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Using the atomic cluster expansion (ACE) framework, we develop a machine learning interatomic potential for fast and accurately modelling the phonon transport properties of wurtzite aluminum nitride. The predictive power of the ACE potential against density functional theory (DFT) is demonstrated across a broad range of properties of w-AlN, including ground-state lattice parameters, specific heat capacity, coefficients of thermal expansion, bulk modulus, and harmonic phonon dispersions. Validation of lattice thermal conductivity is further carried out by comparing the ACE-predicted values to the DFT calculations and experiments, exhibiting the overall capability of our ACE potential in sufficiently describing anharmonic phonon interactions. As a practical application, we perform a lattice dynamics analysis using the potential to unravel the effects of biaxial strains on thermal conductivity and phonon properties of w-AlN, which is identified as a significant tuning factor for near-junction thermal design of w-AlN-based electronics.

The previous smart contract code comment (SCC) generation approaches can be divided into two categories: fine-tuning paradigm-based approaches and information retrieval-based approaches. However, for the fine-tuning paradigm-based approaches, the performance may be limited by the quality of the gathered dataset for the downstream task and they may have knowledge-forgetting issues. While for the information retrieval-based approaches, it is difficult for them to generate high-quality comments if similar code does not exist in the historical repository. Therefore we want to utilize the domain knowledge related to SCC generation in large language models (LLMs) to alleviate the disadvantages of these two types of approaches. In this study, we propose an approach SCCLLM based on LLMs and in-context learning. Specifically, in the demonstration selection phase, SCCLLM retrieves the top-k code snippets from the historical corpus by considering syntax, semantics, and lexical information. In the in-context learning phase, SCCLLM utilizes the retrieved code snippets as demonstrations, which can help to utilize the related knowledge for this task. We select a large corpus from a smart contract community Etherscan.io as our experimental subject. Extensive experimental results show the effectiveness of SCCLLM when compared with baselines in automatic evaluation and human evaluation.

The fluid dynamics of liquid droplet impact on surfaces hold significant relevance to various industrial applications. However, high impact velocities introduce compressible effects, leading to material erosion. A gap in understanding and modeling these effects has motivated this study. We simulated droplet impacts on surfaces and proposed a new analytical model for impact pressure and droplet turning line, targeting at predictions for enhanced cavitation. The highly compressed liquid behind the droplet expands sideways, causing lateral jetting. As the droplet encounters a shock wave, it reflects as a rarefaction wave, leading to low-pressure zones within the droplet. These zones converge at the droplet's center, causing cavitation, which, upon collapse, induces another shock wave, contributing to erosion. Using the well-established model for the low-velocity impact shows a significant discrepancy. Hence, an analytical model for the turning line radius is introduced, incorporating the lateral jetting's characteristic length scale. Comparing our model with existing ones, our new model exhibits superior predictive accuracy.

Stain variation is a unique challenge associated with automated analysis of digital pathology. Numerous methods have been developed to improve the robustness of machine learning methods to stain variation, but comparative studies have demonstrated limited benefits to performance. Moreover, methods to handle stain variation were largely developed for H&E stained data, with evaluation generally limited to classification tasks. Here we propose Stain Consistency Learning, a novel framework combining stain-specific augmentation with a stain consistency loss function to learn stain colour invariant features. We perform the first, extensive comparison of methods to handle stain variation for segmentation tasks, comparing ten methods on Masson's trichrome and H&E stained cell and nuclei datasets, respectively. We observed that stain normalisation methods resulted in equivalent or worse performance, while stain augmentation or stain adversarial methods demonstrated improved performance, with the best performance consistently achieved by our proposed approach. The code is available at: https://github.com/mlyg/stain_consistency_learning

Denoising Diffusion models have exhibited remarkable capabilities in image generation. However, generating high-quality samples requires a large number of iterations. Knowledge distillation for diffusion models is an effective method to address this limitation with a shortened sampling process but causes degraded generative quality. Based on our analysis with bias-variance decomposition and experimental observations, we attribute the degradation to the spatial fitting error occurring in the training of both the teacher and student model. Accordingly, we propose $\textbf{S}$patial $\textbf{F}$itting-$\textbf{E}$rror $\textbf{R}$eduction $\textbf{D}$istillation model ($\textbf{SFERD}$). SFERD utilizes attention guidance from the teacher model and a designed semantic gradient predictor to reduce the student's fitting error. Empirically, our proposed model facilitates high-quality sample generation in a few function evaluations. We achieve an FID of 5.31 on CIFAR-10 and 9.39 on ImageNet 64$\times$64 with only one step, outperforming existing diffusion methods. Our study provides a new perspective on diffusion distillation by highlighting the intrinsic denoising ability of models. Project link: \url{https://github.com/Sainzerjj/SFERD}., Comment: AAAI 2024

