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Objective To determine the relationship between buccal bone and soft tissue thickness at teeth in the premaxilla by means of non-invasive registration methods. Materials and Methods Buccal bone thickness at central incisors, lateral incisors and canines was measured at five reference points (1–5 mm from the top of the alveolar crest) on CB-CT scans of 21 patients. The corresponding buccal gingival thickness was measured by the use of an ultrasonic device. Spearman's correlation coefficient was calculated to assess the correlation between buccal bone and soft tissue thickness at each tooth type. Results Mean buccal bone thickness (SD) at central incisors, lateral incisors and canines was 1.07 mm (0.34 mm), 1.16 mm (0.54 mm) and 0.98 mm (0.37 mm), respectively. For central incisors, 68% of all sites had a thickness

Aim To establish the added effect of a chemotherapeutic cooling solution in an ultrasonic device on clinical parameters of periodontal inflammation following non-surgical periodontal therapy. Methods The MEDLINE-PubMed, Cochrane-CENTRAL and the EMBASE databases were searched. Probing pocket depth(PPD) and clinical attachment level(CAL) and their changes were selected as outcome variables. Subgroup analyses were performed according to the following active ingredients: essential oils(EO), povidone-iodine(PVP) and chlorhexidine(CHX). Results Screening of 100 unique papers resulted in 14 eligible publications, including 16 comparisons. The meta-analysis(MA) showed that when the ultrasonic cooling solution had adjuvant chemotherapeutic properties, the difference of means(DiffM) for end value PPD-0.12(95%CI:-0.42;0.18) and for CAL, DiffM-0.13(95%CI:-0.39;0.14). None of these were statistically significant, and the findings were supported by the overall descriptive analysis. Subgroup analysis only revealed a small effect for PVP(DiffM=-0.23,95%CI:-0.43;-0.02) with respect to CAL(p=0.03). Conclusions The collective evidence indicates that overall, no additional effects were observed. There is a “very weak” recommendation based on the sub-analysis showing that in conjunction with PVP, a very small gain in CAL may be expected. For the use of CHX or EO, the added effect can be considered to be ‘zero’. Therefore, the strength and direction of the recommendation emerging from this review is against their use. This article is protected by copyright. All rights reserved.

Accurate determination of intravesical residual urine volume as well as bladder capacity is of significant importance in children. The ability to confirm these measurements non invasively in children avoids discomfort, urethral trauma and the introduction of urinary tract infection. Also, by avoiding the need for catheterization this technique permits more physiological assessment and allows for repeated examinations without fear and anxiety on the part of the patients. In this prospective study we assess the accuracy of the real time, hand held, ultrasonic device using suprapubic views and biplanar technique to determine intravesical volumes. Real time ultrasonography with suprapubic views and the described bi-planar technique to determine intravesical urine volume is simple, accurate and reproducible. It also is rapid and noninvasive, and can detect accurately an empty bladder in children. A strong correlation was found between the estimated bladder volume with our method and voided urine volume (0 ml, residual volume) .This study concluded that the modality used in this study has the potential to provide useful and reproducible information in the clinical evaluation of bladder function in children.DOI: http://dx.doi.org/10.3329/jdnmch.v17i2.12199 J. Dhaka National Med. Coll. Hos. 2011; 17 (02): 4-7

Three flat pasta types dried by low temperature (LT), high temperature (HT), and very high temperature (VHT) drying profiles were analyzed. The starch properties of these pastas, cooked at different temperatures for different times, were investigated. The starch properties were examined by observing starch swelling with a scanning electron microscope (SEM), identifying the phase difference with an ultrasonic device, and determining the water absorption and gelatinization rate with the BAP method and X-ray diffraction. The SEM images revealed expanded and gelatinized starch granules during cooking pasta and increased with drying temperature. The water absorption of pasta increased with cooking temperatures and times, and the trend was LT > HT > VHT-dried pasta. The gelatinization rate of pasta increased with cooking time and temperature. The X-ray diffractograms of pasta cooked less than 12 min showed typical A-type X-ray diffraction patterns, while in pasta cooked for 12 min, V-type diffraction was observed. Uncooked pasta showed an enhanced peak at about 2θ = 20°, which indicated the generation of high levels of amylose–lipid complexes. The present study found that these changes occurred during drying and may affect pasta starch characteristics.

Objective: To evaluate the palatal soft tissue thickness among placement sites of temporary anchorage devices (TADs) in late mixed, early permanent and permanent dentition. Materials and Method: The sample consisted of three groups; 42 late mixed dentition (mean age = 11.0 years), 41 early permanent dentition (mean age = 13.8 years), and 38 permanent dentition (mean age = 23.1 years). Soft tissue thickness was measured intraorally with an ultrasonic device using a grid of 27, 4x4 mm2 squares to delineate the measurement points. Repeated measures analysis of variance was performed to analyze the data. Results: There was a significant difference in soft tissue thickness among dentition groups with the permanent dentition group showing the highest values (P < 0.001). In each group, the thickness significantly increased from median to lateral and from anterior to posterior sites. Furthermore, the thickness showed a significant difference according to the arch form and gender (P < 0.05). However, there were no significant differences according to irregularity index and Angle classification. Conclusions: The soft tissue thickness of the palate increases from the late mixed to permanent dentition. These findings may be helpful for clinicians to enhance their successful application of TADs in the palate.

This study aims to examine the effects of massages using various tools being frequently applied in skin care centers. It suggests the most effective method based on the comparative analysis on the body heat changes before and after the massages and also provides foundational data to develop back treatment programs. This research conducted manual, ultrasonic device, and also suction massages from July 3rd till 10th, 2011 to women at the age of 35 to 45 living in Gwangju, Jeonnam. And five of them were arranged for each tool. The body heat changes before the massages and after the 20-minute massages were measured with the body heat diagnostic device of thermograph DITI IRIS-XP. The collected data went through the t-test using SPSS 18.0. According to the result, the body temperature increased significantly before and after the manual massage from to (p to (p to (p

We describe the construction of a ultrasonic device suitable for micro patterning particles and cells for tissue engineering applications. The device is formed by seven transducers shaped into a heptagon cavity. By exciting two and three transducers simultaneously, lines or hexagonal shapes can be formed with beads and cells. Furthermore, phase control of the transducers allows shifting the standing waves and thus patterning at different positions on a surface in a controlled manner. The paper discusses direct patterning of mammalian cells by ultrasound "stencil".

