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251. Gabapentin in Horses: Validation of an Analytical Method for Gabapentin Quantitation

Author: Thomas Tobin, K. J. Ely, Andreas F. Lehner, H. ElkHoly, K. Thompson, J. Stewart, Levent Dirikolu, C. N. Jones, A. L. Connerly, and A. Dafalla
Subjects: Cyclohexanecarboxylic Acids, Gabapentin, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Toxicology, Gas Chromatography-Mass Spectrometry, Analytical Chemistry, chemistry.chemical_compound, Pharmacokinetics, medicine, Animals, Environmental Chemistry, Horses, Solid phase extraction, Amines, Derivatization, gamma-Aminobutyric Acid, Doping in Sports, Detection limit, Analgesics, Chemical Health and Safety, Chromatography, Chemistry, Solid Phase Extraction, Standard curve, Anticonvulsant, Anti-Anxiety Agents, Anticonvulsants, Female, Quantitative analysis (chemistry), medicine.drug
Abstract: Gabapentin [1-(aminomethyl)cyclohexaneacetic acid, Neurontin], is a new anticonvulsant used as adjunctive therapy in the treatment of partial seizures in humans not controlled with standard antiseizure drugs, and it has also been used in veterinary medicine. In performance horses, gabapentin is listed as a class 3 performance-enhancing substance by the Association of Racing Commissioners International, and thus is considered to have the potential to influence the outcome of races. Therefore, we developed and validated a sensitive gas chromatographic-mass spectrometric (GC-MS) method for gabapentin detection. Gamma-aminobutyric acid-d(2) (GABA-d(2)) was used as an internal standard during solid-phase extraction; lacking the cyclohexyl ring of gabapentin, GABA-d(2) formed a lactam structure to only a minor extent. Gabapentin, on the other hand, readily formed a lactam on thermal exposure during trimethylsilyl-derivatization and/or GC analysis; electrospray-ionization MS was employed to verify that the original compound was present as the expected 171 m.w. compound. Extraction efficiency for the assay was about 60%, and a curvilinear standard curve ranging from 50 ng/mL to 3000 ng/mL provided excellent within-run and between-run coefficients of variation and accuracies over a range of low, medium, and high values. The limit of detection, defined as the concentration calculated from the mean response at zero concentration plus two times the standard deviation, was calculated at 7.6 ng/mL; the limit of quantitation, defined as the concentration calculated from the mean of the zero responses plus five times the standard deviation, was calculated at 17 ng/mL. This method will enable accurate quantification of gabapentin in equine biological fluids for use in both pharmacokinetic and forensic studies.
Published: 2007

252. Zγ production and limits on anomalous ZZγ and Zγγ couplings in pp¯ collisions at s=1.96 TeV

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, E. Aguilo, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, L.S. Ancu, T. Andeen, S. Anderson, B. Andrieu, M.S. Anzelc, Y. Arnoud, M. Arov, M. Arthaud, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C. Ay, F. Badaud, A. Baden, L. Bagby, B. Baldin, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, A.-F. Barfuss, P. Bargassa, P. Baringer, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, S. Beale, A. Bean, M. Begalli, M. Begel, C. Belanger-Champagne, L. Bellantoni, A. Bellavance, J.A. Benitez, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, C. Biscarat, G. Blazey, F. Blekman, S. Blessing, D. Bloch, K. Bloom, A. Boehnlein, D. Boline, T.A. Bolton, G. Borissov, K. Bos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, S. Burdin, S. Burke, T.H. Burnett, C.P. Buszello, J.M. Butler, P. Calfayan, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K. Chan, K.M. Chan, A. Chandra, F. Charles, E. Cheu, F. Chevallier, D.K. Cho, S. Choi, B. Choudhary, L. Christofek, T. Christoudias, S. Cihangir, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, M. Corcoran, F. Couderc, M.-C. Cousinou, S. Crépé-Renaudin, D. Cutts, M. Ćwiok, H. da Motta, A. Das, G. Davies, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, A. Dominguez, H. Dong, L.V. Dudko, L. Duflot, S.R. Dugad, D. Duggan, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, J. Ellison, V.D. Elvira, Y. Enari, S. Eno, P. Ermolov, H. Evans, A. Evdokimov, V.N. Evdokimov, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, M. Ford, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, V. Gavrilov, P. Gay, W. Geist, D. Gelé, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, N. Gollub, B. Gómez, A. Goussiou, P.D. Grannis, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, A. Grohsjean, S. Grünendahl, M.W. Grünewald, F. Guo, J. Guo, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, P. Haefner, S. Hagopian, J. Haley, I. Hall, R.E. Hall, L. Han, K. Hanagaki, P. Hansson, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, K. Herner, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, H. Hoeth, M. Hohlfeld, S.J. Hong, R. Hooper, S. Hossain, P. Houben, Y. Hu, Z. Hubacek, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, K. Jakobs, C. Jarvis, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, S. Kappler, D. Karmanov, J. Kasper, P. Kasper, I. Katsanos, D. Kau, R. Kaur, V. Kaushik, R. Kehoe, S. Kermiche, N. Khalatyan, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, M.H. Kirby, M. Kirsch, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, B. Kothari, A.V. Kozelov, D. Krop, A. Kryemadhi, T. Kuhl, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, D. Lam, S. Lammers, G. Landsberg, J. Lazoflores, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, J. Lellouch, V. Lesne, J. Leveque, P. Lewis, J. Li, L. Li, Q.Z. Li, S.M. Lietti, J.G.R. Lima, D. Lincoln, J. Linnemann, V.V. Lipaev, R. Lipton, Y. Liu, Z. Liu, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, A.L. Lyon, A.K.A. Maciel, D. Mackin, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, B. Martin, R. McCarthy, A. Melnitchouk, A. Mendes, L. Mendoza, P.G. Mercadante, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, T. Millet, J. Mitrevski, J. Molina, R.K. Mommsen, N.K. Mondal, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, M. Mulhearn, O. Mundal, L. Mundim, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, P. Neustroev, H. Nilsen, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, V. O'Dell, D.C. O'Neil, G. Obrant, C. Ochando, D. Onoprienko, N. Oshima, J. Osta, R. Otec, G.J. Otero y Garzón, M. Owen, P. Padley, M. Pangilinan, N. Parashar, S.-J. Park, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, K. Peters, Y. Peters, P. Pétroff, M. Petteni, R. Piegaia, J. Piper, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, A.V. Popov, C. Potter, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, A. Rakitine, M.S. Rangel, K.J. Rani, K. Ranjan, P.N. Ratoff, P. Renkel, S. Reucroft, P. Rich, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, G. Safronov, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, T. Schliephake, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, J. Sekaric, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, R.K. Shivpuri, D. Shpakov, V. Siccardi, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, D. Smirnov, R.P. Smith, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, S. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, P. Svoisky, A. Sznajder, M. Talby, P. Tamburello, A. Tanasijczuk, W. Taylor, P. Telford, J. Temple, B. Tiller, F. Tissandier, M. Titov, V.V. Tokmenin, M. Tomoto, T. Toole, I. Torchiani, T. Trefzger, D. Tsybychev, B. Tuchming, C. Tully, P.M. Tuts, R. Unalan, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, B. van Eijk, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, P. Vint, E. Von Toerne, M. Voutilainen, M. Vreeswijk, R. Wagner, H.D. Wahl, L. Wang, M.H.L. S Wang, J. Warchol, G. Watts, M. Wayne, G. Weber, M. Weber, H. Weerts, A. Wenger, N. Wermes, M. Wetstein, A. White, D. Wicke, G.W. Wilson, S.J. Wimpenny, M. Wobisch, D.R. Wood, T.R. Wyatt, Y. Xie, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, K. Yip, H.D. Yoo, S.W. Youn, C. Yu, J. Yu, A. Yurkewicz, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, L. Zivkovic, V. Zutshi, and E.G. Zverev
Subjects: Physics, Nuclear and High Energy Physics, Gauge boson, Particle physics, Muon, Large Hadron Collider, 010308 nuclear & particles physics, Tevatron, 01 natural sciences, 7. Clean energy, law.invention, Standard Model, Nuclear physics, law, 0103 physical sciences, High Energy Physics::Experiment, Fermilab, 010306 general physics, Collider, Lepton
Abstract: We present a study of eey and mu mu gamma events using 1109 (1009) pb-(1) of data in the electron (muon) channel, respectively. These data were collected with the DO detector at the Fermilab Tevatron pp collider at Is = 1.96 TeV. Having observed 453 (515) candidates in the eey (jtAy) final state, we measure the Z gamma production cross section for a photon with transverse energy ET > 7 GeV, separation between the photon and leptons Delta Rey > 0.7, and invariant mass of the di-lepton pair Mee > 30 GeV/(2)(c), to be 4.96 0.30(stat. + syst.) zE 0.30(lumi.) pb, in agreement with the Standard Model prediction of 4.74 0.22 pb. This is the most precise Zy cross section measurement at a hadron collider. We set limits on anomalous trilinear Zyy and ZZy gauge boson couplings of -0.085 < h(30)(y) < 0.084, -0.0053 < h(40)(y) < 0.0054 and -0.083 < h(30)(Z) < 0.082, 30 40 30 -0.0053 < h(40)(Z) < 0.0054 at the 95% C.L. for the form-factor scale A = 1.2 TeV. 40 .
Published: 2007

253. Rapid effects of acute anoxia on spindle kinetochore interactions activate the mitotic spindle checkpoint

Author: Sebastian Heeger, Rahul Pandey, and Christian F. Lehner
Subjects: Centrosome, Embryo, Nonmammalian, Cell cycle checkpoint, Kinetochore, Molecular Motor Proteins, Spindle midzone, Spindle Apparatus, Cell Biology, Biology, Mitotic spindle checkpoint, Spindle pole body, Cell biology, Spindle apparatus, Electron Transport Complex IV, Oxygen, Spindle checkpoint, Drosophila melanogaster, Animals, Drosophila Proteins, Anaerobiosis, Enzyme Inhibitors, Anaphase-promoting complex, Kinetochores
Abstract: The dramatic chromosome instability in certain tumors might reflect a synergy of spindle checkpoint defects with hypoxic conditions. In Caenorhabditis elegans and Drosophila melanogaster, spindle checkpoint activation has been implicated in the response to acute anoxia. The activation mechanism is unknown. Our analyses in D. melanogaster demonstrate that oxygen deprivation affects microtubule organization within minutes. The rapid effects of anoxia are identical in wild-type and spindle checkpoint-deficient Mps1 mutant embryos. Therefore, the anoxia effects on the mitotic spindle are not a secondary consequence of spindle checkpoint activation. Some motor, centrosome and kinetochore proteins (dynein, Kin-8, Cnn, TACC, Cenp-C, Nuf2) are rapidly relocalized after oxygen deprivation. Kinetochores congress inefficiently into the metaphase plate and do not experience normal pulling forces. Spindle checkpoint proteins accumulate mainly within the spindle midzone and inhibit anaphase onset. In checkpoint-deficient embryos, mitosis is still completed after oxygen deprivation, although accompanied by massive chromosome missegregation. Inhibitors of oxidative phosphorylation mimic anoxia effects. We conclude that oxygen deprivation impairs the chromosome segregation machinery more rapidly than spindle checkpoint function. Although involving adenosine triphosphate (ATP)-consuming kinases, the spindle checkpoint can therefore be activated by spindle damage in response to acute anoxia and protect against aneuploidies.
Published: 2007

254. Search for single production of scalar leptoquarks in pp¯ collisions decaying into muons and quarks with the D0 detector

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, E. Aguilo, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, L.S. Ancu, T. Andeen, S. Anderson, B. Andrieu, M.S. Anzelc, Y. Arnoud, M. Arov, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C. Ay, F. Badaud, A. Baden, L. Bagby, B. Baldin, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, P. Bargassa, P. Baringer, C. Barnes, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, S. Beale, A. Bean, M. Begalli, M. Begel, C. Belanger-Champagne, L. Bellantoni, A. Bellavance, J.A. Benitez, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, M. Binder, C. Biscarat, I. Blackler, G. Blazey, F. Blekman, S. Blessing, D. Bloch, K. Bloom, A. Boehnlein, D. Boline, T.A. Bolton, G. Borissov, K. Bos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, S. Burdin, S. Burke, T.H. Burnett, E. Busato, C.P. Buszello, J.M. Butler, P. Calfayan, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K.M. Chan, A. Chandra, F. Charles, E. Cheu, F. Chevallier, D.K. Cho, S. Choi, B. Choudhary, T. Christiansen, L. Christofek, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, M. Corcoran, F. Couderc, M.-C. Cousinou, B. Cox, S. Crépé-Renaudin, D. Cutts, M. Ćwiok, H. da Motta, A. Das, M. Das, B. Davies, G. Davies, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, M. Doidge, A. Dominguez, H. Dong, L.V. Dudko, L. Duflot, S.R. Dugad, D. Duggan, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, J. Ellison, V.D. Elvira, Y. Enari, S. Eno, P. Ermolov, H. Evans, A. Evdokimov, V.N. Evdokimov, L. Feligioni, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, M. Ford, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, V. Gavrilov, A. Gay, P. Gay, W. Geist, D. Gelé, R. Gelhaus, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, N. Gollub, B. Gómez, A. Goussiou, P.D. Grannis, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, A. Grohsjean, S. Grünendahl, M.W. Grünewald, F. Guo, J. Guo, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, P. Haefner, S. Hagopian, J. Haley, I. Hall, R.E. Hall, L. Han, K. Hanagaki, P. Hansson, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, K. Herner, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, H. Hoeth, M. Hohlfeld, S.J. Hong, R. Hooper, P. Houben, Y. Hu, Z. Hubacek, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, K. Jakobs, C. Jarvis, A. Jenkins, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, S. Kappler, D. Karmanov, J. Kasper, P. Kasper, I. Katsanos, D. Kau, R. Kaur, R. Kehoe, S. Kermiche, N. Khalatyan, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, M.H. Kirby, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, J. Kotcher, B. Kothari, A. Koubarovsky, A.V. Kozelov, D. Krop, A. Kryemadhi, T. Kuhl, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, D. Lam, S. Lammers, G. Landsberg, J. Lazoflores, A.-C. Le Bihan, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, V. Lesne, J. Leveque, P. Lewis, J. Li, L. Li, Q.Z. Li, S.M. Lietti, J.G.R. Lima, D. Lincoln, J. Linnemann, V.V. Lipaev, R. Lipton, Z. Liu, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, M. Lynker, A.L. Lyon, A.K.A. Maciel, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, R. McCarthy, A. Melnitchouk, A. Mendes, L. Mendoza, P.G. Mercadante, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, H. Miettinen, T. Millet, J. Mitrevski, J. Molina, R.K. Mommsen, N.K. Mondal, J. Monk, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, M. Mulhearn, O. Mundal, L. Mundim, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, P. Neustroev, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, V. O'Dell, D.C. O'Neil, G. Obrant, C. Ochando, V. Oguri, N. Oliveira, D. Onoprienko, N. Oshima, J. Osta, R. Otec, G.J. Otero y Garzón, M. Owen, P. Padley, M. Pangilinan, N. Parashar, S.-J. Park, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, K. Peters, Y. Peters, P. Pétroff, M. Petteni, R. Piegaia, J. Piper, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, A.V. Popov, C. Potter, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, M.S. Rangel, K.J. Rani, K. Ranjan, P.N. Ratoff, P. Renkel, S. Reucroft, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, J. Sekaric, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, R.K. Shivpuri, D. Shpakov, V. Siccardi, R.A. Sidwell, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, R.P. Smith, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, X. Song, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, S. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, P. Svoisky, A. Sznajder, M. Talby, P. Tamburello, W. Taylor, P. Telford, J. Temple, B. Tiller, M. Titov, V.V. Tokmenin, M. Tomoto, T. Toole, I. Torchiani, T. Trefzger, S. Trincaz-Duvoid, D. Tsybychev, B. Tuchming, C. Tully, P.M. Tuts, R. Unalan, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, B. van Eijk, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, P. Vint, J.-R. Vlimant, E. Von Toerne, M. Voutilainen, M. Vreeswijk, H.D. Wahl, L. Wang, M.H.L.S. Wang, J. Warchol, G. Watts, M. Wayne, G. Weber, M. Weber, H. Weerts, N. Wermes, M. Wetstein, A. White, D. Wicke, G.W. Wilson, S.J. Wimpenny, M. Wobisch, J. Womersley, D.R. Wood, T.R. Wyatt, Y. Xie, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, K. Yip, H.D. Yoo, S.W. Youn, C. Yu, J. Yu, A. Yurkewicz, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, V. Zutshi, and E.G. Zverev
Subjects: Physics, Quark, Nuclear and High Energy Physics, Particle physics, Muon, 010308 nuclear & particles physics, Branching fraction, High Energy Physics::Phenomenology, Scalar (mathematics), Lambda, 01 natural sciences, Upper and lower bounds, Nuclear physics, Pair production, 0103 physical sciences, High Energy Physics::Experiment, Leptoquark, 010306 general physics
Abstract: We report on a search for second generation leptoquarks LQ_2 which decay into a muon plus quark in p\bar{p} collisions at a center-of-mass energy of sqrt{s} = 1.96 TeV in the D0 detector using an integrated luminosity of about 300 pb-1. No evidence for a leptoquark signal is observed and an upper bound on the product of the cross section for single leptoquark production times branching fraction beta into a quark and a muon was determined for second generation scalar leptoquarks as a function of the leptoquark mass. This result has been combined with a previously published D0 search for leptoquark pair production to obtain leptoquark mass limits as a function of the leptoquark-muon-quark coupling, lambda. Assuming lambda=1, lower limits on the mass of a second generation scalar leptoquark are m{LQ_2}>274 GeV and m{LQ_2}>226 GeV for beta=1 and beta=1/2, respectively.
Published: 2007

255. Search for the pair production of scalar top quarks in the acoplanar charm jet final state in collisions at

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, E. Aguilo, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, L.S. Ancu, T. Andeen, S. Anderson, B. Andrieu, M.S. Anzelc, Y. Arnoud, M. Arov, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C. Ay, F. Badaud, A. Baden, L. Bagby, B. Baldin, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, P. Bargassa, P. Baringer, C. Barnes, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, S. Beale, A. Bean, M. Begalli, M. Begel, C. Belanger-Champagne, L. Bellantoni, A. Bellavance, J.A. Benitez, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, M. Binder, C. Biscarat, I. Blackler, G. Blazey, F. Blekman, S. Blessing, D. Bloch, K. Bloom, U. Blumenschein, A. Boehnlein, T.A. Bolton, G. Borissov, K. Bos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, S. Burdin, S. Burke, T.H. Burnett, E. Busato, C.P. Buszello, J.M. Butler, P. Calfayan, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K.M. Chan, A. Chandra, F. Charles, E. Cheu, F. Chevallier, D.K. Cho, S. Choi, B. Choudhary, L. Christofek, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, D. Coppage, M. Corcoran, F. Couderc, M.-C. Cousinou, B. Cox, S. Crépé-Renaudin, D. Cutts, M. Ćwiok, H. da Motta, A. Das, M. Das, B. Davies, G. Davies, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, M. Doidge, A. Dominguez, H. Dong, L.V. Dudko, L. Duflot, S.R. Dugad, D. Duggan, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, J. Ellison, J. Elmsheuser, V.D. Elvira, Y. Enari, S. Eno, P. Ermolov, H. Evans, A. Evdokimov, V.N. Evdokimov, L. Feligioni, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, I. Fleck, M. Ford, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, J. Gardner, V. Gavrilov, A. Gay, P. Gay, W. Geist, D. Gelé, R. Gelhaus, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, N. Gollub, B. Gómez, A. Goussiou, P.D. Grannis, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, A. Grohsjean, S. Grünendahl, M.W. Grünewald, F. Guo, J. Guo, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, P. Haefner, S. Hagopian, J. Haley, I. Hall, R.E. Hall, L. Han, K. Hanagaki, P. Hansson, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, K. Herner, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, H. Hoeth, M. Hohlfeld, S.J. Hong, R. Hooper, P. Houben, Y. Hu, Z. Hubacek, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, K. Jakobs, C. Jarvis, A. Jenkins, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, S. Kappler, D. Karmanov, J. Kasper, P. Kasper, I. Katsanos, D. Kau, R. Kaur, R. Kehoe, S. Kermiche, N. Khalatyan, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, M.H. Kirby, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, J. Kotcher, B. Kothari, A. Koubarovsky, A.V. Kozelov, D. Krop, A. Kryemadhi, T. Kuhl, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, D. Lam, S. Lammers, G. Landsberg, J. Lazoflores, A.-C. Le Bihan, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, V. Lesne, J. Leveque, P. Lewis, J. Li, L. Li, Q.Z. Li, J.G.R. Lima, D. Lincoln, J. Linnemann, V.V. Lipaev, R. Lipton, Z. Liu, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, M. Lynker, A.L. Lyon, A.K.A. Maciel, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, A.-M. Magnan, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, M. Martens, R. McCarthy, D. Meder, A. Melnitchouk, A. Mendes, L. Mendoza, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, H. Miettinen, T. Millet, J. Mitrevski, J. Molina, R.K. Mommsen, N.K. Mondal, J. Monk, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, M. Mulhearn, O. Mundal, L. Mundim, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, P. Neustroev, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, V. O'Dell, D.C. O'Neil, G. Obrant, C. Ochando, V. Oguri, N. Oliveira, D. Onoprienko, N. Oshima, J. Osta, R. Otec, G.J. Otero y Garzón, M. Owen, P. Padley, N. Parashar, S.-J. Park, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, K. Peters, P. Pétroff, M. Petteni, R. Piegaia, J. Piper, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, A.V. Popov, C. Potter, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, M.S. Rangel, K.J. Rani, K. Ranjan, P.N. Ratoff, P. Renkel, S. Reucroft, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, V.I. Rud, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, J. Sekaric, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, R.K. Shivpuri, D. Shpakov, V. Siccardi, R.A. Sidwell, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, R.P. Smith, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, X. Song, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, S. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, P. Svoisky, A. Sznajder, M. Talby, P. Tamburello, W. Taylor, P. Telford, J. Temple, B. Tiller, M. Titov, V.V. Tokmenin, M. Tomoto, T. Toole, I. Torchiani, T. Trefzger, S. Trincaz-Duvoid, D. Tsybychev, B. Tuchming, C. Tully, P.M. Tuts, R. Unalan, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, B. van Eijk, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, P. Vint, J.-R. Vlimant, E. Von Toerne, M. Voutilainen, M. Vreeswijk, H.D. Wahl, L. Wang, M.H.L.S. Wang, J. Warchol, G. Watts, M. Wayne, G. Weber, M. Weber, H. Weerts, N. Wermes, M. Wetstein, A. White, D. Wicke, G.W. Wilson, S.J. Wimpenny, M. Wobisch, J. Womersley, D.R. Wood, T.R. Wyatt, Y. Xie, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, K. Yip, H.D. Yoo, S.W. Youn, C. Yu, J. Yu, A. Yurkewicz, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, V. Zutshi, and E.G. Zverev
Subjects: Quark, Physics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Tevatron, Supersymmetry, 01 natural sciences, 7. Clean energy, Lightest Supersymmetric Particle, Standard Model, law.invention, Nuclear physics, Pair production, law, 0103 physical sciences, High Energy Physics::Experiment, 010306 general physics, Collider, Energy (signal processing)
Abstract: A search for the pair production of scalar top quarks, {bar t}, has been performed in 360 pb{sup -1} of data from p{bar p} collisions at a center-of-mass energy of 1.96 TeV, collected by the D0 detector at the Fermilab Tevatron collider. The {bar t} decay mode considered is {bar t} {yields} c{bar {chi}}{sub 1}{sup 0}, where {bar {chi}}{sub 1}{sup 0} is the lightest supersymmetric particle. The topology analyzed therefore consists of a pair of acoplanar heavy-flavor jets with missing transverse energy. The data show good agreement with the standard model expectation, and a 95% C.L. exclusion domain in the (m{sub {tilde t}}, m{sub {tilde {chi}}{sub 1}{sup 0}}) plane has been determined, extending the domain excluded by previous experiments.
Published: 2007

256. A review of the ergot alkaloids found in endophyte-infected tall fescue and perennial ryegrass and their metabolism after ingestion by livestock

Author: Andreas F. Lehner, M.J.M. Delorme, Jennifer M. Duringer, and A. M. Craig
Subjects: Perennial plant, biology, Agronomy, business.industry, food and beverages, Ingestion, Livestock, Metabolism, biology.organism_classification, business, Endophyte
Abstract: Tall fescue (Festuca arundinacea) and perennial ryegrass (Lolium perenne) are perennial cool-season grasses which are infected with the endophytic fungi, Neotyphodium coenophialum and N. lolii, respectively. These endophytes have been increasingly selected for, as they confer benefits such as pest resistance and drought tolerance to the plant. However, livestock grazing endophyte-infected (E+) grasses are negatively impacted by fungal ergot and lolitrem alkaloids, which are responsible for a variety of mammalian diseases including fescue toxicosis (summer syndrome, fescue foot and fat necrosis) and ryegrass staggers. Most likely, not all of the ergot alkaloids involved in fescue toxicosis have been identified to date. During sample processing for the diagnostic analysis of the endophyte toxin ergovaline, other unidentified peaks occasionally elute that appear to coincide with clinical disease. Analysis of unidentified chromatographic peaks was performed on feed samples by LCMS/ MS to determine their chemical structures and identities. Ergotamine, ergovaline, ergocornine, ergonovine, ergocryptine, ergocrystine and lysergol appeared in various samples and matched controls. Newly identified compounds included ergosine, ergostine and ergoptine. In addition, several samples showed one or more of fourteen new ergots ranging in size from 381-611 mw, with key mass spectral characteristics of ergot alkaloidsspecifically, m/z 223 and 208 corresponding to the ergoline ring system and its demethylated variant, respectively. Once ingested, ergot alkaloids are thought to be metabolised in the rumen and/ or liver of livestock species. Ruminal metabolism of ergovaline was studied in sheep offered Neotyphodium coenophialuminfected tall fescue straw at two ergovaline levels (
Published: 2007

