201. Choice Reaction Time and Adequacy of Dialysis: A New Application of an Old Method.
- Author
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Ahmad, Suhail
- Subjects
- *
DIALYSIS (Chemistry) , *FILTERS & filtration , *HEMODIALYSIS , *KIDNEY diseases , *PARKINSON'S disease - Abstract
Background: Choice Reaction Time (CRT) is the time it takes for a subject to accurately respond to a flashing panel of lights. The CRT has been used to assess the quality of dialysis in hemodialysis patients and to assess the neurological impairments in patients with Parkinson's disease. Methods: Three groups of end-stage renal disease (ESRD) patients on three different renal replacement therapies were tested using CRT: intermittent peritoneal dialysis (IPD, n = 11), thrice weekly hemodialysis (HD, n = 22), and well-functioning kidney transplant (Tx, n = 6). A group of volunteers with normal renal function (NL, n = 12) was also tested. Results: The CRT was significantly longer in IPD patients (618 ± 89 ms) than observed in the other three groups (p < 0.0001). CRT in HD patients was 461 ± 50 ms, which was significantly longer than in Tx patients (396 ± 25 ms, p = 0.05). However, the CRT in the Tx patients was no different from the NL (382 ± 22, p = 0.32). There was a strong negative correlation between CRT and weekly creatinine clearance in the IPD group (r =- .96) and between the dialysis index and CRT in HD (r =- 0.79). Conclusions: CRT may be a useful tool in assessing the adequacy of dialysis. [ABSTRACT FROM AUTHOR]
- Published
- 2003
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