266 results on '"Oliviero, M"'
Search Results
252. Lessons on dermoscopy #4. Poorly defined pigmented lesion. Diagnosis: pigmented BCC.
- Author
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Wang SQ, Katz B, Rabinovitz H, Kopf AW, and Oliviero M
- Subjects
- Aged, Carcinoma, Basal Cell diagnosis, Female, Forehead, Humans, Skin Neoplasms diagnosis, Carcinoma, Basal Cell pathology, Skin Neoplasms pathology
- Published
- 2000
- Full Text
- View/download PDF
253. Lessons on dermoscopy. Compound congenital melanocytic nevus.
- Author
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Wang SQ, Katz B, Rabinovitz H, Kopf AW, and Oliviero M
- Subjects
- Adolescent, Diagnosis, Differential, Female, Humans, Nevus, Pigmented congenital, Nevus, Pigmented pathology, Skin Neoplasms congenital, Skin Neoplasms pathology, Nevus, Pigmented diagnosis, Skin Neoplasms diagnosis
- Published
- 2000
- Full Text
- View/download PDF
254. Lessons on dermoscopy. Diagnosis: seborrheic keratosis.
- Author
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Wang SQ, Katz B, Rabinovitz H, Kopf AW, and Oliviero M
- Subjects
- Aged, Diagnosis, Differential, Female, Humans, Keratosis, Seborrheic pathology, Melanoma diagnosis, Skin Neoplasms diagnosis, Keratosis, Seborrheic diagnosis
- Published
- 2000
- Full Text
- View/download PDF
255. Lessons on dermoscopy. Diagnosis: dysplastic nevus (so-called Clark nevus).
- Author
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Wang SQ, Katz B, Rabinovitz H, Kopf AW, and Oliviero M
- Subjects
- Back, Humans, Male, Middle Aged, Dysplastic Nevus Syndrome pathology
- Published
- 2000
- Full Text
- View/download PDF
256. Melanoma in a psoriatic plaque.
- Author
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Tran N, Rabinovitz HS, Oliviero M, and Kopf A
- Subjects
- Humans, Male, Melanoma pathology, Middle Aged, Psoriasis pathology, Skin Neoplasms pathology, Melanoma complications, Psoriasis complications, Skin Neoplasms complications
- Abstract
This is the first reported case of a melanoma in a psoriatic plaque. The clinical, dermoscopic, and histologic features of this case are detailed. A review of the risk of melanoma among patients treated with psoralen-ultraviolet A is presented.
- Published
- 2000
257. Spitz nevus: a case report.
- Author
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Hauptman G, Kopf A, Rabinovitz H, Oliviero M, and Rao B
- Subjects
- Adult, Female, Humans, Nevus, Pigmented pathology, Skin Neoplasms pathology
- Abstract
The case of a 2-mm Spitz nevus is reported. We comment on the case and describe the skin-surface microscopy features.
- Published
- 1999
258. The actinic comedonal plaque.
- Author
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Hauptman G, Kopf A, Rabinovitz HS, Oliviero M, and Rivlin D
- Subjects
- Acne Vulgaris etiology, Acne Vulgaris metabolism, Acne Vulgaris pathology, Aged, Carcinoma, Basal Cell complications, Diagnosis, Differential, Facial Dermatoses etiology, Facial Dermatoses metabolism, Humans, Keratins metabolism, Male, Photosensitivity Disorders complications, Skin metabolism, Skin pathology, Skin Neoplasms diagnosis, Acne Vulgaris diagnosis, Facial Dermatoses diagnosis
- Abstract
A case of actinic comedonal plaque is reported. We comment on the case as well as describe the skin surface microscopic features.
- Published
- 1997
259. [A query system for the "SINTESI" database in scientific research and medical practice].
- Author
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Palmieri V, Crivaro M, Tammaro P, Oliviero M, Bianco A, Dormi A, Pasquarelli V, Gaddi A, and Celentano A
- Subjects
- Humans, Cardiovascular Diseases physiopathology, Cardiovascular Diseases therapy, Database Management Systems, Databases, Factual
- Abstract
"SINTESI release 1.0" is an application for Windows that was designed to enable a practical approach to day-hospital evaluation and management of several metabolic and instrumental parameters. "SINTESI" provides electronic archives such as demographics, history, follow-up, laboratory, electrocardiogram, Doppler echocardiography, vascular echo-Doppler, Holter ECG, nuclear imaging, radiology, ergometric testing, ambulatory blood pressure monitoring, hemodynamics. We have improved the first release (1.0) with a new application that queries the database ("SINTESI release 2.0"). The new query application, developed in collaboration with experts of the Italian Group for the Study of Atherosclerosis and Metabolic Diseases, was designed with the central file displaying buttons that recall electronic archives, allowing to select the variables for the query. At the end of each operation, the user always returns to the central file, where it builds the query formula by "AND/OR" logic operators. Query formula and results can be recorded to be used whenever needed. The results of the query can be exported as DBF or ASCII files for analysis with statistical packages. This feature allows the use of the data bank for medical research.
