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16,744 results on '"Sapienza, A."'

204. Modulatory actions of Echinococcus granulosus antigen B on macrophage inflammatory activation

Author

Ana Maite Folle, Sofía Lagos Magallanes, Martín Fló, Romina Alvez-Rosado, Federico Carrión, Cecilia Vallejo, David Watson, Josep Julve, Gualberto González-Sapienza, Otto Pristch, Andrés González-Techera, and Ana María Ferreira

Subjects
cestodes, Echinococcus granulosus, HLBP family, lipoprotein, antigen B, immunomodulation, Microbiology, QR1-502
Abstract

Cestodes use own lipid-binding proteins to capture and transport hydrophobic ligands, including lipids that they cannot synthesise as fatty acids and cholesterol. In E. granulosus s.l., one of these lipoproteins is antigen B (EgAgB), codified by a multigenic and polymorphic family that gives rise to five gene products (EgAgB8/1-5 subunits) assembled as a 230 kDa macromolecule. EgAgB has a diagnostic value for cystic echinococcosis, but its putative role in the immunobiology of this infection is still poorly understood. Accumulating research suggests that EgAgB has immunomodulatory properties, but previous studies employed denatured antigen preparations that might exert different effects than the native form, thereby limiting data interpretation. This work analysed the modulatory actions on macrophages of native EgAgB (nEgAgB) and the recombinant form of EgAg8/1, which is the most abundant subunit in the larva and was expressed in insect S2 cells (rEgAgB8/1). Both EgAgB preparations were purified to homogeneity by immunoaffinity chromatography using a novel nanobody anti-EgAgB8/1. nEgAgB and rEgAgB8/1 exhibited differences in size and lipid composition. The rEgAgB8/1 generates mildly larger lipoproteins with a less diverse lipid composition than nEgAgB. Assays using human and murine macrophages showed that both nEgAgB and rEgAgB8/1 interfered with in vitro LPS-driven macrophage activation, decreasing cytokine (IL-1β, IL-6, IL-12p40, IFN-β) secretion and ·NO generation. Furthermore, nEgAgB and rEgAgB8/1 modulated in vivo LPS-induced cytokine production (IL-6, IL-10) and activation of large (measured as MHC-II level) and small (measured as CD86 and CD40 levels) macrophages in the peritoneum, although rEgAgB8/1 effects were less robust. Overall, this work reinforced the notion that EgAgB is an immunomodulatory component of E. granulosus s.l. Although nEgAgB lipid’s effects cannot be ruled out, our data suggest that the EgAgB8/1 subunit contributes to EgAgB´s ability to regulate the inflammatory activation of macrophages.

Published
2024
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205. Ultrafine particulate matter pollution and dysfunction of endoplasmic reticulum Ca2+ store: A pathomechanism shared with amyotrophic lateral sclerosis motor neurons?

Author

Silvia Sapienza, Valentina Tedeschi, Barbara Apicella, Anna Pannaccione, Carmela Russo, Maria Josè Sisalli, Giorgia Magliocca, Stefania Loffredo, and Agnese Secondo

Subjects
Air pollution, Carbon PM, [Ca2+]i homeostasis, ER-stress, Neurotoxicity, SOCE, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350
Abstract

Increased risk of neurodegenerative diseases has been envisaged for air pollution exposure. On the other hand, environmental risk factors, including air pollution, have been suggested for Amyotrophic Lateral Sclerosis (ALS) pathomechanism. Therefore, the neurotoxicity of ultrafine particulate matter (PM0.1) (PM < 0.1 μm size) and its sub-20 nm nanoparticle fraction (NP20) has been investigated in motor neuronal-like cells and primary cortical neurons, mainly affected in ALS. The present data showed that PM0.1 and NP20 exposure induced endoplasmic reticulum (ER) stress, as occurred in cortex and spinal cord of ALS mice carrying G93A mutation in SOD1 gene. Furthermore, NSC-34 motor neuronal-like cells exposed to PM0.1 and NP20 shared the same proteomic profile on some apoptotic factors with motor neurons treated with the L-BMAA, a neurotoxin inducing Amyotrophic Lateral Sclerosis/Parkinson–Dementia Complex (ALS/PDC). Of note ER stress induced by PM0.1 and NP20 in motor neurons was associated to pathological changes in ER morphology and dramatic reduction of organellar Ca2+ level through the dysregulation of the Ca2+-pumps SERCA2 and SERCA3, the Ca2+-sensor STIM1, and the Ca2+-release channels RyR3 and IP3R3. Furthermore, the mechanism deputed to ER Ca2+ refilling (e.g. the so called store operated calcium entry-SOCE) and the relative currents ICRAC were also altered by PM0.1 and NP20 exposure. Additionally, these carbonaceous particles caused the exacerbation of L-BMAA-induced ER stress and Caspase-9 activation. In conclusion, this study shows that PM0.1 and NP20 induced the aberrant expression of ER proteins leading to dysmorphic ER, organellar Ca2+ dysfunction, ER stress and neurotoxicity, providing putative correlations with the neurodegenerative process occurring in ALS.

Published
2024
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207. Data formats and standards for opportunistic rainfall sensors [version 2; peer review: 2 approved]

Author

Martin Fencl, Jafet C. M. Andersson, Roberto Nebuloni, Nico Blettner, Vojtech Bares, Christian Chwala, Greta Cazzaniga, Lotte de Vos, Matteo Colli, Charles Galdies, Abbas El Hachem, Maximilian Graf, Filippo Giannetti, Hai Victor Habi, Dror Jacoby, Jonatan Ostrometzky, Petr Musil, Fabiola Sapienza, Giacomo Roversi, Anna Spackova, Jochen Seidel, Bas Walraven, Remco van de Beek, Xin Zheng, and Karina Wilgan

Subjects
opportunistic rainfall sensing, data standards, data format, naming conventions, commercial microwave links, satelllite microwave links, eng, Science, Social Sciences
Abstract

Opportunistic sensors are increasingly used for rainfall measurement. However, their raw data are collected by a variety of systems that are often not primarily intended for rainfall monitoring, resulting in a plethora of different data formats and a lack of common standards. This hinders the sharing of opportunistic sensing (OS) data, their automated processing, and, at the end, their practical usage and integration into standard observation systems. This paper summarises the experiences of the more than 100 members of the OpenSense Cost Action involved in the OS of rainfall. We review the current practice of collecting and storing precipitation OS data and corresponding metadata, and propose new common guidelines describing the requirements on data and metadata collection, harmonising naming conventions, and defining human-readable and machine readable file formats for data and metadata storage. We focus on three sensors identified by the OpenSense community as prominent representatives of the OS of precipitation: Commercial microwave links (CML): fixed point-to-point radio links mainly used as backhauling connections in telecommunication networks Satellite microwave links (SML): radio links between geostationary Earth orbit (GEO) satellites and ground user terminals. Personal weather stations (PWS): non-professional meteorological sensors owned by citizens. The conventions presented in this paper are primarily designed for storing, handling, and sharing historical time series and do not consider specific requirements for using OS data in real time for operational purposes. The conventions are already now accepted by the ever growing OpenSense community and represent an important step towards automated processing of OS raw data and community development of joint OS software packages.

Published
2024
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208. Proximal humeral multiple fragment fractures in patients over 55: Comparison between Conservative treatment and Plate Fixation

Author

Marco Sapienza, Vito Pavone, Liliana Muscarà, Pierpaolo Panebianco, Alessia Caldaci, Kathryn Louise McCracken, Giuseppe Condorelli, Vincenzo Fabrizio Caruso, Danilo Costa, Angelo Di Giunta, and Gianluca Testa

Subjects
Humerus proximal fracture, Trauma, Surgical technique, Conservative treatment, Comparison, Science (General), Q1-390, Social sciences (General), H1-99
Abstract

Proximal humerus fractures account for about 5% of fragility fractures. These involve a significant burden of disability and a reduced quality of life. This study aims to compare functional results and surgical outcomes (closed reduction and internal fixation with the internal closure system of the proximal humerus) and the conservative management of proximal humerus fractures by 2-, 3-, 4-parts, in patients older than 55 years. Between January 2017 and April 2019, 65 patients with 2, 3 or 4-part fractures were retrospectively analyzed: 29 patients (5 males and 24 females) with an average age of 70.8 ± 9.9 years treated non-surgically (conservative group (CG)) and 36 patients (11 males and 25 females) with an average age of 66.2 ± 7.1 years treated surgically with plate fixation (operating group (OG)). Using different evaluation scores, we compared the OG and the CG. Through the DASH score we have seen how at 12 months there is a satisfactory result in patients with conservative treatment (p = 0.0019). Constant-Murley scale shows no difference between the two treatments (p = 0.2300). BARTHEL scale and SST score did not give statistically satisfactory results. Also, after one year of follow-up, patients treated with conservative therapy had a higher improvement in their Range of Motion (ROM) values than patients treated with surgical treatment. The results in terms of pain in NPRS at 3, 6, 12 months are better for conservative groups (p = 0,0000). Our findings suggest that conservative treatment in proximal humeral fractures, particularly in multi-fragmented fractures in patients over 55 years of age, designs an excellent alternative to the surgical option.

Published
2024
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209. Functional Capacity Impairment in Symptomatic Severe Aortic Stenosis: inline Quantitative Stress Myocardial Perfusion Imaging Predicts Six Minute Walk Test

Author

Jonathan Bennett, MD, MSc, George Thornton, MD, Nikoo Aziminia, MD, BSc, Christian Nitsche, MD, PhD, Francisco Gama, MD, William Procter, MSc, Tiago Fernandes, BSc, Jeanelle Generoso, MSc, Maria Sapienza, MSc, Rachael Harrison, MSc, Iain Pierce, PhD, Charlotte H. Manisty, MD, PhD, Alun Hughes, MD, PhD, Rhodri Davies, MD, PhD, James Moon, MD, Peter Kellman, PhD, and Thomas Treibel, MD, PhD

Subjects
Diseases of the circulatory (Cardiovascular) system, RC666-701
Published
2024
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210. Probing Shocked Ejecta in SN 1987A: A Novel Diagnostic Approach Using XRISM-Resolve

Author

Vincenzo Sapienza, Marco Miceli, Aya Bamba, Salvatore Orlando, Shiu-Hang Lee, Shigehiro Nagataki, Masaomi Ono, Satoru Katsuda, Koji Mori, Makoto Sawada, Yukikatsu Terada, Roberta Giuffrida, and Fabrizio Bocchino

Subjects
Interstellar medium, Supernova remnants, High energy astrophysics, Plasma astrophysics, Astrophysics, QB460-466
Abstract

Supernova (SN) 1987A is one of the best candidates to exploit the capabilities of the freshly launched XRISM satellite. This celestial object offers the unique opportunity to study the evolution of an SN into a young supernova remnant. To date, the X-ray emission has been dominated by the shocked circumstellar medium, with no shocked ejecta firmly detected. However, recent studies provide compelling evidence that in the forthcoming years, the X-ray emission from SN 1987A will increasingly stem from the ejecta. Our aim is to assess the proficiency of the XRISM-Resolve high-resolution spectrometer in pinpointing signatures of the shocked ejecta in SN 1987A. Taking advantage of a self-consistent state-of-the-art magneto-hydrodynamic simulation that describes the evolution from SN 1987A to its remnant, we synthesized the XRISM-Resolve spectrum of SN 1987A, as it would be collected in the allocated observation during the performance verification phase, which is foreseen for 2024. Our predictions clearly show the leading role of shocked ejecta in shaping the profile of the emission lines. The Doppler broadening associated with the bulk motion along the line of sight of the rapidly expanding ejecta is shown to increase the line widths well above the values observed so far. The quantitative comparison between our synthetic spectra and the XRISM spectra will enable us to establish a strong connection between the broadened line emission and the freshly shocked ejecta. This, in turn, will allow us to retrieve the ejecta dynamics and chemical composition from the X-ray emission.

Published
2024
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211. An Update on Patent Ductus Arteriosus and What is Coming Next

Author

Erdeve, Omer, Division of Neonatology, Department of Pediatrics, Okulu, Emel, Singh, Yogen, Sindelar, Richard, Oncel, Mehmet Yekta, Terrin, Gianluca, Boscarino, Giovanni, Bulbul, Ali, Sallmon, Hannes, Atasay, Begum, Ovali, Fahri, Clyman, Ronald I, Division of Neonatology, Loma Linda University School of Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Department of Women’s and Children’s Health, Uppsala University, Division of Neonatology, Buca Seyfi Demirsoy Training and Research Hospital, Department of Maternal and Child Health, University of Roma La Sapienza, Division of Neonatology, Department of Pediatrics University of Health Science, Department of Congenital Heart Disease/Pediatric Cardiology, Charité–Universitätsmedizin Berlin and Deutsches Herzzentrum Berlin, and Department of Pediatrics and Cardiovascular Research Institute, University of California San Francisco

Subjects
Paediatrics, Biomedical and Clinical Sciences, Infant Mortality, Cardiovascular, Pediatric, Preterm, Low Birth Weight and Health of the Newborn, Perinatal Period - Conditions Originating in Perinatal Period, patent ductus arteriosus, preterm, conservative, medical, surgical, treatment
Abstract

Patent ductus arteriosus is the most common cardiovascular condition in preterm infants. There is a significant uncertainty about when and how to close ductus arteriosus in preterm infants due to a high spontaneous closure rate even in very immature preterm infants. Diagnosis and management of patent ductus arteriosus remain a challenge for both neonatologists and pediatric cardiologists. Researchers have tried to define a balance between an expectant approach and active treatment in selected infants. This review aimed to focus on the pathophysiology and management of patent ductus arteriosus and to make suggestions about approaches that might eliminate the association of morbidities with patent ductus arteriosus.