ObjectivesIn laparoscopic liver resection, multiple options for parenchymal transection techniques exist; however, none have emerged as superior. The aim of this study was to compare operative characteristics and outcomes between bipolar compression and ultrasonic devices used for parenchymal transection during laparoscopic liver resection.MethodsA review of a prospective hepatopancreatobiliary database from December 2002 to August 2009 identified 54 patients who underwent laparoscopic liver resection with parenchymal division using either a bipolar compression (n= 35) or an ultrasonic (n= 19) device. Operative data, histology and 90-day complication rates were compared between the groups using analysis of variance (anova) and Pearson's chi-squared test.ResultsThe two groups did not differ significantly in terms of age, body mass index, parenchymal steatosis/inflammation or number of segments resected. A shorter time of parenchymal transection was noted for the bipolar compression device (median: 35min; range: 20–65min) vs. the ultrasonic device (median: 55min; range: 29–75min) (P < 0.001). Median total operative time was also shorter using the bipolar compression device (130min) than the ultrasonic device (180min) (P= 0.050). No significant differences between device groups were noted for estimated blood loss, complications of any type or liver-specific complications.ConclusionsBipolar compression devices may offer advantages over ultrasonic devices in terms of decreased transection time and total operative time. No differences in postoperative complications in laparoscopic liver resection emerged between patients operated using the devices.

On what occasion does ultrasonography demonstrate its power? When and where can we, as the ones with the knowledge and skills to utilize this diagnostic technique, demonstrate our power? In daily clinical practice, where normal medical services are available, ultrasonography is just another diagnostic imaging technique. However, ultrasonography is able to tell us what is happening to the patient in front of us. Whether we understand it or not is up to our skills as clinicians. In order to understand the pathophysiology of our patients with information obtained by ultrasonography, in addition to a full knowledge of ultrasonography, it will be necessary to obtain profound insight on their condition, physical findings and laboratory data other than ultrasonographic findings. Being a cardiologist who specializes in ultrasonography, I believe that ultrasonography should not just be applied as a means of diagnostic imaging, but that we should also possess the focus, determination and passion to comprehend pathophysiology from echo images. On the other hand, how is ultrasonography used in nonordinary clinical practice? I am currently on a bullet train bound for Hiroshima. Sitting next to me is a cardiac surgeon who is sub-specialized in vascular ultrasonography. We both specialize in ‘‘ultrasonographic diagnosis’’ and are also colleagues who carried out leg vein echo screening on deep venous thrombosis (DVT) at shelters during the unprecedented disaster of the Great East Japan Earthquake in March 2011, of which we were also victims. At the time of the disaster, the Japan Society of Ultrasonics in Medicine sent portable ultrasonic devices to the stricken areas, which we received along with passion and support of the many people who sent them. We could therefore perform DVT screening at shelters and cooperate with central hospitals when necessary. In non-ordinary practice such as a time of disaster, it is our passion and expertise as ultrasonography specialists that make ultrasonography so powerful. In August 2014, another disaster hit Japan in the form of a deadly landslide that inflicted immense damage to a mountainous region of Hiroshima. I would like to offer my deepest condolences for the people who perished in the horrific event. I would also like to express my great gratitude to the many people working in medical teams established to provide shelter-based treatment for victims. Lessons learnt from the Great East Japan Earthquake have been put to good use. I will be joining one of the teams as an outside medical support staff member, and I will be involved in DVT screening at the shelters, using a portable ultrasonic device borrowed from the Japan Society of Ultrasonics in Medicine. This emergency system of lending ultrasonic devices was established during the Great East Japan Earthquake, thus enabling the passion and support of countless numbers of people, in Japan and overseas, to be both given and received. By the time this article is published, we will have already celebrated the beginning of a new year. A year in which I hope to enter a new era, spearheaded by the passion and determination of those who perform ultrasonography, demonstrating its power, leading to a better future.

We work in research and development of novel needle biopsy system in order to extract muscle tissue with form of fiber. The system consists of an ultrasonic device, an angular adjustment implement, and a needle. The needle has curved shape so penetrates from skin surface perpendicularly and takes route parallel to bone in muscle tissue. We produced prototype of needle setup, conducted the verification experiment using agaerGEL. The shape of developed needle has been verified, the result told us improvement of its material and manufacture method.

Adequate denture hygiene can prevent and treat infection in edentulous patients. They are usually elderly and have difficulty for brushing their teeth. OBJECTIVE: This study evaluated the efficacy of complete denture biofilm removal using chemical (alkaline peroxide-effervescent tablets), mechanical (ultrasonic) and combined (association of the effervescent and ultrasonic) methods. MATERIAL AND METHODS: Eighty complete denture wearers participated in the experiment for 21 days. They were distributed into 4 groups (n=20): (1) Brushing with water (Control); (2) Effervescent tablets (Corega Tabs); (3) Ultrasonic device (Ultrasonic Cleaner, model 2840 D); (4) Association of effervescent tablets and ultrasonic device. All groups brushed their dentures with a specific brush (Bitufo) and water, 3 times a day, before applying their treatments. Denture biofilm was collected at baseline and after 21 days. To quantify the biofilm, the internal surfaces of the maxillary complete dentures were stained and photographed at 45º. The photographs were processed and the areas (total internal surface stained with biofilm) quantified (Image Tool 2.02). The percentage of the biofilm was calculated by the ratio between the biofilm area multiplied by 100 and the total area of the internal surface of the maxillary complete denture. RESULTS: The Kruskal-Wallis test was used for comparison among groups followed by the Dunn multiple-comparison test. All tests were performed respecting a significance level of 0.05. Significant difference was found among the treatments (KW=21.18; P

An ultrasonic device with frequency of 20 kHz was used to investigate the effect of different operational parameters such as ultrasonic power, temperature and initial molecular weight on dextran degradation. Results show that the molecular weight of dextran can be controlled by ultrasonic treatment. Higher the ultrasonic power and lower the temperature could increase the degradation rate (R).The initial molecular weight plays an important role in at the initial stage of dextran degradation (within 20 minutes). A smilar limiting molecular weight (Mw≈8.7×104) was obtained after 2 hours ultrasonic treatment for four different initial molecular weight dextrans, suggesting that the limiting molecular weight is independent on the initial molecular weight of dextran. Ultrasonic treatment can be used as a safe, simple and effective method to control the molecular weight of dextran.