Effectively leveraging multimodal data such as various images, laboratory tests and clinical information is gaining traction in a variety of AI-based medical diagnosis and prognosis tasks. Most existing multi-modal techniques only focus on enhancing their performance by leveraging the differences or shared features from various modalities and fusing feature across different modalities. These approaches are generally not optimal for clinical settings, which pose the additional challenges of limited training data, as well as being rife with redundant data or noisy modality channels, leading to subpar performance. To address this gap, we study the robustness of existing methods to data redundancy and noise and propose a generalized dynamic multimodal information bottleneck framework for attaining a robust fused feature representation. Specifically, our information bottleneck module serves to filter out the task-irrelevant information and noises in the fused feature, and we further introduce a sufficiency loss to prevent dropping of task-relevant information, thus explicitly preserving the sufficiency of prediction information in the distilled feature. We validate our model on an in-house and a public COVID19 dataset for mortality prediction as well as two public biomedical datasets for diagnostic tasks. Extensive experiments show that our method surpasses the state-of-the-art and is significantly more robust, being the only method to remain performance when large-scale noisy channels exist. Our code is publicly available at https://github.com/BII-wushuang/DMIB., Comment: WACV 2024

Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) is the only in vivo method to non-invasively examine the microstructure of the human heart. Current research in DT-CMR aims to improve the understanding of how the cardiac microstructure relates to the macroscopic function of the healthy heart as well as how microstructural dysfunction contributes to disease. To get the final DT-CMR metrics, we need to acquire diffusion weighted images of at least 6 directions. However, due to DWI's low signal-to-noise ratio, the standard voxel size is quite big on the scale for microstructures. In this study, we explored the potential of deep-learning-based methods in improving the image quality volumetrically (x4 in all dimensions). This study proposed a novel framework to enable volumetric super-resolution, with an additional model input of high-resolution b0 DWI. We demonstrated that the additional input could offer higher super-resolved image quality. Going beyond, the model is also able to super-resolve DWIs of unseen b-values, proving the model framework's generalizability for cardiac DWI superresolution. In conclusion, we would then recommend giving the model a high-resolution reference image as an additional input to the low-resolution image for training and inference to guide all super-resolution frameworks for parametric imaging where a reference image is available., Comment: Accepted by SPIE Medical Imaging 2024

Diffusion Probabilistic Models stand as a critical tool in generative modelling, enabling the generation of complex data distributions. This family of generative models yields record-breaking performance in tasks such as image synthesis, video generation, and molecule design. Despite their capabilities, their efficiency, especially in the reverse process, remains a challenge due to slow convergence rates and high computational costs. In this paper, we introduce an approach that leverages continuous dynamical systems to design a novel denoising network for diffusion models that is more parameter-efficient, exhibits faster convergence, and demonstrates increased noise robustness. Experimenting with Denoising Diffusion Probabilistic Models (DDPMs), our framework operates with approximately a quarter of the parameters, and $\sim$ 30\% of the Floating Point Operations (FLOPs) compared to standard U-Nets in DDPMs. Furthermore, our model is notably faster in inference than the baseline when measured in fair and equal conditions. We also provide a mathematical intuition as to why our proposed reverse process is faster as well as a mathematical discussion of the empirical tradeoffs in the denoising downstream task. Finally, we argue that our method is compatible with existing performance enhancement techniques, enabling further improvements in efficiency, quality, and speed., Comment: 23 pages, 14 figures, Accepted at Transactions of Machine Learning Research (04/2024)

