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1,026 results on '"Yang, Ju Dong"'

201. Efficacy and Safety of Transarterial Radioembolization Versus Chemoembolization in Patients With Hepatocellular Carcinoma

Author

Moreno-Luna, Laura E., Yang, Ju Dong, Sanchez, William, Paz-Fumagalli, Ricardo, Harnois, Denise M., Mettler, Teresa A., Gansen, Denise N., de Groen, Piet C., Lazaridis, Konstantinos N., Narayanan Menon, K. V., LaRusso, Nicholas F., Alberts, Steven R., Gores, Gregory J., Fleming, Chad J., Slettedahl, Seth W., Harmsen, William S., Therneau, Terry M., Wiseman, Gregory A., Andrews, James C., and Roberts, Lewis R.

Published
2013
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202. Abstract 764: Circulating tumor cell-based mRNA scoring system for prognostication of hepatocellular carcinoma - Translating HCC tissue-based mRNA profiling into a non-invasive setting

Author

Lee, Yi-Te, primary, Sun, Na, additional, Kim, Minhyung, additional, Wang, Jasmine J., additional, Tran, Benjamin V., additional, Zhang, Ryan Y., additional, Zhang, Ceng, additional, Sadeghi, Saeed, additional, Finn, Richard S., additional, Saab, Sammy, additional, Busuttil, Ronald W., additional, Zhu, Yazhen, additional, Tseng, Hsian-Rong, additional, You, Sungyong, additional, Yang, Ju Dong, additional, and Agopian, Vatche G., additional

Published
2021
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206. A morphological subset of circulating tumor cells in advanced prostate cancer reveals a potential biomarker for clinical outcomes.

Author

Wang, Jasmine Jiemei, primary, Cavassani, Karen Angelica, additional, Teng, Pai-Chi, additional, Chen, Jie-Fu, additional, Jan, Yu Jen, additional, Chu, Gina Chia-Yi, additional, Lee, Yi-Te, additional, Gao, Allen, additional, Di Vizio, Dolores, additional, Chung, Leland WK, additional, You, Sungyong, additional, Zhu, Yazhen, additional, Freeman, Michael, additional, Rogatko, Andre, additional, Yang, Ju Dong, additional, Tseng, Hsian-Rong, additional, and Posadas, Edwin Melencio, additional

Published
2021
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208. DNA Methylation Markers for Detection of Cholangiocarcinoma: Discovery, Validation, and Clinical Testing in Biliary Brushings and Plasma

Author

Yang, Ju Dong, primary, Ghoz, Hassan, additional, Aboelsoud, Mohammed M., additional, Taylor, William R., additional, Yab, Tracy C., additional, Berger, Calise K., additional, Cao, Xiaoming, additional, Foote, Patrick H., additional, Giama, Nasra H., additional, Barr Fritcher, Emily G., additional, Mahoney, Douglas W., additional, Moser, Catherine D., additional, Smyrk, Thomas C., additional, Kipp, Benjamin R., additional, Gores, Gregory J., additional, Roberts, Lewis R., additional, and Kisiel, John B., additional

Published
2021
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209. High Neutrophil–Lymphocyte Ratio and Delta Neutrophil–Lymphocyte Ratio Are Associated with Increased Mortality in Patients with Hepatocellular Cancer

Author

Rich, Nicole E., primary, Parvathaneni, Aarthi, additional, Sen, Ahana, additional, Odewole, Mobolaji, additional, Arroyo, Ana, additional, Mufti, Arjmand R., additional, Kerr, Thomas A., additional, Grant, Lafaine, additional, Tujios, Shannan R., additional, Mayo, Marlyn J., additional, Lee, William M., additional, Yang, Ju Dong, additional, Yokoo, Takeshi, additional, Gopal, Purva, additional, Hoshida, Yujin, additional, Zhu, Hao, additional, Yopp, Adam C., additional, Marrero, Jorge A., additional, and Singal, Amit G., additional

