201. A Young Woman With Blurred Vision and Distal Paresthesias.
- Author
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Kung NH, Bartlett NL, Yaseen NR, Van Stavern GP, and Bucelli RC
- Subjects
- Adult, Diagnosis, Differential, Female, Humans, Magnetic Resonance Angiography, Magnetic Resonance Imaging, Tomography Scanners, X-Ray Computed, Vascular Endothelial Growth Factor A blood, Paresthesia complications, Paresthesia diagnosis, Vision Disorders complications, Vision Disorders diagnosis
- Abstract
A 29-year-old woman presented with blurred vision and distal paresthesias. Her initial evaluation revealed severe bilateral optic disc edema with distal lower-extremity sensory and motor deficits and electrodiagnostic evidence of a length-dependent mixed demyelinating and axonal polyneuropathy. The results of routine diagnostic testing, including laboratory tests, magnetic resonance imaging, and lumbar puncture, were nondiagnostic. A targeted biopsy was ultimately required for diagnosis. In this article, we discuss the differential diagnosis and outline the clinical evaluation indicated for a patient presenting with demyelinating polyneuropathy and concurrent papilledema.
- Published
- 2015
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