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T2relaxation decay curves from in vivo human brain tissue are rarely mono‐exponential. Partial volume averaging further reduces the chance of mono‐exponential decay. Moreover, the parameters derived from few‐echo mono‐exponential fits change with the measurement echo times and have the largest possible variance. In this note, multi‐exponential fits to 32‐echo relaxation decay curves from in vivo human brain are used to design simulations (where the truth is known) to demonstrate the pitfalls of few‐echo mono‐exponential interpretations. Magn Reson Med 41:1255–1257, 1999. © 1999 Wiley‐Liss, Inc.

T2 relaxation decay curves from in vivo human brain tissue are rarely mono-exponential. Partial volume averaging further reduces the chance of mono-exponential decay. Moreover, the parameters derived from few-echo mono-exponential fits change with the measurement echo times and have the largest possible variance. In this note, multi-exponential fits to 32-echo relaxation decay curves from in vivo human brain are used to design simulations (where the truth is known) to demonstrate the pitfalls of few-echo mono-exponential interpretations. Magn Reson Med 41:1255–1257, 1999. © 1999 Wiley-Liss, Inc.

Subjects with diabetes who attended rural surveys in Western Australia from 1978 to 1982 were followed up to ascertain death rates and the causes of death recorded on death certificates. Cardiovascular disease was assigned as the direct cause of death in 63% of deaths, with equal rates in male and female subjects, and renal disease in 8% of deaths with the proportion in women (12%) being greater than that in men (4%). The diagnosis of diabetes was stated on only 65% of the death certificates, and in only 24% was diabetes recorded as a direct or antecedent cause. In the same cohort the Australian Bureau of Statistics coded diabetes as the underlying cause of death in 24%, while attributing deaths to cardiovascular disease in 50% of the cases. This study suggests that diabetes is considerably under‐reported both on doctors' death certificates and in the mortality figures of the Australian Bureau of Statistics.

Die bisher höchsten kubischen NLO‐Aktivitäten(NLO = nichtlinear optisch) monomerer metallorganischer Komplexe in Lösung zeigt eine Reihe von Alkinyl(triphenylphosphan)gold‐Komplexen (schematische Darstellung rechts). In Studien zur Struktur/Wirkungs‐Beziehung wurde der Einfluß von Strukturänderungen im Chromophor auf die NLO‐Antwort untersucht.

A shift in the Western diet since the industrial revolution has resulted in a dramatic increase in the consumption of omega-6 fatty acids, with a concurrent decrease in the consumption of omega-3 fatty acids. This decrease in omega-3 fatty acid consumption has been associated with significant disease burden, including increased susceptibility to infectious diseases. Here we provide evidence that DHA, an omega-3 fatty acid, has superior antimicrobial effects upon the highly drug-resistant pathogen Acinetobacter baumannii, thereby providing insights into one of the potential health benefits of omega-3 fatty acids. The identification and characterization of two novel bacterial membrane protective mechanisms against host fatty acids provide important insights into A. baumanniiadaptation during disease. Furthermore, we describe a novel role for the major multidrug efflux system AdeIJK in A. baumanniimembrane maintenance and lipid transport. This core function, beyond drug efflux, increases the appeal of AdeIJK as a therapeutic target.

Discusses the factors that must be considered in creating culturally responsive school-age child care programs. Organization of a team of teachers, administrators, parents and the community to develop a vision for such programs; Incorporation of the personal philosophies of members of the team into a larger program philosophy; Brainstorming strategies which include the right of everyone to speak about issues related to the program.

The article offers information on the Manifesto Series guidebook of the company Rocky Mountain Books (RMB). It informs that the guidebook is a series of small attractive hardcover books which constitutes social or scientific issues in a populist vein. It tells that the series has been sold enough to justify increasing RMB's commitment from three to five titles per year. It further informs that the company has also redesigned its colophon and has launched a revamped website.

The article focuses on writers' residencies and retreats. It states that authors need time and seclusion for creative writing and the trend of writer's residencies and retreats is increasing. It is stated that writers-in-residence programs provide full-time salary, while at writers' retreats authors bear their expenses. In library residencies authors have to follow office hours and are allowed to spend rest of the time working from their home.

The article offers information on a discussion hosted by the Book and Periodical Council of Canada in November 2010. Titled as "Our Cultural Borders: Barrier or Bounty," it was organized to analyze the advantages and disadvantages of foreign ownership restrictions in the Canadian publishing industry. Under the existing "Revised Foreign Investment Policy in Book Publishing and Distribution," which took effect in 1992, foreign investments should be compatible with cultural policies of Canada.

The article reports on author Alexander MacLeod, his debut short story collection and his next book. It reports that MacLeod's new book "Light Lifting," is an exception to his other books which are never reviewed and shortlisted for any major literary awards. MacLeod, who is the son of author Alistair MacLeod, never used his family name to gain publicity. It reports that MacLeod now teaches at Saint Mary's University, San Antonio in Texas and has no plans to pursue a full time literary career.