257. Search for a Higgs boson produced in association with a Z boson

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, E. Aguilo, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, L.S. Ancu, T. Andeen, S. Anderson, B. Andrieu, M.S. Anzelc, Y. Arnoud, M. Arov, M. Arthaud, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C. Ay, F. Badaud, A. Baden, L. Bagby, B. Baldin, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, A.-F. Barfuss, P. Bargassa, P. Baringer, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, S. Beale, A. Bean, M. Begalli, M. Begel, C. Belanger-Champagne, L. Bellantoni, A. Bellavance, J.A. Benitez, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, C. Biscarat, G. Blazey, F. Blekman, S. Blessing, D. Bloch, K. Bloom, A. Boehnlein, D. Boline, T.A. Bolton, G. Borissov, K. Bos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, S. Burdin, S. Burke, T.H. Burnett, C.P. Buszello, J.M. Butler, P. Calfayan, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K. Chan, K.M. Chan, A. Chandra, F. Charles, E. Cheu, F. Chevallier, D.K. Cho, S. Choi, B. Choudhary, L. Christofek, T. Christoudias, S. Cihangir, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, M. Corcoran, F. Couderc, M.-C. Cousinou, S. Crépé-Renaudin, D. Cutts, M. Ćwiok, H. da Motta, A. Das, G. Davies, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, A. Dominguez, H. Dong, L.V. Dudko, L. Duflot, S.R. Dugad, D. Duggan, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, J. Ellison, V.D. Elvira, Y. Enari, S. Eno, P. Ermolov, H. Evans, A. Evdokimov, V.N. Evdokimov, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, M. Ford, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, V. Gavrilov, P. Gay, W. Geist, D. Gelé, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, N. Gollub, B. Gómez, A. Goussiou, P.D. Grannis, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, A. Grohsjean, S. Grünendahl, M.W. Grünewald, F. Guo, J. Guo, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, P. Haefner, S. Hagopian, J. Haley, I. Hall, R.E. Hall, L. Han, K. Hanagaki, P. Hansson, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, K. Herner, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, H. Hoeth, M. Hohlfeld, S.J. Hong, R. Hooper, S. Hossain, P. Houben, Y. Hu, Z. Hubacek, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, K. Jakobs, C. Jarvis, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, S. Kappler, D. Karmanov, J. Kasper, P. Kasper, I. Katsanos, D. Kau, R. Kaur, V. Kaushik, R. Kehoe, S. Kermiche, N. Khalatyan, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, M.H. Kirby, M. Kirsch, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, B. Kothari, A.V. Kozelov, D. Krop, A. Kryemadhi, T. Kuhl, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, D. Lam, S. Lammers, G. Landsberg, J. Lazoflores, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, J. Lellouch, V. Lesne, J. Leveque, P. Lewis, J. Li, L. Li, Q.Z. Li, S.M. Lietti, J.G.R. Lima, D. Lincoln, J. Linnemann, V.V. Lipaev, R. Lipton, Y. Liu, Z. Liu, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, A.L. Lyon, A.K.A. Maciel, D. Mackin, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, B. Martin, R. McCarthy, A. Melnitchouk, A. Mendes, L. Mendoza, P.G. Mercadante, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, T. Millet, J. Mitrevski, J. Molina, R.K. Mommsen, N.K. Mondal, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, M. Mulhearn, O. Mundal, L. Mundim, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, P. Neustroev, H. Nilsen, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, V. O'Dell, D.C. O'Neil, G. Obrant, C. Ochando, D. Onoprienko, N. Oshima, J. Osta, R. Otec, G.J. Otero y Garzón, M. Owen, P. Padley, M. Pangilinan, N. Parashar, S.-J. Park, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, K. Peters, Y. Peters, P. Pétroff, M. Petteni, R. Piegaia, J. Piper, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, A.V. Popov, C. Potter, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, A. Rakitine, M.S. Rangel, K.J. Rani, K. Ranjan, P.N. Ratoff, P. Renkel, S. Reucroft, P. Rich, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, G. Safronov, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, T. Schliephake, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, J. Sekaric, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, R.K. Shivpuri, D. Shpakov, V. Siccardi, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, D. Smirnov, R.P. Smith, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, S. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, P. Svoisky, A. Sznajder, M. Talby, P. Tamburello, A. Tanasijczuk, W. Taylor, P. Telford, J. Temple, B. Tiller, F. Tissandier, M. Titov, V.V. Tokmenin, M. Tomoto, T. Toole, I. Torchiani, T. Trefzger, D. Tsybychev, B. Tuchming, C. Tully, P.M. Tuts, R. Unalan, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, B. van Eijk, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, P. Vint, E. Von Toerne, M. Voutilainen, M. Vreeswijk, R. Wagner, H.D. Wahl, L. Wang, M.H.L.S. Wang, J. Warchol, G. Watts, M. Wayne, G. Weber, M. Weber, H. Weerts, A. Wenger, N. Wermes, M. Wetstein, A. White, D. Wicke, G.W. Wilson, S.J. Wimpenny, M. Wobisch, D.R. Wood, T.R. Wyatt, Y. Xie, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, K. Yip, H.D. Yoo, S.W. Youn, C. Yu, J. Yu, A. Yurkewicz, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, L. Zivkovic, V. Zutshi, and E.G. Zverev
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Muon, Luminosity (scattering theory), 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Tevatron, 7. Clean energy, 01 natural sciences, law.invention, Standard Model, law, Experimental High Energy Physics, 0103 physical sciences, Higgs boson, High Energy Physics::Experiment, Fermilab, 010306 general physics, Collider, Boson
Abstract: We describe a search for the Standard Model Higgs boson with a mass of 105 GeV/c(2) to 145 GeV/c(2) in data corresponding to an integrated luminosity of approximately 450 pb(-1) collected with the D phi detector at the Fermilab Tevatron p (p) over bar collider at a center-of-mass energy of 1.96 TeV. The Higgs boson is required to be produced in association with a Z boson, and the Z boson is required to decay to either electrons or muons with the Higgs boson decaying to a b (b) over bar pair. The data are well described by the expected background, leading to 95% confidence level cross section upper limits sigma (p (p) over bar -> ZH) x B(H -> b (b) over bar) in the range of 3.1 pb to 4.4 pb.
Published: 2007

258. [Transplant Surgeon Meets Nephrologist: Important Nephrological Aspects Before and After Kidney or Liver Transplantation]

Author: F W R, Vondran, S, Wintterle, J H, Bräsen, H, Haller, J, Klempnauer, N, Richter, F, Lehner, and M, Schiffer
Subjects: Graft Rejection, Patient Care Team, Postoperative Complications, Humans, Interdisciplinary Communication, Primary Graft Dysfunction, Intersectoral Collaboration, Kidney Transplantation, Liver Transplantation
Abstract: In cases of chronic renal insufficiency, successful kidney transplantation is the method of choice to restore patients' health, well-being and physical fitness. The interdisciplinary collaboration of nephrologists and transplant surgeons has always been a prerequisite for the successful pre-, peri- and post-transplant care of renal transplant patients. The same holds true for liver transplant patients. Here the nephrologist is often involved in cases requiring pre- or post-transplant dialysis as well as in decision making for combined liver-kidney transplantation. This review focuses on nephrological aspects in patient care before and after kidney and liver transplantation.
Published: 2015

259. Coagulation Disorders in Subjects Undergoing Pump-Driven Veno-Venous Ecco2-R For Severe Acute Hypercapnic Respiratory Failure - a Single Center Experience

Author: Michael Joannidis, Julia Hasslacher, Georg F. Lehner, and Ulrich Harler
Subjects: medicine.medical_specialty, Acute hypercapnic respiratory failure, business.industry, medicine.medical_treatment, Endotracheal intubation, Critical Care and Intensive Care Medicine, Single Center, Hypercapnic respiratory failure, Extracorporeal, Surgery, Anesthesia, Poster Presentation, medicine, Extracorporeal membrane oxygenation, Complication, business, Coagulation Disorder
Abstract: Recent evidence suggests low-flow extracorporeal CO2 removal (ECCO2-R) systems as safe and promising adjunctive therapy to avoid endotracheal intubation and the related negative consequences in subjects with severe hypercapnic respiratory failure [1]. in high-flow extracorporeal membrane oxygenation systems heterogeneous coagulation disorders are a well-known complication. However, to date there is little evidence for the influence of pump-driven low-flow veno-venous ECCO2-R on the coagulation system.
Published: 2015

260. Effects of mild therapeutic hypothermia on acute kidney injury after cardiopulmonary resuscitation

Author: Michael Joannidis, Ulrich Harler, Julia Hasslacher, Stefan Dunzendorfer, Georg F. Lehner, and Fabian Barbieri
Subjects: medicine.medical_specialty, Creatinine, Human studies, business.industry, medicine.medical_treatment, Acute kidney injury, Renal function, Hypothermia, urologic and male genital diseases, Critical Care and Intensive Care Medicine, medicine.disease, chemistry.chemical_compound, chemistry, Poster Presentation, medicine, Cardiopulmonary resuscitation, medicine.symptom, Intensive care medicine, business
Abstract: About the effect of mild therapeutic hypothermia on renal function after cardiopulmonary resuscitation little data exists. From animal and human studies it is known that renal function might be impaired, which is not reflected by serum creatinine levels if creatinine production is reduced.
Published: 2015

261. Pharmacologic evaluation of ammonium tetrathiomolybdate after intravenous and oral administration to healthy dogs

Author: John P. Buchweitz, Marc Bailie, Christina M. Chan, Thomas H. Herdt, N. Bari Olivier, W. D. Schall, Andreas F. Lehner, and Daniel K. Langlois
Subjects: Male, Molybdenum, Cross-Over Studies, General Veterinary, Area under the curve, Administration, Oral, Biological Availability, General Medicine, Pharmacology, Ammonium tetrathiomolybdate, Crossover study, Beagle, Bioavailability, Trace Elements, chemistry.chemical_compound, Dogs, Elimination rate constant, chemistry, Pharmacokinetics, Oral administration, Animals, Administration, Intravenous, Female, Chelating Agents, Half-Life
Abstract: OBJECTIVE To evaluate pharmacokinetics of ammonium tetrathiomolybdate (TTM) after IV and oral administration to dogs and effects of TTM administration on trace mineral concentrations. ANIMALS 8 adult Beagles and Beagle crossbreds (4 sexually intact males and 4 sexually intact females). PROCEDURES Dogs received TTM (1 mg/kg) IV and orally in a randomized crossover study. Serum molybdenum and copper concentrations were measured via inductively coupled plasma mass spectrometry in samples obtained 0 to 72 hours after administration. Pharmacokinetics was determined via noncompartmental analysis. RESULTS For IV administration, mean ± SD terminal elimination rate constant, maximum concentration, area under the curve, and half-life were 0.03 ± 0.01 hours−1, 4.9 ± 0.6 μg/mL, 30.7 ± 5.4 μg/mL•h, and 27.7 ± 6.8 hours, respectively. For oral administration, mean ± SD terminal elimination rate constant, time to maximum concentration, maximum concentration, area under the curve, and half-life were 0.03 ± 0.01 hours−1, 3.0 ± 3.5 hours, 0.2 ± 0.4 μg/mL, 6.5 ± 8.0 μg/mL•h, and 26.8 ± 8.0 hours, respectively. Oral bioavailability was 21 ± 22%. Serum copper concentrations increased significantly after IV and oral administration. Emesis occurred after IV (2 dogs) and oral administration (3 dogs). CONCLUSIONS AND CLINICAL RELEVANCE Pharmacokinetics for TTM after a single IV and oral administration was determined for clinically normal dogs. Absorption of TTM after oral administration was variable. Increased serum copper concentrations suggested that TTM mobilized tissue copper. Further studies will be needed to evaluate the potential therapeutic use of TTM in copper-associated chronic hepatitis of dogs.
Published: 2015

262. A Cytochrome P450-Independent Mechanism of Acetaminophen-Induced Injury in Cultured Mouse Hepatocytes

Author: Lynda Letzig, Patricia E. Ganey, Michael A. Scott, Laura P. James, Ryan Albee, Robert A. Roth, John P. Buchweitz, Kazuhisa Miyakawa, and Andreas F. Lehner
Subjects: Male, Programmed cell death, Pharmacology, Toxicology, Mice, Cytochrome P-450 Enzyme System, Parenchyma, medicine, Animals, Cytotoxicity, Cells, Cultured, Acetaminophen, biology, Cell Death, Dose-Response Relationship, Drug, Chemistry, digestive, oral, and skin physiology, Cytochrome P450, Analgesics, Non-Narcotic, In vitro, Mice, Inbred C57BL, Dose–response relationship, Toxicity, biology.protein, Hepatocytes, Molecular Medicine, medicine.drug
Abstract: Mouse hepatic parenchymal cells (HPCs) have become the most frequently used in vitro model to study mechanisms of acetaminophen (APAP)-induced hepatotoxicity. It is universally accepted that APAP hepatocellular injury requires bioactivation by cytochromes P450 (P450s), but this remains unproven in primary mouse HPCs in vitro, especially over the wide range of concentrations that have been employed in published reports. The aim of this work was to test the hypothesis that APAP-induced hepatocellular death in vitro depends solely on P450s. We evaluated APAP cytotoxicity and APAP-protein adducts (a biomarker of metabolic bioactivation by P450) using primary mouse HPCs in the presence and absence of a broad-spectrum inhibitor of P450s, 1-aminobenzotriazole (1-ABT). 1-ABT abolished formation of APAP-protein adducts at all concentrations of APAP (0–14 mM), but eliminated cytotoxicity only at small concentrations (≦5 mM), indicating the presence of a P450-independent mechanism at larger APAP concentrations. P450-independent cell death was delayed in onset relative to toxicity observed at smaller concentrations. p-Aminophenol was detected in primary mouse HPCs exposed to large concentrations of APAP, and a deacetylase inhibitor [bis (4-nitrophenyl) phosphate (BNPP)] significantly reduced cytotoxicity. In conclusion, APAP hepatocellular injury in vitro occurs by at least two mechanisms, a P450-dependent mechanism that operates at concentrations of APAP ≦ 5 mM and a P450-independent mechanism that predominates at larger concentrations and is slower in onset. p-Aminophenol most likely contributes to the latter mechanism. These findings should be considered in interpreting results from APAP cytotoxicity studies in vitro and in selecting APAP concentrations for use in such studies.
Published: 2015

263. Determination of Organochlorine Pesticides in Wildlife Liver and Serum Using Gas Chromatography Tandem Quadrupole Mass Spectrometry

Author: Mark T. Bokhart, Andreas F. Lehner, John P. Buchweitz, and Margaret Johnson
Subjects: Detection limit, Chromatography, Blood serum, Chemistry, Extraction (chemistry), Solid phase extraction, Gas chromatography, Quechers, Mass spectrometry, Quadrupole mass analyzer
Abstract: A single laboratory validation of a quantitative capillary gas chromatography tandem quadrupole mass spectrometer (GC-MS/MS) method utilizing a Quick, Easy, Cheap, Effective, Rugged, Safe (QuEChERS) approach for the extraction of 24 organochlorine analytes in liver and blood serum is presented here. The QuEChERS approach utilizes an acetonitrile extraction, partitioning facilitated by the addition of salts and a dispersive solid phase extraction cleanup. This method simultaneously monitored 24 organochlorine pesticide residues representing four different classes, including chlordecone, cyclodienes, dichlorodiphenylethanes, and hexachlorocyclohexanes. Calculated limits of detection (LOD) varied from 0.002 to 2.4 ppb and limits of quantification (LOQ) varied from 0.01 to 7.4 ppb. This multi-residue method proved to be a sensitive approach to the measurement of persistent organic pollutants in biological matrices.
Published: 2015

264. Five-year outcomes in kidney transplant patients converted from cyclosporine to everolimus: the randomized ZEUS study

Author: K, Budde, F, Lehner, C, Sommerer, P, Reinke, W, Arns, U, Eisenberger, R P, Wüthrich, A, Mühlfeld, K, Heller, M, Porstner, J, Veit, E-M, Paulus, O, Witzke, Pierre-Alain, Clavien, University of Zurich, and Budde, K
Subjects: Graft Rejection, Male, Nephrology, 2747 Transplantation, Medizin, Pharmacology, Kidney Function Tests, Postoperative Complications, Risk Factors, Immunology and Allergy, Medicine, 2736 Pharmacology (medical), Pharmacology (medical), Cumulative incidence, 10035 Clinic for Nephrology, Kidney transplantation, education.field_of_study, Graft Survival, Middle Aged, Prognosis, Research Design, Cyclosporine, 2723 Immunology and Allergy, Female, Immunosuppressive Agents, Glomerular Filtration Rate, medicine.drug, Adult, medicine.medical_specialty, Adolescent, Population, Urology, Renal function, 610 Medicine & health, Young Adult, Internal medicine, Post-hoc analysis, Humans, Everolimus, education, Adverse effect, Aged, Sirolimus, Transplantation, business.industry, medicine.disease, Kidney Transplantation, Transplant Recipients, Kidney Failure, Chronic, business, Follow-Up Studies
Abstract: ZEUS study was an open-label, 12-month, multicenter study in which 300 de novo kidney transplant recipients were randomized to continue receiving cyclosporine (CsA) or convert to everolimus at 4.5 months posttransplant. Five-year follow-up data were available for 245/269 patients (91.1%) who completed the core 12-month study (123 everolimus, 109 CsA). At 5 years, adjusted estimated GFR was 66.2 mL/min/1.73 m(2) with everolimus versus 60.9 mL/min/1.73 m(2) with CsA; the mean difference was 5.3 mL/min/1.73 m(2) in favor of everolimus (95% CI 2.4, 8.3; p < 0.001 [intent-to-treat population]). In a post hoc analysis of patients remaining on study drug at 5 years (everolimus 77, CsA 86), mean difference was 8.2 mL/min/1.73 m(2) (95% CI 4.3, 12.1; p < 0.001) in favor of everolimus. The cumulative incidence of biopsy-proven acute rejection postrandomization was 13.6% with everolimus versus 7.5% with CsA (p = 0.095), largely accounted for by grade I rejection (16/21 patients and 7/11 patients, respectively). Postrandomization, graft loss, mortality, serious adverse events and neoplasms were similar in both arms. In conclusion, conversion of kidney transplant patients to everolimus at 4.5 months posttransplant is associated with a significant improvement in renal function that is maintained to at least 5 years. The increase in early mild acute rejection did not affect long-term graft function.
Published: 2015

265. Intravenous and intratracheal administration of trimetoquinol, a fast-acting short-lived bronchodilator in horses with ‘heaves’

Author: J. D. Harkins, F. C. Camargo, P. Detolve, Andreas F. Lehner, Frederik J. Derksen, Susan W. Eberhart, C. Berney, S. Baker, N. E. Robinson, and Thomas Tobin
Subjects: Male, Agonist, medicine.drug_class, Pharmacology, Cardiac stimulant, Drug Delivery Systems, Heart Rate, Bronchodilator, Heart rate, Intubation, Intratracheal, Animals, Medicine, Horses, Pulmonary Wedge Pressure, Cross-Over Studies, Dose-Response Relationship, Drug, business.industry, Therapeutic effect, Horse, Bronchial Diseases, General Medicine, Bronchodilator Agents, Treatment Outcome, Pharmacodynamics, Anesthesia, Injections, Intravenous, Female, Horse Diseases, Tretoquinol, Bronchoconstriction, Safety, medicine.symptom, business
Abstract: Summary Reason for performing study: Trimetoquinol (TMQ) is a potent β-adrenoceptor agonist bronchodilator used in human medicine but has not been evaluated for potential use as a therapeutic agent for horses with ‘heaves’. Objectives: To assess the pharmacodynamics of TMQ in horses with ‘heaves’ to determine potential therapeutic effects. Methods: Increasing doses of TMQ were administered to horses with ‘heaves’ by i.v. and intratracheal (i.t.) routes. Doses ranged 0.001–0.2 μg/kg bwt i.v. and 0.01–2 μg/kg bwt i.t. Cardiac and airways effects were assessed by measurement of heart rate (HR) and maximal change in pleural pressure (ΔPplmax), respectively. Side effects of sweating, agitation and muscle trembling were scored subjectively. Duration of action to i.v. (0.2 μg/kg bwt) and i.t. (2 μg/kg bwt) TMQ was evaluated over 6 h. Results: Intravenous TMQ was an exceptionally potent cardiac stimulant. Heart rate increased at 0.01 μg/kg bwt, and was still increasing after administration of highest dose, 0.2 μg/kg bwt. Airway bronchodilation, measured as a decrease in ΔPplmax, also commenced at 0.01 μg/kg bwt. By the i.t. route, TMQ was 50–100-fold less potent than by i.v. Side effects included sweating, agitation and muscle trembling. Overall, the onset of HR and bronchodilator effects was rapid, within about 3 min, but effects were over at 2 h. Conclusion: When administered i.v. and i.t., TMQ is a highly potent cardiac stimulant and a modest bronchodilator. It may not be an appropriate pharmacological agent by i.v. and i.t. routes for the alleviation of signs in horses with ‘heaves’. Further studies of TMQ by oral and aerosol routes are necessary. Potential relevance: In horses, TMQ is a fast-acting bronchodilator with a short duration of action. It could be used as a rescue agent during an episode of ‘heaves’. The i.v. and i.t. administration of TMQ is associated with side effects, similar to those reported for all other β-agonists. However, other routes, such as aerosol and oral, may prove useful and safe for the alleviation of bronchoconstriction typical of ‘heaves’.
Published: 2006

266. Search for particles decaying into a Z boson and a photon in pp¯ collisions at s=1.96 TeV

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, M. Agelou, J.-L. Agram, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, T. Andeen, S. Anderson, B. Andrieu, M.S. Anzelc, Y. Arnoud, M. Arov, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C. Ay, F. Badaud, A. Baden, L. Bagby, B. Baldin, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, P. Bargassa, P. Baringer, C. Barnes, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, A. Bean, M. Begalli, M. Begel, C. Belanger-Champagne, L. Bellantoni, A. Bellavance, J.A. Benitez, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, M. Binder, C. Biscarat, K.M. Black, I. Blackler, G. Blazey, F. Blekman, S. Blessing, D. Bloch, K. Bloom, U. Blumenschein, A. Boehnlein, O. Boeriu, T.A. Bolton, F. Borcherding, G. Borissov, K. Bos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, S. Burdin, S. Burke, T.H. Burnett, E. Busato, C.P. Buszello, J.M. Butler, P. Calfayan, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K.M. Chan, A. Chandra, D. Chapin, F. Charles, E. Cheu, F. Chevallier, D.K. Cho, S. Choi, B. Choudhary, L. Christofek, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, D. Coppage, M. Corcoran, M.-C. Cousinou, B. Cox, S. Crépé-Renaudin, D. Cutts, M. Ćwiok, H. da Motta, A. Das, M. Das, B. Davies, G. Davies, G.A. Davis, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, P. Demine, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, M. Doidge, A. Dominguez, H. Dong, L.V. Dudko, L. Duflot, S.R. Dugad, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, T. Edwards, J. Ellison, J. Elmsheuser, V.D. Elvira, S. Eno, P. Ermolov, J. Estrada, H. Evans, A. Evdokimov, V.N. Evdokimov, S.N. Fatakia, L. Feligioni, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, I. Fleck, M. Ford, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, J. Gardner, V. Gavrilov, A. Gay, P. Gay, D. Gelé, R. Gelhaus, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, N. Gollub, B. Gómez, K. Gounder, A. Goussiou, P.D. Grannis, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, S. Grünendahl, M.W. Grünewald, F. Guo, J. Guo, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, P. Haefner, S. Hagopian, J. Haley, I. Hall, R.E. Hall, L. Han, K. Hanagaki, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, H. Hoeth, M. Hohlfeld, S.J. Hong, R. Hooper, P. Houben, Y. Hu, Z. Hubacek, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, K. Jakobs, C. Jarvis, A. Jenkins, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, S. Kappler, D. Karmanov, J. Kasper, P. Kasper, I. Katsanos, D. Kau, R. Kaur, R. Kehoe, S. Kermiche, S. Kesisoglou, N. Khalatyan, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, M.H. Kirby, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, J. Kotcher, B. Kothari, A. Koubarovsky, A.V. Kozelov, J. Kozminski, A. Kryemadhi, S. Krzywdzinski, T. Kuhl, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, S. Lager, S. Lammers, G. Landsberg, J. Lazoflores, A.-C. Le Bihan, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, V. Lesne, J. Leveque, P. Lewis, J. Li, Q.Z. Li, J.G.R. Lima, D. Lincoln, J. Linnemann, V.V. Lipaev, R. Lipton, Z. Liu, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, M. Lynker, A.L. Lyon, A.K.A. Maciel, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, A.-M. Magnan, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, M. Martens, S.E.K. Mattingly, R. McCarthy, R. McCroskey, D. Meder, A. Melnitchouk, A. Mendes, L. Mendoza, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, H. Miettinen, T. Millet, J. Mitrevski, J. Molina, N.K. Mondal, J. Monk, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, M. Mulhearn, L. Mundim, Y.D. Mutaf, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, S. Nelson, P. Neustroev, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, V. O'Dell, D.C. O'Neil, G. Obrant, V. Oguri, N. Oliveira, N. Oshima, R. Otec, G.J. Otero y Garzón, M. Owen, P. Padley, N. Parashar, S.-J. Park, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, E. Perez, K. Peters, P. Pétroff, M. Petteni, R. Piegaia, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, A.V. Popov, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, K.J. Rani, K. Ranjan, P.A. Rapidis, P.N. Ratoff, P. Renkel, S. Reucroft, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, V.I. Rud, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, W.D. Shephard, R.K. Shivpuri, D. Shpakov, V. Siccardi, R.A. Sidwell, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, R.P. Smith, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, X. Song, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, K. Stevenson, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, A. Sznajder, M. Talby, P. Tamburello, W. Taylor, P. Telford, J. Temple, B. Tiller, M. Titov, V.V. Tokmenin, M. Tomoto, T. Toole, I. Torchiani, S. Towers, T. Trefzger, S. Trincaz-Duvoid, D. Tsybychev, B. Tuchming, C. Tully, A.S. Turcot, P.M. Tuts, R. Unalan, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, P. Vint, J.-R. Vlimant, E. Von Toerne, M. Voutilainen, M. Vreeswijk, H.D. Wahl, L. Wang, J. Warchol, G. Watts, M. Wayne, M. Weber, H. Weerts, N. Wermes, M. Wetstein, A. White, D. Wicke, G.W. Wilson, S.J. Wimpenny, M. Wobisch, J. Womersley, D.R. Wood, T.R. Wyatt, Y. Xie, N. Xuan, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, K. Yip, H.D. Yoo, S.W. Youn, C. Yu, J. Yu, A. Yurkewicz, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, Z. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, V. Zutshi, and E.G. Zverev
Subjects: Physics, Nuclear and High Energy Physics, Range (particle radiation), Particle physics, Photon, 010308 nuclear & particles physics, Branching fraction, Tevatron, 7. Clean energy, 01 natural sciences, law.invention, Cross section (physics), law, 0103 physical sciences, High Energy Physics::Experiment, Fermilab, Invariant (mathematics), 010306 general physics, Collider
Abstract: We present the results of a search for a new particle X produced in p p ¯ collisions at s = 1.96 TeV and subsequently decaying to Zγ. The search uses 0.3 fb−1 of data collected with the DO detector at the Fermilab Tevatron Collider. We set limits on the production cross section times the branching fraction σ ( p p ¯ → X ) × B ( X → Z γ ) that range from 0.4 to 3.5 pb at the 95% C.L. for X with invariant masses between 100 and 1000 GeV / c 2 , over a wide range of X decay widths.
Published: 2006