Published
2022

212. Light in correlated disordered media

Author

Vynck, Kevin, Pierrat, Romain, Carminati, Rémi, Froufe-Pérez, Luis S., Scheffold, Frank, Sapienza, Riccardo, Vignolini, Silvia, and Sáenz, Juan José

Subjects
Physics - Optics, Condensed Matter - Disordered Systems and Neural Networks, Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Soft Condensed Matter
Abstract

The optics of correlated disordered media is a fascinating research topic emerging at the interface between the physics of waves in complex media and nanophotonics. Inspired by photonic structures in nature and enabled by advances in nanofabrication processes, recent investigations have unveiled how the design of structural correlations down to the subwavelength scale could be exploited to control the scattering, transport and localization of light in matter. From optical transparency to superdiffusive light transport to photonic gaps, the optics of correlated disordered media challenges our physical intuition and offers new perspectives for applications. This article reviews the theoretical foundations, state-of-the-art experimental techniques and major achievements in the study of light interaction with correlated disorder, covering a wide range of systems -- from short-range correlated photonic liquids, to L\'evy glasses containing fractal heterogeneities, to hyperuniform disordered photonic materials. The mechanisms underlying light scattering and transport phenomena are elucidated on the basis of rigorous theoretical arguments. We overview the exciting ongoing research on mesoscopic phenomena, such as transport phase transitions and speckle statistics, and the current development of disorder engineering for applications such as light-energy management and visual appearance design. Special efforts are finally made to identify the main theoretical and experimental challenges to address in the near future., Comment: Accepted in Reviews of Modern Physics

Published
2021
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213. All You Can Embed: Natural Language based Vehicle Retrieval with Spatio-Temporal Transformers

Author

Scribano, Carmelo, Sapienza, Davide, Franchini, Giorgia, Verucchi, Micaela, and Bertogna, Marko

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

Combining Natural Language with Vision represents a unique and interesting challenge in the domain of Artificial Intelligence. The AI City Challenge Track 5 for Natural Language-Based Vehicle Retrieval focuses on the problem of combining visual and textual information, applied to a smart-city use case. In this paper, we present All You Can Embed (AYCE), a modular solution to correlate single-vehicle tracking sequences with natural language. The main building blocks of the proposed architecture are (i) BERT to provide an embedding of the textual descriptions, (ii) a convolutional backbone along with a Transformer model to embed the visual information. For the training of the retrieval model, a variation of the Triplet Margin Loss is proposed to learn a distance measure between the visual and language embeddings. The code is publicly available at https://github.com/cscribano/AYCE_2021., Comment: CVPR 2021 AI CITY CHALLENGE Natural Language-Based Vehicle Retrieval

Published
2021

214. Coded masks for imaging of neutrino events

Author

Andreotti, M., Bernardini, P., Bersani, A., Bertolucci, S., Biagi, S., Branca, A., Brizzolari, C., Brunetti, G., Cagnoli, I., Calabrese, R., Caminata, A., Campani, A., Carniti, P., Cataldo, R., Cattadori, C., Cherubini, S., Cicero, V., Citterio, M., Copello, S., Cova, P., Morales, E. Cristaldo, Davini, S., Delmonte, N., De Matteis, G., Di Domizio, S., Di Noto, L., Distefano, C., Giammaria, T., Guarise, M., Falcone, A., Ferraro, F., Fiorini, M., Gallice, N., Gotti, C., Guerzoni, M., Iliescu, M. A., Ingratta, G., Lazzaroni, M., Lax, I., Laurenti, G., Leaci, A., Luppi, E., Martina, L., Mauri, N., Minotti, A., Moggi, N., Montagna, E., Montanari, A., Montanino, D., Pallavicini, M., Panareo, M., Parozzi, E. G., Pasqualini, L., Patrizii, L., Pessina, G., Poppi, F., Pozzato, M., Pia, V., Riboldi, S., Riccobene, G., Sala, P., Sapienza, P., Schifano, F., Sirri, G., Spanu, M., Stanco, L., Surdo, A., Taibi, A., Tenti, M., Terranova, F., Testera, G., Tomassetti, L., Torti, M., Tosi, N., Travaglini, R., Uboldi, L., Vicenzi, M., Zani, A., and Zucchelli, S.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

The capture of scintillation light emitted by liquid Argon and Xenon under molecular excitations by charged particles is still a challenging task. Here we present a first attempt to design a device able to grab sufficiently high luminosity in order to reconstruct the path of ionizing particles. This preliminary study is based on the use of masks to encode the light signal combined with single-photon detectors. In this respect, the proposed system is able to detect tracks over focal distances of about tens of centimeters. From numerical simulations it emerges that it is possible to successfully decode and recognize signals, even complex, with a relatively limited number of acquisition channels. Such innovative technique can be very fruitful in a new generation of detectors devoted to neutrino physics and dark matter search. Indeed the introduction of coded masks combined with SiPM detectors is proposed for a liquid-Argon target in the Near Detector of the DUNE experiment.

Published
2021
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220. Hybrid AI Analysis of the Drug Micro-trafficking in Italy

Author

Sapienza, Salvatore, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Kö, Andrea, editor, Francesconi, Enrico, editor, Asemi, Adeleh, editor, Kotsis, Gabriele, editor, Tjoa, A Min, editor, and Khalil, Ismail, editor

Published
2023
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225. Primary care pediatricians and job satisfaction: a cross sectional study in the Lazio region

Author

Martina Sapienza, Giuseppe Furia, Domenico Paolo La Regina, Valentina Grimaldi, Maria Grazia Tarsitano, Cristina Patrizi, Giovanni Capelli, Rome OMCeO Group, and Gianfranco Damiani

Subjects
Primary Care Pediatricians, Job satisfaction, Pediatric Primary Care Units, Omceo Rome, Pediatricians work life balance, Pediatrics, RJ1-570
Abstract

Abstract Background The Order of Physicians and Dentists of the Province of Rome aims at focusing on the satisfaction of healthcare personnel as an essential factor for the quality of medical care in the health sector. The aim of this study is to assess and prioritize the factors that can be linked to a higher or lower degree of job satisfaction in Primary Care Pediatricians (PCPs). Methods This study is a cross sectional survey. A questionnaire was administered to all primary care pediatricians registered to the Order, exploring in particular the work activity organization, the level of satisfaction in their professional life, and the level of perceived health. A pilot activity was conducted to validate the questionnaire. Fisher exact test and ordinal logistic regression (ologit) models were used for the univariate and multivariate analysis. Results The highest level of job dissatisfaction, in both men and women, was found to be in the practice type without any form of association; among women, it reached an even higher level for those who had their own practice at a distance of 20–40 km from their home. Women, compared to men, maintained a lower level of job satisfaction also while working in Pediatric Primary Care Units (PPCUs). In PPCUs, for the same distance, females showed a more similar pattern to males. Men working in PPCUs, regardless of distance, declared a higher degree of job satisfaction. Both men and women, working as a group pediatrician or in PPCUs, did not show a significant difference in the level of job satisfaction. Conclusions The study contributes to a deeper understanding of the factors that may influence levels of career satisfaction in female and male PCPs. Therefore, research and interventions regarding job satisfaction should foster an organizational network connection among PCPs for their job and individual well-being, from a perspective of enhancing patient care. A major effort to improve work-life balance and career satisfaction among women is important, suggesting that interventions for improving job satisfaction could benefit from a gender-specific approach.

Published
2023
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226. Reconstruction of interactions in the ProtoDUNE-SP detector with Pandora

