3,299 results on '"Remington PL"'
Search Results
252. Geographic access to pediatric neurosurgeons in the USA: an analysis of sociodemographic factors.
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Farivar, Daniel, Peterman, Nicholas J., Narendran, Nakul, Illingworth, Kenneth D., Nuckols, Teryl K., Bonda, David, and Skaggs, David L.
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NEUROSURGEONS ,SOCIODEMOGRAPHIC factors ,FACTOR analysis ,AMERICAN Community Survey - Abstract
Purpose: Geographic access to physicians has been shown to be unevenly distributed in the USA, with those in closer proximity having superior outcomes. The purpose of this study was to describe how geographic access to pediatric neurosurgeons varies across socioeconomic and demographic factors. Methods: Actively practicing neurosurgeons were identified by matching several registries and membership logs. This data was used to find their primary practice locations and the distance the average person in a county must travel to visit a surgeon. Counties were categorized into "surgeon deserts" and "surgeon clusters," which were counties where providers were significantly further or closer to its residents, respectively, compared to the national average. These groups were also compared for differences in population characteristics using data obtained from the 2020 American Community Survey. Results: A total of 439 pediatric neurosurgeons were identified. The average person in a surgeon desert and cluster was found to be 189.2 ± 78.1 miles and 39.7 ± 19.6 miles away from the nearest pediatric neurosurgeon, respectively. Multivariate analyses showed that higher Rural–Urban Continuum (RUC) codes (p < 0.001), and higher percentages of American Indian (p < 0.001) and Hispanic (p < 0.001) residents were independently associated with counties where the average person traveled significantly further to surgeons. Conclusion: Patients residing in counties with greater RUC codes and higher percentages of American Indian and Hispanic residents on average need to travel significantly greater distances to access pediatric neurosurgeons. [ABSTRACT FROM AUTHOR]
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- 2024
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253. ISHRANA I GLOBALNA SIGURNOST HRANE ZA OČUVANJE ZDRAVLJA.
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Vulović, Jelena, knežević, Snežana, Petrović, Olivera, radulović, Miroslav, and Dugalić, Elka
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Copyright of Medical Gazette / Medicinski Glasnik is the property of Specijalna bolnica za bolesti stitaste zlezde i bolesti metabolizma Zlatibor and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
254. Perceived Impact and Feasibility of Health Equity Policy Actions among Obesity Practitioners, Researchers, and Policymakers.
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Morshed, Alexandra B., Madas, Valerie, Kang, Sarah J., Thomas, Fanice, Tabak, Rachel G., Thomas, Ian, Politi, Mary C., Eyler, Amy A., Haire-Joshu, Debra, Dodson, Elizabeth A., Tsai, Edward, Parks, Renee G., and Brownson, Ross C.
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Objective: There is a broad array of health equity policy actions that may be important for addressing social determinants of obesity. The objective of this study was to identify local policy actions most salient for addressing health equity among practitioners, policymakers, and researchers active in obesity. Methods: We surveyed 195 participants in August-November 2020, including US public health practitioners, local policymakers, and researchers active in obesity policy or health equity. We asked them to select the most important health equity policy actions and rate them for potential impact and feasibility. Results: Living wage and access to early education scored highly across 3 dimensions of importance, potential impact, and feasibility among 3 of the 4 groups -- local public service employees and policymakers, academics, and others. Local public service employees and policymakers also rated expanded childcare and job/skills training programs highly across all 3 dimensions. Respondents rated policy actions higher for potential impact than feasibility. Conclusions: We present novel, timely findings for prioritizing health equity policy actions for addressing obesity at the local level. Several policy actions not typically considered in obesity research were identified as salient by groups relevant to local obesity policymaking. [ABSTRACT FROM AUTHOR]
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- 2024
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255. Discrimination in the medical setting among LGBTQ+ adults and associations with cancer screening.
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Stenzel AE, Rider GN, Wicker OS, Dona AC, Teoh D, Rosser BRS, and Vogel RI
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Purpose: Lesbian, gay, bisexual, transgender, queer, and other sexual and gender diverse (LGBTQ+) individuals experience disparities in cancer screening. We examined whether experience of LGBTQ+ -related discrimination in medical settings was associated with cancer screening disparities., Methods: Participants were recruited via social media for a cross-sectional survey study. Those who self-reported as LGBTQ+ , being 40+ years of age, and residing in the US were eligible. Participants reported their clinical and demographic characteristics, cancer screening history, and experiences of discrimination in a medical setting. We examined the odds (OR) of ever undergoing cancer screening by experienced discrimination, stratified by sex assigned at birth., Results: Participants (n = 310) were on average 54.4 ± 9.0 years old and primarily White (92.9%). Most identified as lesbian (38.1%) or gay (40.0%) while 17.1% were transgender or gender diverse. Nearly half (45.5%) reported experiencing LGBTQ+ -related discrimination in the medical setting. Participants assigned female at birth with discriminatory experiences had significantly lower odds of ever undergoing colonoscopy/sigmoidoscopy compared to those without discriminatory experiences (OR: 0.37; 95% Confidence Interval (CI) 0.15-0.90). No significant differences in colonoscopy/sigmoidoscopy uptake were observed in those assigned male at birth by discriminatory experiences (OR: 2.02; 95% CI 0.59-6.91). Pap tests, mammogram, and stool colorectal cancer screening did not differ by discriminatory experience., Conclusion: Discrimination in medical settings was commonly reported by LGBTQ+ individuals in this study. When treating LGBTQ+ patients, clinicians should ask about prior experiences and continue to promote cancer screening. Future studies should examine discrimination as a key driver of LGBTQ+ disparities in cancer screening., (© 2024. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
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- 2024
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256. The role of socioeconomic status in resolution of type 2 diabetes mellitus following longitudinal sleeve gastrectomy.
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Doan TD, Suh L, Wu M, Cherng N, and Perugini R
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Introduction: The role socioeconomic status (SES) on outcomes following bariatric surgery has been heavily investigated in previous studies. The goal of this study is to determine the association between Area Deprivation Index (ADI), a multidimensional indicator of socioeconomic conditions, and remission of type 2 diabetes mellitus following longitudinal sleeve gastrectomy (SG)., Methods: This is a retrospective analysis of 312 patients undergoing LSG at a single-center in a metropolitan hospital setting over two years. Socioeconomic disadvantage was assessed by ADI, a model that incorporates education, income, employment and housing stock to rank neighborhoods both on the state and the national level. Type 2 diabetes mellitus (T2DM) was defined as utilization of diabetes medication or HgA1C of greater than 6.5% within a 3 months period, and was assessed at three time points: pre-op, 6-month follow-up and 1-year follow-up., Results: In this cohort of individuals presenting for LSG, 72 (23.1%) had T2DM. The mean ADI of patients with T2DM (41.1 ± 17.1) was not statistically different from the group without T2DM (45.0 ± 16.4; p = 0.08631). By one year follow-up, 39 (60.0%) of individuals with T2DM had achieved remission. The ADI for individuals that achieved T2DM resolution was not different from the ADI of the group that did not (38.1 ± 15.4 vs 45.3 ± 17.7; p = 0.0958). In individuals with T2DM at baseline, 47 (65%) had A1C pre-op and A1C at 1 year follow-up; there was a significant reduction in Hgb-A1c (-0.71; -12.3%; p < 0.01). There was no correlation between change in A1C at 1 year and ADI national rank (p = 0.26)., Discussion: We did not find a significant association between ADI and resolution of T2DM following sleeve gastrectomy. Resolution of T2DM following SG can be achieved by individuals regardless of SES. This supports the continued use of SG for socioeconomically deprived populations. In addition, we did not find an association between resolution of T2DM and weight loss, the most commonly used outcome metric following bariatric surgery., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2024
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257. The Impact of Tocilizumab Coverage on Health Equity for Inpatients with COVID-19 in the USA: A Distributional Cost-Effectiveness Analysis.
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Kowal S and Rosettie KL
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Objectives: We conducted a distributional cost-effectiveness analysis to evaluate how coverage of tocilizumab for inpatients with COVID-19 from 2021 to present impacted health equity in the USA., Methods: A published, payer-perspective, distributional cost-effectiveness analysis for inpatient COVID-19 treatments was adapted to include information on baseline health disparities across 25 equity-relevant subgroups based on race and ethnicity (5 census-based groups), and county-level social vulnerability (5 geographic quintiles). The underlying cost-effectiveness analysis was updated to reflect patient characteristics at admission, standard of care outcomes, tocilizumab efficacy, and contemporary unit costs. The distributional cost-effectiveness analysis inputs for COVID-19 hospitalization and subgroup risk adjustments based on social vulnerability were derived from published estimates. Opportunity costs were estimated by converting total tocilizumab spend into quality-adjusted life-years (QALYs), distributed equally across subgroups., Results: Tocilizumab treatment was cost effective across all subgroups. Treatment resulted in larger relative QALY gains in more socially vulnerable subgroups than less socially vulnerable subgroups, given higher hospitalization rates and inpatient mortality. Using an opportunity cost threshold of US$150,000/QALY and an Atkinson index of 11, tocilizumab was estimated to have improved social welfare by increasing population health (53,252 QALYs gained) and reducing existing overall US health inequalities by 0.003% since 2021., Conclusions: Use of tocilizumab for COVID-19 since 2021 increased population health while improving health equity, as more patients with lower baseline health were eligible for treatment and received larger relative health gains. Future equitable access to tocilizumab for inpatients with COVID-19 is expected to lead to continued increases in population health and reductions in disparities., (© 2024. The Author(s).)
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- 2024
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258. Social determinants of health and diabetes: using a nationally representative sample to determine which social determinant of health model best predicts diabetes risk.
