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PURPOSE To assess the technical success and complications of Angio-Seal vascular closure device in antegrade common femoral artery (CFA) punctures. METHODS Over a 14-month period, 55 patients (37 men; age range 37-94 years) underwent antegrade CFA Angio-Seal placement at a single center; the clinical data and angiograms were reviewed retrospectively. A total of 56 antegrade CFA punctures were made for hemostasis; 6-F Angio-Seal devices (40 model STS and 12 model VIP) were deployed in 52 CFAs, and 8-F Angio-Seal devices were deployed in 4. RESULTS The technical success rate was 98.2% (55/56). Two (3.6%) patients developed small, non-expanding hematomas (

The nasal commensal bacterium Staphylococcus lugdunensis produces a novel cyclic peptide antibiotic, lugdunin, that inhibits colonization by S. aureus in animal models and is associated with a significantly reduced S. aureus carriage rate in humans, suggesting that human commensal bacteria could be a valuable resource for the discovery of new antibiotics. The vast majority of systemic bacterial infections are caused by facultative, often antibiotic-resistant, pathogens colonizing human body surfaces. Nasal carriage of Staphylococcus aureus predisposes to invasive infection, but the mechanisms that permit or interfere with pathogen colonization are largely unknown. Whereas soil microbes are known to compete by production of antibiotics, such processes have rarely been reported for human microbiota. We show that nasal Staphylococcus lugdunensis strains produce lugdunin, a novel thiazolidine-containing cyclic peptide antibiotic that prohibits colonization by S. aureus, and a rare example of a non-ribosomally synthesized bioactive compound from human-associated bacteria. Lugdunin is bactericidal against major pathogens, effective in animal models, and not prone to causing development of resistance in S. aureus. Notably, human nasal colonization by S. lugdunensis was associated with a significantly reduced S. aureus carriage rate, suggesting that lugdunin or lugdunin-producing commensal bacteria could be valuable for preventing staphylococcal infections. Moreover, human microbiota should be considered as a source for new antibiotics. The majority of systemic bacterial infections are caused by endogenous pathogens from human microbiota, and the opportunistic pathogen Staphylococcus aureus, commonly found in the external opening of the nostrils, is one of the most clinically important because of the prevalence of multi-drug resistant strains. The mechanisms that permit or interfere with pathogen colonization have remained unclear. This study shows that S. lugdunensis, a commensal bacterium that shares the nasal niche with S. aureus and is associated with a reduced S. aureus carriage rate in humans, produces a novel cyclic peptide antibiotic (lugdunin) that inhibits colonization by S. aureus in animal models. Lugdunin is bactericidal against major pathogens and not prone to causing development of resistance in S. aureus, suggesting that lugdunin or lugdunin-producing commensals could be valuable for preventing staphylococcal infections.

In this paper a generic approach to the SLAM (Simultaneous Localization and Mapping) problem is proposed. The approach is based on a probabilistic SLAM algorithm and employs only two portable sensors, an inertial measurement unit (IMU) and a laser range finder (LRF) to estimate the state and environment of a robot. Scan-matching is applied to compensate for noisy IMU measurements. This approach does not require any robot-specific characteristics, e.g. wheel encoders or kinematic models. In principle, this minimal sensory setup can be mounted on different robot systems without major modifications to the underlying algorithms. The sensory setup with the probabilistic algorithm is tested in real-world experiments on two different kinds of robots: a simple two-wheeled robot and the six-legged hexapod AMOSII. The obtained results indicate a successful implementation of the approach and confirm its generic nature. On both robots, the SLAM problem can be solved with reasonable accuracy.

To compare the clinical characteristics of a population of patients with divergence insufficiency in the absence of associated neurologic disease to those patients with divergence insufficiency and an associated neurologic disorder.A retrospective review of 251 patients diagnosed with divergence insufficiency and/or divergence paralysis. Clinical features include the age at onset, fusional divergence amplitudes, the size of the esodeviation, treatment offered, and the presence or absence of associated neurologic conditions. Classification into primary and secondary divergence insufficiency solely depended on the absence or presence of neurologic disorders, respectively.The incidence of neurologic disease associated with divergence insufficiency was 17%. The average age at onset was 62 years for primary and 51 years for secondary divergence insufficiency. Nystagmus was noted in 43% of secondary divergence insufficiency patients and 0.01% of primary divergence insufficiency patients. Both groups exhibited decreased fusional divergence at distance fixation while retaining normal fusional divergence at near.The majority of patients were classified as primary divergence insufficiency. Though this form of divergence insufficiency is neurologically benign, it may easily mask a more severe neurologic condition for which the presenting symptom is also diplopia for distance viewing only. These results show the importance of obtaining a detailed history regarding the symptoms, as well as documenting neurologic signs, particularly nystagmus, when investigating divergence insufficiency.