The article presents information on dollars 11 million perpetual access licence to thousands of canadian e-books purchased by Canadian Research Knowledge Network (CRKN) of Canada. It states that 47 academic publishers involved McGill-Queens University Press, University of Toronto press Inc. and Wilfrid Laurier University Press. McGill-Queens University Press business manager Esther Oziel acknowledges that the deal brought revenue of about 30 percent annual earnings.

The article discusses sexual harassment of women executives in the publishing industry. It informs that the lawsuits filed against Penguin Canada for wrongful dismissal and its president David Davidar for sexual harassment have had an out of court settlement. It resulted in termination of Davidar and hiring of the claimant Lisa Rundle as rights and contracts director. It focuses on issue of gender imbalance and sexual harassment and states that women are never given higher executive positions.

The article reports on the plan of Penguin Canada to launch another classical imprint called Allen Lane, which will be the non-fiction counterpart to Hamish Hamilton Canada. According to Diane Turbide, publishing director of Penguin Canada, the primary focus of their plan is not the average shopper but the booksellers. It notes that the new imprints will have a buy in title by Henry Kissinger regarding China and Charles Taylor Prize-winning historian Tim Cook's "The Madman and the Butcher."

The article focuses on the future of indigenous publishers and booksellers as the U.S.-based Amazon, the country's largest online retailer, aimed on establishing a market in Canada. It notes that the Department of Canadian Heritage still do not have the decision whether to allow the retail or not. However, Amazon vice president of global public policy Paul Misener is confident enough that their application will be granted.

The article reports that while most of the U.S. publishers have already entered into the electronic book (e-book) market the Canadian publishers have been slower to get into the field. The Association of Canadian Publishers has been solving this problem by helping Canadian firms digitize their lists. Besides this many Canadian publishers have hired new staff or expanded job descriptions. The Anansi launched its first commercial e-books with Kobo in December 2009.

The article offers information on Susan Juby's memoir, "Nice Recovery" which is stated to be based on her addiction to alcohol in her teenage years. As stated, Nice Recovery records her journey from being an addict to successfully kicking the habit and becoming sober. Reportedly, the idea of compiling a memoir was inspired by her conversation with her readers who were keen to know about her personal life.

The article offers information on the nature of younger generation of authors to work for a living in Canada. Toronto-based author Sheila Heti, states that scrambling to make a living is not new in the writing biz. Agent Denise Bukowski states that advances have been shrinking due to the arrival of the BookNet Canada SalesDate in 2005. Author Saleema Nawaz states that she is nearing the end of her novels, but she is not sure of what the future holds with her savings.

The article focuses on the policy for restricting access to the Library and Archives Canada (LAC) Cataloguing in Publication data (CIP). Traditionally, CIP data has been provided free of charge to all published works. As reported, the rules for CIP have been altered so that titles with print runs of less than 100 copies can no longer access CIP data at all. As a result, small-run titles will be catalogued only after a published copy has been submitted for legal deposit.

Presents the poem "Precordial Thump," by Zoe Whittall. First Line: red rimmed reading glasses, fern green flats; Last Line: This is my birth name. This is real.

The article presents the views of the author on being a writer. She refers to her previous jobs in the publishing industry from working as a receptionist, bookseller, freelance editor to columnist, publicist and finally as an author. The author believes that writers get to interact with people all day long. She says that a writer expects his publishers to work as hard as he himself does to compile his book.

BRIAN FERNEYHOUGH: Shadowtime. Nicolas Hodges (pno, speaker), Mats Scheidegger (gtr), Neue Vocalsolisten Stuttgart, Nieuw Ensemble, c. Jurjen Hempel. NMC D123 (2-CD set).

MURAIL: Complete Piano Works. Marilyn Nonken (pno). Metier MSV CD92097 (2-CD set).

Presents letters to the editor on topics related to boating. Inquiry of the sender on the method of mould prevention; Narration of the sender on the qualifications of a good racing sailors; "Harry Highet in Vintage," which discussed about boatbuilder Harry Highet.

LACHENMANN: Piano Music. Marino Formenti (pno). collegno WWE 1CD 20222.

NEUWIRTH: Bählamms Fest. Klangforum Wien, c. Johannes Kalitske. Kairos 00 123 42KAI (2-disc set).

WEIR: Piano Concerto, Distance and Enchantment, and other works. William Howard (pno), Susan Tomes (pno), The Schubert Ensemble, Domus. NMC DO90 (2-CD set).

YUN: My Land, My People!; Exemplum in Memoriam Kwangju. Chorus and State Symphony Orchestra of the Democratic Peoples Republic of Korea, c. Byung-Hwa Kim. Symphonies Nos. 1–5. Filharmonia Pomorska Bydgoszcz, c. Takao Ukigaya. Richard Salter (bar). CPO 999 165-2 (4-CD set)

The largest cubic nonlinear optical activitiesthus far determined for monomeric organometallic complexes in solution (schematic representation on the right) have been found for alkynyl(triphenylphosphane)gold complexes. In structure–property studies the influence of structural changes in the chromophore on the nonlinear response was systematically investigated.

Focuses on the future of David and Marilyn Handley's dairy business in Great Britain. Impact of the lack of affordable milk quotas on the business; Building and equipment investments; Farm accounts; Summit meetings; Efforts to consolidate the dairy business.