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Optimizing the delivery and penetration of nano-sized drugs within liver cancer sites, along with remodeling the tumor microenvironment, is crucial for enhancing the efficacy of chemotherapeutic agents. For this study, a platelet (PLT)-mediated nanodrug delivery system (DASA+ATO@PLT) was developed to improve the effectiveness of chemotherapy. This system delivers nano-sized dasatinib and atovaquone specifically to liver tumor sites and facilitates intra-tumoral permeation upon release. Through JC-1, immunohistochemistry, and DNA damage analyses, the therapeutic effect of DASA+ATO@PLT was assessed. In vitro simulation and intravital imaging were carried out to determine the accumulation of dasatinib and atovaquone in liver tumor sites. The experiment demonstrated the accumulation of dasatinib and atovaquone in tumor sites, followed by deep permeation in the tumor microenvironment with the assistance of PLTs, while simultaneously revealing the ability of DASA+ATO@PLT to remodel the liver cancer microenvironment (overcoming hypoxia) and enhance chemotherapeutic efficacy. This system utilizes the natural tumor recognition ability of PLTs and enhances the chemo-immunotherapeutic effect through targeted delivery of nano-chemotherapeutic drugs to the tumor, resulting in effective accumulation and infiltration. The PLT-mediated nanodrug delivery system serves as a “Trojan horse” to carry therapeutic drugs as cargo and deliver them to target cells, leading to favorable outcomes.

To explore the effect of the photoperiod on the accumulation and distribution of dry matter in potato, a pot experiment was carried out in 2021 and 2022 with two varieties (Atlantic and Hezuo 88). The varieties were used as the main plot, and light treatments (short-day and long-day) were used as the subplot. The results showed that extended hours of light delayed tuber formation in Hezuo 88, however, the effect was not obvious for the Atlantic. Comprehensive analyses were carried out using the potato developmental process, dynamic equation fitting of the tuber and whole-plant dry matter accumulation, and the dry matter accumulation and distribution rate of each organ of the two varieties under two photoperiods. The two photoperiods had different effects on the parameters of rapid tuber and whole-plant dry matter accumulation: the starting point of the period of the rapid dry matter accumulation (t1), the duration period of the rapid dry matter accumulation (Δt), and the average growth rate of the period of the rapid dry matter accumulation (Vmean). According to comprehensive analysis, tuber dry matter accumulation in Atlantic was the highest under the short-day condition, while Hezuo 88 showed the lowest tuber dry matter accumulation under the long-day condition and was the latest to enter the rapid tuber dry matter accumulation period. The whole-plant dry matter accumulation in Atlantic was the highest under the long-day condition and lowest in Hezuo 88; meanwhile, Hezuo 88 was the latest to enter the rapid whole-plant dry matter accumulation period. In terms of the dry matter accumulation and dry matter partitioning ratio of various organs, Hezuo 88 had the lowest mean tuber dry matter accumulation and partitioning ratio under the long-day condition but the highest mean stem, leaf, root, underground stem, and stolon dry matter partitioning ratio. On the contrary, Atlantic had the highest mean tuber dry matter accumulation and portioning ratio under the short-day condition but the lowest mean stem, leaf, root, underground stem, and stolon dry matter partitioning ratio. It was concluded that different varieties of potato respond differently to the photoperiod. In the case of Hezuo 88, prolonging the photoperiod affected the dynamics and distribution of dry matter accumulation; increased the stem, leaf, root, and underground stem dry matter partitioning ratio; and decreased the tuber dry matter partitioning ratio, which resulted in a decrease in tuber dry matter accumulation and consequently delayed the emergence of the equilibrium period between the aboveground and underground dry matter.

A field experiment with double cropping rice was carried out to study the foliar application effects of dicarboxylicdimethylammonium chloride (DDAC) on cadmium (Cd) and arsenic (As) accumulation in rice grains. The results showed that the spraying of DDAC could significantly reduce the accumulation of Cd and As in rice grains. The highest reductions in Cd and As content were observed when 1.5 mmol L−1 DDAC was sprayed, with 49.1% and 27.4% reductions in Cd and As content in early rice grains and 56.5% and 28.1% reductions in Cd and As content in late rice grains, respectively. In addition, the content of calcium (Ca) in rice grains increased significantly after DDAC foliar application, which was also conducive to the synthesis of amino acids such as glutamate (Glu), glycine (Gly) and cysteine (Cys) in rice grains. The results indicated that the foliar spraying of DDAC can inhibit the absorption, transport, accumulation and toxicity of Cd and As in rice grains by increasing amino acid synthesis and regulating the absorption and transport of essential elements.

Microcystins (MCs), being among the most concerned cyanobacterial toxins and with acute hepatotoxic effects, can induce liver damage and even lead to liver cancer after long-term intake. Addition to existing in contaminated water and aquatic products, MCs can also be accumulated in crops via polluted irrigation water, which could increase the health risk of human. In this paper, we systematically reviewed the enrichment characteristics of MCs in different crops and their toxicities to those crops. The potential health risks from MCs residues in edible parts of crops were also discussed.

The aim of this study was to determine the heavy metals concentrations in soil, inflorescences of Brassica napus and rapeseed honey sampled from some regions of north-eastern Bulgaria. Thirteen locations were selected for experimental studies. The soils, plants and honeys samples were taken from conventional beekeeping areas away from major industrial pollutants. The median amounts of elements in the soil samples (mg/kg DW) are 1.1246 for Fe(s), 0.7048 for Al(s), 0.5636 for Pb(s), 0.1658 for Cu(s) and 0.0148 for Zn(s). The median amounts of heavy metals measured in the inflorescences of Brassica napus (mg/ kg DW) are 5.5430 for Fe(p), 2.9095 for Zn(p), 1.3225 for Pb(p), 0.2593 for Cu(p) and 0.2105 for Al(p). The median heavy metals concentrations in tested honey (mg/kg DW) are 1.0026 for Fe(h), 0.1849 for Al(h), 0.1832 for Pb(h), 0.1250 for Zn(h), 0.0702 for. Cu(h). The relationship between the heavy metal in soil, plants and honey was investigated using the Spearman's rank correlation coefficient. Significant differences in the concentrations of Fe(s), Al(s) and Pb(s) in soils, Fe(p) and Zn(p) in the plant samples, Fe(h) in honey samples from the different locations were found. The heavy metal content tested in honey did not pose a risk to human health.

