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Your search keyword '"Tyrosine -- Genetic aspects"' showing total 232 results
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232 results on '"Tyrosine -- Genetic aspects"'

201. New research on proteomics from New York Medical College summarized

Subjects
New York Medical College, Genetic aspects, Universities and colleges -- Genetic aspects, Tyrosine -- Genetic aspects, Proteomics -- Genetic aspects, Messenger RNA -- Genetic aspects
Abstract

Scientists discuss in 'Differential regulation of the tyrosine hydroxylase and enkephalin neuropeptide transmitter genes in rat PC12 cells by short chain fatty acids: concentration-dependent effects on transcription and RNA stability' [...] more...

Published
2007

202. Scientists at University of Chicago publish new data on cancer

Subjects
University of Chicago, Genetic aspects, Universities and colleges -- Genetic aspects, Cancer -- Genetic aspects, Tyrosine -- Genetic aspects, Scientists -- Genetic aspects
Abstract

Researchers detail in 'Tyrosine kinase mutations in human cancer,' new data in cancer. 'A subset of tyrosine kinases are activated by mutations which contribute to the malignant transformation, growth, and [...] more...

Published
2007

203. Investigators at School of Medicine release new data on leukemia

Subjects
Drug therapy, Genetic aspects, Protein binding -- Genetic aspects, Biological response modifiers -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Interferon -- Genetic aspects, Leukemia -- Drug therapy -- Genetic aspects
Abstract

Researchers detail in 'Leukemia-associated, constitutively active mutants of SHP2 protein tyrosine phosphatase inhibit NF1 transcriptional activation by the interferon consensus sequence binding protein,' new data in leukemia. According to recent [...] more...

Published
2007

204. Gastric carcinogenesis linked to Helicobacter pylori CagA infection

Subjects
Genetic aspects, Stomach cancer -- Genetic aspects, Adenocarcinoma -- Genetic aspects, Cancer genetics -- Genetic aspects, Communicable diseases -- Genetic aspects, Tyrosine -- Genetic aspects, Infection -- Genetic aspects, Helicobacter pylori -- Genetic aspects, Carcinogenesis -- Genetic aspects, Cancer -- Genetic aspects
Abstract

Gastric carcinogenesis could be linked to Helicobacter pylori CagA infection. According to a study from Japan, 'Infection with cagA-positive Helicobacter pylori (H. pylori) is associated with the development of gastric [...] more...

Published
2006

205. Metaplastic breast cancers with select gene profiles may respond to tyrosine kinase inhibitors

Subjects
Genetic aspects, Cancer treatment -- Genetic aspects, Genetic research -- Genetic aspects, Cancer genetics -- Genetic aspects, Tyrosine -- Genetic aspects, Epidermal growth factors -- Genetic aspects, Breast cancer -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Phenols -- Genetic aspects, Cancer -- Genetic aspects -- Care and treatment, Epidermal growth factor -- Genetic aspects
Abstract

Metaplastic breast cancers with select gene profiles may respond to tyrosine kinase inhibitors. 'Metaplastic breast carcinomas are reported to harbour epidermal growth factor receptor (EGFR) overexpression in up to 80% [...] more...

Published
2006

206. Protein tyrosine phosphatase nonreceptor type 22 gene 1858T variant is rare in Asian Indians

Subjects
Genetic aspects, Diabetes mellitus -- Genetic aspects, Genetic research -- Genetic aspects, Rheumatoid factor -- Genetic aspects, Tyrosine -- Genetic aspects, Medical research -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Medicine, Experimental -- Genetic aspects, Diabetes -- Genetic aspects, Phenols -- Genetic aspects
Abstract

Protein tyrosine phosphatase nonreceptor type 22 gene 1858T variant is rare in Asian Indians. 'Recently, a gain of function variant C1858T of the lymphoid-specific protein tyrosine phosphatase nonreceptor (LYP, PTPN22) [...] more...

