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251. A spectroscopic thermometer: individual vibrational band spectroscopy with the example of OH in the atmosphere of WASP-33b

Author

Wright, Sam O. M., Nugroho, Stevanus K., Brogi, Matteo, Gibson, Neale P., de Mooij, Ernst J. W., Waldmann, Ingo, Tennyson, Jonathan, Kawahara, Hajime, Kuzuhara, Masayuki, Hirano, Teruyuki, Kotani, Takayuki, Kawashima, Yui, Masuda, Kento, Birkby, Jayne L., Watson, Chris A., Tamura, Motohide, Zwintz, Konstanze, Harakawa, Hiroki, Kudo, Tomoyuki, Hodapp, Klaus, Jacobson, Shane, Konishi, Mihoko, Kurokawa, Takashi, Nishikawa, Jun, Omiya, Masashi, Serizawa, Takuma, Ueda, Akitoshi, Vievard, Sébastien, and Yurchenko, Sergei N.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

Individual vibrational band spectroscopy presents an opportunity to examine exoplanet atmospheres in detail by distinguishing where the vibrational state populations of molecules differ from the current assumption of a Boltzmann distribution. Here, retrieving vibrational bands of OH in exoplanet atmospheres is explored using the hot Jupiter WASP-33b as an example. We simulate low-resolution spectroscopic data for observations with the JWST's NIRSpec instrument and use high resolution observational data obtained from the Subaru InfraRed Doppler instrument (IRD). Vibrational band-specific OH cross section sets are constructed and used in retrievals on the (simulated) low and (real) high resolution data. Low resolution observations are simulated for two WASP-33b emission scenarios: under the assumption of local thermal equilibrium (LTE) and a toy non-LTE model for vibrational excitation of selected bands. We show that mixing ratios for individual bands can be retrieved with sufficient precision to allow the vibrational population distributions of the forward models to be reconstructed. A simple fit for the Boltzmann distribution in the LTE case shows that the vibrational temperature is recoverable in this manner. For high resolution, cross-correlation applications, we apply the individual vibrational band analysis to an IRD spectrum of WASP-33b, applying an 'un-peeling' technique. Individual detection significances for the two strongest bands are shown to be in line with Boltzmann distributed vibrational state populations consistent with the effective temperature of the WASP-33b atmosphere reported previously. We show the viability of this approach for analysing the individual vibrational state populations behind observed and simulated spectra including reconstructing state population distributions., Comment: Submitted for publication in AJ

Published
2023
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252. Search for $CP$ violation in $D^{+}_{(s)}\rightarrow K^{+}K^{0}_{S}h^{+}h^{-}$ $(h=K,\pi)$ decays and observation of the Cabibbo-suppressed decay $D^{+}_{s}\rightarrow K^{+}K^{-}K^{0}_{S}\pi^{+}$

Author

Belle Collaboration, Moon, H. K., Won, E., Adachi, I., Aihara, H., Asner, D. M., Atmacan, H., Aulchenko, V., Aushev, T., Ayad, R., Babu, V., Bahinipati, S., Banerjee, Sw., Bauer, M., Behera, P., Belous, K., Bennett, J., Bessner, M., Bhardwaj, V., Bhuyan, B., Biswas, D., Bodrov, D., Borah, J., Bozek, A., Bračko, M., Branchini, P., Browder, T. E., Budano, A., Campajola, M., Červenkov, D., Chang, M. -C., Chekelian, V., Cheon, B. G., Chilikin, K., Cho, H. E., Cho, K., Choi, Y., Choudhury, S., Cinabro, D., Cochran, J., Das, S., Dash, N., De Nardo, G., De Pietro, G., Dhamija, R., Di Capua, F., Dingfelder, J., Doležal, Z., Dong, T. V., Dossett, D., Dubey, S., Epifanov, D., Ferber, T., Ferlewicz, D., Fulsom, B. G., Garg, R., Gaur, V., Giri, A., Goldenzweig, P., Graziani, E., Gu, T., Guan, Y., Gudkova, K., Halder, S., Hara, T., Hayasaka, K., Hayashii, H., Hedges, M. T., Herrmann, D., Hou, W. -S., Hsu, C. -L., Iijima, T., Inami, K., Inguglia, G., Ipsita, N., Ishikawa, A., Itoh, R., Iwasaki, M., Jacobs, W. W., Jang, E. -J., Jia, S., Jin, Y., Joo, K. K., Kaliyar, A. B., Kawasaki, T., Kiesling, C., Kim, C. H., Kim, D. Y., Kim, K. -H., Kim, Y. -K., Kinoshita, K., Kodyš, P., Konno, T., Korobov, A., Korpar, S., Kovalenko, E., Križan, P., Krokovny, P., Kuhr, T., Kumar, M., Kumar, R., Kumara, K., Kuzmin, A., Kwon, Y. -J., Lalwani, K., Lange, J. S., Lee, S. C., Li, J., Li, L. K., Li, Y., Libby, J., Lieret, K., Lin, Y. -R., Liventsev, D., Luo, T., Ma, Y., Masuda, M., Matsuda, T., Matvienko, D., Maurya, S. K., Merola, M., Metzner, F., Miyabayashi, K., Mizuk, R., Mohanty, G. B., Nakamura, I., Nakao, M., Nakazawa, H., Natochii, A., Nayak, L., Nisar, N. K., Nishida, S., Ogawa, K., Ogawa, S., Ono, H., Oskin, P., Pakhlov, P., Pakhlova, G., Pang, T., Pardi, S., Park, H., Park, J., Park, S. -H., Passeri, A., Paul, S., Pedlar, T. K., Pestotnik, R., Piilonen, L. E., Podobnik, T., Prencipe, E., Prim, M. T., Rabusov, A., Röhrken, M., Rostomyan, A., Rout, N., Russo, G., Sandilya, S., Santelj, L., Savinov, V., Schnell, G., Schwanda, C., Schwartz, A. J., Seino, Y., Senyo, K., Sevior, M. E., Shapkin, M., Sharma, C., Shen, C. P., Shiu, J. -G., Sokolov, A., Solovieva, E., Starič, M., Sumihama, M., Sumiyoshi, T., Takizawa, M., Tamponi, U., Tanida, K., Tenchini, F., Trabelsi, K., Uchida, M., Uglov, T., Unno, Y., Uno, K., Uno, S., Urquijo, P., Vahsen, S. E., van Tonder, R., Varner, G., Varvell, K. E., Vinokurova, A., Wang, D., Wang, M. -Z., Watanabe, M., Watanuki, S., Wiechczynski, J., Yabsley, B. D., Yan, W., Yang, S. B., Yelton, J., Yin, J. H., Yook, Y., Yuan, C. Z., Yuan, L., Yusa, Y., Zhai, Y., Zhang, Z. P., Zhilich, V., and Zhukova, V.

Subjects
High Energy Physics - Experiment
Abstract

We search for $CP$ violation by measuring a $T$-odd asymmetry in the Cabibbo-suppressed $D^{+}\rightarrow K^{+}K^{0}_{S}\pi^{+}\pi^{-} $ decay, and in the Cabibbo-favored $D^{+}_{s}\rightarrow K^{+}K^{0}_{S}\pi^{+}\pi^{-}$ and $D^{+}\rightarrow K^{+}K^{-}K^{0}_{S}\pi^{+}$ decays. We use 980 ${\rm fb}^{-1}$ of data collected by the Belle detector running at the KEKB asymmetric-energy $e^{+}e^{-}$ collider. The $C\!P$-violating $T$-odd parameter ${a}^{T\text{-}\rm{odd}}_{CP}$ is measured to be ${a}^{T\text{-}\rm{odd}}_{CP}(D^{+}\rightarrow K^{+}K^{0}_{S}\pi^{+}\pi^{-})=(0.34\pm0.87\pm0.32)\%,$ ${a}^{T\text{-}\rm{odd}}_{CP}(D^{+}_{s}\rightarrow K^{+}K^{0}_{S}\pi^{+}\pi^{-})=(-0.46\pm0.63\pm0.38)\%,$ and ${a}^{T\text{-}\rm{odd}}_{CP}(D^{+}\rightarrow K^{+}K^{-}K^{0}_{S}\pi^{+})=(-3.34\pm2.66\pm0.35)\%,$ where the first uncertainty is statistical and the second is systematic. We also report the first observation of the Cabibbo-suppressed decay $D^{+}_{s}\rightarrow K^{+}K^{-}K^{0}_{S}\pi^{+}$. The branching fraction is measured relative to that of the analogous Cabibbo-favored decay : $B(D^{+}_{s}\rightarrow K^{+}K^{-}K^{0}_{S}\pi^{+}) / B(D^{+}_{s}\rightarrow K^{+}K^{0}_{S}\pi^{+}\pi^{-}) = (1.36\pm 0.15\pm 0.04)\%$.

