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804 results on '"Damen J"'

252. Reactive pulmonary hypertension after a switch operation. Successful treatment with glyceryl trinitrate.

Author

Damen, J and Hitchcock, J F

Abstract

After an arterial switch operation (anatomical correction for transposition of the great arteries) in a 6 month old child reactive pulmonary hypertension developed six hours after cardiopulmonary bypass. Intravenous glyceryl trinitrate was the only means by which the pulmonary hypertension could be reversed. [ABSTRACT FROM PUBLISHER]

Published
1985
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260. The SH2-containing inositol-5'-phosphatase enhances LFA-1-mediated cell adhesion and defines two signaling pathways for LFA-1 activation

Author

Rey-Ladino, J. A., Huber, M., Liu, L., Damen, J. E., Krystal, G., and Fumio Takei

Subjects
Immunology, Hematopoietic Stem Cells, Intercellular Adhesion Molecule-1, Lymphocyte Function-Associated Antigen-1, Phosphoric Monoester Hydrolases, Rats, src Homology Domains, Mice, Phosphatidylinositol 3-Kinases, Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases, Calcium-Calmodulin-Dependent Protein Kinases, Cell Adhesion, Immunology and Allergy, Animals, Tetradecanoylphorbol Acetate, Interleukin-3, Erythropoietin, Protein Kinase C, Protein Binding, Signal Transduction
Abstract

The inside-out signaling involved in the activation of LFA-1-mediated cell adhesion is still poorly understood. Here we examined the role of the SH2-containing inositol phosphatase (SHIP), a major negative regulator of intracellular signaling, in this process. Wild-type SHIP and a phosphatase-deficient mutant SHIP were overexpressed in the murine myeloid cell line, DA-ER, and the effects on LFA-1-mediated cell adhesion to ICAM-1 (CD54) were tested. Overexpression of wild-type SHIP significantly enhanced cell adhesion to immobilized ICAM-1, and PMA, IL-3, or erythropoietin further augmented this adhesion. In contrast, phosphatase dead SHIP had no enhancing effects. Furthermore, PMA-induced activation of LFA-1 on DA-ER cells overexpressing wild-type SHIP was dependent on protein kinase C but independent of mitogen-activated protein kinase activation, whereas cytokine-induced activation was independent of protein kinase C and mitogen-activated protein kinase activation but required phosphatidylinositol-3 kinase activation. These results suggest that SHIP may regulate two distinct inside-out signaling pathways and that the phosphatase activity of SHIP is essential for both of them.

262. The Growth of Oxide Single Crystals

Author

Robertson, J. M., primary, Damen, J. P. M., additional, Jonker, H. D., additional, van Hout, M. J. G., additional, Kamminga, W., additional, and Voermans, A. B., additional

Published
1974
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272. C1Esterase-Inhibitor Concentrate Prevents Hypotension from Plasma-Protein Solutions

Author

Brummelhuis H, Damen J, van der Starre P, and Sinclair D

Subjects
Complement Activating Enzymes, business.industry, Transfusion Reaction, Blood Proteins, General Medicine, Complement C1 Inactivator Proteins, Middle Aged, Bradykinin, Blood proteins, C1 esterase, Text mining, Biochemistry, Humans, Medicine, Hypotension, business, Aged
Published
1979

274. Comparative analysis of four methods to extract DNA from paraffin-embedded tissues: effect on downstream molecular applications

Author

Savelkoul Paul HM, van der Linden Johannes C, Damen Jan, Huijsmans Cornelis JJ, and Hermans Mirjam HA

Subjects
Medicine, Biology (General), QH301-705.5, Science (General), Q1-390
Abstract

Abstract Background A large portion of tissues stored worldwide for diagnostic purposes is formalin-fixed and paraffin-embedded (FFPE). These FFPE-archived tissues are an extremely valuable source for retrospective (genetic) studies. These include mutation screening in cancer-critical genes as well as pathogen detection. In this study we evaluated the impact of several widely used DNA extraction methods on the quality of molecular diagnostics on FFPE tissues. Findings We compared 4 DNA extraction methods from 4 identically processed FFPE mammary-, prostate-, colon- and lung tissues with regard to PCR inhibition, real time SNP detection and amplifiable fragment size. The extraction methods, with and without proteinase K pre-treatment, tested were: 1) heat-treatment, 2) QIAamp DNA-blood-mini-kit, 3) EasyMAG NucliSens and 4) Gentra Capture-Column-kit. Amplifiable DNA fragment size was assessed by multiplexed 200-400-600 bp PCR and appeared highly influenced by the extraction method used. Proteinase K pre-treatment was a prerequisite for proper purification of DNA from FFPE. Extractions with QIAamp, EasyMAG and heat-treatment were found suitable for amplification of fragments up to 400 bp from all tissues, 600 bp amplification was marginally successful (best was QIAamp). QIAamp and EasyMAG extracts were found suitable for downstream real time SNP detection. Gentra extraction was unsuitable. Hands-on time was lowest for heat-treatment, followed by EasyMAG. Conclusions We conclude that the extraction method plays an important role with regard to performance in downstream molecular applications.