267. Search for W′ boson production in the W′→tb¯ decay channel

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, M. Agelou, J.-L. Agram, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, T. Andeen, S. Anderson, B. Andrieu, M.S. Anzelc, Y. Arnoud, M. Arov, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C. Ay, F. Badaud, A. Baden, L. Bagby, B. Baldin, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, P. Bargassa, P. Baringer, C. Barnes, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, A. Bean, M. Begalli, M. Begel, C. Belanger-Champagne, L. Bellantoni, A. Bellavance, J.A. Benitez, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, M. Binder, C. Biscarat, K.M. Black, I. Blackler, G. Blazey, F. Blekman, S. Blessing, D. Bloch, K. Bloom, U. Blumenschein, A. Boehnlein, O. Boeriu, T.A. Bolton, G. Borissov, K. Bos, E.E. Boos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, V. Bunichev, S. Burdin, S. Burke, T.H. Burnett, E. Busato, C.P. Buszello, J.M. Butler, P. Calfayan, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K.M. Chan, A. Chandra, D. Chapin, F. Charles, E. Cheu, F. Chevallier, D.K. Cho, S. Choi, B. Choudhary, L. Christofek, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, D. Coppage, M. Corcoran, M.-C. Cousinou, B. Cox, S. Crépé-Renaudin, D. Cutts, M. Ćwiok, H. da Motta, A. Das, M. Das, B. Davies, G. Davies, G.A. Davis, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, P. Demine, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, M. Doidge, A. Dominguez, H. Dong, L.V. Dudko, L. Duflot, S.R. Dugad, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, T. Edwards, J. Ellison, J. Elmsheuser, V.D. Elvira, S. Eno, P. Ermolov, J. Estrada, H. Evans, A. Evdokimov, V.N. Evdokimov, S.N. Fatakia, L. Feligioni, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, I. Fleck, M. Ford, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, J. Gardner, V. Gavrilov, A. Gay, P. Gay, D. Gelé, R. Gelhaus, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, N. Gollub, B. Gómez, A. Goussiou, P.D. Grannis, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, S. Grünendahl, M.W. Grünewald, F. Guo, J. Guo, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, P. Haefner, S. Hagopian, J. Haley, I. Hall, R.E. Hall, L. Han, K. Hanagaki, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, H. Hoeth, M. Hohlfeld, S.J. Hong, R. Hooper, P. Houben, Y. Hu, Z. Hubacek, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, K. Jakobs, C. Jarvis, A. Jenkins, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, S. Kappler, D. Karmanov, J. Kasper, P. Kasper, I. Katsanos, D. Kau, R. Kaur, R. Kehoe, S. Kermiche, S. Kesisoglou, N. Khalatyan, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, M.H. Kirby, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, J. Kotcher, B. Kothari, A. Koubarovsky, A.V. Kozelov, J. Kozminski, D. Krop, A. Kryemadhi, T. Kuhl, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, S. Lager, S. Lammers, G. Landsberg, J. Lazoflores, A.-C. Le Bihan, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, V. Lesne, J. Leveque, P. Lewis, J. Li, Q.Z. Li, J.G.R. Lima, D. Lincoln, J. Linnemann, V.V. Lipaev, R. Lipton, Z. Liu, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, M. Lynker, A.L. Lyon, A.K.A. Maciel, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, A.-M. Magnan, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, M. Martens, S.E.K. Mattingly, R. McCarthy, D. Meder, A. Melnitchouk, A. Mendes, L. Mendoza, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, H. Miettinen, T. Millet, J. Mitrevski, J. Molina, N.K. Mondal, J. Monk, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, M. Mulhearn, L. Mundim, Y.D. Mutaf, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, S. Nelson, P. Neustroev, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, V. O'Dell, D.C. O'Neil, G. Obrant, V. Oguri, N. Oliveira, N. Oshima, R. Otec, G.J. Otero y Garzón, M. Owen, P. Padley, N. Parashar, S.-J. Park, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, E. Perez, M. Perfilov, K. Peters, P. Pétroff, M. Petteni, R. Piegaia, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, A.V. Popov, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, K.J. Rani, K. Ranjan, P.N. Ratoff, P. Renkel, S. Reucroft, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, V.I. Rud, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, W.D. Shephard, R.K. Shivpuri, D. Shpakov, V. Siccardi, R.A. Sidwell, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, R.P. Smith, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, X. Song, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, A. Sznajder, M. Talby, P. Tamburello, W. Taylor, P. Telford, J. Temple, B. Tiller, M. Titov, V.V. Tokmenin, M. Tomoto, T. Toole, I. Torchiani, S. Towers, T. Trefzger, S. Trincaz-Duvoid, D. Tsybychev, B. Tuchming, C. Tully, A.S. Turcot, P.M. Tuts, R. Unalan, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, P. Vint, J.-R. Vlimant, E. Von Toerne, M. Voutilainen, M. Vreeswijk, H.D. Wahl, L. Wang, J. Warchol, G. Watts, M. Wayne, M. Weber, H. Weerts, N. Wermes, M. Wetstein, A. White, D. Wicke, G.W. Wilson, S.J. Wimpenny, M. Wobisch, J. Womersley, D.R. Wood, T.R. Wyatt, Y. Xie, N. Xuan, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, K. Yip, H.D. Yoo, S.W. Youn, C. Yu, J. Yu, A. Yurkewicz, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, V. Zutshi, and E.G. Zverev
Subjects: Quark, Physics, Nuclear and High Energy Physics, Gauge boson, Top quark, Particle physics, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Scalar boson, 7. Clean energy, 01 natural sciences, Bottom quark, Standard Model, Nuclear physics, W and Z bosons, 0103 physical sciences, High Energy Physics::Experiment, 010306 general physics, Boson
Abstract: We present a search for the production of a new heavy gauge boson W' that decays to a top quark and a bottom quark. We have analyzed 230 pb(-1) of data collected with the DO detector at the Fermilab Tevatron collider at a center-of-mass energy of 1.96 TeV. No significant excess of events above the standard model expectation is found in any region of the final state invariant mass distribution. We set upper limits on the production cross section of W' bosons times branching ratio to top quarks at the 95% confidence level for several different W, boson masses. We exclude masses between 200 and 610 GeV for a W' boson with standard-model-like couplings, between 200 and 630 GeV for a W, boson with right-handed couplings that is allowed to decay to both leptons and quarks, and between 200 and 670 GeV for a W' boson with right-handed couplings that is only allowed to decay to quarks.
Published: 2006

268. Search for scalar leptoquarks in the acoplanar jet topology in pp¯ collisions at s=1.96 TeV

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, M. Agelou, J.-L. Agram, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, T. Andeen, S. Anderson, B. Andrieu, M.S. Anzelc, Y. Arnoud, M. Arov, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C. Ay, F. Badaud, A. Baden, L. Bagby, B. Baldin, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, P. Bargassa, P. Baringer, C. Barnes, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, A. Bean, M. Begalli, M. Begel, C. Belanger-Champagne, L. Bellantoni, A. Bellavance, J.A. Benitez, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, M. Binder, C. Biscarat, K.M. Black, I. Blackler, G. Blazey, F. Blekman, S. Blessing, D. Bloch, K. Bloom, U. Blumenschein, A. Boehnlein, O. Boeriu, T.A. Bolton, G. Borissov, K. Bos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, S. Burdin, S. Burke, T.H. Burnett, E. Busato, C.P. Buszello, J.M. Butler, P. Calfayan, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K.M. Chan, A. Chandra, D. Chapin, F. Charles, E. Cheu, F. Chevallier, D.K. Cho, S. Choi, B. Choudhary, L. Christofek, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, D. Coppage, M. Corcoran, M.-C. Cousinou, B. Cox, S. Crépé-Renaudin, D. Cutts, M. Ćwiok, H. da Motta, A. Das, M. Das, B. Davies, G. Davies, G.A. Davis, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, P. Demine, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, M. Doidge, A. Dominguez, H. Dong, L.V. Dudko, L. Duflot, S.R. Dugad, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, T. Edwards, J. Ellison, J. Elmsheuser, V.D. Elvira, S. Eno, P. Ermolov, J. Estrada, H. Evans, A. Evdokimov, V.N. Evdokimov, S.N. Fatakia, L. Feligioni, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, I. Fleck, M. Ford, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, J. Gardner, V. Gavrilov, A. Gay, P. Gay, D. Gelé, R. Gelhaus, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, N. Gollub, B. Gómez, A. Goussiou, P.D. Grannis, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, S. Grünendahl, M.W. Grünewald, F. Guo, J. Guo, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, P. Haefner, S. Hagopian, J. Haley, I. Hall, R.E. Hall, L. Han, K. Hanagaki, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, H. Hoeth, M. Hohlfeld, S.J. Hong, R. Hooper, P. Houben, Y. Hu, Z. Hubacek, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, K. Jakobs, C. Jarvis, A. Jenkins, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, S. Kappler, D. Karmanov, J. Kasper, P. Kasper, I. Katsanos, D. Kau, R. Kaur, R. Kehoe, S. Kermiche, S. Kesisoglou, N. Khalatyan, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, M.H. Kirby, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, J. Kotcher, B. Kothari, A. Koubarovsky, A.V. Kozelov, J. Kozminski, D. Krop, A. Kryemadhi, T. Kuhl, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, S. Lager, S. Lammers, G. Landsberg, J. Lazoflores, A.-C. Le Bihan, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, V. Lesne, J. Leveque, P. Lewis, J. Li, Q.Z. Li, J.G.R. Lima, D. Lincoln, J. Linnemann, V.V. Lipaev, R. Lipton, Z. Liu, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, M. Lynker, A.L. Lyon, A.K.A. Maciel, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, A.-M. Magnan, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, M. Martens, S.E.K. Mattingly, R. McCarthy, D. Meder, A. Melnitchouk, A. Mendes, L. Mendoza, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, H. Miettinen, T. Millet, J. Mitrevski, J. Molina, N.K. Mondal, J. Monk, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, M. Mulhearn, L. Mundim, Y.D. Mutaf, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, S. Nelson, P. Neustroev, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, V. O'Dell, D.C. O'Neil, G. Obrant, V. Oguri, N. Oliveira, N. Oshima, R. Otec, G.J. Otero y Garzón, M. Owen, P. Padley, N. Parashar, S.-J. Park, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, E. Perez, K. Peters, P. Pétroff, M. Petteni, R. Piegaia, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, A.V. Popov, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, K.J. Rani, K. Ranjan, P.N. Ratoff, P. Renkel, S. Reucroft, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, V.I. Rud, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, W.D. Shephard, R.K. Shivpuri, D. Shpakov, V. Siccardi, R.A. Sidwell, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, R.P. Smith, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, X. Song, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, A. Sznajder, M. Talby, P. Tamburello, W. Taylor, P. Telford, J. Temple, B. Tiller, M. Titov, V.V. Tokmenin, M. Tomoto, T. Toole, I. Torchiani, S. Towers, T. Trefzger, S. Trincaz-Duvoid, D. Tsybychev, B. Tuchming, C. Tully, A.S. Turcot, P.M. Tuts, R. Unalan, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, P. Vint, J.-R. Vlimant, E. Von Toerne, M. Voutilainen, M. Vreeswijk, H.D. Wahl, L. Wang, J. Warchol, G. Watts, M. Wayne, M. Weber, H. Weerts, N. Wermes, M. Wetstein, A. White, D. Wicke, G.W. Wilson, S.J. Wimpenny, M. Wobisch, J. Womersley, D.R. Wood, T.R. Wyatt, Y. Xie, N. Xuan, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, K. Yip, H.D. Yoo, S.W. Youn, C. Yu, J. Yu, A. Yurkewicz, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, V. Zutshi, and E.G. Zverev
Subjects: Quark, Physics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Tevatron, Topology, 01 natural sciences, Standard Model, law.invention, Nuclear physics, law, 0103 physical sciences, High Energy Physics::Experiment, Leptoquark, Fermilab, Neutrino, 010306 general physics, Collider, Lepton
Abstract: A search for leptoquarks has been performed in 310 pb{sup -1} of data from p{bar p} collisions at a center-of-mass energy of 1.96 TeV, collected by the D0 detector at the Fermilab Tevatron Collider. The topology analyzed consists of acoplanar jets with missing transverse energy. The data show good agreement with standard model expectations, and a lower mass limit of 136 GeV has been set at the 95% C.L. for a scalar leptoquark decaying exclusively into a quark and a neutrino.
Published: 2006

269. Terminal mitoses require negative regulation of Fzr/Cdh1 by Cyclin A,preventing premature degradation of mitotic cyclins and String/Cdc25

Author: Henning W. Jacobs, Christian F. Lehner, and Achim Reber
Subjects: Embryo, Nonmammalian, Cyclin E, Cyclin D, Cyclin A, Cyclin B, Down-Regulation, Embryonic Development, Mitosis, Cell Cycle Proteins, Cdh1 Proteins, Cyclins, Animals, Drosophila Proteins, Molecular Biology, Cyclin-dependent kinase 1, biology, G1/S transition, Cell cycle, Cell biology, Mutation, biology.protein, Cancer research, Drosophila, Epidermis, Protein Tyrosine Phosphatases, Cyclin A2, Developmental Biology
Abstract: Cyclin A expression is only required for particular cell divisions during Drosophila embryogenesis. In the epidermis, Cyclin Ais strictly required for progression through mitosis 16 in cells that become post-mitotic after this division. By contrast, Cyclin A is not absolutely required in epidermal cells that are developmentally programmed for continuation of cell cycle progression after mitosis 16. Our analyses suggest the following explanation for the special Cyclin A requirement during terminal division cycles. Cyclin E is known to be downregulated during terminal division cycles to allow a timely cell cycle exit after the final mitosis. Cyclin E is therefore no longer available before terminal mitoses to prevent premature Fizzy-related/Cdh1 activation. As a consequence,Cyclin A, which can also function as a negative regulator of Fizzy-related/Cdh1, becomes essential to provide this inhibition before terminal mitoses. In the absence of Cyclin A, premature Fizzy-related/Cdh1 activity results in the premature degradation of the Cdk1 activators Cyclin B and Cyclin B3, and apparently of String/Cdc25 phosphatase as well. Without these activators, entry into terminal mitoses is not possible. However, entry into terminal mitoses can be restored by the simultaneous expression of versions of Cyclin B and Cyclin B3 without destruction boxes, along with a Cdk1 mutant that escapes inhibitory phosphorylation on T14 and Y15. Moreover,terminal mitoses are also restored in Cyclin A mutants by either the elimination of Fizzy-related/Cdh1 function or Cyclin Eoverexpression.
Published: 2006

270. Measurement of the isolated photon cross section in pp¯ collisions at s=1.96 TeV

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, M. Agelou, J.-L. Agram, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, T. Andeen, S. Anderson, B. Andrieu, Y. Arnoud, M. Arov, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, F. Badaud, A. Baden, L. Bagby, B. Baldin, P.W. Balm, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, P. Bargassa, P. Baringer, C. Barnes, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, A. Bean, S. Beauceron, M. Begalli, M. Begel, A. Bellavance, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, M. Binder, C. Biscarat, K.M. Black, I. Blackler, G. Blazey, F. Blekman, S. Blessing, D. Bloch, U. Blumenschein, A. Boehnlein, O. Boeriu, T.A. Bolton, F. Borcherding, G. Borissov, K. Bos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, S. Burdin, S. Burke, T.H. Burnett, E. Busato, C.P. Buszello, J.M. Butler, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K.M. Chan, A. Chandra, D. Chapin, F. Charles, E. Cheu, D.K. Cho, S. Choi, B. Choudhary, T. Christiansen, L. Christofek, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, D. Coppage, M. Corcoran, M.-C. Cousinou, B. Cox, S. Crépé-Renaudin, D. Cutts, H. da Motta, A. Das, M. Das, B. Davies, G. Davies, G.A. Davis, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, S. Dean, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, P. Demine, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, M. Doidge, H. Dong, S. Doulas, L.V. Dudko, L. Duflot, S.R. Dugad, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, T. Edwards, J. Ellison, J. Elmsheuser, V.D. Elvira, S. Eno, P. Ermolov, J. Estrada, H. Evans, A. Evdokimov, V.N. Evdokimov, J. Fast, S.N. Fatakia, L. Feligioni, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, I. Fleck, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, J. Gardner, V. Gavrilov, A. Gay, P. Gay, D. Gelé, R. Gelhaus, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, T. Golling, N. Gollub, B. Gómez, K. Gounder, A. Goussiou, P.D. Grannis, S. Greder, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, S. Grünendahl, M.W. Grünewald, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, S. Hagopian, J. Haley, I. Hall, R.E. Hall, C. Han, L. Han, K. Hanagaki, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, M. Hohlfeld, S.J. Hong, R. Hooper, P. Houben, Y. Hu, J. Huang, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, V. Jain, K. Jakobs, C. Jarvis, A. Jenkins, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, D. Karmanov, J. Kasper, I. Katsanos, D. Kau, R. Kaur, R. Kehoe, S. Kermiche, S. Kesisoglou, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, J. Kotcher, B. Kothari, A. Koubarovsky, A.V. Kozelov, J. Kozminski, A. Kryemadhi, S. Krzywdzinski, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, S. Lager, S. Lammers, G. Landsberg, J. Lazoflores, A.-C. Le Bihan, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, C. Leonidopoulos, V. Lesne, J. Leveque, P. Lewis, J. Li, Q.Z. Li, J.G.R. Lima, D. Lincoln, S.L. Linn, J. Linnemann, V.V. Lipaev, R. Lipton, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, L. Lueking, M. Lynker, A.L. Lyon, A.K.A. Maciel, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, A.-M. Magnan, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, M. Martens, S.E.K. Mattingly, R. McCarthy, R. McCroskey, D. Meder, A. Melnitchouk, A. Mendes, L. Mendoza, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, H. Miettinen, J. Mitrevski, J. Molina, N.K. Mondal, J. Monk, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, L. Mundim, Y.D. Mutaf, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, S. Nelson, P. Neustroev, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, E. Nurse, V. O'Dell, D.C. O'Neil, G. Obrant, V. Oguri, N. Oliveira, N. Oshima, G.J. Otero y Garzón, P. Padley, N. Parashar, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, E. Perez, P. Pétroff, M. Petteni, R. Piegaia, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, K.J. Rani, K. Ranjan, P.A. Rapidis, P.N. Ratoff, S. Reucroft, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, V.I. Rud, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, W.D. Shephard, R.K. Shivpuri, D. Shpakov, R.A. Sidwell, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, R.P. Smith, K. Smolek, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, X. Song, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, K. Stevenson, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, A. Sznajder, M. Talby, P. Tamburello, W. Taylor, P. Telford, J. Temple, B. Tiller, M. Titov, M. Tomoto, T. Toole, I. Torchiani, S. Towers, T. Trefzger, S. Trincaz-Duvoid, D. Tsybychev, B. Tuchming, C. Tully, A.S. Turcot, P.M. Tuts, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, J.-R. Vlimant, E. Von Toerne, M. Voutilainen, M. Vreeswijk, T. Vu Anh, H.D. Wahl, L. Wang, J. Warchol, G. Watts, M. Wayne, M. Weber, H. Weerts, N. Wermes, M. Wetstein, A. White, V. White, D. Wicke, D.A. Wijngaarden, G.W. Wilson, S.J. Wimpenny, M. Wobisch, J. Womersley, D.R. Wood, T.R. Wyatt, Y. Xie, Q. Xu, N. Xuan, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, Y. Yen, K. Yip, H.D. Yoo, S.W. Youn, J. Yu, A. Yurkewicz, A. Zabi, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, Z. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, V. Zutshi, and E.G. Zverev
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Photon, 010308 nuclear & particles physics, Tevatron, Perturbative QCD, 7. Clean energy, 01 natural sciences, Nuclear physics, Transverse plane, Pseudorapidity, 0103 physical sciences, High Energy Physics::Experiment, Fermilab, Nuclear Experiment, 010306 general physics
Abstract: The cross section for the inclusive production of isolated photons has been measured in p anti-p collisions at sqrt{s}=1.96 TeV with the D0 detector at the Fermilab Tevatron Collider. The photons span transverse momenta 23 to 300 GeV and have pseudorapidity |eta
Published: 2006