Context: Pre-trained models (PTMs) have demonstrated significant potential in automatic code translation. However, the vulnerability of these models in translation tasks, particularly in terms of syntax, has not been extensively investigated. Objective: To fill this gap, our study aims to propose a novel approach CoTR to assess and improve the syntactic adversarial robustness of PTMs in code translation. Method: CoTR consists of two components: CoTR-A and CoTR-D. CoTR-A generates adversarial examples by transforming programs, while CoTR-D proposes a semantic distance-based sampling data augmentation method and adversarial training method to improve the model's robustness and generalization capabilities. The Pass@1 metric is used by CoTR to assess the performance of PTMs, which is more suitable for code translation tasks and offers a more precise evaluation in real world scenarios. Results: The effectiveness of CoTR is evaluated through experiments on real world Java to Python datasets. The results demonstrate that CoTR-A can significantly reduce the performance of existing PTMs, while CoTR-D effectively improves the robustness of PTMs. Conclusion: Our study identifies the limitations of current PTMs, including large language models, in code translation tasks. It highlights the potential of CoTR as an effective solution to enhance the robustness of PTMs for code translation tasks., Comment: under review

The 3D geometry of high-redshift galaxies remains poorly understood. We build a differentiable Bayesian model and use Hamiltonian Monte Carlo to efficiently and robustly infer the 3D shapes of star-forming galaxies in JWST-CEERS observations with $\log M_*/M_{\odot}=9.0-10.5$ at $z=0.5-8.0$. We reproduce previous results from HST-CANDELS in a fraction of the computing time and constrain the mean ellipticity, triaxiality, size and covariances with samples as small as $\sim50$ galaxies. We find high 3D ellipticities for all mass-redshift bins suggesting oblate (disky) or prolate (elongated) geometries. We break that degeneracy by constraining the mean triaxiality to be $\sim1$ for $\log M_*/M_{\odot}=9.0-9.5$ dwarfs at $z>1$ (favoring the prolate scenario), with significantly lower triaxialities for higher masses and lower redshifts indicating the emergence of disks. The prolate population traces out a ``banana'' in the projected $b/a-\log a$ diagram with an excess of low $b/a$, large $\log a$ galaxies. The dwarf prolate fraction rises from $\sim25\%$ at $z=0.5-1.0$ to $\sim50-80\%$ at $z=3-8$. If these are disks, they cannot be axisymmetric but instead must be unusually oval (triaxial) unlike local circular disks. We simultaneously constrain the 3D size-mass relation and its dependence on 3D geometry. High-probability prolate and oblate candidates show remarkably similar S\'ersic indices ($n\sim1$), non-parametric morphological properties and specific star formation rates. Both tend to be visually classified as disks or irregular but edge-on oblate candidates show more dust attenuation. We discuss selection effects, follow-up prospects and theoretical implications., Comment: Accepted version to appear in ApJ, main body is 36 pages of which ~half are full-page figures

Thorax disease analysis in large-scale, multi-centre, and multi-scanner settings is often limited by strict privacy policies. Federated learning (FL) offers a potential solution, while traditional parameter-based FL can be limited by issues such as high communication costs, data leakage, and heterogeneity. Distillation-based FL can improve efficiency, but it relies on a proxy dataset, which is often impractical in clinical practice. To address these challenges, we introduce a data-free distillation-based FL approach FedKDF. In FedKDF, the server employs a lightweight generator to aggregate knowledge from different clients without requiring access to their private data or a proxy dataset. FedKDF combines the predictors from clients into a single, unified predictor, which is further optimized using the learned knowledge in the lightweight generator. Our empirical experiments demonstrate that FedKDF offers a robust solution for efficient, privacy-preserving federated thorax disease analysis., Comment: Accepted by the IEEE EMBS International Conference on Data Science and Engineering in Healthcare, Medicine & Biology

Both accuracy and timeliness are key factors in detecting fake news on social media. However, most existing methods encounter an accuracy-timeliness dilemma: Content-only methods guarantee timeliness but perform moderately because of limited available information, while social context-based ones generally perform better but inevitably lead to latency because of social context accumulation needs. To break such a dilemma, a feasible but not well-studied solution is to leverage social contexts (e.g., comments) from historical news for training a detection model and apply it to newly emerging news without social contexts. This requires the model to (1) sufficiently learn helpful knowledge from social contexts, and (2) be well compatible with situations that social contexts are available or not. To achieve this goal, we propose to absorb and parameterize useful knowledge from comments in historical news and then inject it into a content-only detection model. Specifically, we design the Comments Assisted Fake News Detection method (CAS-FEND), which transfers useful knowledge from a comments-aware teacher model to a content-only student model during training. The student model is further used to detect newly emerging fake news. Experiments show that the CAS-FEND student model outperforms all content-only methods and even those with 1/4 comments as inputs, demonstrating its superiority for early detection., Comment: 14 pages, 8 figures, 8 tables

