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863 results on '"Merrill L"'

251. Geometry-Dependent Displacement Current in the Pulsed-Townsend Drift Tube

Author

Merrill L. Andrews, David Ramos, E. L. Patrick, Douglas Abner, and Alan Garscadden

Subjects
Physics, Physics::Instrumentation and Detectors, Method of images, Point particle, Displacement current, law, Electric field, Biasing, Geometry, Boundary value problem, Cathode, Anode, law.invention
Abstract

The method of images was used to determine the displacement current as a function of distance for the case of a point charge approaching a guarded anode of finite size. The analysis was extended to include the effect of an adjacent cathode as a boundary condition. This has produced a simplified model for the current response of a pulsed-Townsend drift tube as a function of the drift-tube geometry. Sources of error are presented that can arise purely from the drift tube geometry even when guard rings are used to establish a uniform electric field. However, these effects occur regardless of the uniformity of the field supplied by the drift-space bias voltage. The results of the model agree well with experimental mobility data obtained by the authors. The analysis also explains the origin of peculiarities in the current transients recorded in some previous pulsed-Townsend experiments.

Published
1990

252. A Monte Carlo Simulation Of Electron Drift Limited By Collisions In Gas Mixtures Using The Null Collision Method

Author

Merrill L. Andrews, E. L. Patrick, David Ramos, Alan Garscadden, and Douglas Abner

Subjects
Physics, Cross section (physics), Time of flight, Position (vector), Monte Carlo method, Null (mathematics), Dynamic Monte Carlo method, Statistical physics, Collision, Boltzmann equation
Abstract

The Monte Carlo method is explored as an alternative to expansion solutions of the Boltzmann transport equation for determining electron swarm parameters. This method uses the probability P that the time of flight of an electron is less or equal to some time T, and the time T. The null collision method proposed by Skullerud (1968) and developed in detail by Reid (1979) takes advantage of the simple relationship between the time of flight T and the probability of having a collision P for a cross section that is inversely proportional to the velocity. A null collision cross section is added to real cross sections so as to impose this relation. Once the time of flight is established, then the position and the energy of the electron are also defined. A new random number R is generated to determine which type of collision event takes place. When two gases are present in the simulation the following conditions determine the type of collision that takes place.

Published
1990

259. U.S. Navy Women's Satisfaction With Obstetric and Gynecologic Medical Care.

Author

NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA, Burr, R. G., Merrill, L. L., Emens-Hesslink, K., NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA, Burr, R. G., Merrill, L. L., and Emens-Hesslink, K.

Abstract

There are more than 55,000 women on active duty in the U.S. Navy. Previous research has shown that women utilize health care services at higher rates than men, and that obstetric and gynecologic (OB/GYN) health care are among the most frequent reasons for such visits. The present study assessed U.S. Navy women's perceptions of the quality of OB/GYN medical care provided by the Navy. Health care satisfaction surveys were mailed to 42 randomly selected shore units and were returned by 560 enlisted women. U.S. Navy women who participated in this study were satisfied with both OB and GYN medical care. More than 80% reported that the Navy's OB/GYN health care program met most or almost all of their needs. Female personnel who were older, who had more years of military service, who were of higher rank, and who were married reported the highest levels of satisfaction with OB/GYN medical care. The higher levels of OB/GYN medical care satisfaction these Navy women reported may be due to greater organizational commitment among more experienced personnel.

Published
1997

260. Childhood Abuse and Sexual Revictimization in a Female Navy Recruit Sample.

Author

NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA, Merrill, L. L., Newerll, C. E., Gold, S. R., Milner, J. S., NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA, Merrill, L. L., Newerll, C. E., Gold, S. R., and Milner, J. S.