Published
2023
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253. Measurement of the $e^+e^- \to B_s^0 \bar{B}_s^0 X$ cross section in the energy range from $10.63$ to $11.02$ GeV using inclusive $D_s^{\pm}$ and $D^0$ production

Author

Belle Collaboration, Zhukova, V., Mizuk, R., Adachi, I., Aihara, H., Said, S. Al, Asner, D. M., Atmacan, H., Aulchenko, V., Aushev, T., Ayad, R., Babu, V., Banerjee, Sw., Bauer, M., Behera, P., Belous, K., Bennett, J., Bernlochner, F., Bessner, M., Bilka, T., Biswas, D., Bobrov, A., Bodrov, D., Bondar, A., Borah, J., Bozek, A., Bračko, M., Branchini, P., Browder, T. E., Campajola, M., Cao, L., Červenkov, D., Chang, M. -C., Cheon, B. G., Chilikin, K., Cho, H. E., Cho, K., Choi, S. -K., Choi, Y., Choudhury, S., Cinabro, D., Das, S., De Nardo, G., De Pietro, G., Dhamija, R., Di Capua, F., Dong, T. V., Dubey, S., Ecker, P., Epifanov, D., Ferber, T., Ferlewicz, D., Fulsom, B. G., Gaur, V., Garmash, A., Giri, A., Goldenzweig, P., Gu, T., Gudkova, K., Hadjivasiliou, C., Hara, T., Hayasaka, K., Hazra, S., Hedges, M. T., Herrmann, D., Hou, W. -S., Hsu, C. -L., Inami, K., Ipsita, N., Ishikawa, A., Itoh, R., Iwasaki, M., Iwasaki, Y., Jacobs, W. W., Jang, E. -J., Jia, S., Jin, Y., Joo, K. K., Kaliyar, A. B., Kawasaki, T., Kiesling, C., Kim, C. H., Kim, D. Y., Kim, K. -H., Kim, Y. -K., Kinoshita, K., Kodyš, P., Korobov, A., Korpar, S., Kovalenko, E., Križan, P., Krokovny, P., Kumar, M., Kumar, R., Kuzmin, A., Kwon, Y. -J., Lai, Y. -T., Lam, T., Laurenza, M., Lee, S. C., Levit, D., Li, L. K., Libby, J., Lieret, K., Liventsev, D., Ma, Y., Masuda, M., Matsuda, T., Maurya, S. K., Meier, F., Merola, M., Metzner, F., Miyabayashi, K., Mohanty, G. B., Nakamura, I., Nakano, T., Nakao, M., Natkaniec, Z., Natochii, A., Nayak, L., Nisar, N. K., Nishida, S., Ogawa, K., Ogawa, S., Ono, H., Oskin, P., Pakhlov, P., Pakhlova, G., Pang, T., Pardi, S., Park, H., Park, J., Park, S. -H., Passeri, A., Patra, S., Paul, S., Pedlar, T. K., Pestotnik, R., Piilonen, L. E., Podobnik, T., Prencipe, E., Prim, M. T., Rout, N., Russo, G., Sahoo, D., Sakai, Y., Sandilya, S., Santelj, L., Savinov, V., Schnell, G., Schwanda, C., Schwartz, A. J., Seino, Y., Senyo, K., Shan, W., Shapkin, M., Sharma, C., Shiu, J. -G., Sokolov, A., Solovieva, E., Starič, M., Stottler, Z. S., Sumihama, M., Sutcliffe, W., Takizawa, M., Tanida, K., Tenchini, F., Tiwary, R., Trabelsi, K., Uchida, M., Unno, Y., Uno, S., Usov, Y., Vahsen, S. E., Varner, G., Vinokurova, A., Wang, D., Wang, E., Wang, M. -Z., Wang, X. L., Watanabe, M., Watanuki, S., Werbycka, O., Won, E., Yabsley, B. D., Yan, W., Yin, J. H., Yuan, C. Z., Yuan, L., Zhang, Z. P., and Zhilich, V.

Subjects
High Energy Physics - Experiment
Abstract

We report the first measurement of the inclusive $e^+e^- \to b\bar{b} \to D_s^{\pm}X$ and $e^+e^- \to b\bar{b} \to D^0/\bar{D}^0X$ cross sections in the energy range from $10.63$ to $11.02$. Based on these results, we determine $\sigma(e^+ e^- \to B_s^0 \bar{B}_s^0 X)$ and $\sigma(e^+ e^- \to B\bar{B}X)$ in the same energy range. We measure the fraction of $B_s^0$ events at $\Upsilon(10860)$ to be $f_{\rm s}=(22.0^{+2.0}_{-2.1})\%$. We determine also the ratio of the $B_s^0$ inclusive branching fractions $\mathcal{B}(B_s^0 \to D^0/\bar{D}^0X)/\mathcal{B}(B_s^0 \to D_s^{\pm} X)=0.416 \pm 0.018 \pm 0.092$. The results are obtained using the data collected with the Belle detector at the KEKB asymmetric-energy $e^+e^-$ collider.

Published
2023
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254. Measurement of $C\!P$ violation in $B^{0}\rightarrow K_{S}^{0}\pi^{0}$ decays at Belle II

Author

Belle II Collaboration, Adachi, I., Adamczyk, K., Aggarwal, L., Ahmed, H., Aihara, H., Akopov, N., Aloisio, A., Ky, N. Anh, Asner, D. M., Atmacan, H., Aushev, T., Aushev, V., Aversano, M., Babu, V., Bae, H., Bahinipati, S., Bambade, P., Banerjee, Sw., Barrett, M., Baudot, J., Bauer, M., Baur, A., Beaubien, A., Becker, J., Behera, P. K., Bennett, J. V., Bertacchi, V., Bertemes, M., Bertholet, E., Bessner, M., Bettarini, S., Bhuyan, B., Bianchi, F., Bilka, T., Biswas, D., Bodrov, D., Bondar, A., Borah, J., Bozek, A., Bračko, M., Branchini, P., Briere, R. A., Browder, T. E., Budano, A., Bussino, S., Campajola, M., Cao, L., Casarosa, G., Cecchi, C., Cerasoli, J., Chang, P., Cheaib, R., Cheema, P., Chekelian, V., Chen, C., Cheon, B. G., Chilikin, K., Chirapatpimol, K., Cho, H. -E., Cho, K., Cho, S. -J., Choi, S. -K., Choudhury, S., Cochran, J., Corona, L., Cremaldi, L. M., Das, S., Dattola, F., De La Cruz-Burelo, E., De La Motte, S. A., de Marino, G., De Nuccio, M., De Pietro, G., de Sangro, R., Destefanis, M., De Yta-Hernandez, A., Dhamija, R., Di Canto, A., Di Capua, F., Dingfelder, J., Doležal, Z., Jiménez, I. Domínguez, Dong, T. V., Dorigo, M., Dort, K., Dreyer, S., Dubey, S., Dujany, G., Ecker, P., Eliachevitch, M., Feichtinger, P., Ferber, T., Ferlewicz, D., Fillinger, T., Finck, C., Finocchiaro, G., Fodor, A., Forti, F., Fulsom, B. G., Gabrielli, A., Ganiev, E., Garcia-Hernandez, M., Garg, R., Garmash, A., Gaudino, G., Gaur, V., Gaz, A., Gellrich, A., Ghosh, D., Giakoustidis, G., Giordano, R., Giri, A., Glazov, A., Gobbo, B., Godang, R., Goldenzweig, P., Gradl, W., Grammatico, T., Granderath, S., Graziani, E., Greenwald, D., Gruberová, Z., Gu, T., Guan, Y., Gudkova, K., Halder, S., Han, Y., Hara, K., Hara, T., Hayasaka, K., Hayashii, H., Hazra, S., Hearty, C., Hedges, M. T., de la Cruz, I. Heredia, Villanueva, M. Hernández, Hershenhorn, A., Higuchi, T., Hill, E. C., Hoek, M., Hohmann, M., Hsu, C. -L., Humair, T., Iijima, T., Inami, K., Ipsita, N., Ishikawa, A., Ito, S., Itoh, R., Iwasaki, M., Jackson, P., Jacobs, W. W., Jang, E. -J., Ji, Q. P., Jia, S., Jin, Y., Johnson, A., Joo, K. K., Junkerkalefeld, H., Kaleta, M., Kaliyar, A. B., Kandra, J., Kang, K. H., Kang, S., Kar, S., Karyan, G., Kawasaki, T., Keil, F., Ketter, C., Kiesling, C., Kim, C. -H., Kim, D. Y., Kim, K. -H., Kim, Y. -K., Kindo, H., Kodyš, P., Koga, T., Kohani, S., Kojima, K., Korobov, A., Korpar, S., Kovalenko, E., Kowalewski, R., Kraetzschmar, T. M. G., Križan, P., Krokovny, P., Kuhr, T., Kumar, J., Kumar, M., Kumara, K., Kunigo, T., Kuzmin, A., Kwon, Y. -J., Lacaprara, S., Lai, Y. -T., Lam, T., Lange, J. S., Laurenza, M., Leboucher, R., Diberder, F. R. Le, Leitl, P., Levit, D., Li, C., Li, L. K., Libby, J., Liu, Q. Y., Liu, Z. Q., Liventsev, D., Longo, S., Lueck, T., Luo, T., Lyu, C., Ma, Y., Maggiora, M., Maharana, S. P., Maiti, R., Maity, S., Mancinelli, G., Manfredi, R., Manoni, E., Mantovano, M., Marcantonio, D., Marcello, S., Marinas, C., Martel, L., Martellini, C., Martinov, T., Massaccesi, L., Masuda, M., Matsuda, T., Matsuoka, K., Matvienko, D., Maurya, S. K., McKenna, J. A., Mehta, R., Meier, F., Merola, M., Metzner, F., Milesi, M., Miller, C., Mirra, M., Miyabayashi, K., Mizuk, R., Mohanty, G. B., Molina-Gonzalez, N., Mondal, S., Moneta, S., Moser, H. -G., Mrvar, M., Mussa, R., Nakamura, I., Nakazawa, Y., Charan, A. Narimani, Naruki, M., Natochii, A., Nayak, L., Nayak, M., Nazaryan, G., Nisar, N. K., Nishida, S., Ono, H., Onuki, Y., Oskin, P., Pakhlov, P., Pakhlova, G., Paladino, A., Paoloni, E., Pardi, S., Parham, K., Park, H., Park, S. -H., Passeri, A., Patra, S., Paul, S., Pedlar, T. K., Peschke, R., Pestotnik, R., Pham, F., Piccolo, M., Piilonen, L. E., Podesta-Lerma, P. L. M., Podobnik, T., Pokharel, S., Praz, C., Prell, S., Prencipe, E., Prim, M. T., Purwar, H., Rad, N., Rados, P., Raeuber, G., Raiz, S., Reif, M., Reiter, S., Remnev, M., Ripp-Baudot, I., Rizzo, G., Robertson, S. H., Roehrken, M., Roney, J. M., Rostomyan, A., Rout, N., Russo, G., Sahoo, D., Sandilya, S., Sangal, A., Santelj, L., Sato, Y., Savinov, V., Scavino, B., Schmitt, C., Schwanda, C., Schwartz, A. J., Seino, Y., Selce, A., Senyo, K., Serrano, J., Sevior, M. E., Sfienti, C., Shan, W., Sharma, C., Shi, X. D., Shillington, T., Shiu, J. -G., Shtol, D., Sibidanov, A., Simon, F., Singh, J. B., Skorupa, J., Sobie, R. J., Sobotzik, M., Soffer, A., Sokolov, A., Solovieva, E., Spataro, S., Spruck, B., Starič, M., Stavroulakis, P., Stefkova, S., Stottler, Z. S., Stroili, R., Sumihama, M., Sumisawa, K., Sutcliffe, W., Svidras, H., Takahashi, M., Takizawa, M., Tamponi, U., Tanaka, S., Tanida, K., Tenchini, F., Thaller, A., Tittel, O., Tiwary, R., Tonelli, D., Torassa, E., Trabelsi, K., Tsaklidis, I., Uchida, M., Ueda, I., Uglov, T., Unger, K., Unno, Y., Uno, K., Uno, S., Urquijo, P., Ushiroda, Y., Vahsen, S. E., van Tonder, R., Varner, G. S., Varvell, K. E., Vinokurova, A., Vismaya, V. S., Vitale, L., Wach, B., Wakai, M., Wakeling, H. M., Wallner, S., Wang, E., Wang, M. -Z., Wang, Z., Warburton, A., Watanabe, M., Watanuki, S., Welsch, M., Wessel, C., Won, E., Xu, X. P., Yabsley, B. D., Yamada, S., Yan, W., Yang, S. B., Yin, J. H., Yoshihara, K., Yuan, C. Z., Yusa, Y., Zani, L., Zhang, Y., Zhilich, V., Zhou, Q. D., and Zhukova, V. I.

