1,269 results on '"de Leeuw, Frank-Erik"'
Search Results
202. Cerebral White Matter Lesions and Lacunar Infarcts Contribute to the Presence of Mild Parkinsonian Signs
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de Laat, Karlijn F., van Norden, Anouk G.W., Gons, Rob A.R., van Uden, Inge W.M., Zwiers, Marcel P., Bloem, Bastiaan R., van Dijk, Ewoud J., and de Leeuw, Frank-Erik
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- 2012
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203. Diffusion Tensor Imaging of the Hippocampus and Verbal Memory Performance: The RUN DMC Study
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van Norden, Anouk G.W., de Laat, Karlijn F., Fick, Ilma, van Uden, Inge W.M., van Oudheusden, Lucas J.B., Gons, Rob A.R., Norris, David G., Zwiers, Marcel P., Kessels, Roy P.C., and de Leeuw, Frank-Erik
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- 2012
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204. Frontal and Temporal Microbleeds Are Related to Cognitive Function: The Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Cohort (RUN DMC) Study
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van Norden, Anouk G.W., van den Berg, Heleen A.C., de Laat, Karlijn F., Gons, Rob A.R., van Dijk, Ewoud J., and de Leeuw, Frank-Erik
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- 2011
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205. Routine Use of the Confusion Assessment Method for the Intensive Care Unit: A Multicenter Study
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van Eijk, Maarten M., van den Boogaard, Mark, van Marum, Rob J., Benner, Paul, Eikelenboom, Piet, Honing, Marina L., van der Hoven, Ben, Horn, Janneke, Izaks, Gerbrand J., Kalf, Annette, Karakus, Attila, Klijn, Ine A., Kuiper, Michael A., de Leeuw, Frank-Erik, de Man, Tjarda, van der Mast, Roos C., Osse, Robert-Jan, de Rooij, Sophia E., Spronk, Peter E., van der Voort, Peter H., van Gool, Willem A., and Slooter, Arjen J.
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- 2011
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206. Cigarette smoking is associated with reduced microstructural integrity of cerebral white matter
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Gons, Rob A. R., van Norden, Anouk G. W., de Laat, Karlijn F., van Oudheusden, Lucas J. B., van Uden, Inge W. M., Zwiers, Marcel P., Norris, David G., and de Leeuw, Frank-Erik
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- 2011
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207. Microbleeds Are Independently Related to Gait Disturbances in Elderly Individuals With Cerebral Small Vessel Disease
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de Laat, Karlijn F., van den Berg, Heleen A.C., van Norden, Anouk G.W., Gons, Rob A.R., Olde Rikkert, Marcel G.M., and de Leeuw, Frank-Erik
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- 2011
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208. Diffusion Tensor Imaging and Gait in Elderly Persons With Cerebral Small Vessel Disease
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de Laat, Karlijn F., van Norden, Anouk G.W., Gons, Rob A.R., van Oudheusden, Lucas J.B., van Uden, Inge W.M., Norris, David G., Zwiers, Marcel P., and de Leeuw, Frank-Erik
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- 2011
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209. Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease
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de Laat, Karlijn F., Tuladhar, Anil M., van Norden, Anouk G. W., Norris, David G., Zwiers, Marcel P., and de Leeuw, Frank-Erik
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- 2011
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210. Post-Stroke Working Memory Dysfunction: A Meta-Analysis and Systematic Review
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Lugtmeijer, Selma, primary, Lammers, Nikki A., additional, de Haan, Edward H. F., additional, de Leeuw, Frank-Erik, additional, and Kessels, Roy P. C., additional
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- 2020
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211. Multi-shell Diffusion MRI Models for White Matter Characterization in Cerebral Small Vessel Disease
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Konieczny, Marek J., primary, Dewenter, Anna, additional, ter Telgte, Annemieke, additional, Gesierich, Benno, additional, Wiegertjes, Kim, additional, Finsterwalder, Sofia, additional, Kopczak, Anna, additional, Hübner, Mathias, additional, Malik, Rainer, additional, Tuladhar, Anil M., additional, Marques, José P., additional, Norris, David G., additional, Koch, Alexandra, additional, Dietrich, Olaf, additional, Ewers, Michael, additional, Schmidt, Reinhold, additional, de Leeuw, Frank-Erik, additional, and Duering, Marco, additional
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- 2020
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212. Serum Neurofilament Light Chain Is Associated with Incident Lacunes in Progressive Cerebral Small Vessel Disease
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Peters, Nils, primary, van Leijsen, Esther, additional, Tuladhar, Anil M., additional, Barro, Christian, additional, Konieczny, Marek J., additional, Ewers, Michael, additional, Lyrer, Philippe, additional, Engelter, Stefan T., additional, Kuhle, Jens, additional, Duering, Marco, additional, and de Leeuw, Frank-Erik, additional
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- 2020
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213. Apathy, but not depression, predicts all-cause dementia in cerebral small vessel disease
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Tay, Jonathan, primary, Morris, Robin G, additional, Tuladhar, Anil M, additional, Husain, Masud, additional, de Leeuw, Frank-Erik, additional, and Markus, Hugh S, additional
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- 2020
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214. Temporal Dynamics of Cortical Microinfarcts in Cerebral Small Vessel Disease
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ter Telgte, Annemieke, primary, Wiegertjes, Kim, additional, Gesierich, Benno, additional, Baskaran,, Brendon Sri, additional, Marques, José P., additional, Kuijf, Hugo J., additional, Norris, David G., additional, Tuladhar, Anil M., additional, Duering, Marco, additional, and de Leeuw, Frank-Erik, additional
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- 2020
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215. Network neuroscience of apathy in cerebrovascular disease
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Tay, Jonathan, primary, Lisiecka-Ford, Danuta M., additional, Hollocks, Matthew J., additional, Tuladhar, Anil M., additional, Barrick, Thomas R., additional, Forster, Anne, additional, O’Sullivan, Michael J., additional, Husain, Masud, additional, de Leeuw, Frank-Erik, additional, Morris, Robin G., additional, and Markus, Hugh S., additional
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- 2020
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216. Ischaemic stroke in young adults: a global perspective
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Boot, Esther, primary, Ekker, Merel Sanne, additional, Putaala, Jukka, additional, Kittner, Steven, additional, De Leeuw, Frank-Erik, additional, and Tuladhar, Anil M, additional
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- 2020
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217. Vascular reserve in brain resilience: pipes or perfusion?