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Cooper, Zach W., Mowbray, Orion, and Johnson, Leslie
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- 2024
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259. Prioritizing determinants of cognitive function in healthy middle-aged and older adults: insights from a machine learning regression approach in the Canadian longitudinal study on aging.
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Singh, Sarah, Zhong, Shiran, Rogers, Kem, Hachinski, Vladimir, and Frisbee, Stephanie
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- 2024
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260. Recreational athletes during downhill-mountain biking (DMB) show high incidence of upper extremity fractures in combination with soft-tissue injuries.
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Breulmann, Franziska Lioba, Krenn, Claudia, Fraißler, Lukas, Kindermann, Harald, Gattringer, Michael, Gruber, Michael Stephan, Siebenlist, Sebastian, Mattiassich, Georg Philipp, and Bischofreiter, Martin
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CYCLING ,SHOULDER injuries ,FORELIMB ,OLDER patients ,WOUNDS & injuries ,SHOULDER - Abstract
Downhill-mountain biking (DMB) is a high-risk sport and often leads to several injuries, especially in non-professional athletes. We retrospectively analyzed the most common injuries and profiled the injury mechanism. Until now, there is no such analysis of injuries by non-professional mountain bike athletes. We collected patient data from patients who suffered from an injury during DMB. The inclusion criteria were (1) injury during the summer season of 2020 and 2021, (2) injury during off-road and downhill mountain bike sports activity, and (3) treatment at the Department of Traumatology of the Klinik Diakonissen Schladming. Patient data was analyzed regarding the type of injury, location of the injury, patient age and gender of the patients. Most patients with injury are at the age of 26–35. Second most are between 36 and 71 years old. The type of injury differs between age and gender. Mostly upper-extremity injuries occur with a high probability of shoulder injuries. In the elderly patients, we found additional injuries of the thorax and chest. To conclude, most common types of injuries are soft-tissue injuries, often in combination with fractures. The risk for injuries is higher for recreational athletes with different injury characteristics than professional athletes. [ABSTRACT FROM AUTHOR]
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- 2024
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261. Helping Others Facilitates Well-Being for Indigenous Peoples Living With HIV/AIDS in Canada.
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Skov B, Grouzet FME, Briatico C, Jackson R, Masching R, Parsons M, Peltier D, and Turner D
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- Adult, Female, Humans, Male, Middle Aged, Canada epidemiology, Helping Behavior, Interviews as Topic, Qualitative Research, Social Support, Spirituality, Surveys and Questionnaires, HIV Infections psychology, HIV Infections ethnology, Indigenous Canadians psychology
- Abstract
Research has found that helping others facilitates well-being for Indigenous peoples living with HIV and AIDS, but limited research exists that investigates the mechanism(s) underlying this relationship. Indigenous perspectives posit that helping others facilitates well-being through the development of an individual's spiritual, physical, emotional, and mental aspects (four aspects). Similarly, self-determination theory posits that helping others facilitates well-being by satisfying basic psychological needs. In the present study, we examined if helping others facilitates well-being through the fulfillment of the spiritual, physical, emotional, and mental aspects among Indigenous peoples living with HIV and AIDS. We used a convergent parallel mixed methods design, coupled with a community-engaged approach grounded in the United Nations Greater Involvement of People Living with HIV and AIDS principles and Indigenous and decolonizing research methodologies. Survey (n = 117) and interview data (n = 9) collected by an Indigenous-led HIV/AIDS organization in Canada were employed to examine the relationship between helping, the four aspects, and well-being. Participants were primarily First Nations leaders and mentors who live with HIV/AIDS, with some Métis and Inuit. A parallel multiple mediation model and reflexive thematic analysis were used to analyze the relationship between helping, the four aspects, and well-being. Mixed-methods findings support the idea that helping others promotes well-being by fulfilling the emotional and mental aspects. Qualitative findings demonstrated this relationship for all four aspects. This research may facilitate the development of programs to support Indigenous peoples living with HIV/AIDS well-being and contribute to the literature on integrating Indigenous perspectives and methodologies within psychological research., (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
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- 2024
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262. Occupational inequalities in mortality from cardiovascular disease, 2020-2021.
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Hawkins D, Thomas K, and Landsbergis P
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- Humans, Male, Female, Middle Aged, Adult, United States epidemiology, Risk Factors, Health Status Disparities, Aged, Occupational Diseases mortality, Young Adult, Socioeconomic Factors, Death Certificates, Cardiovascular Diseases mortality, Occupations statistics & numerical data
- Abstract
Background: In recent years previous declines in cardiovascular disease (CVD) have stalled. There are occupational risk factors for CVD mortality. This study seeks to examine inequalities in CVD mortality for working-age adults in the United States by occupation., Methods: Death certificate data for CVD deaths were obtained from the National Center for Health Statistics. Occupation data from these death certificates were coded to major occupation groups. Using information about the number of workers employed in these occupations obtained from the American Community Survey, we calculated mortality rates and rate ratios (RRs), adjusted for covariates associated with CVD mortality., Results: After adjusting for age, sex, race/ethnicity, and educational attainment, workers in 11 occupations had significantly elevated RRs: food preparation and serving; construction and extraction; arts, design, entertainment, sports, and media; life, physical, and social science; farming, fishing, and forestry; legal; protective services; building and grounds cleaning and maintenance; healthcare practitioners and technical; personal care and service; and community and social services., Conclusions: Occupation appears to be a significant predictor of CVD mortality. Further research is needed to assess how occupational risk factors contribute to changing trends for CVD mortality. Interventions are needed to address workplace risk factors for CVD., (© 2024 Wiley Periodicals LLC.)
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- 2024
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263. The challenges of epidemiologic translation: communicating with physicians, policymakers, and the public.
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Levin, Jeff
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- 2024
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264. Breast cancer survivorship needs: a qualitative study.
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Khajoei, Rahimeh, Azadeh, Payam, ZohariAnboohi, Sima, Ilkhani, Mahnaz, and Nabavi, Fatemah Heshmati
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MEDICAL care ,BREAST cancer ,FAMILY support ,PSYCHOTHERAPY ,CANCER relapse ,ABUSE of older people ,ATHLETIC trainers - Abstract
Background: Breast cancer rates and the number of breast cancer survivors have been increasing among women in Iran. Effective responses from healthcare depend on appropriately identifying survivors' needs. This study investigated the experience and needs of breast cancer survivors in different dimensions. Methods: In this qualitative content analysis, semi-structured in-depth interviews were conducted from April 2023 to July 2023. Data saturation was achieved after interviewing 16 breast cancer survivors (BCSs) and four oncologists using purposive sampling. Survivors were asked to narrate their experiences about their needs during the survivorship. Data were analyzed with an inductive approach in order to extract the themes. Results: Twenty interviews were conducted. The analysis focused on four central themes: (1) financial toxicity (healthcare costs, unplanned retirement, and insurance coverage of services); (2) family support (emotional support, Physical support); (3) informational needs (management of side effects, management of uncertainty, and balanced diet); and (4) psychological and physical issues (pain, fatigue, hot flashes, and fear of cancer recurrence). Conclusions: This study provides valuable information for designing survivorship care plans. Identifying the survivorship needs of breast cancer survivors is the first and most important step, leading to optimal healthcare delivery and improving quality of life. It is recommended to check the financial capability of patients and take necessary measures for patients with financial problems. Additionally, support sources should be assessed and appropriate. Psychological interventions should be considered for patients without a support source. Consultation groups can be used to meet the information needs of patients. For patients with physical problems, self-care recommendations may also be useful in addition to doctors' orders. [ABSTRACT FROM AUTHOR]
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- 2024
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265. Breast cancer outcomes based on method of detection in community-based breast cancer registry.
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Bennett, Debbie Lee, Winter, Andrea Marie, Billadello, Laura, Lowdermilk, Mary Catherine, Doherty, Christina Michelle, Kazmi, Sakina, Laster, Sydney, Al-Hammadi, Noor, Hardy, Anna, Kopans, Daniel B., and Moy, Linda
- Abstract
Purpose: The impact of opportunistic screening mammography in the United States is difficult to quantify, partially due to lack of inclusion regarding method of detection (MOD) in national registries. This study sought to determine the feasibility of MOD collection in a multicenter community registry and to compare outcomes and characteristics of breast cancer based on MOD. Methods: We conducted a retrospective study of breast cancer patients from a multicenter tumor registry in Missouri from January 2004 - December 2018. Registry data were extracted by certified tumor registrars and included MOD, clinicopathologic information, and treatment. MOD was assigned as screen-detected or clinically detected. Data were analyzed at the patient level. Chi-squared tests were used for categorical variable comparison and Mann-Whitney-U test was used for numerical variable comparison. Results: 5351 women (median age, 63 years; interquartile range, 53–73 years) were included. Screen-detected cancers were smaller than clinically detected cancers (median size 12 mm vs. 25 mm; P <.001) and more likely node-negative (81% vs. 54%; P <.001), lower grade (P <.001), and lower stage (P <.001). Screen-detected cancers were more likely treated with lumpectomy vs. mastectomy (73% vs. 41%; P <.001) and less likely to require chemotherapy (24% vs. 52%; P <.001). Overall survival for patients with invasive breast cancer was higher for screen-detected cancers (89% vs. 74%, P <.0001). Conclusion: MOD can be routinely collected and linked to breast cancer outcomes through tumor registries, with demonstration of significant differences in outcome and characteristics of breast cancers based on MOD. Routine inclusion of MOD in US tumor registries would help quantify the impact of opportunistic screening mammography in the US. [ABSTRACT FROM AUTHOR]
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- 2024
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266. Effective public health messaging for university students: lessons learned to increase adherence to safety guidelines during a pandemic.
