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253 results on '"Sandro Pontremoli"'

251. Absence of β-Globin Synthesis and Excess of α-Globin Synthesis in Homozygous β-Thalassaemic Subjects from the Ferrara Region

Author

S. Volpato, A. Bargellesi, D. Gaburro, V. Vigi, Francesco Conconi, and Sandro Pontremoli

Subjects
Electrophoresis, Heterozygote, Blood transfusion, medicine.medical_treatment, Biology, Tritium, α globin, Hemoglobins, hemic and lymphatic diseases, medicine, Humans, Blood Transfusion, Globin, Amino Acids, Child, Normal range, Messenger RNA, Multidisciplinary, Homozygote, Infant, Starch, Blood Proteins, Chromatography, Ion Exchange, Molecular biology, Globins, Beta-thalassaemia, medicine.anatomical_structure, Italy, Child, Preschool, Immunology, Thalassemia, Bone marrow, Gels, Megakaryocytes
Abstract

β-THALASSAEMIA is a genetically determined anaemia of man, characterized by a decrease in production1–6 or the absence7 of β-globin, and by an excess of α-globin synthesis4,6–8, which results in the α/(β + γ + δ) globin synthesis ratio largely exceeding the normal value of 1.0.

Published
1968
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252. MEDITERRANEAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE (G6PD) DEFICIENCY: A GENETIC DISORDER WITH COMPLE TE ABSENCE OF ERYTHROCYTE G6PD ACTIVITY

Author

Sandro Pontremoli, L Lenzerini, Alessandro Morelli, Edon Melloni, Bianca Sparatore, Mauro Michetti, Franca Salamino, Umberto Benatti, and A. De Flora

Subjects
Mediterranean climate, chemistry.chemical_compound, Biochemistry, Chemistry, G6PD activity, Genetic disorder, medicine, Glucose-6-phosphate dehydrogenase, medicine.disease
Published
1981
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