Author

A. Abed Abud, B. Abi, R. Acciarri, M. A. Acero, M. R. Adames, G. Adamov, M. Adamowski, D. Adams, M. Adinolfi, C. Adriano, A. Aduszkiewicz, J. Aguilar, Z. Ahmad, J. Ahmed, B. Aimard, F. Akbar, B. Ali-Mohammadzadeh, K. Allison, S. Alonso Monsalve, M. AlRashed, C. Alt, A. Alton, R. Alvarez, P. Amedo, J. Anderson, C. Andreopoulos, M. Andreotti, M. Andrews, F. Andrianala, S. Andringa, N. Anfimov, A. Ankowski, M. Antoniassi, M. Antonova, A. Antoshkin, S. Antusch, A. Aranda-Fernandez, L. Arellano, L. O. Arnold, M. A. Arroyave, J. Asaadi, L. Asquith, A. Aurisano, V. Aushev, D. Autiero, V. Ayala Lara, M. Ayala-Torres, F. Azfar, A. Back, H. Back, J. J. Back, C. Backhouse, I. Bagaturia, L. Bagby, N. Balashov, S. Balasubramanian, P. Baldi, B. Baller, B. Bambah, F. Barao, G. Barenboim, G. Barker, W. Barkhouse, C. Barnes, G. Barr, J. Barranco Monarca, A. Barros, N. Barros, J. L. Barrow, A. Basharina-Freshville, A. Bashyal, V. Basque, C. Batchelor, J. Battat, F. Battisti, F. Bay, M. C. Q. Bazetto, J. L. Bazo Alba, J. F. Beacom, E. Bechetoille, B. Behera, E. Belchior Batista das Chagas, L. Bellantoni, G. Bellettini, V. Bellini, O. Beltramello, N. Benekos, C. Benitez Montiel, F. Bento Neves, J. Berger, S. Berkman, P. Bernardini, R. M. Berner, A. Bersani, S. Bertolucci, M. Betancourt, A. Betancur Rodríguez, A. Bevan, Y. Bezawada, A. T. Bezerra, T. J. Bezerra, A. Bhardwaj, V. Bhatnagar, M. Bhattacharjee, D. Bhattarai, S. Bhuller, B. Bhuyan, S. Biagi, J. Bian, M. Biassoni, K. Biery, B. Bilki, M. Bishai, A. Bitadze, A. Blake, F. D. M. Blaszczyk, G. C. Blazey, E. Blucher, J. Boissevain, S. Bolognesi, T. Bolton, L. Bomben, M. Bonesini, C. Bonilla-Diaz, F. Bonini, A. Booth, F. Boran, S. Bordoni, A. Borkum, N. Bostan, P. Bour, D. Boyden, J. Bracinik, D. Braga, D. Brailsford, A. Branca, A. Brandt, J. Bremer, C. Brew, S. J. Brice, C. Brizzolari, C. Bromberg, J. Brooke, A. Bross, G. Brunetti, M. Brunetti, N. Buchanan, H. Budd, I. Butorov, I. Cagnoli, T. Cai, D. Caiulo, R. Calabrese, P. Calafiura, J. Calcutt, M. Calin, S. Calvez, E. Calvo, A. Caminata, A. Campos Benitez, D. Caratelli, D. Carber, J. M. Carceller, G. Carini, B. Carlus, M. F. Carneiro, P. Carniti, I. Caro Terrazas, H. Carranza, T. Carroll, J. F. Castaño Forero, A. Castillo, C. Castromonte, E. Catano-Mur, C. Cattadori, F. Cavalier, G. Cavallaro, F. Cavanna, S. Centro, G. Cerati, A. Cervelli, A. Cervera Villanueva, M. Chalifour, A. Chappell, E. Chardonnet, N. Charitonidis, A. Chatterjee, S. Chattopadhyay, M. S. Chavarry Neyra, H. Chen, M. Chen, Y. Chen, Z. Chen, Z. Chen-Wishart, Y. Cheon, D. Cherdack, C. Chi, S. Childress, R. Chirco, A. Chiriacescu, K. Cho, S. Choate, D. Chokheli, P. S. Chong, A. Christensen, D. Christian, G. Christodoulou, A. Chukanov, M. Chung, E. Church, V. Cicero, P. Clarke, G. Cline, T. E. Coan, A. G. Cocco, J. Coelho, J. Collot, N. Colton, E. Conley, R. Conley, J. Conrad, M. Convery, S. Copello, P. Cova, L. Cremaldi, L. Cremonesi, J. I. Crespo-Anadón, M. Crisler, E. Cristaldo, J. Crnkovic, R. Cross, A. Cudd, C. Cuesta, Y. Cui, D. Cussans, J. Dai, O. Dalager, H. Da Motta, L. Da Silva Peres, C. David, Q. David, G. S. Davies, S. Davini, J. Dawson, K. De, S. De, P. Debbins, I. De Bonis, M. Decowski, A. De Gouvea, P. C. De Holanda, I. L. De Icaza Astiz, A. Deisting, P. De Jong, A. Delbart, V. De Leo, D. Delepine, M. Delgado, A. Dell’Acqua, N. Delmonte, P. De Lurgio, J. R. De Mello Neto, D. M. DeMuth, S. Dennis, C. Densham, G. W. Deptuch, A. De Roeck, V. De Romeri, G. De Souza, R. Devi, R. Dharmapalan, M. Dias, J. Diaz, F. Díaz, F. Di Capua, A. Di Domenico, S. Di Domizio, L. Di Giulio, P. Ding, L. Di Noto, G. Dirkx, C. Distefano, R. Diurba, M. Diwan, Z. Djurcic, D. Doering, S. Dolan, F. Dolek, M. Dolinski, L. Domine, Y. Donon, D. Douglas, A. Dragone, G. Drake, F. Drielsma, L. Duarte, D. Duchesneau, K. Duffy, P. Dunne, B. Dutta, H. Duyang, O. Dvornikov, D. Dwyer, A. Dyshkant, M. Eads, A. Earle, D. Edmunds, J. Eisch, L. Emberger, S. Emery, P. Englezos, A. Ereditato, T. Erjavec, C. Escobar, L. Escudero Sanchez, G. Eurin, J. J. Evans, E. Ewart, A. C. Ezeribe, K. Fahey, A. Falcone, M. Fani’, C. Farnese, Y. Farzan, D. Fedoseev, J. Felix, Y. Feng, E. Fernandez-Martinez, P. Fernandez Menendez, F. Ferraro, L. Fields, P. Filip, F. Filthaut, R. Fine, G. Fiorillo, M. Fiorini, V. Fischer, R. S. Fitzpatrick, W. Flanagan, B. Fleming, R. Flight, S. Fogarty, W. Foreman, J. Fowler, W. Fox, J. Franc, K. Francis, D. Franco, J. Freeman, J. Freestone, J. Fried, A. Friedland, S. Fuess, I. K. Furic, K. Furman, A. P. Furmanski, A. Gabrielli, A. Gago, H. Gallagher, A. Gallas, A. Gallego-Ros, N. Gallice, V. Galymov, E. Gamberini, T. Gamble, F. Ganacim, R. Gandhi, S. Ganguly, F. Gao, S. Gao, D. Garcia-Gamez, M. Á. García-Peris, S. Gardiner, D. Gastler, J. Gauvreau, P. Gauzzi, G. Ge, N. Geffroy, B. Gelli, A. Gendotti, S. Gent, Z. Ghorbani-Moghaddam, P. Giammaria, T. Giammaria, N. Giangiacomi, D. Gibin, I. Gil-Botella, S. Gilligan, C. Girerd, A. Giri, D. Gnani, O. Gogota, M. Gold, S. Gollapinni, K. Gollwitzer, R. A. Gomes, L. Gomez Bermeo, L. S. Gomez Fajardo, F. Gonnella, D. González Caamaño, D. Gonzalez-Diaz, M. Gonzalez-Lopez, M. C. Goodman, O. Goodwin, S. Goswami, C. Gotti, E. Goudzovski, C. Grace, R. Gran, E. Granados, P. Granger, C. Grant, D. Gratieri, P. Green, S. Green, S. Greenberg, L. Greenler, J. Greer, J. Grenard, C. Griffith, M. Groh, J. Grudzinski, K. Grzelak, W. Gu, E. Guardincerri, V. Guarino, M. Guarise, R. Guenette, E. Guerard, M. Guerzoni, D. Guffanti, A. Guglielmi, B. Guo, A. Gupta, V. Gupta, K. Guthikonda, P. Guzowski, M. M. Guzzo, S. Gwon, C. Ha, K. Haaf, A. Habig, H. Hadavand, R. Haenni, A. Hahn, J. Haiston, P. Hamacher-Baumann, T. Hamernik, P. Hamilton, J. Han, D. A. Harris, J. Hartnell, T. Hartnett, J. Harton, T. Hasegawa, C. Hasnip, R. Hatcher, K. W. Hatfield, A. Hatzikoutelis, C. Hayes, K. Hayrapetyan, J. Hays, E. Hazen, M. He, A. Heavey, K. M. Heeger, J. Heise, S. Henry, M. Hernandez Morquecho, K. Herner, J. Hewes, C. Hilgenberg, T. Hill, S. J. Hillier, A. Himmel, E. Hinkle, L. R. Hirsch, J. Ho, J. Hoff, A. Holin, E. Hoppe, G. A. Horton-Smith, M. Hostert, A. Hourlier, B. Howard, R. Howell, I. Hristova, M. S. Hronek, J. Huang, Z. Hulcher, G. Iles, N. Ilic, A. M. Iliescu, R. Illingworth, G. Ingratta, A. Ioannisian, B. Irwin, L. Isenhower, R. Itay, C. M. Jackson, V. Jain, E. James, W. Jang, B. Jargowsky, F. Jediny, D. Jena, Y. Jeong, C. Jesús-Valls, X. Ji, J. Jiang, L. Jiang, S. Jiménez, A. Jipa, F. Joaquim, W. Johnson, N. Johnston, B. Jones, M. Judah, C. Jung, T. Junk, Y. Jwa, M. Kabirnezhad, A. Kaboth, I. Kadenko, I. Kakorin, A. Kalitkina, D. Kalra, F. Kamiya, D. M. Kaplan, G. Karagiorgi, G. Karaman, A. Karcher, M. Karolak, Y. Karyotakis, S. Kasai, S. P. Kasetti, L. Kashur, N. Kazaryan, E. Kearns, P. Keener, K. J. Kelly, E. Kemp, O. Kemularia, W. Ketchum, S. H. Kettell, M. Khabibullin, A. Khotjantsev, A. Khvedelidze, D. Kim, B. King, B. Kirby, M. Kirby, J. Klein, A. Klustova, T. Kobilarcik, K. Koehler, L. W. Koerner, D. H. Koh, S. Kohn, P. P. Koller, L. Kolupaeva, D. Korablev, M. Kordosky, T. Kosc, U. Kose, V. Kostelecky, K. Kothekar, R. Kralik, L. Kreczko, F. Krennrich, I. Kreslo, W. Kropp, T. Kroupova, S. Kubota, Y. Kudenko, V. A. Kudryavtsev, S. Kuhlmann, S. Kulagin, J. Kumar, P. Kumar, P. Kunze, R. Kuravi, N. Kurita, C. Kuruppu, V. Kus, T. Kutter, J. Kvasnicka, D. Kwak, A. Lambert, B. Land, C. E. Lane, K. Lang, T. Langford, M. Langstaff, J. Larkin, P. Lasorak, D. Last, A. Laundrie, G. Laurenti, A. Lawrence, I. Lazanu, R. LaZur, M. Lazzaroni, T. Le, S. Leardini, J. Learned, P. LeBrun, T. LeCompte, C. Lee, S. Lee, G. Lehmann Miotto, R. Lehnert, M. Leigui de Oliveira, M. Leitner, L. M. Lepin, S. Li, Y. Li, H. Liao, C. Lin, Q. Lin, S. Lin, R. A. Lineros, J. Ling, A. Lister, B. R. Littlejohn, J. Liu, Y. Liu, S. Lockwitz, T. Loew, M. Lokajicek, I. Lomidze, K. Long, T. Lord, J. LoSecco, W. C. Louis, X. Lu, K. Luk, B. Lunday, X. Luo, E. Luppi, T. Lux, V. P. Luzio, J. Maalmi, D. MacFarlane, A. Machado, P. Machado, C. Macias, J. Macier, A. Maddalena, A. Madera, P. Madigan, S. Magill, K. Mahn, A. Maio, A. Major, J. A. Maloney, G. Mandrioli, R. C. Mandujano, J. C. Maneira, L. Manenti, S. Manly, A. Mann, K. Manolopoulos, M. Manrique Plata, V. N. Manyam, M. Marchan, A. Marchionni, W. Marciano, D. Marfatia, C. Mariani, J. Maricic, R. Marie, F. Marinho, A. D. Marino, T. Markiewicz, D. Marsden, M. Marshak, C. Marshall, J. Marshall, J. Marteau, J. Martín-Albo, N. Martinez, D. A. Martinez Caicedo, P. Martínez Miravé, S. Martynenko, V. Mascagna, K. Mason, A. Mastbaum, F. Matichard, S. Matsuno, J. Matthews, C. Mauger, N. Mauri, K. Mavrokoridis, I. Mawby, R. Mazza, A. Mazzacane, E. Mazzucato, T. McAskill, E. McCluskey, N. McConkey, K. S. McFarland, C. McGrew, A. McNab, A. Mefodiev, P. Mehta, P. Melas, O. Mena, H. Mendez, P. Mendez, D. P. Méndez, A. Menegolli, G. Meng, M. Messier, W. Metcalf, M. Mewes, H. Meyer, T. Miao, G. Michna, V. Mikola, R. Milincic, G. Miller, W. Miller, J. Mills, O. Mineev, A. Minotti, O. G. Miranda, S. Miryala, C. Mishra, S. Mishra, A. Mislivec, M. Mitchell, D. Mladenov, I. Mocioiu, K. Moffat, N. Moggi, R. Mohanta, T. A. Mohayai, N. Mokhov, J. A. Molina, L. Molina Bueno, E. Montagna, A. Montanari, C. Montanari, D. Montanari, D. Montanino, L. M. Montaño Zetina, S. Moon, M. Mooney, A. F. Moor, D. Moreno, D. Moretti, C. Morris, C. Mossey, M. Mote, E. Motuk, C. A. Moura, J. Mousseau, G. Mouster, W. Mu, L. Mualem, J. Mueller, M. Muether, S. Mufson, F. Muheim, A. Muir, M. Mulhearn, D. Munford, H. Muramatsu, M. Murphy, S. Murphy, J. Musser, J. Nachtman, Y. Nagai, S. Nagu, M. Nalbandyan, R. Nandakumar, D. Naples, S. Narita, A. Nath, A. Navrer-Agasson, N. Nayak, M. Nebot-Guinot, K. Negishi, J. K. Nelson, J. Nesbit, M. Nessi, D. Newbold, M. Newcomer, H. Newton, R. Nichol, F. Nicolas-Arnaldos, A. Nikolica, E. Niner, K. Nishimura, A. Norman, A. Norrick, R. Northrop, P. Novella, J. A. Nowak, M. Oberling, J. Ochoa-Ricoux, A. Olivier, A. Olshevskiy, Y. Onel, Y. Onishchuk, J. Ott, L. Pagani, G. Palacio, O. Palamara, S. Palestini, J. M. Paley, M. Pallavicini, C. Palomares, W. Panduro Vazquez, E. Pantic, V. Paolone, V. Papadimitriou, R. Papaleo, A. Papanestis, S. Paramesvaran, S. Parke, E. Parozzi, Z. Parsa, M. Parvu, S. Pascoli, L. Pasqualini, J. Pasternak, J. Pater, C. Patrick, L. Patrizii, R. B. Patterson, S. Patton, T. Patzak, A. Paudel, B. Paulos, L. Paulucci, Z. Pavlovic, G. Pawloski, D. Payne, V. Pec, S. J. Peeters, A. Pena Perez, E. Pennacchio, A. Penzo, O. L. Peres, J. Perry, D. Pershey, G. Pessina, G. Petrillo, C. Petta, R. Petti, V. Pia, F. Piastra, L. Pickering, F. Pietropaolo, V. L. Pimentel, G. Pinaroli, K. Plows, R. Plunkett, F. Pompa, X. Pons, N. Poonthottathil, F. Poppi, S. Pordes, J. Porter, S. Porzio, M. Potekhin, R. Potenza, B. V. Potukuchi, J. Pozimski, M. Pozzato, S. Prakash, T. Prakash, M. Prest, S. Prince, F. Psihas, D. Pugnere, X. Qian, J. Raaf, V. Radeka, J. Rademacker, B. Radics, A. Rafique, E. Raguzin, M. Rai, M. Rajaoalisoa, I. Rakhno, A. Rakotonandrasana, L. Rakotondravohitra, R. Rameika, M. Ramirez Delgado, B. Ramson, A. Rappoldi, G. Raselli, P. Ratoff, S. Raut, H. Razafinime, R. Razakamiandra, E. M. Rea, J. S. Real, B. Rebel, R. Rechenmacher, M. Reggiani-Guzzo, J. Reichenbacher, S. D. Reitzner, H. Rejeb Sfar, A. Renshaw, S. Rescia, F. Resnati, M. Ribas, S. Riboldi, C. Riccio, G. Riccobene, L. C. Rice, J. S. Ricol, A. Rigamonti, Y. Rigaut, E. V. Rincón, H. Ritchie-Yates, D. Rivera, A. Robert, J. Rocabado Rocha, L. Rochester, M. Roda, P. Rodrigues, J. V. Rodrigues da Silva Leite, M. J. Rodriguez Alonso, J. Rodriguez Rondon, S. Rosauro-Alcaraz, P. Rosier, B. Roskovec, M. Rossella, M. Rossi, J. Rout, P. Roy, A. Rubbia, C. Rubbia, B. Russell, D. Ruterbories, A. Rybnikov, A. Saa-Hernandez, R. Saakyan, S. Sacerdoti, N. Sahu, P. Sala, N. Samios, O. Samoylov, M. Sanchez, V. Sandberg, D. A. Sanders, D. Sankey, N. Saoulidou, P. Sapienza, C. Sarasty, I. Sarcevic, G. Savage, V. Savinov, A. Scaramelli, A. Scarff, A. Scarpelli, T. Schefke, H. Schellman, S. Schifano, P. Schlabach, D. Schmitz, A. W. Schneider, K. Scholberg, A. Schukraft, E. Segreto, A. Selyunin, C. R. Senise, J. Sensenig, D. Sgalaberna, M. Shaevitz, S. Shafaq, F. Shaker, M. Shamma, R. Sharankova, H. R. Sharma, R. Sharma, R. K. Sharma, K. Shaw, T. Shaw, K. Shchablo, C. Shepherd-Themistocleous, A. Sheshukov, S. Shin, I. Shoemaker, D. Shooltz, R. Shrock, H. Siegel, L. Simard, J. Sinclair, G. Sinev, J. Singh, L. Singh, P. Singh, V. Singh, R. Sipos, F. Sippach, G. Sirri, A. Sitraka, K. Siyeon, K. Skarpaas, E. Smith, P. Smith, J. Smolik, M. Smy, E. Snider, P. Snopok, D. Snowden-Ifft, M. Soares Nunes, H. Sobel, M. Soderberg, S. Sokolov, C. J. Solano Salinas, S. Söldner-Rembold, S. Soleti, N. Solomey, V. Solovov, W. E. Sondheim, M. Sorel, A. Sotnikov, J. Soto-Oton, F. Soto Ugaldi, A. Sousa, K. Soustruznik, F. Spagliardi, M. Spanu, J. Spitz, N. J. C. Spooner, K. Spurgeon, M. Stancari, L. Stanco, C. Stanford, R. Stein, H. Steiner, A. F. Steklain Lisbôa, J. Stewart, B. Stillwell, J. Stock, F. Stocker, T. Stokes, M. Strait, T. Strauss, L. Strigari, A. Stuart, J. G. Suarez, J. Suárez Sunción, H. Sullivan, A. Surdo, V. Susic, L. Suter, C. Sutera, Y. Suvorov, R. Svoboda, B. Szczerbinska, A. M. Szelc, N. Talukdar, H. Tanaka, S. Tang, B. Tapia Oregui, A. Tapper, S. Tariq, E. Tarpara, N. Tata, E. Tatar, R. Tayloe, A. Teklu, P. Tennessen, M. Tenti, K. Terao, C. A. Ternes, F. Terranova, G. Testera, T. Thakore, A. Thea, C. Thorn, S. Timm, V. Tishchenko, L. Tomassetti, A. Tonazzo, D. Torbunov, M. Torti, M. Tortola, F. Tortorici, N. Tosi, D. Totani, M. Toups, C. Touramanis, R. Travaglini, J. Trevor, S. Trilov, W. H. Trzaska, Y. Tsai, Z. Tsamalaidze, K. Tsang, N. Tsverava, S. Z. Tu, S. Tufanli, C. Tull, J. Tyler, E. Tyley, M. Tzanov, L. Uboldi, M. A. Uchida, J. Urheim, T. Usher, S. Uzunyan, M. R. Vagins, P. Vahle, S. Valder, G. D. Valdiviesso, E. Valencia, R. Valentim, Z. Vallari, E. Vallazza, J. W. Valle, S. Vallecorsa, R. Van Berg, R. G. Van de Water, D. Vanegas Forero, D. Vannerom, F. Varanini, D. Vargas Oliva, G. Varner, J. Vasel, S. Vasina, G. Vasseur, N. Vaughan, K. Vaziri, S. Ventura, A. Verdugo, S. Vergani, M. A. Vermeulen, M. Verzocchi, M. Vicenzi, H. Vieira de Souza, C. Vignoli, C. Vilela, B. Viren, T. Vrba, T. Wachala, A. V. Waldron, M. Wallbank, C. Wallis, T. Walton, H. Wang, J. Wang, L. Wang, M. H. Wang, X. Wang, Y. Wang, K. Warburton, D. Warner, M. Wascko, D. Waters, A. Watson, K. Wawrowska, P. Weatherly, A. Weber, M. Weber, H. Wei, A. Weinstein, D. Wenman, M. Wetstein, A. White, L. H. Whitehead, D. Whittington, M. J. Wilking, A. Wilkinson, C. Wilkinson, Z. Williams, F. Wilson, R. J. Wilson, W. Wisniewski, J. Wolcott, T. Wongjirad, A. Wood, K. Wood, E. Worcester, M. Worcester, K. Wresilo, C. Wret, W. Wu, Y. Xiao, B. Yaeggy, E. Yandel, G. Yang, K. Yang, T. Yang, A. Yankelevich, N. Yershov, K. Yonehara, Y. Yoon, T. Young, B. Yu, H. Yu, J. Yu, Y. Yu, W. Yuan, R. Zaki, J. Zalesak, L. Zambelli, B. Zamorano, A. Zani, L. Zazueta, G. Zeller, J. Zennamo, K. Zeug, C. Zhang, S. Zhang, Y. Zhang, M. Zhao, E. Zhivun, G. Zhu, E. D. Zimmerman, S. Zucchelli, J. Zuklin, V. Zutshi, R. Zwaska, and DUNE Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The Pandora Software Development Kit and algorithm libraries provide pattern-recognition logic essential to the reconstruction of particle interactions in liquid argon time projection chamber detectors. Pandora is the primary event reconstruction software used at ProtoDUNE-SP, a prototype for the Deep Underground Neutrino Experiment far detector. ProtoDUNE-SP, located at CERN, is exposed to a charged-particle test beam. This paper gives an overview of the Pandora reconstruction algorithms and how they have been tailored for use at ProtoDUNE-SP. In complex events with numerous cosmic-ray and beam background particles, the simulated reconstruction and identification efficiency for triggered test-beam particles is above 80% for the majority of particle type and beam momentum combinations. Specifically, simulated 1 GeV/c charged pions and protons are correctly reconstructed and identified with efficiencies of 86.1 $$\pm 0.6$$ ± 0.6 % and 84.1 $$\pm 0.6$$ ± 0.6 %, respectively. The efficiencies measured for test-beam data are shown to be within 5% of those predicted by the simulation.