Subjects
High Energy Physics - Experiment
Abstract

We report a measurement of the $C\!P$-violating parameters $A$ and $S$ in $B^{0}\to K_{S}^{0} \pi^{0}$ decays at Belle II using a sample of $387\times 10^{6}$ $B\bar{B}$ events recorded in $e^{+}e^{-}$ collisions at a center-of-mass energy corresponding to the $\Upsilon(4S)$ resonance. These parameters are determined by fitting the proper decay-time distribution of a sample of 415 signal events. We obtain $A = 0.04^{+0.15}_{-0.14}\pm 0.05$ and $S = 0.75^{+0.20}_{-0.23}\pm 0.04$, where the first uncertainties are statistical and the second are systematic.

Published
2023
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255. Surgical tool classification and localization: results and methods from the MICCAI 2022 SurgToolLoc challenge

Author

Zia, Aneeq, Bhattacharyya, Kiran, Liu, Xi, Berniker, Max, Wang, Ziheng, Nespolo, Rogerio, Kondo, Satoshi, Kasai, Satoshi, Hirasawa, Kousuke, Liu, Bo, Austin, David, Wang, Yiheng, Futrega, Michal, Puget, Jean-Francois, Li, Zhenqiang, Sato, Yoichi, Fujii, Ryo, Hachiuma, Ryo, Masuda, Mana, Saito, Hideo, Wang, An, Xu, Mengya, Islam, Mobarakol, Bai, Long, Pang, Winnie, Ren, Hongliang, Nwoye, Chinedu, Sestini, Luca, Padoy, Nicolas, Nielsen, Maximilian, Schüttler, Samuel, Sentker, Thilo, Husseini, Hümeyra, Baltruschat, Ivo, Schmitz, Rüdiger, Werner, René, Matsun, Aleksandr, Farooq, Mugariya, Saaed, Numan, Viera, Jose Renato Restom, Yaqub, Mohammad, Getty, Neil, Xia, Fangfang, Zhao, Zixuan, Duan, Xiaotian, Yao, Xing, Lou, Ange, Yang, Hao, Han, Jintong, Noble, Jack, Wu, Jie Ying, Alshirbaji, Tamer Abdulbaki, Jalal, Nour Aldeen, Arabian, Herag, Ding, Ning, Moeller, Knut, Chen, Weiliang, He, Quan, Bilal, Muhammad, Akinosho, Taofeek, Qayyum, Adnan, Caputo, Massimo, Vohra, Hunaid, Loizou, Michael, Ajayi, Anuoluwapo, Berrou, Ilhem, Niyi-Odumosu, Faatihah, Maier-Hein, Lena, Stoyanov, Danail, Speidel, Stefanie, and Jarc, Anthony

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

The ability to automatically detect and track surgical instruments in endoscopic videos can enable transformational interventions. Assessing surgical performance and efficiency, identifying skilled tool use and choreography, and planning operational and logistical aspects of OR resources are just a few of the applications that could benefit. Unfortunately, obtaining the annotations needed to train machine learning models to identify and localize surgical tools is a difficult task. Annotating bounding boxes frame-by-frame is tedious and time-consuming, yet large amounts of data with a wide variety of surgical tools and surgeries must be captured for robust training. Moreover, ongoing annotator training is needed to stay up to date with surgical instrument innovation. In robotic-assisted surgery, however, potentially informative data like timestamps of instrument installation and removal can be programmatically harvested. The ability to rely on tool installation data alone would significantly reduce the workload to train robust tool-tracking models. With this motivation in mind we invited the surgical data science community to participate in the challenge, SurgToolLoc 2022. The goal was to leverage tool presence data as weak labels for machine learning models trained to detect tools and localize them in video frames with bounding boxes. We present the results of this challenge along with many of the team's efforts. We conclude by discussing these results in the broader context of machine learning and surgical data science. The training data used for this challenge consisting of 24,695 video clips with tool presence labels is also being released publicly and can be accessed at https://console.cloud.google.com/storage/browser/isi-surgtoolloc-2022.