271. Measurement of B(t→Wb)/B(t→Wq) at s=1.96TeV

Author: V. Simak, F. Villeneuve-Seguier, Vipin Bhatnagar, E. De La Cruz-Burelo, R. Partridge, Christian Autermann, V. L. Malyshev, V. V. Tokmenin, P. Padley, H. S. Mao, R. F. Rodrigues, B. Åsman, R. Van Kooten, V. M. Abazov, M. D. Corcoran, G. Obrant, V. Shary, Mitchell Wayne, H. Schellman, J. M. Kohli, A. C.S. Assis Jesus, Guennadi Borissov, H. A. Neal, D. Meder, J. T. Linnemann, K. Yip, N. Xuan, Stefan Grünendahl, D. Brown, Christian Schmitt, S. Nelson, M. H.G. Souza, W. C. Fisher, P. Verdier, K. J. Rani, A. Alton, M. Merkin, Robert Hirosky, K. W. Merritt, J. F. Bartlett, P. Banerjee, Armen Vartapetian, A. P. Heinson, G. S. Muanza, Stephen Wimpenny, Iain Alexander Bertram, R. Gelhaus, Michael Rijssenbeek, D. V. Bandurin, D. A. Stoyanova, Robert Kehoe, M. C. Cousinou, Marco Verzocchi, C. Magass, Dugan O'Neil, E. G. Zverev, A. Patwa, Mark Owen, Denis Gelé, Raymond Brock, Boaz Klima, M. Das, Sascha Caron, R. Unalan, L. Stutte, Gregory J Pawloski, L. Han, A. Zieminski, A.S. Dyshkant, Dmitri Tsybychev, R. L. McCarthy, I. Katsanos, N. M. Cason, M. Agelou, A. M. Magnan, M. Yan, S. Fu, R. Beuselinck, F. Borcherding, R. W. Moore, F. Lehner, T. Edwards, Martin Grunewald, A. M. Kalinin, Mossadek Talby, R. E. Hall, B. Gómez, Shashikant Dugad, A. Yurkewicz, Jiri Kvita, P. A. Rapidis, S. Burke, D. A. Wijngaarden, Marcia Begalli, M. Zielinski, Milos Lokajicek, L. Bagby, Christophe Royon, N. Gollub, A. Evdokimov, Terry Richard Wyatt, P. K. Mal, V. N. Evdokimov, I. Hall, M. Kopal, A. Chandra, Jovan Mitrevski, M. A. Strang, G. Hesketh, Norbert Wermes, Julia S. Meyer, Meenakshi Narain, Sherry Towers, J. Haley, Suyong Choi, Emily Nurse, G. Sajot, Elizabeth Gallas, V. I. Rud, S. Söldner-Rembold, Darien Wood, V. A. Bezzubov, M. Strovink, R. A. Sidwell, J. P. Negret, G. Gutierrez, R. P. Smith, P. J. Van Den Berg, Jessica Levêque, K. Bos, Marc Besancon, J. Temple, L. S. Vertogradov, Michael Begel, Sergey Burdin, M. Eads, K. M. Chan, Christian Zeitnitz, Lev Uvarov, Y. Hu, Gilvan Alves, Emanuela Barberis, M. Abolins, Sophie Trincaz-Duvoid, Nicholas John Hadley, C. P. Buszello, Kazunori Hanagaki, Dongliang Zhang, H. D. Wahl, Nikola Makovec, Rupinder Kaur, Bradley Cox, S. P. Denisov, J. D. Degenhardt, S. Lammers, Y. Arnoud, B. Davies, H. Weerts, J. Kozminski, S. Blessing, P. Renkel, Michael Hildreth, Eduardo De Moraes Gregores, S. E.K. Mattingly, Graham Wilson, Heriberto Castilla-Valdez, H. da Motta, S. Krzywdzinski, M. Petteni, J. Lazoflores, D. Edmunds, M. Binder, W. E. Cooper, Scott Snyder, D. Bauer, F. Badaud, Kevin Black, Cris W. Barnes, Yann Coadou, D. Kau, P.F. Ermolov, D. Gillberg, K. Stevenson, N. K. Mondal, P. Schieferdecker, H. T. Diehl, T. A. Bolton, Lev Dudko, Mikko Voutilainen, W. D. Shephard, R. McCroskey, Andre Sznajder, M. Cooke, Y. Pogorelov, S. Uzunyan, Karl Jakobs, R. K. Shivpuri, C. Noeding, A. S. Ito, A. Melnitchouk, A. Sanchez-Hernandez, A. Boehnlein, M. Sosebee, J. M. Kalk, Arnaud Duperrin, Yuri Gershtein, G. A. Davis, Boris Tuchming, Sharon Hagopian, Gregorio Bernardi, Emmanuelle Perez, A. K.A. Maciel, D. Denisov, W. L. Prado Da Silva, S. Greder, V. M. Korablev, Harrison Prosper, Y. Xie, Amnon Harel, S. Desai, V. Hynek, Jeroen Hegeman, J. Ellison, Jong-Sung Yu, Hwi Dong Yoo, B. Vachon, D. R. Claes, V. Zutshi, Gavin Davies, W. M. Van Leeuwen, C. Schwanenberger, M. Ahsan, J. M. Heinmiller, Sa. Jain, S. Fuess, Jun Guo, Q. Z. Li, Hal Evans, Thomas Ferbel, H. Greenlee, D. M. Strom, S. Doulas, L. Berntzon, Ashok Kumar, T. Kurca, S. Sengupta, Freya Blekman, Luiz Mundim, V. V. Lipaev, Lars Sonnenschein, M. S. Anzelc, Sarah Catherine Eno, Horst Severini, Marc Weber, S. Chakrabarti, Peter Love, E. Galyaev, B. C.K. Casey, V. Lesne, I. Ripp-Baudot, A. Meyer, S. J. Hong, Jonas Strandberg, N. Parua, Y. Scheglov, Kaushik De, M. H. Kirby, Reinhard Schwienhorst, R. Piegaia, Ariel Schwartzman, Michael A. Strauss, R. Bernhard, Limin Wang, A. Bross, Marc-Andre Pleier, P. Lewis, Ashok Das, Christos Leonidopoulos, T. Kuhl, G. Alkhazov, A. Jenkins, R. J. Madaras, S. Yacoob, J. A. Parsons, Paul Telford, V. White, I. Blackler, Avto Kharchilava, P. Lebrun, J. Snow, Christophe Clement, F. Charles, Andrew Brandt, N. Parashar, Serban Protopopescu, M. Jaffré, Tae Jeong Kim, Marcel Vreeswijk, B. Spurlock, O. Boeriu, F. Chevallier, T. Yasuda, Alexander Khanov, Sung Keun Park, Jan Stark, Wendy Taylor, J. Womersley, Zeno Dixon Greenwood, Kirti Ranjan, H.E. Miettinen, Carsten Hensel, Junjie Zhu, Henry Lubatti, Y. A. Yatsunenko, D. K. Cho, A. Stone, George Alverson, Johannes Elmsheuser, P. Neustroev, Tobias Golling, T. Scanlon, Andy Haas, S. Kermiche, M. Wobisch, Alexey Ferapontov, A. Pompoš, J. Cammin, Viatcheslav Stolin, Richard B. Lipton, Tulika Bose, Suman Bala Beri, D. Hedin, J. Kasper, K. Gounder, J. R. Kalk, P. Haefner, Vivian O'Dell, Mark Raymond Adams, Emmanuel Busato, M. Ćwiok, Cristina Galea, Alexander Kupco, D. Karmanov, Marvin Johnson, J. Molina, Carlos Avila, S. Sumowidagdo, Kristian Harder, S. Kesisoglou, O. Atramentov, Tiefu Zhao, V. Siccardi, A. Juste, Todd Adams, M. Wetstein, Sudhir Malik, A. V. Kozelov, Ia Iashvili, P. Skubic, Sabine Crépé-Renaudin, D. Cutts, Ulrike Blumenschein, Frederic Deliot, Christopher George Tully, Jean-Roch Vlimant, Brajesh C Choudhary, J. P. Konrath, H. Dong, Andrew White, D. Buchholz, Wagner Carvalho, M. Michaut, P. L.M. Podesta-Lerma, Jean-Laurent Agram, R. Otec, Randy Ruchti, D. Chakraborty, Greg Landsberg, Adam L. Lyon, G. Savage, Brad Abbott, A. Magerkurth, A. Zatserklyaniy, Y. M. Kharzheev, Sergio F Novaes, R. Jesik, Michael Martens, P. Tamburello, Juan Estrada, C. Ay, Pierre Petroff, B. S. Acharya, C. De Oliveira Martins, P. N. Ratoff, Nikos Varelas, Bing Zhou, Luis Mendoza, Patrick Slattery, G. J. Otero y Garzón, M. Ford, Andrew Askew, Zhengguo Zhao, Anna Goussiou, Abdenour Lounis, D. Shpakov, Pedrame Bargassa, P. M. Tuts, Maksym Titov, T. H. Burnett, Hyun-Chul Kim, Yurii Maravin, Don Lincoln, Erich Varnes, Vladimir Gavrilov, M. Anastasoaie, K. Soustruznik, K. A. Johns, Andrei Nomerotski, C. Jarvis, Gordon Watts, V. Sirotenko, S. N. Fatakia, Robert Harrington, Arnulf Quadt, J. Dyer, N. J. Buchanan, A. Mendes, Gregory R Snow, Elemer Nagy, J. A. Benitez, A. C. Le Bihan, V. M. Podstavkov, J. Monk, John Hobbs, A. Baden, J. Barreto, Ulrich Heintz, Md. Naimuddin, A. S. Turcot, Phillip Gutierrez, M. Fortner, B. Clement, G. C. Blazey, Y. Yen, I. Torchiani, M. Buehler, Frank Filthaut, T. Gadfort, M. Diesburg, M. Lynker, R. Hooper, D. Wicke, R. Yamada, X. F. Song, L. Lobo, T. Nunnemann, Ph Gris, B. Baldin, P. Houben, Lorenzo Feligioni, Jean-Francois Grivaz, S. H. Ahn, P. de Jong, M. Arov, Dorothee Schaile, V. Oguri, A. Koubarovsky, P. Jonsson, Mansoora Shamim, Jing Li, A. V. Popov, M. Hohlfeld, Thomas Hebbeker, D. Khatidze, M. Mulders, J. Hays, Gustaaf Brooijmans, J. Warchol, V. Buescher, S. J. De Jong, B. Kothari, A. A. Shchukin, Andre Sopczak, Frank Fiedler, E. Kajfasz, H. E. Fisk, Aran Garcia-Bellido, M. P. Sanders, J. M. Hauptman, Cecilia Elena Gerber, G. Ginther, Jianming Qian, M. Doidge, B. Andrieu, Elliott Cheu, Victor Daniel Elvira, U. Bassler, S. Robinson, Regina Demina, T. Moulik, Alberto Santoro, J. G.R. Lima, W. M. Lee, P. Rubinov, L. Christofek, Helena Malbouisson, D. Chapin, J. N. Butler, P. D. Grannis, J. Steele, B. Tiller, S. W. Youn, E. Von Toerne, P. Demine, D. Coppage, G. Grenier, N. A. Naumann, Pushpalatha C Bhat, S. Reucroft, Reiner Hauser, D. Käfer, A. Bellavance, B. Hoeneisen, Lee Sawyer, B. G. Pope, Calvin A. Johnson, S. Calvet, Elizaveta Shabalina, Timothy Andeen, A. Kryemadhi, Shuichi Kunori, P. Mättig, R. Illingworth, A. Leflat, S.A. Kahn, Philip Baringer, S. Jabeen, S. Banerjee, M. Demarteau, Carmen García, T. Toole, S. Lager, S. Uvarov, Ivor Fleck, B. Quinn, Thomas Trefzger, Makoto Tomoto, Alice Bean, N. Oliveira, Maria Elena Pol, J. Gardner, J. Kotcher, S. Anderson, Harald Fox, M. Vaupel, Y. D. Mutaf, I. A. Vasilyev, P. M. Perea, G. D. Alexeev, Flera Rizatdinova, C. Biscarat, A. Jonckheere, A. Lobodenko, N. Oshima, Daniel Bloch, Daria Zieminska, R. D. Schamberger, Raimund Ströhmer, and L. Duflot
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Top quark, Muon, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Tevatron, Electron, 7. Clean energy, 01 natural sciences, Lower limit, Standard Model, law.invention, Nuclear physics, law, 0103 physical sciences, High Energy Physics::Experiment, Fermilab, 010306 general physics, Collider
Abstract: We present the measurement of R = B(t -> Wb)/B(t -> Wq) in pp collisions at root s = 1.96 TeV, using 230 pb(-1) of data collected by the DO experiment at the Fermilab Tevatron Collider. We fit simultaneously R and the number (N-tt) of selected top quark pairs (tt), to the number of identified b-quark jets in events with one electron or one muon, three or more jets, and high transverse energy imbalance. To improve sensitivity, kinematical properties of events with no identified b-quark jets are included in the fit. We measure R = 1.03(-0.17)(0.19) (stat + syst), in good agreement with the standard model. We set lower limits of R > 0.61 and vertical bar V-tb vertical bar > 0.78 at 95% confidence level.
Published: 2006

272. Search for R-parity violating supersymmetry via the LLE¯ couplings λ121, λ122 or λ133 in pp¯ collisions at s=1.96 TeV

Author: V.M. Abazov, B. Abbott, M. Abolins, B.S. Acharya, M. Adams, T. Adams, M. Agelou, J.-L. Agram, S.H. Ahn, M. Ahsan, G.D. Alexeev, G. Alkhazov, A. Alton, G. Alverson, G.A. Alves, M. Anastasoaie, T. Andeen, S. Anderson, B. Andrieu, M.S. Anzelc, Y. Arnoud, M. Arov, A. Askew, B. Åsman, A.C.S. Assis Jesus, O. Atramentov, C. Autermann, C. Avila, C. Ay, F. Badaud, A. Baden, L. Bagby, B. Baldin, D.V. Bandurin, P. Banerjee, S. Banerjee, E. Barberis, P. Bargassa, P. Baringer, C. Barnes, J. Barreto, J.F. Bartlett, U. Bassler, D. Bauer, A. Bean, M. Begalli, M. Begel, C. Belanger-Champagne, L. Bellantoni, A. Bellavance, J.A. Benitez, S.B. Beri, G. Bernardi, R. Bernhard, L. Berntzon, I. Bertram, M. Besançon, R. Beuselinck, V.A. Bezzubov, P.C. Bhat, V. Bhatnagar, M. Binder, C. Biscarat, K.M. Black, I. Blackler, G. Blazey, F. Blekman, S. Blessing, D. Bloch, K. Bloom, U. Blumenschein, A. Boehnlein, O. Boeriu, T.A. Bolton, F. Borcherding, G. Borissov, K. Bos, T. Bose, A. Brandt, R. Brock, G. Brooijmans, A. Bross, D. Brown, N.J. Buchanan, D. Buchholz, M. Buehler, V. Buescher, S. Burdin, S. Burke, T.H. Burnett, E. Busato, C.P. Buszello, J.M. Butler, P. Calfayan, S. Calvet, J. Cammin, S. Caron, W. Carvalho, B.C.K. Casey, N.M. Cason, H. Castilla-Valdez, S. Chakrabarti, D. Chakraborty, K.M. Chan, A. Chandra, D. Chapin, F. Charles, E. Cheu, F. Chevallier, D.K. Cho, S. Choi, B. Choudhary, L. Christofek, D. Claes, B. Clément, C. Clément, Y. Coadou, M. Cooke, W.E. Cooper, D. Coppage, M. Corcoran, M.-C. Cousinou, B. Cox, S. Crépé-Renaudin, D. Cutts, M. Ćwiok, H. da Motta, A. Das, M. Das, B. Davies, G. Davies, G.A. Davis, K. De, P. de Jong, S.J. de Jong, E. De La Cruz-Burelo, C. De Oliveira Martins, J.D. Degenhardt, F. Déliot, M. Demarteau, R. Demina, P. Demine, D. Denisov, S.P. Denisov, S. Desai, H.T. Diehl, M. Diesburg, M. Doidge, A. Dominguez, H. Dong, L.V. Dudko, L. Duflot, S.R. Dugad, A. Duperrin, J. Dyer, A. Dyshkant, M. Eads, D. Edmunds, T. Edwards, J. Ellison, J. Elmsheuser, V.D. Elvira, S. Eno, P. Ermolov, J. Estrada, H. Evans, A. Evdokimov, V.N. Evdokimov, S.N. Fatakia, L. Feligioni, A.V. Ferapontov, T. Ferbel, F. Fiedler, F. Filthaut, W. Fisher, H.E. Fisk, I. Fleck, M. Ford, M. Fortner, H. Fox, S. Fu, S. Fuess, T. Gadfort, C.F. Galea, E. Gallas, E. Galyaev, C. Garcia, A. Garcia-Bellido, J. Gardner, V. Gavrilov, A. Gay, P. Gay, D. Gelé, R. Gelhaus, C.E. Gerber, Y. Gershtein, D. Gillberg, G. Ginther, N. Gollub, B. Gómez, K. Gounder, A. Goussiou, P.D. Grannis, H. Greenlee, Z.D. Greenwood, E.M. Gregores, G. Grenier, Ph. Gris, J.-F. Grivaz, S. Grünendahl, M.W. Grünewald, F. Guo, J. Guo, G. Gutierrez, P. Gutierrez, A. Haas, N.J. Hadley, P. Haefner, S. Hagopian, J. Haley, I. Hall, R.E. Hall, L. Han, K. Hanagaki, K. Harder, A. Harel, R. Harrington, J.M. Hauptman, R. Hauser, J. Hays, T. Hebbeker, D. Hedin, J.G. Hegeman, J.M. Heinmiller, A.P. Heinson, U. Heintz, C. Hensel, G. Hesketh, M.D. Hildreth, R. Hirosky, J.D. Hobbs, B. Hoeneisen, H. Hoeth, M. Hohlfeld, S.J. Hong, R. Hooper, P. Houben, Y. Hu, Z. Hubacek, V. Hynek, I. Iashvili, R. Illingworth, A.S. Ito, S. Jabeen, M. Jaffré, S. Jain, K. Jakobs, C. Jarvis, A. Jenkins, R. Jesik, K. Johns, C. Johnson, M. Johnson, A. Jonckheere, P. Jonsson, A. Juste, D. Käfer, S. Kahn, E. Kajfasz, A.M. Kalinin, J.M. Kalk, J.R. Kalk, S. Kappler, D. Karmanov, J. Kasper, P. Kasper, I. Katsanos, D. Kau, R. Kaur, R. Kehoe, S. Kermiche, S. Kesisoglou, N. Khalatyan, A. Khanov, A. Kharchilava, Y.M. Kharzheev, D. Khatidze, H. Kim, T.J. Kim, M.H. Kirby, B. Klima, J.M. Kohli, J.-P. Konrath, M. Kopal, V.M. Korablev, J. Kotcher, B. Kothari, A. Koubarovsky, A.V. Kozelov, J. Kozminski, A. Kryemadhi, S. Krzywdzinski, T. Kuhl, A. Kumar, S. Kunori, A. Kupco, T. Kurča, J. Kvita, S. Lager, S. Lammers, G. Landsberg, J. Lazoflores, A.-C. Le Bihan, P. Lebrun, W.M. Lee, A. Leflat, F. Lehner, V. Lesne, J. Leveque, P. Lewis, J. Li, Q.Z. Li, J.G.R. Lima, D. Lincoln, J. Linnemann, V.V. Lipaev, R. Lipton, Z. Liu, L. Lobo, A. Lobodenko, M. Lokajicek, A. Lounis, P. Love, H.J. Lubatti, M. Lynker, A.L. Lyon, A.K.A. Maciel, R.J. Madaras, P. Mättig, C. Magass, A. Magerkurth, A.-M. Magnan, N. Makovec, P.K. Mal, H.B. Malbouisson, S. Malik, V.L. Malyshev, H.S. Mao, Y. Maravin, M. Martens, S.E.K. Mattingly, R. McCarthy, R. McCroskey, D. Meder, A. Melnitchouk, A. Mendes, L. Mendoza, M. Merkin, K.W. Merritt, A. Meyer, J. Meyer, M. Michaut, H. Miettinen, T. Millet, J. Mitrevski, J. Molina, N.K. Mondal, J. Monk, R.W. Moore, T. Moulik, G.S. Muanza, M. Mulders, M. Mulhearn, L. Mundim, Y.D. Mutaf, E. Nagy, M. Naimuddin, M. Narain, N.A. Naumann, H.A. Neal, J.P. Negret, S. Nelson, P. Neustroev, C. Noeding, A. Nomerotski, S.F. Novaes, T. Nunnemann, V. O'Dell, D.C. O'Neil, G. Obrant, V. Oguri, N. Oliveira, N. Oshima, R. Otec, G.J. Otero y Garzón, M. Owen, P. Padley, N. Parashar, S.-J. Park, S.K. Park, J. Parsons, R. Partridge, N. Parua, A. Patwa, G. Pawloski, P.M. Perea, E. Perez, K. Peters, P. Pétroff, M. Petteni, R. Piegaia, M.-A. Pleier, P.L.M. Podesta-Lerma, V.M. Podstavkov, Y. Pogorelov, M.-E. Pol, A. Pompoš, B.G. Pope, A.V. Popov, W.L. Prado da Silva, H.B. Prosper, S. Protopopescu, J. Qian, A. Quadt, B. Quinn, K.J. Rani, K. Ranjan, P.A. Rapidis, P.N. Ratoff, P. Renkel, S. Reucroft, M. Rijssenbeek, I. Ripp-Baudot, F. Rizatdinova, S. Robinson, R.F. Rodrigues, C. Royon, P. Rubinov, R. Ruchti, V.I. Rud, G. Sajot, A. Sánchez-Hernández, M.P. Sanders, A. Santoro, G. Savage, L. Sawyer, T. Scanlon, D. Schaile, R.D. Schamberger, Y. Scheglov, H. Schellman, P. Schieferdecker, C. Schmitt, C. Schwanenberger, A. Schwartzman, R. Schwienhorst, S. Sengupta, H. Severini, E. Shabalina, M. Shamim, V. Shary, A.A. Shchukin, W.D. Shephard, R.K. Shivpuri, D. Shpakov, V. Siccardi, R.A. Sidwell, V. Simak, V. Sirotenko, P. Skubic, P. Slattery, R.P. Smith, G.R. Snow, J. Snow, S. Snyder, S. Söldner-Rembold, X. Song, L. Sonnenschein, A. Sopczak, M. Sosebee, K. Soustruznik, M. Souza, B. Spurlock, J. Stark, J. Steele, K. Stevenson, V. Stolin, A. Stone, D.A. Stoyanova, J. Strandberg, M.A. Strang, M. Strauss, R. Ströhmer, D. Strom, M. Strovink, L. Stutte, S. Sumowidagdo, A. Sznajder, M. Talby, P. Tamburello, W. Taylor, P. Telford, J. Temple, B. Tiller, M. Titov, V.V. Tokmenin, M. Tomoto, T. Toole, I. Torchiani, S. Towers, T. Trefzger, S. Trincaz-Duvoid, D. Tsybychev, B. Tuchming, C. Tully, A.S. Turcot, P.M. Tuts, R. Unalan, L. Uvarov, S. Uvarov, S. Uzunyan, B. Vachon, P.J. van den Berg, R. Van Kooten, W.M. van Leeuwen, N. Varelas, E.W. Varnes, A. Vartapetian, I.A. Vasilyev, M. Vaupel, P. Verdier, L.S. Vertogradov, M. Verzocchi, F. Villeneuve-Seguier, P. Vint, J.-R. Vlimant, E. Von Toerne, M. Voutilainen, M. Vreeswijk, H.D. Wahl, L. Wang, J. Warchol, G. Watts, M. Wayne, M. Weber, H. Weerts, N. Wermes, M. Wetstein, A. White, D. Wicke, G.W. Wilson, S.J. Wimpenny, M. Wobisch, J. Womersley, D.R. Wood, T.R. Wyatt, Y. Xie, N. Xuan, S. Yacoob, R. Yamada, M. Yan, T. Yasuda, Y.A. Yatsunenko, K. Yip, H.D. Yoo, S.W. Youn, C. Yu, J. Yu, A. Yurkewicz, A. Zatserklyaniy, C. Zeitnitz, D. Zhang, T. Zhao, Z. Zhao, B. Zhou, J. Zhu, M. Zielinski, D. Zieminska, A. Zieminski, V. Zutshi, and E.G. Zverev
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Gaugino, Tevatron, Supersymmetry, Lambda, 7. Clean energy, 01 natural sciences, Nuclear physics, Chargino, Pair production, R-parity, 0103 physical sciences, Neutralino, High Energy Physics::Experiment, 010306 general physics
Abstract: A search for gaugino pair production with a trilepton signature in the framework of R-parity violating supersymmetry via the couplings lambda_121, lambda_122, or lambda_133 is presented. The data, corresponding to an integrated luminosity of L~360/pb, were collected from April 2002 to August 2004 with the D0 detector at the Fermilab Tevatron Collider, at a center-of-mass energy of sqrt(s)=1.96 TeV. This analysis considers final states with three charged leptons with the flavor combinations eel, mumul, and eetau (l=e or mu). No evidence for supersymmetry is found and limits at the 95% confidence level are set on the gaugino pair production cross section and lower bounds on the masses of the lightest neutralino and chargino are derived in two supersymmetric models.
Published: 2006

273. Search for squarks and gluinos in events with jets and missing transverse energy in pp¯ collisions at s=1.96 TeV

Author: A. Baden, G. C. Blazey, J. P. Konrath, T. H. Burnett, Graham Wilson, H. da Motta, H. Dong, I. Torchiani, D. Buchholz, R. Yamada, D. Gillberg, Thomas Trefzger, P. Tamburello, Jean-Francois Grivaz, S. H. Ahn, P. de Jong, J. A. Benitez, Z. Liu, A. S. Ito, A. Melnitchouk, M. Arov, V. A. Bezzubov, J. P. Negret, R. P. Smith, Jonas Strandberg, N. Parua, P. Jonsson, Anna Goussiou, Ulrich Heintz, Stephen Wimpenny, T. Kuhl, V. Hynek, M. Jaffré, J. Dyer, Sophie Trincaz-Duvoid, J. Kozminski, Michael Hildreth, Martin Grunewald, J. Kasper, Chris P. Barnes, G. D. Alexeev, Flera Rizatdinova, Thomas Hebbeker, D. Khatidze, M. Mulders, Gregory R Snow, Milos Lokajicek, Andrew White, M. Michaut, L. Duflot, D. Kau, V. V. Lipaev, Frank Filthaut, M. Diesburg, Alexander Kupco, F. Guo, W. M. Van Leeuwen, Randy Ruchti, K. Stevenson, S. Uzunyan, Darien Wood, V. Lesne, Nicholas John Hadley, C. P. Buszello, B. Åsman, R. Van Kooten, Harrison Prosper, Andrei Nomerotski, John Hobbs, Y. Xie, Amnon Harel, S. Desai, J. Barreto, P.F. Ermolov, Robert Hirosky, A. M. Kalinin, Kristian Harder, D. Bauer, Tae Jeong Kim, D. Cutts, Jovan Mitrevski, G. Gutierrez, Gilvan Alves, M. D. Corcoran, Wagner Carvalho, Greg Landsberg, Marvin Johnson, Nikola Makovec, T. Edwards, A. P. Heinson, G. S. Muanza, Aaron Dominguez, A. Chandra, S. Blessing, Scott Snyder, L. Han, A. V. Kozelov, R. E. Hall, M. Buehler, Sascha Caron, Karl Jakobs, A. Zieminski, Pedrame Bargassa, M. Wetstein, K. Soustruznik, N. J. Buchanan, M. Strovink, H. Weerts, M. Binder, Lev Dudko, C. Belanger-Champagne, Lev Uvarov, Hwi Dong Yoo, S. Sengupta, S. Lammers, V. V. Tokmenin, Terry Richard Wyatt, F. Borcherding, H. A. Neal, N. Gollub, P. A. Rapidis, D. Meder, C. Jarvis, P. Lewis, J. Snow, T. Nunnemann, B. Baldin, K. Peters, Christophe Clement, Mansoora Shamim, J. T. Linnemann, Elizabeth Gallas, Sergio F Novaes, G. Sajot, K. Gounder, Adam L. Lyon, S. Chakrabarti, M. A. Strang, F. Villeneuve-Seguier, K. Yip, N. Xuan, R. A. Sidwell, Sung Keun Park, Y. Hu, R. Unalan, M. Cooke, W. L. Prado Da Silva, I. Ripp-Baudot, A. Meyer, C. Noeding, Yurii Maravin, Vladimir Gavrilov, Gordon Watts, V. Sirotenko, A. C. Le Bihan, Md. Naimuddin, A. S. Turcot, Phillip Gutierrez, Christian Schmitt, S. Nelson, M. H.G. Souza, M. H. Kirby, G. Alkhazov, D. Chakraborty, J. R. Kalk, O. Atramentov, Peter Love, R. Bernhard, Pushpalatha C Bhat, Ariel Schwartzman, L. Stutte, Gregory J Pawloski, A.S. Dyshkant, Ashok Das, M. Lynker, Reiner Hauser, Don Lincoln, Erich Varnes, R. Gelhaus, R. J. Madaras, M. S. Anzelc, Sarah Catherine Eno, S. Yacoob, Jiri Kvita, Marco Verzocchi, C. Magass, Marcel Vreeswijk, B. Spurlock, Frederic Deliot, Zeno Dixon Greenwood, Christopher George Tully, X. F. Song, Suyong Choi, B. Hoeneisen, Lee Sawyer, J. Monk, Andre Sopczak, Horst Severini, K. J. Rani, A. Alton, S. E.K. Mattingly, Rupinder Kaur, Bradley Cox, Dugan O'Neil, E. G. Zverev, F. Chevallier, Armen Vartapetian, B. Andrieu, A. Patwa, Mark Owen, M. Anastasoaie, G. Savage, Elliott Cheu, Junjie Zhu, Dorothee Schaile, Denis Gelé, George Alverson, N. M. Cason, Victor Daniel Elvira, Christos Leonidopoulos, Chuanhua Yu, Cristina Galea, Johannes Elmsheuser, P. Neustroev, Richard B. Lipton, Juan Estrada, Emmanuel Busato, S.A. Kahn, M. Ćwiok, M. Hohlfeld, D. Hedin, Dmitri Tsybychev, R. L. McCarthy, S. Kesisoglou, S. J. Hong, Marcia Begalli, J. Womersley, M. Abolins, Jing Li, Norbert Wermes, R. Jesik, M. Kopal, M. Demarteau, L. Bagby, V. M. Abazov, V. Shary, Arnulf Quadt, M. Wobisch, Paul Telford, Avto Kharchilava, P. Renkel, S. Krzywdzinski, A. Pompoš, Meenakshi Narain, Sherry Towers, J. Haley, Carmen García, Elemer Nagy, A. Yurkewicz, R. Otec, Mark Raymond Adams, D. Karmanov, K. A. Johns, Sergey Burdin, M. Eads, T. Millet, Kevin Black, Alexander Khanov, L. Christofek, C. Biscarat, J. D. Degenhardt, Y. M. Kharzheev, N. K. Mondal, P. K. Mal, Patrick Slattery, G. J. Otero y Garzón, V. I. Rud, S. Söldner-Rembold, S. P. Denisov, Sudhir Malik, Ia Iashvili, Helena Malbouisson, D. Chapin, K. M. Chan, Christian Zeitnitz, S. J. De Jong, Iain Alexander Bertram, Michael Rijssenbeek, P. Schieferdecker, H. T. Diehl, T. A. Bolton, J. Lazoflores, Jean-Roch Vlimant, Brajesh C Choudhary, Abdenour Lounis, Y. Pogorelov, A. Jonckheere, P. Haefner, B. Kothari, D. V. Bandurin, Jun Guo, Q. Z. Li, C. De Oliveira Martins, P. N. Ratoff, Robert Harrington, A. Boehnlein, H. Greenlee, D. M. Strom, Tiefu Zhao, B. C.K. Casey, A. Mendes, J. N. Butler, P. D. Grannis, Michael Mulhearn, A. Lobodenko, B. Davies, Heriberto Castilla-Valdez, V. N. Evdokimov, J. Ellison, I. Hall, M. Ahsan, D. Wicke, Ulrike Blumenschein, A. Bross, J. Steele, M. Sosebee, Christophe Royon, Jeroen Hegeman, Sa. Jain, S. Fuess, D. A. Stoyanova, S. Kappler, N. Oshima, Daniel Bloch, M. Das, P. L.M. Podesta-Lerma, Daria Zieminska, R. D. Schamberger, A. A. Shchukin, T. Kurca, J. A. Parsons, Frank Fiedler, Raimund Ströhmer, Serban Protopopescu, P. M. Tuts, Maksym Titov, Marc Weber, Jean-Laurent Agram, Freya Blekman, L. Lobo, Sharon Hagopian, Lorenzo Feligioni, E. Kajfasz, V. Simak, P. Padley, R. F. Rodrigues, S. J. Park, Andy Haas, A. K.A. Maciel, L. Berntzon, Brad Abbott, C. Ay, A. Sanchez-Hernandez, Pierre Petroff, T. Gadfort, V. Zutshi, R. Hooper, H. D. Wahl, Mitchell Wayne, F. Lehner, K. W. Merritt, J. F. Bartlett, A. V. Ferapontov, Michael Begel, P. Vint, V. Oguri, A. Koubarovsky, A. V. Popov, H. Schellman, J. M. Kohli, Andrew Brandt, P. Banerjee, Robert Kehoe, Stefan Grünendahl, P. Verdier, M. Agelou, Andrew Askew, Zhengguo Zhao, Brigitte Vachon, D. Shpakov, J. Hays, Kirti Ranjan, H.E. Miettinen, Carsten Hensel, R. Piegaia, Gustaaf Brooijmans, D. Brown, A. M. Magnan, M. Yan, Gregorio Bernardi, D. Denisov, Mossadek Talby, F. Badaud, J. Warchol, S. Burke, B. Gómez, Eduardo De Moraes Gregores, Shashikant Dugad, G. A. Davis, Boris Tuchming, A. Evdokimov, Luiz Mundim, E. Galyaev, Limin Wang, Marc-Andre Pleier, M. Petteni, J. M. Kalk, J. M. Heinmiller, Hal Evans, Thomas Ferbel, A. Jenkins, T. Yasuda, Wendy Taylor, Lars Sonnenschein, Roger Moore, P. Skubic, V. Siccardi, A. Magerkurth, A. Zatserklyaniy, B. S. Acharya, Y. A. Yatsunenko, Viatcheslav Stolin, J. Molina, Carlos Avila, S. Sumowidagdo, Sabine Crépé-Renaudin, A. C.S. Assis Jesus, Guennadi Borissov, M. C. Cousinou, W. C. Fisher, Neeti Parashar, S. Fu, G. Hesketh, P. J. Van Den Berg, Jessica Levêque, K. Bos, M. Zielinski, Marc Besancon, J. Temple, Michael A. Strauss, P. Lebrun, A. Kryemadhi, O. Boeriu, Shuichi Kunori, D. K. Cho, A. Stone, T. Scanlon, B. Tiller, S. Kermiche, Suman Bala Beri, S. W. Youn, E. Von Toerne, V. Buescher, P. Demine, Vivian O'Dell, A. Juste, Todd Adams, U. Bassler, D. Coppage, S. Robinson, D. Edmunds, Regina Demina, W. D. Shephard, G. Grenier, R. McCroskey, Andre Sznajder, N. A. Naumann, Yuri Gershtein, Emmanuelle Perez, S. Reucroft, D. Käfer, A. Bellavance, T. Moulik, Reinhard Schwienhorst, Emanuela Barberis, Kazunori Hanagaki, Dongliang Zhang, Ashok Kumar, F. Charles, Tulika Bose, Alberto Santoro, J. G.R. Lima, Michael Martens, M. Ford, S. N. Fatakia, V. M. Podstavkov, M. Fortner, B. Clement, W. M. Lee, Ph Gris, P. Houben, P. Rubinov, B. G. Pope, H. E. Fisk, Calvin A. Johnson, S. Calvet, Aran Garcia-Bellido, Elizaveta Shabalina, Timothy Andeen, Vipin Bhatnagar, E. De La Cruz-Burelo, M. P. Sanders, R. Partridge, Christian Autermann, J. M. Hauptman, Kenneth Bloom, V. L. Malyshev, H. S. Mao, Cecilia Elena Gerber, T. Toole, S. Lager, S. Uvarov, Ivor Fleck, G. Ginther, B. Quinn, Makoto Tomoto, C. Schwanenberger, Alice Bean, N. Oliveira, Maria Elena Pol, Jianming Qian, J. Gardner, J. Kotcher, S. Anderson, Harald Fox, M. Vaupel, Y. D. Mutaf, I. A. Vasilyev, P. M. Perea, M. Doidge, P. Mättig, R. Illingworth, A. Leflat, H. Kim, Philip Baringer, S. Banerjee, L. S. Vertogradov, Y. Arnoud, W. E. Cooper, Yann Coadou, Mikko Voutilainen, Arnaud Duperrin, V. M. Korablev, Nikos Varelas, Jong-Sung Yu, G. Obrant, Bing Zhou, Luis Mendoza, R. K. Shivpuri, Shabnam Jabeen, M. Merkin, Raymond Brock, Boaz Klima, I. Katsanos, R. Beuselinck, D. R. Claes, Gavin Davies, Julia S. Meyer, Y. Scheglov, Kaushik De, I. Blackler, Jan Stark, Henry Lubatti, and J. Cammin
Subjects: Physics, Nuclear and High Energy Physics, Gluino, Particle physics, 010308 nuclear & particles physics, Supergravity, High Energy Physics::Phenomenology, Tevatron, 7. Clean energy, 01 natural sciences, Lower limit, law.invention, Nuclear physics, Transverse plane, law, 0103 physical sciences, High Energy Physics::Experiment, Fermilab, 010306 general physics, Collider, Energy (signal processing)
Abstract: The results of a search for squarks and gluinos using data from p p ¯ collisions recorded at a center-of-mass energy of 1.96 TeV by the DO detector at the Fermilab Tevatron Collider are reported. The topologies analyzed consist of acoplanar-jet and multijet events with large missing transverse energy. No evidence for the production of squarks or gluinos was found in a data sample of 310 pb−1. Lower limits of 325 and 241 GeV were derived at the 95% C.L. on the squark and gluino masses, respectively, within the framework of minimal supergravity with tan β = 3 , A 0 = 0 , and μ 0 .
Published: 2006