Published
2023
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227. Attachment and parental bond: impact on psychopathology, mental health and quality of life of hemodialysis patients: a cross-sectional study

Author

Concetta De Pasquale, Maria Luisa Pistorio, Massimiliano Veroux, Gabriella Sapienza, Alberto Florio, Zira Hichy, Burcin Ekser, Alessia Giaquinta, and Pierfrancesco Veroux

Subjects
Attachment, Parental bond, Psychopathology, Hemodialysis, Quality of life, Mental health, Psychology, BF1-990
Abstract

Abstract Background Attachment theory represents a reference model for understanding better how pre-existing personality factors can influence the coping with some chronic conditions. The onset of a chronic disease can represent a "threat" to the relationships between the subject and parental figures according to the type of bond that already exists. The aim of our study was to explore attachment styles in a sample of hemodialysis patients, hypothesizing that a secure attachment bond can constitute a protective factor for the quality of life and mental health in this type of patients. Design We used a cross-sectional design. Methods Fifty hemodialysis patients were given the following tests: Attachment Style Questionnaire (ASQ) to assess attachment styles, Parental Bonding Instrument (PBI) to assess parental bonding, Short Form Health Survey-36 (SF-36) for perceived quality of life and Middlesex Hospital Questionnaire (MHQ) to detect key psychological symptoms and relevant traits. Results The results showed that secure attachment style correlated with good general health (r = 0.339; p

Published
2023
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233. Embedded software of the KM3NeT central logic board

Author

Aiello, S., Albert, A., Alves Garre, S., Aly, Z., Ambrosone, A., Ameli, F., Andre, M., Androutsou, E., Anghinolfi, M., Anguita, M., Aphecetche, L., Ardid, M., Ardid, S., Atmani, H., Aublin, J., Bagatelas, C., Bailly-Salins, L., Bardačová, Z., Baret, B., Basegmez du Pree, S., Becherini, Y., Bendahman, M., Benfenati, F., Benhassi, M., Benoit, D.M., Berbee, E., Bertin, V., van Beveren, V., Biagi, S., Boettcher, M., Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Bozza, R.M., Brânzaş, H., Bretaudeau, F., Bruijn, R., Brunner, J., Bruno, R., Buis, E., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Campion, S., Capone, A., Carenini, F., Carretero, V., Cartraud, T., Castaldi, P., Cecchini, V., Celli, S., Cerisy, L., Chabab, M., Chadolias, M., Chen, A., Cherubini, S., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J.A.B., Coleiro, A., Coniglione, R., Coyle, P., Creusot, A., Cruz, A., Cuttone, G., Dallier, R., Darras, Y., De Benedittis, A., De Martino, B., Decoene, V., Del Burgo, R., Di Mauro, L.S., Di Palma, I., Díaz, A.F., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dornic, D., Dörr, M., Drakopoulou, E., Drouhin, D., Dvornický, R., Eberl, T., Eckerová, E., Eddymaoui, A., van Eeden, T., Eff, M., van Eijk, D., El Bojaddaini, I., El Hedri, S., Enzenhöfer, A., Ferrara, G., Filipović, M.D., Filippini, F., Fusco, L.A., Gabella, O., Gabriel, J., Gagliardini, S., Gal, T., García Méndez, J., Garcia Soto, A., Gatius Oliver, C., Geißelbrecht, N., Ghaddari, H., Gialanella, L., Gibson, B.K., Giorgio, E., Girardi, A., Goos, I., Goupilliere, D., Gozzini, S.R., Gracia, R., Graf, K., Guidi, C., Guillon, B., Gutiérrez, M., van Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Hernández-Rey, J.J., Huang, F., Idrissi Ibnsalih, W., Illuminati, G., James, C.W., Jansweijer, P., de Jong, M., de Jong, P., Jung, B.J., Kalaczyński, P., Kalekin, O., Katz, U.F., Khan Chowdhury, N.R., Khatun, A., Kistauri, G., Kopper, C., Kouchner, A., Kulikovskiy, V., Kvatadze, R., Labalme, M., Lahmann, R., Larosa, G., Lastoria, C., Lazo, A., Le Stum, S., Lehaut, G., Leonora, E., Lessing, N., Levi, G., Lindsey Clark, M., Longhitano, F., Majumdar, J., Malerba, L., Mamedov, F., Mańczak, J., Manfreda, A., Marconi, M., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martínez-Mora, J.A., Marzaioli, F., Mastrodicasa, M., Mastroianni, S., Miccichè, S., Miele, G., Migliozzi, P., Migneco, E., Minutoli, S., Mitsou, M.L., Mollo, C.M., Morales-Gallegos, L., Morley-Wong, C., Mosbrugger, A., Moussa, A., Mozun Mateo, I., Muller, R., Musone, M.R., Musumeci, M., Nauta, L., Navas, S., Nayerhoda, A., Nicolau, C.A., Nkosi, B., Ó Fearraigh, B., Oliviero, V., Orlando, A., Oukacha, E., Palacios González, J., Papalashvili, G., Pastor Gomez, E.J., Păun, A.M., Păvălaş, G.E., Peña Martínez, S., Perrin-Terrin, M., Perronnel, J., Pestel, V., Pestes, R., Piattelli, P., Poirè, C., Popa, V., Pradier, T., Pulvirenti, S., Quéméner, G., Quiroz, C., Rahaman, U., Randazzo, N., Razzaque, S., Rea, I.C., Real, D., Reck, S., Riccobene, G., Robinson, J., Romanov, A., Saina, A., Salesa Greus, F., Samtleben, D.F.E., Sánchez Losa, A., Sanguineti, M., Santonastaso, C., Santonocito, D., Sapienza, P., Scarpetta, Y., Schnabel, J., Schneider, M.F., Schumann, J., Schutte, H.M., Seneca, J., Setter, B., Sgura, I., Shanidze, R., Shitov, Y., Šimkovic, F., Simonelli, A., Sinopoulou, A., Smirnov, M.V., Spisso, B., Spurio, M., Stavropoulos, D., Štekl, I., Taiuti, M., Tayalati, Y., Tedjditi, H., Thiersen, H., Tosta e Melo, I., Trocme, B., Tsagkli, S., Tsourapis, V., Tzamariudaki, E., Vacheret, A., Valsecchi, V., Van Elewyck, V., Vannoye, G., Vasileiadis, G., Vazquez de Sola, F., Verilhac, C., Veutro, A., Viola, S., Vivolo, D., Warnhofer, H., Wilms, J., de Wolf, E., Yepes-Ramirez, H., Zarpapis, G., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J.D., Zúñiga, J., and Zywucka, N.

Published
2024
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237. The cognitive architecture of verbal humor in schizophrenia

Author

Agostoni, Giulia, Bischetti, Luca, Repaci, Federica, Bechi, Margherita, Spangaro, Marco, Ceccato, Irene, Cavallini, Elena, Fiorentino, Luca, Martini, Francesca, Sapienza, Jacopo, Buonocore, Mariachiara, D'Incalci, Michele Francesco, Cocchi, Federica, Guglielmino, Carmelo, Cavallaro, Roberto, Bosia, Marta, and Bambini, Valentina

Published
2024
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238. Bright single photon emitters with enhanced quantum efficiency in a two-dimensional semiconductor coupled with dielectric nano-antennas

Author

Sortino, Luca, Zotev, Panaiot G., Phillips, Catherine L., Brash, Alistair J., Cambiasso, Javier, Marensi, Elena, Fox, A. Mark, Maier, Stefan A., Sapienza, Riccardo, and Tartakovskii, Alexander I.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

Single photon emitters in atomically-thin semiconductors can be deterministically positioned using strain induced by underlying nano-structures. Here, we couple monolayer WSe$_2$ to high-refractive-index gallium phosphide dielectric nano-antennas providing both optical enhancement and monolayer deformation. For single photon emitters formed on such nano-antennas, we find very low (femto-Joule) saturation pulse energies and up to 10$^4$ times brighter photoluminescence than in WSe$_2$ placed on low-refractive-index SiO$_2$ pillars. We show that the key to these observations is the increase on average by a factor of 5 in the quantum efficiency of the emitters coupled to the nano-antennas. This further allowed us to gain new insights into their photoluminescence dynamics, revealing the roles of the dark exciton reservoir and Auger processes. We also find that the coherence time of such emitters is limited by intrinsic dephasing processes. Our work establishes dielectric nano-antennas as a platform for high-efficiency quantum light generation in monolayer semiconductors.

Published
2021
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239. Search for neutrinos from the tidal disruption events AT2019dsg and AT2019fdr with the ANTARES telescope

Author

ANTARES Collaboration, Albert, A., Alves, S., André, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -J., Aublin, J., Baret, B., Basa, S., Belhorma, B., Bendahman, M., Benfenati, F., Bertin, V., Biagi, S., Bissinger, M., Boumaaza, J., Bouta, M., Bouwhuis, M. C., Brânzaş, H., Bruijn, R., Brunner, J., Busto, J., Caiffi, B., Capone, A., Caramete, L., Carr, J., Carretero, V., Celli, S., Chabab, M., Chau, T. N., Moursli, R. Cherkaoui El, Chiarusi, T., Circella, M., Coleiro, A., Colomer-Molla, M., Coniglione, R., Coyle, P., Creusot, A., Díaz, A. F., de Wasseige, G., Deschamps, A., Distefano, C., Di Palma, I., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., van Eeden, T., Khayati, N. El, Enzenhöfer, A., Fermani, P., Ferrara, G., Filippini, F., Fusco, L., García, R., Gatelet, Y., Gay, P., Glotin, H., Gozzini, R., Graf, K., Guidi, C., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernández-Rey, J. J., Hößl, J., Hofestädt, J., Huang, F., Illuminati, G., James, C. W., Jisse-Jung, B., de Jong, M., de Jong, P., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Khan-Chowdhury, N. R., Kouchner, A., Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Breton, R. Le, Lefèvre, D., Leonora, E., Levi, G., Lincetto, M., Lopez-Coto, D., Loucatos, S., Maderer, L., Manczak, J., Marcelin, M., Margiotta, A., Marinelli, A., Martínez-Mora, J. A., Melis, K., Migliozzi, P., Moser, M., Moussa, A., Muller, R., Nauta, L., Navas, S., Nezri, E., Fearraigh, B. Ó, Organokov, M., Păvălaş, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pieterse, C., Poirè, C., Popa, V., Pradier, T., Randazzo, N., Reck, S., Riccobene, G., Romanov, A., Greus, F. Salesa, Samtleben, D. F. E., Sánchez-Losa, A., Sanguineti, M., Sapienza, P., Schnabel, J., Schumann, J., Schüssler, F., Spurio, M., Stolarczyk, Th., Taiuti, M., Tayalati, Y., Tingay, S. J., Vallage, B., Van Elewyck, V., Versari, F., Viola, S., Vivolo, D., Wilms, J., Zavatarelli, S., Zegarelli, A., Zornoza, J. D., and Zúñiga, J.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

On October 1, 2019, the IceCube Collaboration detected a muon track neutrino with high probability of being of astrophysical origin, IC191001A. After a few hours, the tidal disruption event (TDE) AT2019dsg, observed by the Zwicky Transient Facility (ZTF), was indicated as the most likely counterpart of the IceCube track. More recently, the follow-up campaign of the IceCube alerts by ZTF suggested a second TDE, AT2019fdr, as a promising counterpart of another IceCube muon track candidate, IC200530A, detected on May 30, 2020. These are the second and third associations between astrophysical sources and high-energy neutrinos after the compelling identification of the blazar TXS 0506+056. Here, the search for ANTARES neutrinos from the directions of AT2019dsg and AT2019fdr using a time-integrated approach is presented. As no significant evidence for space clustering is found in the ANTARES data, upper limits on the one-flavour neutrino flux and fluence are set., Comment: 10 pages, 1 figure

Published
2021
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240. Deep Underground Neutrino Experiment (DUNE) Near Detector Conceptual Design Report

