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1,240 results on '"Wang, Haiyun"'

211. Transcutaneous Electrical Acupoint Stimulation Decreases the Incidence of Postoperative Nausea and Vomiting After Laparoscopic Non-gastrointestinal Surgery: A Multi-Center Randomized Controlled Trial

Author

Gao, Wei, primary, Zhang, Linzhong, additional, Han, Xuechang, additional, Wei, Lai, additional, Fang, Jie, additional, Zhang, Xiaqing, additional, Zhang, Jiaqiang, additional, Wang, Haiyun, additional, Zhou, Qi, additional, Wang, Chenggang, additional, Chen, Wenting, additional, Ni, Xinli, additional, Yang, Lan, additional, Du, Ruini, additional, Wang, Ge, additional, Liu, Bingyu, additional, Li, Yajuan, additional, Zhang, Shanshan, additional, and Wang, Qiang, additional

Published
2022
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216. Aluminum composites based on high-strength alloy B95 treated with activated dispersed particles

Author

Wang, Yangwei and Wang, Haiyun

Abstract

В работе представлены результаты исследований по получению композитов при обработке алюминиевого расплава на основе высокопрочного сплава В95 активированными дисперсными частицами нитридов (AlN, Si3N4, TiN), карбидов (SiC, TiC), наноструктурированного углерода (фуллереновой сажи), азотсодержащими компонентами (глицин C2H5NO2, карбамид CH4N2O). Приведена оценка прочностных свойств получаемых композитов от режимов активации шихты с дисперсными частицами и режимов термообработки материала. Показана возможность повышения прочностных характеристик литейного композита на 15–20 % за счет дополнительной механоактивации шихты и достижения после термической обработки предела прочности при сжатии 900–1050 МПа, твердости 150–160 НВ, модуля упругости 20–25 ГПа.

Published
2022

217. Drug–Drug Interactions Of Amiodarone And Quinidine On The Pharmacokinetics Of Eliglustat In Rats

Author

Wang, Qiong, Wang, Haiyun, Zhong, Youyan, and Zhang, Qiang

Subjects
Male, Pyrrolidines, Dose-Response Relationship, Drug, Molecular Structure, eliglustat, Amiodarone, Quinidine, Rats, Rats, Sprague-Dawley, Structure-Activity Relationship, UPLC-MS/MS, Tandem Mass Spectrometry, Animals, Drug Interactions, drug–drug interaction, Chromatography, High Pressure Liquid, Original Research
Abstract

Background Eliglustat, a new oral substrate-reduction therapy, was recently approved as a first-line therapy for Gaucher's disease type 1 (GD1) patients. Purpose The purpose of the present study was to develop and validate a simple UPLC-MS/MS method for the measurement of plasma-eliglustat concentration and to investigate the effects of amiodarone and quinidine on eliglustat metabolism in rats. Methods Eighteen rats were randomly divided into three groups (n=6): control (0.5% CMC-Na, group A), amiodarone (60 mg/kg, group B), and quinidine (100 mg/kg, group C). Thirty minutes later, 10 mg/kg eliglustat was orally administered to each rat and concentrations of eliglustat in the rats determined by our UPLC-MS/MS method. Results Amiodarone and quinidine increased the main pharmacokinetic parameters (AUC0→t, AUC0→∞, and Cmax) of eliglustat significantly and decreased clearance obviously. Conclusion Amiodarone and quinidine can elevate eliglustat exposure and have an inhibitory effect on eliglustat metabolism. Clearly, appropriate pharmacological studies of eliglustat in patients treated with amiodarone or quinidine should be done in future.

Published
2019

218. A first principles study of a spin-polarized two-dimensional polar metal at the SrVO3/PbTiO3 heterostructure interface.

Author

Shen, Menglan, Weng, Yakui, Yi, Yingwei, Geng, Qingfeng, Yan, Wei, Wang, Haiyun, Yang, Jianping, and Li, Xing'ao

Subjects
HETEROJUNCTIONS, ELECTRONIC structure, ATOMIC structure, DENSITY functional theory, SUPERLATTICES, CHARGE transfer, TRANSITION metals
Abstract

The electronic structure, magnetic properties, and atomic structure of SrVO 3 / PbTiO 3 superlattices along different crystallographic orientations are investigated using density functional theory. It is revealed that Ti ions in the PbTiO 3 layers exhibit a weak ferromagnetic order. Such ferromagnetism in the PbTiO 3 layers near the interface is related to charge transfer from V to Ti and the ferroelectric polarization of PbTiO 3. The electronic structure of the superlattices indicates that spin-polarized two-dimensional polar metals are obtained for all orientations. In addition, different superlattice orientations correspond to different bandwidths of 3 d orbitals of SrVO 3 due to the dimensional confinement effect. The present work suggests a possible scenario by which two-dimensional polar metals and the coupling between the structural, electronic, and magnetic degrees of freedom in oxide superlattices can be extensively explored. [ABSTRACT FROM AUTHOR]

Published
2019
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221. Comparative Analysis and Isoform-Specific Therapeutic Vulnerabilities ofKRASMutations in Non–Small Cell Lung Cancer