274. Search for pair production of second generation scalar leptoquarks in pp¯ collisions at s=1.96 TeV

Author: V. M. Abazov, Christophe Royon, V. Shary, H. D. Wahl, D. Bauer, P. Verdier, V. V. Tokmenin, C. Schwanenberger, T. Christiansen, Iain Alexander Bertram, V. Buescher, A. Evdokimov, M. Petteni, E. Galyaev, Michael Rijssenbeek, D. V. Bandurin, H. A. Neal, F. Villeneuve-Seguier, D. Meder, J. T. Linnemann, K. Yip, N. Xuan, J. M. Kalk, Kristian Harder, V. N. Evdokimov, I. Hall, A. Chandra, R. Unalan, L. Stutte, Gregory J Pawloski, U. Bassler, Wendy Taylor, A.S. Dyshkant, Roger Moore, T. Yasuda, V. Siccardi, A. Magerkurth, A. Zatserklyaniy, T. Toole, B. S. Acharya, K. J. Rani, A. Alton, S. Lager, S. Chakrabarti, Peter Love, Jiri Kvita, A. Jenkins, D. Cutts, Wagner Carvalho, Armen Vartapetian, Thomas Trefzger, Emily Nurse, Elizabeth Gallas, S. Robinson, D. Edmunds, W. D. Shephard, R. McCroskey, Andre Sznajder, Robert Hirosky, S. Uvarov, Regina Demina, Ivor Fleck, H. Dong, Christos Leonidopoulos, A. Leflat, G. Obrant, Yuri Gershtein, Emmanuelle Perez, B. Quinn, Emanuela Barberis, P. Skubic, I. Ripp-Baudot, A. M. Kalinin, Dmitri Tsybychev, R. L. McCarthy, A. Yurkewicz, Makoto Tomoto, J. Womersley, D. A. Stoyanova, Alice Bean, D. Buchholz, Sascha Caron, G. D. Alexeev, A. Meyer, T. Moulik, C. Jarvis, M. Lynker, X. F. Song, Reinhard Schwienhorst, Dorothee Schaile, M. Hohlfeld, L. Bagby, Kazunori Hanagaki, Dongliang Zhang, Cris W. Barnes, Adam L. Lyon, P. K. Mal, V. I. Rud, S. Söldner-Rembold, Flera Rizatdinova, N. Oliveira, S. E.K. Mattingly, P. Tamburello, Anna Goussiou, Greg Landsberg, M. Wobisch, A. Pompoš, Mark Raymond Adams, D. Karmanov, Jovan Mitrevski, Ashok Kumar, Maria Elena Pol, Alberto Santoro, J. G.R. Lima, F. Charles, M. Das, F. Lehner, H. Kim, Philip Baringer, V. Lesne, Michael A. Strauss, G. Gutierrez, Gilvan Alves, Nikola Makovec, M. Strovink, Sudhir Malik, Ia Iashvili, B. Tiller, S. W. Youn, E. Von Toerne, P. Demine, M. H. Kirby, N. Gollub, G. Alkhazov, S. Jabeen, M. Merkin, K. M. Chan, Christian Zeitnitz, Jean-Roch Vlimant, Brajesh C Choudhary, W. M. Lee, J. Gardner, M. Kopal, S. Banerjee, P. Lebrun, Pedrame Bargassa, Tulika Bose, O. Boeriu, P. Rubinov, J. M. Hauptman, J. Dyer, F. Badaud, Ashok Das, Suyong Choi, D. Coppage, M. Anastasoaie, Paul Telford, Avto Kharchilava, Arnulf Quadt, P. Renkel, Elemer Nagy, J. Kotcher, S. Anderson, Michael Begel, Karl Jakobs, J. A. Benitez, Eduardo De Moraes Gregores, D. K. Cho, A. Stone, Marcel Vreeswijk, Tobias Golling, T. Scanlon, Cecilia Elena Gerber, Harald Fox, S. Lammers, S. Kermiche, B. Davies, S. Krzywdzinski, Alexander Khanov, Graham Wilson, H. da Motta, Suman Bala Beri, Gregory R Snow, K. Soustruznik, G. Grenier, N. A. Naumann, N. J. Buchanan, D. Wicke, G. Ginther, Raymond Brock, L. Lobo, A. M. Magnan, Boaz Klima, M. Vaupel, Michael Martens, D. Gillberg, Vivian O'Dell, F. Chevallier, B. Spurlock, A. S. Ito, A. Melnitchouk, Zeno Dixon Greenwood, M. Ford, R. Van Kooten, Heriberto Castilla-Valdez, A. Juste, Y. D. Mutaf, I. A. Vasilyev, P. M. Perea, Vipin Bhatnagar, M. D. Corcoran, Todd Adams, E. De La Cruz-Burelo, Pushpalatha C Bhat, C. Noeding, Jianming Qian, Lorenzo Feligioni, Reiner Hauser, S. N. Fatakia, R. Partridge, L. Han, V. Hynek, P. Lewis, J. Snow, V. M. Podstavkov, Sharon Hagopian, I. Katsanos, R. Beuselinck, Christian Schmitt, S. Nelson, M. H.G. Souza, Christophe Clement, Sung Keun Park, A. Zieminski, L. Berntzon, Christian Autermann, S. Reucroft, D. Käfer, A. Bellavance, P. Mättig, R. Illingworth, B. G. Pope, Cristina Galea, A. K.A. Maciel, W. M. Van Leeuwen, M. Fortner, B. Clement, M. C. Cousinou, V. V. Lipaev, V. L. Malyshev, F. Borcherding, G. A. Davis, Boris Tuchming, Luiz Mundim, Limin Wang, Marc-Andre Pleier, R. Gelhaus, M. Doidge, H. Greenlee, T. H. Burnett, B. Hoeneisen, Lee Sawyer, H. S. Mao, Emmanuel Busato, D. M. Strom, B. C.K. Casey, M. Ćwiok, Calvin A. Johnson, S. Calvet, Rupinder Kaur, Bradley Cox, Julia S. Meyer, Y. Hu, Ph Gris, P. Houben, S. Fu, Elizaveta Shabalina, M. Cooke, Nikos Varelas, G. Sajot, W. L. Prado Da Silva, R. Piegaia, Bing Zhou, Luis Mendoza, R. K. Shivpuri, A. Bross, A. Kryemadhi, Timothy Andeen, Tae Jeong Kim, P.F. Ermolov, D. A. Wijngaarden, M. A. Strang, L. S. Vertogradov, R. A. Sidwell, G. Hesketh, R. Otec, Shuichi Kunori, S. Greder, H. E. Fisk, T. Edwards, Serban Protopopescu, M. S. Anzelc, P. J. Van Den Berg, P. Banerjee, Y. Arnoud, Sergey Burdin, M. Eads, D. R. Claes, Gavin Davies, Jessica Levêque, K. Bos, Marc Besancon, J. Temple, S. P. Denisov, Marvin Johnson, W. E. Cooper, S. Doulas, Yann Coadou, Ariel Schwartzman, C. De Oliveira Martins, P. N. Ratoff, Sarah Catherine Eno, Horst Severini, Ulrich Heintz, P. M. Tuts, Maksym Titov, A. Sanchez-Hernandez, V. Zutshi, P. Haefner, Andy Haas, A. V. Kozelov, Mikko Voutilainen, Lev Uvarov, Y. Scheglov, Aran Garcia-Bellido, Kaushik De, S.A. Kahn, Arnaud Duperrin, V. M. Korablev, J. P. Konrath, M. Demarteau, Alexey Ferapontov, Junjie Zhu, M. Abolins, Richard B. Lipton, M. Wetstein, A. Baden, Tiefu Zhao, G. C. Blazey, Y. Yen, D. Chakraborty, Jong-Sung Yu, Kevin Black, M. P. Sanders, I. Blackler, N. K. Mondal, P. Schieferdecker, Jeroen Hegeman, H. T. Diehl, T. A. Bolton, Ulrike Blumenschein, Y. Pogorelov, P. L.M. Podesta-Lerma, I. Torchiani, R. Yamada, A. Boehnlein, Andrew Askew, Zhengguo Zhao, Brigitte Vachon, D. Shpakov, Carmen García, Don Lincoln, Erich Varnes, J. Kasper, Frank Filthaut, C. Biscarat, J. Monk, M. Diesburg, Gregorio Bernardi, D. Denisov, P. A. Rapidis, Jean-Francois Grivaz, J. Ellison, S. H. Ahn, M. Ahsan, Jan Stark, Sa. Jain, S. Fuess, Jean-Laurent Agram, T. Kurca, Henry Lubatti, P. de Jong, M. Arov, Marc Weber, P. Jonsson, Andrew White, Abdenour Lounis, Thomas Hebbeker, D. Khatidze, M. Mulders, J. Cammin, M. Michaut, Brad Abbott, C. Ay, Pierre Petroff, M. Buehler, A. Jonckheere, T. Nunnemann, B. Baldin, A. Lobodenko, K. W. Merritt, Robert Harrington, J. M. Heinmiller, J. F. Bartlett, Jing Li, A. Mendes, Robert Kehoe, M. Agelou, Andrei Nomerotski, M. Yan, S. Burke, L. Duflot, John Hobbs, Mansoora Shamim, N. Oshima, Daniel Bloch, Daria Zieminska, R. D. Schamberger, J. Barreto, Hal Evans, B. Åsman, Thomas Ferbel, Lars Sonnenschein, T. R. Wyatt, A. P. Heinson, Andre Sopczak, B. Andrieu, Elliott Cheu, Victor Daniel Elvira, G. S. Muanza, R. E. Hall, Frederic Deliot, Christopher George Tully, Y. M. Kharzheev, Patrick Slattery, G. J. Otero y Garzón, L. Christofek, Helena Malbouisson, D. Chapin, J. N. Butler, P. D. Grannis, J. Steele, A. C.S. Assis Jesus, Guennadi Borissov, W. C. Fisher, M. Zielinski, Viatcheslav Stolin, J. Molina, Carlos Avila, S. Sumowidagdo, Sabine Crépé-Renaudin, H. Weerts, M. Binder, Lev Dudko, M. Sosebee, Hwi Dong Yoo, S. Sengupta, Freya Blekman, Andrew Brandt, Kirti Ranjan, H.E. Miettinen, Jonas Strandberg, N. Parua, Carsten Hensel, Marco Verzocchi, C. Magass, Dugan O'Neil, E. G. Zverev, Raimund Ströhmer, A. Patwa, Mark Owen, Denis Gelé, N. M. Cason, V. Simak, Marcia Begalli, T. Kuhl, N. Parashar, P. Padley, R. F. Rodrigues, Norbert Wermes, Meenakshi Narain, Sherry Towers, J. Haley, J. D. Degenhardt, M. Jaffré, J. Lazoflores, Mitchell Wayne, H. Schellman, J. M. Kohli, Stefan Grünendahl, D. Brown, Alexander Kupco, Mossadek Talby, B. Gómez, Shashikant Dugad, Randy Ruchti, Sergio F Novaes, Yurii Maravin, Vladimir Gavrilov, K. Gounder, J. R. Kalk, Gordon Watts, O. Atramentov, V. Sirotenko, A. C. Le Bihan, Md. Naimuddin, Stephen Wimpenny, A. S. Turcot, Phillip Gutierrez, Martin Grunewald, V. White, Milos Lokajicek, Darien Wood, Nicholas John Hadley, C. P. Buszello, S. Blessing, G. Savage, Scott Snyder, Juan Estrada, Jun Guo, Q. Z. Li, J. A. Parsons, R. Bernhard, R. J. Madaras, S. Yacoob, George Alverson, D. Hedin, S. Kesisoglou, V. A. Bezzubov, J. P. Negret, R. P. Smith, Sophie Trincaz-Duvoid, J. Kozminski, Michael Hildreth, D. Kau, K. Stevenson, S. Uzunyan, Y. A. Yatsunenko, Harrison Prosper, Y. Xie, Amnon Harel, S. Desai, S. J. Hong, Johannes Elmsheuser, P. Neustroev, R. Jesik, K. A. Johns, T. Gadfort, R. Hooper, V. Oguri, A. Koubarovsky, A. V. Popov, J. Hays, Gustaaf Brooijmans, J. Warchol, S. J. De Jong, B. Kothari, A. A. Shchukin, Frank Fiedler, and E. Kajfasz
Subjects: Quark, Physics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, Branching fraction, Scalar (mathematics), 01 natural sciences, Nuclear physics, Pair production, 0103 physical sciences, Leptoquark, 010306 general physics, Lepton, Boson
Abstract: We report on a search for the pair production of second generation scalar leptoquarks (LQ_2) in ppbar collisions at the center-of-mass energy sqrt(s) = 1.96 TeV, using data corresponding to an integrated luminosity of 294 +- 19 pb^-1 recorded with the D0 detector. No evidence for a leptoquark signal in the LQ_2 LQ_2 -> muq muq channel has been observed, and upper bounds on the product of cross section times branching fraction were set. This yields lower mass limits of m(LQ_2) > 247 GeV for beta = Br(LQ_2->muq) = 1 and m(LQ_2) > 182 GeV for beta = 1/2. Combining these limits with previous D0 results, the lower limits on the mass of a second generation scalar leptoquark are m(LQ_2) > 251 GeV and m(LQ_2) > 204 GeV for beta = 1 and beta = 1/2, respectively.
Published: 2006

275. Buchbesprechungen

Author: Christian Stary, Thomas Deelmann, F. Lehner, Thomas Wagner, Peter Mertens, Lars Schwarze, Peter Neckel, and Rainer Bischoff
Subjects: Information Systems
Published: 2006

276. The LHCb Silicon Tracker Project

Author: H. Voss, J. Blouw, Cristina Lois, S. Löchner, Minh Tâm Tran, Roland Bernet, Werner Hofmann, D. Baumeister, A. Vollhardt, F. Lehner, R. Frei, M. Agari, P. Vasquez, O. Steinkamp, K. T. Knöpfle, U. Straumann, J. Gassner, A. Bay, Valery Pugatch, M. Siegler, Y. Ermoline, C. Bauer, D. Volyanskyy, M. Needham, D. Esperante, R.P. Bernhard, Bernardo Adeva, B. Carron, S. Jiminez-Otero, M. Schmelling, and S. Köstner
Subjects: Nuclear and High Energy Physics, Web of science, Silicon, chemistry, Computer science, business.industry, Embedded system, chemistry.chemical_element, business, Atomic and Molecular Physics, and Optics, Computer hardware
Abstract: Two silicon strip detectors, the Trigger Tracker(TT) and the Inner Tracker(IT) will be constructed for the LHCb experiment. Transverse momentum information extracted from the TT will be used in the Level 1 trigger. The IT is part of the main tracking system behind the magnet. Both silicon detectors will be read out using a custom-developed chip by the ASIC lab in Heidelberg. The signal-over-noise behavior and performance of various geometrical designs of the silicon sensors, in conjunction with the Beetle read-out chip, have been extensively studied in test beam experiments. Results from those experiments are presented, and have been used in the final choice of sensor geometry.
Published: 2006