Author

Abud, A. Abed, Abi, B., Acciarri, R., Acero, M. A., Adamov, G., Adams, D., Adinolfi, M., Aduszkiewicz, A., Ahmad, Z., Ahmed, J., Alion, T., Monsalve, S. Alonso, Alrashed, M., Alt, C., Alton, A., Amedo, P., Anderson, J., Andreopoulos, C., Andrews, M. P., Andrianala, F., Andringa, S., Anfimov, N., Ankowski, A., Antonova, M., Antusch, S., Aranda-Fernandez, A., Ariga, A., Arnold, L. O., Arroyave, M. A., Asaadi, J., Aurisano, A., Aushev, V., Autiero, D., Ayala-Torres, M., Azfar, F., Back, H., Back, J. J., Backhouse, C., Baesso, P., Bagaturia, I., Bagby, L., Balasubramanian, S., Baldi, P., Baller, B., Bambah, B., Barao, F., Barenboim, G., Barker, G. J., Barkhouse, W., Barnes, C., Barr, G., Monarca, J. Barranco, Barros, N., Barrow, J. L., Basharina-Freshville, A., Bashyal, A., Basque, V., Belchior, E., Battat, J. B. R., Battisti, F., Bay, F., Alba, J. L. Bazo, Beacom, J. F., Bechetoille, E., Behera, B., Bellantoni, L., Bellettini, G., Bellini, V., Beltramello, O., Belver, D., Benekos, N., Neves, F. Bento, Berkman, S., Bernardini, P., Berner, R. M., Berns, H., Bertolucci, S., Betancourt, M., Rodríguez, A. Betancur, Bhattacharjee, M., Bhuller, S., Bhuyan, B., Biagi, S., Bian, J., Biassoni, M., Biery, K., Bilki, B., Bishai, M., Bitadze, A., Blake, A., Blaszczyk, F. D. M., Blazey, G. C., Blucher, E., Boissevain, J., Bolognesi, S., Bolton, T., Bomben, L., Bonesini, M., Bongrand, M., Bonini, F., Booth, A., Booth, C., Bordoni, S., Borkum, A., Boschi, T., Bostan, N., Bour, P., Bourgeois, C., Boyd, S. B., Boyden, D., Bracinik, J., Braga, D., Brailsford, D., Brandt, A., Bremer, J., Brew, C., Brianne, E., Brice, S. J., Brizzolari, C., Bromberg, C., Brooijmans, G., Brooke, J., Bross, A., Brunetti, G., Brunetti, M., Buchanan, N., Budd, H., Caiulo, D., Calafiura, P., Calcutt, J., Calin, M., Calvez, S., Calvo, E., Caminata, A., Campanelli, M., Cankocak, K., Caratelli, D., Carini, G., Carlus, B., Carniti, P., Terrazas, I. Caro, Carranza, H., Carroll, T., Forero, J. F. Castaño, Castillo, A., Castromonte, C., Catano-Mur, E., Cattadori, C., Cavalier, F., Cavanna, F., Centro, S., Cerati, G., Cervelli, A., Villanueva, A. Cervera, Chalifour, M., Chappell, A., Chardonnet, E., Charitonidis, N., Chatterjee, A., Chattopadhyay, S., Chen, H., Chen, M., Chen, Y., Chen, Z., Cherdack, D., Chi, C., Childress, S., Chiriacescu, A., Chisnall, G., Cho, K., Choate, S., Chokheli, D., Choubey, S., Christensen, A., Christian, D., Christodoulou, G., Chukanov, A., Church, E., Clarke, P., Coan, T. E., Cocco, A. G., Coelho, J. A. B., Conley, E., Conley, R., Conrad, J. M., Convery, M., Copello, S., Corwin, L., Cremaldi, L., Cremonesi, L., Crespo-Anadón, J. I., Cristaldo, E., Cross, R., Cudd, A., Cuesta, C., Cui, Y., Cussans, D., Dabrowski, M., Dalager, O., da Motta, H., Peres, L. Da Silva, David, C., David, Q., Davies, G. S., Davini, S., Dawson, J., De, K., De Almeida, R. M., Debbins, P., De Bonis, I., Decowski, M. P., de Gouvêa, A., De Holanda, P. C., Astiz, I. L. De Icaza, Deisting, A., De Jong, P., Delbart, A., Delepine, D., Delgado, M., Dell'Acqua, A., De Lurgio, P., Neto, J. R. T. de Mello, DeMuth, D. M., Dennis, S., Densham, C., Deptuch, G. W., De Roeck, A., De Romeri, V., De Souza, G., Dharmapalan, R., Diaz, F., Díaz, J. S., Di Domizio, S., Di Giulio, L., Ding, P., Di Noto, L., Distefano, C., Diurba, R., Diwan, M., Djurcic, Z., Dokania, N., Dolan, S., Dolinski, M. J., Domine, L., Douglas, D., Douillet, D., Drake, G., Drielsma, F., Duchesneau, D., Duffy, K., Dunne, P., Durkin, T., Duyang, H., Dvornikov, O., Dwyer, D. A., Dyshkant, A. S., Eads, M., Earle, A., Edmunds, D., Eisch, J., Emberger, L., Emery, S., Ereditato, A., Escobar, C. O., Eurin, G., Evans, J. J., Ewart, E., Ezeribe, A. C., Fahey, K., Falcone, A., Farnese, C., Farzan, Y., Felix, J., da Silva, M. Fernandes Carneiro, Fernandez-Martinez, E., Menendez, P. Fernandez, Ferraro, F., Fields, L., Filthaut, F., Fiorentini, A., Fitzpatrick, R. S., Flanagan, W., Fleming, B., Flight, R., Forero, D. V., Fowler, J., Fox, W., Franc, J., Francis, K., Franco, D., Freeman, J., Freestone, J., Fried, J., Friedland, A., Fuess, S., Furic, I., Furmanski, A. P., Gago, A., Gallagher, H., Gallas, A., Gallego-Ros, A., Gallice, N., Galymov, V., Gamberini, E., Gamble, T., Gandhi, R., Gandrajula, R., Gao, F., Gao, S., Garcia-Gamez, D., García-Peris, M. Á, Gardiner, S., Gastler, D., Ge, G., Gelli, B., Gendotti, A., Gent, S., Ghorbani-Moghaddam, Z., Gibin, D., Gil-Botella, I., Gilligan, S., Girerd, C., Giri, A. K., Gnani, D., Gogota, O., Gold, M., Gollapinni, S., Gollwitzer, K., Gomes, R. A., Bermeo, L. V. Gomez, Fajardo, L. S. Gomez, Gonnella, F., Gonzalez-Cuevas, J. A., Gonzalez-Diaz, D., Gonzalez-Lopez, M., Goodman, M. C., Goodwin, O., Goswami, S., Gotti, C., Goudzovski, E., Grace, C., Graham, M., Gran, R., Granados, E., Granger, P., Grant, A., Grant, C., Gratieri, D., Green, P., Greenler, L., Greer, J., Griffith, W. C., Groh, M., Grudzinski, J., Grzelak, K., Gu, W., Guarino, V., Guenette, R., Guerard, E., Guglielmi, A., Guo, B., Guthikonda, K. K., Gutierrez, R., Guzowski, P., Guzzo, M. M., Gwon, S., Habig, A., Hadavand, H., Haenni, R., Hahn, A., Haiston, J., Hamacher-Baumann, P., Hamernik, T., Hamilton, P., Han, J., Harris, D. A., Hartnell, J., Harton, J., Hasegawa, T., Hasnip, C., Hatcher, R., Hatfield, K. W., Hatzikoutelis, A., Hayes, C., Hazen, E., Heavey, A., Heeger, K. M., Heise, J., Hennessy, K., Henry, S., Morquecho, M. A. Hernandez, Herner, K., Hertel, L., Hewes, V, Higuera, A., Hill, T., Hillier, S. J., Himmel, A., Hoff, J., Hohl, C., Holin, A., Hoppe, E., Horton-Smith, G. A., Hostert, M., Hourlier, A., Howard, B., Howell, R., Huang, J., Hugon, J., Iles, G., Ilic, N., Iliescu, A. M., Illingworth, R., Ioannisian, A., Isenhower, L., Itay, R., Izmaylov, A., Jackson, S., Jain, V., James, E., Jargowsky, B., Jediny, F., Jena, D., Jeong, Y. S., Jesús-Valls, C., Ji, X., Jiang, L., Jiménez, S., Jipa, A., Johnson, R., Jones, B., Jones, S. B., Judah, M., Jung, C. K., Junk, T., Jwa, Y., Kabirnezhad, M., Kaboth, A., Kadenko, I., Kakorin, I., Kamiya, F., Kaneshige, N., Karagiorgi, G., Karaman, G., Karcher, A., Karolak, M., Karyotakis, Y., Kasai, S., Kasetti, S. P., Kashur, L., Kazaryan, N., Kearns, E., Keener, P., Kelly, K. J., Kemp, E., Kemularia, O., Ketchum, W., Kettell, S. H., Khabibullin, M., Khotjantsev, A., Khvedelidze, A., Kim, D., King, B., Kirby, B., Kirby, M., Klein, J., Koehler, K., Koerner, L. W., Kohn, S., Koller, P. P., Kolupaeva, L., Kordosky, M., Kosc, T., Kose, U., Kostelecký, V. A., Kothekar, K., Krennrich, F., Kreslo, I., Kudenko, Y., Kudryavtsev, V. A., Kulagin, S., Kumar, J., Kumar, P., Kunze, P., Kurita, N., Kuruppu, C., Kus, V., Kutter, T., Lambert, A., Land, B., Lande, K., Lane, C. E., Lang, K., Langford, T., Larkin, J., Lasorak, P., Last, D., Lastoria, C., Laundrie, A., Lawrence, A., Lazanu, I., LaZur, R., Le, T., Leardini, S., Learned, J., LeBrun, P., LeCompte, T., Miotto, G. Lehmann, Lehnert, R., de Oliveira, M. A. Leigui, Leitner, M., Li, L., Li, S. W., Li, T., Li, Y., Liao, H., Lin, C. S., Lin, Q., Lin, S., Lister, A., Littlejohn, B. R., Liu, J., Lockwitz, S., Loew, T., Lokajicek, M., Lomidze, I., Long, K., Loo, K., Lorca, D., Lord, T., LoSecco, J. M., Louis, W. C., Lu, X. -G., Luk, K. B., Luo, X., Lurkin, N., Lux, T., Luzio, V. P., MacFarlane, D., Machado, A. A., Machado, P., Macias, C. T., Macier, J. R., Maddalena, A., Madera, A., Madigan, P., Magill, S., Mahn, K., Maio, A., Major, A., Maloney, J. A., Mandrioli, G., Mandujano, R. C., Maneira, J., Manenti, L., Manly, S., Mann, A., Manolopoulos, K., Plata, M. Manrique, Manyam, V. N., Manzanillas, L., Marchan, M., Marchionni, A., Marciano, W., Marfatia, D., Mariani, C., Maricic, J., Marie, R., Marinho, F., Marino, A. D., Marsden, D., Marshak, M., Marshall, C. M., Marshall, J., Marteau, J., Martin-Albo, J., Martinez, N., Caicedo, D. A. Martinez, Martynenko, S., Mason, K., Mastbaum, A., Masud, M., Matsuno, S., Matthews, J., Mauger, C., Mauri, N., Mavrokoridis, K., Mawby, I., Mazza, R., Mazzacane, A., Mazzucato, E., McAskill, T., McCluskey, E., McConkey, N., McFarland, K. S., McGrew, C., McNab, A., Mefodiev, A., Mehta, P., Melas, P., Mena, O., Menary, S., Mendez, H., Méndez, D. P., Menegolli, A., Meng, G., Messier, M. D., Metcalf, W., Mettler, T., Mewes, M., Meyer, H., Miao, T., Michna, G., Miedema, T., Migenda, J., Mikola, V., Milincic, R., Miller, W., Mills, J., Milne, C., Mineev, O., Miranda, O. G., Miryala, S., Mishra, C. S., Mishra, S. R., Mislivec, A., Mladenov, D., Mocioiu, I., Moffat, K., Moggi, N., Mohanta, R., Mohayai, T. A., Mokhov, N., Molina, J., Bueno, L. Molina, Montanari, A., Montanari, C., Montanari, D., Zetina, L. M. Montano, Moon, J., Mooney, M., Moor, A. F., Moreno, D., Morris, C., Mossey, C., Motuk, E., Moura, C. A., Mousseau, J., Mu, W., Mualem, L., Mueller, J., Muether, M., Mufson, S., Muheim, F., Muir, A., Mulhearn, M., Munford, D., Muramatsu, H., Murphy, S., Musser, J., Nachtman, J., Nagu, S., Nalbandyan, M., Nandakumar, R., Naples, D., Narita, S., Navas-Nicolás, D., Navrer-Agasson, A., Nayak, N., Nebot-Guinot, M., Negishi, K., Nelson, J. K., Nesbit, J., Nessi, M., Newbold, D., Newcomer, M., Newhart, D., Newton, H., Nichol, R., Nicolas-Arnaldos, F., Niner, E., Nishimura, K., Norman, A., Norrick, A., Northrop, R., Novella, P., Nowak, J. A., Oberling, M., Ochoa-Ricoux, J. P., Del Campo, A. Olivares, Olivier, A., Olshevskiy, A., Onel, Y., Onishchuk, Y., Ott, J., Pagani, L., Pakvasa, S., Palacio, G., Palamara, O., Palestini, S., Paley, J. M., Pallavicini, M., Palomares, C., Palomino-Gallo, J. L., Pantic, E., Paolone, V., Papadimitriou, V., Papaleo, R., Papanestis, A., Paramesvaran, S., Parke, S., Parsa, Z., Parvu, M., Pascoli, S., Pasqualini, L., Pasternak, J., Pater, J., Patrick, C., Patrizii, L., Patterson, R. B., Patton, S. J., Patzak, T., Paudel, A., Paulos, B., Paulucci, L., Pavlovic, Z., Pawloski, G., Payne, D., Pec, V., Peeters, S. J. M., Pennacchio, E., Penzo, A., Peres, O. L. G., Perry, J., Pershey, D., Pessina, G., Petrillo, G., Petta, C., Petti, R., Piastra, F., Pickering, L., Pietropaolo, F., Plunkett, R., Poling, R., Pons, X., Poonthottathil, N., Pordes, S., Porter, J., Potekhin, M., Potenza, R., Potukuchi, B. V. K. S., Pozimski, J., Pozzato, M., Prakash, S., Prakash, T., Prince, S., Pugnere, D., Qian, X., Bazetto, M. C. Queiroga, Raaf, J. L., Radeka, V., Rademacker, J., Radics, B., Rafique, A., Raguzin, E., Rai, M., Rajaoalisoa, M., Rakhno, I., Rakotonandrasana, A., Rakotondravohitra, L., Ramachers, Y. A., Rameika, R., Delgado, M. A. Ramirez, Ramson, B., Rappoldi, A., Raselli, G., Ratoff, P., Raut, S., Razakamiandra, R. F., Real, J. S., Rebel, B., Reggiani-Guzzo, M., Rehak, T., Reichenbacher, J., Reitzner, S. D., Sfar, H. Rejeb, Renshaw, A., Rescia, S., Resnati, F., Reynolds, A., Riccio, C., Riccobene, G., Rice, L. C. J., Ricol, J., Rigamonti, A., Rigaut, Y., Rivera, D., Rochester, L., Roda, M., Rodrigues, P., Alonso, M. J. Rodriguez, Bonilla, E. Rodriguez, Rondon, J. Rodriguez, Rosauro-Alcaraz, S., Rosenberg, M., Rosier, P., Roskovec, B., Rossella, M., Rout, J., Roy, P., Roy, S., Rubbia, A., Rubbia, C., Rubio, F. C., Russell, B., Ruterbories, D., Saakyan, R., Sacerdoti, S., Safford, T., Sahay, R., Sahu, N., Sala, P., Samios, N., Samoylov, O., Sanchez, M. C., Sanders, D. A., Sankey, D., Santana, S., Santos-Maldonado, M., Saoulidou, N., Sapienza, P., Sarasty, C., Sarcevic, I., Savage, G., Savinov, V., Scaramelli, A., Scarff, A., Scarpelli, A., Schaffer, T., Schellman, H., Schlabach, P., Schmitz, D., Scholberg, K., Schukraft, A., Segreto, E., Sensenig, J., Seong, I., Sergi, A., Sgalaberna, D., Shaevitz, M. H., Shafaq, S., Shamma, M., Sharankova, R., Sharma, H. R., Sharma, R., Kumar, R., Shaw, T., Shepherd-Themistocleous, C., Shin, S., Shooltz, D., Shrock, R., Simard, L., Simon, F., Simos, N., Sinclair, J., Sinev, G., Singh, J., Singh, V., Sipos, R., Sippach, F. W., Sirri, G., Sitraka, A., Siyeon, K., VIII, K. Skarpaas, Smith, A., Smith, E., Smith, P., Smolik, J., Smy, M., Snider, E. L., Snopok, P., Nunes, M. Soares, Sobel, H., Soderberg, M., Salinas, C. J. Solano, Söldner-Rembold, S., Solomey, N., Solovov, V., Sondheim, W. E., Sorel, M., Soto-Oton, J., Sousa, A., Soustruznik, K., Spagliardi, F., Spanu, M., Spitz, J., Spooner, N. J. C., Spurgeon, K., Staley, R., Stancari, M., Stanco, L., Stanley, R., Stein, R., Steiner, H. M., Stewart, J., Stillwell, B., Stock, J., Stocker, F., Stokes, T., Strait, M., Strauss, T., Striganov, S., Stuart, A., Suarez, J. G., Sullivan, H., Summers, D., Surdo, A., Susic, V., Suter, L., Sutera, C. M., Svoboda, R., Szczerbinska, B., Szelc, A. M., Talaga, R., Tanaka, H. A., Oregui, B. Tapia, Tapper, A., Tariq, S., Tatar, E., Tayloe, R., Teklu, A. M., Tenti, M., Terao, K., Ternes, C. A., Terranova, F., Testera, G., Thea, A., Thompson, J. L., Thorn, C., Timm, S. C., Todd, J., Tonazzo, A., Torbunov, D., Torti, M., Tortola, M., Tortorici, F., Totani, D., Toups, M., Touramanis, C., Trevor, J., Trilov, S., Trzaska, W. H., Tsai, Y. T., Tsamalaidze, Z., Tsang, K. V., Tsverava, N., Tufanli, S., Tull, C., Tyley, E., Tzanov, M., Uchida, M. A., Urheim, J., Usher, T., Uzunyan, S., Vagins, M. R., Vahle, P., Valdiviesso, G. A., Valencia, E., Vallari, Z., Valle, J. W. F., Vallecorsa, S., Van Berg, R., Van de Water, R. G., Varanini, F., Vargas, D., Varner, G., Vasel, J., Vasina, S., Vasseur, G., Vaughan, N., Vaziri, K., Ventura, S., Verdugo, A., Vergani, S., Vermeulen, M. A., Verzocchi, M., Vicenzi, M., de Souza, H. Vieira, Vignoli, C., Vilela, C., Viren, B., Vrba, T., Wachala, T., Waldron, A. V., Wallbank, M., Wang, H., Wang, J., Wang, M. H. L. S., Wang, Y., Warburton, K., Warner, D., Wascko, M., Waters, D., Watson, A., Weatherly, P., Weber, A., Weber, M., Wei, H., Weinstein, A., Wenman, D., Wetstein, M., White, A., Whitehead, L. H., Whittington, D., Wilking, M. J., Wilkinson, C., Williams, Z., Wilson, F., Wilson, R. J., Wolcott, J., Wongjirad, T., Wood, A., Wood, K., Worcester, E., Worcester, M., Wret, C., Wu, W., Xiao, Y., Yandel, E., Yang, G., Yang, K., Yang, S., Yang, T., Yankelevich, A., Yershov, N., Yonehara, K., Young, T., Yu, B., Yu, H., Yu, J., Yuan, W., Zaki, R., Zalesak, J., Zambelli, L., Zamorano, B., Zani, A., Zazueta, L., Zeit, G., Zeller, G. P., Zennamo, J., Zeug, K., Zhang, C., Zhao, M., Zhivun, E., Zhu, G., Zilberman, P., Zimmerman, E. D., Zito, M., Zucchelli, S., Zuklin, J., Zutshi, V., and Zwaska, R.