We test the relationship between UV-derived star formation rates (SFRs) and the 7.7 ${\mu}$m polycyclic aromatic hydrocarbon (PAH) luminosities from the integrated emission of galaxies at z ~ 0 - 2. We utilize multi-band photometry covering 0.2 - 160 ${\mu}$m from HST, CFHT, JWST, Spitzer, and Herschel for galaxies in the Cosmic Evolution Early Release Science (CEERS) Survey. We perform spectral energy distribution (SED) modeling of these data to measure dust-corrected far-UV (FUV) luminosities, $L_{FUV}$, and UV-derived SFRs. We then fit SED models to the JWST/MIRI 7.7 - 21 ${\mu}$m CEERS data to derive rest-frame 7.7 ${\mu}$m luminosities, $L_{770}$, using the average flux density in the rest-frame MIRI F770W bandpass. We observe a correlation between $L_{770}$ and $L_{FUV}$, where log $L_{770}$ is proportional to (1.27+/-0.04) log $L_{FUV}$. $L_{770}$ diverges from this relation for galaxies at lower metallicities, lower dust obscuration, and for galaxies dominated by evolved stellar populations. We derive a "single-wavelength" SFR calibration for $L_{770}$ which has a scatter from model estimated SFRs (${{\sigma}_{{\Delta}SFR}}$) of 0.24 dex. We derive a "multi-wavelength" calibration for the linear combination of the observed FUV luminosity (uncorrected for dust) and the rest-frame 7.7 ${\mu}$m luminosity, which has a scatter of ${{\sigma}_{{\Delta}SFR}}$ = 0.21 dex. The relatively small decrease in ${\sigma}$ suggests this is near the systematic accuracy of the total SFRs using either calibration. These results demonstrate that the rest-frame 7.7 ${\mu}$m emission constrained by JWST/MIRI is a tracer of the SFR for distant galaxies to this accuracy, provided the galaxies are dominated by star-formation with moderate-to-high levels of attenuation and metallicity., Comment: 20 pages, 11 figures, 2 tables, submitted to ApJ

We propose a novel Deep Active Learning (DeepAL) model-3D Wasserstein Discriminative UNet (WD-UNet) for reducing the annotation effort of medical 3D Computed Tomography (CT) segmentation. The proposed WD-UNet learns in a semi-supervised way and accelerates learning convergence to meet or exceed the prediction metrics of supervised learning models. Our method can be embedded with different Active Learning (AL) strategies and different network structures. The model is evaluated on 3D lung airway CT scans for medical segmentation and show that the use of uncertainty metric, which is parametrized as an input of query strategy, leads to more accurate prediction results than some state-of-the-art Deep Learning (DL) supervised models, e.g.,3DUNet and 3D CEUNet. Compared to the above supervised DL methods, our WD-UNet not only saves the cost of annotation for radiologists but also saves computational resources. WD-UNet uses a limited amount of annotated data (35% of the total) to achieve better predictive metrics with a more efficient deep learning model algorithm.

Anisotropic thermal transport plays a key role in both theoretical study and engineering practice of heat transfer, but accurately measuring anisotropic thermal conductivity remains a significant challenge. To address this issue, we propose the three-sensor 2{\omega} method in this study, which is capable of accurately measuring the isotropic or anisotropic thermal conductivity of solid materials. In this method, several three-sensor groups following the design guidelines are fabricated upon the sample along different characteristic directions, and each group consists of three parallel metal sensors with unequal widths and distances optimally designed based on sensitivity analysis. Among the three sensors, the outer two serve as AC heaters and the middle one as a DC detector. The 2{\omega} voltage signals across the detector in each three-sensor group are measured, and then the data are processed by the proposed Intersection Method to derive the thermal conductivities along directions of interest. The application of the detector's 2{\omega} instead of the heater's 3{\omega} voltage signals eliminates the errors introduced by the uncertainties of thermal resistance in superficial structures (metal layer, insulation layer, interface, etc.). Meanwhile, by replacing the fitting algorithm with the Intersection Method, the local optimum trap of multivariate fitting is avoided. To verify the accuracy and reliability, four typical monocrystalline semiconductors, i.e., Si, GaN, AlN, and {\beta -Ga _2 O _3}, are measured, and the results are consistent with the literature. This method will provide a comprehensive and versatile solution for the thermal conductivity measurements of solid materials., Comment: 25 pages, 6 figures