Published
2010
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275. De anatomie van de buik en buikorganen

Author

Valke, L. L. F. G., Gerhardus, M. J. T., Claessen, R. J. M., Duitscher-Fransen, K., Moll van Charante, E. P., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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276. De longen en luchtwegen

Author

Vonk Noordegraaf-Roseboom, G., Crombag, L. M. M. J., Willems, L. N. A., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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277. De mammae en oksels

Author

Zeestraten, E. C. M., van Breukelen, A. J. E., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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278. De oren

Author

Smit, A. L., Gruintjes, F. W. G., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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279. De mond(holte)

Author

van Wijck-Warnaar, A., Gruintjes, F. W. G., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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280. Het neurologisch onderzoek

Author

Steenis, M., Odekerken, V. J. J., Ketels, M. M. A., Dijcks, R., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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281. Het Mentale Status Onderzoek (MSO)

Author

Smeets, M. J., Domen, P. A. E., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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282. De vrouwelijke genitaliën

Author

Hageraats, E., Gijsen, A. P., Urbach, S. F., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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283. De arteriële en veneuze circulatie

Author

van den Dungen, J. J. A. M., Fourneau, I. A. M., Bloemendaal, P. M., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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284. De anus en het rectum

Author

Valke, L. L. F. G., Claessen, R. J. M., Gerhardus, M. J. T., Duitscher-Fransen, K., Moll van Charante, E. P., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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285. De mannelijke genitaliën

Author

Ronkes, B. L., Meißner, A., Ebels, K. E., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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286. Het buikonderzoek op indicatie

Author

Claessen, R. J. M., Valke, L. L. F. G., Gerhardus, M. J. T., Duitscher-Fransen, K., Moll van Charante, E. P., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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287. De liezen

Author

Valke, L. L. F. G., Gerhardus, M. J. T., Claessen, R. J. M., Duitscher-Fransen, K., Moll van Charante, E. P., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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288. Het oriënterend buikonderzoek

Author

Gerhardus, M. J. T., Claessen, R. J. M., Valke, L. L. F. G., Duitscher-Fransen, K., Moll van Charante, E. P., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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289. Het hart

Author

van Veen, E. L., Al-Itejawi, H. H. M., Vanaeken, M., Iwema, J., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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290. Anatomie van de thorax

Author

Al-Itejawi, H. H. M., van Veen, E. L., Vanaeken, M., Iwema, J., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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291. De schedel en het gelaat

Author

de Rozario, L., Gruintjes, F. W. G., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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292. De hals

Author

Rijken, J. A., Gruintjes, F. W. G., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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293. De neus en neusbijholten

Author

van Wijck-Warnaar, A., Gruintjes, F. W. G., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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294. De ogen

Author

van Leeuwen, R., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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295. De huid en lymfeklieren

Author

Eekhof, J. A. H., Claessen, R. J. M., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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296. De algemene indruk

Author

Eekhof, J. A. H., Claessen, R. J. M., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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297. De kwetsbare oudere patiënt

Author

Hegge, H. H. M., Franssen, R., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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299. Het kind

Author

Doedens, R. A., Postma, A., Pierik, L. J. W. M., Kingma, A., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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300. De pasgeborene

Author

Oren, A., Thys, E., Kerstjens, J. M., de Jongh, T.O.H., editor, Jongen-Hermus, F.J., editor, Damen, J., editor, Daelmans, H.E.M., editor, Franssen, R., editor, de Klerk-van der Wiel, I., editor, Pieterse, A.D., editor, Schouwenberg, B.J.J.W., editor, and Schuring, F., editor

Published
2022
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