Subjects
Physics - Instrumentation and Detectors, High Energy Physics - Experiment
Abstract

This report describes the conceptual design of the DUNE near detector, Comment: 314 pages, 185 figures

Published
2021

241. Determining the Neutrino Mass Ordering and Oscillation Parameters with KM3NeT/ORCA

Author

Aiello, S., Albert, A., Garre, S. Alves, Aly, Z., Ambrosone, A., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Ardid, S., Aublin, J., Bagatelas, C., Baret, B., Pree, S. Basegmez du, Bendahman, M., Benfenati, F., Berbee, E., Berg, A. M. van den, Bertin, V., Biagi, S., Bissinger, M., Boettcher, M., Cabo, M. Bou, Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Brânzaş, H., Bruijn, R., Brunner, J., Bruno, R., Buis, E., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Capone, A., Carretero, V., Castaldi, P., Celli, S., Chabab, M., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Molla, M. Colomer, Coniglione, R., Coyle, P., Creusot, A., Cruz, A., Cuttone, G., Dallier, R., De Martino, B., De Palma, M., Di Marino, M., Di Palma, I., Díaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dornic, D., Dörr, M., Drouhin, D., Eberl, T., Eddyamoui, A., van Eeden, T., van Eijk, D., Bojaddaini, I. El, Elsaesser, D., Enzenhöfer, A., Espinosa, V., Fermani, P., Ferrara, G., Filipovic, M. D., Filippini, F., Fusco, L. A., Gal, T., Soto, A. Garcia, Garufi, F., Gatelet, Y., Geisselbrecht, N., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grasso, D., Grella, G., Guderian, D., Guidi, C., Haefner, J., Hallmann, S., Hamdaoui, H., van Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Hernández-Rey, J. J., Hofestädt, J., Huang, F., Ibnsalih, W. Idrissi, Illuminati, G., James, C. W., de Jong, M., de Jong, P., Jung, B. J., Kadler, M., Kalaczyński, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. Khan, Kistauri, G., van der Knaap, F., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Lahmann, R., Lamoureux, M., Larosa, G., Lastoria, C., Breton, R. Le, Stum, S. Le, Leonardi, O., Leone, F., Leonora, E., Lessing, N., Levi, G., Lincetto, M., Clark, M. Lindsey, Lipreau, T., Longhitano, F., Lopez-Coto, D., Maderer, L., Mańczak, J., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martínez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Melis, K. W., Miele, G., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Morganti, M., Moser, M., Moussa, A., Muller, R., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Fearraigh, B. Ó, O'Sullivan, M., Organokov, M., Orlando, A., González, J. Palacios, Papalashvili, G., Papaleo, R., Pastore, C., Păun, A. M., Păvălaş, G. E., Pellegrino, C., Perrin-Terrin, M., Pestel, V., Piattelli, P., Pieterse, C., Pikounis, K., Pisanti, O., Poirè, C., Popa, V., Pradier, T., Pühlhofer, G., Pulvirenti, S., Rabyang, O., Raffaelli, F., Randazzo, N., Razzaque, S., Real, D., Reck, S., Riccobene, G., Romanov, A., Rovelli, A., Greus, F. Salesa, Samtleben, D. F. E., Losa, A. Sánchez, Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schnabel, J., Schneider, M. F., Schumann, J., Schutte, H. M., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Stellacci, S. M., Taiuti, M., Tayalati, Y., Tenllado, E., Thiersen, H., Tingay, S., Tsourapis, V., Tzamariudaki, E., Tzanetatos, D., Van Elewyck, V., Vasileiadis, G., Versari, F., Vivolo, D., de Wasseige, G., Wilms, J., Wojaczyński, R., de Wolf, E., Yousfi, T., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zúñiga, J., and Zywucka, N.

Subjects
High Energy Physics - Experiment
Abstract

The next generation of water Cherenkov neutrino telescopes in the Mediterranean Sea are under construction offshore France (KM3NeT/ORCA) and Sicily (KM3NeT/ARCA). The KM3NeT/ORCA detector features an energy detection threshold which allows to collect atmospheric neutrinos to study flavour oscillation. This paper reports the KM3NeT/ORCA sensitivity to this phenomenon. The event reconstruction, selection and classification are described. The sensitivity to determine the neutrino mass ordering was evaluated and found to be 4.4 $\sigma$ if the true ordering is normal and 2.3 $\sigma$ if inverted, after three years of data taking. The precision to measure $\Delta m^2_{32}$ and $\theta_{23}$ were also estimated and found to be $85\cdot10^{-6}$ eV$^2$ and $(^{+1.9}_{-3.1})^{\circ}$ for normal neutrino mass ordering and, $75\cdot10^{-6}$ eV$^2$ and $(^{+2.0}_{-7.0})^{\circ}$ for inverted ordering. Finally, a unitarity test of the leptonic mixing matrix by measuring the rate of tau neutrinos is described. Three years of data taking were found to be sufficient to exclude $\nu_{\tau}$ and $\bar{\nu}_{\tau}$ event rate variations larger than 20% at $3\sigma$ level., Comment: Accepted for publication at EPJ-C

Published
2021
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242. X-ray emitting structures in the Vela SNR: ejecta anisotropies and progenitor stellar wind residuals

Author

Sapienza, Vincenzo, Miceli, Marco, Peres, Giovanni, Bocchino, Fabrizio, Orlando, Salvatore, Greco, Emanuele, Combi, Jorge Ariel, García, Federico, and Sasaki, Manami

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The Vela supernova remnant (SNR) shows several ejecta fragments protruding beyond the forward shock (shrapnel). Recent studies have revealed high Si abundance in two shrapnel (A and G), located in opposite directions with respect to the SNR center. This suggests the possible existence of a Si-rich jet-counterjet structure. We analyzed an XMM-Newton observation of a bright clump, behind shrapnel G, which lies along the direction connecting A and G. The aim is to study the physical and chemical properties of this clump to ascertain whether it is part of this putative jet-like structure. We produced background-corrected and adaptively-smoothed count-rate images and median photon energy maps, and performed a spatially resolved spectral analysis. We identified two structures with different physical properties. The first one is remarkably elongated along the direction connecting A and G. Its X-ray spectrum is much softer than that of the other two shrapnel, to the point of hindering the determination of the Si abundance, however its physical and chemical properties are consistent with those of shrapnel A and G. The second structure, running along the southeast-northwest direction, has a higher temperature and appears like a thin filament. By analyzing the ROSAT data, we have found that this filament is part of a very large and coherent structure that we identified in the western rim of the shell. We obtained a thorough description of the tail of Shrapnel G. In addition we discovered a coherent and very extended feature that we interpret as a signature of an earlier interaction of the remnant with the stellar wind of its progenitor star. The peculiar Ne/O ratio we found in the wind residual may be suggestive of a Wolf-Rayet progenitor for Vela SNR, though further analysis is required to address this point., Comment: 10 pages, 13 figures, Accepted to A&A

Published
2021
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243. Experiment Simulation Configurations Approximating DUNE TDR