Abstract Background Nanodiamonds (NDs) have gained a rapidly growing interest in biomedical applications; however, little is known regarding their biokinetics owing to difficulties in measurements and limited synthesis/purification technologies. In this study, we investigated the distribution kinetics of detonation-synthesized NDs in mice via intravenous injection to evaluate the parameters that determine the behavior of the particles. We prepared two distinctive NDs that controlled the sp 3 /sp 2 carbon ratio and particle size by coating them with serum proteins. The four control samples were intravenously injected into mice, and tissue distribution and clearance were evaluated at 30 min and 1, 7, and 28 days post-injection. Results The sp 3 /sp 2 carbon ratio showed no correlation with the organ distribution of the NDs. However, hydrodynamic size showed an excellent correlation with organ distribution levels: a negative correlation in the liver and positive correlations in the spleen and lungs. Furthermore, the deposition levels of NDs in the lung suggest that particles smaller than 300 nm could avoid lung deposition. Finally, a similar organ distribution pattern was observed in mice injected with carbon black nanoparticles controlled hydrodynamic size. Conclusions In conclusion, the tissue distribution of NDs is modulated not by the sp 3 /sp 2 carbon ratio but by the hydrodynamic size, which can provide helpful information for targeting the tissue of NDs. Furthermore, the organ distribution pattern of the NDs may not be specific to NDs but also can apply to other nanoparticles, such as carbon black.

Although most processes governing the surface mass balance on mountain glaciers are well understood, the causes and extent of spatial variability in accumulation remain poorly constrained. In the present study, we couple an energy balance–snow and firn mass-balance model to terrain-based modelling routines estimating mass redistribution by snowdrift, preferential deposition and avalanching. We find this newly coupled model improves the spatial accuracy of winter balance simulations on Storglaciären, Sweden, while retaining versatility and a low computational cost. Accumulation on Storglaciären is primarily driven by direct precipitation, which is locally increased due to small-scale orographic effects. Wind-driven snow transport leads to substantial deposition in the accumulation zone and slight erosion in the ablation zone. Avalanching is the smallest contributor to winter balance, but cannot be neglected. The role of mass transporting processes in maintaining the current mass equilibrium on Storglaciären highlights the necessity to understand the links between climatic predictors and accumulation in order to accurately assess climate sensitivity.

Yi Zhen Tan,1 Lucy R Thomsen,1 Nensi Shrestha,1 Adalberto Camisasca,2 Silvia Giordani,2 Rhonda Rosengren1 1Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9016, New Zealand; 2School of Chemical Sciences, Dublin City University, Glasnevin, Dublin, D09 NA55, IrelandCorrespondence: Rhonda Rosengren, Department of Pharmacology and Toxicology, 18 Frederick Street, Dunedin, 9016, New Zealand, Tel +64 3 479 9141, Fax +64 3 479 9140, Email rhonda.rosengren@otago.ac.nzBackground: A nanoscale drug carrier could have a variety of therapeutic and diagnostic uses provided that the carrier is biocompatible in vivo. Carbon nano-onions (CNOs) have shown promising results as a nanocarrier for drug delivery. However, the systemic effect of CNOs in rodents is unknown. Therefore, we investigated the toxicity of CNOs following intravenous administration in female BALB/c mice.Results: Single or repeated administration of oxi-CNOs (125, 250 or 500 μg) did not affect mouse behavior or organ weight and there was also no evidence of hepatotoxicity or nephrotoxicity. Histological examination of organ slices revealed a significant dose-dependent accumulation of CNO aggregates in the spleen, liver and lungs (p< 0.05, ANOVA), with a trace amount of aggregates appearing in the kidneys. However, CNO aggregates in the liver did not affect CYP450 enzymes, as total hepatic CYP450 as well as CYP3A catalytic activity, as meased by erythromycin N-demethylation, and protein levels showed no significant changes between the treatment groups compared to vehicle control. CNOs also failed to act as competitive inhibitors of CYP3A in vitro in both mouse and human liver microsomes. Furthermore, CNOs did not cause oxidative stress, as indicated by the unchanged malondialdehyde levels and superoxide dismutase activity in liver microsomes and organ homogenates.Conclusion: This study provides the first evidence that short-term intravenous administration of oxi-CNOs is non-toxic to female mice and thus could be a promising novel and safe drug carrier.Keywords: carbon nano-onions, drug carriers, intravenous administration, toxicity, accumulation, drug metabolism, oxidative stress

Abstract. Salinity and heavy metals pollution are the root causes of many environmental problems. This study aims to determine the effect of NaCl-induced salinity and Pb(NO3)2 on chlorophyll, proline content, and lead accumulation in shoots and roots of Atriplex canesens. Sowing was carried out in plastic pots (16 cm in diameter and 13.8 cm high) containing a mixture of sand/compost. The irrigation of plants was performed with distilled water and Hoagland nutrient solution. After four months of growth, the plants were subjected to either 0.50 or 3% of NaCl combined with 800, 1600, and 2400 ppm of Pb(NO3)2 for a duration of one month, then we performed biochemical and chemical analyses on the plants. Results showed that the combined influence of strong salinity and lead caused a reduction of chlorophyll and increased proline and lead accumulation in plant tissues. Lead significantly accumulated in the roots compared to the shoots of the plants.

