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1,554 results on '"Nappi, C"'

251. [Prevention of postoperative abdominal adhesions in gynecological surgery. Consensus paper of an Italian gynecologists' task force on adhesions]

Author

Mais, V, Angioli, R, Coccia, E, Fagotti, Anna, Landi, S, Melis, Gb, Pellicano, M, Scambia, Giovanni, Zupi, E, Angioni, S, Arena, Selena, Corona, R, Fanfani, Francesco, Nappi, C., Fagotti, Anna (ORCID:0000-0001-5579-335X), Scambia, Giovanni (ORCID:0000-0003-2758-1063), Fanfani, Francesco (ORCID:0000-0003-1991-7284), Mais, V, Angioli, R, Coccia, E, Fagotti, Anna, Landi, S, Melis, Gb, Pellicano, M, Scambia, Giovanni, Zupi, E, Angioni, S, Arena, Selena, Corona, R, Fanfani, Francesco, Nappi, C., Fagotti, Anna (ORCID:0000-0001-5579-335X), Scambia, Giovanni (ORCID:0000-0003-2758-1063), and Fanfani, Francesco (ORCID:0000-0003-1991-7284)

Abstract

Adhesions are the most frequent complication of abdominopelvic surgery, causing important short- and long-term problems, including infertility, chronic pelvic pain and a lifetime risk of small bowel obstruction. They also complicate future surgery with considerable morbidity and expense, and an important mortality risk. They pose serious quality of life issues for many patients with associated social and healthcare costs. Despite advances in surgical techniques, the healthcare burden of adhesion-related complications has not changed in recent years. Adhesiolysis remains the main treatment although adhesions reform in most patients. There is rising evidence, however, that surgeons can take important steps to reduce the impact of adhesions. A task force of Italian gynecologists with a specialist interest in adhesions having reviewed the current evidence on adhesions and considered the opportunities to reduce adhesions in Italy, have approved a collective consensus position. This consensus paper provides a comprehensive overview of adhesions and their consequences and practical proposals for actions that gynecological surgeons in Italy should take. As well as improvements in surgical technique, developments in adhesion-reduction strategies and new agents offer a realistic possibility of reducing adhesion formation and improving outcomes for patients. They should be adopted particularly in high risk surgery and in patients with adhesiogenic conditions. Patients also need to be better informed of the risks of adhesions.

Published
2011

252. Tibolone as 'add-back therapy' in uterine leiomyomatosis

Author

Palomba, S, Affinito, P, Sammartino, A, Santangelo, N, Tremolaterra, F, Di Spiezio Sardo, A, Risorto, D, Nappi, C, Palomba, S, Affinito, P, Sammartino, A, Santangelo, N, Tremolaterra, F, DI SPIEZIO SARDO, Attilio, Risorto, D, and Nappi, Carmine

Published
1999

256. The effect of menopause on blood lipid and lipoprotein levels

Author

de aloysio, D, Gambacciani, M, Meschia, M, Pansini, F, Bacchi Modena, A, Bolis, Pf, Massobrio, M, Maiocchi, G, Peruzzi, E, Nencioni, T, Ciammella, M, Bonaccorsi, G, Morano, D, Viglino, S, Artoni, G, Grassini, E, Radici, G, De Cicco, F, Ronsisvalle, E, Marcacci, B, Perrone, P, De PAoli, D, Colacurci, N, De Franciscis, P, Lodico, G, Ferreri, R, Loizzi, V, Giacomelli, P, Benetello, E, Salmaggi, P, Coniglio, E, Giussani, E, Comi, R, Grimaldi, E, Mangino, Fp, Bucciantini, S, Checcucci, V, Nappi, C, Affinito, P, Campagnoli, C, Lanza, M, Galbiati, G, Albini, D, Lentini, G, Civallelci, S, Galbignani, E, Franchi, M, Terreni, Mg, Cicoli, C, Pulisca, S, Chionna, R, Marabini, R, Cordopatri, A, Spadaro, I, Cagnacci, Angelo, Volpe, A, De Leo, V, La MArca, A, Camanni, F, Manieri, C, Scognamiglio, P, Romani, L, Cargiaghe, S, Mannu, L, Masi, P, Fattorini, G, Bersellini, B, Bianicotti, L, Marchesoni, D, Dal Pozzo, M, Ramazzotto, F, Stegher, C, Molteni, B, Molteni, E, Lombardo, R, Galati, G, Sironi, A, Ranchet, G, Belloni, C, Proietti, C, Lorefice, R, Menozzi, G, Carunchio, P, Rovetta, E, Gallo, M, De Luigi, G, Righetti, G, Favaro, P, Gentile, E, Flangini, O, De Stefani, L, Sciacchitano, Sg, Catrini, R, Bartiromo, F, Bruno, M, Puggioni, Gf, Sionis, L, Agostinelli, D, Tajani, E, Mercuri, G, and Petronio, P.