Author

Ricciuti, Biagio, primary, Son, Jieun, additional, Okoro, Jeffrey J., additional, Mira, Alessia, additional, Patrucco, Enrico, additional, Eum, Yoonji, additional, Wang, Xinan, additional, Paranal, Raymond, additional, Wang, Haiyun, additional, Lin, Mika, additional, Haikala, Heidi M., additional, Li, Jiaqi, additional, Xu, Yue, additional, Alessi, Joao Victor, additional, Chhoeu, Chhayheng, additional, Redig, Amanda J., additional, Köhler, Jens, additional, Dholakia, Kshiti H., additional, Chen, Yunhan, additional, Richard, Elodie, additional, Nokin, Marie-Julie, additional, Santamaria, David, additional, Gokhale, Prafulla C., additional, Awad, Mark M., additional, Jänne, Pasi A., additional, and Ambrogio, Chiara, additional

Published
2022
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232. REPTOR/CREBRF encode key regulators of muscle energy metabolism

Author

Saavedra, Pedro, primary, Dumesic, Phillip A., additional, Hu, Yanhui, additional, Jouandin, Patrick, additional, Binari, Richard, additional, Wilensky, Sarah E., additional, Filine, Elizabeth, additional, Rodiger, Jonathan, additional, Wang, Haiyun, additional, Spiegelman, Bruce M., additional, and Perrimon, Norbert, additional

Published
2021
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242. Synergizing the internal electric field and ferroelectric polarization of the BiFeO3/ZnIn2S4 Z-scheme heterojunction for photocatalytic overall water splitting.

Author

Zhang, Jian, Zhang, Ying, Li, Lutao, Yan, Wei, Wang, Haiyun, Mao, Weiwei, Cui, Yan, Li, Yonghua, and Zhu, Xinbao

Abstract

Coupling the internal electric field and ferroelectric polarization via the modulation of surface electronic structures to achieve high carrier separation and migration efficiency is attractive but challenging in solar-to-chemical energy conversion. Herein, we report that coating ultrathin ZnIn2S4 nanoflakes on BiFeO3 polyhedron microparticles constructs a ferroelectric polarization and internal electric field enhanced Z-scheme heterojunction photocatalyst (BiFeO3/ZnIn2S4). Benefiting from the efficient photogenerated carrier separation and migration processes triggered by powerful spontaneous polarization and internal electric field, respectively, the nanocomposites exhibit strong half-reaction activity over hydrogen and oxygen evolution. Importantly, the optimal nanohybrid photocatalyst (ZB-3) delivered superior photocatalytic overall water splitting activity (H2: 87.3 μmol g−1 h−1, O2: 42.3 μmol g−1 h−1) with an apparent quantum efficiency of 1.12% at 420 nm in pure water under visible light irradiation, the highest activity reported thus far for ferroelectric-based heterojunction photocatalysts. The novel strategy of synergizing internal electric field and ferroelectric polarization via hybridization has been proposed to boost the separation and transfer efficiency of photogenerated charges in ferroelectric materials. [ABSTRACT FROM AUTHOR]

Published
2023
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243. The "Light Knife" for Gastric Cancer: Photodynamic Therapy.

Author

Wang, Haiyun, Ewetse, Maswikiti Paul, Ma, Chenhui, Pu, Weigao, Xu, Bo, He, Puyi, Wang, Yunpeng, Zhu, Jingyu, and Chen, Hao

Subjects
*PHOTODYNAMIC therapy, *STOMACH cancer, *CANCER treatment, *HEAD & neck cancer, *ESOPHAGEAL cancer
Abstract

Photodynamic therapy (PDT) has been used clinically to treat cancer for more than 40 years. Some solid tumors, including esophageal cancer, lung cancer, head and neck cancer, cholangiocarcinoma, and bladder cancer, have been approved for and managed with PDT in many countries globally. Notably, PDT for gastric cancer (GC) has been reported less and is not currently included in the clinical diagnosis and treatment guidelines. However, PDT is a potential new therapeutic modality used for the management of GC, and its outcomes and realization are more and more encouraging. PDT has a pernicious effect on tumors at the irradiation site and can play a role in rapid tumor shrinkage when GC is combined with cardiac and pyloric obstruction. Furthermore, because of its ability to activate the immune system, it still has a specific effect on systemic metastatic lesions, and the adverse reactions are mild. In this Review, we provide an overview of the current application progress of PDT for GC; systematically elaborate on its principle, mechanism, and the application of a new photosensitizer in GC; and focus on the efficacy of PDT in GC and the prospect of combined use with other therapeutic methods to provide a theoretical basis for clinical application. [ABSTRACT FROM AUTHOR]

Published
2023
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244. Capacity Configuration Optimization of Cogeneration System for Independent Photohydrogen Fuel Cell.

Author

SHEN Hangyu, FAN Xiaochao, SHI Ruijing, WANG Weiqing, WANG Haiyun, and CHENG Zhijiang

Abstract

In order to solve the problem of heat dissipation in the process of producing hydrogen from electrolytic water and generating electricity from fuel cells, an independent photohydrogen fuel cell thermoelectric combined supply system was designed according to the principle of water cooling heat dissipation between electrolytic cell and fuel cell. Based on this model, a control strategy was formulated to coordinate the output order and size of each module, which solved the inefficiency of electrolytic cell in low power operation zone. The capacity allocation model was established with the objective function of optimal comprehensive cost, and the optimal capacity allocation result of the system was obtained by using the particle swarm algorithm. The simulation results show that the overall cost of the configuration scheme proposed can be reduced by 2.2% compared with the traditional configuration scheme, and it can meet the same starting and ending states of the hydrogen storage tank and the heat storage tank during the operation cycle. The long-term energy supply effect of the system is excellent, which can provide a reference value for the capacity configuration of the current stand-alone photohydrogen fuel cell cogeneration system. [ABSTRACT FROM AUTHOR]

Published
2022
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