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Milich, Krista M., Fisher, Natalie, and Sobral, Gisela
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RISK perception ,PUBLIC health ,COVID-19 pandemic ,DISEASE outbreaks ,PANDEMICS ,INFORMATION resources - Abstract
Variation in compliance with recommended safety behaviors early in the COVID-19 pandemic was especially concerning in places where people aggregated after traveling from a range of geographical areas, such as many universities. Understanding variation in these behaviors is important for continuing to address the COVID-19 pandemic and planning for future disease outbreaks. We examined the relationship between safety behaviors, risk perception, COVID-19-related knowledge, and information sources among university students during the Fall 2020 semester. A person's preferred information sources were associated with differences in knowledge, risk perception, and protective behaviors. Furthermore, people with higher COVID knowledge practiced more protective behaviors. Providing reliable information can reduce harm during future global health crises, particularly at universities where interventions on campus can also protect the larger community, as spillover from universities has impacted the most vulnerable members of the surrounding communities. Our study adds to public health literature on factors influencing personal behaviors. [ABSTRACT FROM AUTHOR]
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- 2024
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267. 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes—2024.
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American Diabetes Association Professional Practice Committee, ElSayed, Nuha A., Aleppo, Grazia, Bannuru, Raveendhara R., Beverly, Elizabeth A., Bruemmer, Dennis, Collins, Billy S., Darville, Audrey, Ekhlaspour, Laya, Hassanein, Mohamed, Hilliard, Marisa E., Johnson, Eric L., Khunti, Kamlesh, Lingvay, Ildiko, Matfin, Glenn, McCoy, Rozalina G., Perry, Mary Lou, Pilla, Scott J., Polsky, Sarit, and Prahalad, Priya
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HEALTH behavior ,WELL-being ,DIABETES ,PROFESSIONAL practice - Abstract
The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC. [ABSTRACT FROM AUTHOR]
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- 2024
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268. 3. Prevention or Delay of Diabetes and Associated Comorbidities: Standards of Care in Diabetes—2024.
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American Diabetes Association Professional Practice Committee, ElSayed, Nuha A., Aleppo, Grazia, Bannuru, Raveendhara R., Bruemmer, Dennis, Collins, Billy S., Ekhlaspour, Laya, Gaglia, Jason L., Hilliard, Marisa E., Johnson, Eric L., Khunti, Kamlesh, Lingvay, Ildiko, Matfin, Glenn, McCoy, Rozalina G., Perry, Mary Lou, Pilla, Scott J., Polsky, Sarit, Prahalad, Priya, Pratley, Richard E., and Segal, Alissa R.
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DIABETES ,PROFESSIONAL practice - Abstract
The American Diabetes Association (ADA) "Standards of Care in Diabetes" includes the ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Committee, an interprofessional expert committee, are responsible for updating the Standards of Care annually, or more frequently as warranted. For a detailed description of ADA standards, statements, and reports, as well as the evidence-grading system for ADA's clinical practice recommendations and a full list of Professional Practice Committee members, please refer to Introduction and Methodology. Readers who wish to comment on the Standards of Care are invited to do so at professional.diabetes.org/SOC. [ABSTRACT FROM AUTHOR]
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- 2024
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269. Effect of neighborhood and individual-level socioeconomic factors on breast cancer screening adherence in a multi-ethnic study.
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Kasper, Gillian, Momen, Mahsa, Sorice, Kristen A., Mayhand, Kiara N., Handorf, Elizabeth A., Gonzalez, Evelyn T., Devlin, Amie, Brownstein, Kirsten, Esnaola, Nestor, Fisher, Susan G., and Lynch, Shannon M.
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EARLY detection of cancer ,BREAST cancer ,SOCIOECONOMIC factors ,NEIGHBORHOODS ,MEDICAL screening - Abstract
Background: Although mammography can significantly reduce breast cancer mortality, many women do not receive their annual breast cancer screening. Differences in screening adherence exist by race/ethnicity, socioeconomic status (SES), and insurance status. However, more detailed investigations into the impact of neighborhood disadvantage and access to resources on screening adherence are lacking. Methods: We comprehensively examined the effect of individual social, economic, and demographic factors (n = 34 variables), as well as neighborhood level SES (nSES) indicators (n = 10 variables) on breast cancer screening adherence across a multi-ethnic population (n = 472). In this cross-sectional study, participants were surveyed from 2017 to 2018. The data was analyzed using univariate regression and LASSO for variable reduction. Significant predictors were carried forward into final multivariable mixed-effect logistic regression models where odds ratios (OR), 95% confidence intervals and p-values were reported. Results: Nineteen percent of participants were non-adherent to breast screening guidelines. Race/ethnicity was not associated with adherence; however, increasing age (OR = 0.97, 95%CI = 0.95–0.99, p = 0.01), renting a home (OR = 0.53, 95%CI = 0.30–0.94, p = 0.04), food insecurity (OR 0.46, 95%CI = 0.22–0.94, p = 0.01), and overcrowding (OR = 0.58, 95% CI = 0.32–0.94, p = 0.01) were significantly associated with lower breast cancer screening adherence. Conclusion: Socioeconomic indicators at the individual and neighborhood levels impact low breast cancer screening adherence and may help to inform future screening interventions. [ABSTRACT FROM AUTHOR]
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- 2024
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270. Amputation Rates and Associated Social Determinants of Health in the Most Populous US Counties.
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Kassavin, Daniel, Mota, Lucas, Ostertag-Hill, Claire A., Kassavin, Monica, Himmelstein, David U., Woolhandler, Steffie, Wang, Sophie X., Liang, Patric, Schermerhorn, Marc L., Vithiananthan, Sivamainthan, and Kwoun, Moon
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- 2024
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271. Gene-Environment Interaction of Interleukin 10 Gene Polymorphism, rs1800896, with Lifestyle on Cardiovascular Risk in Type 2 Diabetes.
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Udenze, Ifeoma Christiana, Taiwo, Idowu Adewunmi, Amadi, Casmir E., and Adeyemo, Wasiu Lanre
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LIFESTYLES ,RISK assessment ,RESEARCH funding ,POLYMERASE chain reaction ,LOGISTIC regression analysis ,PROBABILITY theory ,SMOKING ,SEDENTARY lifestyles ,STATISTICAL sampling ,MULTIPLE regression analysis ,CARDIOVASCULAR diseases risk factors ,DESCRIPTIVE statistics ,CHI-squared test ,GENETIC polymorphisms ,ODDS ratio ,TYPE 2 diabetes ,CASE-control method ,ONE-way analysis of variance ,STATISTICS ,CONFIDENCE intervals ,COMPARATIVE studies ,DATA analysis software ,PHENOTYPES ,INTERLEUKINS ,GENOTYPES - Abstract
Background: Gene–environment interactions play a major role in the phenotypic expression of complex disease traits such as those for cardiovascular diseases. Aims: This study aimed to determine the gene–environment interactions that underpin the relationship between interleukin‑10 (IL‑10) single‑nucleotide polymorphism (1082 G/A[rs1800896]) with lifestyle on cardiovascular disease risk in adult Nigerians with type 2 diabetes mellitus(DM). Setting and Design: This case–control study involved patients with type 2 DM with high cardiovascular risk, determined by the Framingham’s classification, and age, sex, and diabetes‑duration matched subjects with low and intermediate cardiovascular risks. Subjects and Methods: The genotypes were detected by polymerase chain reaction (PCR) followed by allelic discrimination using the Applied Biosystems 7900HT Fast Real‑Time PCR System. One‑way analysis of variance and logistic regression were employed for analysis. Odds ratios (ORs) with 95% confidence intervals (CI) were calculated to estimate the risk caused by the polymorphism. P <0.05 was considered significant. Results: The odds for cardiovascular risk decreased progressively in individuals with the GG, GA, and AA genotypes (OR = 0.80, 95% CI = 0.49–1.28, P = 0.345 and OR = 0.46, 95% CI = 0.24–0.88, P = 0.018 for GA and AA genotypes, respectively. A significantly higher proportion of homozygous (AA) individuals were in the low cardiovascular risk group (54.2%, P = 0.018). Compared with the whole study population, individuals with the AA genotype had consistently lower odds for cardiovascular risk in subpopulations like alcohol users (OR = 0.25 [0.11–0.55], P = 0.001), but the odds were higher among smokers (OR = 1.80 [1.14–2.90], P = 0.017) and those with sedentary lifestyles (OR = 2.46, 95% CI = 1.14–5.33, P = 0.024). Conclusions: The homozygous mutant genotype AA of the IL‑10 gene 1082 G/A had a protective effect on cardiovascular risk in type 2 DM. However, this protection was absent in those leading a sedentary lifestyle. [ABSTRACT FROM AUTHOR]
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- 2024
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272. Feasibility and Implementation of a Healthy Lifestyles Program
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Elizabeth Alvarez, Assistant Professor
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- 2022
273. The Role of Place in Person‐ and Family‐Oriented Long‐Term Services and Supports.
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FABIUS, CHANEE D., OKOYE, SAFIYYAH M., WU, MINGCHE M. J., JOPSON, ANDREW D., CHYR, LINDA C., BURGDORF, JULIA G., BALLREICH, JEROMIE, SCERPELLA, DANNY, and WOLFF, JENNIFER L.