Published
2021
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210. 433 THE ASSOCIATION OF SUSTAINED VIROLOGIC RESPONSE ON TREATMENT OUTCOMES IN PATIENTS WITH HEPATOCELLULAR CARCINOMA WITH HEPATITIS C

Author

Parikh, Neehar D., primary, Mehta, Neil, additional, Hoteit, Maarouf, additional, Yang, Ju Dong, additional, John, Binu V., additional, Moon, Andrew M., additional, Salgia, Reena, additional, Pillai, Anjana A., additional, Kassab, Ihab, additional, Saeed, Naba, additional, Thyssen, Emil, additional, Nithani, Piyush, additional, Mckinney, Jeffrey, additional, Chan, Wesley, additional, Durkin, Claire, additional, Connor, Matthew, additional, Alsudaney, Manaf, additional, Durand, Brenda, additional, Nissen, Nicholas N., additional, Kim, Hannah P., additional, Paknikar, Raghavendra, additional, Rich, Nicole E., additional, Schipper, Matthew, additional, and Singal, Amit G., additional

Published
2021
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211. Fr388 THERAPEUTIC UNDERUTILIZATION AND DELAY IN HEPATOCELLULAR CARCINOMA: TRENDS, ASSOCIATED FACTORS AND THEIR CLINICAL IMPACT FROM NATIONAL CANCER DATABASE ANALYSIS

Author

Govalan, Rajalakshmi, primary, Luu, Michael, additional, Lauzon, Marie, additional, Kosari, Kambiz, additional, Ahn, Joseph C., additional, Rich, Nicole E., additional, Lu, Shelly C., additional, Nissen, Nicholas N., additional, Roberts, Lewis R., additional, Singal, Amit G., additional, and Yang, Ju Dong, additional

Published
2021
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212. Fr390 COMPARISON OF SURGICAL RESECTION AND SYSTEMIC TREATMENT FOR HEPATOCELLULAR CARCINOMA WITH VASCULAR INVASION: NATIONAL CANCER DATABASE ANALYSIS

Author

Govalan, Rajalakshmi, primary, Lauzon, Marie, additional, Luu, Michael, additional, Ahn, Joseph C., additional, Kosari, Kambiz, additional, Todo, Tsuyoshi, additional, Kim, Irene, additional, Noureddin, Mazen, additional, Kuo, Alexander, additional, Ayoub, Walid S., additional, Vinay, Sundaram, additional, Lu, Shelly C., additional, Roberts, Lewis R., additional, Singal, Amit G., additional, Heimbach, Julie, additional, Agopian, Vatche, additional, Nissen, Nicholas N., additional, and Yang, Ju Dong, additional

Published
2021
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213. Current impact of viral hepatitis on liver cancer development:The challenge remains

Author

de Mattos, Ângelo Zambam, Debes, Jose D., Boonstra, Andre, Yang, Ju Dong, Balderramo, Domingo C., Sartori, Giovana D.P., de Mattos, Angelo Alves, de Mattos, Ângelo Zambam, Debes, Jose D., Boonstra, Andre, Yang, Ju Dong, Balderramo, Domingo C., Sartori, Giovana D.P., and de Mattos, Angelo Alves

Abstract

Chronic infections due to hepatitis B and hepatitis C viruses are responsible for most cases of hepatocellular carcinoma (HCC) worldwide, and this association is likely to remain during the next decade. Moreover, viral hepatitis-related HCC imposes an important burden on public health in terms of disability-adjusted life years. In order to reduce such a burden, some major challenges must be faced. Universal vaccination against hepatitis B virus, especially in the neonatal period, is probably the most relevant primary preventive measure against the development of HCC. Moreover, considering the large adult population already infected with hepatitis B and C viruses, it is also imperative to identify these individuals to ensure their access to treatment. Both hepatitis B and C currently have highly effective therapies, which are able to diminish the risk of development of liver cancer. Finally, it is essential for individuals at high-risk of HCC to be included in surveillance programs, so that tumors are detected at an early stage. Patients with hepatitis B or C and advanced liver fibrosis or cirrhosis benefit from being followed in a surveillance program. As hepatitis B virus is oncogenic and capable of leading to liver cancer even in individuals with early stages of liver fibrosis, other high-risk groups of patients with hepatitis B are also candidates for surveillance. Considerable effort is required concerning these strategies in order to decrease the incidence and the mortality of viral hepatitis-related HCC.

