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Introduction: Congenital granular cell epulis is a rare and benign lesion in newborn. There are some papers of the entity; however, there are very few reports focusing on its macroscopic view. Case Presentation: A 0-day-old boy was noted to have a mass consisting of multiple nodules on maxillary gingiva, and it was excised. The mass was measured about 2 cm in its greatest diameter. Surface of cross-section was characteristically whitish-yellow and very smooth. Histopathologically, the lesion was composed of a proliferation of large polygonal cells with demarcated cell membrane, granular cytoplasm, and small uniform nuclei. Immunohistochemically, these cells were negative for S100. The diagnosis was concluded as congenital granular cell epulis. Discussion and Conclusion: We reported a typical case of congenital granular cell epulis. It is noteworthy that the cross-section observed in this case was very characteristically whitish-yellow and smooth.

Congenital granular cell epulis (CGCE) is an uncommon lesion of unclear pathogenesis. It occurs predominantly in female newborns with a predilection site of the maxillary alveolar ridge. The mass enlarges prenatally but the growth arrests after birth. Histologically, CGCE is characterized by a proliferation of polygonal cells with eosinophilic, granular cytoplasm and eccentric, bland-appearing nuclei. It closely resembles adult granular cell tumor (GCT) microscopically and S-100 immunostain is often helpful in distinguishing the two (S-100-positive in GCT and S-100-negative in CGCE). Clinically, the lesion should also be distinguished from entities such as infantile myofibroma, rhabdomyoma, melanotic neuroectodermal tumor of infancy, peripheral odontogenic fibroma, and neurofibroma. CGCE demonstrates an excellent prognosis and has not been associated with any syndromes/genetic defects or malignant transformation. Clinicians and pathologists should be familiar with this rare entity and its differential diagnosis for accurate diagnosis and management.

Background Oral focal mucinosis, the oral counterpart of cutaneous focal mucinosis, is a rare disease. As it has no characteristic clinical or radiological features, diagnosis is established by histopathological and immunohistological examination. We present three cases of oral focal mucinosis occurring in the retromolar (which is extremely rare) and gingival regions. Case presentation Case 1 involved a 26-year-old Japanese man with radiolucency in the right retromolar region on panoramic radiograph and computed tomography; no obvious protrusion was observed in the region. This finding was clinically diagnosed as a tumor of the retromolar region. Case 2 involved a 60-year-old Japanese woman. A tumor-like mass of tissue was identified on the buccal gingiva at the maxillary right canine and first premolar region. The lesion measured 7 × 6 mm and exhibited elastic hardness and healthy-colored mucosa. The lesion was diagnosed as an epulis. Case 3 involved a 47-year-old Japanese woman. A tumor-like mass of tissue was identified on the buccal gingiva at the maxillary right canine and first premolar region. The lesion measured 10 × 10 mm and exhibited elastic hardness and redness of the surface mucosa. This lesion was also diagnosed as an epulis. Resection was performed in all three cases, and the lesions were histopathologically diagnosed as oral focal mucinosis. Postoperative courses were uneventful and, thus far, there have been no recurrences. Conclusions Although it is difficult to diagnose oral focal mucinosis based on clinical symptoms and imaging findings, the disease should be considered a possibility when diagnosing benign oral tumors. We believe that an emphasis on histopathologic study is essential to confirm the clinical suspicion.

The epulis is a relatively frequent benign oral lesion that originates from the gingival and which has no degenerative potential. A 73-year-old-woman came to our attention for a mass, located in the oral cavity and more precisely in the right inferior maxillary alveolar ridge, that the patient firstly noticed 2 years earlier. Its dimensions increased over time and now were relevant. The mass was mobile, and non-ulcerated e did not evoke pain when palpated. It was characterized by a thin pedicle and its resection, under local anesthesia, allowed a complete removal of the mass itself. The histological examination showed a fibrous and plasmacellular epulis with calcific spots and mixoid aspects. We here report this case for the unique dimensions of this epulis and in order to give a useful example that could help in the differential diagnosis of the lesions located in the oral cavity.