Published
2023

256. Search for lepton-flavor-violating $\tau^- \to \ell^-\phi$ decays in 2019-2021 Belle II data

Author

Belle II Collaboration, Abudinén, F., Adachi, I., Adamczyk, K., Aggarwal, L., Ahlburg, P., Ahmed, H., Ahn, J. K., Aihara, H., Akopov, N., Aloisio, A., Andricek, L., Ky, N. Anh, Asner, D. M., Atmacan, H., Aulchenko, V., Aushev, T., Aushev, V., Aversano, M., Babu, V., Bacher, S., Bae, H., Bahinipati, S., Bakich, A. M., Bambade, P., Banerjee, Sw., Bansal, S., Barrett, M., Batignani, G., Baudot, J., Bauer, M., Baur, A., Beaulieu, A., Becker, J., Behera, P. K., Bennett, J. V., Bernieri, E., Bernlochner, F. U., Bertacchi, V., Bertemes, M., Bertholet, E., Bessner, M., Bettarini, S., Bhardwaj, V., Bhuyan, B., Bianchi, F., Bilka, T., Bilokin, S., Biswas, D., Bobrov, A., Bodrov, D., Bolz, A., Bondar, A., Bonvicini, G., Borah, J., Bozek, A., Bračko, M., Branchini, P., Briere, R. A., Browder, T. E., Brown, D. N., Budano, A., Bussino, S., Campajola, M., Cao, L., Casarosa, G., Cecchi, C., Cerasoli, J., Červenkov, D., Chang, M. -C., Chang, P., Cheaib, R., Cheema, P., Chekelian, V., Chen, C., Chen, Y. Q., Chen, Y. -T., Cheon, B. G., Chilikin, K., Chirapatpimol, K., Cho, H. -E., Cho, K., Cho, S. -J., Choi, S. -K., Choudhury, S., Cinabro, D., Cochran, J., Corona, L., Cremaldi, L. M., Cunliffe, S., Czank, T., Das, S., Dattola, F., De La Cruz-Burelo, E., De La Motte, S. A., de Marino, G., De Nardo, G., De Nuccio, M., De Pietro, G., de Sangro, R., Deschamps, B., Destefanis, M., Dey, S., De Yta-Hernandez, A., Dhamija, R., Di Canto, A., Di Capua, F., Dingfelder, J., Doležal, Z., Jiménez, I. Domínguez, Dong, T. V., Dorigo, M., Dort, K., Dossett, D., Dreyer, S., Dubey, S., Duell, S., Dujany, G., Ecker, P., Eliachevitch, M., Epifanov, D., Feichtinger, P., Ferber, T., Ferlewicz, D., Fillinger, T., Finck, C., Finocchiaro, G., Fischer, P., Flood, K., Fodor, A., Forti, F., Frey, A., Friedl, M., Fulsom, B. G., Gabrielli, A., Gabyshev, N., Ganiev, E., Garcia-Hernandez, M., Garg, R., Garmash, A., Gaudino, G., Gaur, V., Gaz, A., Gebauer, U., Gellrich, A., Ghevondyan, G., Ghosh, D., Giakoustidis, G., Giordano, R., Giri, A., Glazov, A., Gobbo, B., Godang, R., Goldenzweig, P., Golob, B., Gong, G., Grace, P., Gradl, W., Graf-Schreiber, M., Grammatico, T., Granderath, S., Graziani, E., Greenwald, D., Gruberová, Z., Gu, T., Guan, Y., Gudkova, K., Hadjivasiliou, C., Halder, S., Han, Y., Hara, K., Hara, T., Hartbrich, O., Hayasaka, K., Hayashii, H., Hazra, S., Hearty, C., Hedges, M. T., de la Cruz, I. Heredia, Villanueva, M. Hernández, Hershenhorn, A., Higuchi, T., Hill, E. C., Hirata, H., Hoek, M., Hohmann, M., Hotta, T., Hsu, C. -L., Huang, K., Humair, T., Iijima, T., Inami, K., Inguglia, G., Ipsita, N., Jabbar, J. Irakkathil, Ishikawa, A., Ito, S., Itoh, R., Iwasaki, M., Iwasaki, Y., Iwata, S., Jackson, P., Jacobs, W. W., Jaffe, D. E., Jang, E. -J., Jeon, H. B., Ji, Q. P., Jia, S., Jin, Y., Joo, K. K., Junkerkalefeld, H., Kadenko, I., Kakuno, H., Kaleta, M., Kalita, D., Kaliyar, A. B., Kandra, J., Kang, K. H., Kang, S., Kapusta, P., Karl, R., Karyan, G., Kato, Y., Kawasaki, T., Ketter, C., Kiesling, C., Kim, C. -H., Kim, D. Y., Kim, H. J., Kim, K. -H., Kim, Y. -K., Kim, Y. J., Kimmel, T. D., Kindo, H., Kinoshita, K., Kleinwort, C., Kodyš, P., Koga, T., Kohani, S., Kojima, K., Konno, T., Korobov, A., Korpar, S., Kovalenko, E., Kowalewski, R., Kraetzschmar, T. M. G., Križan, P., Krohn, J. F., Krokovny, P., Kuehn, W., Kuhr, T., Kumar, J., Kumar, M., Kumar, R., Kumara, K., Kumita, T., Kunigo, T., Kurz, S., Kuzmin, A., Kvasnička, P., Kwon, Y. -J., Lacaprara, S., Lai, Y. -T., La Licata, C., Lalwani, K., Lam, T., Lanceri, L., Lange, J. S., Laurenza, M., Lautenbach, K., Laycock, P. J., Leboucher, R., Diberder, F. R. Le, Lee, S. C., Leitl, P., Levit, D., Lewis, P. M., Li, C., Li, L. K., Li, S. X., Li, Y. B., Libby, J., Lieret, K., Lin, J., Liptak, Z., Liu, Q. Y., Liu, Z. A., Liu, Z. Q., Liventsev, D., Longo, S., Lozar, A., Lueck, T., Luo, T., Lyu, C., Ma, Y., Maggiora, M., Maharana, S. P., Maiti, R., Maity, S., Manfredi, R., Manoni, E., Manthei, A. C., Mantovano, M., Marcantonio, D., Marcello, S., Marinas, C., Martel, L., Martellini, C., Martini, A., Martinov, T., Massaccesi, L., Masuda, M., Matsuda, T., Matsuoka, K., Matvienko, D., Maurya, S. K., McKenna, J. A., McNeil, J., Meggendorfer, F., Meier, F., Merola, M., Metzner, F., Milesi, M., Miller, C., Miyabayashi, K., Miyake, H., Miyata, H., Mizuk, R., Mohanty, G. B., Molina-Gonzalez, N., Mondal, S., Moneta, S., Moon, H., Moser, H. -G., Mrvar, M., Muller, Th., Mussa, R., Nakamura, I., Nakamura, K. R., Nakano, E., Nakao, M., Nakayama, H., Nakazawa, H., Nakazawa, Y., Charan, A. Narimani, Naruki, M., Narwal, D., Natkaniec, Z., Natochii, A., Nayak, L., Nayak, M., Nazaryan, G., Niebuhr, C., Niiyama, M., Ninkovic, J., Nisar, N. K., Nishida, S., Nishimura, K., Nouxman, M. H. A., Ogawa, K., Ogawa, S., Olsen, S. L., Onishchuk, Y., Ono, H., Onuki, Y., Oskin, P., Oxford, E. R., Ozaki, H., Pakhlov, P., Pakhlova, G., Paladino, A., Pang, T., Panta, A., Paoloni, E., Pardi, S., Parham, K., Park, H., Park, S. -H., Paschen, B., Passeri, A., Pathak, A., Patra, S., Paul, S., Pedlar, T. K., Peruzzi, I., Peschke, R., Pestotnik, R., Pham, F., Piccolo, M., Piilonen, L. E., Angioni, G. Pinna, Podesta-Lerma, P. L. M., Podobnik, T., Pokharel, S., Polat, L., Popov, V., Praz, C., Prell, S., Prencipe, E., Prim, M. T., Purohit, M. V., Purwar, H., Rad, N., Rados, P., Raeuber, G., Raiz, S., Morales, A. Ramirez, Rauls, N., Reif, M., Reiter, S., Remnev, M., Ripp-Baudot, I., Ritter, M., Ritzert, M., Rizzo, G., Rizzuto, L. B., Robertson, S. H., Rocchetti, P., Pérez, D. Rodríguez, Roehrken, M., Roney, J. M., Rosenfeld, C., Rostomyan, A., Rout, N., Rozanska, M., Russo, G., Sahoo, D., Sakai, Y., Sanders, D. A., Sandilya, S., Sangal, A., Santelj, L., Sartori, P., Sato, Y., Savinov, V., Scavino, B., Schmitt, C., Schmitz, J., Schnepf, M., Schreeck, H., Schueler, J., Schwanda, C., Schwartz, A. J., Schwenker, B., Schwickardi, M., Seino, Y., Selce, A., Senyo, K., Serrano, J., Sevior, M. E., Sfienti, C., Shan, W., Sharma, C., Shebalin, V., Shen, C. P., Shi, X. D., Shibuya, H., Shillington, T., Shiu, J. -G., Shtol, D., Shwartz, B., Sibidanov, A., Simon, F., Singh, J. B., Skorupa, J., Smith, K., Sobie, R. J., Soffer, A., Sokolov, A., Soloviev, Y., Solovieva, E., Spataro, S., Spruck, B., Starič, M., Stavroulakis, P., Stefkova, S., Stottler, Z. S., Stroili, R., Strube, J., Stypula, J., Sue, Y., Sugiura, R., Sumihama, M., Sumisawa, K., Sutcliffe, W., Suzuki, S. Y., Svidras, H., Tabata, M., Takahashi, M., Takizawa, M., Tamponi, U., Tanaka, S., Tanida, K., Tanigawa, H., Taniguchi, N., Tao, Y., Tenchini, F., Thaller, A., Tittel, O., Tiwary, R., Tonelli, D., Torassa, E., Toutounji, N., Trabelsi, K., Tsaklidis, I., Tsuboyama, T., Tsuzuki, N., Uchida, M., Ueda, I., Uehara, S., Uematsu, Y., Ueno, T., Uglov, T., Unger, K., Unno, Y., Uno, K., Uno, S., Urquijo, P., Ushiroda, Y., Usov, Y. V., Vahsen, S. E., van Tonder, R., Varner, G. S., Varvell, K. E., Vinokurova, A., Vismaya, V. S., Vitale, L., Vobbilisetti, V., Vorobyev, V., Vossen, A., Wach, B., Waheed, E., Wakai, M., Wakeling, H. M., Wallner, S., Abdullah, W. Wan, Wang, B., Wang, C. H., Wang, E., Wang, M. -Z., Wang, X. L., Wang, Z., Warburton, A., Watanabe, M., Watanuki, S., Webb, J., Wehle, S., Welsch, M., Werbycka, O., Wessel, C., Wiechczynski, J., Wieduwilt, P., Windel, H., Won, E., Wu, L. J., Xie, Y., Xu, X. P., Yabsley, B. D., Yamada, S., Yan, W., Yang, S. B., Yelton, J., Yin, J. H., Yook, Y. M., Yoshihara, K., Yuan, C. Z., Yusa, Y., Zani, L., Zhang, J. Z., Zhang, Y., Zhang, Z., Zhilich, V., Zhou, J. S., Zhou, Q. D., Zhou, X. Y., Zhukova, V. I., Zhulanov, V., and Žlebčík, R.