Indiscriminate industrialization and urbanization have negatively impacted our environment. One of the common environmental problems in semi-urban areas in India is the discharge of inefficiently treated municipal, industrial and domestic wastewater into the environment, resulting in the degradation of soil and water qualities. Depleting freshwater resources have led Indian farmers to look for easily available, cheaper, and nutrient-rich sources of irrigation water in the form of wastewater; however, this also led to increased pollutant transfer to the soils. Known as persistent pollutants, heavy metals such as cadmium (Cd), copper (Cu), chromium (Cr), lead (Pb), mercury (Hg), and a few others are potentially hazardous due to their non-biodegradable nature, extended biological half-lives, and biological interactions. These heavy metals can bind to soil surfaces and then be absorbed by plant tissues. Vegetables supply micronutrients, antioxidants, vitamins, and other nutrients essential for human growth. Therefore, the consumption of vegetables/crops grown in wastewater-irrigated land poses a potential threat to humans. Since wastewater irrigation cannot be eliminated in the Indian (semi-)urban areas because of the ever-increasing demand for irrigation water, it is important to assess the impact of wastewater irrigation. This review article congregates the findings of studies from India wherein heavy metal contaminations in vegetables have been reported. An attempt was made to estimate the risk to human health because of the long-term consumption of vegetables cultivated in wastewater-irrigated lands from the Indian sites. HIGHLIGHTS Heavy metals in vegetables produced from wastewater-irrigated croplands in India.; Common sources contribute to heavy metals in soils.; Geochemistry of heavy metals regulates the transfer factor more than plant physiology.; Risk to human health associated with heavy metals.;

The health concerns associated with heavy metal pollution (HMP) in agricultural soils have garnered attention on a global scale, and evaluations of the dangers to human health are based on research on the buildup of heavy metals in soil-plant systems. The pedosphere, hydrosphere, atmosphere, lithosphere, and biosphere all suffer from environmental pollution. As a result of the industrialization of many nations, heavy metal pollution is one of the most important environmental problems today. Heavy metal pollutants in the environment have been removed using a variety of ways, however these procedures have drawbacks such high cost, lengthy process times, logistical issues, and mechanical complexity. To use phytoremediation, which uses plants to remove, transport, and stabilize heavy metals from soil and water, one must understand the accumulation of heavy metals in plants and the function of plants in eliminating contaminants. Physiological and metabolic processes that enable plants to phytoremediator heavy metal-contaminated locations are now being optimized via genetic engineering techniques. This review investigated the accumulation of seven common heavy metals in soil agriculture systems: Cd, Cr, As, Pb, Hg, Cu, and Zn. It is reported that wheat was generally more prone than corn to acquire heavy metals. The seven heavy metals were ranked as follows, in ascending order of accumulation in grains: Pb < Cr < Zn < As < Cu < Cd < Pb < Cr < Cu < As < Hg.

Seagrass beds are susceptible to deterioration and heavy metals represent a crucial impact factor. The accumulation of heavy metal in two tropical seagrass species were studied in South China in this study and multiple methods were used to identify the heavy metal sources. E. acoroides (Enhalus acoroides) and T. hemperichii (Thalassia hemperichii) belong to the genus of Enhalus and Thalassia in the Hydrocharitaceae family, respectively. Heavy metal concentrations in the two seagrasses followed the order of Cr > Zn > Cu > Ni > As > Pb > Co > Cd based on the whole plant, and their bioconcentration factors were 31.8 ± 29.3 (Cr), 5.7 ± 1.3 (Zn), 7.0 ± 3.8 (Cu), 3.0 ± 1.9 (Ni), 1.2 ± 0.3 (As), 1.7 ± 0.9 (Pb), 9.1 ± 11.1 (Co) and 2.8 ± 0.6 (Cd), indicating the intense enrichment in Co and Cr within the two seagrasses. The two seagrasses were prone to accumulate all the listed heavy metals (except for As in E. acoroides), especially Co (BCFs of 1124) and Cr (BCFs of 2689) in the aboveground parts, and the belowground parts of both seagrasses also accumulated most metals (BCFs of 27) excluding Co and Pb. The Pb isotopic ratios (mean 208Pb/204Pb, 207Pb/204Pb and 206Pb/204Pb values of 38.2054, 15.5000 and 18.3240, respectively) and Cd isotopic compositions (δ114/110Cd values ranging from –0.09‰ to 0.58‰) within seagrasses indicated the anthropogenic sources of Pb and Cd including coal combustion, traffic emissions and agricultural activities. This study described the absorption characteristics of E. acoroides and T. hemperichii to some heavy metals, and further demonstrated the successful utilization of Pb and Cd isotopes as discerning markers to trace anthropogenic origins of heavy metals (mainly Pb and Cd) in seagrasses. Pb and Cd isotopes can mutually verify and be helpful to understand more information in pollution sources and improve the reliability of conclusion deduced from concentrations or a single isotope.

The sediments of rivers or harbours have always been considered sinks for numerous heavy metals, pesticides, chemicals and contaminants of anthropogenic origin. The eco-friendly management of contaminated sediment have received attention due to their large-scale presence in harbour areas. Application of bioenergy crop species, such as Salix spp., have shown a strong potential for reducing heavy metals from the contaminated sediment. The aim of this study was to investigate the application of Salix spp. on contaminated dredged sediment and heavy metal accumulation and translocation patterns in different parts of plants. Two Salix cultivars (Wilhelm and Ester; commercially available in Sweden) were cultivated in contaminated sediment for 5 weeks in a field setting. Heavy metals (Cd, Cu, Pb, Ni and Zn) content in different plant parts (root, cutting, shoot and leaves) were analysed by using atomic absorption spectrophotometer (AAS). The result indicated that the root biomass production was negatively affected for both cultivars due to the contaminated sediment medium, even though no morphological symptoms were present. Both Cd and Cu net accumulation were found to be significantly higher in Ester cultivars. The low translocation of heavy metals in Salix spp. hints that accumulated heavy metals are stored in the root parts. Low translocation of heavy metals from contaminated sediments gives a strong potential for using a growth medium to utilize phosphorus (P) in the sediment from a circular economy and bioeconomy perspective.