Zusammenfassung Autonome Fahrzeuge und hegemoniale Mannlichkeit Anhand der Analyse des Diskurses in deutschen Online-Medien uber autonome Fahrzeuge zeigt Anna-Lena Berscheid, inwiefern diese eine Gefahr fur das Auto als Symbol hegemonialer Mannlichkeit darstellen konnen. Das Auto dient bislang als wirkmachtiges Mittel zur Performativitat von Mannlichkeit, etwa durch das Fahren mit hoher Geschwindigkeit, risikoreiche Manover, aber auch durch den Ausdruck der eigenen Macht oder Flexibilitat. An diesem Symbol wird nun durch die „„neutrale“ Fahrweise eines automatisierten Steuerungscomputers geruttelt. Der Artikel zeigt auf, dass der Diskurs uber autonome Fahrzeuge voller Widerspruche steckt: Einerseits wird der Mensch von den Diskurs-AkteurInnen als nicht mehr verantwortbares Sicherheitsrisiko konstruiert, der seine Steuergewalt an den Computer abgeben soll und damit zum Passagier wird. Andererseits wird oftmals ausgepragtes Misstrauen in die Technologie und ihre Zuverlassigkeit zum Ausdruck gebracht und von vielen Diskurs-AkteurInnen betont, dass sie auf den „Fahrspas” nicht verzichten mochten. Ironischerweise entsprechen Momente des „Fahrspases“ jenem risikoreichen und als stereotyp mannlich konnotiertem Fahrverhalten, welches eigentlich durch den Einsatz des Computers neutralisiert werden soll. Um diese Angste und Bedurfnisse aufzugreifen, scheint die Auto-Branche die Einfuhrung eines vollautomatisierten Fahrzeugs gar nicht zu verfolgen, sondern fokussiert auf sogenannte Fahrassistenzsysteme, die ausschaltbar sind und den/die FahrerIn lediglich unterstutzen, aber nicht vollstandig aus der Verantwortung nehmen. ----- Autonomous Cars and Hegemonic Masculinity Abstract Analyzing the German media discourse on autonomous cars, Anna-Lena Berscheid shows how the invention of autonomous cars might undermine the car as a symbol of hegemonic masculinity. An autonomous car would eliminate crucial characteristics usually used to perform masculinity, such as speeding, risk-taking, flexibility or expressing individual power. The analysis illustrates contradictory discourses on autonomous cars: On the one hand, it is argued that this new form of (auto)mobility improves street security by transferring responsibility to the computer and turning the human driver into a passenger. This discourse fosters the idea of a „neutral” and therefore safer driving-style. On the other hand, discourse actors claim that they cannot fully trust technology and therefore, they aim to maintain those factors of driving (a car) which are considered as „fun”. Ironically, the concept of „fun” implies stereotyped „masculinity” and therefore often includes dangerous driving characteristics that are meant to get „neutralized” by the autonomous car. These contradictions show that the automobile industry hesitates to give up the car as a means to express masculinity. That might be the reason why the car industry focuses on so called driving assistance systems which are supposed to support the driver, but leave him/her in control of the car as such. ----- Bibliographie: Berscheid, Anna-Lena: Autonome Fahrzeuge und hegemoniale Mannlichkeit in der Automobilkultur, Femina Politica, 2-2014, S. 22-34. https://doi.org/10.3224/feminapolitica.v23i2.17611

High power pulsed magnetron sputtering (HPPMS) plasmas are pulsed discharges where the plasma composition as well as the fluxes and energies of ions are changing during the pulse. The time resolved energy distribution for Ar$^{1+}$ ions was measured and Phase Resolved Optical Emission Spectroscopy (PROES) for the Ar I line at 760 nm was done to get more insight in the transport properties of the plasma forming noble gas. These measurements were performed during HPPMS of titanium with argon at 0.5 Pa. The peak power density during the 50 $\mu$s pulses was 1.8 kW/cm$^2$. In this contribution we demonstrate how time resolved mass spectrometry and ICCD cameras can be used to shed more light on energy and particle transport in HPPMS-plasmas., Comment: The manuscript was submitted to the 7th Triennial Special Issue of the IEEE Transactions on Plasma Science "Images in Plasma Science," scheduled for publication in September 2014. The manuscript length is limited to 2 pages!