Subjects
High Energy Physics - Experiment
Abstract

We report a search for lepton-flavor-violating decays $\tau^- \to \ell^- \phi$ ($\ell^- =e^-,\mu^-$) at the Belle II experiment, using a sample of electron-positron data produced at the SuperKEKB collider in 2019-2021 and corresponding to an integrated luminosity of 190 fb$^{-1}$. We use a new untagged selection for $e^+e^- \to \tau^+\tau^-$ events, where the signal $\tau$ is searched for as a neutrinoless final state of a single charged lepton and a $\phi$ meson and the other $\tau$ is not reconstructed in any specific decay mode, in contrast to previous measurements by the BaBar and Belle experiments. We find no evidence for $\tau^- \to \ell^- \phi$ decays and obtain upper limits on the branching fractions at 90% confidence level of 23 $\times 10^{-8}$ and 9.7$\times 10^{-8}$ for $\tau^- \rightarrow e^-\phi$ and $\tau^- \rightarrow \mu^-\phi$, respectively

Published
2023

257. To Trust or Not to Trust: Evolutionary Dynamics of an Asymmetric N-player Trust Game

Author

Lim, Ik Soo and Masuda, Naoki

Subjects
Physics - Physics and Society
Abstract

Trusting others and reciprocating the received trust with trustworthy actions are fundaments of economic and social interactions. The trust game (TG) is widely used for studying trust and trustworthiness and entails a sequential interaction between two players, an investor and a trustee. It requires at least two strategies or options for an investor (e.g. to trust versus not to trust a trustee). According to the evolutionary game theory, the antisocial strategies (e.g. not to trust) evolve such that the investor and trustee end up with lower payoffs than those that they would get with the prosocial strategies (e.g.to trust). A generalisation of the TG to a multiplayer (i.e.more than two players) TG was recently proposed. However, its outcomes hinge upon two assumptions that various real situations may substantially deviate from: (i) investors are forced to trust trustees and (ii) investors can turn into trustees by imitation and vice versa. We propose an asymmetric multiplayer TG that allows investors not to trust and prohibits the imitation between players of different roles; instead, investors learn from other investors and the same for trustees. We show that the evolutionary game dynamics of the proposed TG qualitatively depends on the nonlinearity of the payoff function and the amount of incentives collected from and distributed to players through an institution. We also show that incentives given to trustees can be useful and sufficient to cost-effectively promote trust and trustworthiness among self-interested players., Comment: 14 pages, 6 figures

Published
2023
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258. Observation of ${B\to D^{(*)} K^- K^{0}_S}$ decays using the 2019-2022 Belle II data sample