Malignant melanoma of oral mucosa is a rare and fatal tumor that occurs exceptionally during pregnancy. Among one of the theories, several authors have discussed the possibility of mali- gnant transformation of a pigmented lesion of the oral mucosa to malignant melanoma during pregnancy. We report the case of a 30-years-old patient who consulted for an increasing volume of a pigmented lesion during pregnancy that the dentist has diagnosed as a pregnancy epulis. Clinical examination reveals the presence of bluish-black budding tume- faction. Histological and immune-histochemical examination confirmed the diagnosis of malignant melanoma of the palatal mucosa. Resume Le melanome malin de la muqueuse buccale est une tumeur rare et mortelle qui survient exceptionnellement pendant la gros- sesse. Parmi l’une des theories, plusieurs auteurs ont discute la possibilite de transformation maligne d’une lesion pigmentee de la muqueuse buccale en melanome malin pendant la grossesse. Nous rapportons le cas d’une patiente de 30 ans qui a consulte pour un accroissement en volume d’une lesion pigmentee pen- dant la grossesse que le dentiste a diagnostique epulis gravi- dique. L’examen clinique a revele la presence d’une tumefaction bleu-noirâtre d’aspect bourgeonnant. Les examens histologiques et immunohistochimiques ont confirme le diagnostic de mela- nome malin de la muqueuse palatine.

After provisional or definitive cementation of fixed implant-supported prostheses, spontaneous gingival proliferation may occur to fill the cervical embrasure areas of the prosthesis. Adequate oral hygiene, osseous spacing between the supporting implants and attached or immovable soft tissue may be the conditions that allow this phenomenon. This proliferation embrasure fill eliminates interproximal gingival voids, that is, black triangles, and makes the outcome more esthetically acceptable. Since interproximal prosthetic deign and implant positioning may be the primary factors for the fill, the gingival fill may be, in fact, an epulis.

Aim of the present study was clinical and histopathological evaluation of a series of epulides to provide clinicians data to frequency distribution and biological behaviour of different underlying entities. Ninety-two cases of epulides removed by CO2-laser at the Department of Oral Surgery and Radiology, Medical University of Graz from 2000 to 2014 were studied retrospectively for clinical data and histopathological diagnosis. In the presented study, histopathological examination revealed peripheral ossifying fibroma (32.6 %), fibroma/fibrosis (29.3 %), giant cell lesion (13.1 %) and granuloma pyogenicum (8.7 %) as the most frequent underlying entities. For the first time, hyperplastic squamous epithelium (7.6 %), granulation tissue (5.4 %) and peripheral odontogenic fibromas (3.3 %) were detected to clinically appear as epulides. Irrespective of the histological diagnosis, the mean age in our patients was 43.8 years. The majority of the lesions were found in the frontal region of both jaws. In all cases, the patients showed poor oral hygiene, local gingivitis and some of them an occlusal trauma. To identify different entities with different biological behaviour, to exclude malignant tumours and to identify new entities among epulides, histopathological examination is required. Poor oral hygiene and occlusal trauma seem to play an important role in the pathogenesis and could be risk factors for recurrences. Frequency distribution of different entities in epulides is provided to clinicians, and new histopathological entities were detected to clinically appear as epulides.

Introduction Congenital epulis or congenital granular cell tumour is a rare benign lesion arising from alveolar mucosa of neonates which can cause respiratory and feeding problems. It is also known as Neumann’s tumour. Females are affected 10 times more frequent. Method A review of medical record was performed. Result A newborn presented with lesion over left lower gum which was seen during antenatal abdominal ultrasonography scan by Obstetrics team at 35-week of gestation. The case was referred for ex utero intrapartum treatment procedure in view of anticipating upper airway obstruction. Upon delivery via Caesarean section, patient had no obstructive symptoms however was immediately intubated few hours of life to secure airway. Computed tomography scan confirmed a soft tissue mass arising from either lower alveolus or tip of tongue. The lesion was excised and histopathological examination reported as congenital epulis. Conclusion Even though it is a rare case, congenital epulis should be considered as one of differential diagnosis of an oral mass. A multi-disciplinary team management is important in view of possibility of upper airway obstruction post delivery.