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Wiesmann, Maximilian, primary and de Leeuw, Frank-Erik, additional
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- 2020
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218. Abstract 152: Genome-wide Association Study of Early-Onset Ischemic Stroke Identifies Novel Locus on Chromosome 12 Near BCL7A/MLXIP
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Jaworek, Thomas, primary, Kittner, Steven J, additional, Jern, Christina, additional, de Leeuw, Frank Erik, additional, Dichgans, Martin, additional, Malik, Rainer, additional, Fernandez, Israel, additional, Slowik, Agnieszka, additional, Boncoraglio, Giorgio Boncoraglio, additional, Lindgren, Arne, additional, Jimenez-Conde, Jordi, additional, Schmidt, Reinhold, additional, Sharma, Pankah, additional, Lemmens, Robin, additional, Melander, Olle, additional, Rothwell, Peter, additional, Levi, Christopher, additional, Sudlow, Catherine, additional, Debette, Stephanie, additional, Howson, Joanna, additional, Pare, Guillaume, additional, Markus, Hugh, additional, Salaheen, Danish, additional, Zand, Ramin, additional, Worrall, Brad, additional, Meschia, James, additional, Rundek, Tatjana, additional, Woo, Dan, additional, Lee, Jin-Moo, additional, Irvin, Ryan, additional, Rexrode, Kathyn, additional, Smoller, Sylvia, additional, Rosand, Jonathan, additional, Mueller, Martina, additional, and Salomaa, Veikko, additional
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- 2020
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219. Structural network efficiency predicts cognitive decline in cerebral small vessel disease
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Boot, Esther M., primary, MC van Leijsen, Esther, additional, Bergkamp, Mayra I., additional, Kessels, Roy P.C., additional, Norris, David G., additional, de Leeuw, Frank-Erik, additional, and Tuladhar, Anil M., additional
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- 2020
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220. Hypertension and Cerebral Diffusion Tensor Imaging in Small Vessel Disease
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Gons, Rob A.R., de Laat, Karlijn F., van Norden, Anouk G.W., van Oudheusden, Lucas J.B., van Uden, Inge W.M., Norris, David G., Zwiers, Marcel P., and de Leeuw, Frank-Erik
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- 2010
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221. Patterns of Cortical Degeneration in an Elderly Cohort With Cerebral Small Vessel Disease
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Reid, Andrew T., van Norden, Anouk G.W., de Laat, Karlijn F., van Oudheusden, Lucas J.B., Zwiers, Marcel P., Evans, Alan C., de Leeuw, Frank-Erik, and Kötter, Rolf
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- 2010
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222. Gait in Elderly With Cerebral Small Vessel Disease
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de Laat, Karlijn F., van Norden, Anouk G.W., Gons, Rob A.R., van Oudheusden, Lucas J.B., van Uden, Inge W.M., Bloem, Bastiaan R., Zwiers, Marcel P., and de Leeuw, Frank-Erik
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- 2010
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223. Poststroke dementia—whatʼs in a name?
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Tuladhar, Anil M. and de Leeuw, Frank-Erik
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- 2010
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224. Parkinson disease and comorbid cerebrovascular disease
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Nanhoe-Mahabier, Wandana, de Laat, Karlijn F., Visser, Jasper E., Zijlmans, Jan, de Leeuw, Frank-Erik, and Bloem, Bastiaan R.
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- 2009
225. Treatment of Axial Mobility Deficits in Movement Disorders
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Bloem, Bastiaan, primary, De Leeuw, Frank-Erik, additional, and Orhan, Elif, additional
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- 2005
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226. Reduced medial temporal lobe functionality in stroke patients: a functional magnetic resonance imaging study
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Snaphaan, Liselore, Rijpkema, Mark, van Uden, Inge, Fernández, Guillén, and de Leeuw, Frank-Erik
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- 2009
227. Post-stroke depression: systematic review on pre- and post-stroke clinical and neuroimaging correlates
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Snaphaan, Liselore and de Leeuw, Frank-Erik
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- 2009
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228. Disruption of rich club organisation in cerebral small vessel disease
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Tuladhar, Anil M., Lawrence, Andrew, Norris, David G., Barrick, Thomas R., Markus, Hugh S., de Leeuw, Frank-Erik, and Magnetic Detection and Imaging
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Neuroinformatics ,Diffusion tensor imaging ,Diffusion Tensor Imaging ,Rich club organization ,Structural networks ,Medizin ,Cerebral small vessel disease ,structural networks ,graph-theory ,Graph-theory ,Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3] ,150 000 MR Techniques in Brain Function ,rich club organisation - Abstract
Contains fulltext : 170472.pdf (Publisher’s version ) (Open Access) Cerebral small vessel disease (SVD) is an important cause of vascular cognitive impairment. Recent studies have demonstrated that structural connectivity of brain networks in SVD is disrupted. However, little is known about the extent and location of the reduced connectivity in SVD. Here they investigate the rich club organisation-a set of highly connected and interconnected regions-and investigate whether there is preferential rich club disruption in SVD. Diffusion tensor imaging (DTI) and cognitive assessment were performed in a discovery sample of SVD patients (n = 115) and healthy control subjects (n = 50). Results were replicated in an independent dataset (49 SVD with confluent WMH cases and 108 SVD controls) with SVD patients having a similar SVD phenotype to that of the discovery cases. Rich club organisation was examined in structural networks derived from DTI followed by deterministic tractography. Structural networks in SVD patients were less dense with lower network strength and efficiency. Reduced connectivity was found in SVD, which was preferentially located in the connectivity between the rich club nodes rather than in the feeder and peripheral connections, a finding confirmed in both datasets. In discovery dataset, lower rich club connectivity was associated with lower scores on psychomotor speed (beta = 0.29, P < 0.001) and executive functions (beta = 0.20, P = 0.009). These results suggest that SVD is characterized by abnormal connectivity between rich club hubs in SVD and provide evidence that abnormal rich club organisation might contribute to the development of cognitive impairment in SVD. Hum Brain Mapp 38:1751-1766, 2017. (c) 2017 Wiley Periodicals, Inc.
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- 2017
229. Post-Stroke Depressive Symptoms Are Associated with Post-Stroke Characteristics
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Snaphaan, Liselore, van der Werf, Sieberen, Kanselaar, Karin, and de Leeuw, Frank-Erik
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- 2009
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230. Endovascular Thrombectomy in Young Patients With Stroke: A MR CLEAN Registry Study.
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Brouwer, Josje, Smaal, Johanna A., Emmer, Bart J., de Ridder, Inger R., van den Wijngaard, Ido R., de Leeuw, Frank-Erik, Hofmeijer, Jeannette, van Zwam, Wim H., Martens, Jasper M., Roos, Yvo B.W.E.M., Majoie, Charles B., van Oostenbrugge, Robert J., Coutinho, Jonathan M., and MR CLEAN Registry Investigators†
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- 2022
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231. Prediction of dementia using diffusion tensor MRI measures: the OPTIMAL collaboration.
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Egle, Marco, Hilal, Saima, Tuladhar, A. M., Pirpamer, Lukas, Hofer, Edith, Duering, Marco, Wason, James, Morris, Robin G., Dichgans, Martin, Schmidt, Reinhold, Tozer, Daniel, Chen, Christopher, de Leeuw, Frank-Erik, and Markus, Hugh S.