Published
2021

216. Transarterial Radioembolization Versus Systemic Treatment for Hepatocellular Carcinoma with Macrovascular Invasion: Analysis of the U.S. National Cancer Database

Author

Ahn, Joseph C., primary, Lauzon, Marie, additional, Luu, Michael, additional, Friedman, Marc L., additional, Kosari, Kambiz, additional, Nissen, Nicholas, additional, Lu, Shelly C., additional, Roberts, Lewis R., additional, Singal, Amit G., additional, and Yang, Ju Dong, additional

Published
2021
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217. Differential characteristics and outcomes of Asian and non‐Asian patients with HBV‐related hepatocellular carcinoma

Author

Huang, Daniel Q., primary, Hoang, Joseph K., additional, Leong, Jennifer, additional, Riveiro‐Barciela, Mar, additional, Maeda, Mayumi, additional, Yang, Ju Dong, additional, Accarino, Elena Vargas, additional, Thin, Khin, additional, Trinh, Lindsey, additional, Cheung, Ramsey C., additional, Roberts, Lewis R., additional, Buti, Maria, additional, Schwartz, Myron, additional, and Nguyen, Mindie H., additional

Published
2021
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218. Blood Salvage and Autotransfusion With Single Leukoreduction Does Not Increase the Risk of Tumor Recurrence After Liver Transplantation for Advanced Hepatocellular Carcinoma

Author

Kwon, Ji-Hye, primary, Han, Sangbin, additional, Kim, Doyeon, additional, Kuk, Joon Hee, additional, Cho, Hyun, additional, Kim, Seonwoo, additional, Yang, Ju Dong, additional, Kim, Chul, additional, Kim, Jong Man, additional, Choi, Gyu Sung, additional, Joh, Jae-Won, additional, Ko, Justin S., additional, Gwak, Mi Sook, additional, and Kim, Gaabsoo, additional

Published
2021
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219. Nuclear size of circulating tumor cells in advanced prostate cancer to reveal a potential biomarker for clinical outcomes and androgen receptor indifference.

Author

Wang, Jasmine Jiemei, primary, Cavassani, Karen Angelica, additional, Teng, Pai-Chi, additional, Chen, Jie-Fu, additional, Jan, Yu Jen, additional, Chu, Gina Chia-Yi, additional, Lee, Yi-Te, additional, Gao, Allen, additional, Di Vizio, Dolores, additional, Chung, Leland WK, additional, You, Sungyong, additional, Zhu, Yazhen, additional, Freeman, Michael, additional, Rogatko, Andre, additional, Yang, Ju Dong, additional, Tseng, Hsian-Rong, additional, and Posadas, Edwin Melencio, additional

Published
2021
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221. TOP-065 - Multidimensional genomic analysis of cell-free DNA for early detection of hepatocellular carcinoma

Author

Yang, Ju Dong, Liu, Poching, Alsudaney, Manaf, Kim, Naomy, Hernandez, Perla, Marquez, Monserrat, Torres, Patricia, Trivedi, Hirsch, Ayoub, Walid S, Kuo, Alexander, Friedman, Marc, Steinberger, Jonathan, Lipshutz, H. Gabriel, Gong, Jun, Osipov, Arsen, Hendifar, Andrew, Sankar, Kamya, Todo, Tsuyoshi, Kim, Irene, Voidonikolas, Georgios, Brennan, Todd, Wisel, Steven, Steggerda, Justin, Ulyanov, Anatoly, Guo, Jason, Randall, Jonathan, Ahmad, Moin, Lu, Kang, Song, Qianqian, Wang, Pei, Wang, Yayun, Li, Mengfan, Cao, Dandan, Ma, Chenyu, Shi, Zongkui, Kosari, Kambiz, Nissen, Nicholas, and Yan, Hai