277. Measurement of the tt¯ production cross section in pp¯ collisions at s=1.96 TeV in dilepton final states

Author: H. E. Fisk, L. S. Vertogradov, T. Toole, Aran Garcia-Bellido, J. P. Konrath, B. Davies, Y. Arnoud, A. Leflat, S. Lager, S. Uvarov, K. Gounder, J. R. Kalk, Graham Wilson, P. K. Mal, V. M. Abazov, W. E. Cooper, V. Shary, Ivor Fleck, M. P. Sanders, Yann Coadou, H. da Motta, D. Gillberg, J. Torborg, B. Quinn, D. Chakraborty, A. S. Ito, A. Melnitchouk, O. Atramentov, Sharon Hagopian, Makoto Tomoto, C. Magass, Dugan O'Neil, E. G. Zverev, Don Lincoln, Erich Varnes, A. Patwa, Alice Bean, Iain Alexander Bertram, J. M. Hauptman, Cecilia Elena Gerber, G. Ginther, S. Banerjee, Jianming Qian, V. Hynek, Robert Hirosky, Michael Rijssenbeek, M. Doidge, P. W. Balm, Denis Gelé, N. M. Cason, Arnaud Duperrin, V. M. Korablev, N. Oliveira, G. Savage, V. V. Lipaev, Marcia Begalli, A. M. Kalinin, K. W. Merritt, J. F. Bartlett, H. Kim, Philip Baringer, S. Jabeen, Robert Kehoe, Norbert Wermes, Meenakshi Narain, Jong-Sung Yu, Sherry Towers, D. Wicke, M. Agelou, J. Fast, A. M. Magnan, M. Yan, J. D. Degenhardt, V. N. Evdokimov, I. Hall, A. Chandra, S. Burke, J. Lazoflores, M. Sosebee, Maria Elena Pol, B. G. Pope, J. Gardner, Jing Li, G. Alkhazov, Freya Blekman, Adam L. Lyon, Markus Klute, J. Kotcher, S. Anderson, S. E.K. Mattingly, Harald Fox, T. Vu Anh, Elizaveta Shabalina, Michael A. Strauss, Juan Estrada, Jovan Mitrevski, G. Gutierrez, Gilvan Alves, Nikola Makovec, M. Vaupel, M. Zdrazil, Y. D. Mutaf, D. A. Stoyanova, I. A. Vasilyev, P. M. Perea, Emmanuel Busato, Armen Vartapetian, U. Bassler, S. Robinson, Regina Demina, T. Moulik, Alberto Santoro, J. G.R. Lima, P. Rubinov, M. Abolins, L. Duflot, B. Åsman, R. Piegaia, L. Groer, Karl Jakobs, Kevin Black, M. Anastasoaie, N. K. Mondal, P. Schieferdecker, Andrew Brandt, P. Lebrun, W. M. Van Leeuwen, Arnulf Quadt, A. A. Mayorov, O. Boeriu, Y. Kulik, Kirti Ranjan, H.E. Miettinen, Vivek Jain, Q. Xu, Paul Telford, Carsten Hensel, Timothy Andeen, R. L. McCarthy, Christian Schmitt, S. Nelson, M. H.G. Souza, R. Gelhaus, Elemer Nagy, D. K. Cho, A. Stone, M. Das, A. P. Heinson, G. S. Muanza, A. Yurkewicz, R. E. Hall, Tae Jeong Kim, Tobias Golling, T. Scanlon, S. Kermiche, Alexander Khanov, Rupinder Kaur, Daniel Whiteson, Bradley Cox, V. I. Rud, S. Söldner-Rembold, P. Lewis, J. Snow, Christophe Clement, Nikos Varelas, Bing Zhou, Vipin Bhatnagar, Marvin Johnson, E. De La Cruz-Burelo, A. Kryemadhi, Suman Bala Beri, A. V. Kozelov, Shuichi Kunori, L. Lobo, Vivian O'Dell, N. Lahrichi, R. Partridge, X. Zhang, Lorenzo Feligioni, Emanuela Barberis, L. Christofek, M. Kopal, Christian Autermann, A. Juste, Michael Begel, Eduardo De Moraes Gregores, Kazunori Hanagaki, Dongliang Zhang, Todd Adams, Helena Malbouisson, D. Chapin, V. L. Malyshev, M. Merkin, H. S. Mao, G. A. Davis, Raimund Ströhmer, V. Simak, S. Chakrabarti, Peter Love, Boris Tuchming, Luiz Mundim, Abdenour Lounis, Raymond Brock, Boaz Klima, Cris W. Barnes, P. Padley, R. F. Rodrigues, J. N. Butler, P. D. Grannis, R. Beuselinck, Robert Harrington, Limin Wang, Mitchell Wayne, S. Krzywdzinski, H. Schellman, J. M. Kohli, A. Mendes, R. J. Madaras, Marc-Andre Pleier, J. Steele, Stefan Grünendahl, Julia S. Meyer, F. Lehner, F. Villeneuve-Seguier, Mossadek Talby, B. Gómez, S. Yacoob, H. Greenlee, D. M. Strom, B. C.K. Casey, Shashikant Dugad, T. H. Burnett, Heriberto Castilla-Valdez, Alexandre Zabi, A. Bross, A. Cothenet, K. J. Rani, A. Alton, Serban Protopopescu, George Alverson, Tiefu Zhao, Ashok Kumar, S. W. Youn, E. Von Toerne, P. Demine, Andy Haas, K. Genser, D. Hedin, A. Sanchez-Hernandez, Ulrike Blumenschein, S. Kesisoglou, Q. Z. Li, P. L.M. Podesta-Lerma, D. Coppage, K. M. Chan, Christian Zeitnitz, V. Zutshi, F. Charles, Ulrich Heintz, J. A. Parsons, Jean-Laurent Agram, N. A. Naumann, M. Cooke, W. L. Prado Da Silva, Frank Filthaut, Tulika Bose, S. Reucroft, Brad Abbott, Andrew Askew, Zhengguo Zhao, D. Käfer, A. Bellavance, Ariel Schwartzman, M. Diesburg, M. Verzocchi, Pierre Petroff, Brigitte Vachon, D. Shpakov, P.F. Ermolov, Stephen Wimpenny, Martin Grunewald, J. Kasper, V. White, Milos Lokajicek, D. Edmunds, Andrew White, M. Michaut, Darien Wood, Nicholas John Hadley, W. D. Shephard, C. P. Buszello, Alexey Ferapontov, S. Blessing, R. McCroskey, Andre Sznajder, Scott Snyder, V. A. Bezzubov, Karel Smolek, H. Dong, Andrei Nomerotski, J. P. Negret, Yuri Gershtein, D. Buchholz, Emmanuelle Perez, R. K. Shivpuri, John Hobbs, J. Barreto, P. Tamburello, D. R. Claes, Gavin Davies, Anna Goussiou, S. Doulas, T. Nunnemann, B. Baldin, J. Dyer, R. P. Smith, Gregory R Snow, Sophie Trincaz-Duvoid, Kaushik De, Sung Keun Park, Mansoora Shamim, Reinhard Schwienhorst, J. Kozminski, M. C. Cousinou, I. Blackler, R. Van Kooten, M. D. Corcoran, Jan Stark, W. M. Lee, A. Kharchilava, L. Lueking, Henry Lubatti, L. Han, S. Fu, Andre Sopczak, J. Cammin, B. Andrieu, A. Zieminski, Michael Hildreth, R. Bernhard, D. A. Wijngaarden, M. Buehler, D. Kau, Elliott Cheu, Victor Daniel Elvira, G. Hesketh, A. Harel, P. J. Van Den Berg, Jessica Levêque, K. Bos, Marc Besancon, J. Temple, J. Huang, R. A. Sidwell, Michael Martens, N. R. Stanton, K. Stevenson, S. Uzunyan, Y. A. Yatsunenko, C. Han, S. N. Fatakia, V. M. Podstavkov, M. Fortner, B. Clement, L. Phaf, Y. Hu, Ph Gris, Frederic Deliot, C. De Oliveira Martins, Christopher George Tully, P. Houben, P. N. Ratoff, Y. M. Kharzheev, Patrick Slattery, G. J. Otero y Garzón, Harrison Prosper, S. Desai, P. M. Tuts, V. Buescher, P. Mättig, R. Illingworth, S. J. Hong, N. Gollub, Suyong Choi, Gregorio Bernardi, D. Denisov, J. M. Heinmiller, Hal Evans, Thomas Ferbel, Lars Sonnenschein, A. C.S. Assis Jesus, Guennadi Borissov, W. C. Fisher, Neeti Parashar, M. Zielinski, Thomas Trefzger, G. D. Alexeev, Flera Rizatdinova, R. Zitoun, H. T. Diehl, T. A. Bolton, Y. Pogorelov, C. Biscarat, P. A. Rapidis, A. Jonckheere, S. Dean, Stephan Linn, A. Lobodenko, S. N. Gurzhiev, N. Oshima, A. Boehnlein, J. Ellison, A. K.A. Maciel, M. Ahsan, Sa. Jain, S. Fuess, T. Kurca, Marc Weber, I. Ripp-Baudot, Daniel Bloch, Marcel Vreeswijk, B. Spurlock, Zeno Dixon Greenwood, Marumi Kado, Daria Zieminska, Cristina Galea, T. Edwards, R. D. Schamberger, T. R. Wyatt, Pushpalatha C Bhat, Reiner Hauser, B. Hoeneisen, Lee Sawyer, Viatcheslav Stolin, J. Molina, S.A. Kahn, Lev Uvarov, Carlos Avila, S. Sumowidagdo, M. Demarteau, Carmen García, Sabine Crépé-Renaudin, Sergey Burdin, S. P. Denisov, Sergio F Novaes, Yurii Maravin, Vladimir Gavrilov, Gordon Watts, V. Sirotenko, A. C. Le Bihan, O. V. Eroshin, A. S. Turcot, Phillip Gutierrez, T. Christiansen, H. A. Neal, Jonas Strandberg, N. Parua, D. Meder, J. T. Linnemann, K. Yip, N. Xuan, M. Eads, M. Jaffré, L. Stutte, Gregory J Pawloski, A.S. Dyshkant, Jiri Kvita, S. J. De Jong, B. Kothari, Christos Leonidopoulos, Alexander Kupco, J. Womersley, J. Wittlin, M. Wobisch, A. Pompoš, Stephanie Beauceron, D. Karmanov, Sudhir Malik, Ia Iashvili, Jean-Roch Vlimant, Brajesh C Choudhary, A. A. Shchukin, Randy Ruchti, Frank Fiedler, E. Kajfasz, F. Borcherding, G. Sajot, S. Greder, Emily Nurse, Elizabeth Gallas, Sarah Catherine Eno, Horst Severini, Johannes Elmsheuser, P. Neustroev, Junjie Zhu, R. Jesik, K. A. Johns, P. Verdier, Richard B. Lipton, Kristian Harder, A. Evdokimov, T. Gadfort, R. Hooper, M. A. Strang, M. Petteni, D. Cutts, V. Oguri, A. Koubarovsky, J. Hays, Gustaaf Brooijmans, Wagner Carvalho, J. Warchol, Sascha Caron, A. Jenkins, Greg Landsberg, P. Skubic, M. Strovink, H. Weerts, M. Binder, Pedrame Bargassa, A. Meyer, Lev Dudko, K. Soustruznik, C. Noeding, N. J. Buchanan, Hwi Dong Yoo, S. Sengupta, A. Baden, G. C. Blazey, Y. Yen, R. Yamada, Jean-Francois Grivaz, S. H. Ahn, P. de Jong, P. Jonsson, Thomas Hebbeker, M. Mulders, Mary Beth Adams, Christophe Royon, H. D. Wahl, D. Bauer, F. Badaud, C. Schwanenberger, E. Galyaev, T. Yasuda, M. Lynker, X. F. Song, Dorothee Schaile, M. Hohlfeld, Wendy Taylor, Roger Moore, A. Magerkurth, A. Zatserklyaniy, and B. S. Acharya
Subjects: Nuclear and High Energy Physics, Particle physics, Top quark, Tevatron, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, 7. Clean energy, Bottom quark, law.invention, Standard Model, Nuclear physics, law, 0103 physical sciences, Fermilab, Nuclear Experiment, 010306 general physics, Collider, Physics, Muon, Luminosity (scattering theory), 010308 nuclear & particles physics, High Energy Physics::Phenomenology, b-tagging, Pair production, Content (measure theory), Production (computer science), High Energy Physics::Experiment, Energy (signal processing), Lepton
Abstract: We present a measurement of the top quark pair ($t\bar{t}$) production cross section ($\sigma_{t\bar{t}}$) in $p\bar{p}$ collisions at $\sqrt{s}=1.96$ TeV using 230 pb$^{-1}$ of data collected by the D0 experiment at the Fermilab Tevatron Collider. We select events with one charged lepton (electron or muon), missing transverse energy, and jets in the final state. We employ lifetime-based b-jet identification techniques to further enhance the $t\bar{t}$ purity of the selected sample. For a top quark mass of 175 GeV, we measure $\sigma_{t\bar{t}}=8.6^{+1.6}_{-1.5}(stat.+syst.)\pm 0.6(lumi.)$ pb, in agreement with the standard model expectation
Published: 2005

278. Search for single top quark production in pp¯ collisions at s=1.96 TeV

Author: P. Lebrun, Karel Smolek, H. Dong, Adam L. Lyon, A. Baden, O. Boeriu, Y. Kulik, Christos Leonidopoulos, D. Buchholz, D. K. Cho, A. Stone, G. C. Blazey, Y. Yen, Christophe Royon, Tobias Golling, T. Scanlon, M. Anastasoaie, S. Kermiche, R. Yamada, Jean-Francois Grivaz, S. H. Ahn, P. de Jong, Arnulf Quadt, P. Tamburello, J. Womersley, C. Biscarat, P. A. Rapidis, Suman Bala Beri, Vivian O'Dell, Elemer Nagy, Anna Goussiou, F. Villeneuve-Seguier, A. Jonckheere, S. Dean, J. M. Hauptman, Cecilia Elena Gerber, M. Sosebee, P. Jonsson, Stephan Linn, A. Lobodenko, J. Wittlin, R. K. Shivpuri, N. Oshima, J. Dyer, Gregory R Snow, Kevin Black, A. Juste, H. D. Wahl, Daniel Bloch, Daria Zieminska, G. Ginther, R. D. Schamberger, Jianming Qian, L. Lobo, Lorenzo Feligioni, N. K. Mondal, P. Schieferdecker, H. T. Diehl, T. A. Bolton, D. Bauer, N. Gollub, W. M. Van Leeuwen, Emily Nurse, Elizabeth Gallas, T. Edwards, L. Duflot, Vipin Bhatnagar, Thomas Hebbeker, M. Mulders, M. Wobisch, A. Pompoš, Lev Uvarov, D. R. Claes, Gavin Davies, S. Doulas, Y. Pogorelov, A. Boehnlein, J. Ellison, A. K.A. Maciel, Sa. Jain, S. Fuess, T. Kurca, Marc Weber, A. Lounis, E. De La Cruz-Burelo, Stephanie Beauceron, D. Karmanov, Michael Martens, C. Schwanenberger, Thomas Trefzger, B. Clément, B. Åsman, K. J. Rani, Freya Blekman, R. Kaur, M. C. Cousinou, N. Lahrichi, A. P. Heinson, R. Partridge, X. Zhang, M. A. Strang, M. Merkin, S. W. Youn, E. Von Toerne, P. Demine, Sung Keun Park, Suyong Choi, T. Vu Anh, E. Galyaev, M. Zdrazil, V. A. Bezzubov, Sudhir Malik, G. S. Muanza, A. Meyer, Kaushik De, M. Doidge, Christian Schmitt, S. Nelson, F. Badaud, G. D. Alexeev, Flera Rizatdinova, Marcel Vreeswijk, B. Spurlock, Zeno Dixon Greenwood, T. Adams, Alexandre Zabi, P. Verdier, M. H.G. Souza, J. P. Negret, Cristina Galea, Andrew Brandt, R. Zitoun, D. Coppage, I. Blackler, Armen Vartapetian, Raymond Brock, Boaz Klima, R. Gelhaus, Christian Autermann, B. G. Pope, R. W. Moore, S. N. Fatakia, A. Evdokimov, V. M. Podstavkov, Ia Iashvili, Jean-Roch Vlimant, Brajesh C Choudhary, R. E. Hall, R. P. Smith, Sophie Trincaz-Duvoid, L. Lueking, T. Yasuda, S. Fu, Johannes Elmsheuser, Kirti Ranjan, H.E. Miettinen, Terry Richard Wyatt, P. Neustroev, F. Borcherding, K. Gounder, J. R. Kalk, M. Petteni, R. Bernhard, D. A. Wijngaarden, O. Atramentov, R. Beuselinck, Tae Jeong Kim, Carsten Hensel, Jan Stark, U. Bassler, G. Alkhazov, Henry Lubatti, M. Fortner, V. L. Malyshev, J. Kozminski, Michael Hildreth, Bradley Cox, Wendy Taylor, Pushpalatha C Bhat, D. Kau, Reiner Hauser, S. Reucroft, P.F. Ermolov, K. M. Chan, Christian Zeitnitz, R. Jesik, H. S. Mao, A. Jenkins, S. Robinson, G. Hesketh, M. Cooke, Regina Demina, R. L. McCarthy, Elizaveta Shabalina, J. Cammin, G. Sajot, N. A. Naumann, K. A. Johns, A. Yurkewicz, B. Hoeneisen, Lee Sawyer, A. Harel, C. Han, D. Chakraborty, K. Stevenson, P. J. Van Den Berg, Jessica Levêque, K. Bos, Marc Besancon, J. Temple, Y. Hu, Ph Gris, A. Magerkurth, P. Skubic, P. Houben, S. Uzunyan, T. Moulik, A. Zatserklyaniy, T. Christiansen, W. L. Prado Da Silva, H. A. Neal, D. Meder, J. T. Linnemann, Don Lincoln, Erich Varnes, Alexey Ferapontov, K. Yip, N. Xuan, Y. A. Yatsunenko, B. S. Acharya, P. W. Balm, C. De Oliveira Martins, P. N. Ratoff, Alberto Santoro, S. Greder, J. G.R. Lima, Sarah Catherine Eno, Horst Severini, M. Ahsan, Marvin Johnson, V. I. Rud, S. Söldner-Rembold, B. Davies, M. Buehler, Harrison Prosper, S.A. Kahn, M. Demarteau, T. Gadfort, Carmen García, Frederic Deliot, P. M. Tuts, G. Savage, Julia S. Meyer, Emanuela Barberis, Kazunori Hanagaki, Dongliang Zhang, Emmanuel Busato, Gregorio Bernardi, A. V. Kozelov, D. Denisov, Junjie Zhu, S. Desai, L. Stutte, Gregory J Pawloski, D. Käfer, A. Bellavance, P. Rubinov, A. C. Le Bihan, C. Magass, M. Kopal, Dugan O'Neil, E. G. Zverev, Ariel Schwartzman, N. R. Stanton, T. Toole, Richard B. Lipton, S. Lager, Robert Hirosky, R. Hooper, S. J. Hong, J. Fast, A.S. Dyshkant, Juan Estrada, T. Andeen, M. Lynker, X. F. Song, J. M. Heinmiller, Hal Evans, Thomas Ferbel, Lars Sonnenschein, A. M. Kalinin, A. Patwa, Denis Gelé, N. M. Cason, Sascha Caron, S. Chakrabarti, Peter Love, L. S. Vertogradov, Jiri Kvita, D. Edmunds, H. E. Fisk, Marcia Begalli, Tiefu Zhao, Dorothee Schaile, Jing Li, V. Oguri, A. Koubarovsky, Ashok Kumar, Graham Wilson, H. da Motta, D. Gillberg, A. S. Ito, A. Melnitchouk, Jovan Mitrevski, M. Hohlfeld, K. Genser, Norbert Wermes, Meenakshi Narain, Sherry Towers, Y. Arnoud, Aran Garcia-Bellido, J. P. Konrath, R. J. Madaras, W. D. Shephard, R. McCroskey, Andre Sznajder, S. Uvarov, M. Strovink, Kristian Harder, D. Cutts, Wagner Carvalho, Greg Landsberg, Pedrame Bargassa, G. Gutierrez, Gilvan Alves, Nikola Makovec, Ivor Fleck, B. Quinn, Nikos Varelas, J. Kasper, J. Hays, Ulrike Blumenschein, Gustaaf Brooijmans, K. Soustruznik, Sharon Hagopian, S. Yacoob, P. K. Mal, W. E. Cooper, Raimund Ströhmer, V. Simak, P. Padley, R. F. Rodrigues, V. Hynek, Bing Zhou, E. E. Boos, J. D. Degenhardt, Yuri Gershtein, Emmanuelle Perez, B. Abbott, L. Groer, Karl Jakobs, Makoto Tomoto, Yann Coadou, Chris P. Barnes, Heriberto Castilla-Valdez, P. L.M. Podesta-Lerma, J. Lazoflores, Mitchell Wayne, S. Anderson, H. Schellman, J. M. Kohli, V. V. Lipaev, H. Weerts, A. Kryemadhi, Stephen Wimpenny, M. Binder, M. P. Sanders, Alice Bean, R. Piegaia, L. Christofek, A. A. Mayorov, George Alverson, M. Adams, Andrew White, Tulika Bose, J. Warchol, M. Michaut, Shuichi Kunori, Stefan Grünendahl, Helena Malbouisson, D. Chapin, Martin Grunewald, V. White, Arnaud Duperrin, V. M. Korablev, D. Hedin, Reinhard Schwienhorst, Milos Lokajicek, Lev Dudko, Jean-Laurent Agram, P. Lewis, S. Kesisoglou, V. M. Abazov, P. Mättig, Viacheslav Bunichev, Mossadek Talby, M. Verzocchi, J. Snow, Jong-Sung Yu, B. Gómez, J. Torborg, C. Noeding, N. Oliveira, R. Illingworth, J. N. Butler, P. D. Grannis, Iain Alexander Bertram, S. J. De Jong, Shashikant Dugad, Michael Rijssenbeek, A. Leflat, J. Steele, Darien Wood, Nicholas John Hadley, C. P. Buszello, Hwi Dong Yoo, S. Sengupta, Maria Elena Pol, B. Kothari, Andrei Nomerotski, D. Wicke, Pierre Petroff, John Hobbs, V. N. Evdokimov, I. Ripp-Baudot, I. Hall, A. Chandra, S. Blessing, A. Cothenet, J. Barreto, Jonas Strandberg, N. Parua, H. Kim, Philip Baringer, S. Jabeen, S. Banerjee, Scott Snyder, R. Van Kooten, A. Sanchez-Hernandez, M. Eads, A. A. Shchukin, Frank Fiedler, V. Zutshi, J. Gardner, M. D. Corcoran, E. Kajfasz, M. Jaffré, Q. Z. Li, L. Han, J. Kotcher, Robert Harrington, A. Zieminski, A. Mendes, Zhengguo Zhao, Brigitte Vachon, Harald Fox, D. Shpakov, J. Huang, Alexander Kupco, A. Alton, F. Charles, C. Clément, T. Nunnemann, B. Baldin, Randy Ruchti, Sergio F Novaes, V. Buescher, M. Vaupel, Y. D. Mutaf, I. A. Vasilyev, P. M. Perea, Yurii Maravin, Vladimir Gavrilov, Gordon Watts, V. Sirotenko, O. V. Eroshin, A. S. Turcot, Phillip Gutierrez, R. A. Sidwell, Mansoora Shamim, A. Askew, W. M. Lee, A. Kharchilava, Andre Sopczak, B. Andrieu, S. E.K. Mattingly, Elliott Cheu, Victor Daniel Elvira, V. V. Shary, Vivek Jain, Q. Xu, Paul Telford, Alexander Khanov, N. J. Buchanan, K. W. Merritt, J. F. Bartlett, Robert Kehoe, M. Agelou, A. M. Magnan, M. Yan, S. Burke, Sergey Burdin, S. P. Denisov, A. C.S. Assis Jesus, Guennadi Borissov, W. C. Fisher, Neeti Parashar, M. Abolins, M. Zielinski, S. N. Gurzhiev, Viatcheslav Stolin, J. Molina, Carlos Avila, S. Sumowidagdo, Sabine Crépé-Renaudin, S. Krzywdzinski, F. Lehner, H. Greenlee, D. M. Strom, B. C.K. Casey, A. Bross, Christopher George Tully, Y. M. Kharzheev, Serban Protopopescu, Patrick Slattery, G. J. Otero y Garzón, J. A. Parsons, T. H. Burnett, Ulrich Heintz, Frank Filthaut, M. Diesburg, Andy Haas, D. A. Stoyanova, M. Das, Michael Begel, Eduardo De Moraes Gregores, G. A. Davis, Boris Tuchming, Luiz Mundim, Limin Wang, Marc-Andre Pleier, and Michael A. Strauss
Subjects: Physics, Quark, Nuclear and High Energy Physics, Top quark, Particle physics, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Electroweak interaction, Tevatron, Particle accelerator, 01 natural sciences, law.invention, Nuclear physics, Pair production, law, 0103 physical sciences, High Energy Physics::Experiment, Fermilab, 010306 general physics, Collider
Abstract: We present a search for electroweak production of single top quarks in the s-channel and t-channel using neural networks for signal-background separation. We have analyzed 230 pb(-1) of data collected with the DO detector at the Fermilab Tevatron Collider at a center-of-mass energy of 1.96 TeV and find no evidence for a single top quark signal. The resulting 95% confidence level upper limits on the single top quark production cross sections are 6.4 pb in the s-channel and 5.0 ph in the t-channel. (c) 2005 Elsevier B.V. All rights reserved.
Published: 2005

279. The LHCb silicon tracker

Author: B. Adeva, M. Agari, C. Bauer, D. Baumeister, A. Bay, R.P. Bernhard, R. Bernet, J. Blouw, B. Carron, Y. Ermoline, D. Esperante, R. Frei, J. Gassner, W. Hofmann, S. Jimenez-Otero, K.T. Knöpfle, S. Köstner, F. Lehner, S. Löchner, C. Lois, M. Needham, V. Pugatch, M. Schmelling, B. Schwingenheuer, M. Siegler, O. Steinkamp, U. Straumann, M.T. Tran, P. Vazquez, A. Vollhardt, D. Volyanskyy, and H. Voss
Subjects: Nuclear and High Energy Physics, Instrumentation
Published: 2005

280. Rapid induction of mammary cancer by repeated subcutaneous injection of the trans-3,4-dihydrodiol of 7,12-dimethylbenz[a]anthracene in the female Sprague–Dawley rat

Author: James W. Flesher, Andreas F. Lehner, and Jamie Horn
Subjects: Cancer Research, medicine.medical_specialty, Time Factors, 9,10-Dimethyl-1,2-benzanthracene, Injections, Subcutaneous, Rats, Sprague-Dawley, chemistry.chemical_compound, Subcutaneous injection, Oral administration, Internal medicine, polycyclic compounds, medicine, Animals, Carcinogen, Anthracene, 7,12-Dimethylbenz[a]anthracene, Mammary Neoplasms, Experimental, Cancer, Sarcoma, medicine.disease, Rats, Leukemia, Endocrinology, Solubility, Oncology, chemistry, Female
Abstract: The oral administration of a single 20mg dose of 7,12-dimethylbenz[a]anthracene regularly and rapidly induces mammary cancer in 50 day-old Sprague-Dawley female rats [Experimental Leukemia and Mammary Cancer, 1979, p. 74]. Several mechanisms by which 7,12-dimethylbenz[a]anthracene induces mammary cancer have been proposed and various derivatives have been implicated as possible proximate or ultimate electrophilic and carcinogenic forms of this hydrocarbon. Here we show that 7,12-dimethylbenz[a]anthracene-trans-3,4-dihydrodiol rapidly induces mammary cancer by repeated subcutaneous injection in a high proportion of female Sprague-Dawley rats without malignancies at the site of injection, whereas its more lipid soluble diacetate derivative induced injection site sarcomas in addition to distal mammary cancers. By contrast, repeated subcutaneous injection of 7,12-dimethylbenz[a]anthracene and its 7-meso-aldehyde derivative induced subcutaneous sarcoma in most, if not all, rats and a few mammary cancers.
Published: 2005

281. Epithelial re-organization and dynamics of progression through mitosis inDrosophilaseparase complex mutants

Author: Christian F. Lehner, Stefan Heidmann, and Rahul Pandey
Subjects: Cohesin complex, Mitosis, Cell Cycle Proteins, Chromatids, Biology, Chromosomes, Epithelium, Endopeptidases, Animals, Drosophila Proteins, Sister chromatids, Metaphase, Separase, Cytokinesis, Anaphase, Centrosome, Cohesin, Cell Biology, Cell biology, Securin, Mutation, Drosophila
Abstract: Separase cleaves a subunit of the cohesin complex and thereby promotes sister chromatid separation during mitotic and meiotic divisions. Drosophila separase associates with regulatory subunits encoded by the pimples and three rows genes. Three rows and Pimples, the Drosophila securin, are required for sister chromatid separation during mitosis. Budding yeast separase provides other functions in addition to cohesin subunit cleavage, which are required for spindle organization and temporal regulation during exit from mitosis. Therefore, using time-lapse imaging in live embryos, we have carefully analyzed progression through mitosis in pimples and three rows mutants. We demonstrate that despite the total failure of sister chromatid separation, exit from mitosis, including a complete cytokinesis, proceeds with only a minor temporal delay in the epidermal cells of these mutants. Interestingly, however, pronounced defects in the epithelial organization develop in the following interphase, indicating that the separase complex is not only important for genetic stability but also and perhaps indirectly for epithelial integrity.
Published: 2005

282. Development of a Method for the Detection and Confirmation of the alpha-2 Agonist Amitraz and Its Major Metabolite in Horse Urine

Author: Andreas F. Lehner, J. Boyles, L. Dirikolu, W. Karpiesiuk, W. E. Woods, Charlie Hughes, F. C. Camargo, Thomas Tobin, Jeffrey M. Bosken, A. Troppmann, and J. D. Harkins
Subjects: Spectrometry, Mass, Electrospray Ionization, Time Factors, Toluidines, Health, Toxicology and Mutagenesis, Electrospray ionization, Metabolite, Amidines, Toxicology, Mass spectrometry, Gas Chromatography-Mass Spectrometry, Analytical Chemistry, chemistry.chemical_compound, Animals, Environmental Chemistry, Selected ion monitoring, Horses, Adrenergic agonist, Derivatization, Amitraz, Detection limit, Chemical Health and Safety, Chromatography, Substance Abuse Detection, chemistry, Female, Adrenergic alpha-Agonists
Abstract: Amitraz (N'-(2,4-dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methyl-methanimidamide) is an alpha-2 adrenergic agonist used in veterinary medicine primarily as a scabicide- or acaricide-type insecticide. As an alpha-2 adrenergic agonist, it also has sedative/tranquilizing properties and is, therefore, listed as an Association of Racing Commissioners International Class 3 Foreign Substance, indicating its potential to influence the outcome of horse races. We identified the principal equine metabolite of amitraz as N-2,4-dimethylphenyl-N'-methylformamidine by electrospray ionization(+)-mass spectrometry and developed a gas chromatographic-mass spectrometric (GC-MS) method for its detection, quantitation, and confirmation in performance horse regulation. The GC-MS method involves derivatization with t-butyldimethylsilyl groups; selected ion monitoring (SIM) of m/z 205 (quantifier ion), 278, 261, and 219 (qualifier ions); and elaboration of a calibration curve based on ion area ratios involving simultaneous SIM acquisition of an internal standard m/z 208 quantifier ion based on an in-house synthesized d 6 deuterated metabolite. The limit of detection of the method is approximately 5 ng/mL in urine and is sufficiently sensitive to detect the peak urinary metabolite at 1 h post dose, following administration of amitraz at a 75-mg/horse intraveneous dose.
Published: 2004

283. Chromatographic Detection of Trimetoquinol (Inolin�) and its Major Urinary Metabolites in the Horse: A Preliminary Report

