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1,097 results on '"Yao, Masahiro"'

203. In vitro mouse spermatogenesis with an organ culture method in chemically defined medium

Author

Sanjo, Hiroyuki, primary, Komeya, Mitsuru, additional, Sato, Takuya, additional, Abe, Takeru, additional, Katagiri, Kumiko, additional, Yamanaka, Hiroyuki, additional, Ino, Yoko, additional, Arakawa, Noriaki, additional, Hirano, Hisashi, additional, Yao, Tatsuma, additional, Asayama, Yuta, additional, Matsuhisa, Akio, additional, Yao, Masahiro, additional, and Ogawa, Takehiko, additional

Published
2018
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205. Acute and late toxicities in localized prostate cancer patients treated with low-dose 125I brachytherapy (110 Gy) in combination with external beam radiation therapy versus brachytherapy alone (160 Gy)

Author

Makai, Yuki, primary, Hayashi, Narihiko, additional, Koike, Izumi, additional, Kaizu, Hisashi, additional, Takano, Shoko, additional, Sugiura, Madoka, additional, Ito, Eiko, additional, Sato, Mizuki, additional, Uemura, Hiroji, additional, Yao, Masahiro, additional, and Hata, Masaharu, additional

Published
2018
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209. An evaluation to define the role of repeat transurethral resection in a treatment algorithm for non-muscle-invasive bladder cancer

Author

Fujikawa, Atsushi, Yumura, Yasushi, Yao, Masahiro, Tsuchiya, Futoshi, Iwasaki, Akira, and Moriyama, Masatoshi

Subjects
Urinary organs -- Surgery, Bladder cancer -- Development and progression -- Care and treatment -- Research, Health
Abstract

Byline: Atsushi. Fujikawa, Yasushi. Yumura, Masahiro. Yao, Futoshi. Tsuchiya, Akira. Iwasaki, Masatoshi. Moriyama Objective: Repeat transurethral resection (ReTUR) is an effective treatment for non-muscle-invasive bladder cancer (NMIBC) to prevent disease [...]

Published
2012

210. 腎細胞癌心筋転移に対してスニチニブが有効であった1例

Author

Tatenuma, Tomoyuki, Yao, Masahiro, Sakata, Ryoko, Sano, Futoshi, Makiyama, Kazuhide, Nakaigawa, Noboru, Nakayama, Takashi, Inayama, Yoshiaki, and Kubota, Yoshinobu

Subjects
Myocardiac metastasis, 494.9, urologic and male genital diseases, female genital diseases and pregnancy complications, Renal cell carcinoma
Abstract

A 65-year-old male was referred to our clinic from orthopedics because his right gastrocnemius muscle tumor was diagnosed as a metastatic renal cell carcinoma (RCC) with clear cell/spindle cell morphology. He had right nephrectomy for RCC 18 years previously. At 17 months following the first visit to our clinic, brain, lung and right gluteus medius muscle metastases were identified on positron emission tomographycomputed tomography (PET-CT). The echocardiogram for the evaluation of his heart function incidentally revealed a 3 cm nodular lesion in the right ventricular wall suggesting myocardiac metastasis. He started to take sunitinib at a standard dose of 50 mg/day. A subsequent echocardiogram during the 2nd cycle of sunitinib showed complete disappearance of the myocardiac metastasis. After the 2nd cycle, PET-CT revealed a partial response (PR) for the other metastases. He received 8 cycles of sunitinib. The best response was PR, and progression-free survival was 6 months. After that, he took everolimus for 7 months. Although the myocardiac metastasis continued to show a complete response during the treatment course, he died of progressive lung metastases at 21 months following the administration of sunitinib. Diagnosis of myocardiac metastasis of RCC during the treatment course as well as its successful treatment with molecular targeting agents has rarely been reported.