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BRAIN ,CEREBRAL small vessel diseases ,RESEARCH ,RESEARCH methodology ,MAGNETIC resonance imaging ,COGNITION ,MEDICAL cooperation ,EVALUATION research ,COMPARATIVE studies ,DEMENTIA ,LONGITUDINAL method - Abstract
Objectives: It has been suggested that diffusion tensor imaging (DTI) measures sensitive to white matter (WM) damage may predict future dementia risk not only in cerebral small vessel disease (SVD), but also in mild cognitive impairment. To determine whether DTI measures were associated with cognition cross-sectionally and predicted future dementia risk across the full range of SVD severity, we established the International OPtimising mulTImodal MRI markers for use as surrogate markers in trials of Vascular Cognitive Impairment due to cerebrAl small vesseL disease collaboration which included six cohorts.Methods: Among the six cohorts, prospective data with dementia incidences were available for three cohorts. The associations between six different DTI measures and cognition or dementia conversion were tested. The additional contribution to prediction of other MRI markers of SVD was also determined.Results: The DTI measure mean diffusivity (MD) median correlated with cognition in all cohorts, demonstrating the contribution of WM damage to cognition. Adding MD median significantly improved the model fit compared to the clinical risk model alone and further increased in all single-centre SVD cohorts when adding conventional MRI measures. Baseline MD median predicted dementia conversion. In a study with severe SVD (SCANS) change in MD median also predicted dementia conversion. The area under the curve was best when employing a multimodal MRI model using both DTI measures and other MRI measures.Conclusions: Our results support a central role for WM alterations in dementia pathogenesis in all cohorts. DTI measures such as MD median may be a useful clinical risk predictor. The contribution of other MRI markers varied according to disease severity. [ABSTRACT FROM AUTHOR]- Published
- 2022
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232. Determinants of extended door-to-needle time in acute ischemic stroke and its influence on in-hospital mortality: Results of a nationwide Dutch clinical audit
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Kuhrij, Laurien S., Marang-van de Mheen, Perla J., van den Berg-Vos, Renske M., de Leeuw, Frank-Erik, Nederkoorn, Paul J., Lingsma, H. F., de Borst, G. J., van Norden, A. G. W., Eysink Smeets, M. M., Aerden, L. A. M., Alblas, C. L., de Beer, F., Bienfait, H. P., Boon, A. E., Bor, S., Boreas, A. M. H. P., Bronner, I., Brouns, R., Brouwers, P. J. A. M., Brugman, F., Dane, M. L., Fransen, P. S. S., van Gemert, H. M. A., van Golde, A. E. L., de Graaf, M. T., Hani, L., van der Heijden, A. M. H. G., Hilkens, P. H., ten Holter, J. B. M., de Jong, S. W., Kapelle, L. J., Keizer, K., Keunen, R., Kloppenborg, R. P., Kok, A. J. M., Koops, L., Kruyt, N. D., de Leeuw, F. E., Lövenich, H., Luijckx, G. J., Maasland, E., Miedema, I., Nederkoorn, P. J., Persoon, S., Peters, E. W., van der Ree, T. C., Rozeman, A. D., Saxena, R., van Schaik, S., de Schryver, E. L. L. M., Schuiling, W. J., Schut, E. S., Staals, J. E. A., Stalpers, X., Tjeerdsma, H., van Tuijl, J. H., Vermeer, S. E., Visser, M. C., van den Wijngaard, I., van Zagten, M. S. G., Zylicz, S. A., Graduate School, ACS - Atherosclerosis & ischemic syndromes, Amsterdam Neuroscience - Neurovascular Disorders, Neurology, RS: Carim - B05 Cerebral small vessel disease, Klinische Neurowetenschappen, MUMC+: MA Med Staf Spec Neurologie (9), and RS: CARIM - R3.03 - Cerebral small vessel disease
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Clinical audit ,Male ,medicine.medical_specialty ,Percentile ,Neurology ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Logistic regression ,lcsh:RC346-429 ,Time-to-Treatment ,03 medical and health sciences ,0302 clinical medicine ,All institutes and research themes of the Radboud University Medical Center ,Internal medicine ,medicine ,Humans ,Neurochemistry ,Thrombolytic Therapy ,Quality improvement ,Stroke ,lcsh:Neurology. Diseases of the nervous system ,Aged ,Netherlands ,Aged, 80 and over ,business.industry ,General Medicine ,Thrombolysis ,Middle Aged ,medicine.disease ,Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3] ,3. Good health ,Female ,Neurology (clinical) ,Neurosurgery ,INTRAVENOUS THROMBOLYSIS ,business ,030217 neurology & neurosurgery ,Research Article - Abstract
Background Intravenous thrombolysis (IVT) plays a prominent role in the treatment of acute ischemic stroke (AIS). The sooner IVT is administered, the higher the odds of a good outcome. Therefore, registering the in-hospital time to treatment with IVT, i.e. the door-to-needle time (DNT), is a powerful way to measure quality improvement. The aim of this study was to identify determinants that are associated with extended DNT. Methods Patients receiving IVT in 2015 and 2016 registered in the Dutch Acute Stroke Audit were included. DNT and onset-to-door time (ODT) were dichotomized using the median (i.e. extended DNT) and the 90th percentile (i.e. severely extended DNT). Logistic regression was performed to identify determinants associated with (severely) extended DNT/ODT and its effect on in-hospital mortality. A linear model with natural spline was used to investigate the association between ODT and DNT. Results Included were 9518 IVT treated patients from 75 hospitals. Median DNT was 26 min (IQR 20–37). Determinants associated with a higher likelihood of extended DNT were female sex (OR 1.17, 95% CI 1.05–1.31) and admission during off-hours (OR 1.12, 95% CI 1.01–1.25). Short ODT correlated with longer DNT, whereas longer ODT correlated with shorter DNT. Young age (OR 1.38, 95% CI 1.07–1.76) and admission to a comprehensive stroke center (OR 1.26, 1.10–1.45) were associated with severely extended DNT, which was associated with in-hospital mortality (OR 1.54, 95%CI 1.19–1.98). Conclusions Even though DNT in the Netherlands is short compared to other countries, lowering the DNT may be achievable by focusing on specific subgroups.
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- 2019
233. Hippocampal volume and subcortical white matter lesions in late life depression: comparison of early and late onset depression
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Janssen, Joost, Pol, Hilleke E Hulshoff, de Leeuw, Frank-Erik, Schnack, Hugo G, Lampe, Indrag K, Kok, Rob M, Kahn, Rene S, and Heeren, Thea J
- Published
- 2007
234. Poststroke Memory Function in Nondemented Patients: A Systematic Review on Frequency and Neuroimaging Correlates
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Snaphaan, Liselore and de Leeuw, Frank-Erik
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- 2007
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235. Brain Imaging in Patients With Diabetes: A systematic review
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VAN HARTEN, BARBERA, DE LEEUW, FRANK-ERIK, WEINSTEIN, HENRY C., SCHELTENS, PHILIP, and BIESSELS, GEERT JAN
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- 2006
236. White Matter Lesions Are Associated With Progression of Medial Temporal Lobe Atrophy in Alzheimer Disease
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de Leeuw, Frank-Erik, Korf, Esther, Barkhof, Frederik, and Scheltens, Philip
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- 2006
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237. LOW VITAMIN B6 LEVELS ARE ASSOCIATED WITH WHITE MATTER LESIONS IN ALZHEIMERʼS DISEASE
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Mulder, Cees, Scheltens, Philip, Barkhof, Frederik, Gundy, Chad, Verstraeten, Rob A., and de Leeuw, Frank-Erik
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- 2005
238. Hippocampal changes and white matter lesions in early-onset depression
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Janssen, Joost, Hulshoff Pol, Hilleke E., Lampe, Indrag K., Schnack, Hugo G., de Leeuw, Frank-Erik, Kahn, Rene S., and Heeren, Thea J.