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WELL-being ,SOCIAL support ,SOCIAL determinants of health ,PATIENT-centered care ,FAMILY-centered care ,SOCIAL context ,CONCEPTUAL structures ,AGING ,GOVERNMENT policy ,DESCRIPTIVE statistics ,PEOPLE with disabilities ,RESIDENTIAL patterns ,HEALTH equity ,NEEDS assessment ,ADVERSE health care events ,DATA analysis software ,LONG-term health care - Abstract
Policy PointsLittle attention to date has been directed at examining how the long‐term services and supports (LTSS) environmental context affects the health and well‐being of older adults with disabilities.We develop a conceptual framework identifying environmental domains that contribute to LTSS use, care quality, and care experiences.We find the LTSS environment is highly associated with person‐reported care experiences, but the direction of the relationship varies by domain; increased neighborhood social and economic deprivation are highly associated with experiencing adverse consequences due to unmet need, whereas availability and generosity of the health care and social services delivery environment are inversely associated with participation restrictions in valued activities.Policies targeting local and state‐level LTSS‐relevant environmental characteristics stand to improve the health and well‐being of older adults with disabilities, particularly as it relates to adverse consequences due to unmet need and participation restrictions. Context: Long‐term services and supports (LTSS) in the United States are characterized by their patchwork and unequal nature. The lack of generalizable person‐reported information on LTSS care experiences connected to place of community residence has obscured our understanding of inequities and factors that may attenuate them. Methods: We advance a conceptual framework of LTSS‐relevant environmental domains, drawing on newly available data linkages from the 2015 National Health and Aging Trends Study to connect person‐reported care experiences with public use spatial data. We assess relationships between LTSS‐relevant environmental characteristic domains and person‐reported care adverse consequences due to unmet need, participation restrictions, and subjective well‐being for 2,411 older adults with disabilities and for key population subgroups by race, dementia, and Medicaid enrollment status. Findings: We find the LTSS environment is highly associated with person‐reported care experiences, but the direction of the relationship varies by domain. Measures of neighborhood social and economic deprivation (e.g., poverty, public assistance, social cohesion) are highly associated with experiencing adverse consequences due to unmet care needs. Measures of the health care and social services delivery environment (e.g., Medicaid Home and Community‐Based Service Generosity, managed LTSS [MLTSS] presence, average direct care worker wage, availability of paid family leave) are inversely associated with experiencing participation restrictions in valued activities. Select measures of the built and natural environment (e.g., housing affordability) are associated with participation restrictions and lower subjective well‐being. Observed relationships between measures of LTSS‐relevant environmental characteristics and care experiences were generally held in directionality but were attenuated for key subpopulations. Conclusions: We present a framework and analyses describing the variable relationships between LTSS‐relevant environmental factors and person‐reported care experiences. LTSS‐relevant environmental characteristics are differentially relevant to the care experiences of older adults with disabilities. Greater attention should be devoted to strengthening state‐ and community‐based policies and practices that support aging in place. [ABSTRACT FROM AUTHOR]
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- 2023
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274. Mi Gente, Nuestra Salud: Protocol for a People's Movement for Health Ownership.
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Tseng, Marilyn, Espinoza-Kulick, Mario Alberto Viveros, Munoz-Christian, Karen, Gilbert, Irebid, Herrera, Patty, Salazar, Esperanza, Vinchhi, Tejal, Ramirez, Antonio, Martinez, Bernarda, Soto, Gloria, Macedo, Cristina, Kelleher, Anita, Torres, Irma, Perez, Maritza, Diego, Valeria, Gonzalez, Elisa, and Phelan, Suzanne
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PATIENT advocacy ,COMMUNITY-based participatory research ,HEALTH equity ,HUMAN capital ,POWER (Social sciences) - Abstract
Background: Community-based participatory research (CBPR) is an increasingly recognized approach to address health inequities. Although in CBPR all processes occur within the community context, its diagrammatic model places the intervention/research outside of the community rather than conceptualizing it as an event in a complex web of system components. Objectives: We sought to 1) introduce a systems-oriented community ownership conceptual framework that integrates a systems perspective with CBPR and 2) to describe an application of this framework in the form of the Mi Gente, Nuestra Salud initiative, a research-based, action-oriented collaboration between Cal Poly investigators and community partners in Santa Maria and Guadalupe, California. Methods: We conducted a stocktake of community assets and partnerships in Santa Maria and Guadalupe, among California's poorest and most medically underserved cities; created marketing materials; launched the initiative in December 2020; and collected survey and interview data on community health concerns. An advisory board guides direction of the work. Activities are intended to affect partnerships (who is involved in actions and decisions) and processes (what actions will be taken), as well as resources (e.g. building human and social capital by changing narratives of local, historically rooted power dynamics and offering peer learning opportunities on advocacy and health care interactions). Implementation challenges within this framework are also discussed. Conclusions: By de-centering specific interventions and conceptualizing them as single events in a complex web, our system-oriented community ownership model brings the focus back to the system itself, and to system-based processes and solutions, while still guided by CBPR principles. [ABSTRACT FROM AUTHOR]
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- 2023
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275. Asthma disparities among U.S. children and adults.
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Pate, Cynthia A., Qin, Xiaoting, Johnson, Carol, and Zahran, Hatice S.
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ASTHMATICS ,INCOME ,RACE ,ASTHMA ,BACHELOR'S degree ,HEALTH care industry billing - Abstract
Objective: To assess factors that are associated with asthma prevalence and asthma attacks among children (0-17 years) and adults (18 years and over) in the United States of America. Methods: The 2019-2021 National Health Interview Survey data were analyzed using multivariable logistic regression models to determine associations between health outcomes (i.e. current asthma and asthma attacks) and demographic and socioeconomic factors. Each health outcome was regressed over each characteristic variable, adjusting for age, sex, and race/ethnicity for adults and sex and race/ethnicity for children. Results: Asthma was more common among children who were male, blacks, parental education less than bachelor's, or had public health insurance, and among adults who had less than a bachelor's degree, do not own a home, or not in the workforce. Persons in families facing difficulty paying medical bills were more likely to have current asthma (children: aPR = 1.62[1.40-1.88]; adults: aPR = 1.67[1.55-1.81]) and asthma attacks (children: aPR = 1.34[1.15-1.56]; adults: aPR = 1.31[1.20-1.43]). Persons with family income <100% federal poverty threshold (FPT) (children: aPR = 1.39[1.17-1.64]; adults: aPR = 1.64[1.50-1.80]) or adults 100-199% FPT (aPR = 1.28[1.19-1.39]) were more likely to have current asthma. Children and adults with family income <100% FPT and adults 100-199% FPT were also more likely to have asthma attacks. Having asthma attacks was common among adults not in the workforce as well (aPR = 1.17[1.07-1.27]). Conclusions: Asthma affects certain groups disproportionately. The findings of this paper suggesting asthma disparities continue to persist may increase public health programs awareness to better deliver effective and evidence-based interventions. [ABSTRACT FROM AUTHOR]
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- 2023
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276. Pre-pandemic trends and Black:White inequities in life expectancy across the 30 most populous U.S. cities: a population-based study.
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Silva, Abigail, Saiyed, Nazia S., Canty, Emma, and Benjamins, Maureen R.
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LIFE expectancy ,CITIES & towns ,BLACK people ,AMERICAN Community Survey ,BLACK white differences ,DEMOGRAPHIC surveys - Abstract
Background: Racial inequities in life expectancy, driven by structural racism, have been documented at the state and county levels; however, less information is available at the city level where local policy change generally happens. Furthermore, an assessment of life expectancy during the decade preceding COVID-19 provides a point of comparison for life expectancy estimates and trends post COVID-19 as cities recover. Methods: Using National Vital Statistics System mortality data and American Community Survey population estimates, we calculated the average annual city-level life expectancies for the non-Hispanic Black (Black), non-Hispanic White (White), and total populations. We then calculated the absolute difference between the Black and White life expectancies for each of the 30 cities and the U.S. We analyzed trends over four time periods (2008-2010, 2011-2013, 2014-2016, and 2017-2019). Results: In 2017-2019, life expectancies ranged from 72.75 years in Detroit to 83.15 years in San Francisco (compared to 78.29 years for the U.S.). Black life expectancy ranged from 69.94 years in Houston to 79.04 years in New York, while White life expectancy ranged from 75.18 years in Jacksonville to 86.42 years in Washington, DC. Between 2008-2010 and 2017-2019, 17 of the biggest cities experienced a statistically significant improvement in life expectancy, while 9 cities experienced a significant decrease. Black life expectancy increased significantly in 14 cities and the U.S. but decreased significantly in 4 cities. White life expectancy increased significantly in 17 cities and the U.S. but decreased in 8 cities. In 2017-2019, the U.S. and all but one of the big cities had a significantly longer life expectancy for the White population compared to the Black population. There was more than a 13-year difference between Black and White life expectancies in Washington, DC (compared to 4.18 years at the national level). From 2008-2010 to 2017-2019, the racial gap decreased significantly for the U.S. and eight cities, while it increased in seven cities. Conclusion: Urban stakeholders and equity advocates need data on mortality inequities that are aligned with city jurisdictions to help guide the allocation of resources and implementation of interventions. [ABSTRACT FROM AUTHOR]
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- 2023
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277. Advances in the care of breast cancer survivors.
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Cathcart-Rake, Elizabeth J., Tevaarwerk, Amye J., Haddad, Tufia C., D'Andre, Stacy D., and Ruddy, Kathryn J.
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BREAST cancer prognosis ,PREVENTION of drug side effects ,SOCIAL support ,CANCER chemotherapy ,DIGITAL technology ,PHYSICIAN-patient relations ,EVIDENCE-based medicine ,CANCER patients ,CANCER ,HEALTH ,COMMUNICATION ,QUALITY of life ,CANCER patient medical care ,BREAST tumors ,HEALTH promotion - Published
- 2023
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278. How Should Organizations Be Held Accountable for Promoting Environments That Foster Social Connection?
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Deemer, David A., Peavey, Erin K., Teti, Stowe Locke, Hercules, William J., Wong, Jocelyn, and Anderson, Diana C.
