texas Austin Focuses on Obesity, Fitness and Wellness (Structure-affinity Relationships of Stereoisomers of Norbenzomorphan-derived Ci2r/tmem97 Modulators).

267. Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands.

268. Do spiroindolines have the potential to replace vesamicol as lead compound for the development of radioligands targeting the vesicular acetylcholine transporter?

269. Sigma Receptor (σR) Ligands with Antiproliferative and Anticancer Activity.

270. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis.

271. Identification of the gene that codes for the σ2 receptor.

272. σ-1 receptor stimulation protects against pressure-induced damage through InsR-MAPK signaling in human trabecular meshwork cells.

273. Nanoencapsulation strategies for the delivery of novel bifunctional antioxidant/σ1 selective ligands.

274. Sigma-2 ligands and PARP inhibitors synergistically trigger cell death in breast cancer cells.

275. Isolation and characterization of alternatively spliced variants of the mouse sigma1 receptor gene, Sigmar1.

276. (+)-Pentazocine attenuates SH-SY5Y cell death, oxidative stress and microglial migration induced by conditioned medium from activated microglia.

277. Small molecule modulator of sigma 2 receptor is neuroprotective and reduces cognitive deficits and neuroinflammation in experimental models of Alzheimer's disease.

278. Catalytic sp3-sp3 Functionalisation of Sulfonamides: Late-Stage Modification of Drug-Like Molecules.

279. S2RSLDB: a comprehensive manually curated, internet-accessible database of the sigma-2 receptor selective ligands.

280. Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines.

281. Autophagy-mediated circHIPK2 promotes lipopolysaccharide-induced astrocytic inflammation via SIGMAR1.

282. Steam explosion pretreatment coupling high-temperature short-time sterilization facilitating cellulose degradation and sporulation-regulatory gene expression in high-solid fermentation.

283. Ketamine and serotonergic psychedelics: An update on the mechanisms and biosignatures underlying rapid-acting antidepressant treatment.

284. CharTM: The dynamic stability characterization for memory based on tail distribution modeling.

285. Analytical evaluation and Sigma metrics of 6 next generation chemistry assays on the Abbott Architect system.

286. Answering Big Questions in Pain Medicine.

287. Sigma-2 receptor ligand anchored telmisartan loaded nanostructured lipid particles augmented drug delivery, cytotoxicity, apoptosis and cellular uptake in prostate cancer cells.

289. Contribution of Lysosome and Sigma Receptors to Neuroprotective Effects of Memantine Against Beta-Amyloid in the SH-SY5Y Cells

291. Researcher from Beijing Normal University Describes Findings in Alzheimer Disease (The Sigma Receptors in Alzheimer's Disease: New Potential Targets for Diagnosis and Therapy).

292. Reports Outline Cytokines Study Findings from City University of New York (CUNY) (Interleukin 24: Signal Transduction Pathways).

293. Data from University of Toledo Broaden Understanding of Personalized Medicine (An Emerging Role for Sigma Receptor 1 in Personalized Treatment of Breast Cancer).

294. New Findings from University of Texas Health Science Center San Antonio Describe Advances in Opioid Receptors (3,4-methylenedioxypyrovalerone High-responder Phenotype As a Tool To Evaluate Candidate Medications for Stimulant Use Disorder).

295. "Amines For Use As Sigma Receptor Modulators" in Patent Application Approval Process (USPTO 20230159505).

296. A Role for Sigma Receptors in Stimulant Self Administration and Addiction

297. Lonp1 and Sig-1R contribute to the counteraction of ursolic acid against ochratoxin A-induced mitochondrial apoptosis.

298. A σE-mediated temperature gauge orchestrates type VI secretion system, biofilm formation and cell invasion in pathogen Pseudomonas plecoglossicida.

299. Neuroprotective effect of histamine H3 receptor blockade on methamphetamine-induced cognitive impairment in mice.

300. Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands.

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