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- 2004
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239. Large expert-curated database for benchmarking document similarity detection in biomedical literature search
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Brown, Peter, Zhou, Yaoqi, Tan, Aik-Choon, El-Esawi, Mohamed A., Liehr, Thomas, Blanck, Oliver, Gladue, Douglas P., Almeida, Gabriel M.F., Cernava, Tomislav, Sorzano, Carlos O., Yeung, Andy W.K., Engel, Michael S., Chandrasekaran, Arun R., Muth, Thilo, Staege, Martin S., Daulatabad, Swapna V., Widera, Darius, Zhang, Junpeng, Meule, Adrian, Honjo, Ken, Pourret, Olivier, Yin, Cong-Cong, Zhang, Zhongheng, Cascella, Marco, Flegel, Willy A., Goodyear, Carl S., van Raaij, Mark J., Bukowy-Bieryllo, Zuzanna, Campana, Luca G., Kurniawan, Nicholas A., Lalaouna, David, Hüttner, Felix J., Ammerman, Brooke A., Ehret, Felix, Cobine, Paul A., Tan, Ene-Choo, Han, Hyemin, Xia, Wenfeng, McCrum, Christopher, Dings, Ruud P.M., Marinello, Francesco, Nilsson, Henrik, Nixon, Brett, Voskarides, Konstantinos, Yang, Long, Costa, Vincent D., Bengtsson-Palme, Johan, Bradshaw, William, Grimm, Dominik G., Kumar, Nitin, Martis, Elvis, Prieto, Daniel, Sabnis, Sandeep C., Amer, Said E.D.R., Liew, Alan W.C., Perco, Paul, Rahimi, Farid, Riva, Giuseppe, Zhang, Chongxing, Devkota, Hari P., Ogami, Koichi, Basharat, Zarrin, Fierz, Walter, Siebers, Robert, Tan, Kok H., Boehme, Karen A., Brenneisen, Peter, Brown, James A.L., Dalrymple, Brian P., Harvey, David J., Ng, Grace, Werten, Sebastiaan, Bleackley, Mark, Dai, Zhanwu, Dhariwal, Raman, Gelfer, Yael, Hartmann, Marcus D., Miotla, Pawel, Tamaian, Radu, Govender, Pragashnie, Gurney-Champion, Oliver J., Kauppila, Joonas H., Zhang, Xiaolei, Echeverría, Natalia, Subhash, Santhilal, Sallmon, Hannes, Tofani, Marco, Bae, Taeok, Bosch, Oliver, Cuív, Páraic O., Danchin, Antoine, Diouf, Barthelemy, Eerola, Tuomas, Evangelou, Evangelos, Filipp, Fabian, Klump, Hannes, Kurgan, Lukasz, Smith, Simon S., Terrier, Olivier, Tuttle, Neil, Ascher, David B., Janga, Sarath C., Schulte, Leon N., Becker, Daniel, Browngardt, Christopher, Bush, Stephen J., Gaullier, Guillaume, Ide, Kazuki, Meseko, Clement, Werner, Gijsbert D.A., Zaucha, Jan, Al-Farha, Abd A., Greenwald, Noah F., Popoola, Segun I., Rahman, Shaifur, Xu, Jialin, Yang, Sunny Y., Hiroi, Noboru, Alper, Ozgul M., Baker, Chris I., Bitzer, Michael, Chacko, George, Debrabant, Birgit, Dixon, Ray, Forano, Evelyne, Gilliham, Matthew, Kelly, Sarah, Klempnauer, Karl-Heinz, Lidbury, Brett A., Lin, Michael Z., Lynch, Iseult, Ma, Wujun, Maibach, Edward W., Mather, Diane E., Nandakumar, Kutty S., Ohgami, Robert S., Parchi, Piero, Tressoldi, Patrizio, Xue, Yu, Armitage, Charles, Barraud, Pierre, Chatzitheochari, Stella, Coelho, Luis P., Diao, Jiajie, Doxey, Andrew C., Gobet, Angélique, Hu, Pingzhao, Kaiser, Stefan, Mitchell, Kate M., Salama, Mohamed F., Shabalin, Ivan G., Song, Haijun, Stevanovic, Dejan, Yadollahpour, Ali, Zeng, Erliang, Zinke, Katharina, Alimba, C.G., Beyene, Tariku J., Cao, Zehong, Chan, Sherwin S., Gatchell, Michael, Kleppe, Andreas, Piotrowski, Marcin, Torga, Gonzalo, Woldesemayat, Adugna A., Cosacak, Mehmet I., Haston, Scott, Ross, Stephanie A., Williams, Richard, Wong, Alvin, Abramowitz, Matthew K., Effiong, Andem, Lee, Senhong, Abid, Muhammad B., Agarabi, Cyrus, Alaux, Cedric, Albrecht, Dirk R., Atkins, Gerald J., Beck, Charles R., Bonvin, A.M.J.J., Bourke, Emer, Brand, Thomas, Braun, Ralf J., Bull, James A., Cardoso, Pedro, Carter, Dee, Delahay, Robin M., Ducommun, Bernard, Duijf, Pascal H.G., Epp, Trevor, Eskelinen, Eeva-Liisa, Fallah, Mazyar, Farber, Debora B., Fernandez-Triana, Jose, Feyerabend, Frank, Florio, Tullio, Friebe, Michael, Furuta, Saori, Gabrielsen, Mads, Gruber, Jens, Grybos, Malgorzata, Han, Qian, Heinrich, Michael, Helanterä, Heikki, Huber, Michael, Jeltsch, Albert, Jiang, Fan, Josse, Claire, Jurman, Giuseppe, Kamiya, Haruyuki, de Keersmaecker, Kim, Kristiansson, Erik, de Leeuw, Frank-Erik, Li, Jiuyong, Liang, Shide, Lopez-Escamez, Jose A., Lopez-Ruiz, Francisco J., Marchbank, Kevin J., Marschalek, Rolf, Martín, Carmen S., Miele, Adriana E., Montagutelli, Xavier, Morcillo, Esteban, Nicoletti, Rosario, Niehof, Monika, O'Toole, Ronan, 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Rogerio M., An, Qianli, Andersen, Stig U., Aplin, John D., Argyropoulos, Christos, Asmann, Yan W., Assaeed, Abdulaziz M., Atanasov, Atanas G., Atchison, David A., Avery, Simon V., Avillach, Paul, Baade, Peter D., Backman, Lars, Badie, Christophe, Baldi, Alfonso, Ball, Elizabeth, Bardot, Olivier, Barnett, Adrian G., Basner, Mathias, Batra, Jyotsna, Bazanova, O.M., Beale, Andrew, Beddoe, Travis, Bell, Melanie L., Berezikov, Eugene, Berners-Price, Sue, Bernhardt, Peter, Berry, Edward, Bessa, Theolis B., Billington, Craig, Birch, John, Blakely, Randy D., Blaskovich, Mark A.T., Blum, Robert, Boelaert, Marleen, Bogdanos, Dimitrios, Bosch, Carles, Bourgoin, Thierry, Bouvard, Daniel, Boykin, Laura M., Bradley, Graeme, Braun, Daniel, Brownlie, Jeremy, Brühl, Albert, Burt, Austin, Butler, Lisa M., Byrareddy, Siddappa N., Byrne, Hugh J., Cabantous, Stephanie, Calatayud, Sara, Candal, Eva, Carlson, Kimberly, Casillas, Sònia, Castelvetro, Valter, Caswell, Patrick T., Cavalli, Giacomo, Cerovsky, 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Faville, Marty J., Fejzo, Marlena