Published
2023
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229. Evaluation and management of liver masses

Author

Roberts, Lewis R., editor, Yang, Ju Dong, editor, Venkatesh, Sudhakar K., editor, Roberts, Lewis R., editor, Yang, Ju Dong, editor, and Venkatesh, Sudhakar K., editor

Published
2020

230. Increase in Alcoholic Hepatitis as an Etiology for Liver Transplantation in the United States: A 2004-2018 Analysis.

Author

Noureddin, Nabil, Noureddin, Nabil, Yang, Ju Dong, Alkhouri, Naim, Noreen, Samantha M, Toll, Alice E, Todo, Tsuyoshi, Ayoub, Walid, Kuo, Alexander, Voidonikolas, Georgios, Kotler, Honore G, Pelphrey, Michalyn D, Durand, Brenda J, Kosari, Kambiz, Brennan, Todd V, Kim, Irene, Klein, Andrew S, Seki, Ekihiro, Nissen, Nicholas N, Lu, Shelly C, Sundaram, Vinay, Noureddin, Mazen, Noureddin, Nabil, Noureddin, Nabil, Yang, Ju Dong, Alkhouri, Naim, Noreen, Samantha M, Toll, Alice E, Todo, Tsuyoshi, Ayoub, Walid, Kuo, Alexander, Voidonikolas, Georgios, Kotler, Honore G, Pelphrey, Michalyn D, Durand, Brenda J, Kosari, Kambiz, Brennan, Todd V, Kim, Irene, Klein, Andrew S, Seki, Ekihiro, Nissen, Nicholas N, Lu, Shelly C, Sundaram, Vinay, and Noureddin, Mazen

Abstract

BackgroundChanging opinions on the alcohol abstinence requirement have led to increased liver transplantation (LT) for alcoholic hepatitis (AH). We aimed to determine the trend in LT for AH in the United States and overall and graft survival rates.MethodsAdult liver-alone and liver-kidney registrations added to the Organ Procurement and Transplantation Network waiting list between 2004 and 2018 were divided into 3 periods (2004-2009, 2010-2013, 2014-2018). Kaplan-Meier survival models illustrated patient and graft survival.ResultsBetween 2004 and 2018, 529 AH patients were registered for and 254 received LT. By periods, 116, 73, and 340 patients were registered for and 49, 17, and 188 patients received LT, respectively, indicating a increase in LT for AH from 2014 to 2018. Yearly registrants from 2014 to 2018 were 32, 47, 51, 70, and 140, and recipients were 16, 24, 24, 38, and 88, respectively, indicating increases of 338% and 450% in registrants and recipients, respectively, since 2014. AH patients had the highest 1- and 3-year posttransplant survival (93.2% and 87.3%, respectively) and graft survival (90.4% and 84.8%, respectively) comparing to other LT recipients.ConclusionsLT for AH in the United States is at an all-time high with an increased overall patient and graft survival.

Published
2020

231. Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring.