Author: W. E. Woods, Andreas F. Lehner, W. Karpiesiuk, J. Boyles, Charlie Hughes, J. D. Harkins, Thomas Tobin, and F. C. Camargo
Subjects: Chromatography, Chemistry, Tetrahydroisoquinoline, Metabolite, Organic Chemistry, Clinical Biochemistry, Selected reaction monitoring, Urine, Biochemistry, High-performance liquid chromatography, Analytical Chemistry, chemistry.chemical_compound, Solid phase extraction, Glucuronide, Quantitative analysis (chemistry)
Abstract: Trimetoquinol (TMQ) (1-(3’,4’,5’-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, m.w. 345) is the prototype tetrahydroisoquinoline pharmaceutical. TMQ is marketed as a bronchodilator in human medicine; in horse racing, TMQ is listed as an Association of Racing Commissioners International (ARCI) class 3 foreign substance. As such, TMQ is considered to have the potential to affect racing performance in horses, and a validated qualitative confirmatory method is required to regulate its use in racing. We selected 8 μg kg−1 of TMQ IV as a safe and effective dose for studies on its metabolism and analytical detection in horses. We developed a solid phase extraction method for recovery of TMQ and its metabolites from equine urine, identified suitable high performance liquid chromatographic conditions for these substances and our internal standard, papaverine, and developed a highly sensitive ESI(+)-LC-MS-MS method (estimated LOD, 100 pg mL−1) for TMQ and its major metabolites in equine urine. Multiple Reaction Monitoring (MRM) analysis of unhydrolyzed post-administration urine showed small amounts of unchanged TMQ, along with glucuronide, methylated, and sulfated metabolites, with glucuronide metabolites predominating. Following glucuronidase hydrolysis, recovered parent TMQ peaked at relatively high concentrations (>300 ng mL−1) within 1 h of administration and thereafter declined. The methylated metabolites of TMQ peaked later and at comparable total concentrations, and thereafter declined more slowly. These data suggest that glucuronide hydrolysis of post-administration urine samples will allow recovery of readily identifiable quantities of parent TMQ. These findings, combined with the highly sensitive LC-MS-MS detection of parent TMQ described herein suggest that glucuronide hydrolysis of post-administration urine, followed by LC-MS-MS or other analysis, will allow effective regulatory control of this agent in racing horses.
Published: 2004

284. Formation of radical cations in a model for the metabolism of aromatic hydrocarbons

Author: Jamie Horn, James W. Flesher, and Andreas F. Lehner
Subjects: Anthracene, Free Radicals, Biophysics, Electrons, Cell Biology, Photochemistry, Hydrocarbons, Aromatic, Biochemistry, Medicinal chemistry, Electron Transport, Structure-Activity Relationship, chemistry.chemical_compound, Radical ion, chemistry, Biotransformation, Cations, Electrophile, Carcinogens, Pyrene, Polycyclic Hydrocarbons, Oxidation-Reduction, Molecular Biology, Perylene, Carcinogen
Abstract: To test the hypothesis that electrophilic radical cations are the major ultimate electrophilic and carcinogenic forms of benz[a]anthracene (BA), dibenz[a,h]anthracene (DBA), and benzo[a]pyrene (BP), we have focused on a chemical model of metabolism which parallels and duplicates known or potential metabolites of some polycyclic hydrocarbons formed in cells. Studies of this model system show that radical cations are hardly formed, if at all, in the case of BA or DBA but are definitely formed in the cases of the carcinogen BP as well as the non-carcinogenic hydrocarbons, pyrene and perylene. We conclude that the carcinogenicities of BA, DBA, BP, pyrene, and perylene are independent of one-electron oxidation to radical cation intermediates.
Published: 2004

285. Determination of Salmeterol in Equine Urine and Serum

Author: W. Karpiesiuk, Charlie Hughes, W. E. Woods, J. D. Harkins, A. Troppmann, Thomas Tobin, J. Bosken, F. C. Camargo, Andreas F. Lehner, and J. Boyles
Subjects: Agonist, Chromatography, Chemistry, medicine.drug_class, Organic Chemistry, Clinical Biochemistry, Horse, Urine, Biochemistry, High-performance liquid chromatography, Analytical Chemistry, Blood serum, Pharmacokinetics, Bronchodilator, medicine, Salmeterol, medicine.drug
Abstract: Salmeterol is a β2-adrenergic agonist and an Association of Racing Commissioners International (ARCI) class 3 drug. Trade names of its xinafoate salt are Arial (Dompe), Salmetedur (Menarini), and Serevent (Glaxo). Salmeterol is routinely used to increase ease of breathing in race horses during their training. Due to its bronchodilating and central nervous system stimulant properties, its administration to a horse just prior to race time has the potential to affect the horse’s performance, therefore a reliable method of analysis for this compound is necessary. This paper describes a method for the identification and quantitation of salmeterol in equine urine using liquid-liquid extraction followed by liquid chromatography and tandem mass spectrometry (LC-MS-MS). Urine salmeterol concentrations peaked at about 2 h post-dose following administration of 500 ug both intravenously and intratracheally at concentrations of 14 ng mL−1 and 4 ng mL−1, respectively. Serum concentrations at 30 min were below the minimum level of quantitation.
Published: 2004

286. Detection and Identification of Dizocilpine and its Major Urinary Metabolites in the Horse: A Preliminary Report

Author: W. Karpiesiuk, Andreas F. Lehner, J. Boyles, W. E. Woods, F. C. Camargo, J. D. Harkins, Charlie Hughes, and Thomas Tobin
Subjects: Chromatography, Metabolite, Organic Chemistry, Clinical Biochemistry, Antagonist, Biochemistry, Analytical Chemistry, Dizocilpine, chemistry.chemical_compound, chemistry, Pharmacokinetics, medicine, NMDA receptor, Hydroxymethyl, Glucuronide, Phencyclidine, medicine.drug
Abstract: Dizocilpine ([+]-10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine), is a potent and selective NMDA (N-methyl-D-aspartate) receptor antagonist, which acts by blocking receptor ion channels. Dizocilpine is pharmacologically related to ketamine and phencyclidine; as such, it has the potential to affect behavior and performance in horses, with particular efficacy at lower concentrations. We now report development of a sensitive method for the detection of dizocilpine and preliminary characterization of its urinary metabolites in the horse. Dizocilpine (MW 221) readily produces a protonated species [M+H]+ in formic acid, and yields a m/z 205 product ion in Multiple Reaction Monitoring (MRM), allowing highly sensitive detection of parent drug. The 17 AMU loss most likely represents an unusual loss of CH5 from the exocyclic methyl group. No unchanged dizocilpine was identified in unhydrolysed urine, and the presence of hydroxymethyl and carboxydizocilpine glucuronide metabolites were supported by observation of m/z 414→238 and 428→235 transitions. Urine samples from horses dosed with dizocilpine (0.0132 and 0.0656 mg kg−1, iv) were hydrolysed with glucuronidase and were found to contain dizocilpine and OH-dizocilpine. Tentatively identified phase I post-hydrolysis compounds include dizocilpine itself, an hydroxymethyl metabolite, two ring-hydroxylated metabolites, a di-hydroxy metabolite, and a carboxy-dizocilpine metabolite. Corresponding Phase II glucuronidated metabolites were also identified as well as a number of combination metabolites and a posssible n-glucuronide metabolite for a total of at least six identifiable urinary glucuronide metabolites. Among the phase I metabolites, the hydroxymethyl metabolite apparently predominated, especially at the 0.0132 mg kg−1 dose. The goal of this research was to identify a target analyte for dizocilpine in post-administration equine urine, so that work may begin on development of a forensically validated qualitative method for this target analyte. Given the likelihood that the doses of dizocilpine used in attempts to influence the behavior or performance of horses, either alone or in combination with other agents, are expected to be in the order of 0.02 mg kg−1 or less, these results suggest selection of the phase I hydroxymethyl metabolite of dizocilpine as the optimal target analyte for regulatory control of dizocilpine in performance horses.
Published: 2004

287. FORMATION OF BENZYLIC ALCOHOLS AND MESO-ALDEHYDES BY ONE-ELECTRON OXIDATION OF DMBA, A MODEL FOR THE FIRST METABOLIC STEP IN METHYLATED CARCINOGENIC HYDROCARBON ACTIVATION

Author: James W. Flesher, Andreas F. Lehner, and Jamie Horn
Subjects: endocrine system, Anthracene, Oxidative metabolism, Polymers and Plastics, Stereochemistry, Organic Chemistry, DMBA, Alcohol, Carcinogenic Hydrocarbon, Hydroxylation, chemistry.chemical_compound, chemistry, polycyclic compounds, Materials Chemistry, Organic chemistry, skin and connective tissue diseases, neoplasms, Carcinogen
Abstract: The hypothesis that hydroxylation of the 7-methyl group is the first step in metabolic activation of 7,12-dimethylbenz[a]anthracene (DMBA) was advanced over three decades ago (1, 2). A considerable body of evidence supports the hypothesis (3). A chemical model for the oxidative metabolism of DMBA may be useful in understanding the mechanism of metabolic activation of DMBA and other methylated carcinogenic hydrocarbons, particularly the first step. Here we show that a nonenzymatic one-electron oxidation pathway transforms DMBA to carcinogenic alcohol and meso-aldehyde metabolites. The results are consistent with the hypothesis that hydroxylation of the 7-methyl and/or 12-methyl groups is the first metabolic step in DMBA activation. The hypothesis predicts that hydroxylation of other meso-methyl-substituted hydrocarbons is the first essential step in the metabolic activation of methylated carcinogenic hydrocarbons.
Published: 2004

288. Mass spectrometric analysis of 7-sulfoxymethyl-12-methylbenz[a]anthracene and related electrophilic polycyclic aromatic hydrocarbon metabolites

Author: Andreas F. Lehner, Jamie Horn, and James W. Flesher
Subjects: chemistry.chemical_classification, Spectrometry, Mass, Electrospray Ionization, Anthracene, Hydrocarbons, Halogenated, Stereochemistry, 9,10-Dimethyl-1,2-benzanthracene, Electrospray ionization, Metabolite, Leaving group, Polycyclic aromatic hydrocarbon, Carbocation, Mass spectrometry, Xenobiotics, chemistry.chemical_compound, chemistry, Carbonium ion, Carcinogens, Polycyclic Aromatic Hydrocarbons, Spectroscopy
Abstract: The Meso-region theory of polycyclic aromatic hydrocarbon (PAH) carcinogenesis predicts that the development of pronounced carcinogenicity depends on the introduction of a good leaving group on alkyl side-chains attached to the exceptionally reactive meso-anthracenic or L-region positions of PAHs. Thus, the first step in carcinogenesis by methylated PAHs such as 7,12-dimethylbenz[a]anthracene (DMBA) would be the hydroxylation of the L-region methyl groups, particularly the 7-methyl group. The second would be the formation of a metabolite, e.g. a sulfate ester, which is expected to be a good leaving group capable of generating a highly reactive benzylic carbocation. 7-Hydroxymethyl-12-methylbenz[a]anthracene (7-HMBA) is a metabolite of DMBA, and sulfation of 7-HMBA to a 7-sulfoxymethyl metabolite (7-SMBA) is a known Phase II metabolic process designed to facilitate excretion, but actually enabling more destructive side-reactions. These side-reactions occur with generation of an electrophilic 7-methylene carbonium ion, and/or by in vivo halide exchange to provide neutral side-products more capable of entering cells, especially those of DMBA target tissues. Electrospray ionization mass spectrometry (MS) enabled us to visualize 7-SMBA as an intact m/z 351 conjugate anion by negative mode, and as a released m/z 255 carbonium ion by positive mode. Upon prolonged refrigeration, 7-SMBA accumulated an m/z 383 photooxide, which appeared capable of re-evolving the starting material as visualized by tandem quadrupole MS, or MS/MS. The 7-SMBA carbonium ion provided interpretable fragments when studied by fragment ion MS/MS, including those representing the loss of up to several protons. Subtle differences in this property were encountered upon perturbing 7-SMBA, either by warming it at 37 °C for 2 h or by substituting the initial sulfoxy group with an iodo group. Side-reactions accounting for such proton losses are proposed, and are of interest whether they occur in the mass spectrometer, in solution or both; these proposals include acidity at the 12-methyl position and cyclization between the 12-methyl group and the adjacent C-1 position. It is also suggested that such side-reactions may comprise one route to relieving steric strain arising between the 12-methyl group and the angular benzo ring of 7-SMBA. Copyright © 2004 John Wiley & Sons, Ltd.
Published: 2004

289. Search for 3- and 4-body decays of the scalar top quark in pp- collisions at root s = 1.8 TeV

Author: N. I. Bojko, D. O'Neil, Andrew White, A. Goussiou, A. Baden, Andrei Nomerotski, G. C. Blazey, John Hobbs, J. N. Butler, P. D. Grannis, J. Barreto, M. Buehler, Alexander Belyaev, S. Chopra, Ariel Schwartzman, Melissa Ridel, R. Kehoe, R. Yamada, Patrick Slattery, A. Khanov, N. Parua, V.V. Abramov, M. Jaffré, M. Abolins, H. L. Melanson, Elemer Nagy, N. R. Stanton, L. Duflot, E. W. Anderson, Arnaud Lucotte, C. Luo, Mary Beth Adams, Alexander Kupco, W. Kahl, S. Youssef, J. M. Hauptman, Cecilia Elena Gerber, Ulrich Heintz, D. Edmunds, James C. Green, N. K. Mondal, R. K. Shivpuri, D. Cutts, H. T. Diehl, T. A. Bolton, N.V. Mokhov, Marvin Johnson, H. Jöstlein, Q. Z. Li, Andre Sznajder, D. R. Claes, Frank Filthaut, Randy Ruchti, V. Zutshi, Wagner Carvalho, N. Sotnikova, R. J. Genik, M. I. Martin, Yuri Gershtein, Greg Landsberg, D. Whiteson, A. Boehnlein, A. V. Kozelov, V. V. Babintsev, David H. Adams, M. Diesburg, G. Ginther, Alice Bean, S. Duensing, Wendy Taylor, A. Patwa, P. Krivkova, D. Hedin, Roger Moore, S. Doulas, Sebastian Grinstein, K. Soustruznik, Shuichi Kunori, A. P. Heinson, A. N. Galyaev, V. Vaniev, L. Babukhadia, D. Shpakov, J. Ellison, A. K.A. Maciel, Sa. Jain, S. Fuess, Jianming Qian, A. Abdesselam, V. A. Bezzubov, S. J. De Jong, A. V. Kostritskiy, Michael A. Strauss, Kaushik De, F. Canelli, Volker Buescher, Vladimir Gavrilov, J. P. Negret, P. Demine, R. P. Smith, Gordon Watts, V. Sirotenko, H. Zheng, T. Nunnemann, B. Baldin, D. Coppage, F. Borcherding, D. K. Cho, Y. Arnoud, G. Sajot, D. A. Stoyanova, A. S. Turcot, B. Kothari, Vipin Bhatnagar, K. Gounder, O. V. Eroshin, Y. Song, G. Briskin, M. Strovink, Michael Shupe, Sissel Hansen, Michael Hildreth, S. M. Tripathi, Y. Kulik, R. E. Hall, P. I. Goncharov, R. Illingworth, L. Lueking, R. Partridge, X. Zhang, W. E. Cooper, J. Estrada, A. Leflat, Jeffrey F. Krane, N. A. Naumann, L. Coney, Suman Bala Beri, S. Baffioni, W. M. Lee, A. Kharchilava, Christos Leonidopoulos, Sarah Catherine Eno, S. N. Ahmed, S. Reucroft, Y. A. Yatsunenko, D. Chakraborty, Stephen Wimpenny, Harrison Prosper, Michael Begel, T. Marshall, Sergey Kuleshov, Christophe Royon, C. Miao, B. Olivier, Victor Daniel Elvira, V. L. Malyshev, B. M. Sabirov, A. Juste, F. Nang, E. Popkov, Richard B. Lipton, J. Womersley, Arnaud Duperrin, Heriberto Castilla-Valdez, S. Desai, V. M. Abazov, H. D. Wahl, D. Bauer, H. S. Mao, D. Fein, B. Connolly, Richard Breedon, M. Zanabria, Winston Ko, Pushpalatha C Bhat, U. Bassler, Jong-Sung Yu, V. Simak, C. Han, Don Lincoln, P. W. Balm, P. Padley, S. Tentindo-Repond, D. Karmanov, Alexey Volkov, A. Stone, Daniel John Karmgard, T. Rockwell, Iain Alexander Bertram, Michael Rijssenbeek, C. Hebert, M. Merkin, D. A. Wijngaarden, T. Yasuda, Mitchell Wayne, H. Schellman, J. M. Kohli, Ia Iashvili, T. C. Bacon, D. Mihalcea, E. Kajfasz, K. Bos, Zeno Dixon Greenwood, Stefan Grünendahl, Alberto Santoro, Philip Baringer, Raymond Brock, V. N. Evdokimov, M. A.C. Cummings, Boaz Klima, Bobby Samir Acharya, H. A. Neal, Jing Li, S. Banerjee, Mossadek Talby, B. Gómez, R. Beuselinck, D. Casey, J. T. Linnemann, V. Sorín, P. M. Tuts, V. E. Kuznetsov, P. Rubinov, K. Yip, S. Krzywdzinski, J. Kotcher, Shashikant Dugad, Harald Fox, D. P. Stoker, B. G. Pope, S. Willis, L. Stutte, A.S. Dyshkant, B. Hoeneisen, Lee Sawyer, N. Graf, Y. D. Mutaf, Robert Hirosky, H. E. Fisk, A. Zylberstejn, F. Fleuret, Elizaveta Shabalina, A. M. Kalinin, F. Lehner, H. Greenlee, Z. Zhou, J. Solomon, R. Demina, A. Bross, O. Peters, G. A. Davis, Elizabeth Gallas, T. McMahon, Serban Protopopescu, G. Gutierrez, Gilvan Alves, V. S. Narasimham, L. Groer, A. A. Mayorov, J. Snow, M. Gao, J. T. Eltzroth, S.A. Kahn, R. Jesik, K. A. Johns, M. Demarteau, G. Bernardi, V. Oguri, Gustaaf Brooijmans, J. Warchol, P. Yamin, G. D. Alexeev, Flera Rizatdinova, P. A. Rapidis, A. Jonckheere, A. P. Vorobiev, Stephan Linn, M. Sosebee, N. Oshima, Daria Zieminska, R. D. Schamberger, M. A. Kubantsev, Freya Blekman, Andrew Brandt, R. Engelmann, E. A. Kozlovsky, H.E. Miettinen, E. G. Zverev, Meenakshi Narain, G. Eppley, H. da Motta, J. G.R. Lima, S. N. Gurzhiev, A. S. Ito, Viatcheslav Stolin, C. Lundstedt, Carlos Avila, Sabine Crépé-Renaudin, Neeti Parashar, R. L. McCarthy, M. Zielinski, Suyong Choi, D. Denisov, J. M. Heinmiller, Srinivasan Rajagopalan, Hal Evans, Thomas Ferbel, M. H.G. Souza, H. E. Montgomery, R. Van Kooten, A. Besson, P.F. Ermolov, A. Zieminski, V. S. Burtovoi, R. A. Sidwell, R. J. Madaras, D. Buchholz, Florian Beaudette, J. Huang, Gregory R Snow, G. Steinbrück, K. Genser, M. B. Przybycien, Rajendran Raja, Phillip Gutierrez, M. A. Strang, Emanuela Barberis, Vasken Hagopian, H. Weerts, Z. M. Wang, Brad Abbott, Lev Dudko, F. Villeneuve-Seguier, Tulika Bose, Pierre Petroff, H. Haggerty, M. Fortner, N. W. Reay, S. Fu, Q. Xu, Darien Wood, Nicholas John Hadley, S. Blessing, Scott Snyder, M. Bhattacharjee, T. G. Trippe, Howard Gordon, Yu-tin Huang, Nikos Varelas, Bing Zhou, Sharon Hagopian, K. Papageorgiou, S. P. Denisov, M. R. Krishnaswamy, R. Piegaia, A. R. Clark, A. Alton, Sergey Chekulaev, K. M. Chan, K. W. Merritt, J. F. Bartlett, V. Manankov, and D0 (Tevatron, IHEF, IOP, FNWI)
Subjects: Quark, Physics, Particle physics, Top quark, Nuclear and High Energy Physics, Muon, 010308 nuclear & particles physics, Scalar (mathematics), High Energy Physics::Phenomenology, 01 natural sciences, Lightest Supersymmetric Particle, Nuclear physics, 0103 physical sciences, Neutralino, High Energy Physics::Experiment, Fermilab, 010306 general physics, Minimal Supersymmetric Standard Model
Abstract: We have searched for the signature of 3- and 4-body decays of pair-produced scalar top quarks (stop) in the inclusive final state containing an electron, a muon, and significant missing transverse energy using a sample of p p events corresponding to 108.3 pb−1 of data collected with the DO detector at Fermilab. The search is done in the framework of the minimal supersymmetric standard model assuming that the neutralino ( χ 0 1 ) is the lightest supersymmetric particle and is stable. No evidence for a signal is found and we derive cross-section upper limits as a function of stop (t) and neutralino masses in different decay scenarios leading to the blν χ 0 1 final state.
Published: 2004

290. The metabolism of formyl-substituted benzanthracenes to hydroxymethyl metabolites in rat liver in vitro and in vivo

Author: James W. Flesher, Jamie Horn, and Andreas F. Lehner
Subjects: Male, inorganic chemicals, In Vitro Techniques, Carbocation, Toxicology, Benzanthracene, Gas Chromatography-Mass Spectrometry, Rats, Sprague-Dawley, Hydroxylation, chemistry.chemical_compound, Benz(a)Anthracenes, polycyclic compounds, Animals, Organic chemistry, Hydroxymethyl, Biotransformation, Chromatography, High Pressure Liquid, Carcinogen, organic chemicals, General Medicine, Metabolism, BSTFA, Rats, Liver, chemistry, Electrophile, Carcinogens, Female, Chromatography, Thin Layer
Abstract: Hydroxylation of benzylic methyl carbon atoms on drugs and carcinogenic polycyclic aromatic hydrocarbons (PAHs) forms benzylic alcohols. Many carcinogenic and mutagenic PAHs bear a primary or secondary benzylic hydroxyl group attached to the meso-region of the molecule. According to the unified theory, PAHs bearing a benzylic hydroxyl group are proximate carcinogenic metabolites. This paper demonstrates that carcinogenic benz[a]anthracenes bearing a formyl group at the meso-region undergo enzymatic reductive metabolism to the corresponding carcinogenic benzylic alcohol in vitro and in vivo. The unified theory would then predict sulfuric acid esterification of such benzylic alcohols as the final common step in their metabolic activation to generate ultimate electrophilic benzylic carbocations. Finally, oxidative metabolism of 7-formylbenz[a]anthracenes gives rise to corresponding carboxylic acids and other oxygenated metabolites that are carcinogenically inert. Thus, oxidative metabolism of meso-region formyl compounds represents an avenue for the elimination of the carcinogen in a detoxified form.
Published: 2003

291. Completion of Mitosis Requires Neither fzr/rap nor fzr2, a Male Germline-Specific Drosophila Cdh1 Homolog

Author: David O. Richter, Tadmiri Venkatesh, Christian F. Lehner, and Henning W. Jacobs
Subjects: Male, Embryo, Nonmammalian, Saccharomyces cerevisiae Proteins, Recombinant Fusion Proteins, Cyclin B, Mitosis, Cell Cycle Proteins, CDC20, General Biochemistry, Genetics and Molecular Biology, Cdh1 Proteins, Tubulin, Animals, Drosophila Proteins, Amino Acid Sequence, In Situ Hybridization, Cyclin, biology, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Molecular biology, Cell biology, body regions, Meiosis, Drosophila melanogaster, Essential gene, Mitotic exit, biology.protein, Female, RNA Interference, General Agricultural and Biological Sciences, Cytokinesis
Abstract: Proteolysis of mitotic regulators like securins and cyclins requires Fizzy(FZY)/Cdc20 and Fizzy-related(FZR)/Hct1/Cdh1 proteins [1–5]. Budding yeast Cdh1 acts not only during G1, but is also required for B-type cyclin degradation during exit from mitosis when Cdh1 is a target of the mitotic exit network controlling progression through late mitosis and cytokinesis [6, 7]. In contrast, observations in frog and Drosophila embryos have suggested that the orthologous FZR is not involved during exit from mitosis [3, 8]. However, the potential involvement of minor amounts of maternally derived FZR was not excluded in these studies. Similarly, the reported absence of severe mitotic defects in chicken Cdh1 −/− cells [9] might be explained by the recent identification of multiple Cdh1 genes [10]. Here, we have carefully analyzed the FZR requirement during exit from mitosis in Drosophila , which, apart from fzr , has only one additional homolog. We find that this fzr2 gene, although expressed in the male germline, is not expressed during mitotic divisions. Moreover, by characterizing fzr alleles, we demonstrate that completion of mitosis including Cyclin B degradation does not require FZR. However, fzr is an essential gene corresponding to the rap locus, and FZR, which accumulates predominantly in the cytoplasm, is clearly required during G1.
Published: 2002
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292. Hard single diffraction in p̄p collisions at s=630 and 1800 GeV