S., Festa, Fernanda, Feteira, Antonio, Flood-Page, Patrick, Forsayeth, John, Fox, Simon A., Franks, Steven J., Frentiu, Francesca D., Frilander, Mikko J., Fu, Xinmiao, Fujita, Satoshi, Galea, Ian, Galluzzi, Luca, Gani, Federica, Ganpule, Arvind P., García-Alix, Antonio, Gedye, Kristene, Giordano, Maurizio, Giunta, Cecilia, Gleeson, Paul A., Goarant, Cyrille, Gong, Haipeng, Gora, Diop, Gough, Michael J., Goyal, Ravinder, Graham, Kathryn E., Grande-Pérez, Ana, Graves, Patricia M., Greidanus, Harm, Grice, Darren, Grunau, Christoph, Gumulya, Yosephine, Guo, Yabin, Gurevich, Vsevolod V., Gusev, Oleg, Hacker, Elke, Hage, Steffen R., Hagen, Guy, Hahn, Steven, Haller, Dagmar M., Hammerschmidt, Sven, Han, Jianwei, Han, Renzhi, Handfield, Martin, Hapuarachchi, Hapuarachchige C., Harder, Timm, Hardingham, Jennifer E., Heck, Michelle, Heers, Marcel, Hew, Khe F., Higuchi, Yohei, Hilaire, Cynthia St., Hilton, Rachel, Hodzic, Enisa, Hone, Andrew, Hongoh, Yuichi, Hu, Guoku, Huber, Heinz P., Hueso, Luis E., Huirne, Judith, Hurt, Lisa, Idborg, Helena, Ikeo, Kazuho, Ingley, Evan, Jakeman, Philip M., Jensen, Arne, Jia, Hong, Jia, Husen, Jia, Shuqin, Jiang, Jianping, Jiang, Xingyu, Jin, Yi, Jo, Daehyun, Johnson, Andrew M., Johnston, Marie, Jonscher, Karen R., Jorens, Philippe G., Jorgensen, Jens O.L., Joubert, Johan W., Jung, Sin-Ho, Junior, Antonio M., Kahan, Thomas, Kamboj, Sunjeev K., Kang, Yong-Kook, Karamanos, Yannis, Karp, Natasha A., Kelly, Ryan, Kenna, Ralph, Kennedy, Jonathan, Kersten, Birgit, Khalaf, Roy A., Khalid, Javaria M., Khatlani, T., Khider, Tarig, Kijanka, Gregor S., King, Sarah R.B., Kluz, Tomasz, Knox, Paul, Kobayashi, Tatsuya, Koch, Karl-Wilhelm, Kohonen-Corish, Maija R.J., Kong, Xiangpeng, Konkle-Parker, Deborah, Korpela, Kalevi M., Kostrikis, Leondios G., Kraiczy, Peter, Kratz, Harald, Krause, Günter, Krebsbach, Paul H., Kristensen, Søren R., Kumari, Prerna, Kunimatsu, Akira, Kurdak, Hatice, Kwon, Young D., Lachat, Carl, Lagisz, 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Prince, Martin, Quinn, Gwendolyn P., Quinn, Terence J., Ramula, Satu, Rappsilber, Juri, Rehfeldt, Florian, Reiling, Jan H., Remacle, Claire, Rezaei, Mohsen, Riddick, Eric W., Ritter, Uwe, Roach, Neil W., Roberts, David D., Robles, Guillermo, Rodrigues, Tiago, Rodriguez, Cesar, Roislien, Jo, Roobol, Monique J., Rowe, Alexandra, Ruepp, Andreas, van Ruitenbeek, Jan, Rust, Petra, Saad, Sonia, Sack, George H., Santos, Manuela, Saudemont, Aurore, Sava, Gianni, Schrading, Simone, Schramm, Alexander, Schreiber, Martin, Schuler, Sidney, Schymkowitz, Joost, Sczyrba, Alexander, Seib, Kate L., Shi, Han-Ping, Shimada, Tomohiro, Shin, Jeon-Soo, Shortt, Colette, Silveyra, Patricia, Skinner, Debra, Small, Ian, Smeets, Paul A.M., So, Po-Wah, Solano, Francisco, Sonenshine, Daniel E., Song, Jiangning, Southall, Tony, Speakman, John R., Srinivasan, Mandyam V., Stabile, Laura P., Stasiak, Andrzej, Steadman, Kathryn J., Stein, Nils, Stephens, Andrew W., Stewart, Douglas I., Stine, Keith, Storlazzi, Curt, 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Michael J., Soares, António, Song, Chunjiao, Srivastava, Kshitij, Srivastava, Rupesh K., Sun, Jim, Szabo, Attila, Szymanski, Wiktor, Tai, Chan N.P., Takeuchi, Hisashi, Tanadini-Lang, S., Tang, Fei, Tao, Wanyin, Theron, G., Tian, Chang F., Tian, Yu-Shi, Tuttle, Lisa M., Valenti, Anna, Verlot, Pierre, Walker, Mirella, Wang, Jun, Welter, Danielle, Winslade, Matthew, Wu, Dalei, Wu, Yi-Rui, Xiao, Han, Xu, Beisi, Xu, Juan, Xu, Ziyue, Yang, Dongdong, Yang, Mingjun, Yankilevich, Patricio, You, Yuyi, Yu, Chenglong, Zhan, Jian, Zhang, Gong, Zhang, Kai, Zhang, Tuo, Zhang, Yi, Zhao, Guoyan, Zhao, Jing, Zhou, Xiaofan, Zhu, Zhenxing, Ajani, Penelope A., Anazodo, Udunna C., Bagloee, Saeed A., Bail, Kasia, Bar, Ido, Bathelt, Joe, Benkeser, David, Bernier, Meghan L., Blanchard, Adam M., Boakye, Dominic W., Bonatsos, Vasileios, Boon, Michele H., Bouboulis, George, Bromfield, Elizabeth, Brown, Joshua, Bul, Kim C.M., Burton, Kathryn J., Butkowski, Eugene G., Carroll, Grace, Chao, Fengqing, Charrier, 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Andreia, Lercher, Lukas, Li, Ying, Lim, Renly, Lima, Luiz R.A., Lin, Li, Ling, Tong, Liu, Yuchen, Liu, Zhonghua, Lu, Yao, Lum, Fok M., Luo, Hang, Machhi, Jatin, Macleod, Angus, Macwan, Isaac, Madala, Hanumantha R., Madani, Nima, de Maio, Nicola, Makowiecki, Kalina, Mallinson, Daniel J., Margelyte, Ruta, Maria, Caracausi, Markonis, Y., Marsili, Luca, Mavoa, Suzanne, McWilliams, Lorna, Megersa, Moa, Souto-Maior, Caetano, Menichetti, Julia, Mercieca-Bebber, Rebecca, Miller, Jack J., Minde, David-Paul M., Minges, Alexander, Mishra, Eleanor, Mishra, Virendra R., Moores, Carly, Morrice, Nicola, Moskalensky, Alexander E., Navarin, Nicolò, Negera, Edessa, Nolet, Philippe, Nordberg, Ana, Nordén, Rickard, Nowicki, Jessica P., Olova, Nelly, Olszewski, Pawel, Onzima, Robert, Pan, Chih-Long, Park, Charny, Park, Dong I., Park, Seyoung, Patil, Chandrashekhar D., Pedro, Sansoa A., Perry, Samuel R., Peter, Jessica, Peterson, Brent M., Pezzuolo, Andrea, Pozdnyakov, Ilya, Qian, Siyu, Qin, Lei, Rafe, Ali, 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Xu, Shilin, Yao, Ruifeng, Yao, Wen, Yin, Qinan, Yu, Yongbo, Zaitsu, Masayoshi, Zeineb, Zian, Zhan, Xiao-Yong, Zhang, Jilei, Zhang, Rongqiang, Zhang, Wei, Zhang, Xianglilan, Zheng, Shan, Zhou, Bailing, Zhou, Xiaoyan, Ahmad, Haroon, Akinwumi, Sayo A., Albery, Gregory