We provide a probabilistic proof of the fundamental gap estimate for Schr\"odinger operators in convex domains on the sphere, which extends the probabilistic proof of F. Gong, H. Li, and D. Luo for the Euclidean case. Our results further generalize the results achieved for the Laplacian by S. Seto, L. Wang, and G. Wei, as well as by C. He, G. Wei, and Qi S. Zhang. The essential ingredient in our analysis is the reflection coupling method on Riemannian manifolds., Comment: To appear in Trans. Amer. Math. Soc

Quantitative cardiac magnetic resonance T1 and T2 mapping enable myocardial tissue characterisation but the lengthy scan times restrict their widespread clinical application. We propose a deep learning method that incorporates a time dependency Latent Transformer module to model relationships between parameterised time frames for improved reconstruction from undersampled data. The module, implemented as a multi-resolution sequence-to-sequence transformer, is integrated into an encoder-decoder architecture to leverage the inherent temporal correlations in relaxation processes. The presented results for accelerated T1 and T2 mapping show the model recovers maps with higher fidelity by explicit incorporation of time dynamics. This work demonstrates the importance of temporal modelling for artifact-free reconstruction in quantitative MRI.

This study proposes a pipeline that incorporates a novel style transfer model and a simultaneous super-resolution and segmentation model. The proposed pipeline aims to enhance diffusion tensor imaging (DTI) images by translating them into the late gadolinium enhancement (LGE) domain, which offers a larger amount of data with high-resolution and distinct highlighting of myocardium infarction (MI) areas. Subsequently, the segmentation task is performed on the LGE style image. An end-to-end super-resolution segmentation model is introduced to generate high-resolution mask from low-resolution LGE style DTI image. Further, to enhance the performance of the model, a multi-task self-supervised learning strategy is employed to pre-train the super-resolution segmentation model, allowing it to acquire more representative knowledge and improve its segmentation performance after fine-tuning. https: github.com/wlc2424762917/Med_Img, Comment: 6 pages, 8 figures, conference, accepted by SIPAIM2023

Since the onset of the COVID-19 pandemic in 2019, there has been a concerted effort to develop cost-effective, non-invasive, and rapid AI-based tools. These tools were intended to alleviate the burden on healthcare systems, control the rapid spread of the virus, and enhance intervention outcomes, all in response to this unprecedented global crisis. As we transition into a post-COVID era, we retrospectively evaluate these proposed studies and offer a review of the techniques employed in AI diagnostic models, with a focus on the solutions proposed for different challenges. This review endeavors to provide insights into the diverse solutions designed to address the multifaceted challenges that arose during the pandemic. By doing so, we aim to prepare the AI community for the development of AI tools tailored to address public health emergencies effectively.

Cardiac magnetic resonance imaging (CMR) has emerged as a valuable diagnostic tool for cardiac diseases. However, a limitation of CMR is its slow imaging speed, which causes patient discomfort and introduces artifacts in the images. There has been growing interest in deep learning-based CMR imaging algorithms that can reconstruct high-quality images from highly under-sampled k-space data. However, the development of deep learning methods requires large training datasets, which have not been publicly available for CMR. To address this gap, we released a dataset that includes multi-contrast, multi-view, multi-slice and multi-coil CMR imaging data from 300 subjects. Imaging studies include cardiac cine and mapping sequences. Manual segmentations of the myocardium and chambers of all the subjects are also provided within the dataset. Scripts of state-of-the-art reconstruction algorithms were also provided as a point of reference. Our aim is to facilitate the advancement of state-of-the-art CMR image reconstruction by introducing standardized evaluation criteria and making the dataset freely accessible to the research community. Researchers can access the dataset at https://www.synapse.org/#!Synapse:syn51471091/wiki/., Comment: 14 pages, 8 figures

Diffusion tensor cardiac magnetic resonance (DT-CMR) is a method capable of providing non-invasive measurements of myocardial microstructure. Image registration is essential to correct image shifts due to intra and inter breath-hold motion and imperfect cardiac triggering. Registration is challenging in DT-CMR due to the low signal-to-noise and various contrasts induced by the diffusion encoding in the myocardium and surrounding organs. Traditional deformable registration corrects through-plane motion but at the risk of destroying the texture information while rigid registration inefficiently discards frames with local deformation. In this study, we explored the possibility of deep learning-based deformable registration on DT-CMR. Based on the noise suppression using low-rank features and diffusion encoding suppression using variational auto encoder-decoder, a B-spline based registration network extracted the displacement fields and maintained the texture features of DT-CMR. In this way, our method improved the efficiency of frame utilization, manual cropping, and computational speed., Comment: 7 pages, 4 figures, conference

