201. Therapeutic value of citicoline in the treatment of glaucoma (computerized and automated perimetric investigation).
- Author
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Pecori Giraldi J, Virno M, Covelli G, Grechi G, and De Gregorio F
- Subjects
- Adult, Aged, Humans, Middle Aged, Scotoma complications, Time Factors, Visual Field Tests, Choline analogs & derivatives, Cytidine Diphosphate Choline pharmacology, Glaucoma, Open-Angle drug therapy, Visual Fields drug effects
- Abstract
The favourable neurotrophic effects obtained by means of the intramuscular administration of citicoline, one of the intermediate compounds of phospholipids, on the visual field of patients suffering from open-angle glaucoma are referred. The drug was administered at the dose of 1 gm for ten consecutive days. Visual field was examined by means of central computerized perimetry and automated perimetry. All patients had well controlled intraocular pressure through beta-blockers, but presented characteristic glaucomatous perimetric defects. It is suggested that citicoline might be administered as a useful complement to conventional hypotensive therapy, since it acts positively on the glaucomatous optic nerve damage.
- Published
- 1989
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