Search

Your search keyword '"Rushing, Elisabeth J"' showing total 757 results
Start Over Author "Rushing, Elisabeth J"
757 results on '"Rushing, Elisabeth J"'

253. Proteomic characterization of primary diffuse large B-cell lymphomas in the central nervous system

Author

Li, Jie, primary, Okamoto, Hiroaki, additional, Yin, Chunyue, additional, Jagannathan, Jay, additional, Takizawa, Jun, additional, Aoki, Sadao, additional, Gläsker, Sven, additional, Rushing, Elisabeth J., additional, Vortmeyer, Alexander O., additional, Oldfield, Edward H., additional, Yamanaka, Ryuya, additional, and Zhuang, Zhengping, additional

Published
2008
Full Text
View/download PDF

266. Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease.

Author

Varsani, Hemlata, Charman, Susan C., Li, Charles K., Marie, Suely K. N., Amato, Anthony A., Banwell, Brenda, Bove, Kevin E., Corse, Andrea M., Emslie-Smith, Alison M., Jacques, Thomas S., Lundberg, Ingrid E., Minetti, Carlo, Nennesmo, Inger, Rushing, Elisabeth J., Sallum, Adriana M. E., Sewry, Caroline, Pilkington, Clarissa A., Holton, Janice L., and Wedderburn, Lucy R.

Abstract

Objectives To study muscle biopsy tissue from patients with juvenile dermatomyositis ( JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to quadriceps femoris. Additionally, to evaluate whether elements of the tool correlate with clinical measures of disease severity. Methods 55 patients with JDM with muscle biopsy tissue and clinical data available were included. Biopsy samples (33 quadriceps, 22 biceps) were prepared and stained using standardised protocols. A Latin square design was used by the International Juvenile Dermatomyositis Biopsy Consensus Group to score cases using our previously published score tool. Reliability was assessed by intraclass correlation coefficient (ICC) and scorer agreement (α) by assessing variation in scorers' ratings. Scores from the most reliable tool items correlated with clinical measures of disease activity at the time of biopsy. Results Inter- and intraobserver agreement was good or high for many tool items, including overall assessment of severity using a Visual Analogue Scale. The tool functioned equally well on biceps and quadriceps samples. A modified tool using the most reliable score items showed good correlation with measures of disease activity. Conclusions The JDM biopsy score tool has high interand intraobserver agreement and can be used on both biceps and quadriceps muscle tissue. Importantly, the modified tool correlates well with clinical measures of disease activity. We propose that standardised assessment of muscle biopsy tissue should be considered in diagnostic investigation and clinical trials in JDM. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

267. Rare giant cell ependymoma in an octogenarian

Author

Cooper, Patrick B., primary, Katus, Matthew, additional, Moores, Leon, additional, Geyer, Dennis, additional, Smirniotopoulos, James G., additional, Sandberg, Glenn D., additional, and Rushing, Elisabeth J., additional

Published
2006
Full Text
View/download PDF

270. Proteomic Analysis of Inclusion Body Myositis

Author

Li, Jie, primary, Yin, Chunyue, additional, Okamoto, Hiroaki, additional, Jaffe, Howard, additional, Oldfield, Edward H., additional, Zhuang, Zhengping, additional, Vortmeyer, Alexander O., additional, and Rushing, Elisabeth J., additional

Published
2006
Full Text
View/download PDF

282. West Nile Poliomyelitis

Author

Holman, Robert P., primary, Monserrate, Nicole M., additional, Czander, Eric W., additional, and Rushing, Elisabeth J., additional

Published
2004
Full Text
View/download PDF

289. Spinal cord malignant astrocytomas

Author

Santi, Mariarita, primary, Mena, Hernando, additional, Wong, Kondi, additional, Koeller, Kelly, additional, Olsen, Cara, additional, and Rushing, Elisabeth J., additional

Published
2003
Full Text
View/download PDF

293. Gustatory Function of Patients With and Without Cholesteatoma Undergoing Middle Ear Surgery.

Author

Neumann, Aline Sophie, Soyka, Michael B., Rushing, Elisabeth J., and Röösli, Christof

Subjects
*MIDDLE ear surgery, *CHRONIC diseases, *CHOLESTEATOMA, *TREATMENT effectiveness, *COMPARATIVE studies, *DESCRIPTIVE statistics, *QUESTIONNAIRES, *TASTE, *OTITIS media, *SKULL tumors, *LONGITUDINAL method, *EVALUATION, FACIAL nerve surgery
Abstract

Objective: To compare measured and perceived taste function before and after surgery of patients with chronic otitis media with cholesteatoma (OMCC) to patients without cholesteatoma (patients with chronic suppurative otitis media [CSOM] and patients with lateral skull base lesions [LSB]). Methods: This prospective cohort study included 29 patients undergoing surgery for unilateral OMCC. The chorda tympani nerve (CTN) was resected in 8 of these patients. Fourteen patients undergoing surgery for unilateral CSOM and 5 patients undergoing surgery for unilateral LSB (with CTN resection) served as the comparison group. Taste function was measured using taste strips on both sides of the tongue before surgery, 2 weeks postoperatively and 3 months postoperatively. The affected side of the tongue was compared to the unaffected side. A questionnaire on taste perception was completed at each visit. Results: Preoperatively, cholesteatoma patients showed higher taste strip scores than non-cholesteatoma patients, indicating a larger difference between the healthy and affected sides of the tongue. Despite this difference in measured taste function few cholesteatoma patients reported taste alteration before surgery (3/29 [10.3%]). Postoperatively, patients with CTN resection (OMCC patients with CTN resection and LSB patients) showed a decreased measured taste function. Subjectively, only approximately 20% of these patients reported taste alteration 3 months postoperatively. Conclusions: Before surgery, cholesteatoma patients displayed an impaired measured taste function compared to patients without cholesteatoma (CSOM, LSB). Subjectively this was often unnoticed. After surgery, despite removal of the CTN and consequent reduction of measured taste function, few patients reported taste alteration and subjective taste perception was seen to be improving. In regards to middle ear surgery, perceived taste function does not seem to reflect measured gustatory function. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results