Organoids are self-organized 3D cell clusters that closely mimic the architecture and function of in vivo tissues and organs. Quantification of organoid morphology helps in studying organ development, drug discovery, and toxicity assessment. Recent microscopy techniques provide a potent tool to acquire organoid morphology features, but manual image analysis remains a labor and time-intensive process. Thus, this paper proposes a comprehensive pipeline for microscopy analysis that leverages the SegmentAnything to precisely demarcate individual organoids. Additionally, we introduce a set of morphological properties, including perimeter, area, radius, non-smoothness, and non-circularity, allowing researchers to analyze the organoid structures quantitatively and automatically. To validate the effectiveness of our approach, we conducted tests on bright-field images of human induced pluripotent stem cells (iPSCs) derived neural-epithelial (NE) organoids. The results obtained from our automatic pipeline closely align with manual organoid detection and measurement, showcasing the capability of our proposed method in accelerating organoids morphology analysis., Comment: Replace Figure 4 with the correct version. The original version is wrong due to a column name mismatch

A core aim of neurocritical care is to prevent secondary brain injury. Spreading depolarizations (SDs) have been identified as an important independent cause of secondary brain injury. SDs are usually detected using invasive electrocorticography recorded at high sampling frequency. Recent pilot studies suggest a possible utility of scalp electrodes generated electroencephalogram (EEG) for non-invasive SD detection. However, noise and attenuation of EEG signals makes this detection task extremely challenging. Previous methods focus on detecting temporal power change of EEG over a fixed high-density map of scalp electrodes, which is not always clinically feasible. Having a specialized spectrogram as an input to the automatic SD detection model, this study is the first to transform SD identification problem from a detection task on a 1-D time-series wave to a task on a sequential 2-D rendered imaging. This study presented a novel ultra-light-weight multi-modal deep-learning network to fuse EEG spectrogram imaging and temporal power vectors to enhance SD identification accuracy over each single electrode, allowing flexible EEG map and paving the way for SD detection on ultra-low-density EEG with variable electrode positioning. Our proposed model has an ultra-fast processing speed (<0.3 sec). Compared to the conventional methods (2 hours), this is a huge advancement towards early SD detection and to facilitate instant brain injury prognosis. Seeing SDs with a new dimension - frequency on spectrograms, we demonstrated that such additional dimension could improve SD detection accuracy, providing preliminary evidence to support the hypothesis that SDs may show implicit features over the frequency profile.

Recent mainstream masked distillation methods function by reconstructing selectively masked areas of a student network from the feature map of its teacher counterpart. In these methods, the masked regions need to be properly selected, such that reconstructed features encode sufficient discrimination and representation capability like the teacher feature. However, previous masked distillation methods only focus on spatial masking, making the resulting masked areas biased towards spatial importance without encoding informative channel clues. In this study, we devise a Dual Masked Knowledge Distillation (DMKD) framework which can capture both spatially important and channel-wise informative clues for comprehensive masked feature reconstruction. More specifically, we employ dual attention mechanism for guiding the respective masking branches, leading to reconstructed feature encoding dual significance. Furthermore, fusing the reconstructed features is achieved by self-adjustable weighting strategy for effective feature distillation. Our experiments on object detection task demonstrate that the student networks achieve performance gains of 4.1% and 4.3% with the help of our method when RetinaNet and Cascade Mask R-CNN are respectively used as the teacher networks, while outperforming the other state-of-the-art distillation methods.