Background Preservation of lip sensation is crucial in ablative surgery of mandibular tumors. When tumor control does not necessitate sacrifice of the inferior alveolar nerve (IAN), as in some cases of benign tumors of the lower jaw, attempts may be made to spare the nerve. The authors present and discuss their experience with an ultrasonic device in the treatment of benign tumors of the jaw in correspondence of the IAN. Materials and Methods Five patients with tumoral lesions involving the IAN underwent surgery with an ultrasonic surgical device (Sonopet Omni Surgical System; Stryker, Kalamazoo, MI). Results Fine, delicate movements allowed the surgeon to remove bone without damage to surrounding tissue. Three of 5 patients did not present intraoperative or postoperative complications that could be attributed to the Sonopet. Two cases were partial failures. In 1 case, postoperative dysesthesia was encountered, and in the other case, intraoperative transection of the nerve occurred. Conclusion The Sonopet ultrasonic bone curette proved to be highly useful in surgical procedures close to the IAN because it does not produce heat or cause mechanical injury to the neurovascular bundle. Application of this instrument may provide improved ability to preserve sensibility of the chin and lower lip in patients affected by lesions in proximity to the IAN.

The preparation of recently recovered fossil bones often consists of removing sediment by means of mechanical cleaning. A variety of tools are commonly employed in this process (hammers and chisels, air abrasion devices, pneumatic engraving pens, etc). Another tool, however, has received less attention in the literature: the ultrasonic scaler. An ultrasonic scaler is an ultrasonic device used by dentists to remove hard calculus deposits and stains from the teeth. In this article, we describe the preparation of the human mandible ATD6-112 from the Pleistocene site of Gran Dolina (Atapuerca, Spain) with an ultrasonic scaler. This article aims to describe the advantages and drawbacks of this tool for use in some cleaning processes. La préparation des ossements fossiles récemment découvert dans les sites archéologiques, consiste souvent à enlever le sédiment par nettoyage mécanique. Pour cela, une variété d’outils a été largement utilisée (marteaux et burins, dispositifs d’abrasion d’air, stylos pneumatiques). Moins rapportée, est l’utilisation d’un détartreur ultrasonique (un appareil à ultrasons utilisé par les dentistes pour enlever le tartre et les taches des dents). Dans cet article, nous décrivons la préparation réussie de la mandibule humaine ATD-112 du site archéologique pléistocène de Gran Dolina (Atapuerca, Espagne) par détartreur ultrasonique. Cet article vise à exposer les avantages et les inconvénients de cet outil à des fins de nettoyage.

Purpose: To validate a novel ultrasonic sensor for logging reading distances. In addition, this device was used to compare the habitual reading distances between low and high myopes. Methods: First, the stability and sensitivity of the ultrasonic device were determined by repeated measures using artificial targets. Then, thirty Hong Kong Chinese (20‐30 years) were recruited, of whom fifteen were considered to be high myopes (mean ± S.D. = )8.7 ± 0.5 D) and 15 to be low to non-myopes (mean ± S.D. = )2.0 ± 0.2 D). Each subject read a newspaper with their habitual visual aid continuously for 10 min in two sessions at their preferred working distance(s). The reading distances were recorded continuously using a novel nearwork analyzer. The modal working distance was considered as the ‘habitual’ reading distance. In addition, habitual reading distance was reported orally by each subject. Results: The nearwork analyzer gave accurate and repeatable measurements over a range of distances and angles. Using this instrument, high myopes were found to have a significantly shorter reading distance than low myopes or nonmyopes (mean ± S.D. = 35.9 ± 9.8 cm vs 50.9 ± 24.8 cm; two-sample t-test, p = 0.04, df = 18). The reading distances reported orally by the subjects were not correlated with those recorded by the nearwork analyzer. Conclusions: The nearwork analyzer was found to be an effective tool for measuring nearwork reading distance in a small group of emmetropic and myopic adults over a 10 min interval. Differences between the reading distance between high myopes and low/non-myopes was detected by the device. Further study is needed to determine if a closer working distance is a cause or effect of myopia development.

In order to carry out non-destructive testing on standing trees, explore the propagation characteristics and the influence factors of the ultrasonic wave spreading in the standing trees. Take simon poplar as the research object, Resistograph were employed to test 30 sample (simon polar) standing trees and it gave a preliminary estimate of the internal defects in the samples, and RSM-SYS5 ultrasonic device were employed to test the ultrasonic propagation velocity spreading in simon poplar standing trees, with the statistics of the ultrasonic propagation velocity spreading separately in the health trees and standing trees with defects, and did a regression analysis of the relationship between the size of the defacts and the ultrasonic propagation velocity. The results show that: 1) When the diameter of sample trees are between 30 and 55cm, the radial velocity of ultrasonic spreading in healthy simon poplar standing trees are in the range of 1029.96m/s ~ 1200m/s, all more than 1000m/s; however, when there are defects in simon poplar standing trees, the ultrasonic radial velocity are less than 1000m/s. 2) The defacts in standing trees have an significant influence on the ultrasonic radial propagation velocity spreading in simon poplar standing trees, defect size and the radial velocity is significantly negatively correlated, and the correlation coefficient R is 0.887.

The aim of the study was to establish whether juveniles with a Class II malocclusion change the neuromuscular control of mandibular movements during the course of orthodontic treatment with removable functional appliances (RFAs). Neuromuscular control can be indirectly evaluated by recording cyclic planar mandibular movements which were freely carried out by the patients (28 girls, 14 boys, aged 11.1 ± 1.1 years at the start of treatment) and measured with an ultrasonic device before, during, and after Class II functional appliance therapy, with either an activator or a bite jumping plate. The cyclic movements represented simultaneous rotations of the mandible around a maxillary and mandibular fixed axis (MFHA) and could be characterized by μ(α)-diagrams (μ = swing angle of MFHA, α = mouth opening angle) and path length ( L ) of the MFHA. The μ(α)-diagrams clearly divided into four parts: movement representing protrusion, mouth opening, and two parts of backward closing as known from Posselt diagrams. Parameters from the Posselt and μ(α)-diagrams were checked by one-factor analysis of variance on a 5 per cent significance level for group dependency. For one-third of the patients investigated, no significant changes were seen in any parameter pre- or post-therapy. However, patients showing an initially large mouth opening capacity or a very short condylar path changed their neuromuscular control to that of Class I subjects. Analysis of μ(α)-diagrams provides the possibility of assessing changes in the neuromuscular control of the mandible during Class II treatment.