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HOME environment ,EVALUATION of medical care ,HEALTH facilities ,SOCIAL support ,SOCIAL networks ,NEGOTIATION ,COMMUNITY health services ,SOCIAL isolation ,INTERPERSONAL relations ,ACCOUNTABLE care organizations ,LONELINESS ,COMMUNITY-based social services ,LONGEVITY ,CORPORATE culture ,SOCIAL responsibility ,BIOETHICS ,PSYCHOLOGICAL resilience - Abstract
Growing familiarity with health risks of loneliness and isolation underscores the importance of social connection in patients' lived environments and communities. Deficits in social connection are linked to poor cognitive, mental, and physical health and premature death. Design interventions for physical environments--structures, spaces, and soundscapes, for example--can foster social connection, support, and resilience. This article canvasses urban interventions that can support human health investment and development. This article also suggests that designers of community policies, programs, structures, and spaces should be accountable for promoting social connection to help generate measurable health outcomes, such as longevity. [ABSTRACT FROM AUTHOR]
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- 2023
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279. Patient enablement and health-related quality of life for patients with chronic back and knee pain: a cross-sectional study in primary care.
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Ng, Amy Pui Pui, Cheng, John King Yiu, Lam, Joyce Sau Mei, Wong, Carlos King Ho, Cheng, Will Ho Gi, Tse, Emily Tsui Yee, Chao, David Vai Kiong, Choi, Edmond Pui Hang, Wong, Rosa Sze Man, and Lam, Cindy Lo Kuen
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BACKACHE ,QUALITY of life ,KNEE pain ,PRIMARY care ,CROSS-sectional method ,CHINESE people - Abstract
Background: Chronic back and knee pain impairs health- related quality of life (HRQoL) and patient enablement can improve HRQoL. Aim: To determine whether enablement was a moderator of the effect of chronic back and knee pain on HRQoL. Design and setting: A cross-sectional study of Chinese patients with chronic back and knee problems in public primary care clinics in Hong Kong. Method: Each participant completed the Chinese Patient Enablement Instrument-2 (PEI-2), the Chinese Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and the Pain Rating Scale (PRS). Multivariable regression examined the effects of PRS score and PEI-2 score on WOMAC total score. A moderation regression model and simple slope analysis were used to evaluate whether the interaction between enablement (PEI-2) and pain (PRS) had a significant effect on HRQoL (WOMAC). Results: Valid patient-reported outcome data from 1306 participants were analysed. PRS score was associated with WOMAC total score (β = 0.326, P<0.001), whereas PEI-2 score was associated inversely with WOMAC total score (β = −0.260, P<0.001) and PRS score. The effect of the interaction between PRS and PEI-2 (PRS × PEI-2) scores on WOMAC total score was significant (β = −0.191, P<0.001) suggesting PEI-2 was a moderator. Simple slope analyses showed that the relationship between PRS and WOMAC was stronger for participants with a low level of PEI-2 (gradient 3.056) than for those with a high level of PEI-2 (gradient 1.746). Conclusion: Patient enablement moderated the impact of pain on HRQoL. A higher level of enablement can lessen impairment in HRQoL associated with chronic back and knee pain. [ABSTRACT FROM AUTHOR]
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- 2023
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280. Comparison of SIREN social needs screening tools and Simplified Omaha System Terms: informing an informatics approach to social determinants of health assessments.
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Holt, Jeana M, Austin, Robin R, Atadja, Rivka, Cole, Marsha, Noonan, Theresa, and Monsen, Karen A
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Objective Numerous studies indicate that the social determinants of health (SDOH), conditions in which people work, play, and learn, account for 30%–55% of health outcomes. Many healthcare and social service organizations seek ways to collect, integrate, and address the SDOH. Informatics solutions such as standardized nursing terminologies may facilitate such goals. In this study, we compared one standardized nursing terminology, the Omaha System, in its consumer-facing form, Simplified Omaha System Terms (SOST), to social needs screening tools identified by the Social Interventions Research and Evaluation Network (SIREN). Materials and Methods Using standard mapping techniques, we mapped 286 items from 15 SDOH screening tools to 335 SOST challenges. The SOST assessment includes 42 concepts across 4 domains. We analyzed the mapping using descriptive statistics and data visualization techniques. Results Of the 286 social needs screening tools items, 282 (98.7%) mapped 429 times to 102 (30.7%) of the 335 SOST challenges from 26 concepts in all domains, most frequently from Income , Home , and Abuse. No single SIREN tool assessed all SDOH items. The 4 items not mapped were related to financial abuse and perceived quality of life. Discussion SOST taxonomically and comprehensively collects SDOH data compared to SIREN tools. This demonstrates the importance of implementing standardized terminologies to reduce ambiguity and ensure the shared meaning of data. Conclusions SOST could be used in clinical informatics solutions for interoperability and health information exchange, including SDOH. Further research is needed to examine consumer perspectives regarding SOST assessment compared to other social needs screening tools. [ABSTRACT FROM AUTHOR]
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- 2023
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281. ASSOCIATION OF METABOLIC STATUS WITH SERUM OREXIN LEVELS IN YOUNG FEMALES.
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Jain, Shikha and Goel, Amit
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BLOOD sugar analysis ,BLOOD pressure ,TRIGLYCERIDES ,BODY weight ,ACADEMIC medical centers ,ANALYSIS of variance ,NEUROPEPTIDES ,ANTHROPOMETRY ,CROSS-sectional method ,INSULIN ,T-test (Statistics) ,PEARSON correlation (Statistics) ,ENZYME-linked immunosorbent assay ,WAIST circumference ,DESCRIPTIVE statistics ,RESEARCH funding ,STATISTICAL sampling ,BODY mass index ,DATA analysis software ,LIPIDS ,WOMEN'S health ,ADULTS - Abstract
Aim- Metabolic fuel detectors regulate energy balance at peripheral and central levels. The aim of this study is to assess association of serum Orexin levels with Metabolic risk markers in women of reproductive age group. Material And Methods- The study was conducted in campus of King George Medical University (KGMU), Uttar Pradesh Lucknow, INDIA. 150 apparently healthy women of reproductive age group i.e. 20-40 years of age were randomly selected. Fasting serum orexin and Serum insulin levels were measured using ELISA and weight, Body mass index, Fasting blood glucose, Lipid prole and Blood pressure were estimated in women. Result- The results show that Serum orexin levels has signicant positive correlation with fasting blood glucose, weight, BMI and waist circumference along with a weak negative correlation with serum Insulin level. Conclusion- In present study Serum orexin levels signicantly correlate with weight, BMI, Fasting blood glucose and weak negative correlation with serum Insulin levels. serum orexin levels did not correlate with lipid prole of women of reproductive age group. [ABSTRACT FROM AUTHOR]
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- 2023
282. Chronic disease outcome metadata from German observational studies – public availability and FAIR principles.
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Schwedhelm, Carolina, Nimptsch, Katharina, Ahrens, Wolfgang, Hasselhorn, Hans Martin, Jöckel, Karl-Heinz, Katzke, Verena, Kluttig, Alexander, Linkohr, Birgit, Mikolajczyk, Rafael, Nöthlings, Ute, Perrar, Ines, Peters, Annette, Schmidt, Carsten O., Schmidt, Börge, Schulze, Matthias B., Stang, Andreas, Zeeb, Hajo, and Pischon, Tobias
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Metadata from epidemiological studies, including chronic disease outcome metadata (CDOM), are important to be findable to allow interpretability and reusability. We propose a comprehensive metadata schema and used it to assess public availability and findability of CDOM from German population-based observational studies participating in the consortium National Research Data Infrastructure for Personal Health Data (NFDI4Health). Additionally, principal investigators from the included studies completed a checklist evaluating consistency with FAIR principles (Findability, Accessibility, Interoperability, Reusability) within their studies. Overall, six of sixteen studies had complete publicly available CDOM. The most frequent CDOM source was scientific publications and the most frequently missing metadata were availability of codes of the International Classification of Diseases, Tenth Revision (ICD-10). Principal investigators’ main perceived barriers for consistency with FAIR principles were limited human and financial resources. Our results reveal that CDOM from German population-based studies have incomplete availability and limited findability. There is a need to make CDOM publicly available in searchable platforms or metadata catalogues to improve their FAIRness, which requires human and financial resources. [ABSTRACT FROM AUTHOR]
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- 2023
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283. Sustaining training effects through physical activity coaching (STEP): a randomized controlled trial.
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Loeckx, Matthias, Rodrigues, Fernanda M., Blondeel, Astrid, Everaerts, Stephanie, Janssens, Wim, Demeyer, Heleen, and Troosters, Thierry
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MEDICAL rehabilitation ,MOBILE apps ,LUNG diseases ,EXERCISE physiology ,PHYSICAL fitness ,PHYSICAL activity ,RANDOMIZED controlled trials ,ACCELEROMETRY ,RESEARCH funding ,QUALITY of life ,DESCRIPTIVE statistics ,OBSTRUCTIVE lung diseases ,STATISTICAL sampling ,TELEMEDICINE - Abstract
Background: Pulmonary rehabilitation (PR) programs improve physical fitness, symptoms and quality of life (QoL) of patients with COPD. However, improved physical activity (PA) is not guaranteed after PR and the clinical benefits fade off after PR discharge. We aimed to investigate whether a 9 months PA-telecoaching program is able to improve PA of patients with COPD, after 3 months of PR and if this leads to maintenance of PR-acquired benefits. Methods: Patients with COPD enrolled in a 6-month PR program were randomized to a (semi-automated) PA-telecoaching program or usual care, 3 months after PR initiation. The intervention consisted of a smartphone application with individual targets and feedback (for 6 months) and self-monitoring with a step counter (for 9 months). Patients were followed up for 9 months after randomization. Primary outcome was PA (daily step count by accelerometery), secondary outcomes were exercise tolerance, quadriceps force, dyspnea and QoL. Results: Seventy-three patients were included (mean ± SD: 65 ± 7 years, FEV
1 49 ± 19%, 6MWD 506 ± 75 m, PA 5225 ± 2646 steps/day). The intervention group presented a significant improvement in steps/day at every visit compared to usual care (between-group differences mean ± SE: 1431 ± 555 steps/day at 9 months after randomization, p = 0.01). Secondary outcomes did not differ between the groups. Conclusion: The semi-automated PA-telecoaching program implemented after 3 months of PR was effective to improve the amount of PA (steps/day) during PR and after follow-up. However, this was not accompanied by the maintenance of other PR-acquired benefits. Trial registration: ClinicalTrials.gov. Identifier: NCT02702791. Retrospectively registered on March 9, 2016. Start study October 2015. https://clinicaltrials.gov/ct2/show/NCT02702791?term=NCT02702791&draw=2&rank=1. [ABSTRACT FROM AUTHOR]- Published
- 2023
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284. An interpretable machine learning model of cross-sectional U.S. county-level obesity prevalence using explainable artificial intelligence.