Published
2013

211. A Case of Retroperitoneal Angioleiomyoma Resected by Laparoscopy

Author

Sakata, Ryoko, Makiyama, Kazuhide, Noguchi, Go, Sano, Futoshi, Nakaigawa, Noboru, Yao, Masahiro, Nakayama, Takashi, Yamanaka, Seiji, and Kubota, Yoshinobu

Subjects
Angioleiomyoma, 494.9, Laparoscopic surgery, Retroperitoneal tumor
Abstract

A retroperitoneal angioleiomyoma was incidentally detected in a 56-year-old woman during an examination of cardiovascular disease, and referred to the department of urology. Computed tomography (CT) showed a solid tumor approximately 3 cm in diameter, enhanced heterogeneously adjacent to the right adrenal and renal vein on magnetic resonance imaging the tumor showed a low intensity in the T1-weighted image and high intensity in T2-weighted image. These radiographic findings suggested a retroperitoneal tumor such as paraganglioma, angioma. Furthermore, because she was a carrier of Human Adult T Cell Leukemia Virus-I (HTLV-I) this tumor was suspected to have relevance to malignant lymphoma. We performed laparoscopic surgical excision of the tumor. Pathlogical diagnosis was an angioleiomyoma. Angioleiomyoma is a raretypeof leiomyoma originating from smooth muscleand containing thick-walled vessels. Only a few cases of retroperitoneal angioleiomyoma have been reported.

Published
2012

212. Chemotherapy with Low-Dose Docetaxel and Estramustine Phosphate in Patient with Liver Dysfunction Due to Liver Metastases of Hormone-Refractory Prostate Cancer : A Case Report

Author

Miyake, Miki, Nakaigawa, Noboru, Kita, Kaoru, Yanagisawa, Masahiro, Terao, Hideyuki, Sano, Futoshi, Murakami, Takayuki, Makiyama, Kazuhide, Ogawa, Takehiko, Uemura, Hiroji, Yao, Masahiro, and Kubota, Yoshinobu

Subjects
Hormone-refractory prostate cancer, Docetaxel, 494.9, Multiple liver metastasis
Abstract

A 82-year-old man was referred to our hospital for treatment of hormone-refractory prostate cancer with liver metastases. The obstruction of intrahepatic bile ducts due to the rapid growth of liver metastases induced liver dysfunction. We administered 25 mg/m2 docetaxel on day1 and 280 mg/body estramustine phosphate on day 1 to day 3, every 4 weeks. After two courses of this combined chemothrapy, the liver metastases were markedly reduced in size with the rapid improvement of liver function.

Published
2010

213. Mixed Epithelial and Stromal Tumor of Kidney : A Case Report

Author

Terao, Hideyuki, Makiyama, Kazuhide, Yanagisawa, Masahiro, Miyake, Miki, Sano, Futoshi, Kita, Kaoru, Murakami, Takayuki, Nakaigawa, Noboru, Ogawa, Takehiko, Uemura, Hiroji, Yao, Masahiro, Kubota, Yoshinobu, Inayama, Yoshiaki, and Nagashima, Yoji

Subjects
Benign tumor of kidney, 494.9, Mixed epithelial and stromal tumor (MEST)
Abstract

Mixed epithelial and stromal tumor of kidney (MEST-K) is a rare benign renal tumor that was first described by Michal and Syrucek in 1998. Its frequency is 0.2-0.28% of all the renal tumors. Here, we report an additional case of MEST-K occurring in a 28-year-old woman. The patient visited a hospital with complaints of lumbago and fever caused by pyelonephritis. The computed tomography revealed hydronephrosis and a cystic tumor in the right kidney, and laparoscopic right nephrectomy was performed. The resected kidney contained a cystic lesion with a grayish-white mural nodule, in the lower portion. The entire lesion measured 5 cm in diameter, and the mural nodule 2.5 cm in diameter. Histologically, the cyst was lined with tall columnar and transitional epithelia. The mural nodule showed microcystic architectures lined with tall columnar and transitional epithelia, scattered in a compact stroma. Immunohistochemically, spindle cells in the stroma were positive for smooth muscle-specific actin, and estrogen and progesterone receptors (ERand PR). Based on these findings, the tumor was diagnosed as MEST-K. MEST-K was newly introduced to the WHO classification of renal tumors, with a pathogenesis related to long-term estrogen exposure, because of ERand PRexpression in the stroma. It is important to consider the possibility of this tumor when encountering cases of cystic tumor in middle-aged and older women, and men with a previous history of estrogen administration.