- Published
- 1997
260. Globulelike dermoscopic structures in pigmented seborrheic keratosis.
- Author
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Provost N, Kopf AW, Rabinovitz HS, Oliviero MC, Toussaint S, and Kamino HH
- Subjects
- Humans, Keratosis, Seborrheic complications, Microscopy, Pigmentation Disorders complications, Keratosis, Seborrheic pathology, Pigmentation Disorders pathology
- Published
- 1997
- Full Text
- View/download PDF
261. [Absence of an association of the D allele of the ACE gene with arterial pressure in mild-moderate essential arterial hypertension].
- Author
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Celentano A, Mancini FP, Crivaro M, Palmieri V, Tammaro P, De Stefano V, Oliviero M, Di Palma Esposito N, Pietropaolo I, Tufano A, Di Minno G, and de Divitiis O
- Subjects
- Adult, Aged, Blood Pressure physiology, Blood Pressure Monitoring, Ambulatory, Female, Genotype, Humans, Hypertension enzymology, Male, Middle Aged, Alleles, Hypertension genetics, Peptidyl-Dipeptidase A genetics, Polymorphism, Genetic genetics
- Abstract
To assess the relationship between the angiotensin converting enzyme (ACE) gene I/D polymorphism, blood pressure (BP) and family history of hypertension, 133 hypertensive subjects (mean age 50 +/- 9 years, 78 males, 55 females) were selected according to both casual supine BP > 140/90 mmHg and ambulatory BP > 134/88 mmHg. Drug treatment was discontinued 2 weeks before entering the study. Subjects with myocardial ischemia, as well as those with "white coat" hypertension, were excluded. The study population was subclassified according to age < or = 50 years. Polymerase chain reaction was used to detect the I/D polymorphism of the ACE gene, and the DD genotype was analysed twice. The frequencies of the I and D allele were 42 and 58%, and the distribution of the ID+ II and DD genotypes were 69 and 31% respectively. No significant relation was found among ACE genotypes (DD vs ID+ II) and casual systolic or diastolic BP as well as ambulatory BP, both in the whole study population and in the subpopulation < 50 years old. No difference was found also in the distribution of dippers and no dippers, as well as in the distribution of subjects with a positive family history in the whole sample and hypertensives < 50 years old.
- Published
- 1996
262. Expression of Met/hepatocyte growth factor receptor gene and malignant behavior of musculoskeletal tumors.
- Author
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Scotlandi K, Baldini N, Oliviero M, Di Renzo MF, Martano M, Serra M, Manara MC, Comoglio PM, and Ferracini R
- Subjects
- Adolescent, Adult, Aged, Blotting, Western, Bone Neoplasms chemistry, Bone Neoplasms genetics, Bone Neoplasms pathology, Child, Female, Humans, Immunohistochemistry, Male, Middle Aged, Muscle Neoplasms chemistry, Muscle Neoplasms genetics, Muscle Neoplasms pathology, Proto-Oncogene Mas, Proto-Oncogene Proteins c-met, Receptor Protein-Tyrosine Kinases analysis, Receptor Protein-Tyrosine Kinases genetics, Bone Neoplasms metabolism, Muscle Neoplasms metabolism, Receptor Protein-Tyrosine Kinases metabolism
- Abstract
Overexpression of the hepatocyte growth factor receptor (Met/HGF receptor), a transmembrane tyrosine kinase encoded by the met proto-oncogene, has been associated with tumor progression in different human carcinomas. More recently, the Met/HGF receptor has also been described in tumor cell lines of mesenchymal origin, suggesting the existence of an autocrine loop that may contribute to the pathogenesis of sarcomas. In this study, we analyzed the expression of Met/HGF receptor by Western blotting and immunohistochemistry in frozen samples of 87 primary tumors of bone and soft tissues. Among benign tumors, overexpression was consistently found only in giant-cell tumor, a locally aggressive lesion that may also, although rarely, spread to the lung. Among malignant lesions, the presence of the Met/HGF receptor was detected in a relevant percentage of primaries and in almost all of the recurrences. The highest levels of Met/HGF receptor were found in osteosarcoma, a highly aggressive tumor that typically permeates the host bone and rapidly expands to the soft tissues. On the contrary, only low levels of Met/HGF receptor were found in chondrosarcoma, a slowly growing tumor that usually expands without massive destruction of the surrounding structures. These data indicate an association of Met/HGF expression with local aggressiveness in human mesenchymal tumors. The finding of Met/HGF receptor overexpression in all of the osteosarcomas suggests a role for the met proto-oncogene in the pathogenesis of this tumor.