F., Alhowimel, Ahmed, Ali, Junaid, Alshehri, Mansour, Alsuhaibani, Mohammed, Anikin, Andrey, Azubuike, Samuel O., Bach-Mortensen, Anders, Baltiansky, Lior, Bartas, Martin, Belachew, Kiflemariam Y., Bhardwaj, Vivek, Binder, Karin, Bland, Nicholas S., Boah, Michael, Bullen, Benjamin, Calabrò, Giovanna E., Callahan, Tiffany J., Cao, Bing, Chalmers, Kelsey, Chang, Wei, Che, Zhengping, Chen, Andrew T.Y., Chen, Haimin, Chen, Huaming, Chen, Youning, Chen, Zhao, Choi, Youngrok, Chowdhury, Mohiuddin A.K., Christensen, Martin R., Cooke, Robert S.C., Cottini, Marzia, Covington, Natalie V., Cunningham, Catriona, Delarocque, Julien, Devos, Lucie, Dhar, Aurup R., Ding, Ke-Feng, Dong, Kexian, Dong, Zheng, Dreyer, Niklas, Ekstrand, Chelsea, Fardet, Tanguy, Feleke, Berhanu E., Feurer, Thomas, Freitas, Angela, Gao, Tian, Gebremedhin, Giganti, Francesco, Grabowski, Piotr, Guerra-Mora, José R., Guo, Chengying, Guo, Xinyi, Gupta, Himanshu, He, Shuonan, Heijne, Marloes, Heinemann, Stephanie, Hogrebe, Alexander, Huang, Zhengping, Iskander-Rizk, Sophinese, Iyer, Lavanya M., Jahan, Yasmin, James, Ameh S., Joel, Emmanuel, Joffroy, Bastian, Jégousse, Clara, Kambondo, George, Karnati, Priyanka, Kaya, Cihan, Ke, An, Kelly, Daniel, Kickert, Rob, Kidibule, Peter E., Kieselmann, Jennifer P., Kim, Hyeon J., Kitazawa, Takeshi, Lamberts, Aniek, Li, You, Liang, Huakang, Linn, Sabrina N., Litfin, Thomas, Liusuo, Wang, Lygirou, Vasiliki, Mahato, Ajay K., Mai, Zhi-Ming, Major, Rupert W., Mali, Samira, Mallis, Panagiotis, Mao, Wenzhi, Marvin-Dowle, Katie, Mason, Leanda D., Merideth, Ben, Merino-Plaza, Maria J., Merlaen, Britt, Messina, Rossella, Mishra, Anand K., Muhammad, Junaid, Musinguzi, Conrad, Nanou, Afroditi, Naqash, Amreen, Nguyen, Joe T., Nguyen, Thi T.H., Ni, Duan, Nida, Notcovich, Shirli, Ohst, Barnabas, Ollivier, Quinn R., Osses, Daniël F., Peng, Xiangda, Plantinga, Arnoud, Pulia, Michael, Rafiq, Muhammad, Raman, Ayush, Raucher-Chéné, Rawski, Rafal, Ray, Asit, Razak, Lubna A., Rudolf, Kevin, Rusch, Peter, Sadoine, Margaux L., Schmidt, Axel, Schurr, Roey, Searles, Stephen, Sharma, Saurab, Sheehan, Barry, Shi, Chunhu, Shohayeb, Belal, Sommerlad, Andrew, Strehlow, Jan, Sun, Xianbao, Sundar, Raghav, Taherzadeh, Ghazaleh, Tahir, Nur D.M., Tang, Jun, Testa, Jean, Tian, Zhiqi, Tingting, Qian, Verheijen, Geert P., Vickstrom, Casey, Wang, Teng, Wang, Xiaomin, Wang, Zhenxing, Wei, Pan, Wilson, Alex, Wyart, Yassine, Abdul-Amir, Yousefzadeh, Abbas, Zare, Asma, Zeng, Zhen, Zhang, Chengrong, Zhang, Haowen, Zhang, Linxing, Zhang, Tongchuan, Zhang, Weijia, Zhang, Zhe, Zhou, Jianyu, Zhu, Dongjie, Adamo, Vincenzo, Adeyemo, Adebolajo A., Aggelidou, Maria, Al-Owaifeer, Adi M., Al-Riyami, Arwa Z., Alzghari, Saeed K., Andersen, 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Hunter, Kylie E., Ijzerman, Adriaan P., Jesus, Carlos, Jian, Gao, Lewis, James S., Kanj, Souha S., Kaur, Harsheen, Kelly, Shona, Kheir, Fayez, Kichatova, V.S., Kiyani, Musa, Klein, Reinhild, Kovesi, Tom, Kraschnewski, Jennifer L., Kumar, Addanki P., Labutin, Dmitry, Lazo-Langner, Alejandro, Leclercq, Guy, Li, Maoteng, Li, Qingchun, Li, Tangliang, Li, Yongzhe, Liao, Wei-Ting, Liao, Zheng-Yin, Lin, Jessica, Lizer, J., Lobreglio, Giambattista, Lowies, Cher, Lu, Cheng, Majeed, Haroon, Martin, Adam, Martinez-Sobrido, Luis, Meresh, Edwin, Middelveen, Marianne, Mohebbi, Alireza, Mota, Jorge, Mozaheb, Zahra, Muyaya, Ley, Nandhakumar, Amar, Ng, Sheryl H.X., Obeidat, Monther, Oh, Deog-Hwan, Owais, Mohammed, Pace-Asciak, Pia, Panwar, Ajay, Park, Caroline, Patterson, Chris, Penagos-Tabaree, Felipe, Pianosi, Paolo T., Pinzi, Valentina, Pridans, Clare, Psaroulaki, Anna, Pujala, Ravi K., Pulido-Arjona, Leonardo, Qi, Peng-Fei, Rahman, Proton, Rai, Nayanjot K., Rassaf, Tienush, Refardt, Julie, Ricciardi, Walter, Riess, Olaf, Rovas, Alexandros, Sacks, Frank M., Saleh, Sherif, Sampson, Christopher, Schmutz, Axel, Sepanski, Robert, Sharma, Neeraj, Singh, Manisha, Spearman, Paul, Subramaniapillai, Mehala, Swali, Ritu, Tan, Cher M., Tellechea, Juan I., Thomas, Lisa-Marie, Tong, Xin, Vavvas, Demetrios G., Veys, Ralf, Vitriol, Veronica, Wang, Horng-Dar, Wang, Jinhui, Wang, Jiucun, Waugh, Jason, Webb, S.A., Williams, Brendan A., Workman, Alan D., Xiang, Tingxiu, Xie, Li-Xin, Xu, Jun, Xu, Taosheng, Yang, Chongjun, Yoon, Jihoon G., Yuan, Christina M., Zaritsky, Arno, Zhang, Yao, Zhao, Haochen, Zuckerman, Hannah, Lyu, Ran, and Pullan, Wayne
- Abstract
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations. More importantly, annotations of the same document pairs contributed by different scientists were highly concordant. We further show that the three representative baseline methods used to generate recommended articles for evaluation (Okapi Best Matching 25, Term Frequency-Inverse Document Frequency and PubMed Related Articles) had similar overall performances. Additionally, we found that these methods each tend to produce distinct collections of recommended articles, suggesting that a hybrid method may be required to completely capture all relevant articles. The established database server located at https://relishdb.ict.griffith.edu.au is freely available for the downloading of annotation data and the blind testing of new methods. We expect that this benchmark will be useful for stimulating the development of new powerful techniques for title and title/abstract-based search engines for relevant articles in biomedical science.