Author

Belle II Collaboration, Abudinén, F., Adachi, I., Adamczyk, K., Aggarwal, L., Ahlburg, P., Ahmed, H., Ahn, J. K., Aihara, H., Akopov, N., Aloisio, A., Andricek, L., Ky, N. Anh, Asner, D. M., Atmacan, H., Aulchenko, V., Aushev, T., Aushev, V., Aversano, M., Babu, V., Bacher, S., Bae, H., Bahinipati, S., Bakich, A. M., Bambade, P., Banerjee, Sw., Bansal, S., Barrett, M., Batignani, G., Baudot, J., Bauer, M., Baur, A., Beaulieu, A., Becker, J., Behera, P. K., Bennett, J. V., Bernieri, E., Bernlochner, F. U., Bertacchi, V., Bertemes, M., Bertholet, E., Bessner, M., Bettarini, S., Bhardwaj, V., Bhuyan, B., Bianchi, F., Bilka, T., Bilokin, S., Biswas, D., Bobrov, A., Bodrov, D., Bolz, A., Bondar, A., Bonvicini, G., Borah, J., Bozek, A., Bračko, M., Branchini, P., Briere, R. A., Browder, T. E., Brown, D. N., Budano, A., Bussino, S., Campajola, M., Cao, L., Casarosa, G., Cecchi, C., Cerasoli, J., Červenkov, D., Chang, M. -C., Chang, P., Cheaib, R., Cheema, P., Chekelian, V., Chen, C., Chen, Y. Q., Chen, Y. -T., Cheon, B. G., Chilikin, K., Chirapatpimol, K., Cho, H. -E., Cho, K., Cho, S. -J., Choi, S. -K., Choudhury, S., Cinabro, D., Cochran, J., Corona, L., Cremaldi, L. M., Cunliffe, S., Czank, T., Das, S., Dattola, F., De La Cruz-Burelo, E., De La Motte, S. A., de Marino, G., De Nardo, G., De Nuccio, M., De Pietro, G., de Sangro, R., Deschamps, B., Destefanis, M., Dey, S., De Yta-Hernandez, A., Dhamija, R., Di Canto, A., Di Capua, F., Dingfelder, J., Doležal, Z., Jiménez, I. Domínguez, Dong, T. V., Dorigo, M., Dort, K., Dossett, D., Dreyer, S., Dubey, S., Duell, S., Dujany, G., Ecker, P., Eliachevitch, M., Epifanov, D., Feichtinger, P., Ferber, T., Ferlewicz, D., Fillinger, T., Finck, C., Finocchiaro, G., Fischer, P., Flood, K., Fodor, A., Forti, F., Frey, A., Friedl, M., Fulsom, B. G., Gabrielli, A., Gabyshev, N., Ganiev, E., Garcia-Hernandez, M., Garg, R., Garmash, A., Gaudino, G., Gaur, V., Gaz, A., Gebauer, U., Gellrich, A., Ghevondyan, G., Ghosh, D., Giakoustidis, G., Giordano, R., Giri, A., Glazov, A., Gobbo, B., Godang, R., Goldenzweig, P., Golob, B., Gong, G., Grace, P., Gradl, W., Graf-Schreiber, M., Grammatico, T., Granderath, S., Graziani, E., Greenwald, D., Gruberová, Z., Gu, T., Guan, Y., Gudkova, K., Hadjivasiliou, C., Halder, S., Han, Y., Hara, K., Hara, T., Hartbrich, O., Hayasaka, K., Hayashii, H., Hazra, S., Hearty, C., Hedges, M. T., de la Cruz, I. Heredia, Villanueva, M. Hernández, Hershenhorn, A., Higuchi, T., Hill, E. C., Hirata, H., Hoek, M., Hohmann, M., Hotta, T., Hsu, C. -L., Huang, K., Humair, T., Iijima, T., Inami, K., Inguglia, G., Ipsita, N., Jabbar, J. Irakkathil, Ishikawa, A., Ito, S., Itoh, R., Iwasaki, M., Iwasaki, Y., Iwata, S., Jackson, P., Jacobs, W. W., Jaffe, D. E., Jang, E. -J., Jeon, H. B., Ji, Q. P., Jia, S., Jin, Y., Joo, K. K., Junkerkalefeld, H., Kadenko, I., Kakuno, H., Kaleta, M., Kalita, D., Kaliyar, A. B., Kandra, J., Kang, K. H., Kang, S., Kapusta, P., Karl, R., Karyan, G., Kato, Y., Kawasaki, T., Ketter, C., Kiesling, C., Kim, C. -H., Kim, D. Y., Kim, H. J., Kim, K. -H., Kim, Y. -K., Kim, Y. J., Kimmel, T. D., Kindo, H., Kinoshita, K., Kleinwort, C., Kodyš, P., Koga, T., Kohani, S., Kojima, K., Konno, T., Korobov, A., Korpar, S., Kovalenko, E., Kowalewski, R., Kraetzschmar, T. M. G., Križan, P., Krohn, J. F., Krokovny, P., Kuehn, W., Kuhr, T., Kumar, J., Kumar, M., Kumar, R., Kumara, K., Kumita, T., Kunigo, T., Kurz, S., Kuzmin, A., Kvasnička, P., Kwon, Y. -J., Lacaprara, S., Lai, Y. -T., La Licata, C., Lalwani, K., Lam, T., Lanceri, L., Lange, J. S., Laurenza, M., Lautenbach, K., Laycock, P. J., Leboucher, R., Diberder, F. R. Le, Lee, S. C., Leitl, P., Levit, D., Lewis, P. M., Li, C., Li, L. K., Li, S. X., Li, Y. B., Libby, J., Lieret, K., Lin, J., Liptak, Z., Liu, Q. Y., Liu, Z. A., Liu, Z. Q., Liventsev, D., Longo, S., Lozar, A., Lueck, T., Luo, T., Lyu, C., Ma, Y., Maggiora, M., Maharana, S. P., Maiti, R., Maity, S., Manfredi, R., Manoni, E., Manthei, A. C., Mantovano, M., Marcantonio, D., Marcello, S., Marinas, C., Martel, L., Martellini, C., Martini, A., Martinov, T., Massaccesi, L., Masuda, M., Matsuda, T., Matsuoka, K., Matvienko, D., Maurya, S. K., McKenna, J. A., McNeil, J., Meggendorfer, F., Meier, F., Merola, M., Metzner, F., Milesi, M., Miller, C., Miyabayashi, K., Miyake, H., Miyata, H., Mizuk, R., Mohanty, G. B., Molina-Gonzalez, N., Mondal, S., Moneta, S., Moon, H., Moser, H. -G., Mrvar, M., Muller, Th., Mussa, R., Nakamura, I., Nakamura, K. R., Nakano, E., Nakao, M., Nakayama, H., Nakazawa, H., Nakazawa, Y., Charan, A. Narimani, Naruki, M., Narwal, D., Natkaniec, Z., Natochii, A., Nayak, L., Nayak, M., Nazaryan, G., Niebuhr, C., Niiyama, M., Ninkovic, J., Nisar, N. K., Nishida, S., Nishimura, K., Nouxman, M. H. A., Ogawa, K., Ogawa, S., Olsen, S. L., Onishchuk, Y., Ono, H., Onuki, Y., Oskin, P., Oxford, E. R., Ozaki, H., Pakhlov, P., Pakhlova, G., Paladino, A., Pang, T., Panta, A., Paoloni, E., Pardi, S., Parham, K., Park, H., Park, S. -H., Paschen, B., Passeri, A., Pathak, A., Patra, S., Paul, S., Pedlar, T. K., Peruzzi, I., Peschke, R., Pestotnik, R., Pham, F., Piccolo, M., Piilonen, L. E., Angioni, G. Pinna, Podesta-Lerma, P. L. M., Podobnik, T., Pokharel, S., Polat, L., Popov, V., Praz, C., Prell, S., Prencipe, E., Prim, M. T., Purohit, M. V., Purwar, H., Rad, N., Rados, P., Raeuber, G., Raiz, S., Morales, A. Ramirez, Rauls, N., Reif, M., Reiter, S., Remnev, M., Ripp-Baudot, I., Ritter, M., Ritzert, M., Rizzo, G., Rizzuto, L. B., Robertson, S. H., Rocchetti, P., Pérez, D. Rodríguez, Roehrken, M., Roney, J. M., Rosenfeld, C., Rostomyan, A., Rout, N., Rozanska, M., Russo, G., Sahoo, D., Sakai, Y., Sanders, D. A., Sandilya, S., Sangal, A., Santelj, L., Sartori, P., Sato, Y., Savinov, V., Scavino, B., Schmitt, C., Schmitz, J., Schnepf, M., Schreeck, H., Schueler, J., Schwanda, C., Schwartz, A. J., Schwenker, B., Schwickardi, M., Seino, Y., Selce, A., Senyo, K., Serrano, J., Sevior, M. E., Sfienti, C., Shan, W., Sharma, C., Shebalin, V., Shen, C. P., Shi, X. D., Shibuya, H., Shillington, T., Shiu, J. -G., Shtol, D., Shwartz, B., Sibidanov, A., Simon, F., Singh, J. B., Skorupa, J., Smith, K., Sobie, R. J., Soffer, A., Sokolov, A., Soloviev, Y., Solovieva, E., Spataro, S., Spruck, B., Starič, M., Stavroulakis, P., Stefkova, S., Stottler, Z. S., Stroili, R., Strube, J., Stypula, J., Sue, Y., Sugiura, R., Sumihama, M., Sumisawa, K., Sutcliffe, W., Suzuki, S. Y., Svidras, H., Tabata, M., Takahashi, M., Takizawa, M., Tamponi, U., Tanaka, S., Tanida, K., Tanigawa, H., Taniguchi, N., Tao, Y., Tenchini, F., Thaller, A., Tittel, O., Tiwary, R., Tonelli, D., Torassa, E., Toutounji, N., Trabelsi, K., Tsaklidis, I., Tsuboyama, T., Tsuzuki, N., Uchida, M., Ueda, I., Uehara, S., Uematsu, Y., Ueno, T., Uglov, T., Unger, K., Unno, Y., Uno, K., Uno, S., Urquijo, P., Ushiroda, Y., Usov, Y. V., Vahsen, S. E., van Tonder, R., Varner, G. S., Varvell, K. E., Vinokurova, A., Vismaya, V. S., Vitale, L., Vobbilisetti, V., Vorobyev, V., Vossen, A., Wach, B., Waheed, E., Wakai, M., Wakeling, H. M., Wallner, S., Abdullah, W. Wan, Wang, B., Wang, C. H., Wang, E., Wang, M. -Z., Wang, X. L., Wang, Z., Warburton, A., Watanabe, M., Watanuki, S., Webb, J., Wehle, S., Welsch, M., Werbycka, O., Wessel, C., Wiechczynski, J., Wieduwilt, P., Windel, H., Won, E., Wu, L. J., Xie, Y., Xu, X. P., Yabsley, B. D., Yamada, S., Yan, W., Yang, S. B., Yelton, J., Yin, J. H., Yook, Y. M., Yoshihara, K., Yuan, C. Z., Yusa, Y., Zani, L., Zhang, J. Z., Zhang, Y., Zhang, Z., Zhilich, V., Zhou, J. S., Zhou, Q. D., Zhou, X. Y., Zhukova, V. I., Zhulanov, V., and Žlebčík, R.

Subjects
High Energy Physics - Experiment
Abstract

We present a measurement of the branching fractions of four $B^{0,-}\to D^{(*)+,0} K^- K^{0}_S$ decay modes. The measurement is based on data from SuperKEKB electron-positron collisions at the $\Upsilon(4S)$ resonance collected with the Belle II detector and corresponding to an integrated luminosity of ${362~\text{fb}^{-1}}$. The event yields are extracted from fits to the distributions of the difference between expected and observed $B$ meson energy to separate signal and background, and are efficiency-corrected as a function of the invariant mass of the $K^-K_S^0$ system. We find the branching fractions to be: \[ \text{B}(B^-\to D^0K^-K_S^0)=(1.89\pm 0.16\pm 0.10)\times 10^{-4}, \] \[ \text{B}(\overline B{}^0\to D^+K^-K_S^0)=(0.85\pm 0.11\pm 0.05)\times 10^{-4},\] \[ \text{B}(B^-\to D^{*0}K^-K_S^0)=(1.57\pm 0.27\pm 0.12)\times 10^{-4}, \] \[ \text{B}(\overline B{}^0\to D^{*+}K^-K_S^0)=(0.96\pm 0.18\pm 0.06)\times 10^{-4},\] where the first uncertainty is statistical and the second systematic. These results include the first observation of $\overline B{}^0\to D^+K^-K_S^0$, $B^-\to D^{*0}K^-K_S^0$, and $\overline B{}^0\to D^{*+}K^-K_S^0$ decays and a significant improvement in the precision of $\text{B}(B^-\to D^0K^-K_S^0)$ compared to previous measurements.

Published
2023

260. Factors Influencing Marker Expressions of Cultured Human Cord Blood-Derived Mast Cells.

Author

Alimohammadi, Shahrzad, Masuda-Kuroki, Kana, Szöllősi, Attila, and Di Nardo, Anna

Subjects
CD34+ cord blood-derived mast cells, FcεRI, MRGPRX2, TLR2, c-KIT, chymase, human stem cells, immune response, tryptase, Humans, Mast Cells, Fetal Blood, Toll-Like Receptor 2, Cells, Cultured, Cell Differentiation, RNA, Messenger, Nerve Tissue Proteins, Receptors, Neuropeptide, Receptors, G-Protein-Coupled
Abstract

Mast cells (MCs) are tissue-resident immune cells of a hematopoietic origin that play vital roles in innate and adaptive immunity. Human MCs can be isolated and differentiated from various tissue sources, including cord blood, when supplemented with cytokines such as stem cell factor, interleukin 3, and interleukin 6. Our current research study has shown significant differences in the marker expressions of human cord blood-derived mast cells (hCBMCs) based on donor dependency and the type of medium used for culturing and differentiation. These findings are particularly relevant given the challenges of obtaining specialty media influencing MC phenotypic marker expressions. We found that hCBMCs cultured in StemSpanTM-XF medium had a moderate expression of mast/stem cell growth factor receptor Kit (c-KIT) (mRNA and protein), low expressions of FcεRI (mRNA) and TLR2 (mRNA and protein) but had high levels of MRGPRX2 (mRNA and protein) expressions. In contrast, hCBMCs cultured in Stem Line II medium expressed FcεRI and TLR2 (mRNA and protein) with higher c-KIT but had lower MRGPRX2 expressions compared to the hCBMCs cultured in the StemSpanTM-XF medium. These results suggest that it is crucial to consider both donor dependency and the medium when investigating MC functions and that further research is needed to fully understand the impact of these factors on the hCBMC marker expressions.