- Published
- 1996
263. Anti-hypertensive effect of manidipine: 24 hours monitoring evaluation and Doppler-echocardiographic remarks.
- Author
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Celentano A, Crivaro M, Perticone F, Palmieri V, Oliviero M, Tammaro P, Pietropaolo I, Di Palma Esposito N, Cloro C, Cosco C, Mattioli PL, and De Divitiis O
- Subjects
- Adult, Aged, Blood Pressure Monitoring, Ambulatory, Female, Humans, Hypertension diagnostic imaging, Hypertension physiopathology, Male, Middle Aged, Nitrobenzenes, Piperazines, Ultrasonography, Doppler, Blood Pressure drug effects, Calcium Channel Blockers administration & dosage, Dihydropyridines administration & dosage, Hypertension drug therapy
- Abstract
In order to evaluate the antihypertensive effects of manidipine, at the dosage of 10 or 20 mg once daily, we studied 36 patients (12 males and 24 females, mean age 54.3 years) with mild hypertension. After a wash-out period of 2 weeks and another 2 week run-in period with placebo, all the patients were assigned to a treatment with manidipine 10 mg/ day. After 2 weeks of treatment, the non-normalized (diastolic BP > 90 mmHg) and the non-responders (BP fall < 10 mmHg) received an increase in dosage to 20 mg/day. The drug effects were assessed by casual blood pressure (BP) measurement at baseline and after 4, 8, 12, 24, 36 and 52 weeks. At baseline and after 1 year of treatment a 24-h BP monitoring and a Doppler echocardiogram were performed. Routine laboratory tests were performed at baseline, after 6 months and after 1 year of treatment. At the end of the observation period, both casual systolic (p < 0.01) and diastolic (p < 0.001) BP were significantly reduced; 24-h BP monitoring showed a significant decrease in systolic (p < 0.05) and diastolic (p < 0.01) pressure, systolic and diastolic (p < 0.001) daytime and night-time measurements. The peak to through ratio was 67%. No difference was found in heart rate. Reduced interventricular septum thickness (p < 0.05), increased fractional shortening (p < 0.02), reduced end-systolic stress (p < 0.005) and systemic vascular resistances (p < 0.001), and lower values of atrial filling fraction (AFF) (p < 0.001) after 1 year of treatment have been shown at the Doppler-Echo evaluation. A multilinear regression analysis showed a relation between delta %AFF and delta %24-h systolic BP (R = 0.74; F = 7.5: p < 0.05) and with delta % daytime systolic BP (R = 0.77; F = 9.2; p < 0.02). No abnormal changes were observed in laboratory tests. Three non-responder patients and three patients with adverse effects (1 flushing and 2 ankle oedema) dropped out and were excluded from the final analysis. In conclusion, manidipine at an individualized dose of 10 or 20 mg. was effective and safe in the management of arterial hypertension. Hemodynamic evaluations after 1 year of treatment confirmed an improvement of systolic and diastolic function, with an evident reduction of afterload.
- Published
- 1996
264. [The SINTESI Project: software in cardiovascular prevention].
- Author
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Celentano A, Palmieri V, Tammaro P, Crivaro M, Oliviero M, Pietropaolo I, Pasquarelli V, Gaddi A, and de Divitiis O
- Subjects
- Adult, Cardiovascular Diseases diagnosis, Female, Humans, Italy, Male, Risk Factors, User-Computer Interface, Cardiovascular Diseases prevention & control, Databases, Factual, Software
- Abstract
Coronary heart disease is the most important cause of mortality in adults. New approaches may reduce the cardiovascular risk in population. "SINTESI" is an original data base designed in collaboration with the Italian Group for the Study of Metabolism Disease and Atherosclerosis to improve the evaluation of the major risk factors in the population and to create a data bank for medical research. It runs in Windows. The software includes the following electronics archives: Demographics; History; Follow-up; ECG; Laboratory; Doppler-echocardiography; Stress test-ECT; Ambulatory blood pressure monitoring; Holter-ECG; Nuclear imaging; Vascular echo-Doppler; Hemodynamics; Radiology. We named the most important file "Main Working Area" (MWA). This displays all the most important information on the clinical status of the patients and represents the "console" for using the software. In fact, in MWA "buttons" are displayed to enter all the electronic archives. The software displays graphics and the flow-chart of clinical history. We implemented "routines" for automatic evaluation of several variables. We also simplify the statistical use of the data implementing functions for "query" that permit the management of data bank. The use of this software may facilitate the correct evaluation and stratification of the cardiovascular risk. In conclusion, "Progetto SINTESI" is an easy, synthetic organization of patient's clinical data and a complete data bank. It is our opinion that the use of this software may promote a standard way of collecting a large number of data to improve the stratification of cardiovascular risk.