Published
2009

214. S状結腸癌の腎盂尿管転移の1例

Author

Komeya, Mitsuru, Nakaigawa, Noboru, Sano, Futoshi, Kagota, Masayo, Murakami, Takayuki, Makiyama, Kazuhide, Miyoshi, Yasuhide, Ogawa, Takehiko, Uemura, Hiroji, Yao, Masahiro, Nagashima, Yoji, and Kubota, Yoshinobu

Subjects
Metastatic upper urinary tract tumor, 494.9, digestive system diseases, Colon cancer
Abstract

We report a case of colorectal cancer with metastasis to the upper urinary tract. A 56-year-old man had left flankpain. Ultrasonography and computed tomographic (CT) examination demonstrated left hydronephroureter and a soft-tissue structure within the left ureter. Urinary cytology of the left ureter showed class IIIb. We diagnosed him with ureteral cancer and performed left nephroureterectomy. Microscopic examination demonstrated adenocarcinoma located in ureteral and pelvic wall, especially in blood vessels, with intact mucosa and similar to adenocarcinoma of colon cancer. Therefore metastatic upper urinary tract tumor was suspected. Barium enema and positron emission tomography-CT demonstrated sigmoid colon cancer. Biopsy specimen of colon cancer demonstrated adenocarcinoma, which was consistent with the ureteral tumor. Finally we diagnosed him with metastatic upper urinary tract tumor of sigmoid colon cancer.

Published
2009

215. A Case of Sarcomatoid Renal Cell Carcinoma Developed in the Chalked Kidney (Putty Kidney)

Author

Komeya, Mitsuru, Sano, Futoshi, Kagota, Masayo, Murakami, Takayuki, Makiyama, Kazuhide, Miyoshi, Yasuhide, Nakaigawa, Noboru, Ogawa, Takehiko, Uemura, Hiroji, Yao, Masahiro, Ooshiro, Hisashi, Nagashima, Yoji, and Kubota, Yoshinobu

Subjects
Renal tuberculosis, Sarcomatoid renal-cell carcinoma, 494.9, Chalked kidney (putty kidney)
Abstract

A 66-year-old woman, who developed pulmonary tuberculosis at 17 years old, had a high fever in December, 2006. Computed tomographic (CT) scan showed a tumor in the left chalked kidney, which measured 7 cm in diameter with very low enhancement. Laboratory data showed the rise of acute phase reactants (erythrocyte sedimentation rate and c-reactive protein) and severe anemia. The cultures of sputum and urine revealed no Mycobacterium tuberculosis. With the diagnosis of left renal cell carcinoma in the chalked kidney, we performed left radical nephrectomy. Histopathological diagnosis was sarcomatoid renal cell carcinoma. Although sarcomatoid renal cell carcinoma is highly malignant and its prognosis is poor, her post-operative condition has been good without any adjuvant treatments and there have been no recurrent or metastatic lesions for 9 months. The supervention of renal cell carcinoma on renal tuberculosis is rare. The possible effects of tuberculous lesions on the development and progression of renal cell carcinoma are discussed.

Published
2009

217. 前立腺肥大症に伴う排尿障害に対するシロドシンの服用後早期効果に関する多施設共同臨床研究(SELECTIVITY) : Silodosin Early Effectiveness and Safety Multi Center Trial in Yokohama