Published
2023

261. The Role of Sphingolipids and Sphingosine-1-phosphate-Sphingosine-1-phosphate-receptor Signaling in Psoriasis.

Author

Masuda-Kuroki, Kana, Alimohammadi, Shahrzad, and Di Nardo, Anna

Subjects
ceramide, psoriasis, sphingolipid, sphingosine-1-phosphate, sphingosine-1-phosphate receptor
Abstract

Psoriasis is a long-lasting skin condition characterized by redness and thick silver scales on the skins surface. It involves various skin cells, including keratinocytes, dendritic cells, T lymphocytes, and neutrophils. The treatments for psoriasis range from topical to systemic therapies, but they only alleviate the symptoms and do not provide a fundamental cure. Moreover, systemic treatments have the disadvantage of suppressing the entire bodys immune system. Therefore, a new treatment strategy with minimal impact on the immune system is required. Recent studies have shown that sphingolipid metabolites, particularly ceramide and sphingosine-1-phosphate (S1P), play a significant role in psoriasis. Specific S1P-S1P-receptor (S1PR) signaling pathways have been identified as crucial to psoriasis inflammation. Based on these findings, S1PR modulators have been investigated and have been found to improve psoriasis inflammation. This review will discuss the metabolic pathways of sphingolipids, the individual functions of these metabolites, and their potential as a new therapeutic approach to psoriasis.

Published
2023

262. S. epidermidis Rescues Allergic Contact Dermatitis in Sphingosine 1-Phosphate Receptor 2-Deficient Skin.

Author

Masuda-Kuroki, Kana, Alimohammadi, Shahrzad, and Di Nardo, Anna

Subjects
3, 4-Dibutoxy-3-cyclobutene-1, 2-dione (SADBE), Staphylococcus epidermidis, contact dermatitis, sphingosine 1-phosphate, sphingosine 1-phosphate receptor 2, Animals, Mice, Sphingosine-1-Phosphate Receptors, Skin, Dermatitis, Allergic Contact, Claudin-1, Health Status, Staphylococcus epidermidis
Abstract

Recent studies have identified a subtype of the S1P-receptor family called sphingosine-1-phosphate receptor 2 (S1PR2), which plays a crucial role in maintaining the skin barrier. It has been observed that S1PR2 and Staphylococcus epidermidis (S. epidermidis) work together to regulate the skin barrier. However, the interaction between these two factors is still unclear. To investigate this, a study was conducted on healthy skin and allergic contact dermatitis (ACD) using 3,4-Dibutoxy-3-cyclobutene-1,2-dione (SADBE) on the ears of S1pr2fl/fl and S1pr2fl/flK14-Cre mice and using 1 × 106 CFU of S. epidermidis to examine its effects on the skin. The results showed that in S. epidermidis-conditioned ACD, the ear thickness of S1pr2fl/flK14-Cre mice was lower than that of S1pr2fl/fl mice, and mRNA expressions of Il-1β and Cxcl2 of S1pr2fl/flK14-Cre mice were lower than that of S1pr2fl/fl mice in ACD with S. epidermidis. Furthermore, the gene expression of Claudin-1 and Occludin in S1pr2fl/flK14-Cre mice was higher than that of S1pr2fl/fl mice in ACD with S. epidermidis. The study concludes that S. epidermidis colonization improves the skin barrier and prevents ACD even when S1P signaling malfunctions.

Published
2023

263. Cytokine Inhibitors Upregulate Extracellular Matrix Anabolism of Human Intervertebral Discs under Alginate Beads and Alginate-Embedded Explant Cultures.

Author

Kakutani, Kenichiro, Yurube, Takashi, An, Howard, Doita, Minoru, and Masuda, Koichi

Subjects
autocrine, cytokine, intervertebral disc metabolism, Humans, Cytokines, Intervertebral Disc Degeneration, Interleukin 1 Receptor Antagonist Protein, Intervertebral Disc, Extracellular Matrix, Proteoglycans, Receptors, Interleukin-1, Collagen
Abstract

We investigated the effects of the cytokine inhibitors IL-1 receptor antagonist (IL-1Ra) and soluble tumor necrosis factor receptor-1 (sTNFR1) on the extracellular matrix metabolism of human intervertebral discs (IVDs) and the roles of IL-1β and TNF in the homeostasis of IVD cells. The 1.2% alginate beads and the explants obtained from 35 human lumbar discs were treated with cytokine inhibitors. Extracellular matrix metabolism was evaluated by proteoglycan (PG) and collagen syntheses and IL-1β, TNF, and IL-6 expressions after three days of culture in the presence or absence of IL-1Ra, sTNFR1, and cycloheximide. Simultaneous treatment with IL-1Ra and sTNFR1 stimulated PG and collagen syntheses in the NP and AF cells and explants. The IL-1β concentration was significantly correlated to the relative increase in PG synthesis in AF explants after simultaneous cytokine inhibitor treatment. The relative increase in PG synthesis induced by simultaneous cytokine treatment was significantly higher in an advanced grade of MRI. Expressions of IL-1β and TNF were upregulated by each cytokine inhibitor, and simultaneous treatment suppressed IL-1β and TNF productions. In conclusion, IL-1Ra and sTNFR1 have the potential to increase PG and collagen synthesis in IVDs. IL-1β and TNF have a feedback pathway to maintain optimal expression, resulting in the control of homeostasis in IVD explants.

Published
2023

264. Large cervical endometrioid adenocarcinoma mimicking endometrial endometrioid adenocarcinoma: A case report

Author

Tomoko Oishi, MD, Kentaro Kai, MD, PhD, Motoko Tanabe, MD, Haruto Nishida, MD, PhD, Takashi Masuda, MD, PhD, Mitsutake Yano, MD, PhD, Yusuke Inomata, MD, and Eiji Kobayashi, MD, PhD

Subjects
Cervical adenocarcinoma, Endometrioid adenocarcinoma, Tumor location, Human papillomavirus, Chemoradiotherapy, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

ABSTRACT: Endometrioid adenocarcinoma of the uterine cervix is rare and difficult to distinguish from endometrial adenocarcinoma, particularly in large bulky cases. Herein, we report a rare case of a large endometrioid adenocarcinoma in a 58-year-old Japanese woman in which the tumor origin was difficult to identify. The patient presented with abdominal pain and vaginal bleeding and was referred to a gynecologist for suspected uterine cancer based on an evaluation performed at another institution. Imaging studies revealed an 11-cm cervical tumor without parametrial invasion, lymph node, distant metastases, or hydronephrosis, whereas cervical biopsy revealed an endometrioid adenocarcinoma. The patient was subsequently referred to our department for the determination of the tissue origin. The results of immunohistochemical staining were equivocal for cervical and endometrial origin. However, rectal examination confirmed a barrel-shaped cervix extending from the lower uterine segment to the hymenal ring. Human papillomavirus and microsatellite instability tests were negative. Finally, the patient was diagnosed with stage III endometrioid adenocarcinoma of the uterine cervix and achieved complete remission after concurrent chemoradiotherapy, followed by platinum-based systemic chemotherapy.