Reports of neoplasia in captive reptiles are becoming more frequent; however, there is still scarce knowledge of the occurrence of neoplasia in wild reptiles. A wild black rat snake ( Pantherophis alleghaniensis) was presented to the Zoological Medicine service of the University of Georgia’s Veterinary Teaching Hospital with a 3 cm in diameter solid mandibular mass that was partially ulcerated. Radiographically, the mass was radiopaque with small bone spicules and partial osteolysis of the adjacent mandible. Histologic examination of the mass revealed a neoplasm composed of cuboidal to polygonal cells arranged in islands, anastomosing cords, and trabeculae of pseudostratified epithelium with a palisading peripheral layer of densely packed columnar cells with cytoplasmic clearing. The neoplastic tissue was separated from the mesenchyme by a prominent band of fine collagen. Neoplastic cells were positive for cytokeratin and negative for smooth muscle actin. Electron microscopy highlighted the presence of tonofilaments and microvilli. These findings led to the diagnosis of ameloblastoma, an odontogenic epithelial tumor known to occur in humans and most veterinary species.

Congenital granular cell epulis (CGCE) is an uncommon benign lesion found in newborns. It has predominance for females with an 8:1 ratio in relation to males and is exclusively encountered in the oral cavity. The most affected oral site is located around the canine/incisor region of the maxillary alveolar ridge, where the lesion arises from the soft tissue as a solitary pedunculated mass. CGCE's histogenesis remains obscure and controversial. We present a rare case of 2 separate CGCE lesions adjacent to each other measuring 23 × 18 × 10 and 15 × 10 mm, positioned facially on the right maxillary alveolar process. The patient, a 2-day-old female newborn, did not experience any serious difficulty regarding breathing or deglutition. Complete surgical excision was the treatment of choice in this case, and the procedure was performed under both general and local anesthesia. Histologic and immunohistochemical analysis confirmed the diagnosis of CGCE. The patient showed satisfactory postoperative healing and excellent health at both the 10-day recall appointment and the 6-month follow-up.

Epulis is a relatively common benign polypoid lesion that generally appears in the gingiva of individuals aged between 20 and 50 years. A 6-year-old Japanese girl came to our hospital for consultation regarding swelling of the marginal gingiva in the region between the maxillary left deciduous lateral incisor and canine. An intraoral examination revealed that the surface of the swollen mass was nonulcerated and smooth, and its color was similar to that of the surrounding gingival tissue. X-ray findings showed no calcified body or tooth germ malposition. The lesion was removed surgically under local anesthesia and histopathological findings showed it to be composed of fibrous connective tissue and blood vessels with minimal inflammatory cells, and covered by stratified squamous epithelium cells under the mucosa, which led to a diagnosis of epulis fibrosa. Patient prognosis has been good to date with no symptoms indicating recurrence.

Objectives Oral squamous cell carcinoma (OSCC) is the most common epithelial malignant neoplasm affecting the oral cavity. OSCC can mimic oral lesions of inflammatory origin with benign features, often leading to delay in diagnosis and treatment. Early detection is important to greatly increase the chances of a successful treatment. The present study reports a proteomic analysis of a gingival oral squamous cell carcinoma (G-OSCC) and an epulis. Materials and methods Normal mucosae tissue, G-OSCC tissue, and epulis tissue as a comparative sample of benign nature were collected and immediately frozen in liquid nitrogen. Tissue-extracted proteins were separated by two-dimensional gel electrophoresis and subjected to image analysis. Proteins that showed a significant difference in the expression level in the G-OSCC tissue were identified by the nano-ESI-HPLC-MS/MS experiment and database searchi. Results and conclusion The proteomic analysis of G-OSCC tissue enabled the identification of proteins that are potentially related to the disease; these proteins can be considered as signature molecules for diagnostic and prognostic tumor markers.