- Published
- 1995
265. Reduction of left ventricular mass by short-term antihypertensive treatment with isradipine: a double-blind comparison with enalapril.
- Author
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Galderisi M, Celentano A, Garofalo M, Tammaro P, Oliviero M, Petrocelli A, and de Divitiis O
- Subjects
- Blood Pressure drug effects, Double-Blind Method, Echocardiography, Doppler, Female, Humans, Hypertension complications, Hypertrophy, Left Ventricular complications, Hypertrophy, Left Ventricular pathology, Male, Middle Aged, Ventricular Function, Left drug effects, Antihypertensive Agents therapeutic use, Enalapril therapeutic use, Hypertension drug therapy, Hypertrophy, Left Ventricular drug therapy, Isradipine therapeutic use
- Abstract
The aim of the present study was to evaluate the effect of dihydropyridine calcium antagonist isradipine on left ventricular (LV) structure and function in patients with essential hypertension. Cuff blood pressure and Doppler echocardiographic variables were assessed in 26 patients with mild to moderate hypertension (diastolic blood pressure range 95-110 mmHg) before and after 12 weeks of therapy with either isradipine 5 mg daily or enalapril 20 mg daily. The study was of double-blind, parallel design, with a placebo run-in period of 15 days. Three subjects withdrew from isradipine treatment because of flushing and 2 from enalapril treatment due to cough before completing the study. Both drugs significantly reduced cuff systolic and diastolic blood pressure (p < 0.001) without affecting heart rate. By virtue of the decrease in both septal wall (p < 0.01) and posterior wall thicknesses (p < 0.05), isradipine treatment produced a significant reduction in LV mass adjusted for height (p < 0.001) in comparison with placebo; also LV end-systolic dimension showed a slight decrease (p < 0.05). Enalapril induced a similar reduction in LV end-systolic dimension (p < 0.05) but the changes of wall thickness and LV mass did not reach statistical significance. In conclusion, our results indicate that isradipine treatment improves LV systolic function and causes a significant reduction in LV mass. This reduction is observed early in the course of antihypertensive treatment and is effective in both patients with and without LV hypertrophy.
- Published
- 1994
266. First exchange neutrophilia is not always an index of peritonitis during CAPD.
- Author
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Strippoli P, Coviello F, Orbello G, Mingrone G, DiMaggio A, Carelli AM, Oliviero MR, Sebastio AM, and Scatizzi A
- Subjects
- Adult, Aged, Aged, 80 and over, Female, Humans, Leukocyte Count, Male, Middle Aged, Peritonitis etiology, Prospective Studies, Dialysis Solutions, Neutrophils, Peritoneal Dialysis, Continuous Ambulatory adverse effects, Peritonitis diagnosis
- Abstract
To date, the medical literature suggests that CAPD patients with peritonitis have an increase in the dialysate white cell count (greater than 100 cells mL) with neutrophilia (greater than 50%). In order to explore the differential composition of the peritoneal fluid cells (P.F.C.), we have followed 21 patients (PTS) twice a month over a 30-month period. Nine hundred and fifty samples obtained either from the 24 hours (hrs) drained CAPD fluid, or from the "First Morning Exchange" (F.M.E.) during the same day, when possible, were estimated with the "Millipore Filter" (5-8 Micron (lw) pore size), stained by the Papanicolau method. The results can be so summarized: (1) 13 PTS (62%) showed constantly a low polynuclear count (3-32%); (2) 8 non-infected PTS (38%) showed constantly a higher neutrophilia (40-80%); and (3) from time to time the PTS of the two groups showed a higher neutrophilia and an increased cellularity during clinical infection. In all the samples, the differential P.F.C. count was not affected by the dialysate composition and no difference was observed between the 24 hrs samples and the F.M.E. samples made on the same day. Differential peritoneal cell count may be useful when there are important changes in the stable individual composition.
- Published
- 1989
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