Published
2006

207. Fms-like tyrosine kinase 3/ITD is a relevant marker for acute myeloid leukemia prognosis

Subjects
Genetic aspects, Prognosis, Tyrosine -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Acute myelocytic leukemia -- Prognosis -- Genetic aspects, Phenols -- Genetic aspects
Abstract

Fms-like tyrosine kinase 3/ITD is a relevant marker for acute myeloid leukemia prognosis. According to recent research from the Netherlands, 'In acute myeloid leukemia (AML), activating mutations in the fms-like [...] more...

Published
2006

208. EGFR mutations in lung cancer patients may be ethnocentric

Subjects
Diseases, Care and treatment, Genetic aspects, Genetic research -- Genetic aspects, Cancer genetics -- Care and treatment -- Genetic aspects, Tyrosine -- Genetic aspects, Medical research -- Genetic aspects, Epidermal growth factors -- Genetic aspects, Cancer patients -- Care and treatment -- Genetic aspects, Non-small cell lung cancer -- Care and treatment -- Genetic aspects, Medicine, Experimental -- Genetic aspects, Cancer -- Genetic aspects, Lung cancer, Non-small cell -- Care and treatment -- Genetic aspects, Epidermal growth factor -- Genetic aspects
Abstract

Epidermal growth factor receptor (EGFR) mutations in lung cancer patients may be ethnocentric. According to recent research from Greece, 'Somatic tyrosine kinase (TK) domain mutations of the (EGFR) gene are [...] more...

Published
2006

209. Lymphoid tyrosine phosphatase Arg620Trp variant regulates progression to type 1 diabetes

Subjects
Development and progression, Genetic aspects, Diabetes mellitus -- Development and progression -- Genetic aspects, Autoimmunity -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Type 1 diabetes -- Development and progression -- Genetic aspects, Diabetes -- Development and progression -- Genetic aspects, Phenols -- Genetic aspects
Abstract

Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes. According to recent research published in the journal Diabetologia, 'We analysed the contribution of the [...] more...

Published
2006

210. Protein tyrosine phosphatase-N1 variants are linked to coronary calcified plaque in diabetes

Subjects
Wake Forest University, Genetic aspects, Diabetes research -- Genetic aspects, Diabetes mellitus -- Genetic aspects, Atherosclerosis -- Genetic aspects, Tyrosine -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Genetic aspects -- Research, Phenols -- Genetic aspects
Abstract

Protein tyrosine phosphatase-N1 polymorphisms are linked to coronary calcified plaque in the Diabetes Heart Study. 'Individuals with type 2 diabetes are at increased risk of cardiovascular disease (CVD) mortality and [...] more...

Published
2006

211. Dasatinib may affect neoplasms associated with gain-of-function KIT mutations

Subjects
Genetic aspects, Cancer treatment -- Genetic aspects, Drugs -- Genetic aspects, Imatinib mesylate -- Genetic aspects, Cancer research -- Genetic aspects, Tyrosine -- Genetic aspects, Tumors -- Genetic aspects, Oncology, Experimental -- Genetic aspects, Cancer -- Care and treatment -- Research
Abstract

Researchers suggest that dasatinib may affect neoplasms which are associated with gain-of-function KIT mutations. 'Activating mutations of the activation loop of KIT are associated with certain human neoplasms, including the [...] more...

Published
2006

212. Shp2 tyrosine phosphatase overexpression implicated in leukemogenesis

Subjects
Genetic aspects, Cancer genetics -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Leukemia -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Phenols -- Genetic aspects, Cancer -- Genetic aspects
Abstract

Shp2 tyrosine phosphatase overexpression was implicated in the leukemogenesis in adult human leukemia. According to a study from the People's Republic of China, 'Shp2 tyrosine phosphatase plays a critical role [...] more...

Published
2006

213. EGFR tyrosine kinase domain mutations predict pathogenesis of lung cancer

Subjects
Genetic aspects, Lung cancer -- Genetic aspects, Cancer genetics -- Genetic aspects, Cancer research -- Genetic aspects, Tyrosine -- Genetic aspects, DNA -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Oncology, Experimental -- Genetic aspects, Phenols -- Genetic aspects, Cancer -- Genetic aspects -- Research
Abstract

The occurrence of EGFR tyrosine kinase domain mutations can be used to predict the pathogenesis of lung cancer. In a recent article published in the journal Cancer Research, scientists in [...]