Six dogs with clinically and histologically confirmed epulis were included in this study Five dogs had a localized smooth non ulcerated oral mass protruded from the margins of either lower or upper lips whereas in one animal ulcerated diffuse and areas of necrosis located at lower jaw was seen During physical examination mass was detected in the oral cavity originated from the gums darkly pigmented varied in sizes and foul smelling All tumours were histologically benign except one Fibromatous and acanthomatous epulis were observed In one case distant pulmonary metastasis was confirmed radiologicaly Nitrous oxide cryoprobe was used in benign cases to excise these tumours under general anesthesia Nanosomal docetaxel was used as chemotherapy in one metastatic case Complete healing without any postoperative complications was observed in cryosurgery No recurrence was observed after six months of cryoablation Chemotherapy in metastatic epulis cases was found unsatisfactory It may be concluded that cryosurgery can be used for treatment of benign epulis in canines

In the oral cavity, several growths may occur, while some of these growths may be malignant, most of them tend to be benign. Even the benign lesions can be a big problem. Many are locally invasive and inclined to recur and their physical presence in the mouth can lead to traumatic occlusion and entrapment of debris, predisposing to infection. It is therefore of great importance that these growths be treated carefully with the elimination of the causative factors. The aim of this article is to present two such cases where benign pyogenic growths were misdiagnosed as malignant growth causing unnecessary stress and mental trauma to the patient.

A mucous cyst (mucous extravasation cyst, mucocele, ranula, mucous retention cyst) is a thin sac on the inner surface of the lips. They are painless swellings but can be bothersome. The cysts are thought to be caused because of trauma by sucking of the lip membranes between the teeth, if left untreated; they can organize and form a permanent bump on the inner surface of the lip. They are Case Study Agarwal et al.; BJMMR, 10(2): 1-5, 2015; Article no.BJMMR.15245 2 known as ranula when on the floor of the mouth, and epulis when present on the gums. This article highlights the advantages and evaluates the efficacy of treatment of mucocele with the help of diode lasers.

Background Gastric cancer rarely metastasizes to the oral cavity, especially to gingiva. Only 18 cases have been reported worldwide to date. This paper herein presents the nineteenth case of gingival metastasis from gastric cancer. Case presentation A 75-year-old man who underwent a radical gastrectomy for gastric adenocarcinoma was admitted to clinical oncology center for gingival mass which was originally diagnosed as epulis. The subsequent positron emission tomography-computed tomography (PET-CT) and histopathological examination revealed a gingival metastatic adenocarcinoma originated from gastric carcinoma. Then three-dimensional conformal radiotherapy (3D–CRT) with synchronization and sequential chemotherapy demonstrated clinical benefit in this patient. Furthermore, this research reviewed the records of 18 cases of gingival metastasis from gastric carcinoma in English, Japanese, and Chinese literature, and summarized the clinicopathologic features of the disease based on previously published papers. Conclusion This case suggests that gingival metastasis from gastric cancer is worthy of vigilance. Biopsy and immunohistochemical (IHC) staining should be used for the final diagnosis. Moreover, the patient with uncommon gingival metastatic lesion can be successfully treated by radiotherapy with adjuvant chemotherapy.

The work consists of 41 pages, 25 pictures, 48 references were used. The aim of this study: to evaluate the incidence of canine and feline epulides. The tasks: to findout what part of all gingival pathologies consists epulides, to find out if dog or cats more ofen has epulides, to asses the predisposition of sex, age and breed, and to find out the most common types of epulides diagnosed for cats and dogs. Methods: the gingival hyperplasias were also counted as epulides. 4 feline and 2 canine gingival samples were collected at private small animal clinic in Kaunas between 2015 – 2016 years and 6 feline and 18 canine gingival samples were evaluated from LUHS Veterinary academy Pathology center archivied during 2012 – 2016 years. 10 feline and 20 canine gingival samples were evaluated during this study. Conclusions: the study showed that epulides were diagnosed 58,33 % of canine gingival samples and 42,86 % of feline gingival masses. Epulides were most commonly diagnosed for dogs, most commonly for males. 58,33 % of canine epulides were diagnosed from 6 to 9 years old dogs, 50 % of feline epulides were diagnosed for from 4 to 6 years old cats. There was no breed predisposition for dogs, among cats, the epulides were the most common diagnosed in mixed breed cats. The study showed that 71,4 % of canine epulides were fibromatous epulides, 14,3 % were gingival hyperplasias, acantomateus and ossifying epulides contained at 7,14 % each. For cats, the most common diagnosed types of epulides were gingival hyperplasia (66,7 %) and fibromatous epulides (33,33 %), the multiple feline epulides, identified as fibromatous epulides, were diagnosed for 1 cat.