Abstract

A sample of female Navy recruits were surveyed for preliminary histories of child abuse and adult rape. The results show that 55.4% of women who reported childhood sexual abuse reported subsequent rape, whereas 20.2% of the women who reported no childhood abuse reported rape. Women with a childhood history of sexual abuse were 4.70 times more likely to have been raped. The highest rape rates were reported by women with a combined childhood history of physical and sexual abuse. Ethnic differences in reports of childhood abuse and rates of revictimization were found. A regression analysis of the relative contributions of childhood sexual abuse, number of sex partners, and alcohol problems indicated childhood sexual abuse was the best predictor of adult rape.

Published
1997

261. Trifluoroacetic Acid-Mediated Cleavage of a Triethylsilyl Protecting Group: Application in the Final Step of the Semisynthetic Route to Paclitaxel (Taxol)

Author

Singh, Ambarish K., primary, Weaver, Raymond E., additional, Powers, Gerald L., additional, Rosso, Victor W., additional, Wei, Chenkou, additional, Lust, David A., additional, Kotnis, Atul S., additional, Comezoglu, F. Taha, additional, Liu, Mark, additional, Bembenek, Kenneth S., additional, Phan, Bich D., additional, Vanyo, Dale J., additional, Davies, Merrill L., additional, Mathew, Rachel, additional, Palaniswamy, Venkatapuram A., additional, Li, Wen-Sen, additional, Gadamsetti, Kumar, additional, Spagnuolo, Ciro J., additional, and Winter, William J., additional

Published
2002
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266. User's Guide for the Navy Computer-Assisted Medical Diagnosis (NCAMD) System. Version 2.0.

Author

NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA, Ly, Hoa L., Merrill, L. L., Pearsall, D. M., NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA, Ly, Hoa L., Merrill, L. L., and Pearsall, D. M.

Abstract

The Navy Computer-Assisted Medical Diagnosis (NCAMD) system is designed to assist Independent Duty Corpsmen (IDCs) in rendering a medical diagnosis. The NCAMD system was written using Microsoft FoxPro, Version 2.0, database management system. For each encounter the signs, symptoms, and laboratory information collected can be gathered on data entry forms created for NCAMD or entered directly (real time) into the system. A Chronological Record of Medical Care (SF600) can be generated automatically to document the encounter. The NCAMD system User's Guide was written to familiarize the IDCs with the NCAMD software. The keyboard and mouse commands necessary to run the various options are explained in conjunction with the associated screens.

Published
1995

277. Flags of Our Fathers

Author

Merrill L. Bartlett, James Bradley, and Ron Powers

Subjects
History
Published
2001

278. Aneurysmal Bone Cyst of the First Cervical Vertebrae in a Child Treated With Percutaneous Intralesional Injection of Calcitonin and Methylprednisolone

Author

Merrill L. Gladden, Luke M. Vaughan, William L. Hennrikus, and Bruce L. Gillingham

Subjects
Calcitonin, medicine.medical_specialty, Percutaneous, medicine.drug_class, Injections, Intralesional, Methylprednisolone, medicine, Humans, Orthopedics and Sports Medicine, Cervical Atlas, Bone cyst, business.industry, Aneurysmal bone cyst, medicine.disease, Magnetic Resonance Imaging, Vertebra, Surgery, Bone Cysts, Aneurysmal, medicine.anatomical_structure, Child, Preschool, Corticosteroid, Female, Neurology (clinical), Tomography, X-Ray Computed, business, medicine.drug, Cervical vertebrae
Abstract

First published report of a child with an aneurysmal bone cyst (ABC) of the first cervical vertebrae treated successfully with intralesional injection of calcitonin and methylprednisolone.To describe a safe and effective nonsurgical treatment method for an ABC of the first cervical vertebrae.Aneurysmal bone cysts of the spine comprise from 3% to 20% of all such lesions. Upper cervical spine involvement is rare and these lesions are difficult to treat. Standard treatment with curettage and bone grafting or other alternatives such as radiation therapy or embolization may not be possible in this location. Percutaneous injection with a variety of agents has also been described. Methylprednisolone and calcitonin were selected in this case in an effort to combine the proposed angiostatic and fibroblastic inhibitory effects of steroid with the proposed osteoclastic inhibitory and promotion of new bony trabeculae formation effects of calcitonin.This case was described, and pertinent literature reviewed.Sclerosis and shrinkage of the lesion with concomitant symptom resolution occurred after two injections with calcitonin and methylprednisolone via computed tomography (CT) guidance. No complications occurred. The lesion remained quiescent at a 2-year 7-month follow-up.Percutaneous intralesional injection of an ABC of the first cervical vertebrae with calcitonin and methylprednisolone in a child via CT guidance was a safe and effective treatment. This is a promising treatment for surgically inaccessible aneurysmal bone cysts.