Objective The purpose of this study was to present a new surgical preservation technique for teeth with incomplete vertical root fracture. Study design Seventeen patients with 1 endodontically treated maxillary anterior tooth in which an incomplete vertical root fracture involving only the buccal side was suspected underwent a flap elevation procedure to visualize the pattern of bone loss and assess the type of root fracture. If the preoperative diagnosis was confirmed, a groove following the fracture line was prepared using retro-tips driven by an ultrasonic device and sealed with mineral trioxide aggregate after filling of the bone defect with calcium sulfate. Results A total of 10 vertical root fracture repair procedures were performed. At 12 months' follow-up, all cases showed clinical and radiographic success. After 33 months, 7 patients were available for a follow-up: 5 cases remained successful, and 2 teeth (lateral incisors) failed. Conclusions The present surgical approach for preservation of teeth with incomplete vertical root fracture demonstrated satisfactory results regarding clinical outcome.

Laparoscopic liver resection has been increasingly gaining popularity worldwide with the advance of laparoscopic instruments and techniques in the last decade. Laparoscopic approach for left side hepatic lesion has become the standard procedure. In this video manuscript, we showed the technique of laparoscopic non-anatomical left lateral sectionectomy for tumor located in segment 3. The first and most important step is to identify hepatic artery to segment 2 and 3 and mark the transection border according to ischemic line. Following that, liver parenchyma transection begins with laparoscopic ultrasonic device and/or other energy devices. Intrahepatic vessels encountered are divided with metallic or Hem-o-lok clips. Finally, left hepatic vein is divided by laparoscopic linear stapler.

The aim of the present study is to intraoperatively measure the distance from the bottom of the osteotome to the inferior alveolar canal (IAC) and maxillary sinus floor using a novel ultrasonic device and to compare the measurements to those using conventional radiographs.Patients scheduled for dental implant placement in the posterior regions were recruited for this pilot study. Mucoperiosteal flaps were elevated, and a recipient site was initiated using a standardized 2-mm-diameter pilot drill. The distance from the bottom of the osteotome to the IAC and maxillary sinus floor was assessed using a newly developed ultrasonic device and compared to a standard panoramic radiograph that was used to measure the same residual distance from the bottom of the drill.Fourteen consecutive patients (21 implants) were enrolled. Eleven implants were placed in posterior mandibles, and 10 implants were placed in posterior maxillae. The mean +/- SE radiographic distance from the apex of the pilot drill to the nearest cortical bone was 5.64 +/- 0.51 mm, which was very similar to the distance measured by the ultrasonic device (5.22 +/- 0.37 mm; P = 0.341). In posterior mandibles (n = 11), the distances were 5.18 +/-0.61 mm (radiographic) and 5.26 +/- 0.61 mm (ultrasonic), which were not statistically significant (P = 0.593). A very strong positive correlation was observed between the two measurements in mandibles (r = 0.967; P = 0.0001).The results of this in vivo study support the value of this ultrasonic system in measuring the residual osseous depth from the bottom of the osteotome to the roof of the IAC.

SUMMARYA laboratory experiment was conducted to determine the effect of ultrasound (US) treatment on seed germination of chickpea, wheat, pepper and watermelon. All tests were carried out at 40 kHz in a water bath ultrasonic device varying two factors, treatment duration (5, 10, 15, 30, 45 or 60 min) and germination temperature (15 or 20 °C). Parallel tests were run in which seeds were soaked in water without sonication in order to eliminate the effect of water from US test results. The effects of US on seed germination varied between crops and were more obvious on germination speed, expressed as germination rate index (GRI), rather than on germination percentage (GP). In particular, US treatment significantly increased the GRI of chickpeas, wheat and watermelon, resulting in a maximum increase of 133% (at 45 min), 95% (30 min) and 45% (5 min), respectively, above control seeds. The beneficial effects of US on the GRI of these crops were observed at both 15 and 20 °C, suggesting that US treatment offers a practical priming method to overcome the slow germination that may occur at low temperatures. Water-soaking treatment improved the GP of both chickpea and pepper seeds by 59 and 24%, respectively, compared to the control but neither water nor US had any positive effect on pepper GRI. Post-treatment measurement of moisture content of these seeds produced variable results depending on crop species and US treatment duration. Results of this research indicated that US treatment effectively enhanced speed of germination of chickpea, wheat and watermelon seeds. This increase in speed of germination may improve early field establishment of these crops in the semiarid Mediterranean region and thus needs further investigation. The US technique may also be very useful for plant propagators in nurseries to achieve fast seedling establishment of watermelon.

Aim: This study aims to evaluate the retrieval outcome of the separated endodontic instrument by endodontic board residents. Materials and Methods: Records of 450 endodontic cases with separated endodontic instruments treated by endodontic Saudi board residents were randomly selected. The evaluation was based on the tooth type, type of fractured instrument, incidence and anatomical location in the root canal and if the instrument was retrieved, bypassed, or left. Data were statistically analyzed using IBM-SPSS.22. Results: A total of 84 (19%) separated instruments were identified. Thirty-four cases (7.55%) with separated instruments out of the total evaluated cases were done by residents. The incidence between hand stainless steel and nickel-titanium instruments was statistically significant (P < 0.05). The separated instruments were found more in the mandibular molars, i.e., 44 (52.4%). They were observed more in the buccal canal of the maxillary premolars and mesiobuccal canals of mandibular and maxillary molars. Fifty-seven (67.9%) of the separated fragments were located in the apical third of the root. Thirty-six (34.3%) were retrieved, 20 (19.0%) were bypassed, and 34 (32.4%) were left while 15 (14.3%) were managed by surgery. The ultrasonic device was more active in removing the separated instruments. Conclusions: Regardless of little experience of the endodontic residents, they were successfully managed to remove or bypass most of the separated instruments. Ultrasonic device was very helpful in removing the separated instrument.

Currently the primary methods for obtaining hemostasis during minimally invasive surgery include systems that incorporate either ultrasonic or radiofrequency energy. Although the use of improved energy systems has dramatically facilitated laparoscopic dissection and hemostasis, the threat of thermal collateral damage remains and detracts from the usefulness of these devices. Traditionally the thermal spread from these instruments has been determined with a combination of in situ dynamic thermography and histopathologic studies that result in varying degrees of cross-correlation. The ability to obtain a real-time subsurface tissue thermal profile without the use of thermography in either an electrosurgical or ultrasonic device is feasible with a microthermistor placed at a predetermined distance and depth from the instrument tool edge. A comparison with traditional thermographic measurements and their correlation with histologic study are warranted with future studies.