Author

Sun, Na, Sun, Na, Lee, Yi-Te, Zhang, Ryan Y, Kao, Rueihung, Teng, Pai-Chi, Yang, Yingying, Yang, Peng, Wang, Jasmine J, Smalley, Matthew, Chen, Pin-Jung, Kim, Minhyung, Chou, Shih-Jie, Bao, Lirong, Wang, Jing, Zhang, Xinyue, Qi, Dongping, Palomique, Juvelyn, Nissen, Nicolas, Han, Steven-Huy B, Sadeghi, Saeed, Finn, Richard S, Saab, Sammy, Busuttil, Ronald W, Markovic, Daniela, Elashoff, David, Yu, Hsiao-Hua, Li, Huiying, Heaney, Anthony P, Posadas, Edwin, You, Sungyong, Yang, Ju Dong, Pei, Renjun, Agopian, Vatche G, Tseng, Hsian-Rong, Zhu, Yazhen, Sun, Na, Sun, Na, Lee, Yi-Te, Zhang, Ryan Y, Kao, Rueihung, Teng, Pai-Chi, Yang, Yingying, Yang, Peng, Wang, Jasmine J, Smalley, Matthew, Chen, Pin-Jung, Kim, Minhyung, Chou, Shih-Jie, Bao, Lirong, Wang, Jing, Zhang, Xinyue, Qi, Dongping, Palomique, Juvelyn, Nissen, Nicolas, Han, Steven-Huy B, Sadeghi, Saeed, Finn, Richard S, Saab, Sammy, Busuttil, Ronald W, Markovic, Daniela, Elashoff, David, Yu, Hsiao-Hua, Li, Huiying, Heaney, Anthony P, Posadas, Edwin, You, Sungyong, Yang, Ju Dong, Pei, Renjun, Agopian, Vatche G, Tseng, Hsian-Rong, and Zhu, Yazhen

Abstract

We report a covalent chemistry-based hepatocellular carcinoma (HCC)-specific extracellular vesicle (EV) purification system for early detection of HCC by performing digital scoring on the purified EVs. Earlier detection of HCC creates more opportunities for curative therapeutic interventions. EVs are present in circulation at relatively early stages of disease, providing potential opportunities for HCC early detection. We develop an HCC EV purification system (i.e., EV Click Chips) by synergistically integrating covalent chemistry-mediated EV capture/release, multimarker antibody cocktails, nanostructured substrates, and microfluidic chaotic mixers. We then explore the translational potential of EV Click Chips using 158 plasma samples of HCC patients and control cohorts. The purified HCC EVs are subjected to reverse-transcription droplet digital PCR for quantification of 10 HCC-specific mRNA markers and computation of digital scoring. The HCC EV-derived molecular signatures exhibit great potential for noninvasive early detection of HCC from at-risk cirrhotic patients with an area under receiver operator characteristic curve of 0.93 (95% CI, 0.86 to 1.00; sensitivity = 94.4%, specificity = 88.5%).

Published
2020

235. Comparison of Surgical Resection and Systemic Treatment for Hepatocellular Carcinoma with Vascular Invasion: National Cancer Database Analysis

Author

Govalan, Rajalakshmi, primary, Lauzon, Marie, additional, Luu, Michael, additional, Ahn, Joseph C., additional, Kosari, Kambiz, additional, Todo, Tsuyoshi, additional, Kim, Irene K., additional, Noureddin, Mazen, additional, Kuo, Alexander, additional, Walid, Ayoub S., additional, Sundaram, Vinay, additional, Lu, Shelly C., additional, Roberts, Lewis R., additional, Singal, Amit G., additional, Heimbach, Julie K., additional, Agopian, Vatche G., additional, Nissen, Nicholas, additional, and Yang, Ju Dong, additional

Published
2021
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236. Direct-Acting Antiviral Therapy in Liver Transplant Patients With Hepatocellular Carcinoma and Hepatitis C

Author

Tse, Chung Sang, primary, Yang, Ju Dong, additional, Mousa, Omar Y., additional, Nelson, Kevin M., additional, Pungpapong, Surakit, additional, Keaveny, Andrew, additional, Aqel, Bashar A., additional, Vargas, Hugo, additional, Dickson, Rolland C., additional, Watt, Kymberly, additional, Gores, Gregory J., additional, Roberts, Lewis R., additional, and Leise, Michael D., additional

Published
2020
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239. Circulating Tumor Cell–Based Messenger RNA Scoring System for Prognostication of Hepatocellular Carcinoma: Translating Tissue‐Based Messenger RNA Profiling Into a Noninvasive Setting.