Phytoremediation is the most cost effective and applicable technique to clean contaminated soils. The study was carried out in controlled conditions. Cadmium was applied as only cadmium (30 mgkg−1), and together with a chelator as Cd (30 mgkg−1) + EDTA, in triplicates. Chromium was applied as only chromium (10 mg/kg−1), and together with a chelator as Cr (10 mgkg−1) + EDTA. Similarly, lead was applied as only lead (100 mgkg−1), and together with a chelator as Pb (100 mgkg−1) + EDTA. The highest root and shoot dry weights were detected in lead and chromium applied pots. The highest lead, cadmium and chromium concentrations in the shoot of broccoli (Brassica oleracea var.italica) were found to be 14.0 mgkg−1, 6.67 mg kg-1and, 5.17 mg kg−1, respectively, in the chelated applications. The order of accumulation in the root was Cr > Pb > Cd. Broccoli was shown to be effective in phytoextraction of Pb Chromium was especially accumulated in the roots of broccoli which indicated that this plant was successful for phytostabilization of Cr. Broccoli can be employed for both phytostabilization and phytoextraction of cadmium. The results revealed that broccoli played a role in the remediation of lead, chromium and cadmium heavy metals as a hyper accumulator plant.

[Objective] To match the fertilization method in Luzhou tobacco area and the absorption amount of nutrient elements absorbed by tobacco plants, to meet the growth needs of tobacco plants. [Method] In the production stage of flue-cured tobacco in Luzhou tobacco area, samples of different organs were collected at certain intervals, nutrient content and dry matter accumulation were measured, and corresponding fertilization measures were proposed according to the law of nutrient accumulation. [Result] The dry matter accumulation of different organs showed a “S” pattern. The dry matter accumulation of root, stem and leaf significantly increased from 41, 31 and 21 days after transplanting to 70 days, which accounted for 71.45%, 73.69% and 81.97% of the total dry matter accumulation of the corresponding organs, respectively. The maximum rates of root and stem dry matter accumulation were occurred within 10 days after topping, which were 35.06 and 45.27 kg/(hm2·d), while the maximum rates of leaf dry matter accumulation was occurred within 41-50 days after transplanting with a value of 54.92 kg/(hm2·d). The accumulation of nitrogen, phosphorus and potassium in tobacco plants showed "S" regular changes, and increased rapidly from 10-50, 10-70 and 10-50 days after transplanting, respectively, which accounted for 77.17%, 51.13% and 84.64% of the total accumulation. The nitrogen and potassium assimilation rate peaks were occurred during the 31-40 days after transplanting, which were 2.61 and 3.96 kg/(hm2·d). The phosphorus assimilation rate peak was occurred during 51-60 days after transplanting. The partial productivity of different fertilizers was different, which showed that nitrogen fertilizer partial productivity>phosphorus fertilizer partial productivity>potassium fertilizer partial productivity. [Conclusion] In the growth stage of Luzhou flue-cured tobacco, nitrogen and potassium fertilizers should be applied early. Combined with the characteristics of phosphate fertilizer, the one-time fertilization method of flue-cured tobacco production in Luzhou tobacco area could be used during ridging, which is more conducive to the absorption and accumulation of nutritional elements by tobacco plants and balancing the chemical composition of flue-cured tobacco, and ensuring the quality of tobacco leaves. [ABSTRACT FROM AUTHOR]

Rising waste construction, agricultural actions, and manufacturing sewages all contribute to heavy metal accumulation in water resources. Humans consume heavy metals-contaminated substances to make sustenance, which equally ends up in the food circle. Cleaning of these vital properties, along with the prevention of new pollution, has long been required to evade negative strength consequences. Most wastewater treatment techniques are widely acknowledged to be costly and out of the grasp of governments and small pollution mitigation businesses. Utilizing hyper-accumulator plants that are extremely resilient to heavy metals in the environment/soil, phytoremediation is a practical and promising method for eliminating heavy metals from contaminated environments. This method extracts, degrades, or detoxifies harmful metals using green plants. The three phytoremediation techniques of phytostabilization, phytoextraction, and phytovolatilization have been used extensively for soil remediation. Regarding their ability to be used on a wide scale, conventional phytoremediation methods have significant limitations. Hence, biotechnological attempts to change plants for heavy metal phytoremediation methods are extensively investigated in order to increase plant effectiveness and possible use of improved phytoremediation approaches in the country of India. This review focuses on the advances and significance of phytoremediation accompanied by the removal of various harmful heavy metal contaminants. Similarly, sources, heavy metals status in India, impacts on nature and human health, and variables influencing the phytoremediation of heavy metals have all been covered. [ABSTRACT FROM AUTHOR]

This study investigated the accumulation of total phosphorus (TP) and heavy metals (HMs; Pb, Zn, Cu, Cd, Cr, and Ni) in citrus orchard soils in Jeju Island, Korea, identifying potential soil pollution sources using statistical analysis. Anthropogenic HM pollution was evaluated using the geoaccumulation index and enrichment factors, whereas HM bioavailability was assessed via single extraction. TP, Zn, Cu, and Cr concentrations in citrus orchard topsoil were significantly higher than those in forestland soils, indicating their accumulation in the surface layer. Statistical analyses confirmed that elements with high concentrations were closely related to potential pollution sources accumulated on the surface layer of citrus orchards owing to agricultural activities. Particularly, Zn and Cu accumulation was confirmed to originate from intensive compost and pesticide use in citrus orchards. Cu showed the highest contamination and enrichment of all HMs. However, Zn and Cu fractions, determined via an availability assessment, were dominated by acid or complex compounds, indicating that labile Zn and Cu have potential bioavailability for plants. Nevertheless, their fractions accounted for a small proportion (mean < 15%). Therefore, despite the high pollution levels of Zn and Cu, their availabilities were extremely low, indicating a negligible bioavailability in crops and no impact on aquatic ecosystems. [ABSTRACT FROM AUTHOR]