Published
2005

214. Scientists identify key genetic mutations in brain tumors

Subjects
Genetic aspects, Brain -- Genetic aspects, Genetic research -- Genetic aspects, Drugs -- Genetic aspects, Cancer research -- Genetic aspects, Gene mutation -- Genetic aspects, Tyrosine -- Genetic aspects, DNA -- Genetic aspects, Brain tumors -- Genetic aspects, Scientists -- Genetic aspects, Gene mutations -- Genetic aspects, Oncology, Experimental -- Genetic aspects, Cancer -- Research
Abstract

Scientists from J. Craig Venter Institute, Ludwig Institute for Cancer Research, and The Johns Hopkins University School of Medicine identified three novel mutations in two receptor tyrosine kinases in glioblastoma [...] more...

Published
2005

215. Tyrosine kinase inhibitors modify the invasive phenotype of prostate cancer

Subjects
Genetic aspects, Tyrosine -- Genetic aspects, Proteases -- Genetic aspects, Phenols (Class of compounds), Phenols
Abstract

Tyrosine kinase inhibitors modify the invasive phenotype of prostate cancer. According to recent research from Norway, 'urokinase-type plasminogen activator (uPA) seems to be an important protease in prostate cancer invasion, [...] more...

Published
2005

216. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic research -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols -- Genetic aspects, Tyrosine -- Genetic aspects, Diabetes -- Research, Diabetes -- Genetic aspects, Health, Pharmaceuticals and cosmetics industries
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

217. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Genetic research -- Genetic aspects, Tyrosine -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Research, Phenols -- Genetic aspects
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

218. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Genetic research -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Phenols -- Genetic aspects, Diabetes -- Research
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

219. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Genetic research -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Research, Phenols -- Genetic aspects
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

220. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Genetic research -- Genetic aspects, Tyrosine -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Research, Phenols -- Genetic aspects
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

221. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Genetic research -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Research, Phenols -- Genetic aspects
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

222. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Genetic research -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Research, Phenols -- Genetic aspects
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

223. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Genetic research -- Genetic aspects, Tyrosine -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Research, Phenols -- Genetic aspects
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

224. Protein tyrosine phosphatase 1B gene not associated with type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Genetic research -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Research, Phenols -- Genetic aspects
Abstract

Testing of 7,883 people did not reveal any significant association between the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 [...] more...

Published
2005

225. Benign skin tumors analyzed, role of tyrosine kinase receptor mutations shown

Subjects
Genetic aspects, Skin cancer -- Genetic aspects, Gene mutation -- Genetic aspects, Tyrosine -- Genetic aspects, Tumors -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Gene mutations -- Genetic aspects, Phenols -- Genetic aspects
Abstract

According to recent research from France published in the journal Human Molecular Genetics, activating mutations of the tyrosine kinase receptor fibroblast growth factor receptor 3 (FGFR3) are associated with benign [...] more...

Published
2005

226. Recent findings in diabetes pathogenesis provide new insights

Subjects
Genetic aspects, Diabetes mellitus -- Genetic aspects, Tyrosine -- Genetic aspects, Medical research -- Genetic aspects, Phosphatases -- Genetic aspects, Medicine, Experimental -- Genetic aspects, Diabetes -- Genetic aspects
Abstract

Diabetes pathogenesis research advances have been reported from the United States, Germany and Israel. Study 1: The C allele of PTPN22 is linked to autoimmunity susceptibility. According to published research [...] more...