This is a case report describing a rare cause of massive duodenal ulcer hemorrhage resulting from the erosion of the supraduodenal branch of the left hepatic artery. This arterial branch is not a well known variation and is rarely recognized as a source of duodenal bleeding.

This article presents self-report scales for the assessment of perceived dependency and insecurity in a romantic relationship. These scales were originally developed many years ago (Fei & Berscheid, 1977) but were never published. The process of original scale development is summarized, and results from five studies (total N = 1,283; including data from the original Fei & Berscheid studies) are presented showing evidence for (a) scale reliability and validity; (b) the association between dependency and insecurity and the relationship conditions that moderate this association; (c) the association of dependency and insecurity with other theoretically relevant dimensions of close relationships; and (d) dyadic-level issues of partner similarity and correlates of discrepancies in levels of dependency and insecurity. The results indicate that the two scales are reliable, valid, and associated with many other relationship constructs (e.g., commitment, love, closeness, and attachment). Believing that dependency and insecurity are fundamental dimensions underlying romantic relationships, two decades ago Fei and Berscheid constructed two scales to assess these properties of relationships. Al

The terms love and in love are often used in common discourse. A social categorical approach, whereby the actual members of an individual's social categories are examined, was used to investigate the differential meaning of these terms. It was hypothesized that (a) the membership of the love category would be larger than that of the in love category; (b) the membership of the in love category would be encapsulated within the love category membership, indicating that love is the higher order generic term; (c) that the membership of the in love category, but not the love category, would be encapsulated within a sexual attraction/desire category membership; (d) although these effects would be observed for both men and women, certain gender differences would be observed. All hypotheses were confirmed. The implications of these findings for a taxonomy of love as well as for understanding and predicting love phenomena are discussed.

Only recently have researchers recognized that the qualities that are considered desirable in a short-term sexual partner may differ from those sought in a long-term marriage partner. To investigate this hypothesis, and to explore gender differences in what are considered to be sexually as opposed to maritally desirable characteristics, 70 men and women ranked a set of 23 characteristics in terms of desirability in a potential sexual and marriage partner. As hypothesized, results revealed that both men and women preferred a physically attractive potential sexual partner, and women showed no more preference than did men for a socially or financially powerful potential sexual partner. Also as predicted, men more than women preferred a physically attractive marriage partner; unexpectedly, women did not find such characteristics as social or financial power and a college degree as more desirable in a prospective spouse than did men.

Although scholars' interest in love phenomena has continued to increase in recent years, a common conceptual language for the study of love has not yet emerged, as is evidenced by the large number of love taxonomies and associated vocabularies that have been advocated. A promising avenue for the development of a common scientific vocabulary of love lies in the systematic examination of the love vocabularies of laypersons to identify what varieties of love, if any, their lexicon reflects. Several means by which love researchers have attempted such examinations are described and illustrated with reference to the linguistic expressions “love” and “in love.” These methods include direct questioning, autobiographical reports, inferential studies, and the prototype approach, which introduces the probabilistic view of cognitive categorization structure and process to the study of love. Several of the underlying assumptions of the prototype approach are discussed and contrasted to those of the social categorical approach we present here. The social categorical method is described in this approach, respondents place persons in their actual social worlds into social categories, and the associations among the memberships of those categories are examined. Finally, the implications of some of the findings derived from this method for a taxonomy of love and for the study of interpersonal relationships are discussed.

Little is known about the beliefs men and women have about the causes of sexual desire, despite the interpersonal and individual significance of those beliefs. Participants in this study received a definition of sexual desire and answered a set of free-response questions exploring their beliefs about the causal antecedents of male and female sexual desire. The results indicated that more women than men view female (and male) sexual desire as caused by external factors. In addition, both men and women believe that male and female sexual desire have different causes: intraindividual and erotic environmental factors are believed to cause male sexual desire, but interpersonal and romantic environmental factors are believed to cause female sexual desire. Although both men and women view physical attractiveness and overall personality as sexually desirable male and female characteristics, women, but not men, view femininity as a sexually desirable female characteristic, and men, but not women, view social and financial power or status as a sexually desirable male attribute.