Author

Ogawa, Takehiko, Uemura, Hiroji, Sano, Futoshi, Hoshino, Kouji, Kita, Kaoru, Hayashi, Narihiko, Kagota, Masayo, Murakami, Takayuki, Makiyama, Kazuhide, Miyoshii, Yasuhide, Nakaigawa, Noboru, Yao, Masahiro, Shimura, Hidetoshi, Furuhata, Akihiko, Fujikawa, Naoya, Shioi, Koichi, Ueki, Teiichiro, Hara, Yoshinori, Saitou, Kiyoshi, Kawakami, Satoshi, Satomi, Yoshiaki, Hattori, Yusuke, Teranishi, Junichi, Kondo, Keiichi, Kishida, Takeshi, Saito, Kazuo, Noguchi, Kazumi, Fujii, Hiroshi, Yamaguchi, Toyoaki, Kinoshita, Yuzo, Nomura, Sakae, Yoshida, Minoru, Sakai, Naoki, Terao, Hideyuki, Matsumoto, Tatsuya, Umemoto, Susumu, Ogo, Yoshiharu, Kobayashi, Kazuki, Noguchi, Sumio, Asakura, Tomoyuki, Kohdaira, Teruo, Iguchi, Kozue, Izumi, Koji, Hirano, Masami, Kanno, Hitomi, Takahashi, Toshihiro, Nukui, Fumihiko, Mokuo, Yasuhiro, Muraoka, Kentaro, Osada, Yutaka, Funahashi, Makoto, Kitami, Kazuo, Sugiura, Shimpei, Ohta, Junichi, Miura, Takeshi, Ishibashi, Yoshio, Masuda, Mitsunobu, Komiya, Atsushi, Suwa, Yutaka, Hashiba, Takafumi, Mitaka, Kunihisa, Kobayashi, Masataka, Ohsaka, Kimito, Takano, Tetsuzo, Tsuchiya, Futoshi, Iwasaki, Akira, Yamashita, Yuzo, Matsuzaki, Junichi, and Kubota, Yoshinobu

Subjects
Benign prostatic hyperplasia, International Prostate Symptom Score, Silodosin, IPSS, Alpha-1 blockers, Lower urinary tract symptoms, 494.9, urologic and male genital diseases
Abstract

Silodosin (URIEF), a new so-called 3rd generation alpha-1 blocker, is widely expected to be effective and useful for lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH), due to its high specificity to alpha-1A receptor. We evaluated the efficacy of Silodosin, on 187 males 50 years old or over with the diagnosis of BPH. Silodosin significantly improved the International Prostate Symptom Score (IPSS) and quality of life (QOL) score from the day after administration was started. Among 166 patients whose data were available for the analysis of efficacy of Silodosin, 77.5% showed apparent subjective improvement. Eighty three patients, who had been taking another alpha-1 blocker but without satisfactory effects, showed almost the same improvements in IPSS and QOL score after switching to Silodosin as the remaining 83 patients who had no preceding treatment with an alpha-1 blocker. The improvements were not only in voiding symptoms but also in storage symptoms. The patients, who had serious storage symptoms, responded rather well to Silodosin and showed significant improvement. Taken together, Silodosin showed a quick effect for improving subjective symptoms and QOL, and was found to be useful for the management of LUTS with BPH., 2006年11月～2007年10月の前立腺肥大症166例(年齢69.9±6.4歳)を対象にシロドシン服用後超早期での有効性を検討した。シロドシン8mg/日を2週間処方し、排尿症状日誌に国際前立腺症状スコア(IPSS)、QOLスコア、BPH impact indexを記入してもらい、効果判定を行った。その結果、IPSSは服用開始後1、2、3日目と低下し、いずれの観察日も開始時と有意差を認め、14日目は更に低下した。QOLスコアも同様に有意な低下を示し、IPSSとQOLスコアの相関関係を認めた。また、α1遮断薬から切り替えた患者とα1遮断薬を初めて服用した患者との比較では、両群とも服用後1日目からIPSSは有意に低下して14日目まで低下し続け、2群間に有意差は認めなかった。14日目の治療判定ではExcellent 25例、Well 99例、Poor 36例であり、Poor例はいずれの観察日もIPSSの低下を認めなかった。IPSSのサブスコアの排尿、蓄尿症状の変化量は服用後1日目より有意に改善し、蓄尿症状重症例においても同様に1日目より有意に改善効果を認めた。副作用は187例中23例(12.3%)に認め、下痢が11例5.9%と最も多く、重篤な副作用は認めず、高齢により高くなる傾向は認めなかった。以上よりシロドシンの早期からの効果が判明し、無効な症例では早い時点で適した薬剤・治療法の提供が可能になると考えた。