Author: A. N. Galyaev, D. K. Cho, Y. Arnoud, M. Merkin, R. Illingworth, Raymond Brock, Boaz Klima, R. Beuselinck, S. Willis, W. E. Cooper, S. Duensing, G. Eppley, Arnaud Duperrin, M. A. Strang, S. J. De Jong, Jong-Sung Yu, C. S. Mishra, S. Fu, B. Kothari, N.V. Mokhov, H. da Motta, J. G.R. Lima, M. Sosebee, V. M. Abazov, M. I. Martin, K. W. Merritt, Elemer Nagy, Vasken Hagopian, L. Lueking, H. Weerts, W. Kahl, Andrew White, J. F. Bartlett, A. P. Heinson, V. Manankov, E. W. Anderson, Q. Xu, Lev Dudko, T. G. Trippe, A. S. Ito, P. Pétroff, E. Kajfasz, E. Popkov, R. E. Hall, B. Pawlik, Q. Z. Li, Sharon Hagopian, K. Papageorgiou, Wendy Taylor, T. Rockwell, Iain Alexander Bertram, N. Parua, A. Goussiou, Roger Moore, S. Fuess, Michael Rijssenbeek, D. Mihalcea, D. Casey, S. Krzywdzinski, Sebastian Grinstein, B. Olivier, Neeti Parashar, J. Kotcher, A. Patwa, Anurag Gupta, R. Van Kooten, Z. M. Wang, L. Babukhadia, Vladimir Gavrilov, R. Piegaia, V. Oguri, Gordon Watts, R. Snihur, P. M. Tuts, V. E. Kuznetsov, Harald Fox, A. Zylberstejn, Shuichi Kunori, N. Graf, R. W. Stephens, Robert Hirosky, A. V. Kostritskiy, V. Sirotenko, Andrew Brandt, A. Abdesselam, A. M. Kalinin, H. E. Fisk, L. J. Pan, Z. Zhou, J. Solomon, Vipin Bhatnagar, K. Gounder, A. Alton, Andrei Nomerotski, John Hobbs, F. Lehner, H. Greenlee, V. N. Evdokimov, Gustaaf Brooijmans, B. M. Sabirov, O. V. Eroshin, Y. Song, Phillip Gutierrez, A. Bross, Sissel Hansen, T. Nunnemann, B. Baldin, E. A. Kozlovsky, H.E. Miettinen, D. Edmunds, D. Bauer, V. Vaniev, Howard Gordon, K. C. Frame, Chris Hays, M. Zielinski, R. Partridge, X. Zhang, J. Barreto, A. Khanov, R. Demina, A. Zieminski, G. A. Davis, L. Coney, G. Gutierrez, V. A. Bezzubov, V.V. Abramov, N. Sen, R. Gilmartin, Serban Protopopescu, A. Besson, J. P. Negret, Y. Ducros, V. L. Malyshev, Gilvan Alves, Heriberto Castilla-Valdez, R. L. McCarthy, J. Warchol, Andre Sznajder, R. P. Smith, M. Gao, M. Bhattacharjee, H. S. Mao, S. P. Denisov, W. M. Lee, A. Kharchilava, B. G. Pope, P. Demine, V. S. Narasimham, L. Groer, Yuri Gershtein, J. M. Hauptman, Cecilia Elena Gerber, Arnaud Lucotte, Michael Shupe, Michael Hildreth, K. M. Chan, Dhiman Chakraborty, T. Fahland, H. Zheng, S. N. Gurzhiev, M. R. Krishnaswamy, D. Fein, V. Simak, Alexander Kupco, J. Estrada, Sergey Kuleshov, E. G. Zverev, V. V. Babintsev, D. Coppage, B. Abbott, G. Ginther, A. A. Mayorov, Don Lincoln, P. Padley, V. Zutshi, Alexey Volkov, Y. A. Yatsunenko, P. Krivkova, A. R. Clark, N. Sotnikova, Jianming Qian, P. W. Balm, A. Stone, Daniel John Karmgard, A. V. Kotwal, Harrison Prosper, M. Roco, R. J. Genik, Elizabeth Gallas, T. McMahon, Randy Ruchti, Mitchell Wayne, H. Schellman, J. M. Kohli, Victor Daniel Elvira, Sergey Chekulaev, J. Snow, C. Hebert, G. Briskin, H. L. Melanson, N. A. Naumann, Stefan Grünendahl, R. A. Sidwell, E. Flattum, Christophe Royon, Jeffrey F. Krane, Viatcheslav Stolin, N. I. Bojko, Mossadek Talby, B. Gómez, Ulrich Heintz, Marc M Baarmand, S. Reucroft, J. H. Christenson, Meenakshi Narain, D. O'Neil, S. Chopra, H. D. Wahl, Elizaveta Shabalina, Shashikant Dugad, C. Lundstedt, M. Strovink, David H. Adams, M. Zanabria, Winston Ko, Carlos Avila, Jing Li, Michael A. Strauss, Alice Bean, Sabine Crépé-Renaudin, H. Jöstlein, M. Jaffré, Ariel Schwartzman, E. Smith, U. Bassler, F. Blekman, Suyong Choi, O. Peters, F. Canelli, Volker Buescher, J. T. Eltzroth, Melissa Ridel, R. Kehoe, J. T. White, G. Steinbrück, J. N. Butler, P. D. Grannis, R. Jesik, Laurent Duflot, T. Yasuda, Frank Filthaut, D. Hedin, Rajendran Raja, K. A. Johns, Alberto Santoro, Seong Keun Kim, M. Diesburg, A. Leflat, S. Youssef, P. Rubinov, Gregorio Bernardi, Suman Bala Beri, D. Denisov, J. M. Heinmiller, Srinivasan Rajagopalan, D. Shpakov, A. Juste, Bobby Samir Acharya, H. A. Neal, S. Tentindo-Repond, Hal Evans, Thomas Ferbel, T. C. Bacon, J. T. Linnemann, V. Sorín, B. Connolly, K. Yip, Richard Breedon, D. P. Stoker, L. Stutte, A.S. Dyshkant, Alexander Belyaev, Philip Baringer, Patrick Slattery, D. A. Stoyanova, A. S. Turcot, S. Banerjee, Zeno Dixon Greenwood, D. A. Wijngaarden, Michael Begel, K. Bos, K. Genser, M. Buehler, M. Chung, R. D. Schamberger, Y. Fisyak, N. R. Stanton, Christos Leonidopoulos, J. Womersley, Marvin Johnson, M. Abolins, D. Karmanov, Z. Casilum, Ia Iashvili, A. V. Kozelov, N. K. Mondal, H. T. Diehl, T. A. Bolton, H. Singh, D. Whiteson, A. Boehnlein, J. Ellison, A. K.A. Maciel, Sa. Jain, P. I. Goncharov, C. Miao, Pushpalatha C Bhat, M. H.G. Souza, H. E. Montgomery, M. A.C. Cummings, B. Hoeneisen, D. Buchholz, Lee Sawyer, Gregory R Snow, P.F. Ermolov, B. Knuteson, V. S. Burtovoi, R. J. Madaras, Haiyan Wang, S.A. Kahn, M. Demarteau, F. Borcherding, S. Desai, G. Sajot, E. J. Ramberg, P. Yamin, G. D. Alexeev, Flera Rizatdinova, Miguel Mostafa, Sarah Catherine Eno, P. A. Rapidis, François Fleuret, F. Nang, A. Jonckheere, A. P. Vorobiev, Richard B. Lipton, F. Villeneuve-Seguier, Stephan Linn, A. Baden, N. Oshima, Daria Zieminska, G. C. Blazey, M. A. Kubantsev, Stephen Wimpenny, T. Marshall, R. Yamada, Darien Wood, Nicholas John Hadley, S. Blessing, Scott Snyder, R. K. Shivpuri, John Rutherfoord, D. R. Claes, C. Luo, Mary Beth Adams, S. Doulas, James C. Green, Kaushik De, Emanuela Barberis, D. Cutts, Wagner Carvalho, Greg Landsberg, L. T. Goss, Charles Leggett, Y. Kulik, M. Paterno, K. Soustruznik, Tulika Bose, H. Haggerty, F. Beaudette, M. B. Przybycien, S. M. Tripathi, R. Engelmann, S. N. Ahmed, M. Fortner, N. W. Reay, Y. D. Mutaf, Yu-tin Huang, Nikos Varelas, Bing Zhou, and L. S. Vertogradov
Subjects: Diffraction, Physics, Particle physics, Nuclear and High Energy Physics, 010308 nuclear & particles physics, Detector, Empty set, HERA, Jet (particle physics), 01 natural sciences, Nuclear physics, Pomeron, 0103 physical sciences, Momentum loss, Rapidity, High Energy Physics::Experiment, 010306 general physics
Abstract: Using the D empty set detector, we have studied events produced in (p) over barp collisions that contain large forward regions with very little energy deposition ("rapidity gaps") and concurrent jet production at center-of-mass energies of roots = 630 and 1800 GeV. The fraction of events with forward or central jets associated with rapidity gaps is compared to predictions for hard diffraction. We also extract the momentum loss for scattered protons in such processes. (C) 2002 Elsevier Science B.V. All rights reserved.
Published: 2002
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293. The Meso-Region Theory of Aromatic Hydrocarbon Carcinogenesis

Author: Andreas F. Lehner, James W. Flesher, and Jamie Horn
Subjects: chemistry.chemical_classification, Substitution reaction, Anthracene, Polymers and Plastics, fungi, Organic Chemistry, Leaving group, Medicinal chemistry, carbohydrates (lipids), Electrophilic substitution, chemistry.chemical_compound, chemistry, Carbonium ion, polycyclic compounds, Materials Chemistry, Side chain, Aromatic hydrocarbon, Methyl group
Abstract: Structure-activity relationships (SAR) demonstrate the importance, for carcinogenic activity in polycyclic aromatic hydrocarbons (PAHs), of substituents at meso-regions of exceptional reactivity whether located in an aromatic nucleus or on a side chain. The simplest SAR is that a majority of carcinogenic hydrocarbons can be classified as anthracene derivatives. The meso-region theory proposes that the chemical and biochemical pathways of activation of both unsubstituted and meso-substituted PAHs are essentially the same. The first biochemical step, in a chain of three substitution reactions, involves the methylation of unsubstituted PAHs, at a meso-center of exceptional reactivity. Hydroxylation of a meso-region methyl group is followed by the formation of a reactive ester (e.g., sulfuric acid ester) bearing a good leaving group, which would be expected to generate a highly reactive carbonium ion. The carbonium ion would be expected to react with critical nucleophiles to initiate the chain of cellular eve...
Published: 2002

294. The inclusive jet cross section in p collisions at =1.8 TeV using the k⊥ algorithm

Author: V.M Abazov, B Abbott, A Abdesselam, M Abolins, V Abramov, B.S Acharya, D.L Adams, M Adams, S.N Ahmed, G.D Alexeev, A Alton, G.A Alves, N Amos, E.W Anderson, Y Arnoud, C Avila, M.M Baarmand, V.V Babintsev, L Babukhadia, T.C Bacon, A Baden, B Baldin, P.W Balm, S Banerjee, E Barberis, P Baringer, J Barreto, J.F Bartlett, U Bassler, D Bauer, A Bean, F Beaudette, M Begel, A Belyaev, S.B Beri, G Bernardi, I Bertram, A Besson, R Beuselinck, V.A Bezzubov, P.C Bhat, V Bhatnagar, M Bhattacharjee, G Blazey, F Blekman, S Blessing, A Boehnlein, N.I Bojko, F Borcherding, K Bos, T Bose, A Brandt, R Breedon, G Briskin, R Brock, G Brooijmans, A Bross, D Buchholz, M Buehler, V Buescher, V.S Burtovoi, J.M Butler, F Canelli, W Carvalho, D Casey, Z Casilum, H Castilla-Valdez, D Chakraborty, K.M Chan, S.V Chekulaev, D.K Cho, S Choi, S Chopra, J.H Christenson, M Chung, D Claes, A.R Clark, L Coney, B Connolly, W.E Cooper, D Coppage, S Crépé-Renaudin, M.A.C Cummings, D Cutts, G.A Davis, K Davis, K De, S.J de Jong, K Del Signore, M Demarteau, R Demina, P Demine, D Denisov, S.P Denisov, S Desai, H.T Diehl, M Diesburg, S Doulas, Y Ducros, L.V Dudko, S Duensing, L Duflot, S.R Dugad, A Duperrin, A Dyshkant, D Edmunds, J Ellison, J.T Eltzroth, V.D Elvira, R Engelmann, S Eno, G Eppley, P Ermolov, O.V Eroshin, J Estrada, H Evans, V.N Evdokimov, T Fahland, S Feher, D Fein, T Ferbel, F Filthaut, H.E Fisk, Y Fisyak, E Flattum, F Fleuret, M Fortner, H Fox, K.C Frame, S Fu, S Fuess, E Gallas, A.N Galyaev, M Gao, V Gavrilov, R.J Genik, K Genser, C.E Gerber, Y Gershtein, R Gilmartin, G Ginther, B Gómez, G Gómez, P.I Goncharov, J.L González Solı́s, H Gordon, L.T Goss, K Gounder, A Goussiou, N Graf, G Graham, P.D Grannis, J.A Green, H Greenlee, Z.D Greenwood, S Grinstein, L Groer, S Grünendahl, A Gupta, S.N Gurzhiev, G Gutierrez, P Gutierrez, N.J Hadley, H Haggerty, S Hagopian, V Hagopian, R.E Hall, P Hanlet, S Hansen, J.M Hauptman, C Hays, C Hebert, D Hedin, J.M Heinmiller, A.P Heinson, U Heintz, M.D Hildreth, R Hirosky, J.D Hobbs, B Hoeneisen, Y Huang, I Iashvili, R Illingworth, A.S Ito, M Jaffré, S Jain, R Jesik, K Johns, M Johnson, A Jonckheere, H Jöstlein, A Juste, W Kahl, S Kahn, E Kajfasz, A.M Kalinin, D Karmanov, D Karmgard, R Kehoe, A Khanov, A Kharchilava, S.K Kim, B Klima, B Knuteson, W Ko, J.M Kohli, A.V Kostritskiy, J Kotcher, B Kothari, A.V Kotwal, A.V Kozelov, E.A Kozlovsky, J Krane, M.R Krishnaswamy, P Krivkova, S Krzywdzinski, M Kubantsev, S Kuleshov, Y Kulik, S Kunori, A Kupco, V.E Kuznetsov, G Landsberg, W.M Lee, A Leflat, C Leggett, F Lehner, C Leonidopoulos, J Li, Q.Z Li, X Li, J.G.R Lima, D Lincoln, S.L Linn, J Linnemann, R Lipton, A Lucotte, L Lueking, C Lundstedt, C Luo, A.K.A Maciel, R.J Madaras, V.L Malyshev, V Manankov, H.S Mao, T Marshall, M.I Martin, K.M Mauritz, A.A Mayorov, R McCarthy, T McMahon, H.L Melanson, M Merkin, K.W Merritt, C Miao, H Miettinen, D Mihalcea, C.S Mishra, N Mokhov, N.K Mondal, H.E Montgomery, R.W Moore, M Mostafa, H da Motta, E Nagy, F Nang, M Narain, V.S Narasimham, N.A Naumann, H.A Neal, J.P Negret, S Negroni, T Nunnemann, D O'Neil, V Oguri, B Olivier, N Oshima, P Padley, L.J Pan, K Papageorgiou, A Para, N Parashar, R Partridge, N Parua, M Paterno, A Patwa, B Pawlik, J Perkins, O Peters, P Pétroff, R Piegaia, B.G Pope, E Popkov, H.B Prosper, S Protopopescu, M.B Przybycien, J Qian, R Raja, S Rajagopalan, E Ramberg, P.A Rapidis, N.W Reay, S Reucroft, M Ridel, M Rijssenbeek, F Rizatdinova, T Rockwell, M Roco, C Royon, P Rubinov, R Ruchti, J Rutherfoord, B.M Sabirov, G Sajot, A Santoro, L Sawyer, R.D Schamberger, H Schellman, A Schwartzman, N Sen, E Shabalina, R.K Shivpuri, D Shpakov, M Shupe, R.A Sidwell, V Simak, H Singh, J.B Singh, V Sirotenko, P Slattery, E Smith, R.P Smith, R Snihur, G.R Snow, J Snow, S Snyder, J Solomon, Y Song, V Sorı́n, M Sosebee, N Sotnikova, K Soustruznik, M Souza, N.R Stanton, G Steinbrück, R.W Stephens, F Stichelbaut, D Stoker, V Stolin, A Stone, D.A Stoyanova, M.A Strang, M Strauss, M Strovink, L Stutte, A Sznajder, M Talby, W Taylor, S Tentindo-Repond, S.M Tripathi, T.G Trippe, A.S Turcot, P.M Tuts, V Vaniev, R Van Kooten, N Varelas, L.S Vertogradov, F Villeneuve-Seguier, A.A Volkov, A.P Vorobiev, H.D Wahl, H Wang, Z.-M Wang, J Warchol, G Watts, M Wayne, H Weerts, A White, J.T White, D Whiteson, D.A Wijngaarden, S Willis, S.J Wimpenny, J Womersley, D.R Wood, Q Xu, R Yamada, P Yamin, T Yasuda, Y.A Yatsunenko, K Yip, S Youssef, J Yu, Z Yu, M Zanabria, X Zhang, H Zheng, B Zhou, Z Zhou, M Zielinski, D Zieminska, A Zieminski, V Zutshi, E.G Zverev, and A Zylberstejn
Subjects: Physics, Quantum chromodynamics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, Tevatron, Jet (particle physics), 7. Clean energy, 01 natural sciences, law.invention, Cross section (physics), law, Pseudorapidity, 0103 physical sciences, Transverse momentum, High Energy Physics::Experiment, Fermilab, 010306 general physics, Collider, Algorithm
Abstract: The central inclusive jet cross section has been measured using a successive-combination algorithm for reconstruction of jets. The measurement uses 87.3 pb^{-1} of data collected with the D0 detector at the Fermilab Tevatron ppbar Collider during 1994-1995. The cross section, reported as a function of transverse momentum (pT>60 GeV) in the central region of pseudorapidity (|\eta
Published: 2002

295. Comparative Carcinogenicity of Picene and Dibenz[a,h]anthracene in the Rat

Author: Jamie Horn, James W. Flesher, and Andreas F. Lehner
Subjects: Time Factors, Stereochemistry, Biophysics, Pharmacology, Biochemistry, Chrysenes, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Neoplasms, Benz(a)Anthracenes, Animals, Dibenz(a,h)anthracene, Carcinogenicity Test, Molecular Biology, Chromatography, High Pressure Liquid, Carcinogen, Anthracene, Dose-Response Relationship, Drug, Cell Biology, Hydrocarbons, Rats, Models, Chemical, chemistry, Picene, Nmri mice, Carcinogens, Female
Abstract: Early carcinogenicity tests found no evidence of activity for picene but found considerable initiating and carcinogenic activity for dibenz[ a,h ]anthracene (DBA). More recent investigation suggested that both pentacyclics were complete carcinogens when administered as single sc injections in NMRI mice, despite findings that picene acted as neither an initiating nor promoting agent. To investigate this contradiction, the complete carcinogenicities of both isomers were compared by sc injection in female Sprague–Dawley rats. The results demonstrate that 1 μmol of DBA, administered three times weekly for 20 doses, induces sarcomas in all test animals by 33 weeks (100%). Similar treatment with picene did not induce sarcoma in any test animals by 37 weeks (0%). The present results agree with the earlier studies. It follows from these results that the predictions of the unified theory for the appearance of carcinogenic properties following administration of picene and dibenz[ a,h ]anthracene to test animals have been confirmed.
Published: 2002

296. Mass Spectral Analysis of Unstable N7-Aralkyl DNA Adducts Resulting from Reaction of 7-Sulfooxymethyl-12-methylbenz[ a ]anthracene (SMBA) with DNA and Deoxynucleotides

Author: Andreas F. Lehner, James W. Flesher, and Jamie Horn
Subjects: Purine, Anthracene, Polymers and Plastics, Pyrimidine, Guanine, Stereochemistry, Organic Chemistry, DMBA, Photochemistry, chemistry.chemical_compound, chemistry, DNA adduct, Materials Chemistry, Nucleic acid, DNA
Abstract: The unified hypothesis for PAH activation predicts that SMBA plays a role in the metabolic activation and carcinogenicity of 7,12-dimethylbenz[ a ]anthracene (DMBA). SMBA and closely related aralkylating agents are derived from 7-hydroxymethyl-12-methylbenz[ a ]anthracene (HMBA), a direct metabolite of DMBA, and react with bases in nucleic acids. This occurs by generation of a benzylic carbonium ion owing to the fact that sulfate is a good leaving group. Previous characterization of reaction products with deoxynucleotide-3'-monophosphates detected stable adducts as primarily resulting from reaction with adenine at the N6- and guanine at the N2-amino groups, respectively. Pyrimidine adducts were also found; however, examination of SMBA-reacted DNA confirmed that the purine bases were the major targets for reaction. We now report evidence for the formation of unstable DNA adducts, most likely by reaction with purine N-7 positions. Treatment of SMBA-reacted DNA with formic acid at 70°C for 60 min and examina...
Published: 2002

297. Supplementary material to 'Reconciling reconstructed and simulated features of the winter Pacific–North-American pattern in the early 19th century'

Author: D. Zanchettin, O. Bothe, F. Lehner, P. Ortega, C. C. Raible, and D. Swingedouw
Published: 2014

298. Reconciling reconstructed and simulated features of the winter Pacific–North-American pattern in the early 19th century

Author: D. Zanchettin, O. Bothe, F. Lehner, P. Ortega, C. C. Raible, and D. Swingedouw
Subjects: 010504 meteorology & atmospheric sciences, 13. Climate action, 010502 geochemistry & geophysics, 01 natural sciences, 0105 earth and related environmental sciences
Abstract: Reconstructions of past climate behavior often describe prominent anomalous periods that are not necessarily captured in climate simulations. Here, we illustrate the contrast between an interdecadal strong positive phase of the winter Pacific/North American pattern (PNA) in the early 19th century that is described by a PNA reconstruction based on tree-rings from northwestern North America, and a slight tendency towards negative winter PNA anomalies during the same period in an ensemble of state-of-the-art coupled climate simulations. Additionally, a pseudo-proxy investigation with the same simulation ensemble allows assessing the robustness of PNA reconstructions using solely geophysical predictors from northwestern North America for the last millennium. The reconstructed early-19th-century positive PNA anomaly emerges as a potentially reliable feature, although it is subject to a number of sources of uncertainty and potential deficiencies. The pseudo-reconstructions demonstrate that the early-19th-century discrepancy between reconstructed and simulated PNA does not stem from the reconstruction process. Instead, reconstructed and simulated features of the early-19th-century PNA can be reconciled by interpreting the reconstructed evolution during this time as an expression of internal climate variability, hence unlikely to be reproduced in its exact temporal occurrence by a small ensemble of climate simulations. However, firm attribution of the reconstructed PNA anomaly is hampered by known limitations and deficiencies of coupled climate models and uncertainties in the early-19th-century external forcing and background climate conditions.
Published: 2014

299. Towards long term cultivation of Drosophila wing imaginal discs in vitro

Author: Christian F. Lehner, János Szabad, Peter V. Lidsky, Björn Handke, Ernst Hafen, and University of Zurich
Subjects: Organogenesis, Morphogenesis, lcsh:Medicine, 1100 General Agricultural and Biological Sciences, In Vitro Techniques, Cell Growth, 1300 General Biochemistry, Genetics and Molecular Biology, Live cell imaging, Hemolymph, Animals, Drosophila Proteins, Wings, Animal, Cell Cycle and Cell Division, lcsh:Science, Cell Proliferation, 1000 Multidisciplinary, Multidisciplinary, biology, Cell growth, lcsh:R, Cell Cycle, Gene Expression Regulation, Developmental, Biology and Life Sciences, Cell Biology, Cell cycle, biology.organism_classification, 10124 Institute of Molecular Life Sciences, Coculture Techniques, Cell biology, Culture Media, Transplantation, Imaginal disc, Drosophila melanogaster, Imaginal Discs, Cell Processes, Larva, 570 Life sciences, lcsh:Q, Developmental biology, Organism Development, Developmental Biology, Research Article, Signal Transduction, Insulin-Dependent Signal Transduction
Abstract: The wing imaginal disc of Drosophila melanogaster is a prominent experimental system for research on control of cell growth, proliferation and death, as well as on pattern formation and morphogenesis during organogenesis. The precise genetic methodology applicable in this system has facilitated conceptual advances of fundamental importance for developmental biology. Experimental accessibility and versatility would gain further if long term development of wing imaginal discs could be studied also in vitro. For example, culture systems would allow live imaging with maximal temporal and spatial resolution. However, as clearly demonstrated here, standard culture methods result in a rapid cell proliferation arrest within hours of cultivation of dissected wing imaginal discs. Analysis with established markers for cells in S- and M phase, as well as with RGB cell cycle tracker, a novel reporter transgene, revealed that in vitro cultivation interferes with cell cycle progression throughout interphase and not just exclusively during G1. Moreover, quantification of EGFP expression from an inducible transgene revealed rapid adverse effects of disc culture on basic cellular functions beyond cell cycle progression. Disc transplantation experiments confirmed that these detrimental consequences do not reflect fatal damage of imaginal discs during isolation, arguing clearly for a medium insufficiency. Alternative culture media were evaluated, including hemolymph, which surrounds imaginal discs during growth in situ. But isolated larval hemolymph was found to be even less adequate than current culture media, presumably as a result of conversion processes during hemolymph isolation or disc culture. The significance of prominent growth-regulating pathways during disc culture was analyzed, as well as effects of insulin and disc co-culture with larval tissues as potential sources of endocrine factors. Based on our analyses, we developed a culture protocol that prolongs cell proliferation in cultured discs., PLoS ONE, 9 (9), ISSN:1932-6203
Published: 2014

300. O-GlcNAc reports ambient temperature and confers heat resistance on ectotherm development

Author: Daniel Mariappa, Faina Myachina, H.-Arno J. Müller, Pablo T. Radermacher, Fritz Bosshardt, Christian F. Lehner, Rahul Pandey, University of Zurich, and Lehner, Christian F
Subjects: Acclimatization, Immunoblotting, Danio, Fluorescent Antibody Technique, Acetylglucosamine, Species Specificity, Melanogaster, Transferase, Animals, Nuclear protein, Caenorhabditis elegans, Crosses, Genetic, Zebrafish, chemistry.chemical_classification, 1000 Multidisciplinary, Multidisciplinary, biology, Ecology, fungi, Temperature, Biological Sciences, biology.organism_classification, Clutch Size, 10124 Institute of Molecular Life Sciences, Cell biology, Enzyme, Drosophila melanogaster, chemistry, Cytoplasm, Ectotherm, 570 Life sciences, Protein Processing, Post-Translational
Abstract: Effects of temperature on biological processes are complex. Diffusion is less affected than the diverse enzymatic reactions that have distinct individual temperature profiles. Hence thermal fluctuations pose a formidable challenge to ectothermic organisms in which body temperature is largely dictated by the ambient temperature. How cells in ectotherms cope with the myriad disruptive effects of temperature variation is poorly understood at the molecular level. Here we show that nucleocytoplasmic posttranslational modification of proteins with O-linked GlcNAc (O-GlcNAc) is closely correlated with ambient temperature during development of distantly related ectotherms ranging from the insect Drosophila melanogaster to the nematode Caenorhabditis elegans to the fish Danio rerio. Regulation seems to occur at the level of activity of the only two enzymes, O-GlcNAc transferase and O-GlcNAcase, that add and remove, respectively, this posttranslational modification in nucleus and cytoplasm. With genetic approaches in D. melanogaster and C. elegans, we demonstrate the importance of high levels of this posttranslational modification for successful development at elevated temperatures. Because many cytoplasmic and nuclear proteins in diverse pathways are O-GlcNAc targets, temperature-dependent regulation of this modification might contribute to an efficient coordinate adjustment of cellular processes in response to thermal change.
Published: 2014

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