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2,555 results on '"Chen Guo-qiang"'

260. Mechanism of Reduced Muscle Atrophy via Ketone Body (D)-3-Hydroxybutyrate

Author

Chen, Jin, primary, Li, Zihua, additional, Zhang, Yudian, additional, Zhang, Xu, additional, Zhang, Shujie, additional, Liu, Zonghan, additional, Yuan, Huimei, additional, Pang, Xiangsheng, additional, Liu, Yaxuan, additional, Tao, Wuchen, additional, CHEN, Xiaoping, additional, ZHANG, Peng, additional, and Chen, Guo-Qiang, additional

Published
2022
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273. Dose–response relationship between dietary inflammatory index and diabetic kidney disease in US adults.

Author

Wang, Yong-Jun, Du, Yang, Chen, Guo-Qiang, Cheng, Zhen-Qian, Liu, Xue-Mei, and Lian, Ying

Subjects
DIABETIC nephropathies, HEALTH & Nutrition Examination Survey, GLOMERULAR filtration rate
Abstract

Objective: The impact of the dietary potential inflammatory effect on diabetic kidney disease (DKD) has not been adequately investigated. The present study aimed to explore the association between dietary inflammatory index (DII) and DKD in US adults. Design: This is a cross-sectional study. Setting: Data from the National Health and Nutrition Examination Survey (2007–2016) were used. DII was calculated from 24-h dietary recall interviews. DKD was defined as diabetes with albuminuria, impaired glomerular filtration rate or both. Logistic regression and restricted cubic spline models were adopted to evaluate the associations. Participants: Data from the National Health and Nutrition Examination Survey (2007–2016) were used, which can provide the information of participants. Results: Four thousand two-hundred and sixty-four participants were included in this study. The adjusted OR of DKD was 1·04 (95 % CI 0·81, 1·36) for quartile 2, 1·24 (95 % CI 0·97, 1·59) for quartile 3 and 1·64 (95 % CI 1·24, 2·17) for quartile 4, respectively, compared with the quartile 1 of DII. A linear dose–response pattern was observed between DII and DKD (P nonlinearity = 0·73). In the stratified analyses, the OR for quartile 4 of DII were significant among adults with higher educational level (OR 1·83, 95 % CI 1·26, 2·66) and overweight or obese participants (OR 1·67, 95 % CI 1·23, 2·28), but not among the corresponding another subgroup. The interaction effects between DII and stratified factors on DKD were not statistically significant (all P values for interactions were >0·05). Conclusions: Our findings suggest that a pro-inflammatory diet, shown by a higher DII score, is associated with increased odd of DKD. [ABSTRACT FROM AUTHOR]

Published
2023
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274. Co‐production of biofuel, bioplastics and biochemicals during extended fermentation of Halomonas bluephagenesis.

Author

Park, Helen, Toogood, Helen S., Chen, Guo‐Qiang, and Scrutton, Nigel S.

Subjects
POLY-beta-hydroxybutyrate, BIODEGRADABLE plastics, FERMENTATION, BIOMASS energy, PROPANE as fuel, PRODUCT costing, FATTY acids
Abstract

Halomonas bluephagenesis TD1.0 was engineered to produce the biofuel propane, bioplastic poly‐3‐hydroxybutyrate (PHB), and biochemicals mandelate and hydroxymandelate in a single, semi‐continuous batch fermentation under non‐sterile conditions. Multi‐product separation was achieved by segregation of the headspace gas (propane), fermentation broth ([hydroxy]mandelate) and cellular biomass (PHB). Engineering was performed by incorporating the genes encoding fatty acid photodecarboxylase (CvFAP) and hydroxymandelic acid synthase (SyHMAS) into a H. bluephagenesis hmgCAB cassette knockout to channel flux towards (hydroxy)mandelate. Design of Experiment strategies were coupled with fermentation trials to simultaneously optimize each product. Propane and mandelate titres were the highest reported for H. bluephagenesis (62 g/gDCW and 71 ± 10 mg/L respectively) with PHB titres (69% g/gDCW) comparable to other published studies. This proof‐of‐concept achievement of four easily separated products within one fermentation is a novel achievement probing the versatility of biotechnology, further elevating H. bluephagenesis as a Next Generation Industrial Biotechnology (NGIB) chassis by producing highly valued products at a reduced cost. [ABSTRACT FROM AUTHOR]

Published
2023
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278. List of Contributors

Author

Alén, Raimo, primary, Anusree, Murali, additional, Baigori, Mario D., additional, Binod, Parameswaran, additional, Capaz, Rafael Silva, additional, Castro, Guillermo R., additional, Caullet, Coraline, additional, Cerqueira, Miguel Ângelo, additional, Chen, Guo-Qiang, additional, Chen, Jian, additional, de Jong, Ed, additional, de Wild, Paul J., additional, Dombrowski, Lilli, additional, Du, Guocheng, additional, Frauz, Bettina, additional, Giri, Balendu S., additional, Goswami, Mandavi, additional, Gottumukkala, Lalitha Devi, additional, Höfer, Rainer, additional, Jungmeier, Gerfried, additional, Kambourova, Margarita, additional, Kashdan, Tyler, additional, Körner, Ina, additional, Kröger, Michael, additional, Le Nôtre, Jérôme, additional, Liang, Quanfeng, additional, Liang, Yanna, additional, Lindorfer, Harald, additional, Liu, Long, additional, Nampoothiri, K. Madhavan, additional, Nobre, Clarisse, additional, Nogueira, Luiz Augusto Horta, additional, Oner, E. Toksoy, additional, Pandey, Ashok, additional, Patel, Anil K., additional, Pera, Licia M., additional, Petrick, Ingolf, additional, Poli, Annarita, additional, Qi, Qingsheng, additional, Rodrigues, Lígia Raquel, additional, Sajna, Kuttuvan Valappil, additional, Sindhu, Raveendran, additional, Singhania, Reeta R., additional, Sterner, Christy, additional, Sukumaran, Rajeev K., additional, Teixeira, José António, additional, Thomas, Leya, additional, Vicente, António Augusto, additional, Wang, Ying, additional, and Zhang, Juanyu, additional

Published
2015
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