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- 2019
240. The contribution of acute infarcts to cerebral small vessel disease progression
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Ter Telgte, Annemieke, Wiegertjes, Kim, Gesierich, Benno, Marques, José P, Huebner, Mathias, de Klerk, Jabke J, Schreuder, Floris H B M, Araque Caballero, Miguel A, Kuijf, Hugo J, Norris, David G, Klijn, Catharina J M, Dichgans, Martin, Tuladhar, Anil M, Duering, Marco, de Leeuw, Frank-Erik, Ter Telgte, Annemieke, Wiegertjes, Kim, Gesierich, Benno, Marques, José P, Huebner, Mathias, de Klerk, Jabke J, Schreuder, Floris H B M, Araque Caballero, Miguel A, Kuijf, Hugo J, Norris, David G, Klijn, Catharina J M, Dichgans, Martin, Tuladhar, Anil M, Duering, Marco, and de Leeuw, Frank-Erik
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- 2019
241. Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration
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Smith, Eric E, Biessels, Geert Jan, De Guio, François, de Leeuw, Frank Erik, Duchesne, Simon, Düring, Marco, Frayne, Richard, Ikram, M Arfan, Jouvent, Eric, MacIntosh, Bradley J, Thrippleton, Michael J, Vernooij, Meike W, Adams, Hieab, Backes, Walter H, Ballerini, Lucia, Black, Sandra E, Chen, Christopher, Corriveau, Rod, DeCarli, Charles, Greenberg, Steven M, Gurol, M Edip, Ingrisch, Michael, Job, Dominic, Lam, Bonnie Y K, Launer, Lenore J, Linn, Jennifer, McCreary, Cheryl R, Mok, Vincent C T, Pantoni, Leonardo, Pike, G Bruce, Ramirez, Joel, Reijmer, Yael D, Romero, Jose Rafael, Ropele, Stefan, Rost, Natalia S, Sachdev, Perminder S, Scott, Christopher J M, Seshadri, Sudha, Sharma, Mukul, Sourbron, Steven, Steketee, Rebecca M E, Swartz, Richard H, van Oostenbrugge, Robert, van Osch, Matthias, van Rooden, Sanneke, Viswanathan, Anand, Werring, David, Dichgans, Martin, Wardlaw, Joanna M, Smith, Eric E, Biessels, Geert Jan, De Guio, François, de Leeuw, Frank Erik, Duchesne, Simon, Düring, Marco, Frayne, Richard, Ikram, M Arfan, Jouvent, Eric, MacIntosh, Bradley J, Thrippleton, Michael J, Vernooij, Meike W, Adams, Hieab, Backes, Walter H, Ballerini, Lucia, Black, Sandra E, Chen, Christopher, Corriveau, Rod, DeCarli, Charles, Greenberg, Steven M, Gurol, M Edip, Ingrisch, Michael, Job, Dominic, Lam, Bonnie Y K, Launer, Lenore J, Linn, Jennifer, McCreary, Cheryl R, Mok, Vincent C T, Pantoni, Leonardo, Pike, G Bruce, Ramirez, Joel, Reijmer, Yael D, Romero, Jose Rafael, Ropele, Stefan, Rost, Natalia S, Sachdev, Perminder S, Scott, Christopher J M, Seshadri, Sudha, Sharma, Mukul, Sourbron, Steven, Steketee, Rebecca M E, Swartz, Richard H, van Oostenbrugge, Robert, van Osch, Matthias, van Rooden, Sanneke, Viswanathan, Anand, Werring, David, Dichgans, Martin, and Wardlaw, Joanna M
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- 2019
242. The contribution of acute infarcts to cerebral small vessel disease progression
- Author
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Beeldverwerking ISI, Brain, Ter Telgte, Annemieke, Wiegertjes, Kim, Gesierich, Benno, Marques, José P, Huebner, Mathias, de Klerk, Jabke J, Schreuder, Floris H B M, Araque Caballero, Miguel A, Kuijf, Hugo J, Norris, David G, Klijn, Catharina J M, Dichgans, Martin, Tuladhar, Anil M, Duering, Marco, de Leeuw, Frank-Erik, Beeldverwerking ISI, Brain, Ter Telgte, Annemieke, Wiegertjes, Kim, Gesierich, Benno, Marques, José P, Huebner, Mathias, de Klerk, Jabke J, Schreuder, Floris H B M, Araque Caballero, Miguel A, Kuijf, Hugo J, Norris, David G, Klijn, Catharina J M, Dichgans, Martin, Tuladhar, Anil M, Duering, Marco, and de Leeuw, Frank-Erik
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- 2019
243. Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration
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ZL Algemene Neurologie Medisch, Brain, Circulatory Health, Smith, Eric E, Biessels, Geert Jan, De Guio, François, de Leeuw, Frank Erik, Duchesne, Simon, Düring, Marco, Frayne, Richard, Ikram, M Arfan, Jouvent, Eric, MacIntosh, Bradley J, Thrippleton, Michael J, Vernooij, Meike W, Adams, Hieab, Backes, Walter H, Ballerini, Lucia, Black, Sandra E, Chen, Christopher, Corriveau, Rod, DeCarli, Charles, Greenberg, Steven M, Gurol, M Edip, Ingrisch, Michael, Job, Dominic, Lam, Bonnie Y K, Launer, Lenore J, Linn, Jennifer, McCreary, Cheryl R, Mok, Vincent C T, Pantoni, Leonardo, Pike, G Bruce, Ramirez, Joel, Reijmer, Yael D, Romero, Jose Rafael, Ropele, Stefan, Rost, Natalia S, Sachdev, Perminder S, Scott, Christopher J M, Seshadri, Sudha, Sharma, Mukul, Sourbron, Steven, Steketee, Rebecca M E, Swartz, Richard H, van Oostenbrugge, Robert, van Osch, Matthias, van Rooden, Sanneke, Viswanathan, Anand, Werring, David, Dichgans, Martin, Wardlaw, Joanna M, ZL Algemene Neurologie Medisch, Brain, Circulatory Health, Smith, Eric E, Biessels, Geert Jan, De Guio, François, de Leeuw, Frank Erik, Duchesne, Simon, Düring, Marco, Frayne, Richard, Ikram, M Arfan, Jouvent, Eric, MacIntosh, Bradley J, Thrippleton, Michael J, Vernooij, Meike W, Adams, Hieab, Backes, Walter H, Ballerini, Lucia, Black, Sandra E, Chen, Christopher, Corriveau, Rod, DeCarli, Charles, Greenberg, Steven M, Gurol, M Edip, Ingrisch, Michael, Job, Dominic, Lam, Bonnie Y K, Launer, Lenore J, Linn, Jennifer, McCreary, Cheryl R, Mok, Vincent C T, Pantoni, Leonardo, Pike, G Bruce, Ramirez, Joel, Reijmer, Yael D, Romero, Jose Rafael, Ropele, Stefan, Rost, Natalia S, Sachdev, Perminder S, Scott, Christopher J M, Seshadri, Sudha, Sharma, Mukul, Sourbron, Steven, Steketee, Rebecca M E, Swartz, Richard H, van Oostenbrugge, Robert, van Osch, Matthias, van Rooden, Sanneke, Viswanathan, Anand, Werring, David, Dichgans, Martin, and Wardlaw, Joanna M
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- 2019
244. Adiposity is related to cerebrovascular and brain volumetry outcomes in the RUN DMC study
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Arnoldussen, Ilse A. C., Gustafson, Deborah R., Leijsen, Esther M. C., de Leeuw, Frank-Erik, Kiliaan, Amanda J., Arnoldussen, Ilse A. C., Gustafson, Deborah R., Leijsen, Esther M. C., de Leeuw, Frank-Erik, and Kiliaan, Amanda J.