Mouth metastatic cancers are very rare and they usually represent the evidence of a widespread disease. Common primary tumors are lung carcinoma in men and breast carcinoma in women, followed by kidney cancer. In the oral soft tissues, the gingiva is the most common site, suggesting a possible role of inflammation in the attraction of circulating tumor cells. Oral metastasis has a serious prognosis. In this work, we describe the case of a 58-year-old man affected by renal cancer, who was brought to our attention for the appearance of a gingival swelling. Initially, the lesion was excised through a provisional clinical diagnosis of epulis. Subsequently, anatomopathological analysis showed a metastasis compatible with clear-cell carcinoma and specifically its renal origin was confirmed by immunohistochemical techniques., SCOPUS: ar.j, info:eu-repo/semantics/published

Epulis is a benign hyperplasia of the oral soft tissues. Surgical excision always extends to the periosteum and includes scaling of adjacent teeth to remove any possible irritants. The esthetics of the soft tissues may be compromised, however. This article studies three cases in which an immediate laterally positioned flap (LRF) was used to repair mucogingival defects after epulis biopsies. After 24 months, the color and shape of the surgical areas were healthy and stable, nearly complete root coverage was evident, and no lesions reoccurred. For repairing gingival defects after biopsy, LRF appears to be minimally traumatic while promoting esthetic outcomes.

Congenital epulis is an uncommon benign lesion that affects the oral cavity of newborns, and presents histological features which are similar to those of granular cell tumor. The origin of this lesion has not been fully elucidated, and many hypotheses are considered due to the large variety of cell types observed in histological sections. Epulis development occurs further in the prenatal period, and is more common in newborn females, frequently in the maxilla. This lesion usually is presentend as a nodule covered by normal oral mucosa, which in some cases, interferes with baby's breathing and feeding. This report describes the case of a two-month-old male baby who presented a pedunculated intraoral lesion in the mandibular alveolar ridge. Histological sections revealed presence of mucosal fragments with atrophic squamous stratified epithelium, and fibrous connective tissue composed of cells with granular and eosinophilic cytoplasm. A few days after initial exam, the lesion detached from alveolar ridge, and healed spontaneously.

Tumor, tumor-like diseases of the oral cavity diverse. In the literature cases of these diseases, however, there are contradictions in the notes on the frequency of occurrence, gender differences, the structure of injury, and a description of such diseases in one study missing.

Leiomyosarcoma of the oral cavity is a very rare tumor type associated with aggressive clinical behavior and a low survival rate. However, this tumor may also be encountered as a slow-growing, non-ulcerated, painless mass in its early stage. We report a case of leiomyosarcoma, affecting the gingival mucosa of a 24-year-old male. The tumor mimicked an epulis, because it was encountered as a slow-growing, discreet, firm, non-ulcerated, painless mass without any evidence of resorption of the maxillary bone. Excision of the “epulis” resulted in a histological diagnosis of leiomyosarcoma. The histological findings of a wider excision did not indicate the presence of any tumor cells. The patient has since remained tumor-free for 3 years. A literature review, related to the gingiva of the maxilla or mandible, indicated only a few cases wherein the tumor behavior was similarly mild and benign as it was in this case. Thus, when the tumor is diagnosed at an early stage, while it is small and non-aggressive, successful treatment can lead to a good prognosis.

