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2,665 results on '"Tada, K."'

208. THE COMPARISON OF FORMATION OF PHOTO-INDUCED GRATING IN AZO-CARBAZOLE DYE DOPED POLYMER BY LINEARLY AND CIRCULARLY POLARIZED LASER IRRADIATION.

Author

Tada, K., Imai, T., and Kawabe, Y.

Subjects
CARBAZOLE, DYES & dyeing, FIBER gratings, LASER beams, HOLOGRAPHY
Abstract

Two types of azo-carbazole dyes embedded in a polymer matrix were applied as media for polarization (vector) grating inscription. Highly concentrated (30%) thick devices were formed by pressing molten mixture of the dye and polymer at high temperature. Gratings were inscribed with interfering excitation beams under several types of polarization configurations, and their performance and temporal evolution were monitored with non-degenerate four-wave mixing (FWM) experiment. Results gave dependence of performace on the material and polarization configuration. Particularly, 3-[(4-Cyanophenyl)azo]-9H-carbazole-9-ethanol (CACzEtOH) showed the highest diffraction up to 30% and long persistency of the grating, indicating that azocarbazole dyes could be good candidates for applications to rewritable holography. [ABSTRACT FROM AUTHOR]

Published
2014

209. UPDATABLE 3D HOLOGRAPHIC DISPLAY SYSTEM: S-INNOVATION PROJECT'S STRATEGY AND FUTURE PERSPECTIVES.

Author

Tsutsumi, N., Kinashi, K., Kawabe, Y., Tada, K., Fukuzawa, K., Sasaki, T., Naka, Y., Sassa, T., and Fujihara, T.

Subjects
HOLOGRAPHIC displays, FERROELECTRIC liquid crystals, TRIPHENYLAMINE, TECHNOLOGICAL innovations, DIFFRACTION gratings
Abstract

We present a strategy to achieve an updatable three-dimensional (3D) holographic display system currently developed by our S-innovation project. Photorefractive polymers are promising materials for an updatable 3D holographic display and imaging. Triphenylamine-based photorefractive (PR) polymer composites have a high potential for a holographic display device with the fast response time of 2.2 ms and the high diffraction efficiency of 59 % under an applied field of 60 V µm-1. A PR ferroelectric liquid crystal system gave a faster response time of 900 µs and an extremely large optical gain up to 1200 cm-1. In addition to these advanced PR composites, PR-like monolithic compound with no-bias field gave great potentials for a 3D holographic diffraction application. Further a molecular designing of PR composites promises an updatable full-color 3D holographic display system. [ABSTRACT FROM AUTHOR]

Published
2014

215. Addiction to the IGF2-ID1-IGF2 circuit for maintenance of the breast cancer stem-like cells

Author

Tominaga, K, Shimamura, T, Kimura, N, Murayama, T, Matsubara, D, Kanauchi, H, Niida, A, Shimizu, S, Nishioka, K, Tsuji, E-i, Yano, M, Sugano, S, Shimono, Y, Ishii, H, Saya, H, Mori, M, Akashi, K, Tada, K-i, Ogawa, T, Tojo, A, Miyano, S, and Gotoh, N

Abstract

The transcription factor nuclear factor-κB (NF-κB) has important roles for tumorigenesis, but how it regulates cancer stem cells (CSCs) remains largely unclear. We identified insulin-like growth factor 2 (IGF2) is a key target of NF-κB activated by HER2/HER3 signaling to form tumor spheres in breast cancer cells. The IGF2 receptor, IGF1 R, was expressed at high levels in CSC-enriched populations in primary breast cancer cells. Moreover, IGF2-PI3K (IGF2-phosphatidyl inositol 3 kinase) signaling induced expression of a stemness transcription factor, inhibitor of DNA-binding 1 (ID1), and IGF2 itself. ID1 knockdown greatly reduced IGF2 expression, and tumor sphere formation. Finally, treatment with anti-IGF1/2 antibodies blocked tumorigenesis derived from the IGF1RhighCSC-enriched population in a patient-derived xenograft model. Thus, NF-κB may trigger IGF2-ID1-IGF2-positive feedback circuits that allow cancer stem-like cells to appear. Then, they may become addicted to the circuits. As the circuits are the Achilles’ heels of CSCs, it will be critical to break them for eradication of CSCs.

Published
2017
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233. Cladribine (2CdA) Is Comparable To Fludarabine In A Busulfan-Based Reduced- Intensity Regimen

Author

Yakushijin, K., primary, Fukuda, T., additional, Asakura, Y., additional, Kurosawa, S., additional, Hiramoto, N., additional, Tada, K., additional, Nishinohara, M., additional, Maeda, T., additional, Hagiwara, A., additional, Ueno, N., additional, Kamiyama, Y., additional, Mori, M., additional, Kim, S.-W., additional, Mori, S., additional, Tanosaki, R., additional, Heike, Y., additional, and Takaue, Y., additional

Published
2010
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243. Serial magnetic resonance imaging studies in a case of late onset globoid cell leukodystrophy

Author

Ono J, Koji Inui, Taniike M, Tada K, Shintaro Okada, and Hiroko Tsukamoto

Subjects
Male, Pathology, medicine.medical_specialty, Spastic gait, Biopsy, Late onset, Sural nerve, White matter, Sural Nerve, Galactosylceramidase, Medicine, Humans, medicine.diagnostic_test, business.industry, Leukodystrophy, Brain, Magnetic resonance imaging, General Medicine, medicine.disease, Magnetic Resonance Imaging, Leukodystrophy, Globoid Cell, medicine.anatomical_structure, Child, Preschool, Muscle Tonus, Pediatrics, Perinatology and Child Health, Krabbe disease, Neurology (clinical), business, Tomography, X-Ray Computed
Abstract

The late onset type of globoid cell leukodystrophy (GLD) is a rare disorder and only three magnetic resonance imaging (MR) studies have been reported for this disease. We report a sporadic case of late onset GLD. The illness started at the age of 3 years and 8 months with spastic gait. He became bedridden at the age of 4 years and 7 months. The diagnosis was made by deficient activity of galactosylceramidase in lymphocytes, and the biochemical and morphological examinations of the biopsied sural nerve were also conducted. Computed tomography (CT) and MR study revealed that the degenerative change of the white matter was initially recognized in the occipital and parietal lobes and then extended forward. Literature of the CT or MR findings of GLD is also reviewed.

Published
1992

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