Published
2005

227. Reports describe recent advances in leukemia research

Subjects
Genetic aspects, Cancer genetics -- Genetic aspects, Drugs -- Genetic aspects, Cancer research -- Genetic aspects, Gene mutation -- Genetic aspects, Tyrosine -- Genetic aspects, Gene expression -- Genetic aspects, Gene mutations -- Genetic aspects, Oncology, Experimental -- Genetic aspects, Cancer -- Genetic aspects -- Research
Abstract

Data on leukemia are outlined in reports from Germany, Switzerland and France. Study 1: Distinct gene expression patterns might have been linked to FLT3- and NRAS-activating mutations in acute myeloid [...] more...

Published
2005

228. Protein tyrosine phosphatase polymorphisms linked to glucose homeostasis

Subjects
Genetic aspects, Diabetes mellitus -- Genetic aspects, Homeostasis -- Genetic aspects, Glucose -- Genetic aspects, Tyrosine -- Genetic aspects, Insulin resistance -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Proteins -- Genetic aspects, Dextrose -- Genetic aspects, Diabetes -- Genetic aspects, Phenols -- Genetic aspects
Abstract

Protein tyrosine phosphatase 1B gene polymorphisms are associated with measures of glucose homeostasis in Hispanic Americans. 'Protein tyrosine phosphatase (PTP)-1B, encoded by the PTPN1 gene, catalyzes the dephosphorylation of proteins [...] more...

Published
2005

229. Lymphoid tyrosine phosphatase locus associated with type 1 diabetes

Subjects
Genetic aspects, Diabetes mellitus -- Genetic aspects, Tyrosine -- Genetic aspects, Medical research -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Type 1 diabetes -- Genetic aspects, Medicine, Experimental -- Genetic aspects, Diabetes -- Genetic aspects, Phenols -- Genetic aspects
Abstract

The lymphoid tyrosine phosphatase locus (LYP/PTPN22) is associated with type 1 diabetes and plays a role as a general autoimmunity locus. According to recent research published in the journal Diabetes, [...] more...

Published
2005

230. Protein tyrosine phosphatase 1B gene polymorphisms linked to type 2 diabetes

Subjects
Genetic aspects, Diabetes research -- Genetic aspects, Diabetes mellitus -- Genetic aspects, Genetic research -- Genetic aspects, Type 2 diabetes -- Genetic aspects, Tyrosine -- Genetic aspects, Phosphatases -- Genetic aspects, Phenols (Class of compounds) -- Genetic aspects, Diabetes -- Genetic aspects -- Research, Phenols -- Genetic aspects
Abstract

Protein tyrosine phosphatase 1B gene polymorphisms are associated with type 2 diabetes. 'The PTPN1 gene codes for protein tyrosine phosphatase 1B (PTP1B) (EC 3.1.3.48), which negatively regulates insulin signaling by [...] more...

Published
2005

231. Tyrosine Nitration: Common Denominator in ALS?

Subjects
Tyrosine -- Genetic aspects, Nitration -- Genetic aspects, Amyotrophic lateral sclerosis -- Genetic aspects, Phenols -- Genetic aspects, Health, Psychology and mental health
Abstract

Tyrosine Nitration: Common Denominator in ALS? ABSTRACT & COMMENTARY Source: Beal MF, et al. Increased 3-nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis. Ann Neurol 1997;42:644-654. Amyotrophic lateral sclerosis [...] more...

Published
1998

232. New lung cancer therapy research from Seoul National University, Cancer Research Institute discussed

Author

Hasty, Susan

Subjects
Genetic aspects, Lapatinib, Cancer treatment, Cetuximab, Cancer research -- Genetic aspects, Tyrosine -- Genetic aspects, Epidermal growth factors -- Genetic aspects, Non-small cell lung cancer -- Genetic aspects, Oncology, Experimental -- Genetic aspects, Cancer -- Care and treatment -- Research, Lung cancer, Non-small cell -- Genetic aspects, Epidermal growth factor -- Genetic aspects
Abstract

2008 APR 28 -- (NewsRx.com)--Research findings, 'Combined lapatinib and cetuximab enhance cytotoxicity against gefitinib-resistant lung cancer cells,' are discussed in a new report. According to recent research published in the [...] more...

Published
2008

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