Published
2000

279. Electron drift velocities in xenon and xenon‐nitrogen gas mixtures

Author

E. L. Patrick, Merrill L. Andrews, and A. Garscadden

Subjects
Electron mobility, Drift velocity, Physics and Astronomy (miscellaneous), Physics::Instrumentation and Detectors, Chemistry, Analytical chemistry, chemistry.chemical_element, Electron, Plasma, Nitrogen, Electron drift, Xenon, Nitrogen gas, Atomic physics
Abstract

The drift velocity of an electron swarm in pure xenon gas (99.995% pure) and xenon gas mixtures, containing 0.1%, 1%, and 10% nitrogen additive, was measured in a pulsed‐Townsend drift tube in order to observe the effects of the additives on electron mobility, and to demonstrate negative differential conductivity. The digitized signal was analyzed by a microcomputer to produce swarm drift time measurements. The amount of nitrogen necessary to perturb the electron drift velocity in pure xenon is implied from these measurements.

Published
1991

281. Process Development of 5-Fluoro-3-[3-[4-(5-methoxy-4-pyrimidinyl)-1- piperazinyl]propyl]-1H-indole Dihydrochloride

Author

Anderson, Neal G., primary, Ary, Thomas D., additional, Berg, James L., additional, Bernot, Peter J., additional, Chan, Yeung Y., additional, Chen, Chien-Kuang, additional, Davies, Merrill L., additional, DiMarco, John D., additional, Dennis, Ronald D., additional, Deshpande, Rajan P., additional, Do, Hoang D., additional, Droghini, Roberto, additional, Early, William A., additional, Gougoutas, Jack Z., additional, Grosso, John A., additional, Harris, John C., additional, Haas, Oscar W., additional, Jass, Paul A., additional, Kim, Daniel H., additional, Kodersha, Gus A., additional, Kotnis, Atul S., additional, LaJeunesse, Jean, additional, Lust, David A., additional, Madding, Gary D., additional, Modi, Sandeep P., additional, Moniot, Jerome L., additional, Nguyen, Andrew, additional, Palaniswamy, Venkatapuram, additional, Phillipson, Douglas W., additional, Simpson, James H., additional, Thoraval, Dominique, additional, Thurston, David A., additional, Tse, Kai, additional, Polomski, Robert E., additional, Wedding, Donald L., additional, and Winter, William J., additional

Published
1997
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288. Phase Line Green: The Battle for Hue, 1968

Author

Nicholas Warr, Gary D. Solis, and Merrill L. Bartlett

Subjects
History, Battle, Vietnam War, media_common.quotation_subject, Law, Ancient history, media_common, Hue
Published
1998

293. A Magnificent Fight: The Battle for Wake Island

Author

Merrill L. Bartlett and Robert J. Cressman

Subjects
History, geography, Battle, geography.geographical_feature_category, Wake Island, media_common.quotation_subject, Nearly Daily, Atoll, Art, Archaeology, media_common
Abstract

Recounts how the Wake Island garrison survived nearly daily bombings and repulsed the first Japanese attempt to take the atoll.

Published
1996

294. Effect of systemic blockade of α1-noradrenergic receptors on sex behavior and vaginal–cervical stimulation-induced Fos in female rats

Author

Kirkpatrick, M.E. and Merrill, L.