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Allen, Ben
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MACHINE learning ,ARTIFICIAL intelligence ,HEALTH behavior ,OBESITY ,SEDENTARY behavior - Abstract
Background: There is considerable geographic heterogeneity in obesity prevalence across counties in the United States. Machine learning algorithms accurately predict geographic variation in obesity prevalence, but the models are often uninterpretable and viewed as a black-box. Objective: The goal of this study is to extract knowledge from machine learning models for county-level variation in obesity prevalence. Methods: This study shows the application of explainable artificial intelligence methods to machine learning models of cross-sectional obesity prevalence data collected from 3,142 counties in the United States. County-level features from 7 broad categories: health outcomes, health behaviors, clinical care, social and economic factors, physical environment, demographics, and severe housing conditions. Explainable methods applied to random forest prediction models include feature importance, accumulated local effects, global surrogate decision tree, and local interpretable model-agnostic explanations. Results: The results show that machine learning models explained 79% of the variance in obesity prevalence, with physical inactivity, diabetes, and smoking prevalence being the most important factors in predicting obesity prevalence. Conclusions: Interpretable machine learning models of health behaviors and outcomes provide substantial insight into obesity prevalence variation across counties in the United States. [ABSTRACT FROM AUTHOR]
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- 2023
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285. Drinking and driving among Whites and Hispanics on and off the US/Mexico border in California.
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Caetano, Raul, Vaeth, Patrice A. C., Gruenewald, Paul J., Ponicki, William R., and Kaplan, Zoe
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DRUNK driving ,DRUGGED driving ,AT-risk behavior ,BEVERAGES - Abstract
To examine self-reported rates of driving under the influence (DUI) with and without arrest among border and non-border residents in California. Data were obtained from 1,209 adults 18 to 39 years of age resident in four counties in California: Imperial on the U.S./Mexico border; and Kern, Tulare, and Madera in California's Central Valley. Households were selected using a list assisted sample. Data were collected on the phone or online and analyzed with a heteroskedastic ordinal generalized linear model. Driving after drinking (11.1% vs. 6.5%; q = 0.04) and the lifetime DUI arrest rates were higher for men than women (10.7% vs. 4%; q = 0.001). In multivariable analysis driving after drinking and DUI arrests were not higher on the border, not higher among Hispanics than Whites, and among Hispanics, the rates were not higher among those located on the border. Income was positively associated with drinking and driving. Impulsivity was positively and significantly associated with both drinking and driving and lifetime DUI arrest. The null results suggest that DUI related risk behaviors may not be higher on the border than in other areas of California. There may be health related risk behaviors of higher prevalence in the border population than in other areas, but DUI related behavior may not be one of them. [ABSTRACT FROM AUTHOR]
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- 2023
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286. Composite Indices of Social Determinants of Health: Overview, Measurement Gaps, and Research Priorities for Health Equity.
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Lines, Lisa M., Long, Marque C., Zangeneh, Sahar, DePriest, Kelli, Piontak, Joy, Humphrey, Jamie, and Subramanian, Sujha
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SOCIAL determinants of health ,LIFE expectancy ,MULTIVARIATE analysis ,REGRESSION analysis ,MACHINE learning ,PUBLIC health ,CONCEPTUAL structures ,FACTOR analysis ,HEALTH equity ,POPULATION health ,DATA analysis software ,STATISTICAL correlation - Abstract
The goal of health equity is for all people to have opportunities and resources for optimal health outcomes regardless of their social identities, residence in marginalized communities, and/or experience with oppressive systems. Social determinants of health (SDOH)—the conditions in which we are born, grow, live, work, and age—are inextricably tied to health equity. Advancing health equity thus requires reliable measures of SDOH. In the United States, comprehensive individual-level data on SDOH are difficult to collect, may be inaccurate, and do not capture all dimensions of inequitable outcomes. Individual area-based indicators are widely available, but difficult to use in practice. Numerous area-level composite indices are available to describe SDOH, but there is no consensus on which indices are most appropriate to use. This article presents an analytic taxonomy of currently available SDOH composite indices and compares their components and predictive ability, providing insights into gaps and areas for further research. [ABSTRACT FROM AUTHOR]
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- 2023
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287. Addressing social determinants of health through customization: Quality improvement, telemedicine, and care coordination to serve immigrant families.
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Castillo, Heidi, Locastro, Mary M., Fremion, Ellen, Malhotra, Anjali, Morales, Rosanna, Timmons, Kelly, Jarosz, Susan, Dosa, Nienke P., and Castillo, Jonathan
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IMMIGRANTS ,SOCIAL determinants of health ,LABOR productivity ,SPINA bifida ,WORKFLOW ,QUALITY assurance ,RESEARCH funding ,ELECTRONIC health records ,TELEMEDICINE - Abstract
PURPOSE: The purpose of this project was to establish a pathway for electronic medical record (EMR) customization, utilizing quality improvement methodology, to both identify and address adverse social determinants of health (SDOH) among a diverse spina bifida (SB) population. METHODS: Starting in September 2020, the four fundamental steps were to (1) facilitate an advisory committee to safeguard the standard clinical protocols, (2) characterize barriers to implementation, (3) evaluate workflow to sustain data entry capture, and (4) manage the technology platform for seamless integration. The SB clinic was the first clinic within the enterprise to rollout the use of an adverse SDOH mitigation activity. A Spanish-speaking interpreter was scheduled for all clinics, as many families were limited in English proficiency. RESULTS: The customization of the EMR to support an efficient workflow to address SDOH was feasible in a large and diverse urban medical center. Of the 758 patients served in the clinic, a myelomeningocele diagnosis was present in 86% of individuals. While 52% of participants were female, ethnically 52% of individuals served were Latino. Many of these individuals disclosed being recent immigrants to the United States. Often immigration and asylum related issues were at the forefront of the SDOH issues addressed. CONCLUSION: Given the occurrence of adverse SDOH among individuals with SB, many of whom are new Latin-American immigrants, meaningful clinical efforts are needed to both identify and address the causes of the observed disparities. EMR customization is feasible and can identify and, through social prescriptions, address SDOH to support the provision of safe, high quality, and equitable care for vulnerable and medically complex populations at home and potentially abroad. [ABSTRACT FROM AUTHOR]
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- 2023
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288. Opportunities to optimize lifestyle interventions in combination with glucagon-like peptide-1-based therapy.
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Dash S
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- Humans, Hypoglycemic Agents therapeutic use, Life Style, Combined Modality Therapy, Male, Female, Diabetes Mellitus, Type 2 drug therapy, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 therapy, Glucagon-Like Peptide 1 therapeutic use, Glucagon-Like Peptide 1 agonists, Obesity complications, Obesity therapy, Glucagon-Like Peptide-1 Receptor agonists, Weight Loss drug effects
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Obesity is a chronic multi-system disease and major driver of type 2 diabetes and cardiometabolic disease. Nutritional interventions form the cornerstone of obesity and type 2 diabetes management. Some interventions such as Mediterranean diet can reduce incident cardiovascular disease, probably independently of weight loss. Weight loss of 5% or greater can improve many adiposity-related comorbidities. Although this can be achieved with lifestyle intervention, it is often difficult to sustain in the longer term due to adaptive endocrine changes. In recent years glucagon-like-peptide-1 receptor agonists (GLP-1RAs) have emerged as effective treatments for both type 2 diabetes and obesity. Newer GLP-1RAs can achieve average weight loss of 15% or greater and improve cardiometabolic health. There is heterogeneity in the weight loss response to GLP-1RAs, with a substantial number of patients unable to achieve 5% or greater weight. Weight loss, on average, is lower in older adults, male patients and people with type 2 diabetes. Mechanistic studies are needed to understand the aetiology of this variable response. Gastrointestinal side effects leading to medication discontinuation are a concern with GLP-1RA treatment, based on real-world data. With weight loss of 20% or higher with newer GLP-1RAs, nutritional deficiency and sarcopenia are also potential concerns. Lifestyle interventions that may potentially mitigate the side effects of GLP-1RA treatment and enhance weight loss are discussed here. The efficacy of such interventions awaits confirmation with well-designed randomized controlled trials., (© 2024 The Author(s). Diabetes, Obesity and Metabolism published by John Wiley & Sons Ltd.)
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- 2024
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289. A survey of women diagnosed with breast cancer experiencing oncology treatment-induced hot flushes: identification of specific characteristics as predictors of hot flush occurrence, frequency, and severity.