Published
2024
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265. Hepatic arterial infusion of autologous CD34+ cells for hepatitis C virus-related decompensated cirrhosis: A multicenter, open-label, exploratory randomized controlled trial

Author

Toru Nakamura, Atsutaka Masuda, Makoto Kako, Hirayuki Enomoto, Masaki Kaibori, Yasuyuki Fujita, Kyoko Tanizawa, Tetsuya Ioji, Yoshihiro Fujimori, Kei Fukami, Takuma Hazama, Hideki Iwamoto, Yasukazu Kako, Kaoru Kobayashi, Hironori Koga, Koji Nagafuji, Takayasu Ohtake, Hiroyuki Suzuki, Tomoyuki Takashima, Toshitaka Tsukiyama, Haruki Uojima, Kenichi Yamahara, Koichiro Yamakado, Hidekazu Yamamoto, Kazunori Yoh, Satoshi Yoshihara, Atsuhiko Kawamoto, Shuhei Nishiguchi, Shuzo Kobayashi, Takuji Torimura, and Takumi Kawaguchi

Subjects
CD34 antigens, Cell therapy, Clinical trial, Cirrhosis, Medicine (General), R5-920, Cytology, QH573-671
Abstract

Introduction: In this multicenter clinical study, we aimed to investigate the efficacy and safety of the transhepatic arterial administration of granulocyte-colony stimulating factor (G–CSF)–mobilized autologous peripheral blood (PB)-CD34+ cells compared with standard therapy in patients with decompensated cirrhosis type C. Methods: Patients were randomly assigned (2:1) to the CD34+ cell transplant (CD34+ cell) or standard-of-care (SOC) group and followed up for 52 weeks. The primary endpoints were the non-progression rate of Child-Pugh (CP) scores at 24 weeks post-enrollment and the safety of the protocol treatment. Results: Fourteen patients (CD34+ cell group: 10; SOC group: 4) were enrolled. CP scores at 24 weeks had a non-progression rate of 90% in the CD34+ cell group and 100% in the SOC group, with no significant difference between groups. Importantly, 4 out of 10 patients in the CD34+ cell group exhibited an improvement from decompensated to compensated cirrhosis, whereas all patients in the SOC group remained in decompensated cirrhosis. With regard to secondary endpoints, a trend toward increased serum albumin levels in the CD34+ cell group was noted. Serious adverse events (SAEs) occurred in three patients in the CD34+ cell group and in one patient in the SOC group. No causal relationship was observed between all SAEs and G-CSF, leukapheresis, or cell transplantation in the CD34+ cell group. No patients died and no hepatocellular carcinoma occurred within the study period. Conclusions: PB-CD34+ cell infusion therapy may have the potential to circumvent the decompensated stage of cirrhosis, thus avoiding the need for liver transplantation.

Published
2024
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266. Effectiveness of primary series, first, and second booster vaccination of monovalent mRNA COVID-19 vaccines against symptomatic SARS-CoV-2 infections and severe diseases during the SARS-CoV-2 omicron BA.5 epidemic in Japan: vaccine effectiveness real-time surveillance for SARS-CoV-2 (VERSUS)

Author

Haruka Maeda, Nobuo Saito, Ataru Igarashi, Masayuki Ishida, Mayumi Terada, Shingo Masuda, Ryosuke Osawa, Naoto Hosokawa, Kei Nakashima, Hiroshi Kamura, Haruki Imura, Hiroki Inoue, Suguru Matsuzaka, Yukihiro Sugimoto, Osamu Kuwamitsu, Iori Motohashi, Toru Morikawa, Rentaro Oda, Yuiko Hoshina, Takashi Matono, Osamu Teshigahara, Eiichiro Sando, Sadaharu Asami, Satoshi Kudo, Noboru Akizuki, Yoshikazu Muto, Tomoichiro Hayakawa, Tomoo Kishaba, Yasuji Ohara, Yoshinao Kubo, Motoi Suzuki, and Konosuke Morimoto

Subjects
BA.5, COVID-19, Japan, SARS-CoV-2, vaccine effectiveness, monovalent, Internal medicine, RC31-1245
Abstract

ABSTRACTBackground This study aimed to evaluate VE of primary, first, and second booster ancestral-strain monovalent mRNA COVID-19 vaccination against symptomatic infections and severe diseases in Japan.Methods We conducted a test-negative case-control study. We included medically attended episodes and hospitalizations involving individuals aged [Formula: see text]16 with signs and symptoms from July to November 2022, when Omicron BA.5 was dominant nationwide. To evaluate VE, we calculated adjusted ORs of vaccination among test-positive versus test-negative individuals using a mixed-effects logistic regression.Results For VE against symptomatic infections among individuals aged 16 to 59, VE of primary vaccination at > 180 days was 26.1% (95% CI: 10.6–38.8%); VE of the first booster was 58.5% (48.4–66.7%) at [Formula: see text]90 days, decreasing to 41.1% (29.5–50.8%) at 91 to 180 days. For individuals aged [Formula: see text]60, VE of the first booster was 42.8% (1.7–66.7%) at [Formula: see text]90 days, dropping to 15.4% (−25.9–43.2%) at 91 to 180 days, and then increasing to 44.0% (16.4–62.5%) after the second booster. For VE against severe diseases, VE of the first and second booster was 77.3% (61.2–86.7%) at [Formula: see text]90 days and 55.9% (23.4–74.6%) afterward.Conclusion mRNA booster vaccination provided moderate protection against symptomatic infections and high-level protection against severe diseases during the BA.5 epidemic in Japan.

Published
2024
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271. 28-country global study on associations between cultural characteristics and Recovery College fidelity

Author

Kotera, Yasuhiro, Ronaldson, Amy, Hayes, Daniel, Hunter-Brown, Holly, McPhilbin, Merly, Dunnett, Danielle, Jebara, Tesnime, Takhi, Simran, Masuda, Takahiko, Camacho, Elizabeth, Bakolis, Ioannis, Repper, Julie, Meddings, Sara, Stergiopoulos, Vicky, Brophy, Lisa, De Ruysscher, Clara, Okoliyski, Michail, Kubinová, Petra, Eplov, Lene, Toernes, Charlotte, Narusson, Dagmar, Tinland, Aurélie, Puschner, Bernd, Hiltensperger, Ramona, Lucchi, Fabio, Miyamoto, Yuki, Castelein, Stynke, Borg, Marit, Klevan, Trude Gøril, Tan Boon Meng, Roger, Sornchai, Chatdanai, Tiengtom, Kruawon, Farkas, Marianne, Moreland Jones, Hannah, Moore, Edith, Butler, Ann, Mpango, Richard, Tse, Samson, Kondor, Zsuzsa, Ryan, Michael, Zuaboni, Gianfranco, Elton, Dan, Grant-Rowles, Jason, McNaughton, Rebecca, Hanlon, Charlotte, Harcla, Claire, Vanderplasschen, Wouter, Arbour, Simone, Silverstone, Denise, Bejerholm, Ulrika, Powell, Candice, Ochoa, Susana, Garcia-Franco, Mar, Tolonen, Jonna, Yeo, Caroline, Charles, Ashleigh, Henderson, Claire, and Slade, Mike

Published
2024
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276. CXCL10 predicts autoimmune features and a favorable clinical course in patients with IIP: post hoc analysis of a prospective and multicenter cohort study

Author

Enomoto, Noriyuki, Nakai, Shogo, Yazawa, Shusuke, Mochizuka, Yasutaka, Fukada, Atsuki, Tanaka, Yuko, Naoi, Hyogo, Inoue, Yusuke, Yasui, Hideki, Karayama, Masato, Suzuki, Yuzo, Hozumi, Hironao, Furuhashi, Kazuki, Toyoshima, Mikio, Kono, Masato, Imokawa, Shiro, Fujii, Masato, Akamatsu, Taisuke, Koshimizu, Naoki, Yokomura, Koshi, Matsuda, Hiroyuki, Kaida, Yusuke, Nakamura, Yutaro, Shirai, Masahiro, Mori, Kazutaka, Masuda, Masafumi, Fujisawa, Tomoyuki, Inui, Naoki, Sugiura, Hiroaki, Sumikawa, Hiromitsu, Kitani, Masashi, Tabata, Kazuhiro, Ogawa, Noriyoshi, and Suda, Takafumi

Published
2024
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283. WONDER-02: plastic stent vs. lumen-apposing metal stent for endoscopic ultrasound-guided drainage of pancreatic pseudocysts—study protocol for a multicentre randomised non-inferiority trial

Author

Saito, Tomotaka, Takenaka, Mamoru, Kuwatani, Masaki, Doi, Shinpei, Ohyama, Hiroshi, Fujisawa, Toshio, Masuda, Atsuhiro, Iwashita, Takuji, Shiomi, Hideyuki, Hayashi, Nobuhiko, Iwata, Keisuke, Maruta, Akinori, Mukai, Tsuyoshi, Matsubara, Saburo, Hamada, Tsuyoshi, Inoue, Tadahisa, Matsumoto, Kazuyuki, Hirose, Sumio, Fujimori, Nao, Kashiwabara, Kosuke, Kamada, Hideki, Hashimoto, Shinichi, Shiratori, Toshiyasu, Yamada, Reiko, Kogure, Hirofumi, Nakahara, Kazunari, Ogura, Takeshi, Kitano, Masayuki, Yasuda, Ichiro, Isayama, Hiroyuki, and Nakai, Yousuke

Published
2024
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298. Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations

Author

Kaneko, Syuzo, Takasawa, Ken, Asada, Ken, Shiraishi, Kouya, Ikawa, Noriko, Machino, Hidenori, Shinkai, Norio, Matsuda, Maiko, Masuda, Mari, Adachi, Shungo, Takahashi, Satoshi, Kobayashi, Kazuma, Kouno, Nobuji, Bolatkan, Amina, Komatsu, Masaaki, Yamada, Masayoshi, Miyake, Mototaka, Watanabe, Hirokazu, Tateishi, Akiko, Mizuno, Takaaki, Okubo, Yu, Mukai, Masami, Yoshida, Tatsuya, Yoshida, Yukihiro, Horinouchi, Hidehito, Watanabe, Shun-Ichi, Ohe, Yuichiro, Yatabe, Yasushi, Saloura, Vassiliki, Kohno, Takashi, and Hamamoto, Ryuji

Published
2024
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