Objective: The aim of this study was noninvasive evaluation of voiding function in children with cerebral palsy. Design: Sixty children with cerebral palsy were enrolled in the study. Urinary system symptoms were recorded. Uroflowmetric tests were carried out, and postvoid residual volume was measured immediately after voiding by using a portable ultrasonic device developed for children. The expected age-related bladder capacity was calculated and compared with the observed bladder capacity. Uroflowmetric curves were evaluated and classified as normal (bell-shaped) and abnormal. Results: Thirty-three of the children (55%) were symptomatic. In 1 7 (28.3%) of the children, postvoid residual urine was observed. There was a statistically significant difference between the expected bladder capacity (271.6 ± 38.3 ml) and the observed bladder capacity (154.5 ± 111.8 ml) (P < 0.001). Observed bladder capacity was lower than the expected bladder capacity in 56 (93.3%) of the children. In the evaluation of the uroflowmetric charts, 22 (36.7%) children had abnormal curves. Conclusions: Bladder capacity is decreased in most children with cerebral palsy, and postvoid residue is present in an important proportion. Uroflowmetry and portable ultrasonic device combination is a noninvasive, well-tolerated, and efficient method in the first line evaluation of lower urinary tract function in children with cerebral palsy.

The increasing incidence of reports of damage caused by Eurasian badgers ( Meles meles ) in UK urban environments requires the development of effective, humane, non-lethal solutions. Ultrasonic deterrents are widely available to the public and are sold as a humane solution to the presence of unwanted animals in urban gardens. The reported failure of some ultrasonic devices may be caused by habituation of target animals to the devices and the lack of association with a negative, physical stimulus. We tested the ability of a commercially available, motion sensor-triggered ultrasonic device and a motion sensor-triggered water jet device, alone and in combination, to alter badger activity and feeding at baited plots. The ultrasonic device, whether used alone or in combination with the water jet, was associated with significantly higher badger activity at baited plots in comparison to control plots, and bait consumption was higher when the ultrasonic device was used alone. When the water jet was used alone, bait consumption was significantly reduced in comparison to control plots, but badger activity was not. There was no evidence to suggest that aversion to the ultrasonic device could be reinforced by the water jet, but some evidence to suggest that ultrasonic devices may have attracted badgers to baited plots. While the effects of the water jet on bait consumption were statistically significant, they were also very small (a 12% difference between the treatment and control fitted means). We conclude that neither device, used alone or in combination, present effective solutions to the growing problem of urban badger damage.

Purpose: The merits of laparoscopic sealing devices have been poorly characterized. The purpose of this study was to compare two bipolar sealing devices [LigaSure V (LS) and Gyrus PK (GP)], an ultrasonic device [Harmonic Scalpel ACE (HS)] and a novel device using nanotechnology [EnSeal PTC (ES)]. Materials and Methods: The ability of all four 5 mm devices to seal 5 mm bovine arteries was tested under controlled temperature and humidity in accordance with manufacturer specifications. Study endpoints included lateral thermal spread, time to seal, burst pressure, smoke production and subjective (blinded review of video clips) and objective (measured using an aerosol monitor) effect upon visibility. Results: The HS demonstrated the least thermal spread. The LS (10.0 secs) and GP (11.1 secs) had the fastest sealing times (p� 0.001 for both) when compared to ES (19.2 sec) and HS (14.3 sec). Mean burst pressure values were: LS 385 mm Hg, GP 290 mm Hg, ES 255 mm Hg and HS 204 mm Hg. The HS had the best subjective visibility score and the lowest objective smoke production (2.88 ppm) compared to the GP (74.1 ppm), ES (21.6 ppm) and LS (12.5 ppm), (p� 0.01 for all). Conclusions: The LS has the highest burst pressure and fastest sealing time and was the highest rated overall. The HS produced the lowest thermal spread and smoke but had the lowest mean burst pressure. The GP had the highest smoke production, and variable burst pressures. Despite employing nanotechnology, the ES device was the slowest and had variable burst pressures.

Forces underneath the coraco-acromial vault during elevation of the arm were evaluated with a dynamic shoulder model. The deltoid muscle and the rotator cuff muscles were simulated with a hydrodynamic device, in ten autopsy specimens. Controlled cycles of glenohumeral joint motion were initiated with computerised regulation. An ultrasonic device measured the position of the arm in all spatial orientations. Capacitive sensors recorded forces underneath the coraco-acromial vault. The mean force during one cycle of elevation averaged 13.9 Newton +/- 12.5 Newton underneath the coraco-acromial ligament and 3.44 Newton +/- 4.37 Newton underneath the coracoid process. The peak force averaged 37.8 Newton +/- 33.2 Newton underneath the acromion, 3.03 Newton +/- 2.62 Newton underneath the coraco-acromial ligament and 6.93 Newton +/- 7.38 Newton underneath the coracoid process. The force markedly increased at the final stage of arm elevation and during early reverse-elevation in most specimens, corresponding to the painful arc sign. In some specimens, the force under the coracoid process exceeded the force under the acromion. Osteophytes protruding into the subacromial space may lead to a concentration of force and to high regional pressures.

The prevalence of saphenofemoral incompetence in a series of 105 consecutive patients undergoing saphenofemoral ligation as part of an operation for primary varicose veins was determined using a directional continuous-wave Doppler ultrasonic device. Saphenofemoral incompetence was correctly predicted in 97% of limbs. Using conventional clinical methods, incompetence was correctly predicted in 82% of limbs. This difference was highly significant (P less than 0.01 McNemar). It is concluded that a directional Doppler ultrasonic assessment is a useful aid in the pre-operative determination of saphenofemoral incompetence.

Aim:We have recently tested a surface detection system based on a conventional dental ultrasonic scaler in vitro. The aim of the present study was to investigate sensitivity and the specificity of the detection device in vivo. Material and Methods:Subgingival buccal surfaces of 63 arbitrarily selected periodontally compromised teeth were scanned intra-orally, while the supragingival positions of the insert, along with the corresponding signals of the detection system, were saved as separate files. After extraction, the surface detection results were evaluated by re-positioning the inserts’ position on the tooth in vitro and comparing the detection results with visual findings. Results:On the scanned tooth surfaces, there were 44 calculus spots, which covered 22.3% of all scanned surfaces (prevalence). The calculus-free surface was divided into ‘‘spots’’ mathematically. The device correctly classified 40 calculus and 125 cementum spots, whereas four calculus and 28 cementum spots were classified incorrectly. Calculus and cementum were discriminated with a sensitivity of 91% and a specificity of 82%. The positive and negative predictive values were 0.59 and 0.97. Conclusion:The surface detection device was able to clinically differentiate cementum and calculus in vivo. Therefore, this method may support the decision of whether continued subgingival scaling could damage the cementum.