Knowledge about interpersonal relationships is currently encapsulated within type of relationship (e.g. romantic, parental), with relationship type confounded with disciplinary approach, with the characteristics of the partners usually found in that type of relationship, as well as with the nature of the relationship phenomena examined. It is argued that a critical issue for the relationship field is whether a grand, overarching theory of relationships can be developed. Such a theory would directly address the principal relationship types, delineating the similarities and differences among them with respect to the causal conditions associated with various relationship phenomena. It is further argued that an important class of causal conditions that governs behavior in all relationships is the culturally defined norms, roles and expectations associated with type of relationship, and that these cultural prescriptions - as opposed to `individualistic' causal conditions - must play an important role in any unifying theory. If so, the sociological and anthropological perspectives need to achieve better balance with the psychological perspective that is becoming dominant in theory and research on interpersonal relationships.

This study investigated whether longitudinal predictions of stability are improved when assessments of the relationship are obtained from both members of the couple rather than just from 1 partner and, if so, which partner's assessments are the most diagnostic of stability. Both partners in 120 dating couples provided self-report assessments on 16 relationship dimensions, and 6 months later 2 outcomes were examined: stability and emotional distress if breakup had occurred. Assessments from both partners were more predictive of stability than were assessments from 1 (randomly chosen) partner, but the improvement was small. Assessments from female partners were no more predictive of stability than were those from male partners. However, assessments from "weak-link" partners (whose standing on stability indicators was lower than the other member of the couple) were significantly more diagnostic of stability than were those from "strong-link" partners. These and other findings are discussed. The identification of factors that contribute to the stability of a relationship has been of continuing theoretical and empirical concern to relationship researchers. Some indication of the central role that the prediction of relationship stability has played in relationship theory and research is provided by the sheer number of variables that have been theoretically proposed and empirically shown to predict the stability of relationships in general and of romantic relationships in particular (for a review, see Surra, 1990). The stability of an individual's premarital, romantic relationship, for example, has been associated with the individual's initial report of: greater investment in the relationship (Felmlee, Sprecher, & Bassin, 1990; Hendrick, Hendrick, & Adler, 1988; Lund, 1985,Rusbult, 1983);greater commitment to maintaining the relationship (Hendrick et al., 1988; Lund, 1985; Rusbult, 1983); greater love for the partner (Berg & McQuinn, 1986; Lund, 1985; Rubin, Peplau, & Hill, 1981); more time spent together with the partner (Berscheid, Snyder, & Omoto, 1989; Simpson, 1987; Felmlee etal., 1990); greater diversity of activities performed with the partner (Berscheid et al., 1989; Simpson, 1987; Surra & Longstreth, 1990); greater strength of

Nature 535, 511–516 (2016); doi:10.1038/nature18634 In the interests of transparency, in this Article we wish to amend the competing financial interests statement to read: “Tuebingen University has filed a provisional patent application that covers the compound lugdunin and derivatives thereof, as well as the application of lugdunin-producing bacteria for the prevention of bacterial infections (European patent application number EP 15 160 285.

The increasing emergence of multidrug-resistant Staphylococcus aureus is a problem of global importance. Here, we report the genome of S. aureus VC40, which is resistant to the last-resort antibiotics vancomycin and daptomycin. Its genome sequence will allow insights into the mechanisms that convey full resistance to these compounds.

Diese Arbeit beschäftigt sich mit der Frage, inwiefern Lady Gagas Performance hinsicht-lich ihres queer-feministischen bzw. emanzipatorischen Potenzials gelesen werden kann. Zur Beantwortung wird eine mehrstufige Analyse dreier Videoclips Lady Gagas nach einer neuartigen Methode der Autorinnen Martina Schuegraf und Sandra Smykalla durchge-führt. Die Interpretation bzw. Lesart des Analysematerials orientiert sich dabei zum einen am Forschungsstand zur Darstellung von Geschlecht und Sexualität im Videoclip bzw. zu Madonna. Zum anderen basiert die Interpretation auf sogenannten sensitizing concepts; dies sind theoretische Konzepte, die den Fokus der Analyse bestimmen. Die Analyse setzt sich aus mehreren deskriptiven bzw. kontextualisierenden Teilen zu-sammen, an deren Ende die Interpretation anhand der sensitizing concepts steht. Analy-siert werden die Videos zu Love Game, Telephone sowie Alejandro. Diese Wahl erfolgte, da die Videos zum einen eine zeitliche Entwicklung der Performance Lady Gagas, zum anderen aber auch deren Vielfalt aufzeigen. Ergebnis der Interpretation ist, dass Lady Gaga zwar nicht als klassisch feministisch be-zeichnet werden kann (und sich selbst auch nicht so bezeichnen möchte). Gleichzeitig weisen ihre Videos jedoch verschiedene emanzipatorische Elemente auf, darunter die offene Darstellung von Homosexualität und Homoerotik, die Selbstdarstellung der Künst-lerin als eigenständige Frau, female solidarity sowie das Spiel mit alltäglichem Wissen über Geschlecht bzw. geschlechtstypischem Verhalten. Ziel dieser Arbeit ist es, das gesellschaftliche Potenzial eines Pop-Phänomens wie Lady Gaga aufzuzeigen. Jedoch verbleibt die Analyse auf einer reinen Interpretationsebene, sodass über die tatsächlichen Auswirkungen der Videoclips bislang nur spekuliert werden kann.