Introduction: Plasmablastic lymphoma is a high-grade life-threatening immunologic malignancy most often found in patients with human immunodeficiency virus (HIV). It is regarded as a unique AIDS-related lymphoma that has been described in individuals without HIV. Intraoral presentation in such circumstances is extremely rare. CasePresentation:Apatientpresentedwithaninnocuousepulisandchronicperiodontitis.Thepatienthadahistory of renal transplant and long-term immunosuppression with cyclosporine. The localized area of gingival enlargement, although provisionally diagnosed as gingival disease modified by medication, was excised and subsequently confirmed as an acute plasmablastic lymphoma. Excised tissue was sent off for routine histopathologic examination. Latent membrane proteins were found for Epstein-Barr virus. Atypical lymphoid tissue with multiple immune markers was indicative of a plasmablastic plasmacytoma,butthisdiagnosiswasmodifiedin lightofthehistory ofimmunosuppressionandpositiveEpsteinBarr markers to a post-transplant plasmablastic lymphoma. The patient was managed with a combination of chemotherapy and radiotherapy. The patient is now posttreatment, and there are no signs of recurrence or metastasis. Conclusions:Thisisararepresentation.Toourknowledge,therehavebeen

Objective This study evaluated the percentage of cases correctly identified as epulis fissuratum based on the clinical impression and histopathologic diagnosis and evaluated the percentage of cases identified as a malignancy by the histopathologic diagnosis with a clinical impression of epulis fissuratum. Findings A search in the database systems at the biopsy services of University of Nebraska Medical Center College of Dentistry and Tufts University School of Dental Medicine for the clinical impression term epulis/epulis fissuratum from January 1, 2012 until July 1, 2017 was performed which identified 187 cases. The Fisher's exact test measured the similarity between dental practitioners’ clinical impression of epulis fissuratum and histopathologic findings. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the dental practitioners’ clinical impression about the malignancy of epulis fissuratum were calculated. P value Conclusion Based on the collected data, dental practitioners should remove and submit excised tissue for microscopic analysis to rule out malignancy in suspected cases of epulis fissuratum.

Congenital epulis is a rare congenital tumor affecting the oral mucosa. It is usually seen in females and has no known syndromic association. It may cause the interference to feeding or airway obstruction, thus presenting as an emergency. Visually, it causes a lot of undue stress and anxiety to the parents and relatives. Multiple epulis occurs only in 10% of cases. Recurrence of the tumor, malignant change, or damage to dentition is not seen post-excision. Clinicians, particularly those working in the tertiary health care facilities, should be aware of this benign and easily treatable tumor of the neonate. Key words: Epulis, Gingival tumor, Granular cell tumor, Neumann’s tumor

Congenital granular cell epulis is a rarely reported lesion of unknown histogenesis with a strong predilection for the maxillary alveolar ridge of newborn girls. Microscopically, it demonstrates nests of polygonal cells with granular cytoplasm, a prominent capillary network, and attenuated overlying squamous epithelium. The lesion lacks immunoreactivity for S-100, laminin, chromogranin, and most other markers except neuron-specific enolase and vimentin. Through careful observation of its unique clinical, histopathologic, and immunohistochemical features, this lesion can be distinguished from the more common adult granular cell tumor as well as other differential diagnoses.

Uterine leiomyosarcoma (LMS) is a rare tumor constituting 1% of all uterine malignancies. This sarcoma demonstrates an aggressive growth pattern with an high rate of recurrence with hematologic dissemination; the most common sites are lung, liver, and peritoneal cavity, head and neck district being rarely interested. Only other four cases of metastasis in the oral cavity have been previously described. The treatment of choice is surgery and the use of adjuvant chemotherapy and radiation has limited impact on clinical outcome. In case of metastases, surgical excision can be performed considering extent of disease, number and type of distant lesions, disease free interval from the initial diagnosis to the time of metastases, and expected life span. We illustrate a case of uterine LMS metastasis in the upper buccal gingiva that occurred during chemotherapy in a 63-year-old woman that underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy for a diagnosis of LMS staged as pT2bN0 and that developed lung metastases eight months after primary treatment. Surgical excision of the oral mass (previously misdiagnosed as epulis at a dental center) and contemporary reconstruction with pedicled temporalis muscle flap was performed in order to improve quality of life. Even if resection was achieved in free margins, “local” relapse was observed 5 months after surgery.