BACKGROUND Small intrascleral foreign bodies of different materials, especially plastic or organic, can sometimes not easily--or not at all--be detected by routine X-ray examination or computed tomography scan. The aim of our study was to evaluate the usefulness of ultrasound biomicroscopy (UBM) with regard to the detection and localisation of such foreign bodies. METHODS An in vitro study with the preparation of a scleral tunnel on 12 porcine eyes was performed. Small foreign bodies of different types of material were placed in the tunnel. The UBM was performed with a Humphrey Ultrasound Biomicroscope, Model 840, to evaluate its diagnostic value in detecting and specifying these sclera-covered foreign bodies. RESULTS Even small foreign bodies of the anterior ocular segment of only 200 microm in size can be detected with the UBM due to the typical ultrasound patterns and artifacts. However, there is no diagnostic specificity for the corresponding material. CONCLUSION The UBM is a high-frequency ultrasonic device with an imaging depth of 5 mm and a spatial resolution of 100 microm. Therefore it is a useful alternative or, respectively, additional diagnostic tool to common imaging techniques like routine X-ray imaging or CT scans, especially in the detection of non-metallic objects. It can provide important information for the ophthalmic surgeon with regard to pre-operative evaluation of the eye. Furthermore, the UBM might even substitute operative exploration of foreign bodies if they are located in the anterior segment of the eye.

Objective: The aim of this randomised, split-mouth, controlled clinical trial was to evaluate the effectiveness of a controlled-release chlorhexidine chip (CHX chip) as an adjunctive therapy to scaling and root planing (SRP) with a newly developed ultrasonic device in supportive periodontal therapy (SPT). Materials and methods: Twenty patients with moderate-to-severe chronic periodontitis, displaying at least four sites with probing depth (PD) ≥5 mm and persistent bleeding on probing (BOP), were recruited for the study. The target sites were randomly treated with either a newly developed piezo-driven ultrasonic device VectorTM- or ultrasonic system (VUS) + CHX chip or VUS alone without adjunctive antimicrobial treatment. The clinical parameters, plaque index (PI), gingival index (GI), BOP, PD and clinical attachment level (CAL) were recorded at baseline and after 1, 3 and 6 months. Results: At baseline, there were no significant differences between test and control sites for any of the investigated parameters. The average reduction of PD and improvement in CAL was greater in the VUS + CHX chip sites than in sites treated with the VUS alone at 1, 3 and 6 months (P

We report on improved ultrasonic atomizer method of depositing the sensing films on quartz crystal microbalance (QCM) sensors. The main objectives of the present work were minimizing the sensor-to-sensor response variation, improving the sensing film stability, and reducing amount of materials used during coating (reducing time of coating). In order to achieve the goals, we have redesigned and refabricated large parts of the atomizer system reported previously. The main principle of the operation—deposition of the fine mist generated by the ultrasonic device remained unchanged. The largest modifications encompass introduction of the new, sealed deposition chamber, considerable reduction of the flow resistance, and control over the flow rates of the mist and air streams in the system. The paper reports the new configuration of the ultrasonic atomizer method, optimization of the atomizer system performance (deposition parameters) and the results of improved quality of sensors fabricated using the new system.

Objectives: The Vector® ultrasonic system provides root debridement supported by different abrasive irrigation fluids. The aim of this study was to investigate the clinical outcome of initial therapy with subgingival low-abrasive debridement. Material and Methods: Twenty patients, who had at least two teeth with pocket depths >5 mm in each quadrant, took part in this prospective randomized clinical study. Patients were treated in a split-mouth design as one test quadrant (1) subgingivally with Vector™ fluid polish (VU-H) and as three control quadrants, (2) with only supragingival polishing (PO-H), (3) with hand instruments (HI-H) performed by a hygienist and (4) with hand instruments (HI-D) performed by a dentist. At baseline, 3 and 6 months after treatment, pocket depths and attachment levels (ALs) were measured and bleeding on probing (BOP) was recorded. Results: At 6-month evaluation, all groups showed an improvement in clinical parameters. No statistically significant differences in any of the investigated parameters could be observed between the Vector group and the hand scaling groups, or when comparing the results of the two different operators. Conclusion: This study demonstrates that Vector™ treatment with polishing fluid was able to reduce pocket depths and the prevalence of BOP and improve clinical AL in a similar way as scaling with curettes.

The purpose of this study was to compare a high-speed handpiece to an ultrasonic device regarding the time taken for cavity preparation in bovine incisor teeth (n = 12), and to evaluate microleakage after the restorations. Two cylindrical cavities each were prepared on the labial surfaces of 12 teeth. One of them was made with a diamond tip in group 1 (G(1) = 12) coupled with a high-speed handpiece, and the other with a chemical vapor deposition (CVD) tip in group 2 (G(2) = 12) coupled with an ultra-sound device (n = 24). The time taken for each preparation was measured with a stopwatch. The cavities were treated with adhesive (Scotchbond Multipurpose, 3M), restored with composite (Filtek Z250, 3M), finished and polished, and then the prepared teeth were immersed in a 50% silver nitrate solution. The samples were cut in the mesio-distal direction and evaluated for microleakage. Data were analyzed using the Wilcoxon test (P < 0.01). The results revealed that the time taken to prepare cavities was 7.9 times shorter in G(1). There was no microleakage in 100% of the samples indicated by the absence of dye penetration in G(1), and 46% in G(2). It was concluded that the performance of the high-speed handpiece was better than that of the oscillatory system, in terms of both the time taken for preparation and the microleakage.