- Abstract
OBJECTIVE: Adiposity predictors, body mass index (BMI), waist circumference (WC), and blood leptin and total adiponectin levels were associated with components of cerebral small vessel disease (CSVD) and brain volumetry in 503 adults with CSVD who were ≥50 years of age and enrolled in the Radboud University Nijmegen Diffusion Tensor and Magnetic Resonance Imaging Cohort (RUN DMC). METHODS: RUN DMC participants were followed up for 9 years (2006-2015). BMI, WC, brain imaging, and dementia diagnoses were evaluated at baseline and follow-up. Adipokines were measured at baseline. Brain imaging outcomes included CSVD components, white matter hyperintensities, lacunes, microbleeds, gray and white matter, hippocampal, total brain, and intracranial volumes. RESULTS: Cross-sectionally among men at baseline, higher BMI, WC, and leptin were associated with lower gray matter and total brain volumes, and higher BMI and WC were associated with lower hippocampal volume. At follow-up 9 years later, higher BMI was cross-sectionally associated with lower gray matter volume, and an obese WC (>102 cm) was protective for ≥1 lacune or ≥1 microbleed in men. In women, increasing BMI and overweight or obesity (BMI ≥25 kg/m2 or WC >88 cm) were associated with ≥1 lacune. Longitudinally, over 9 years, a baseline obese WC was associated with decreasing hippocampal volume, particularly in men, and increasing white matter hyperintensity volume in women and men. CONCLUSIONS: Anthropometric and metabolic adiposity predictors were differentially associated with CSVD components and brain volumetry outcomes by sex. Higher adiposity is associated with a vascular-neurodegenerative spectrum among adults at risk for vascular forms of cognitive impairment and dementias.
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- 2019
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245. Stroke incidence in young adults according to age, subtype, sex, and time trends
- Author
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Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Opleiding Neurologie, ZL Cerebrovasculaire Ziekten Medisch, Brain, Ekker, Merel S., Verhoeven, Jamie I., Vaartjes, Ilonca, van Nieuwenhuizen, Koen M., Klijn, Catharina J.M., de Leeuw, Frank Erik, Cardiovasculaire Epi Team 5, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Opleiding Neurologie, ZL Cerebrovasculaire Ziekten Medisch, Brain, Ekker, Merel S., Verhoeven, Jamie I., Vaartjes, Ilonca, van Nieuwenhuizen, Koen M., Klijn, Catharina J.M., and de Leeuw, Frank Erik
- Published
- 2019
246. The neural underpinnings of facial emotion recognition in ischemic stroke patients.
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van den Berg, Nils S., de Haan, Edward H. F., Huitema, Rients B., Spikman, Jacoba M., de Leeuw, Frank Erik, Luijckx, Gert Jan, Raemaekers, Matthijs A.H.L.L., Smits, Anouk R, Schmand, Ben A, Scholte, H Steven, Spikman, Jacoba M, Kappelle, L Jaap, Geerligs, Linda, van Zandvoort, Martine J.E., Caan, Matthan W.A., Prokop, Mathias, Ramsey, Nick F, Lammers, Nikki A, Seijdel, Noor, and Nederkoorn, Paul J
- Subjects
EMOTION recognition ,ISCHEMIC stroke ,PREFRONTAL cortex ,STROKE patients ,EMOTIONS ,FACIAL expression & emotions (Psychology) - Abstract
Deficits in facial emotion recognition occur frequently after stroke, with adverse social and behavioural consequences. The aim of this study was to investigate the neural underpinnings of the recognition of emotional expressions, in particular of the distinct basic emotions (anger, disgust, fear, happiness, sadness and surprise). A group of 110 ischaemic stroke patients with lesions in (sub)cortical areas of the cerebrum was included. Emotion recognition was assessed with the Ekman 60 Faces Test of the FEEST. Patient data were compared to data of 162 matched healthy controls (HC's). For the patients, whole brain voxel‐based lesion–symptom mapping (VLSM) on 3‐Tesla MRI images was performed. Results showed that patients performed significantly worse than HC's on both overall recognition of emotions, and specifically of disgust, fear, sadness and surprise. VLSM showed significant lesion–symptom associations for FEEST total in the right fronto‐temporal region. Additionally, VLSM for the distinct emotions showed, apart from overlapping brain regions (insula, putamen and Rolandic operculum), also regions related to specific emotions. These were: middle and superior temporal gyrus (anger); caudate nucleus (disgust); superior corona radiate white matter tract, superior longitudinal fasciculus and middle frontal gyrus (happiness) and inferior frontal gyrus (sadness). Our findings help in understanding how lesions in specific brain regions can selectively affect the recognition of the basic emotions. [ABSTRACT FROM AUTHOR]
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- 2021
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247. Interaction Between Hypertension, apoE, and Cerebral White Matter Lesions
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de Leeuw, Frank-Erik, Richard, Florence, de Groot, Jan Cees, van Duijn, Cornelia M., Hofman, Albert, van Gijn, Jan, and Breteler, Monique M.B.
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- 2004
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248. Operational Definitions for the NINDS-AIREN Criteria for Vascular Dementia: An Interobserver Study
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van Straaten, Elisabeth C.W., Scheltens, Philip, Knol, Dirk L., van Buchem, Mark A., van Dijk, Ewout J., Hofman, Paul A.M., Karas, Giorgos, Kjartansson, Olafur, de Leeuw, Frank-Erik, Prins, Niels D., Schmidt, Reinhold, Visser, Marieke C., Weinstein, Henry C., and Barkhof, Frederik
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- 2003
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249. Serum Carotenoids and Cerebral White Matter Lesions: The Rotterdam Scan Study
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den Heijer, Tom, Launer, Lenore J., de Groot, Jan Cees, de Leeuw, Frank-Erik, Oudkerk, Matthijs, van Gijn, Jan, Hofman, Albert, and Breteler, Monique M. B.
- Published
- 2001
250. Association between blood pressure levels over time and brain atrophy in the elderly
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Heijer, Tom den, Skoog, Ingmar, Oudkerk, Matthijs, de Leeuw, Frank-Erik, de Groot, Jan Cees, Hofman, Albert, and Breteler, Monique M.B
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- 2003
- Full Text
- View/download PDF
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