Published
2008

219. Management of urethral stricture: High‐pressure balloon dilation versus optical internal urethrotomy

Author

Kumano, Yohei, primary, Kawahara, Takashi, additional, Mochizuki, Taku, additional, Takamoto, Daiji, additional, Takeshima, Teppei, additional, Kuroda, Sinnnosuke, additional, Teranishi, Jun‐ichi, additional, Makiyama, Kazuhide, additional, Miyoshi, Yasuhide, additional, Yumura, Yasushi, additional, Yao, Masahiro, additional, and Uemura, Hiroji, additional

Published
2017
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221. Low-molecular-weight protein tyrosine phosphatase expression as a prognostic factor for men with metastatic hormone-naïve prostate cancer

Author

Ohtaka, Mari, primary, Miyoshi, Yasuhide, additional, Kawahara, Takashi, additional, Ohtake, Shinji, additional, Yasui, Masato, additional, Uemura, Koichi, additional, Yoneyama, Shuko, additional, Hattori, Yusuke, additional, Teranishi, Jun-ichi, additional, Yokomizo, Yumiko, additional, Uemura, Hiroji, additional, Miyamoto, Hiroshi, additional, and Yao, Masahiro, additional

Published
2017
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222. A low psoas muscle volume correlates with a longer hospitalization after radical cystectomy

Author

Saitoh-Maeda, Yoko, primary, Kawahara, Takashi, additional, Miyoshi, Yasuhide, additional, Tsutsumi, Sohgo, additional, Takamoto, Daiji, additional, Shimokihara, Kota, additional, Hayashi, Yuutaro, additional, Mochizuki, Taku, additional, Ohtaka, Mari, additional, Nakamura, Manami, additional, Hattori, Yusuke, additional, Teranishi, Jun-ichi, additional, Yumura, Yasushi, additional, Osaka, Kimito, additional, Ito, Hiroki, additional, Makiyama, Kazuhide, additional, Nakaigawa, Noboru, additional, Yao, Masahiro, additional, and Uemura, Hiroji, additional

Published
2017
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229. Abstract 3527: Clarification of the molecular mechanism for cancer development in Xp11.2 translocation renal cell carcinoma

Author

Baba, Masaya, primary, Huang, Ying, additional, Motoshima, Takanobu, additional, Hasumi, Hisashi, additional, Hasumi, Yukiko, additional, Furuya, Mitsuko, additional, Nagashima, Yoji, additional, Yao, Masahiro, additional, Oike, Yuichi, additional, Kamba, Tomomi, additional, Schmidt, Laura S., additional, and Linehan, W. Marston, additional

Published
2017
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231. Onco-testicular sperm extraction (onco-TESE) for bilateral testicular tumors: two case reports

Author

Tsutsumi, Sohgo, primary, Kawahara, Takashi, additional, Takeshima, Teppei, additional, Chiba, Sawako, additional, Uemura, Koichi, additional, Otani, Masako, additional, Shimokihara, Kota, additional, Hayashi, Yutaro, additional, Mochizuki, Taku, additional, Takamoto, Daiji, additional, Hattori, Yusuke, additional, Teranishi, Jun-ichi, additional, Miyoshi, Yasuhide, additional, Yao, Masahiro, additional, Inayama, Yoshiaki, additional, Yumura, Yasushi, additional, and Uemura, Hiroji, additional

Published
2017
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234. Nivolumab versus everolimus in advanced renal cell carcinoma: Japanese subgroup analysis from the CheckMate 025 study

Author

Tomita, Yoshihiko, primary, Fukasawa, Satoshi, additional, Shinohara, Nobuo, additional, Kitamura, Hiroshi, additional, Oya, Mototsugu, additional, Eto, Masatoshi, additional, Tanabe, Kazunari, additional, Kimura, Go, additional, Yonese, Junji, additional, Yao, Masahiro, additional, Motzer, Robert J., additional, Uemura, Hirotsugu, additional, McHenry, M. Brent, additional, Berghorn, Elmer, additional, and Ozono, Seiichiro, additional