This study which was carried out between July 2019 and April 2020 aimed to determine the seasonal changes of heavy metals (Cd, Cr, Cu, Fe, Mn, Mo, Ni, Pb, Se, and Zn) in plant organs of Phragmites australis and Typha angustifolia grown in Eğirdir Lake and to research the usability of the these plants for phytoremediation with the calculation of bioaccumulation factor (BF). Plant samples were brought to the laboratory, and then washed, cleaned with distilled water, dried in an oven at 70 °C and acidified with 10 ml HNO3. The samples were heated at 120 °C on a hot plate until completely mineralized. After mineralization, heavy metal concentrations were determined by using ICP-AES (Vista model). Only Mo was the highest in leaf, while other metals were highest in root in P. australis. In T. angustifolia, Mn and Mo were highest in the leaf, the accumulation of other metals was observed to be higher in the plant's roots than the other organs. It was discovered that the metal concentrations in root, in stem, and in leaf for both macrophytes generally increased in summer and decreased in root in autumn and winter and in stem and in leaf in spring for P. australis and in all organs in spring for T. angustifolia. Bioaccumulation factor (BF) values were calculated to determine the phytoremediation potential of P. australis and T. angustifolia. Both macrophytes are not excluder for all metals. Plants revealed potential for phytoremediation for the removal of heavy metals especially Mo and Zn. As a result of our study, it was determined that both macrophytes had accumulation abilities especially for Mo and Zn. It should be taken into consideration that these macrophytes can be used for improving the current situation of Eğirdir Lake due to their advantages such as being economical and not causing any harm to the environment. [ABSTRACT FROM AUTHOR]

Lignin is an important secondary metabolite that maintains the mechanical strength of horticultural plants and enhances their ability to respond to external environmental changes such as biotic and abiotic stresses. However, excessive accumulation of lignin can lead to lignification of horticultural products, reducing their taste quality and nutritional value. Therefore, the lignin content of horticultural products needs to be controlled at a reasonable level, and studying and regulating lignin metabolism is very meaningful work. This article focuses on the synthesis, accumulation, and regulation of lignin in horticultural crops in recent years, provides a systematic analysis of its molecular mechanism and application prospects, and sheds insights into the directions that need further research in the future. This article provides an important basis for the regulation of lignin accumulation and lignification in horticultural crops and proposes new ideas for improving the quality of horticultural crops. [ABSTRACT FROM AUTHOR]

The present study made significant contributions to the application of a green approach for removing metals from wastewater using microalgae. Bioelimination, which involoves the use of biological material to accumulate and concentrate pollutants from aqueous solutions enables ecologically an acceptable recovery and/or elimination of these pollutants. This research specifically aimed to evaluate the efficacy of the blue-green alga/cyanobacterium Oscillatoria sp. in the wastewater treatment procedure. The growth rate was promising, especially in low concentrations of wastewater. Additionally, the study explored the potential of using algae for wastewater treatment by reducing the proportion of mineral elements in the algal culture filtrate and examining the possibility of mineral accumulation within the algal cells. Notably, minerals such as phosphate, magnesium, manganese, sodium, iron, sulfur and calcium showed significant differences (P= 0.05) at the probability level. Additionally, it was noted that the highest percentage of mineral nutrient removal was 10% with high efficiency, although in high wastewater concentrations, it was somewhat less efficient. [ABSTRACT FROM AUTHOR]

Technology to enable and support learning and teaching is widespread in university settings. One consequence of such technology use is the accumulation of large volumes of digital data. The acquisition of, and failure to, discard digital content can lead to digital clutter. The potential negative consequences of digital clutter have been examined mainly within a workplace context. Far less is known about how university students manage their academic digital data and whether they have strategies to deal with excessive digital clutter. Eighteen undergraduate students took part in a one-to-one or group-based interview to discuss their digital data management strategies including accumulation and deletion behaviours. Thematic analysis led to three themes: (1) Digital data accumulation across the student journey, (2) Reactive and evolving digital data management strategies and (3) Data overload: Anxiety, loss of productivity and feeling overwhelmed. The findings capture the complexity of feelings students have about different types of digital technology and the strategies they use to manage increasingly large volumes of digital data. Findings are discussed in relation to the need for better support and guidance for students around the use of digital technology to manage their data during their time at university. [ABSTRACT FROM AUTHOR]

A Cd-contaminated paddy field at the Quanzhou County Institute of Agricultural Science in Guilin was selected as the research object, and geo-electrochemical technology (GT) was used to treat the Cd-contaminated paddy field in situ. The technology's effectiveness in removing the heavy metal Cd element from paddy soil and the change rule of Cd accumulation and transport in various parts of rice plants under the action of an electric field were studied. That was to provide a theoretical basis and a new technical choice for remediating paddy soil polluted by Cd. The results showed that the GT effectively removed the heavy metal Cd element from the paddy soil. When the level of soil Cd in the paddy field was 0.58 mg/kg, after in situ treatment with the GT, the soil Cd decreased to 0.39 mg/kg, which met the requirements of soil contamination risk control for agricultural land. Geo-electrochemical technology effectively reduced the content of the Cd element in various tissues and organs of rice plants, made the Cd content in brown rice lower than the requirement of the national food pollutant limit standard of 0.2 mg/kg, and achieved the production of safe rice. Geo-electrochemical technology reduced the enrichment of Cd in the tissues and organs of the rice plants, including roots, stems, leaves, and grains, and at the same time affected the process of rice roots transporting Cd. [ABSTRACT FROM AUTHOR]

Microplastic distribution and pollution as emerging contaminants have become a leading environmental issue globally, owing to their ecological and health implications on biota and humans. Although several bibliometric studies have been reported on microplastics, they are mostly restricted to selected environmental media. As a result, the present study aimed at assessing the literature growth trend of microplastics-related research and their distribution in the environment using a bibliometric approach. The Web of Science Core Collection was explored to retrieve published articles on microplastics from 2006 to 2021, and the data were analysed using the Biblioshiny package of RStudio. This study also highlighted filtration, separation, coagulation, membrane technology, flotation, bionanomaterials, bubble barrier devices, and sedimentation as MP remediation techniques. In the present study, a total of 1118 documents were collected from the literature search; the documents/author and authors/document were 0.308 and 3.25, respectively. A significant growth rate of 65.36% was recorded with notable progress between 2018 and 2021. China, the USA, Germany, the UK, and Italy recorded the highest number of publications within the period under consideration. A collaboration index of 3.32 was also relatively high, with the Netherlands, Malaysia, Iran, France, and Mexico having the highest MCP ratios, respectively. It is anticipated that findings from this study will help the policymakers in addressing issues concerning microplastic pollution assist the researchers in identifying areas to concentrate their studies, and where to seek collaboration in their future research plans. [ABSTRACT FROM AUTHOR]