Author

Lee, Yi‐Te, Sun, Na, Kim, Minhyung, Wang, Jasmine J., Tran, Benjamin V., Zhang, Ryan Y., Qi, Dongping, Zhang, Ceng, Chen, Pin‐Jung, Sadeghi, Saeed, Finn, Richard S., Saab, Sammy, Han, Steven‐Huy B., Busuttil, Ronald W., Pei, Renjun, Zhu, Yazhen, Tseng, Hsian‐Rong, You, Sungyong, Yang, Ju Dong, and Agopian, Vatche G.

Published
2022
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247. Increase in Alcoholic Hepatitis as an Etiology for Liver Transplantation in the United States: A 2004–2018 Analysis

Author

Noureddin, Nabil, primary, Yang, Ju Dong, additional, Alkhouri, Naim, additional, Noreen, Samantha M., additional, Toll, Alice E., additional, Todo, Tsuyoshi, additional, Ayoub, Walid, additional, Kuo, Alexander, additional, Voidonikolas, Georgios, additional, Kotler, Honore G., additional, Pelphrey, Michalyn D., additional, Durand, Brenda J., additional, Kosari, Kambiz, additional, Brennan, Todd V., additional, Kim, Irene, additional, Klein, Andrew S., additional, Seki, Ekihiro, additional, Nissen, Nicholas N., additional, Lu, Shelly C., additional, Sundaram, Vinay, additional, and Noureddin, Mazen, additional

Published
2020
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248. Effects of Cirrhosis and Diagnosis Scenario in Metabolic‐Associated Fatty Liver Disease‐Related Hepatocellular Carcinoma

Author

Chen, Vincent L., primary, Yeh, Ming‐Lun, additional, Yang, Ju Dong, additional, Leong, Jennifer, additional, Huang, Daniel Q., additional, Toyoda, Hidenori, additional, Chen, Yao‐Li, additional, Guy, Jennifer, additional, Maeda, Mayumi, additional, Tsai, Pei‐Chien, additional, Huang, Chung‐Feng, additional, Yasuda, Satoshi, additional, Le, An K., additional, Dang, Hansen, additional, Giama, Nasra H., additional, Ali, Hamdi A., additional, Zhang, Ning, additional, Wang, Xiaozhong, additional, Jun, Dae Won, additional, Tseng, Cheng‐Hao, additional, Hsu, Yao‐Chun, additional, Huang, Jee‐Fu, additional, Dai, Chia‐Yen, additional, Chuang, Wan‐Long, additional, Zhu, Qiang, additional, Dan, Yock Young, additional, Schwartz, Myron, additional, Roberts, Lewis R., additional, Yu, Ming‐Lung, additional, and Nguyen, Mindie H., additional

Published
2020
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250. Purification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring

Author

Sun, Na, primary, Lee, Yi-Te, additional, Zhang, Ryan Y., additional, Kao, Rueihung, additional, Teng, Pai-Chi, additional, Yang, Yingying, additional, Yang, Peng, additional, Wang, Jasmine J., additional, Smalley, Matthew, additional, Chen, Pin-Jung, additional, Kim, Minhyung, additional, Chou, Shih-Jie, additional, Bao, Lirong, additional, Wang, Jing, additional, Zhang, Xinyue, additional, Qi, Dongping, additional, Palomique, Juvelyn, additional, Nissen, Nicolas, additional, Han, Steven-Huy B., additional, Sadeghi, Saeed, additional, Finn, Richard S., additional, Saab, Sammy, additional, Busuttil, Ronald W., additional, Markovic, Daniela, additional, Elashoff, David, additional, Yu, Hsiao-hua, additional, Li, Huiying, additional, Heaney, Anthony P., additional, Posadas, Edwin, additional, You, Sungyong, additional, Yang, Ju Dong, additional, Pei, Renjun, additional, Agopian, Vatche G., additional, Tseng, Hsian-Rong, additional, and Zhu, Yazhen, additional

Published
2020
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