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5,376 results on '"Li, Xuemei"'

256. A KAM-Theorem for Persistence of Quasi-periodic Invariant Tori in Bifurcation Theory of Equilibrium Points

Author

Li, Xuemei and Shang, Zaijiu

Subjects
Mathematics - Dynamical Systems
Abstract

In this paper, we establish a KAM-theorem for ordinary differential equations with finitely differentiable vector fields and multiple degeneracies. The theorem can be used to deal with the persistence of quasi-periodic invariant tori in multiple Hopf and zero-multiple Hopf bifurcations, as well as their subordinate bifurcations, of equilibrium points of continuous dynamical systems., Comment: 38pages

Published
2018

260. Research Hotspots of Multidrug-resistant Organisms in China from 2000 to 2020: a Visualization Analysis

Author

Qi ZHANG, Baozhen LI, Xuemei ZHENG, Baohua PING, Xiaoyan WANG, Qian LI

Subjects
drug resistance, multiple, bacterial, data visualization, multidrug resistance bacteria, visual analysis, citespace, bibliometrics, Medicine
Abstract

Background Multidrug-resistant organisms (MDROs) may increase the risk of nosocomial infection and impose great economic burden on patients' families and society. So it is of great significance to analyze the status, especially hotspots of research on MDROs for further research. Objective To analyze the research hotspots of MDROs in China from 2000 to 2020. Methods CiteSpace and bibliometric methods were used to conduct a visualization analysis of studies related to MDROs included in CNKI database of China in recent 20 years, involving the regularity of growth, high-frequency keywords, evolution of research hotspots and so on. Results In all, 3 808 studies were included. The number of these studies published during 2000—2020 demonstrated an upward trend in general, and could be divided into five stages: low output (2000—2004) , slow growth (2005—2009) , rapid growth (2010—2015) , relatively stable growth (2016—2018) and further development (2019—2020) . A total of 221 nodes and 302 edges were found by keywords co-occurrence network analysis. And besides MDROs and multidrug resistance, the central value of other 10 of the top 20 most frequently used keywords was equal or over 0.10, including nosocomial infection, multiple drug-resistant bacterial infections, Pseudomonas aeruginosa, ICU, Escherichia coli, drug resistance, antibiotics, Klebsiella pneumoniae, drug sensitivity test, and intensive care unit. The keywords were clustered into 15 clusters by cluster analysis, mainly included the following four themes: multiple resistant strains, multidrug-resistant bacteria infection and prognosis, diseases leading to multiple drug-resistant bacteria infections, generation mechanism and prevention and control of MDROs. The highly cited burst-related words mainly were drug resistant strains, drug resistance, antibacterial agents, and integron from 2000 to 2013, but there were no burst-related words after 2013. Conclusion The number of studies about MDROs in China demonstrated an overall upward trend from 2000 to 2020, with nosocomial infection, antibacterial agents, key drug-resistant strains and integron as the research hotspots, but few of them were about surveillance of drug resistance.

Published
2022
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272. The Enhancement Effects of Forsythoside E on Serum Albumin Fluorescence Under Simulated Physiological Conditions

Author

Dang, Li, Li, Xuemei, Guo, Sifan, and Du, Huizhi

Subjects
Fluorescence -- Analysis, Albumin -- Analysis, Chemistry, Engineering and manufacturing industries, Physics, Science and technology
Abstract

This study examines the fluorescence enhancement effects of forsythoside E, one of metabolites of Forsythia suspensa, on human serum albumin (HSA) and bovine serum albumin (BSA) under simulated physiological conditions. [...]

Published
2022

296. Quasi-periodic solutions for differential equations with an elliptic-type degenerate equilibrium point under small perturbations

Author

Li, Xuemei and Shang, Zaijiu

Subjects
Mathematics - Dynamical Systems
Abstract

This work focuses on the existence of quasi-periodic solutions for ordinary and delay differential equations (ODEs and DDEs for short) with an elliptic-type degenerate equilibrium point under quasi-periodic perturbations. We prove that under appropriate hypotheses there exist quasi-periodic solutions for perturbed ODEs and DDEs near the equilibrium point for most parameter values, then apply these results to the delayed van der Pol's oscillator with zero-Hopf singularity., Comment: 32pages

Published
2017

299. Salvianolic acid B improves the microcirculation in a mouse model of sepsis through a mechanism involving the platelet receptor CD226.

Author

Li, Xuemei, Liu, Shanshou, Xie, Jiangang, Liu, Lin, Duan, Chujun, Yang, Lu, Wang, Yuling, Wu, Yilin, Shan, Niqi, Zhang, Yun, Zhang, Yuan, and Zhuang, Ran

Subjects
*PLATELET count, *TREATMENT effectiveness, *CELL aggregation, *TISSUE adhesions, *BLOOD flow, *BLOOD platelet aggregation
Abstract

Background and Purpose Experimental Approach Key Results Conclusion and Implications Salvianolic acid B (SalB) demonstrates diverse clinical applications, particularly in cardiovascular and cerebral protection. This study primarily investigated the effects of SalB on sepsis.The model of sepsis via caecal ligation puncture (CLP) was established in male C57BL/6 mice. Therapeutic effects of SalB on hepatic and pulmonary injury, inflammatory responses and microcirculatory disturbances in sepsis were evaluated. Platelet aggregation and adhesion were measured via flow cytometry and an adhesion test. After overexpression of platelet‐related activating molecules by 293T cells, the efficient binding of SalB and platelet CD226 molecules was further evaluated. Finally, neutralizing antibody experiments were used to assess the mechanism of SalB in alleviating the progression of sepsis.SalB mitigated hepatic and pulmonary impairments, reduced inflammatory cytokine levels and enhanced mesenteric microvascular blood flow in septic mice. SalB enhanced CLP‐induced reduction of platelet count and platelet pressure cumulative volume. SalB reduced platelet adhesion to endothelial cells and platelet aggregation to leukocytes. A high binding efficiency was observed between SalB and the platelet adhesion molecule CD226. Ex vivo, interactions between SalB and platelets from CD226‐knockout mice were markedly decreased. In vivo administration of CD226 neutralizing antibodies significantly delayed disease progression and enhanced mesenteric microcirculation in septic mice.In our murine model of sepsis, treatment with SalB improved the microcirculatory disturbance and hindered the progression of sepsis by inhibiting platelet CD226 function. Our results suggest SalB is a promising therapeutic approach to the treatment of sepsis. [ABSTRACT FROM AUTHOR]

Published
2024
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