Published
2017
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235. MP05-19 OUTCOMES OF TREATMENT FOR LOCALIZED PROSTATE CANCER IN A SINGLE INSTITUTION; COMPARISON OF RADICAL PROSTATECTOMY VS RADIATION THERAPY ~PROPENSITY SCORE MATCHING ANALYSIS~

Author

Hayashi, Narihiko, primary, Yokomizo, Yumiko, additional, Osaka, Kimito, additional, Hasumi, Hisashi, additional, Makiyama, Kazuhide, additional, Kondo, Keiichi, additional, Nakaigawa, Noboru, additional, Yao, Masahiro, additional, Ito, Eiko, additional, Sugiura, Madoka, additional, Takano, Shoko, additional, Mukai, Yuki, additional, Kasuya, Takeo, additional, and Taguri, Masataka, additional

Published
2017
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236. Measurement of serum isoform [–2]proPSA derivatives shows superior accuracy to magnetic resonance imaging in the diagnosis of prostate cancer in patients with a total prostate-specific antigen level of 2–10 ng/ml

Author

Furuya, Kazuhiro, primary, Kawahara, Takashi, additional, Narahara, Masaki, additional, Tokita, Takashi, additional, Fukui, Sachi, additional, Imano, Masashi, additional, Mitome, Taku, additional, Ito, Yusuke, additional, Izumi, Koji, additional, Osaka, Kimito, additional, Yokomizo, Yumiko, additional, Hayashi, Narihiko, additional, Hasumi, Hisashi, additional, Nawata, Shintaro, additional, Kawano, Tsuyoshi, additional, Yao, Masahiro, additional, and Uemura, Hiroji, additional

Published
2017
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237. VHL promotes immune response against renal cell carcinoma via NF-κB–dependent regulation of VCAM-1

Author

Labrousse-Arias, David, primary, Martínez-Alonso, Emma, additional, Corral-Escariz, María, additional, Bienes-Martínez, Raquel, additional, Berridy, Jaime, additional, Serrano-Oviedo, Leticia, additional, Conde, Elisa, additional, García-Bermejo, María-Laura, additional, Giménez-Bachs, José M., additional, Salinas-Sánchez, Antonio S., additional, Sánchez-Prieto, Ricardo, additional, Yao, Masahiro, additional, Lasa, Marina, additional, and Calzada, María J., additional

Published
2017
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238. The usefullness of low-molecular-weight protein tyrosine phosphatase as a prognostic factor in metastatic hormone-sensitive prostate cancer.

Author

Ohtaka, Mari, primary, Kawahara, Takashi, additional, Yasui, Masato, additional, Uemura, Kouichi, additional, Yoneyama, Shuko, additional, Mochizuki, Taku, additional, Hattori, Yusuke, additional, Teranishi, Jun-ichi, additional, Yumura, Yasushi, additional, Yokomizo, Yumiko, additional, Uemura, Hiroji, additional, Miyamoto, Hiroshi, additional, Yao, Masahiro, additional, and Miyoshi, Yasuhide, additional

Published
2017
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239. The acceleration of glucose accumulation in renal cell carcinoma assessed by FDG PET/CT demonstrated acquisition of resistance to tyrosine kinase inhibitor therapy

Author

Nakaigawa, Noboru, primary, Kondo, Keiichi, additional, Ueno, Daiki, additional, Namura, Kazuhiro, additional, Makiyama, Kazuhide, additional, Kobayashi, Kazuki, additional, Shioi, Koichi, additional, Ikeda, Ichiro, additional, Kishida, Takeshi, additional, Kaneta, Tomohiro, additional, Minamimoto, Ryogo, additional, Tateishi, Ukihide, additional, Inoue, Tomio, additional, and Yao, Masahiro, additional

Published
2017
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240. Neutrophil-to-Lymphocyte Ratio Predicts Prognosis in Castration-Resistant Prostate Cancer Patients Who Received Cabazitaxel Chemotherapy

Author

Uemura, Koichi, primary, Kawahara, Takashi, additional, Yamashita, Daisuke, additional, Jikuya, Ryosuke, additional, Abe, Koichi, additional, Tatenuma, Tomoyuki, additional, Yokomizo, Yumiko, additional, Izumi, Koji, additional, Teranishi, Jun-ichi, additional, Makiyama, Kazuhide, additional, Yumura, Yasushi, additional, Kishida, Takeshi, additional, Udagawa, Koichi, additional, Kobayashi, Kazuki, additional, Miyoshi, Yasuhide, additional, Yao, Masahiro, additional, and Uemura, Hiroji, additional