Plug-in hybrid electric vehicles (PHEVs) are an environmentally friendly technology that is expected to rapidly penetrate the transportation system. Renewable energy sources such as wind and solar have received considerable attention as clean power options for future generation expansion. However, these sources are intermittent and increase the uncertainty in the ability to generate power. The deployment of PHEVs in a vehicle-to-grid (V2G) system provide a potential mechanism for reducing the variability of renewable energy sources. For example, PHEV supporting infrastructures like battery exchange stations that provide battery service to PHEV customers could be used as storage devices to stabilize the grid when renewable energy production is fluctuating. In this paper, we study how to best site these stations in terms of how they can support both the transportation system and the power grid. To model this problem we develop a two-stage stochastic program to optimally locate the stations prior to the realization of battery demands, loads, and generation capacity of renewable power sources. We develop two test cases to study the benefits and the performance of these systems., Submitted to IEEE-SmartGridComm2010

The current electric power grid is a result of incremental growth over the past 100 years under assumptions that a grid provides reliable and controllable generation of energy cheaply and with limited environmental impact. Moving into the twenty-first century, many of these assumptions will no longer hold; the existing grid is ill-equipped to handle the new requirements that it is being subjected to. This paper presents a novel hybridization algorithm to upgrade the existing electric power network to feasibly achieve future renewable energy generation goals. The algorithm was integrated with state-of-the-art electric power analysis approaches to produce feasible transmission networks to accommodate 20% wind power by 2030 goals.

Concave Triphenylmethane Dyestuffs Triply- and doubly-bridged as well as dye molecules (2, 18, and 11) connected by a single chain were prepared including the corresponding phenolphthalein and fluorescein derivatives (24a–c). The concave orange-coloured triphenylmethane dye 2 exhibits solvatochromic and halochromic effects different to nonmacrocyclic reference substances. The triphenylmethane dyes are reversibly transferred to the corresponding uncoloured macrocycles by changing the pH. The structures of 9, 22b, and 22c were confirmed by X-ray analyses.

This article, an expansion of remarks originally made on the occasion of the 25th anniversary of the Society of Experimental Social Psychology in October of 1990, presents a selective and informal retrospective on the rapid growth of social psychology from a discipline uncertain of its identity and future 25 years ago to the robust field it is today. The entry of women into the field, the cumulative nature of the growth of social psychological theory and research, as well as the expansion of social psychology's basic and applied research boundaries are highlighted

Multiple-Bridged Triphenylmethanes Up to fourfold-bridged macrocyclic compounds bearing triphenylmethane units which form a large molecular cavity were prepared for the first time. The macrobicyclus 4 crystallizes from acetonitrile as 1:1 adduct and from phenylacetonitrile as 1:3 adduct with the respective solvent. The X-ray structures of these complexes are compared with the related 1:5 adduct of 13 with benzene.

A triply bridged triphenylmethyl dication {6,13,23,30,39,46-hexaoxaoctacyclo[16.16.16.2 2,5 .2 14,17 .2 19,22 .2 31,38 .2 47,50 ]dohexaconta-2,4,14,16,19,21,31,33,35,37,47,49,51,53,55,57,59,61-octadecaene-8,10,25,27,41,43-hexayne-1,18-diyliumbis(tetrafluoroborate) 4} and its open-chained analogue are synthesized by using a new variant of the Eglinton reaction

It was found that rhodosaminylanthraclinone-type anthracyclines are readily N-mono-demethylated upon irradiation with visible light, leading to 3′-N-methyl-α-L-daunosarninylanthracyclinones in good yields. The reaction is preferentially observed with rhodosaminylanthracyclinones in which OH-4′ of the sugar (rhodosamine) moiety is not further glycosylated. 3′-N-methyl-α-L-daunosaminyl anthracyclinones provide key compounds that can readily be further derivatized.