The purpose of this study was to determine the elastic modulus of enamel during bleaching procedure with the use of an ultrasonic device. Enamel sections were obtained from freshly extracted bovine incisors. Specimens were exposed to 10% carbamide peroxide for two hours, followed by an application of a fluoride-containing toothpaste for five minutes and stored in artificial saliva (pH 7.0). An ultrasonic device was used to measure the sound velocities of longitudinal and shear waves as well as elastic modulus. The mean elastic modulus of bleached enamel decreased with time, from 15.5 GPa to 10.1 GPa. Conversely, the elastic modulus of bleached enamel followed by application of a fluoride-containing toothpaste increased with time, from 15.2 GPa to 20.2 GPa. Results of this study indicated that a decrease in elastic modulus associated with bleaching occurred, and that fluoride-containing toothpaste reversed this effect.

To evaluate the clinical treatment effects of a glycine powder air-polishing or ultrasonic device on peri-implant mucositis.Thirty-seven patients with one implant diagnosed with peri-implant mucositis (probing depth ≥4 mm (0.2N) and bleeding on probing (BOP) (primary outcome)) were randomly assigned to treatment with either glycine powder air-polishing (GPAP) or ultrasonic (US) debridement. Treatment was performed at baseline and at 3 and 6 months. Professional supra gingival cleaning was performed at 9 and 12 months. Oral hygiene instructions were reinforced at each visit.At 12 months there was a statistically significant reduction in mean plaque score, bleeding on probing and number of periodontal pockets ≥4 mm within the treatment groups compared to baseline. The percentages of diseased sites were significantly reduced for both groups.Treatment with a glycine powder air-polishing or an ultrasonic device is effective in non-surgical treatment of peri-implant mucositis.

In April 2001, a 9-year-old child was attacked and killed by dingoes on Fraser Island, Australia. The Dingo Management Strategy formulated in response to this incident proposed ultrasonic deterrents as one of a number of non-lethal management techniques requiring further investigation. In this paper, we describe a preliminary examination of an ultrasonic deterrent to dingoes using four captive animals as test subjects. Although replication was minimal, the use of a simple experimental design, in combination with a flexible analytical technique, sufficiently demonstrated that the unit tested produced no measurable effect as a deterrent to test subjects.

Brian D Bertke,1 Patrick J Scoggins,1 Alissa L Welling,1 Tamara V Widenhouse,1 Chaoyang Chen,2 Srinivasu Kallakuri,2 John M Cavanaugh,2 Jeffrey W Clymer,1 Joseph F Amaral1 1Ethicon, Inc., Cincinnati, OH, USA; 2Spine Research Laboratory, Bioengineering Center, Wayne State University, Detroit, MI, USA Background: A new ultrasonic device, Harmonic Focus®+, has been developed that is smaller and delivers energy more efficiently than its predecessor via the inclusion of Adaptive Tissue Technology. This study was undertaken to compare its dissection capabilities to an advanced bipolar electrosurgery device in benchtop and preclinical evaluations. Methods: In ex vivo testing, Focus+ and LigaSure™ Small Jaw were evaluated for physical dimensions, device and tissue temperature after repeated applications to porcine jejunum, and burst pressure of vessel seals, transection time, and tissue sticking in 3–5 mm porcine carotid arteries. In in vivo testing, the devices were tested on intact porcine carotid arteries for thermal damage via collagen denaturation and in muscle incisions near rat sciatic nerve for acute inflammation via hematoxylin and eosin and for impaired axonal transport via β-APP. Results: Focus+ was smaller than the Small Jaw in width and height, yet it had a longer active blade and larger jaw aperture. Device temperatures were not different after application, but thermal spread (tissue temperature above 50°C) was 78% greater for Small Jaw (9.6 mm) than for Focus+ (5.4 mm). Burst pressures of sealed vessels were not significantly different between the devices: 900 (±466) mmHg for Focus+ versus 974 (±500) mmHg for Small Jaw. Small Jaw had a shorter individual transection time (5.0 seconds compared to 6.3 seconds for Focus+), whereas Focus+ had 70% less tissue sticking. Thermal damage, neural inflammation, and impaired axonal transport were all significantly lower for Focus+ compared to Small Jaw, by 19%, 57%, and 50%, respectively. Conclusion: With the addition of Adaptive Tissue Technology, Harmonic Focus+ builds upon the manifold advantages of ultrasonic devices in procedures requiring meticulous dissecting capability. Improvements in energy sensing and controlled delivery produce lower tissue temperatures and less thermal damage, especially critical when working near nerves. Focus+ produces vessel seal strengths equivalent to advanced bipolar devices and, although individual device activations are longer, the reduction in tissue sticking is expected to materially lessen operative time in clinical practice. Keywords: Harmonic, Focus, precision, vessel sealing, thyroidectomy, dissection

A needle biopsy is a kind of the inspection to extract the muscles under the skin with a needle, the inspection method accelerated the research on muscle characteristic and a sick of muscle. Current needle can extract only the muscular tissue of a limited structure. Based on the above background, we work in research and development of novel needle biopsy system in order to extract muscle tissue with form of fiber. The system consists of an ultrasonic device, an angular adjustment implement, and a needle. The needle has curved shape so penetrates from skin surface perpendicularly and takes route parallel to bone in muscle tissue. When the needle is inserting in muscle, pressure are given for muscle tissue. And then reaction force was given to the tip of needle. We designed prototype of the needle's tip using reaction force to close. We report in this paper developing needle biopsy system and designing tip of needle.

The speed of sound u and density ρ for the binary mixture hexane + hexadecane has been measured as a function of composition and temperature along the saturation line between 293.15 K and 373.15 K. The speed of sound was measured by a pulse-phase echo ultrasonic device at a frequency of (1 to 5) MHz with an uncertainty of ±0.1%. The density was measured by an Ostwald−Sprengel-type pycnometer with an uncertainty of ±3 × 10-5 g·cm-3. The experimental results were used to calculate deviations of the speed of sound Δu, excess molar volume VE, and isentropic compressibility kS. The values Δu and VE were fitted by the Redlich−Kister equation.

The aim of the present study was to investigate the effect of manual and ultrasonic insertion of standardized class I inlays (Cerana) using three composite resin materials of different viscosity (Tetric Flow, Tetric, and Tetric Ceram) on time to seat inlays, film thickness, and filler distribution within the materials.In a preliminary test, mean loads for manual and ultrasonic insertion were measured using the high viscosity composite resin material (Tetric Ceram). These loads were then applied with all composite resin materials to evaluate the times required to seat the inlays. In addition, film thickness was assessed using scanning electron microscopy, and filler distribution (wt% silicon, barium, ytterbium) was monitored using energy-dispersive spectroscopy.Ultrasonic insertion significantly reduced mean load applied to seat inlays (6.4+/-1.4 N; mean+/-SD) as compared to manual insertion (18.9+/-3.1 N; p0.001). Using an ultrasonic device, times for insertion values were significantly lower in the high and medium viscosity composite resin material groups compared to manual insertion (p0.05). The widest film thickness was recorded for the high viscosity composite resin material in combination with manual insertion (p0.05). However, when ultrasound was applied, there was no difference in film thickness between the three materials at any levels. Furthermore, the analysis of filler distribution revealed no significant differences between groups.Highly filled viscous composite resin materials may be used in combination with the ultrasonic insertion technique without untoward effects on film thickness or filler distribution.