Author

DUNE Collaboration, Abi, B., Acciarri, R., Acero, M. A., Adamov, G., Adams, D., Adinolfi, M., Ahmad, Z., Ahmed, J., Alion, T., Monsalve, S. Alonso, Alt, C., Anderson, J., Andreopoulos, C., Andrews, M. P., Andrianala, F., Andringa, S., Ankowski, A., Antonova, M., Antusch, S., Aranda-Fernandez, A., Ariga, A., Arnold, L. O., Arroyave, M. A., Asaadi, J., Aurisano, A., Aushev, V., Autiero, D., Azfar, F., Back, H., Back, J. J., Backhouse, C., Baesso, P., Bagby, L., Bajou, R., Balasubramanian, S., Baldi, P., Bambah, B., Barao, F., Barenboim, G., Barker, G. J., Barkhouse, W., Barnes, C., Barr, G., Monarca, J. Barranco, Barros, N., Barrow, J. L., Bashyal, A., Basque, V., Bay, F., Alba, J. L. Bazo, Beacom, J. F., Bechetoille, E., Behera, B., Bellantoni, L., Bellettini, G., Bellini, V., Beltramello, O., Belver, D., Benekos, N., Neves, F. Bento, Berger, J., Berkman, S., Bernardini, P., Berner, R. M., Berns, H., Bertolucci, S., Betancourt, M., Bezawada, Y., Bhattacharjee, M., Bhuyan, B., Biagi, S., Bian, J., Biassoni, M., Biery, K., Bilki, B., Bishai, M., Bitadze, A., Blake, A., Siffert, B. Blanco, Blaszczyk, F. D. M., Blazey, G. C., Blucher, E., Boissevain, J., Bolognesi, S., Bolton, T., Bonesini, M., Bongrand, M., Bonini, F., Booth, A., Booth, C., Bordoni, S., Borkum, A., Boschi, T., Bostan, N., Bour, P., Boyd, S. B., Boyden, D., Bracinik, J., Braga, D., Brailsford, D., Brandt, A., Bremer, J., Brew, C., Brianne, E., Brice, S. J., Brizzolari, C., Bromberg, C., Brooijmans, G., Brooke, J., Bross, A., Brunetti, G., Buchanan, N., Budd, H., Caiulo, D., Calafiura, P., Calcutt, J., Calin, M., Calvez, S., Calvo, E., Camilleri, L., Caminata, A., Campanelli, M., Caratelli, D., Carini, G., Carlus, B., Carniti, P., Terrazas, I. Caro, Carranza, H., Castillo, A., Castromonte, C., Cattadori, C., Cavalier, F., Cavanna, F., Centro, S., Cerati, G., Cervelli, A., Villanueva, A. Cervera, Chalifour, M., Chang, C., Chardonnet, E., Chatterjee, A., Chattopadhyay, S., Chaves, J., Chen, H., Chen, M., Chen, Y., Cherdack, D., Chi, C., Childress, S., Chiriacescu, A., Cho, K., Choubey, S., Christensen, A., Christian, D., Christodoulou, G., Church, E., Clarke, P., Coan, T. E., Cocco, A. G., Coelho, J. A. B., Conley, E., Conrad, J. M., Convery, M., Corwin, L., Cotte, P., Cremaldi, L., Cremonesi, L., Crespo-Anadón, J. I., Cristaldo, E., Cross, R., Cuesta, C., Cui, Y., Cussans, D., Dabrowski, M., da Motta, H., Peres, L. Da Silva, David, C., David, Q., Davies, G. S., Davini, S., Dawson, J., De, K., De Almeida, R. M., Debbins, P., De Bonis, I., Decowski, M. P., de Gouvêa, A., De Holanda, P. C., Astiz, I. L. De Icaza, Deisting, A., De Jong, P., Delbart, A., Delepine, D., Delgado, M., Dell'Acqua, A., De Lurgio, P., Neto, J. R. T. de Mello, DeMuth, D. M., Dennis, S., Densham, C., Deptuch, G., De Roeck, A., De Romeri, V., De Vries, J. J., Dharmapalan, R., Dias, M., Diaz, F., Díaz, J. S., Di Domizio, S., Di Giulio, L., Ding, P., Di Noto, L., Distefano, C., Diurba, R., Diwan, M., Djurcic, Z., Dokania, N., Dolinski, M. J., Domine, L., Douglas, D., Drielsma, F., Duchesneau, D., Duffy, K., Dunne, P., Durkin, T., Duyang, H., Dvornikov, O., Dwyer, D. A., Dyshkant, A. S., Eads, M., Edmunds, D., Eisch, J., Emery, S., Ereditato, A., Escobar, C. O., Sanchez, L. Escudero, Evans, J. J., Ewart, E., Ezeribe, A. C., Fahey, K., Falcone, A., Farnese, C., Farzan, Y., Felix, J., Fernandez-Martinez, E., Menendez, P. Fernandez, Ferraro, F., Fields, L., Filkins, A., Filthaut, F., Fitzpatrick, R. S., Flanagan, W., Fleming, B., Flight, R., Fowler, J., Fox, W., Franc, J., Francis, K., Franco, D., Freeman, J., Freestone, J., Fried, J., Friedland, A., Fuess, S., Furic, I., Furmanski, A. P., Gago, A., Gallagher, H., Gallego-Ros, A., Gallice, N., Galymov, V., Gamberini, E., Gamble, T., Gandhi, R., Gandrajula, R., Gao, S., Garcia-Gamez, D., García-Peris, M. Á., Gardiner, S., Gastler, D., Ge, G., Gelli, B., Gendotti, A., Gent, S., Ghorbani-Moghaddam, Z., Gibin, D., Gil-Botella, I., Girerd, C., Giri, A. K., Gnani, D., Gogota, O., Gold, M., Gollapinni, S., Gollwitzer, K., Gomes, R. A., Bermeo, L. V. Gomez, Fajardo, L. S. Gomez, Gonnella, F., Gonzalez-Cuevas, J. A., Goodman, M. C., Goodwin, O., Goswami, S., Gotti, C., Goudzovski, E., Grace, C., Graham, M., Gramellini, E., Gran, R., Granados, E., Grant, A., Grant, C., Gratieri, D., Green, P., Green, S., Greenler, L., Greenwood, M., Greer, J., Griffith, W. C., Groh, M., Grudzinski, J., Grzelak, K., Gu, W., Guarino, V., Guenette, R., Guglielmi, A., Guo, B., Guthikonda, K. K., Gutierrez, R., Guzowski, P., Guzzo, M. M., Gwon, S., Habig, A., Hackenburg, A., Hadavand, H., Haenni, R., Hahn, A., Haigh, J., Haiston, J., Hamernik, T., Hamilton, P., Han, J., Harder, K., Harris, D. A., Hartnell, J., Hasegawa, T., Hatcher, R., Hazen, E., Heavey, A., Heeger, K. M., Heise, J., Hennessy, K., Henry, S., Morquecho, M. A. Hernandez, Herner, K., Hertel, L., Hesam, A. S., Hewes, V, Higuera, A., Hill, T., Hillier, S. J., Himmel, A., Hoff, J., Hohl, C., Holin, A., Hoppe, E., Horton-Smith, G. A., Hostert, M., Hourlier, A., Howard, B., Howell, R., Huang, J., Hugon, J., Iles, G., Ilic, N., Iliescu, A. M., Illingworth, R., Ioannisian, A., Itay, R., Izmaylov, A., James, E., Jargowsky, B., Jediny, F., Jesùs-Valls, C., Ji, X., Jiang, L., Jiménez, S., Jipa, A., Joglekar, A., Johnson, C., Johnson, R., Jones, B., Jones, S., Jung, C. K., Junk, T., Jwa, Y., Kabirnezhad, M., Kaboth, A., Kadenko, I., Kamiya, F., Karagiorgi, G., Karcher, A., Karolak, M., Karyotakis, Y., Kasai, S., Kasetti, S. P., Kashur, L., Kazaryan, N., Kearns, E., Keener, P., Kelly, K. J., Kemp, E., Ketchum, W., Kettell, S. H., Khabibullin, M., Khotjantsev, A., Khvedelidze, A., Kim, D., King, B., Kirby, B., Kirby, M., Klein, J., Koehler, K., Koerner, L. W., Kohn, S., Koller, P. P., Kordosky, M., Kosc, T., Kose, U., Kostelecký, V. A., Kothekar, K., Krennrich, F., Kreslo, I., Kudenko, Y., Kudryavtsev, V. A., Kulagin, S., Kumar, J., Kumar, R., Kuruppu, C., Kus, V., Kutter, T., Lambert, A., Lande, K., Lane, C. E., Lang, K., Langford, T., Lasorak, P., Last, D., Lastoria, C., Laundrie, A., Lawrence, A., Lazanu, I., LaZur, R., Le, T., Learned, J., LeBrun, P., Miotto, G. Lehmann, Lehnert, R., de Oliveira, M. A. Leigui, Leitner, M., Leyton, M., Li, L., Li, S., Li, S. W., Li, T., Li, Y., Liao, H., Lin, C. S., Lin, S., Lister, A., Littlejohn, B. R., Liu, J., Lockwitz, S., Loew, T., Lokajicek, M., Lomidze, I., Long, K., Loo, K., Lorca, D., Lord, T., LoSecco, J. M., Louis, W. C., Luk, K. B., Luo, X., Lurkin, N., Lux, T., Luzio, V. P., MacFarland, D., Machado, A. A., Machado, P., Macias, C. T., Macier, J. R., Maddalena, A., Madigan, P., Magill, S., Mahn, K., Maio, A., Maloney, J. A., Mandrioli, G., Maneira, J., Manenti, L., Manly, S., Mann, A., Manolopoulos, K., Plata, M. Manrique, Marchionni, A., Marciano, W., Marfatia, D., Mariani, C., Maricic, J., Marinho, F., Marino, A. D., Marshak, M., Marshall, C., Marshall, J., Marteau, J., Martin-Albo, J., Martinez, N., Caicedo, D. A. Martinez, Martynenko, S., Mason, K., Mastbaum, A., Masud, M., Matsuno, S., Matthews, J., Mauger, C., Mauri, N., Mavrokoridis, K., Mazza, R., Mazzacane, A., Mazzucato, E., McCluskey, E., McConkey, N., McFarland, K. S., McGrew, C., McNab, A., Mefodiev, A., Mehta, P., Melas, P., Mellinato, M., Mena, O., Menary, S., Mendez, H., Menegolli, A., Meng, G., Messier, M. D., Metcalf, W., Mewes, M., Meyer, H., Miao, T., Michna, G., Miedema, T., Migenda, J., Milincic, R., Miller, W., Mills, J., Milne, C., Mineev, O., Miranda, O. G., Miryala, S., Mishra, C. S., Mishra, S. R., Mislivec, A., Mladenov, D., Mocioiu, I., Moffat, K., Moggi, N., Mohanta, R., Mohayai, T. A., Mokhov, N., Molina, J., Bueno, L. Molina, Montanari, A., Montanari, C., Montanari, D., Zetina, L. M. Montano, Moon, J., Mooney, M., Moor, A., Moreno, D., Morgan, B., Morris, C., Mossey, C., Motuk, E., Moura, C. A., Mousseau, J., Mu, W., Mualem, L., Mueller, J., Muether, M., Mufson, S., Muheim, F., Muir, A., Mulhearn, M., Muramatsu, H., Murphy, S., Musser, J., Nachtman, J., Nagu, S., Nalbandyan, M., Nandakumar, R., Naples, D., Narita, S., Navas-Nicolás, D., Nayak, N., Nebot-Guinot, M., Necib, L., Negishi, K., Nelson, J. K., Nesbit, J., Nessi, M., Newbold, D., Newcomer, M., Newhart, D., Nichol, R., Niner, E., Nishimura, K., Norman, A., Norrick, A., Northrop, R., Novella, P., Nowak, J. A., Oberling, M., Del Campo, A. Olivares, Olivier, A., Onel, Y., Onishchuk, Y., Ott, J., Pagani, L., Pakvasa, S., Palamara, O., Palestini, S., Paley, J. M., Pallavicini, M., Palomares, C., Pantic, E., Paolone, V., Papadimitriou, V., Papaleo, R., Papanestis, A., Paramesvaran, S., Parke, S., Parsa, Z., Parvu, M., Pascoli, S., Pasqualini, L., Pasternak, J., Pater, J., Patrick, C., Patrizii, L., Patterson, R. B., Patton, S. J., Patzak, T., Paudel, A., Paulos, B., Paulucci, L., Pavlovic, Z., Pawloski, G., Payne, D., Pec, V., Peeters, S. J. M., Penichot, Y., Pennacchio, E., Penzo, A., Peres, O. L. G., Perry, J., Pershey, D., Pessina, G., Petrillo, G., Petta, C., Petti, R., Piastra, F., Pickering, L., Pietropaolo, F., Pillow, J., Pinzino, J., Plunkett, R., Poling, R., Pons, X., Poonthottathil, N., Pordes, S., Potekhin, M., Potenza, R., Potukuchi, B. V. K. S., Pozimski, J., Pozzato, M., Prakash, S., Prakash, T., Prince, S., Prior, G., Pugnere, D., Qi, K., Qian, X., Raaf, J. L., Raboanary, R., Radeka, V., Rademacker, J., Radics, B., Rafique, A., Raguzin, E., Rai, M., Rajaoalisoa, M., Rakhno, I., Rakotondramanana, H. T., Rakotondravohitra, L., Ramachers, Y. A., Rameika, R., Delgado, M. A. Ramirez, Ramson, B., Rappoldi, A., Raselli, G., Ratoff, P., Ravat, S., Razafinime, H., Real, J. S., Rebel, B., Redondo, D., Reggiani-Guzzo, M., Rehak, T., Reichenbacher, J., Reitzner, S. D., Renshaw, A., Rescia, S., Resnati, F., Reynolds, A., Riccobene, G., Rice, L. C. J., Rielage, K., Rigaut, Y., Rivera, D., Rochester, L., Roda, M., Rodrigues, P., Alonso, M. J. Rodriguez, Rondon, J. Rodriguez, Roeth, A. J., Rogers, H., Rosauro-Alcaraz, S., Rossella, M., Rout, J., Roy, S., Rubbia, A., Rubbia, C., Russell, B., Russell, J., Ruterbories, D., Saakyan, R., Sacerdoti, S., Safford, T., Sahu, N., Sala, P., Samios, N., Sanchez, M. C., Sanders, D. A., Sankey, D., Santana, S., Santos-Maldonado, M., Saoulidou, N., Sapienza, P., Sarasty, C., Sarcevic, I., Savage, G., Savinov, V., Scaramelli, A., Scarff, A., Scarpelli, A., Schaffer, T., Schellman, H., Schlabach, P., Schmitz, D., Scholberg, K., Schukraft, A., Segreto, E., Sensenig, J., Seong, I., Sergi, A., Sergiampietri, F., Sgalaberna, D., Shaevitz, M. H., Shafaq, S., Shamma, M., Sharma, H. R., Sharma, R., Shaw, T., Shepherd-Themistocleous, C., Shin, S., Shooltz, D., Shrock, R., Simard, L., Simos, N., Sinclair, J., Sinev, G., Singh, J., Singh, V., Sipos, R., Sippach, F. W., Sirri, G., Sitraka, A., Siyeon, K., Smargianaki, D., Smith, A., Smith, E., Smith, P., Smolik, J., Smy, M., Snopok, P., Nunes, M. Soares, Sobel, H., Soderberg, M., Salinas, C. J. Solano, Söldner-Rembold, S., Solomey, N., Solovov, V., Sondheim, W. E., Sorel, M., Soto-Oton, J., Sousa, A., Soustruznik, K., Spagliardi, F., Spanu, M., Spitz, J., Spooner, N. J. C., Spurgeon, K., Staley, R., Stancari, M., Stanco, L., Steiner, H. M., Stewart, J., Stillwell, B., Stock, J., Stocker, F., Stokes, T., Strait, M., Strauss, T., Striganov, S., Stuart, A., Summers, D., Surdo, A., Susic, V., Suter, L., Sutera, C. M., Svoboda, R., Szczerbinska, B., Szelc, A. M., Talaga, R., Tanaka, H. A., Oregui, B. Tapia, Tapper, A., Tariq, S., Tatar, E., Tayloe, R., Teklu, A. M., Tenti, M., Terao, K., Ternes, C. A., Terranova, F., Testera, G., Thea, A., Thompson, J. L., Thorn, C., Timm, S. C., Tonazzo, A., Torti, M., Tortola, M., Tortorici, F., Totani, D., Toups, M., Touramanis, C., Trevor, J., Trzaska, W. H., Tsai, Y. T., Tsamalaidze, Z., Tsang, K. V., Tsverava, N., Tufanli, S., Tull, C., Tyley, E., Tzanov, M., Uchida, M. A., Urheim, J., Usher, T., Vagins, M. R., Vahle, P., Valdiviesso, G. A., Valencia, E., Vallari, Z., Valle, J. W. F., Vallecorsa, S., Van Berg, R., Van de Water, R. G., Forero, D. Vanegas, Varanini, F., Vargas, D., Varner, G., Vasel, J., Vasseur, G., Vaziri, K., Ventura, S., Verdugo, A., Vergani, S., Vermeulen, M. A., Verzocchi, M., de Souza, H. Vieira, Vignoli, C., Vilela, C., Viren, B., Vrba, T., Wachala, T., Waldron, A. V., Wallbank, M., Wang, H., Wang, J., Wang, Y., Warburton, K., Warner, D., Wascko, M., Waters, D., Watson, A., Weatherly, P., Weber, A., Weber, M., Wei, H., Weinstein, A., Wenman, D., Wetstein, M., While, M. R., White, A., Whitehead, L. H., Whittington, D., Wilking, M. J., Wilkinson, C., Williams, Z., Wilson, F., Wilson, R. J., Wolcott, J., Wongjirad, T., Wood, K., Wood, L., Worcester, E., Worcester, M., Wret, C., Wu, W., Xiao, Y., Yang, G., Yang, T., Yershov, N., Yonehara, K., Young, T., Yu, B., Yu, J., Zaki, R., Zalesak, J., Zambelli, L., Zamorano, B., Zani, A., Zazueta, L., Zeller, G. P., Zennamo, J., Zeug, K., Zhang, C., Zhao, M., Zhivun, E., Zhu, G., Zimmerman, E. D., Zito, M., Zucchelli, S., Zuklin, J., Zutshi, V., and Zwaska, R.