Published
2017
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241. A Low Psoas Muscle Index before Treatment Can Predict a Poorer Prognosis in Advanced Bladder Cancer Patients Who Receive Gemcitabine and Nedaplatin Therapy

Author

Kasahara, Ryo, primary, Kawahara, Takashi, additional, Ohtake, Shinji, additional, Saitoh, Yoko, additional, Tsutsumi, Sohgo, additional, Teranishi, Jun-ichi, additional, Miyoshi, Yasuhide, additional, Nakaigawa, Noboru, additional, Yao, Masahiro, additional, Kobayashi, Kazuki, additional, and Uemura, Hiroji, additional

Published
2017
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242. The neutrophil-to-lymphocyte ratio is an effective prognostic marker in localized upper urinary tract urothelial carcinoma treated with nephroureterectomy

Author

Ohtaka, Mari, primary, Kawahara, Takashi, additional, Mochizuki, Taku, additional, Ishida, Hiroaki, additional, Kuroda, Shinnnosuke, additional, Shinbori, Moeka, additional, Hattori, Yusuke, additional, Teranishi, Jun-ichi, additional, Makiyama, Kazuhide, additional, Miyoshi, Yasuhide, additional, Yumura, Yasushi, additional, Miyamoto, Hiroshi, additional, Yao, Masahiro, additional, and Uemura, Hiroji, additional

Published
2017
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244. RANK/RANKL expression in prostate cancer

Author

Ohtaka, Mari, primary, Kawahara, Takashi, additional, Mochizuki, Taku, additional, Takamoto, Daiji, additional, Hattori, Yusuke, additional, Teranishi, Jun-ichi, additional, Miyoshi, Yasuhide, additional, Yumura, Yasushi, additional, Hasumi, Hisashi, additional, Yokomizo, Yumiko, additional, Hayashi, Narihiko, additional, Kondo, Keiichi, additional, Yao, Masahiro, additional, Miyamoto, Hiroshi, additional, and Uemura, Hiroji, additional

Published
2017
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245. Development of Database and Genomic Medicine for von Hippel-Lindau Disease in Japan

Author

TAKAYANAGI, Shunsaku, primary, MUKASA, Akitake, additional, NAKATOMI, Hirofumi, additional, KANNO, Hiroshi, additional, KURATSU, Jun-ichi, additional, NISHIKAWA, Ryo, additional, MISHIMA, Kazuhiko, additional, NATSUME, Atushi, additional, WAKABAYASHI, Toshihiko, additional, HOUKIN, Kiyohiro, additional, TERASAKA, Shunsuke, additional, YAO, Masahiro, additional, SHINOHARA, Nobuo, additional, SHUIN, Taro, additional, and SAITO, Nobuhito, additional

Published
2017
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246. Foreign body in the bladder: A case report

Author

Shimokihara, Kota, primary, Kawahara, Takashi, additional, Hayashi, Yutaro, additional, Tsutsumi, Sohgo, additional, Takamoto, Daiji, additional, Mochizuki, Taku, additional, Hattori, Yusuke, additional, Teranishi, Jun-ichi, additional, Miyoshi, Yasuhide, additional, Yumura, Yasushi, additional, Yao, Masahiro, additional, and Uemura, Hiroji, additional

Published
2017
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247. H255Y and K508R missense mutations in tumour suppressorfolliculin (FLCN)promote kidney cell proliferation