In this study, we investigated the accumulation and transport patterns of phthalate ester (PAEs) compounds in the soil-plant system of maize and cabbage fields under different film mulching years. The total content of five PAEs in the maize fields soil ranged from 156.19 to 566.1 μg kg−1 with film mulching for 0–20 years. The total content of five PAEs in the cabbage field soils ranged from 252.48 to 559.07 μg kg−1 with film mulching for 0–30 years. The PAEs content in cabbage and maize field soils was lower than the environmental quality standards for soil (GB 15618-2008). With the increase in film mulching years, both maize and cabbage soil PAEs contents increased significantly (p < 0.05), while among the five PAEs, the contents of di-n-butyl phthalate (DnBP) and di(2-ethylhexyl) phthalate (DEHP) increased the most significantly, and the content of DEHP in the soils was the highest. The DEHP content in soils planted with maize ranges from 134.03 to 406.79 μg kg−1 with the film mulching for 20 years; while in soil planted with cabbage, it ranges from 229.35 to 405.2 μg kg−1 with the film mulching for 30 years. The DEHP content in all of the soils has not exceed the limit value established by the USEPA in U.S. Five PAEs were detected in maize seeds and cabbage leaves, among which the DEHP content exceeded the maximum residue limit set by the National Food Safety Standard (GB 9685-2016) for DEHP in food after more than 10 years of mulching. The bioaccumulation and translocation factors in cabbage showed a significant positive correlation with the film mulching years. However, the bioaccumulation factor and translocation factor in maize have weak correlations with the film mulching years, possibly due to the lower PAEs content in the deep soil layers where maize roots are distributed. Our research revealed a significant association between the presence and distribution of PAEs in crops and mulching years. These novel discoveries provide fundamental information for controlling PAEs pollution in agricultural environments. [ABSTRACT FROM AUTHOR]

Arctic warming has accelerated surface melting even in the highland areas of the Greenland ice sheet (GrIS). Understanding the relationship between climate and surface melting is essential for improving the estimates of ice‐sheet mass loss due to warming. Here we analyze a 250 m‐long ice core from the southeastern dome of GrIS (SE‐Dome site; 67°19′17″ N, 36°47′03″ W, 3,161 m a.s.l.), where the annual mean temperature is −20.9°C and the accumulation rate is high and there is a large discrepancy among climate models regarding snow accumulation estimates. A time scale was established for 1799–2020 with a half‐year uncertainty using annual counting of H2O2 concentration and five time horizons determined by electrical conductivity, melt events, and tritium concentration. The annual accumulation rate from the ice core shows no significant trend over 221 years and has an average of 1.04 ± 0.20 m w.e. year−1. In contrast, the frequency and thickness of refrozen melt layer (ML) have increased over 221 years, and are synchronized with temperature changes in the Arctic. The thickness of MLs correlates positively with the time‐integrated summer temperature anomaly using a reanalysis of air temperature. The in‐situ accumulation records in the southeastern GrIS provide an important basis for correcting reanalysis data such as ERA5, which in turn are valuable for improving regional climate models. Plain Language Summary: In recent years, Arctic temperatures have been increasing faster than global temperatures. In the inland Greenland ice sheet (GrIS), the surface snow melts on warm days, then the meltwater percolates in the snowpack and refreezes into melt layers (MLs). Here we describe an ice core, collected from the southeastern GrIS, which contains records of precipitation and MLs from 1799 to 2020. We then compare these results with the climatic data. The annual precipitation rate obtained from the ice core shows neither a decrease nor an increase over 221 years, suggesting no significant trend in the southeastern region. On the other hand, with Arctic warming, the ML thickness per year has increased through the 19th–21st centuries. In addition, there is a positive correlation between ML thickness and summer temperature. We conclude that the annual precipitation rate in southeastern GrIS is constant regardless of Arctic warming and the ice core is favorable for reconstructing environmental records from the pre‐industrial era to the present. Key Points: From an ice core in the southeastern Greenland ice sheet, we establish a time scale spanning 1799–2020 with a half‐year uncertaintyOver 221 years, the annual accumulation rate shows no significant trend, while the melt layer thickness has increased with Arctic warmingThe in‐situ accumulation records provide an important basis for correcting reanalysis data, which in turn are valuable for improving models [ABSTRACT FROM AUTHOR]

Phytoremediation of lead (Pb) in contaminated soils using hyper-enriched plants is an important task. It is a green and sustainable measure. Studies have revealed that three ornamental plants, Tagetes patula (T. patula), Solanum nigrum (S. nigrum), and Mirabilis jalapa (M. jalapa), have the ability to enrich for Pb; however, studies on difference between them and root morphology and the relationship between tolerance and capacity are lacking. The ability of three lead-enriching plants, T. patula, S. nigrum, and M. jalapa, to cope with Pb stress was assessed in hydroponic experiments using five Pb stress concentrations (0–1000 mg/L). Under different Pb stress conditions, the growth of the shoots and roots of three tested ornamental plants was inhibited to varying degrees. In the three tested ornamental plants, Pb mainly accumulated in the roots, and the highest levels of Pb observed in the shoots of T. patula, S. nigrum, and M. jalapa were 1074.1 mg/kg, 958.7 mg/kg, and 975.3 mg/kg, respectively. All plants reached a critical level of Pb hyperaccumulation. Redundancy analysis showed that changes in the root architecture of the three tested ornamental plants were significantly and positively correlated with tolerance as well as the enrichment and transfer ability of the heavy metal Pb. Therefore, these three ornamental plants have the potential to remediate Pb-contaminated water and soil and can increase the tolerance and enrichment characteristics of Pb by regulating the root biomass and root length of the three test ornamental plants via various agronomic measures. In addition, more research should be conducted to assess their effectiveness as phytoextractants under field conditions. [ABSTRACT FROM AUTHOR]