Plasma cell granuloma is a non-neoplastic lesion rather uncommonly seen in the maxillofacial region. Its etiology, biological behavior, ideal treatment and prognosis are still unclear and rather controversial.A detailed histopathological examination and immunohistochemical study of the excised specimen was carried out, both for making a confirmatory diagnosis as well as to determine the etiopathology, biological behavior and prognosis of the lesion.Light microscopy revealed a hyperplastic stratified squamous epithelial lining, overlying a densely fibrocellular granulation tissue containing a rich proliferation of mononuclear inflammatory cells, among which there was a predominance of plasma cells with their typical eccentric, cartwheel shaped, "clock-faced" nuclei. Strong immunohistochemical positivity was observed for CD-138 by numerous cells of the connective tissue of the lesion, thus confirming them to indeed be plasma cells. Further, immunohistochemistry (IH) analysis also demonstrated the expression of both, the lambda and kappa light chain immunoglobulins by the plasma cell population, thus confirming them to be polyclonal and of an inflammatory, non-neoplastic origin.As a plasma cell granuloma is rarely encountered in the oral and maxillofacial region, its diagnosis could have been very easily missed, had it not been for the detection of the large numbers of plasma cells by light microscopy, which was further confirmed by IH. IH also helped in establishing the likely etiopathology of the lesion and confirmed it to be of a non-neoplastic reactive/inflammatory origin.

Odontogenic neoplasms are locally invasive oral tumors in dogs. The purpose of this retrospective study was to describe CT characteristics for varying histopathologic types of canine odontogenic neoplasms. A board-certified veterinary radiologist who was unaware of histologic findings reviewed and scored imaging studies. A total of 29 dogs were included in the study. Twenty-three of these dogs had concurrent dental radiographs. The most common CT characteristics for all tumor types were a direct association with or in the region of multiple teeth in 96.4% (27/28), contrast enhancement in 96.3% (26/27), alveolar bone lysis in 93.1% (27/29), and mass-associated tooth displacement in 85.2% (23/27). Mass-associated cyst-like structures were identified in 53.6% (15/28) and were only present in tumors containing odontogenic epithelium. Canine acanthomatous ameloblastomas (n = 15) appeared as extra-osseous (10/15) or intra-osseous (5/15) masses. Intra-osseous canine acanthomatous ameloblastomas were more likely to have mass-associated cyst-like structures and were subjectively more aggressive when compared with extra-osseous canine acanthomatous ameloblastomas. Amyloid-producing odontogenic tumors (n = 3) had subjectively uniform CT imaging characteristics and consisted of round soft tissue and mineral attenuating masses with multiple associated cyst-like structures. Fibromatous epulides of periodontal ligament origin (n = 4) were contrast enhancing extra-osseous masses that were rarely referred for CT examinations and 25% (1/4) were not visible with CT. Other odontogenic tumors were less represented or had more variable CT imaging characteristics. Mass-associated tooth destruction was appreciated more often with dental radiographs and extra-oral tumor extension was identified more often with CT.

Objectives/Hypothesis Congenital granular cell tumor (CGCT), also known as congenital epulis, is a rare benign mesenchymal tumor of the oral cavity. We report of a 3 years and 7 months old female patient undergoing surgical excision of an oral tumor. Subsequent histological and immunohistological investigations within the clinical course led to the diagnosis of CGCT. However, clinical findings in this case, such as primary onset and an untypical location within the oral cavity, clearly stand in contrast to those usually found in CGCT, resulting in an exceptional case not previously described in the literature. Laryngoscope, 123:2459–2462, 2013