I thank all who have made it possible for me to write this history by giving me an opportunity to be a part of it. I also thank Ann Polin, Carolyn Coffin, and Jean Lea Spitz for assistance. Abbreviations ACR, American College of Radiology; AIUM, American Institute of Ultrasound in Medicine; AMA, American Medical Association; ARDMS, American Registry of Diagnostic Medical Sonographers; ASE, American Society of Echocardiography; ASUTS, American Society of Ultrasound Technical Specialists; CAHEA, Committee on Allied Health Education and Accreditation; JRCDMS, Joint Review Committee on Education in Diagnostic Medical Sonography; SDMS, Society of Diagnostic Medical Sonographers/Society of Diagnostic Medical Sonography; SVT, Society of Vascular Technology; WFUMB, World Federation for Ultrasound in Medicine and Biology ne of the most important questions to be answered when writing a history of the profession is where to begin. Pythagoras certainly played a role when he observed the relationship between sound pitch and frequency, but he did not make this observation related to medicine. John William Strutt, the third Baron Rayleigh, one of the few members of nobility to also be an outstanding scientist and 1904 Nobel Prize winner, published among many works the Theory of Sound. Christian Doppler lent his name to the Doppler effect, something we use every day when performing sonographic procedures. But many think that the true conception of ultrasound occurred in 1880 with the discovery of piezoelectricity by the French physicist Pierre Curie. Along with his brother Jacques, he performed experiments that showed that when certain crystals are subjected to an electrical field, they can be made to expand and contract, converting electrical into mechanical energy. These piezoelectric crystals can then act as both transmitters and receivers of sound. Since the early days of medicine, there has been a great desire to “see” inside the body. This is what drove Roentgen to develop x rays in 1895, Helmholtz the ophthalmoscope in 1851, Garcia the laryngoscope in 1854, and Nitze the cystoscope in 1876. Sound was first applied to the human body through auscultation in 1761 and the stethoscope in 1819, and interpreting these sounds required imagination, as did interpreting the early sonographic images. In the beginning, Doppler ultrasound was also strictly an analysis of audible sound.1,2 The use of ultrasound in medicine is similar to many technologic advances that owe their fame to war. The French government asked Paul Langevin, PhD, to develop a device capable of detecting submerged enemy submarines. The device he developed used the piezoelectric effect, which he had learned as a student with the Curies. He used quartz crystals and vacuum tube amplifiers, which were also used with early medical ultrasonic transducers. This was considered the first ultrasonic device. This research was not completed in time to be applied to the war effort. However, it did form the basis of sound navigation ranging (SONAR) detection, which was further developed during the Second World War.1,2

Background In an in vitro study, the surface wear on cervical restorations and adjacent enamel and root cementum caused by different tooth-cleaning methods in simulated long-term therapy was investigated. Methods Cervical restorations of amalgam (Oralloy), modified composite resin (Dyract), glass-ionomer cement (ChemFill Superior), and composite (Tetric) were instrumented by POL (polishing), CUR+POL (curette and polishing), US+POL (ultrasonic device with polishing) and the polishing agents Cleanic and Proxyt in a computer-controlled test bench. Treatment time corresponding to a real-time period of 5 or 10 years. Substance loss from instrumented surfaces was measured with a digital gauge. A three-way anova was used in the statistical evaluation. Results The results showed that POL led to slight substance loss, which was greater using Cleanic (27 microm) than Proxyt (5 microm). CUR+POL produced a significantly greater substance loss than did US+POL, with 186 microm versus 35 microm on glass-ionomer cement, respectively, and 123 microm versus 18 microm, respectively, on root cementum, followed by composite (111 microm versus 27 microm, respectively), polyacid modified composite resin/compomer (89 microm versus 36 microm), amalgam (75 microm versus 19 microm), and enamel (32 microm versus 23 microm). Conclusions As opposed to the use of US+POL or POL, substance loss on cervical restorations and especially root cementum must be expected to result from tooth-cleaning during long-term maintenance treatment using CUR+POL.

The purpose of this study was to determine the elastic moduli of the components at resin-dentin interface with the use of an ultrasonic device. Dentin plates were obtained from freshly extracted bovine incisors with a shape in rectangular form. Resin composites and bonding agents were polymerized and trimmed in the same shape as the dentin specimens. The ultrasonic equipment employed in this study was comprised of a Pulser-Receiver, transducers, and an oscilloscope. Each elastic modulus was determined by measuring the longitudinal and shear wave sound velocities. The mean elastic modulus of mineralized dentin was 17.4 GPa, while that of demineralized dentin was 1.4 GPa. When the demineralized dentin was immersed in bonding agents, the elastic modulus changed to 3.7-4.7 GPa, and these values were significantly higher than those of demineralized dentin. A gradient in elastic modulus was detected as the analysis shifted from the dentin side to the resin composite.

In this study we used a Doppler ultrasonic device, in combination with a sonographic contrast medium, to test whether free-living bearded seal (Erignathus barbatus) pups have a closed (anatomically or functionally) foramen ovale. A total of 17 examinations were performed on 12 individual pups with a body mass range of 29-103 kg (0-21 days old). These examinations showed that young bearded seal pups dive with a patent foramen ovale (PFO), and that this structure starts to close, at least functionally, during the 2nd week of life. The wide range in the timing of closure (one animal 21 days old still had a PFO) indicates that a closed foramen ovale is not crucial for the diving that these seals perform at this age. The primary function of diving during the 1st week of life is to avoid surface predation and only moderate diving ability is sufficient to achieve this goal. However, some of the diving performed by bearded seal pups with a PFO would likely be sufficient to create intravenous bubble formation during breath-hold diving in humans. Special adaptations in the seals, such as collapsible lungs and diving with minimal lung air volume, probably prevent this from happening.