Subjects
Menopause, Lipid, Cholesterol
Published
1999

260. Ultrasonographic measurement of endometrial thickness during hormonal replacement therapy in postmenopausal women

Author

Affinito, P, Palomba, S, Pellicano, M, Sorrentino, C, Di Carlo, C, Morgera, R, Arienzo, Mp, Nappi, C., Affinito, P, Palomba, S, Pellicano, Massimiliano, Sorrentino, C, DI CARLO, Costantino, Morgera, R, Arienzo, Mp, and Nappi, Carmine

Subjects
Dose-Response Relationship, Drug, Estradiol, Progesterone Congeners, Biopsy, Needle, Estrogen Replacement Therapy, menopause, Medrogestone, Middle Aged, Sensitivity and Specificity, Drug Administration Schedule, Postmenopause, hormone replacement therapy, Endometrium, transvaginal sonography, Vagina, endometrium, Humans, Female, Ultrasonography
Abstract

The objective of this study was to measure endometrial thickness by transvaginal ultrasonography during two regimens of hormonal replacement therapy (HRT) in postmenopausal women and to compare these data with endometrial histology. Transvaginal ultrasonographic evaluation of endometrial thickness and endometrial biopsy were performed in 80 postmenopausal women before and after 6 months of HRT (between the 24th and the 28th day of the cycle). The group was randomized so that 40 women (Group A) were treated with a continuous sequential regimen consisting of 5 micrograms/day of estradiol continuously and 5 mg/day of medrogestone from the 17th to the 28th day of the cycle; and 40 women (Group B) were given continuous administration of 50 micrograms/day estradiol and 5 mg/day medrogestone. Prior to therapy, there was no significant difference in mean endometrial thickness between the groups. After 6 months of therapy, endometrial thickness was significantly increased in comparison with basal values in both groups. The mean value was significantly higher (p0.001) in Group A (8.5 +/- 3.7 mm) than in Group B (3.6 +/- 1.3 mm). In Group A, endometrial thickness wasor = 4 mm in 16.7% of patients andor = 8 mm in 69.5% of patients. In Group B, 91% of patients had an endometrium ofor = 4 mm. In both groups, the thickness of the atrophic endometrium was less than that of the other histological types of endometrium (4.1 +/- 0.3 mm for Group A and 3.5 +/- 1.2 mm for Group B). In Group A, the difference in mean endometrial thickness between the proliferative and secretory endometrium was not statistically significant. In both groups, the transvaginal ultrasonographic measurement of endometrial thickness ofor = 4 mm had a high sensitivity for detecting atrophic endometrium (83.3% for Group A and 93.7% for Group B).

Published
1998

266. Trial-based cost-effectiveness of abatacept for rheumatoid arthritis patients in Italy.

Author

Gaultney, J, Benucci, M, Iannazzo, S, Nappi, C, Sion, K, Sabater, FJ, and Sabater, F J

Abstract

Introduction: Rheumatoid arthritis (RA) is a chronic, inflammatory disorder leading to disability and reduced quality of life. Effective treatment is a significant economic burden on the Italian healthcare system. Economic models in RA are commonly based on indirect treatment comparisons.Methods: This study assessed the cost-effectiveness of abatacept relative to adalimumab for RA in Italy based on a head-to-head trial by means of a cost-consequence analysis.Results: Health benefits based on the most stringent efficacy criteria were in favor of abatacept compared to adalimumab. Rates for more costly adverse events were higher for adalimumab compared to abatacept, which was reflected in the lower costs for abatacept (-€237,246 or -€237per patient).Conclusion: The health economic value of abatacept compared with adalimumab from the perspective of the Italian NHS depends on the choice of health outcome. Health gains with abatacept were generally based on more stringent criteria and lower total costs. [ABSTRACT FROM AUTHOR]

Published
2016
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269. Effects of HRT on ocular function

Author

Affinito, P., Mattace Raso, F, Palomba, S, Merlino, P, Loffredo, A, Loffredo, M, Arienzo, Mp, and Nappi, C

Published
1997

273. Sindrome urogenitale ed estriolo

Author

Nappi, C, Affinito, P, Palomba, S, Sorrentino, C, Savarese, F, Moccia, Gf, Napolitano, V, and Mattace-Raso, F

Published
1996

282. The skin in menopause

Author

Nappi, C, Affinito, P, Di Carlo, C, Sorrentino, C, Palomba, S, and Cimini, V

Published
1995

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