The paper seeks to uncover a long-submerged tradition that saw knowledge accumulation as the main driver of development. This vision was ubiquitous until the late 18th century when, with the advent of the machine age, the focus shifted from knowledge accumulation to capital accumulation. Emphasis on knowledge did not disappear completely. Some argued that the knowledge embedded in human agents and not capital was the source of productivity gains while others emphasised the role of technological and scientific knowledge alongside capital accumulation. By the early decades of the 20th century, the economic role of science had become more salient and by the end of that century, the idea that knowledge accumulation has a central role in progress was again taken for granted. The paper suggests that by focusing the kinds of knowledge we have; and how that knowledge is stored, transmitted, made use of, and extended; we can learn much about how specific social relations of production facilitate or retard development, about who gets the rewards, and how relations of production may need to change to allow knowledge itself to develop. [ABSTRACT FROM AUTHOR]

Soils contaminated with elevated levels of toxic heavy metals affect the soil quality. Phytoremediation is one of the constructive methods used in the mitigation of toxic metals from the soil. A pot experiment was performed by application of eight different concentrations of CCA viz 250, 500, 750, 1,000, 1,250, 1,500, 2,000, and 2,500 mg kg−1 soil to evaluate the efficiency of Acacia mangium and Acacia auriculiformis in phytoremediation of CCA compounds. Results showed that the shoot and root length, height, collar diameter, and biomass of the seedlings were significantly reduced with increase in CCA concentrations. The roots of the seedlings accumulated 1.5- to 2.0-fold higher amounts of CCA than in stem and leaves. The amount of Cr, Cu, and As found in the roots of A. mangium and A. auriculiformis at 2,500 mg CCA were 10.01 and 10.13, 8.51 and 8.84 mg, and 0.18 and 0.33 mg g−1, respectively. Similarly, the amount of Cr, Cu, and As found in stem and leaves were 4.33 and 7.84, 3.51 and 6.62, and 0.10 and 0.11 mg g−1, respectively. The quantity of Cr, Cu, and As found in stem and leaves were 5.95 and 9.00, 4.86 and 7.18, and 0.09 and 0.14 mg g−1, respectively. Overall, the present study advocates potential use of A. mangium and A. auriculiformis in phytoremediation of Cr, Cu, and As contaminated soils. Phytoremediation of soils contaminated with heavy metals is well documented. Interestingly, information on the influence of Acacia tree species in remediation of chromated copper arsenate (CCA) is scanty. We found that the higher concentrations of CCA (1,000–5,000 mg) significantly reduced the seed germination, growth, and biomass of seedlings. Further, the results revealed that accumulation of Cr, Cu, and As were 1.5- to 2-fold higher in roots than in shoots. Present study adds knowledge on efficacy of Acacia mangium and Acacia auriculiformis in phytoremediation of CCA contaminated soils. [ABSTRACT FROM AUTHOR]

A set of direct current (DC) analytical equations is formulated for the analysis and design of a single‐layer thin‐film transistor (TFT). For a specified TFT structure, drain current is calculated as a function of drain and gate voltage (taking the source as ground) according to the Enz, Krummenacher, Vittoz (EKV) compact model. One model parameter function is required to implement this EKV‐based equation, that is, drift mobility as a function of gate voltage. Drift mobility is evaluated as a consequence of accumulation layer electrostatics assessment of the TFT structure specified. In order to implement the model, three semiconductor properties (low‐frequency (static) relative dielectric constant, free electron concentration, and maximum (no trapping) mobility), two structure properties (insulator capacitance density and TFT width‐to‐length ratio), and one physical operating parameter (temperature) must be specified. Optimal TFT mobility performance is achieved when the thickness of the semiconductor channel layer is constrained to be less than 2.22 times the channel layer Debye length such that "short‐base" TFT operation obtains. Additionally, higher mobility TFT performance is obtained by selecting a channel layer with a small electron effective mass, reducing channel layer trap density, reducing channel layer thickness, reducing the free electron concentration, and/or increasing gate capacitance density. [ABSTRACT FROM AUTHOR]

Water-soluble soy protein (SP), which contains many acidic amino acids in its structure, was complexed by mixing with a silane coupling agent, 3-glycidoxypropyltrimethoxysilane (GPTMS). These SP−GPTMS composite materials showed stability in water. This property is due to the cross-linking between SP and GPTMS through the ring cleavage reaction of the epoxy group in the GPTMS molecule and an encapsulation of SP into the 3D siloxane network of GPTMS. When the SP−GPTMS composite material was immersed in an aqueous Cu(II) ion solution, the composite material changed from light brown to blue green by the coordination of Cu(II) ions into the SP. Hence, we evaluated the accumulation of heavy ions, rare-earth ions, and light metal ions. The accumulating affinity of metal ions was Cd(II) << Zn(II), Cu(II), Pb(II) < La(III) < Al(III) < Nd(III), In(III) << Mg(II) < Ca(II) ions. In addition, the sorption capacities of Ca(II), Mg(II), In(III), Nd(III), Al(III), La(III), Pb(II), Cu(II), Zn(II), and Cd(II) ions were 700 nmol/mg, 660 nmol/mg, 470 nmol/mg, 470 nmol/mg, 410 nmol/mg, 380 nmol/mg, 350 nmol/mg, 350 nmol/mg, 300 nmol/mg, and 200 nmol/mg, respectively. These properties suggest that the SP−GPTMS composite material has a divalent light metal ion selectivity. Additionally, the accumulative mechanism of the light metal ions was related to the carboxylate group and the hydroxyl group in the composite material. [ABSTRACT FROM AUTHOR]

Copyright of Acta Agriculturae Zhejiangensis is the property of Acta Agriculturae Zhejiangensis Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Measuring surface mass-balance in the accumulation areas of glaciers is challenging because of the high spatial variability of snow accumulation and the difficulty of conducting annual field glaciological measurements. Here, we propose a method that can solve both these problems for many locations. Ground-penetrating radar measurements and firn cores extracted from a site in the French Alps were first used to reconstruct the topography of a buried end-of-summer snow horizon from a past year. Using these data and surface elevation observations from LiDAR and Global Navigation Satellite System instruments, we calculated the submergence velocities over the period between the buried horizon and more recent surface elevation observations. The differences between the changes in surface elevation and the submergence velocities were then used to calculate the annual surface mass-balances with an accuracy of ±0.34 m w.e. Assuming that the submergence velocities remain stable over several years, the surface mass-balance can be reconstructed for subsequent years from the differences in surface elevation alone. As opposed to the glaciological method that requires substantial fieldwork year after year to provide only point observations, this method, once submergence velocities have been calculated, requires only remote-sensing data to provide spatially distributed annual mass-balances in accumulation areas. [ABSTRACT FROM AUTHOR]