Subjects
*ANIMAL sexual behavior, *ADRENERGIC receptors, *SENSORY stimulation, *LABORATORY mice, *PRAZOSIN, *NORADRENERGIC mechanisms, *DRUG efficacy
Abstract

Abstract: It is hypothesized that systemic α1-noradrenergic antagonists may interfere with the transmission of sensory stimulation, particularly vaginal–-cervical stimulation (VCS), which is crucial for reproductive functioning. To determine if α1-noradrenergic transmission receptor activity is necessary for transmission of sensory information important for VCS-dependent events, we conducted an experiment using prazosin, a α1-noradrenergic receptor antagonist. First, three doses of prazosin (1.0, 0.5 or 0.1mg/kg) or the 10% ETOH in sesame oil vehicle were administered i.p. and sexual receptivity was assessed 30min later in ovariectomized, hormone-treated female rats. The 1mg/kg dose of prazosin significantly inhibited lordosis quotients and lordosis ratings. This dose of prazosin (1.0mg/kg) was then administered 30min prior to VCS or control scapular stimulation (CSS) and Fos-IR was examined in the posterodorsal medial amygdala (MeaPD), the medial preoptic area (mPOA), and the rostral ventromedial hypothalamus (rVMH). VCS significantly increased Fos-IR in all of the brain areas examined. Prazosin treatment inhibited the increase in Fos-IR in the mPOA and MeaPD but not in the rVMH. These results suggest that administration of systemic prazosin may selectively affect sensory inputs to the mPOA and MeaPD and these inputs are relevant for the control of female sexual behaviors by peripheral α1-noradrenergic activity. [ABSTRACT FROM AUTHOR]

Published
2011
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296. Book reviews.

Author

Fisher JT, Hughes RS, Masters A, Merrill L, Newell CJ, Nosek MA, Omansky B, Schurter DD, Walsh MB, and Yong A

Published
2007

298. 1 -Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (lspC) from Mycobacterium tuberculosis: towards Understanding Mycobacterial Resistance to Fosmidomycin.

Author

Dhiman, Rakesh K., Schaeffer, Merrill L., Bailey, Ann Marie, Testa, Charles A., Scherman, Hataichanok, and Crick, Dean C.

Subjects
*MYCOBACTERIUM tuberculosis, *MYCOBACTERIAL diseases, *BACTERIAL diseases, *DRUG resistance in microorganisms, *TUBERCULIN, *ANTIBIOTICS
Abstract

1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) catalyzes the first committed step in the mevalonate-independent isopentenyl diphosphate biosynthetic pathway and is a potential drug target in some pathogenic bacteria. The antibiotic fosmidomycin has been shown to inhibit IspC in a number of organisms and is active against most gram-negative bacteria but not gram positives, including Mycobacterium tuberculosis, even though the mevalonate-independent pathway is the sole isopentenyl diphosphate biosynthetic pathway in this organism. Therefore, the enzymatic properties of recombinant IspC from M. tuberculosis were characterized. Rv2870c from M. tuberculosis converts 1-deoxy-D-xylulose 5-phosphate to 2-C-methyl-D-erythritol 4-phosphate in the presence of NADPH. The enzymatic activity is dependent on the presence of Mg2+ ions and exhibits optimal activity between pH 7.5 and 7.9; the Km for 1-deoxyxylulose 5-phosphate was calculated to be 47.1 μM, and the Km for NADPH was 29.7 μM. The specificity constant of Rv2780c in the forward direction is 1.5 ⊗ 106 M-1 min-1, and the reaction is inhibited by fosmidomycin, with a 50% inhibitory concentration of 310 nM. In addition, Rv2870c complements an inactivated chromosomal copy of IspC in Salmonella enterica, and the complemented strain is sensitive to fosmidomycin. Thus, M. tuberculosis resistance to fosmidomycin is not due to intrinsic properties of Rv2870c, and the enzyme appears to be a valid drug target in this pathogen. [ABSTRACT FROM AUTHOR]

Published
2005
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