Author

Hasumi, Hisashi, primary, Hasumi, Yukiko, additional, Baba, Masaya, additional, Nishi, Hafumi, additional, Furuya, Mitsuko, additional, Vocke, Cathy D., additional, Lang, Martin, additional, Irie, Nobuko, additional, Esumi, Chiharu, additional, Merino, Maria J., additional, Kawahara, Takashi, additional, Isono, Yasuhiro, additional, Makiyama, Kazuhide, additional, Warner, Andrew C., additional, Haines, Diana C., additional, Wei, Ming-Hui, additional, Zbar, Berton, additional, Hagenau, Herbert, additional, Feigenbaum, Lionel, additional, Kondo, Keiichi, additional, Nakaigawa, Noboru, additional, Yao, Masahiro, additional, Metwalli, Adam R., additional, Marston Linehan, W., additional, and Schmidt, Laura S., additional

Published
2016
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250. Propiverine hydrochloride improved correlatively subjective QOL and objective findings in Japanese patients with urinary frequency and/or incontinence

Author

Noguchi, Kazumi, Yamagishi, Takuya, Suzuki, Kotaro, Kondo, Keiichi, Kishida, Takeshi, Saito, Kazuo, Sekiguchi, Yuki, Nakaigawa, Noboru, Ogawa, Takehiko, Uemura, Hiroji, Yao, Masahiro, Kubota, Yoshinobu, Kawai, Masaki, Okajima, Kazuto, Kobayashi, Kazuki, Moriyama, Masatoshi, Kinoshita, Yuzo, Mikata, Kunihisa, Kitami, Kazuo, Masuda, Mitsunobu, Saito, Ryuichi, Murai, Tetsuo, Tomoda, Takeshi, Noguchi, Sumio, Sakai, Naoki, Hamano, Atsushi, Nomura, Sakae, and Sato, Kazuhiko

Subjects
QOL, Propiverine hydrochloride, Urinary frequency, 494.9, Urinary ncontinence
Abstract

キング健康調査票(KHQ), international consultation on incontinence-questionnaire:short form(ICIQ-SF)を用いて, 塩酸プロピベリンの頻尿・尿失禁に対する治療効果とQOLスコアの改善度との相関性を検討した.1)評価可能であった68例で, 8週間の投与後, 頻尿・尿失禁が有意に改善されていた.投与後, 尿意切迫感の有症状患者数は有意に減少し, 切迫感の強さも84%が改善した.2)尿失禁の形態では, 腹圧性の症状よりも切迫性尿失禁と考えられる症状の改善傾向が明らかになった.3)有害事象は32%に認められたが, 重篤なものはなかった.4)治療8週後の昼間尿失禁回数の治療効果と, KHQスコアの「仕事・家事の制限」の改善度, および「心の問題」の向上との間, 治療4週後の昼間尿失禁回数の治療効果とICIQスコアの「生活への影響」の改善度との間に相関関係を認めた.5)治療8週後の昼間排尿回数の治療効果と, ICIQスコアの「尿失禁の量」「生活への影響」「合計スコア」の改善度との間にはそれぞれ相関関係が認められた, To investigate how urinary frequency and incontinence affect the patient's subjective quality of life (QOL) and whether an improvement in objective findings by medical treatment affects his/her subjective QOL, a voiding diary using the King's Health Questionnaire (KHQ) and International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) was delivered to patients with urinary frequency and/or incontinence before and after treatment with propiverine hydrochloride for 8 weeks. Sixty-eight patients completed the diary and the questionnaires. Objective symptoms decreased significantly with respect to the mean frequency of urination and to the mean incidence of urinary incontinence. The KHQ and ICIQ-SF scores improved significantly with respect to all domains except personal relationships in the KHQ. In the KHQ, furthermore, a significant correlation was found between decreased incidence of urinary incontinence and improvement in role limitations and between decreased incidence of urinary incontinence and improvement in emotional problems. In the ICIQ-SF, a significant correlation was found between decreased incidence of urinary frequency and subjective improvement in quantity of leakage, between decreased incidence of urinary frequency and improvement in subjective QOL scores, between decreased incidence of urinary frequency and improvement in the total ICIQ-SF score, and between decreased incidence of urinary incontinence and improvement in subjective QOL scores. Thirty-two episodes of adverse reactions were observed. None of them were serious. These results suggest that an improvement in objective symptoms with propiverine hydrochloride favorably improves subjective QOL of the patient, and provide further evidence about the safety and efficacy of propiverine hydrochloride.

Published
2006

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