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Gallagher S, Johnstone A, De Livera A, Marsh DJ, and Walsh S
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Purpose: More women diagnosed with breast cancer (BC) are living with oncology treatment-induced hot flushes (HFs). This Australian-based survey explores why some women experience more severe or ongoing HF and whether specific population characteristics are predictive of HF occurrence, frequency, and/or severity., Methods: A non-probabilistic anonymous survey distributed online (Register4) and two Australian hospitals collected demographic and clinical information. Eligibility was consenting Australian-based women, 18 years and over, with a primary BC diagnosis. Analysis included linear and logistic regression models., Results: A total of 324 survey responses were analyzed. Chemotherapy and hormone therapy were each associated with HF occurrence (aOR = 2.92, 95% CI [1.27, 6.70], p = 0.01; and aOR = 7.50, 95% CI [3.02, 18.62], p < 0.001) and in combination (aOR = 5.98, 95% CI [2.61, 13.69], p < 0.001). Increased self-reported anxiety at BC diagnosis was significantly associated with HF frequency and severity scores (aCO = 0.71, 95% CI [0.31, 1.12], p = 0.001; and aCO = 0.44, 95% CI [0.33, 0.55], p < 0.001). Postmenopausal women had significantly lower HF severity and frequency scores than premenopausal women (aCO = -0.93, 95% CI [-1.62, -0.25], p = 0.008; and aCO = -2.62, 95% CI [-5.14, -0.11], p = 0.041)., Conclusions: Women with BC receiving chemotherapy and/or hormone therapy and premenopausal or experiencing elevated anxiety and/or stress will likely experience more severe oncology treatment-related HFs., Implications for Cancer Survivors: HFs continue across the BC treatment trajectory with women >5-year survivorship still reporting life impacts, with premenopausal women at the time of BC diagnosis at higher risk of experiencing severe and more frequent oncology treatment-induced HFs than postmenopausal women. Women at high risk require information on methods to moderate HF potential life impacts and maintain treatment compliance., (© 2024. The Author(s).)
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- 2024
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290. Improving Health and Reducing Chronic Disease Disparities with Latinx Communities: Evaluating the Role of Documented Community-Based Intervention Participation.
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Boursaw B, FitzGerald CA, Taylor LM, Landrau-Cribbs E, Caswell L, and Cruz TH
- Abstract
Purpose: Limited evidence exists on the impact of participation in community-based chronic disease self-management and prevention programs on health disparities. The purpose of this research was to determine the effects of participation in the Healthy Here Wellness Referral System on existing disparities in glycated hemoglobin (HbA1c), systolic blood pressure (BP), and diastolic BP among Hispanic/Latinx adults compared with non-Hispanic White adults., Methods: We merged administrative clinical and referral data from 2018 through 2022 for adult patients in six focus ZIP codes in New Mexico resulting in a sample of 1331 patients and used regression models to examine predictors of intervention participation as well as propensity-adjusted impacts of participation on HbA1c and BP outcomes., Results: Non-Hispanic White patients who were referred to community-based programming but did not participate saw statistically significant increases in HbA1c. Hispanic/Latinx patients saw statistically significant decreases in HbA1c with referral alone, with no added benefit from program participation. The impact of participation differed statistically significantly (t(683) = 3.55, p < .001) between these two groups for HbA1c levels, as well as for systolic (t(958) = 2.11, p = .04) and diastolic BP outcomes (t(958) = 2.96, p = .003)., Conclusions: Results of this study support the promise of using centralized referral systems to co-produce health improvement in community settings. Mixed findings highlight the need for further uptake of theory-informed measurement in evaluations seeking to understand heterogeneous program impacts by race and ethnicity., (© 2024. W. Montague Cobb-NMA Health Institute.)
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- 2024
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291. Contraceptive strategies for reducing the risk of reproductive cancers.
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Aliabadi AR, Wilailak S, McNally O, Berek JS, and Sridhar A
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- Humans, Female, Ovarian Neoplasms prevention & control, Ovarian Neoplasms epidemiology, Pregnancy, Endometrial Neoplasms prevention & control, Endometrial Neoplasms epidemiology, Gestational Trophoblastic Disease prevention & control, Gestational Trophoblastic Disease epidemiology, Genital Neoplasms, Female prevention & control, Risk Factors, Uterine Cervical Neoplasms prevention & control, Uterine Cervical Neoplasms epidemiology, Contraception methods
- Abstract
Reproductive cancers, encompassing various malignancies like endometrial, ovarian, cervical cancer, and gestational trophoblastic neoplasia, pose a significant global health burden. Understanding their patterns is vital for effective prevention and management. Contraceptives show a protective effect against some of these cancers. This clinical guidance document aims to elucidate the disease burden of reproductive cancers and the evidence supporting contraceptive methods in prevention and management. Regional disparities in incidence and mortality highlight the urgent need for targeted interventions, particularly in low-resource settings. Healthcare providers must weigh individual risk profiles and medical eligibility criteria when discussing contraceptive options. Enhanced health literacy through direct patient education is essential for leveraging low-cost behavioral interventions to mitigate reproductive cancer risks., (© 2024 International Federation of Gynecology and Obstetrics.)
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- 2024
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292. Lessons learned from housing first, rapid rehousing trials with youth experiencing homelessness.
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Slesnick, Natasha, Brakenhoff, Brittany, Bunger, Alicia, Chavez, Laura, Cuthbertson, Caleb, Famelia, Ruri, Feng, Xin, Fitzpatrick, Maggie, Ford, Jodi, Hatsu, Irene, Holowacz, Eugene, Jaderlund, Soren, Kelleher, Kelly, Luthy, Ellison, Mallory, Allen, Martin, Jared, Pizzulo, Alexis, Stone-Sabali, Steven, Yilmazer, Tansel, and Wu, Qiong
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HOMELESSNESS ,SOCIAL problems ,HOUSING ,MENTAL illness ,OLDER people - Abstract
Background: Youth, 18 to 24 years, experiencing homelessness (YEH) are recognized as having developmental challenges dissimilar to older adults. Yet, research on efforts to end homelessness and prevent or intervene in drug use and mental health problems among youth have lagged behind that of adults. The Housing First (HF) Model which underlies Permanent Supportive Housing (PSH) and Rapid Re-Housing (RRH) has become preferred over treatment-first models. Methods and results: We provide an overview of PSH and RRH studies to date and summarize our current understanding of their utility for use with YEH. Finally, we review our team's current and past randomized trials testing RRH with YEH, providing lessons learned and recommendations. Conclusion: Current research efforts to guide best practices are hampered by a lack of fidelity to HF principles, lack of randomized design, and lack of focus on youth. Lessons learned and recommendations from our work are offered to facilitate the future work of those who seek to end homelessness and address drug use and mental health problems among youth. [ABSTRACT FROM AUTHOR]
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- 2023
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293. Current evidence for designing self-management support for underserved populations: an integrative review using the example of diabetes.
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Litchfield, Ian, Barrett, Tim, Hamilton-Shield, Julian, Moore, Theresa, Narendran, Parth, Redwood, Sabi, Searle, Aidan, Uday, Suma, Wheeler, Jess, and Greenfield, Sheila
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DIABETES prevention ,ONLINE information services ,CINAHL database ,MEDICAL databases ,SOCIAL support ,SELF-management (Psychology) ,SYSTEMATIC reviews ,EVIDENCE-based medicine ,MEDICAL care ,HUMAN services programs ,SOCIOECONOMIC factors ,RESEARCH funding ,MEDLINE - Abstract
Aims: With numerous and continuing attempts at adapting diabetes self-management support programmes to better account for underserved populations, its important that the lessons being learned are understood and shared. The work we present here reviews the latest evidence and best practice in designing and embedding culturally and socially sensitive, self-management support programmes. Methods: We explored the literature with regard to four key design considerations of diabetes self-management support programmes: Composition - the design and content of written materials and digital tools and interfaces; Structure - the combination of individual and group sessions, their frequency, and the overall duration of programmes; Facilitators - the combination of individuals used to deliver the programme; and Context – the influence and mitigation of a range of individual, socio-cultural, and environmental factors. Results: We found useful and recent examples of design innovation within a variety of countries and models of health care delivery including Brazil, Mexico, Netherlands, Spain, United Kingdom, and United States of America. Within Composition we confirmed the importance of retaining best practice in creating readily understood written information and intuitive digital interfaces; Structure the need to offer group, individual, and remote learning options in programmes of flexible duration and frequency; Facilitators where the benefits of using culturally concordant peers and community-based providers were described; and finally in Context the need to integrate self-management support programmes within existing health systems, and tailor their various constituent elements according to the language, resources, and beliefs of individuals and their communities. Conclusions: A number of design principles across the four design considerations were identified that together offer a promising means of creating the next generation of self-management support programme more readily accessible for underserved communities. Ultimately, we recommend that the precise configuration should be co-produced by all relevant service and patient stakeholders and its delivery embedded in local health systems. [ABSTRACT FROM AUTHOR]
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- 2023
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294. Reproductive outcomes of water pipe smoking: A scoping review.
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Rostami, Sahar, Fereidouni, Farzane, Maleki-Hajiagha, Arezoo, Motaharinejad, Mohadese, Majidi, Somayye, and Amidi, Fardin
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- 2023
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295. Twenty‐five years of the Medicare Rural Hospital Flexibility Program: The past as prologue.
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Gale, John A.
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RURAL hospitals ,HEALTH policy ,HEALTH services accessibility ,EVALUATION of human services programs ,HOSPITAL emergency services ,RURAL health services ,PATIENT advocacy ,CRITICAL care medicine ,QUALITY of life ,MEDICARE - Abstract
Purpose: The Medicare Rural Hospital Flexibility (Flex) Program and the Critical Access Hospital (CAH) provider type are now 25 years old. Since the inception of the program, the needs of CAHs have evolved greatly. This article describes the history of the limited‐service hospital model that led to the creation of CAHs, the evolution and impact of the Flex Program on CAHs, and the trends likely to impact CAHs and rural healthcare in the future. It concludes with recommendations to address these future needs. Methods: This review of the 25‐year history of the Flex Program and CAHs is based on a detailed analysis of the literature on the limited‐service hospital model and CAHs, the evaluation reports of the Flex Tracking and Flex Monitoring Teams, and the author's 25‐year history with the program. Findings: The Flex Program has made important contributions to the viability of rural hospitals through the conversion of 1,360 CAHs. The program has encouraged attention on CAH quality of care and the role of CAHs in addressing the population health needs of their communities. It has further encouraged the development of a robust rural health policy and advocacy infrastructure that has heightened attention on the needs of rural providers and communities. Conclusions: The needs of CAHs and rural delivery systems have evolved greatly since the implementation of the Flex Program. The 25th anniversary of the program is an ideal time to re‐evaluate and update the program to support CAHs in adapting to the fast‐changing healthcare environment. [ABSTRACT FROM AUTHOR]
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- 2023
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296. A review of excluded groups and non-response in population-based mental health surveys from high-income countries.