In this article, I show that current literature on authoritarian neoliberalism has not only overlooked the crucial role of legitimation in authoritarian neoliberal regimes, both pre- and post-2008, it has also failed to properly conceptualise it. While existing scholarship mainly pictures neoliberal governments as pursuing legitimation to ensure accumulation remains unopposed, I instead argue that neoliberal governments see legitimation as an instrument of, and precondition for, accumulation – as directly feeding into it. Indeed, my contribution shows that governments aim to transform citizens into neoliberal subjects that actively and willingly participate in neoliberal accumulation. I call this project, which relies on state-driven mass behavioural change, a strategy of 'accumulation by legitimation'. The article illustrates this with the case of Thatcherism, analysing newly released governmental archival sources through a Marxist-Foucauldian framework. I unearth the Thatcher government's propaganda campaign and employee involvement policy, which were a combined effort to influence the British people through governmental education, share ownership as well as communication and consultation in industry. The objective was to turn British workers into self-identifying capitalists that would willingly support the market order and accept its imperatives by themselves, such as the need to moderate their own wage demands. Thatcherites saw this as a prerequisite for their employment and counter-inflationary policies to work. This far-reaching strategy however faced significant obstacles, both from inside government and from British capital, illustrating key contradictions in neoliberalism. While neoliberal ideas endure, this sheds light on the incomplete and fragile character of neoliberal hegemony up to today. [ABSTRACT FROM AUTHOR]

Copyright of Hungarian Medical Journal / Orvosi Hetilap is the property of Akademiai Kiado and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Firebrands, or smoldering and/or flaming particles, are in fact the main culprit to destroy structures in large outdoor fires. A recent comprehensive review of firebrand combustion reported that deposition and subsequent accumulation processes remain largely unexplored. As part of this work, a series of experiments were undertaken to investigate firebrand deposition and accumulation processes in the National Research Institute of Fire and Disaster (NRIFD)'s wind facility. A reduced‐scale firebrand generator was utilized, and various flow obstructions were placed downstream of these firebrand generators to better understand these complex deposition processes. Results of these investigations for multiple wind speeds, firebrand size and mass distributions, and obstacle placement are presented and discussed. [ABSTRACT FROM AUTHOR]

BACKGROUND: The insecticide carbosulfan is usually applied as a soil treatment or seed‐coating agent, and so may be absorbed by crops and pose dietary risks. Understanding the uptake, metabolism and translocation of carbosulfan in crops is conducive to its safe application. In this study, we investigated the distribution of carbosulfan and its toxic metabolites in maize plants at both the tissue and subcellular levels, and explored the uptake and translocation mechanism of carbosulfan. RESULTS: Carbosulfan was mainly taken up by maize roots via the apoplast pathway, was preferentially distributed in cell walls (51.2%–57.0%) and most (85.0%) accumulated in roots with only weak upward translocation. Carbofuran, the main metabolite of carbosulfan in maize plants, was primarily stored in roots. However, carbofuran could be upwardly translocated to shoots and leaves because of its greater distribution in root‐soluble components (24.4%–28.5%) compared with carbosulfan (9.7%–14.5%). This resulted from its greater solubility compared with its parent compound. The metabolite 3‐hydroxycarbofuran was found in shoots and leaves. CONCLUSION: Carbosulfan could be passively absorbed by maize roots, mainly via the apoplastic pathway, and transformed into carbofuran and 3‐hydroxycarbofuran. Although carbosulfan mostly accumulated in roots, its toxic metabolites carbofuran and 3‐hydroxycarbofuran could be detected in shoots and leaves. This implies that there is a risk in the use of carbosulfan as a soil treatment or seed coating. © 2023 Society of Chemical Industry. [ABSTRACT FROM AUTHOR]

Background: Benzothiazole is a potential grain fumigant for Tribolium castaneum. However, its safety profile and suitable fumigation conditions remain unknown. We therefore investigated the insecticidal efficacy, accumulation and dissipation of benzothiazole in grains (wheat, corn and rice) under different temperatures. Results: We established a universal detection method (modified QuEChERS coupled with GC–MS/MS) of benzothiazole residues in three grains, which provided high linearity (R2 > 0.999), sensitivity (limits of detection = 0.001 mg/kg, limits of quantification = 0.002–0.005 mg/kg), accuracy (recoveries = 88.18–118.75%) and precision (relative standard deviations < 4.78%). The insecticidal efficacy order of benzothiazole was 30 ≥ 10 > 20 °C and corn > wheat > rice. Temperature positively affected the accumulation/dissipation rate of benzothiazole. Rice was the most easily accumulated and dissipated grain for benzothiazole residues, while corn accumulated benzothiazole more than wheat but less than rice, with dissipation slower than wheat and rice. Conclusion: Our results provide important references for the application of benzothiazole and other fumigants. © 2023 Society of Chemical Industry. [ABSTRACT FROM AUTHOR]

Nanosilver has a wide range of applications in many industries, including animal production. Its beneficial effects resulting from, among others, antibacterial properties are known; however, some concerns remain related to safety of its use and possible accumulation in the environment and all its components. This study aimed to analyze the content of silver and antagonistic elements (copper, selenium, zinc) in breast and thigh muscles, abdomen skin, liver, lung and blood serum of broilers exposed to a nanosilver-based preparation added to litter. Ross 308 broilers were divided into three groups: control and two experimental (84 birds in each) differing by the amount of preparation addition. The study lasted 24 days, after which the birds were slaughtered and the mentioned samples were collected for laboratory analyses using atomic absorption spectroscopy. An application of preparation based on nanosilver caused an increase in Ag content in chickens' liver, lung and abdomen skin. Cu content decreased in all experimental groups, except for abdomen skin, while Zn content increased in most cases compared to the control. No clear decrease of the increasing tendency was found for Se. It did not demonstrate an antagonism with respect to the content of Cu, Se and Zn in examined samples. [ABSTRACT FROM AUTHOR]