Temporal echocardiography image registration is a basis for clinical quantifications such as cardiac motion estimation, myocardial strain assessments, and stroke volume quantifications. In past studies, deep learning image registration (DLIR) has shown promising results and is consistently accurate and precise, requiring less computational time. We propose that a greater focus on the warped moving image's anatomic plausibility and image quality can support robust DLIR performance. Further, past implementations have focused on adult echocardiography, and there is an absence of DLIR implementations for fetal echocardiography. We propose a framework that combines three strategies for DLIR in both fetal and adult echo: (1) an anatomic shape-encoded loss to preserve physiological myocardial and left ventricular anatomical topologies in warped images; (2) a data-driven loss that is trained adversarially to preserve good image texture features in warped images; and (3) a multi-scale training scheme of a data-driven and anatomically constrained algorithm to improve accuracy. Our tests show that good anatomical topology and image textures are strongly linked to shape-encoded and data-driven adversarial losses. They improve different aspects of registration performance in a non-overlapping way, justifying their combination. Despite fundamental distinctions between adult and fetal echo images, we show that these strategies can provide excellent registration results in both adult and fetal echocardiography using the publicly available CAMUS adult echo dataset and our private multi-demographic fetal echo dataset. Our approach outperforms traditional non-DL gold standard registration approaches, including Optical Flow and Elastix. Registration improvements could be translated to more accurate and precise clinical quantification of cardiac ejection fraction, demonstrating a potential for translation., Comment: Our data-driven and anatomically constrained DLIR method's source code will be publicly available at https://github.com/kamruleee51/DdC-AC-DLIR

Scientific workflows bridge scientific challenges with computational resources. While dispel4py, a stream-based workflow system, offers mappings to parallel enactment engines like MPI or Multiprocessing, its optimization primarily focuses on dynamic process-to-task allocation for improved performance. An efficiency gap persists, particularly with the growing emphasis on conserving computing resources. Moreover, the existing dynamic optimization lacks support for stateful applications and grouping operations. To address these issues, our work introduces a novel hybrid approach for handling stateful operations and groupings within workflows, leveraging a new Redis mapping. We also propose an auto-scaling mechanism integrated into dispel4py's dynamic optimization. Our experiments showcase the effectiveness of auto-scaling optimization, achieving efficiency while upholding performance. In the best case, auto-scaling reduces dispel4py's runtime to 87% compared to the baseline, using only 76% of process resources. Importantly, our optimized stateful dispel4py demonstrates a remarkable speedup, utilizing just 32% of the runtime compared to the contender., Comment: 13 pages, 13 figures

Open international challenges are becoming the de facto standard for assessing computer vision and image analysis algorithms. In recent years, new methods have extended the reach of pulmonary airway segmentation that is closer to the limit of image resolution. Since EXACT'09 pulmonary airway segmentation, limited effort has been directed to quantitative comparison of newly emerged algorithms driven by the maturity of deep learning based approaches and clinical drive for resolving finer details of distal airways for early intervention of pulmonary diseases. Thus far, public annotated datasets are extremely limited, hindering the development of data-driven methods and detailed performance evaluation of new algorithms. To provide a benchmark for the medical imaging community, we organized the Multi-site, Multi-domain Airway Tree Modeling (ATM'22), which was held as an official challenge event during the MICCAI 2022 conference. ATM'22 provides large-scale CT scans with detailed pulmonary airway annotation, including 500 CT scans (300 for training, 50 for validation, and 150 for testing). The dataset was collected from different sites and it further included a portion of noisy COVID-19 CTs with ground-glass opacity and consolidation. Twenty-three teams participated in the entire phase of the challenge and the algorithms for the top ten teams are reviewed in this paper. Quantitative and qualitative results revealed that deep learning models embedded with the topological continuity enhancement achieved superior performance in general. ATM'22 challenge holds as an open-call design, the training data and the gold standard evaluation are available upon successful registration via its homepage., Comment: 32 pages, 16 figures. Homepage: https://atm22.grand-challenge.org/. Submitted

Robot-assisted surgery has made significant progress, with instrument segmentation being a critical factor in surgical intervention quality. It serves as the building block to facilitate surgical robot navigation and surgical education for the next generation of operating intelligence. Although existing methods have achieved accurate instrument segmentation results, they simultaneously generate segmentation masks for all instruments, without the capability to specify a target object and allow an interactive experience. This work explores a new task of Referring Surgical Video Instrument Segmentation (RSVIS), which aims to automatically identify and segment the corresponding surgical instruments based on the given language expression. To achieve this, we devise a novel Video-Instrument Synergistic Network (VIS-Net) to learn both video-level and instrument-level knowledge to boost performance, while previous work only used video-level information. Meanwhile, we design a Graph-based Relation-aware Module (GRM) to model the correlation between multi-modal information (i.e., textual description and video frame) to facilitate the extraction of instrument-level information. We are also the first to produce two RSVIS datasets to promote related research. Our method is verified on these datasets, and experimental results exhibit that the VIS-Net can significantly outperform existing state-of-the-art referring segmentation methods. Our code and our datasets will be released upon the publication of this work.