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Wright, Eryn, Pagliaro, Claudia, Page, Imogen S., and Diminic, Sandra
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MENTAL health surveys ,HIGH-income countries ,YOUNG adults ,HEALTH facilities ,MENTAL illness - Abstract
National mental health surveys play a critical role in determining the prevalence of mental disorders in a population and informing service planning. However, current surveys have important limitations, including the exclusion of key vulnerable groups and increasing rates of non-response. This review aims to synthesise information on excluded and undersampled groups in national mental health surveys. We conducted a targeted review of nationally representative adult mental health surveys performed between 2005 and 2019 in high-income OECD countries. Sixteen surveys met our inclusion criteria. The response rate for included surveys ranged between 36.3% and 80.0%. The most frequently excluded groups included people who were homeless, people in hospitals or health facilities and people in correctional facilities. Males and young people were the most commonly underrepresented groups among respondents. Attempts to collect data from non-responders and excluded populations were limited, but suggest that mental health status differs among some of these cohorts. The exclusion of key vulnerable groups and high rates of non-response have important implications for interpreting and using the results of national mental health surveys. Targeted supplementary surveys of excluded or hard-to-reach populations, more inclusive sampling methodologies, and strategies aimed at improving response rates should be considered to strengthen the accuracy and usefulness of survey findings. [ABSTRACT FROM AUTHOR]
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- 2023
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297. Falling Behind: The Growing Gap in Life Expectancy Between the United States and Other Countries, 1933–2021.
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Woolf, Steven H.
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LIFE expectancy ,MORTALITY ,WORLD health ,POPULATION geography ,HEALTH status indicators ,COMPARATIVE studies ,DESCRIPTIVE statistics ,TREND analysis - Abstract
Objectives. To document the evolution of the US life expectancy disadvantage and regional variation across the US states. Methods. I obtained life expectancy estimates in 2022 from the United Nations, the Human Mortality Database, and the US Mortality Database, and calculated changes in growth rates, US global position (rank), and state-level trends. Results. Increases in US life expectancy slowed from 1950 to 1954 (0.21 years/annum) and 1955 to 1973 (0.10 years/annum), accelerated from 1974 to 1982 (0.34 years/annum), and progressively deteriorated from 1983 to 2009 (0.15 years/annum), 2010 to 2019 (0.06 years/annum), and 2020 to 2021 (–0.97 years/annum). Other countries experienced faster growth in each phase except 1974 to 1982. During 1933 to 2021, 56 countries on 6 continents surpassed US life expectancy. Growth in US life expectancy was slowest in Midwest and South Central states. Conclusions. The US life expectancy disadvantage began in the 1950s and has steadily worsened over the past 4 decades. Dozens of globally diverse countries have outperformed the United States. Causal factors appear to have been concentrated in the Midwest and South. Public Health Implications. Policies that differentiate the United States from other countries and circumstances associated with the Midwest and South may have contributed. (Am J Public Health. 2023;113(9):970–980. https://doi.org/10.2105/AJPH.2023.307310) [ABSTRACT FROM AUTHOR]
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- 2023
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298. The Role of Primary Care in Advancing Civic Engagement and Health Equity: A Conceptual Framework.
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HABIB, DANIEL R. S., KLEIN, LAUREN M., PERRIN, ELIANA M., PERRIN, ANDREW J., and JOHNSON, SARA B.
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SOCIAL participation ,RACISM ,HEALTH policy ,HEALTH services accessibility ,SOCIAL determinants of health ,SOCIAL change ,HOUSING stability ,VOTING ,PRIMARY health care ,CONCEPTUAL structures ,HEALTH equity ,POVERTY - Abstract
Policy PointsHealth and civic engagement are reciprocally and longitudinally linked: Poor health is associated with less civic engagement. Well‐established social drivers of health and health inequality such as inadequate access to health care, poverty, racism, housing instability, and food insecurity are also drivers of lower civic engagement.A robust primary care system can play a key role in advancing civic engagement (e.g., voting, volunteerism, community service, and political involvement) at the population level but has received little attention.Policy and practice solutions at the individual and structural levels should support and leverage potential synergies among health equity, civic engagement, and primary care. Context: Health and civic engagement are linked. Healthier people may be able to participate more fully in civic life, although those with poorer health may be motivated to address the roots of their health challenges using collective action. In turn, civically active people may experience better health, and societies with more equitable health and health care may experience healthier civic life. Importantly, a robust primary care system is linked to greater health equity. However, the role of primary care in advancing civic engagement has received little study. Methods: We synthesize current literature on the links among health, civic engagement, and primary care. We propose a conceptual framework to advance research and policy on the role of primary care in supporting civic engagement as a means for individuals to actualize their health and civic futures. Findings: Current literature supports relationships between health equity and civic engagement. However, this literature is primarily cross‐sectional and confined to voting. Our integrative conceptual framework highlights the interconnectedness of primary care structures, health equity, and civic engagement and supports the crucial role of primary care in advancing both civic and health outcomes. Primary care is a potentially fruitful setting for cultivating community and individual health and power by supporting social connectedness, self‐efficacy, and collective action. Conclusions: Health and civic engagement are mutually reinforcing. Commonalities between social determinants of health and civic engagement constitute an important convergence for policy, practice, and research. Responsibility for promoting both health and civic engagement is shared by providers, community organizations, educators, and policymakers, as well as democratic and health systems, yet these entities rarely work in concert. Future work can inform policy and practice to bolster primary care as a means for promoting health and civic engagement. [ABSTRACT FROM AUTHOR]
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- 2023
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299. Associations between physical activity patterns and quality of life in persons with type 2 diabetes: A cross sectional study.
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Abonie, Ulric Sena, Ofori ‐ Ampomah, Ama Kissiwaa, Makinyi, Vincent, Addo, Raphael Aseye, and Kumah, Laureen
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TYPE 2 diabetes ,PHYSICAL activity ,MOBILITY of older people ,QUALITY of life ,DISEASE management ,RANK correlation (Statistics) - Abstract
Background: Type 2 diabetes is a major health problem globally and particularly in Ghana. Regular physical activity is important in the management of type 2 diabetes and in improving quality of life of persons with type 2 diabetes. However, there is a lack of data reporting on how physical activity relate to quality of life in persons with diabetes in Ghana. This study explored how physical activity patterns relate to quality of life in persons with type 2 diabetes from a major tertiary hospital in Ghana. Methods: One hundred and twenty-one (121) persons with type 2 diabetes (age, 30–60 years) filled in questionnaires on their physical activity patterns (time spent in sitting, walking, moderate-intensity activities, and vigorous-intensity activities) and quality of life (diabetes control, anxiety and worry, social burden, sexual functioning, energy and mobility). The relationships between the variables were examined using spearman correlation. Results: Time spent in sitting, walking, moderate-intensity activities and vigorous-intensity activities were 1677.7±401.5min, 464.1±296.0MET-min, 241.2±65.8MET-min and 1956.5±1251.0MET-min respectively. Walking was negatively related to energy and mobility (r = -.48, p<0.01), sexual functioning (r = -0.44, p<0.01), social burden (r = -0.41, p<0.01) and diabetes control (r = -0.56, p<0.01) domains of quality of life. Vigorous-intensity activities was negatively related to anxiety and worry (r = -0.20, p<0.05). Conclusions: The results suggests that persons with type 2 diabetes who experience decline in energy and mobility, sexual functioning, and disease management, and heightened social burden, anxiety and worry may benefit from guidance on optimal physical activity behaviour in the form of walking to improve their quality of life. [ABSTRACT FROM AUTHOR]
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- 2023
- Full Text
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300. Impact of health disparities on national breast cancer screening participation rates in South Korea.
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Nari, Fatima, Park, Juwon, Kim, Nayeon, Kim, Dong Jin, Jun, Jae Kwan, Choi, Kui Son, and Suh, Mina
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EARLY detection of cancer ,BREAST cancer ,HEALTH equity ,SOCIOECONOMIC disparities in health ,PARTICIPATION ,KOREANS - Abstract
Socioeconomic barriers to cancer screening exist at a regional level. The deprivation index is used to estimate socioeconomic gradients and health disparities across different geographical regions. We aimed to examine the impact of deprivation on breast cancer screening participation rates among South Korean women. Municipal breast cancer screening participation rates in women were extracted from the National Cancer Screening Information System and linked to the Korean version of the deprivation index constructed by the Korea Institute for Health and Social Affairs. A generalised linear mixed model was employed to investigate the association between the deprivation index and age-standardised breast cancer screening participation rates in 2005, 2012, and 2018. Participation rates increased gradually across all age groups from 2005 to 2018. Participants in their 60 s consistently had one of the highest participation rates (2005: 30.37%, 2012: 61.57%, 2018: 65.88%). In 2005, the most deprived quintile had a higher estimate of breast cancer screening participation than the least deprived quintile (2nd quintile; estimate: 1.044, p = 0.242, 3rd quintile; estimate: 1.153, p = 0.192, 4th quintile; estimate: 3.517, p = 0.001, 5th quintile; estimate: 6.913, p = < 0.0001). In 2012, the participation rate also increased as the level of deprivation increased. There were no statistically meaningful results in 2018. Regions with high deprivation have a higher participation rate in breast cancer screening. The role of health disparities in determining cancer outcomes among women in Korea requires further examination. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
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