201. [Nuclear spin tomographic diagnosis of brain tumors using the contrast medium gadolinium-DTPA].
- Author
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Schörner W, Felix R, Claussen C, Fiegler W, Kazner E, Speck U, and Niendorf HP
- Subjects
- Adult, Aged, Brain diagnostic imaging, Brain Neoplasms secondary, Female, Humans, Male, Middle Aged, Pilot Projects, Tomography, X-Ray Computed, Brain Neoplasms diagnosis, Gadolinium, Magnetic Resonance Spectroscopy, Pentetic Acid
- Abstract
This study examines the effect of the NMR contrast medium gadolinium-DTPA on image contrast in cerebral tumours. Sixteen patients with space-occupying cerebral lesions were examined on a 0.35 Tesla superconducting scanner, using a T1-weighted spinecho sequence prior to and after the intravenous application of gadolinium-DTPA. In 8 patients T2-weighted spinecho-sequences were obtained before the administration of contrast. The tomograms were evaluated visually and according to quantitative criteria. The use of gadolinium-DTPA helps to evaluate the blood-brain barrier and improves diagnosis by differentiating tumour tissue from edema and from normal brain tissue.
- Published
- 1984
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