Subjects
High Energy Physics - Experiment, High Energy Physics - Phenomenology
Abstract

The Deep Underground Neutrino Experiment (DUNE) is a next-generation long-baseline neutrino oscillation experiment consisting of a high-power, broadband neutrino beam, a highly capable near detector located on site at Fermilab, in Batavia, Illinois, and a massive liquid argon time projection chamber (LArTPC) far detector located at the 4850L of Sanford Underground Research Facility in Lead, South Dakota. The long-baseline physics sensitivity calculations presented in the DUNE Physics TDR, and in a related physics paper, rely upon simulation of the neutrino beam line, simulation of neutrino interactions in the near and far detectors, fully automated event reconstruction and neutrino classification, and detailed implementation of systematic uncertainties. The purpose of this posting is to provide a simplified summary of the simulations that went into this analysis to the community, in order to facilitate phenomenological studies of long-baseline oscillation at DUNE. Simulated neutrino flux files and a GLoBES configuration describing the far detector reconstruction and selection performance are included as ancillary files to this posting. A simple analysis using these configurations in GLoBES produces sensitivity that is similar, but not identical, to the official DUNE sensitivity. DUNE welcomes those interested in performing phenomenological work as members of the collaboration, but also recognizes the benefit of making these configurations readily available to the wider community., Comment: 15 pages, 6 figures, configurations in ancillary files, v2 corrects a typo

Published
2021

244. The KM3NeT potential for the next core-collapse supernova observation with neutrinos

Author

KM3NeT Collaboration, Aiello, S., Albert, A., Garre, S. Alves, Aly, Z., Ambrosone, A., Ameli, F., Andre, M., Androulakis, G., Anghinolfi, M., Anguita, M., Anton, G., Ardid, M., Ardid, S., Aublin, J., Bagatelas, C., Baret, B., Pree, S. Basegmez du, Bendahman, M., Benfenati, F., Berbee, E., Berg, A. M. van den, Bertin, V., Biagi, S., Bissinger, M., Boettcher, M., Cabo, M. Bou, Boumaaza, J., Bouta, M., Bouwhuis, M., Bozza, C., Brânzaş, H., Bruijn, R., Brunner, J., Buis, E., Buompane, R., Busto, J., Caiffi, B., Calvo, D., Capone, A., Carretero, V., Castaldi, P., Celli, S., Chabab, M., Chau, N., Chen, A., Cherubini, S., Chiarella, V., Chiarusi, T., Circella, M., Cocimano, R., Coelho, J. A. B., Coleiro, A., Molla, M. Colomer, Coniglione, R., Coyle, P., Creusot, A., Cuttone, G., Dallier, R., De Martino, B., De Palma, M., Di Marino, M., Di Palma, I., Dıaz, A. F., Diego-Tortosa, D., Distefano, C., Domi, A., Donzaud, C., Dornic, D., Dörr, M., Drouhin, D., Eberl, T., Eddyamoui, A., van Eeden, T., van Eijk, D., Bojaddaini, I. El, Elsaesser, D., Enzenhöfer, A., Espinosa, V., Fermani, P., Ferrara, G., Filipović, M. D., Filippini, F., Fusco, L. A., Gabella, O., Gal, T., Soto, A. Garcia, Garufi, F., Gatelet, Y., Geißelbrecht, N., Gialanella, L., Giorgio, E., Gozzini, S. R., Gracia, R., Graf, K., Grasso, D., Grella, G., Guderian, D., Guidi, C., Haefner, J., Hamdaoui, H., van Haren, H., Heijboer, A., Hekalo, A., Hennig, L., Hernández-Rey, J. J., Hofestädt, J., Huang, F., Ibnsalih, W. Idrissi, Illuminati, G., James, C. W., de Jong, M., de Jong, P., Jung, B. J., Kadler, M., Kalaczyński, P., Kalekin, O., Katz, U. F., Chowdhury, N. R. Khan, Kistauri, G., van der Knaap, F., Kooijman, P., Kouchner, A., Kreter, M., Kulikovskiy, V., Lahmann, R., Lamoureux, M., Larosa, G., Breton, R. Le, Stum, S. Le, Leonardi, O., Leone, F., Leonora, E., Lessing, N., Levi, G., Lincetto, M., Clark, M. Lindsey, Lipreau, T., Longhitano, F., Lopez-Coto, D., Maderer, L., Mańczak, J., Mannheim, K., Margiotta, A., Marinelli, A., Markou, C., Martin, L., Martınez-Mora, J. A., Martini, A., Marzaioli, F., Mastroianni, S., Mazzou, S., Melis, K. W., Miele, G., Migliozzi, P., Migneco, E., Mijakowski, P., Miranda, L. S., Mollo, C. M., Morganti, M., Moser, M., Moussa, A., Muller, R., Musumeci, M., Nauta, L., Navas, S., Nicolau, C. A., Fearraigh, B. Ó, O'Sullivan, M., Organokov, M., Orlando, A., González, J. Palacios, Papalashvili, G., Papaleo, R., Passaro, G., Pastore, C., Păun, A. M., Păvălaş, G. E., Pellegrino, C., Perrin-Terrin, M., Pestel, V., Piattelli, P., Pieterse, C., Pikounis, K., Pisanti, O., Poirè, C., Popa, V., Pradier, T., Pühlhofer, G., Pulvirenti, S., Rabyang, O., Raffaelli, F., Randazzo, N., Razzaque, S., Real, D., Reck, S., Riccobene, G., Rivoire, S., Romanov, A., Rovelli, A., Greus, F. Salesa, Samtleben, D. F. E., Losa, A. Sánchez, Sanguineti, M., Santangelo, A., Santonocito, D., Sapienza, P., Schnabel, J., Schneider, M. F., Schumann, J., Schutte, H. M., Seneca, J., Sgura, I., Shanidze, R., Sharma, A., Simeone, F., Sinopoulou, A., Spisso, B., Spurio, M., Stavropoulos, D., Stellacci, S. M., Taiuti, M., Tayalati, Y., Tenllado, E., Thakore, T., Thiersen, H., Tingay, S., Tsourapis, V., Tzamariudaki, E., Tzanetatos, D., Unbehaun, T., Van Elewyck, V., Vannoye, G., Vasileiadis, G., Vermariën, G., Versari, F., Viola, S., Vivolo, D., de Wasseige, G., Wilms, J., Wojaczyński, R., de Wolf, E., Zavatarelli, S., Zegarelli, A., Zito, D., Zornoza, J. D., Zúñiga, J., and Zywucka, N.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The KM3NeT research infrastructure is under construction in the Mediterranean Sea. It consists of two water Cherenkov neutrino detectors, ARCA and ORCA, aimed at neutrino astrophysics and oscillation research, respectively. Instrumenting a large volume of sea water with $\sim$ 6,200 optical modules comprising a total of $\sim$ 200,000 photomultiplier tubes, KM3NeT will achieve sensitivity to $\sim$ 10 MeV neutrinos from Galactic and near-Galactic core-collapse supernovae through the observation of coincident hits in photomultipliers above the background. In this paper, the sensitivity of KM3NeT to a supernova explosion is estimated from detailed analyses of background data from the first KM3NeT detection units and simulations of the neutrino signal. The KM3NeT observational horizon (for a $5\,\sigma$ discovery) covers essentially the Milky-Way and for the most optimistic model, extends to the Small Magellanic Cloud ($\sim$ 60 kpc). Detailed studies of the time profile of the neutrino signal allow assessment of the KM3NeT capability to determine the arrival time of the neutrino burst with a few milliseconds precision for sources up to 5$-$8 kpc away, and detecting the peculiar signature of the standing accretion shock instability if the core-collapse supernova explosion happens closer than 3$-$5 kpc, depending on the progenitor mass. KM3NeT's capability to measure the neutrino flux spectral parameters is also presented., Comment: submitted to EPJC

Published
2021
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245. Measurement of the atmospheric $\nu_e$ and $\nu_\mu$ energy spectra with the ANTARES neutrino telescope

Author

Albert, A., Alves, S., André, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -J., Aublin, J., Baret, B., Basa, S., Belhorma, B., Bendahman, M., Bertin, V., Biagi, S., Bissinger, M., Boumaaza, J., Bouta, M., Bouwhuis, M. C., Brânzaş, H., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Carretero, V., Celli, S., Chabab, M., Chau, T. N., Moursli, R. Cherkaoui El, Chiarusi, T., Circella, M., Coleiro, A., Colomer-Molla, M., Coniglione, R., Coyle, P., Creusot, A., Díaz, A. F., de Wasseige, G., Deschamps, A., Distefano, C., Di Palma, I., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., Khayati, N. El, Enzenhöfer, A., Fermani, P., Ferrara, G., Filippini, F., Fusco, L., García, R., Gatelet, Y., Gay, P., Glotin, H., Gozzini, R., Graf, K., Guidi, C., Hallmann, S., van Haren, H., Heijboer, A. J., Hello, Y., Hernández-Rey, J. J., Hößl, J., Hofestädt, J., Huang, F., Illuminati, G., James, C. W., Jisse-Jung, B., de Jong, M., de Jong, P., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Khan-Chowdhury, N. R., Kouchner, A., Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Breton, R. Le, Lefèvre, D., Leonora, E., Levi, G., Lincetto, M., Lopez-Coto, D., Loucatos, S., Maderer, L., Manczak, J., Marcelin, M., Margiotta, A., Marinelli, A., Martínez-Mora, J. A., Melis, K., Migliozzi, P., Moser, M., Moussa, A., Muller, R., Nauta, L., Navas, S., Nezri, E., Nunez-Castineyra, A., O'Fearraigh, B., Organokov, M., Pă, G. E., vă, laş, Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pieterse, C., Poirè, C., Popa, V., Pradier, T., Randazzo, N., Reck, S., Riccobene, G., Greus, F. Salesa, Samtleben, D. F. E., Sánchez-Losa, A., Sanguineti, M., Sapienza, P., Schnabel, J., Schumann, J., Schüssler, F., Spurio, M., Stolarczyk, Th., Taiuti, M., Tayalati, Y., Thakore, T., Tingay, S. J., Vallage, B., Van Elewyck, V., Versari, F., Viola, S., Vivolo, D., Wilms, J., Zegarelli, A., Zornoza, J. D., and Zúniga, J.

Subjects
High Energy Physics - Experiment, Astrophysics - High Energy Astrophysical Phenomena
Abstract

This letter presents a combined measurement of the energy spectra of atmospheric $\nu_e$ and $\nu_\mu$ in the energy range between $\sim$100 GeV and $\sim$50 TeV with the ANTARES neutrino telescope. The analysis uses 3012 days of detector livetime in the period 2007--2017, and selects 1016 neutrinos interacting in (or close to) the instrumented volume of the detector, yielding shower-like events (mainly from $\nu_e+\overline \nu_e$ charged current plus all neutrino neutral current interactions) and starting track events (mainly from $\nu_\mu + \overline \nu_\mu$ charged current interactions). The contamination by atmospheric muons in the final sample is suppressed at the level of a few per mill by different steps in the selection analysis, including a Boosted Decision Tree classifier. The distribution of reconstructed events is unfolded in terms of electron and muon neutrino fluxes. The derived energy spectra are compared with previous measurements that, above 100 GeV, are limited to experiments in polar ice and, for $\nu_\mu$, to Super-Kamiokande., Comment: Accepted to PLB

Published
2021
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246. Open Reduction and Internal Fixation with Plate and Screw versus Triplanar External Fixation in the Surgical Treatment of Calcaneal Fractures: A Retrospective Cohort Study

Author

Vito Pavone, Marco Sapienza, Michela Carnazza, Marco Simone Vaccalluzzo, Giulia Leotta, Francesco Sergi, Giuseppe Mobilia, Danilo Di Via, and Gianluca Testa

Subjects
calcaneal fractures, external fixator, MIOS technique, plate and screw, retrospective cohort study, Medicine
Abstract

Background: The treatment of displaced intra-articular calcaneal fractures (DIACF) is debated. This study compares open reduction and internal fixation (ORIF) with minimally invasive osteosynthesis (MIOS). Methods: We conducted a retrospective study on 70 patients with DIACF treated between January 2018 and September 2022, divided into ORIF (n = 50) and MIOS (n = 20) groups. Functional outcomes were assessed using the Maryland Foot Score (MFS) and the Creighton-Nebraska Health Foundation Assessment Scale (CNHFAS). Radiographic outcomes, complication rates, and reintervention rates were evaluated. A chi-square analysis examined the correlation between Sanders classification and treatment choice. Results: The chi-square analysis indicated no significant correlation between the complexity of the fracture and the type of treatment chosen (χ2 = 0.175, p = 0.916). Additionally, the Cochran–Armitage test for trend showed no significant trend in the choice of treatment based on fracture complexity (statistic = 0.048, p = 0.826). A Kaplan–Meier analysis showed a longer time to reintervention for MIOS (p = 0.029). Complication rates were similar, with specific complications varying between groups. Quality-of-life outcomes were comparable. Conclusions: ORIF is preferable for high-demand patients due to better anatomical outcomes, while MIOS suits high-risk patients by reducing reinterventions and complications. Further randomized trials are needed to confirm these findings.

Published
2024
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247. Fatal Outcome Due to Kounis Syndrome Following Fluorescein Retinal Angiography: A Case Report

Author

Vincenzo Cianci, Claudia Pitrone, Daniela Sapienza, Alessandro Meduri, Antonio Ieni, Patrizia Gualniera, Alessio Asmundo, and Cristina Mondello

Subjects
Kounis syndrome, anaphylaxis, myocardial ischemia, forensic pathology, post mortem biochemistry, post mortem immunohistochemistry, Medicine (General), R5-920
Abstract

Kounis Syndrome (KS) is a clinical entity triggered by allergic or hypersensitivity reactions capable of inducing acute coronary events. Several causes can induce KS, including drugs and insect stings. Here, a rare case of post mortem assessment of fatal KS related to fluorescein retinal angiography has been reported. An 80-year-old man in follow-up for a retinal vein thrombosis underwent a retinal fluoroangiography. Approximately 30 min later, the patient complained of sweating and dizziness, and suddenly lost consciousness due to a cardiac arrest. Despite the immediate cardiopulmonary resuscitation, he died. The autopsy revealed foamy yellowish edema in the respiratory tract and coronary atherosclerosis with eccentric plaques partially obstructing the lumen. The routine histology highlighted lung emphysema and myocyte break-up with foci of contraction band necrosis at the myocardial tissue. Biochemistry showed increased serum tryptase, troponin, and p-BNP. Activated and degranulated (tryptase) mast cells were detected, using immunohistochemistry, in the larynx, lungs, spleen, and heart. Acute myocardial ischemia due to allergic coronary vasospasm related to fluorescein hypersensitivity has been assessed as cause of death. KS-related deaths are considered rare events, and the post mortem assessment of KS quite difficult. The integration of several investigations (gross and microscopic examination, biochemistry, immunohistochemistry) can provide useful findings to support the diagnosis, helping to reduce the unrecognized cases as much as possible.

Published
2024
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248. Allogeneic Stem Cell Transplantation in Refractory Acute Myeloid Leukaemia

Author

Roberto Bono, Giuseppe Sapienza, Stefania Tringali, Cristina Rotolo, Caterina Patti, Antonino Mulè, Valeria Calafiore, Alessandra Santoro, and Luca Castagna

Subjects
refractory acute myeloid leukaemia, allogeneic stem cell transplantation, sequential therapy, myeloablative conditioning regimen, Cytology, QH573-671
Abstract

Refractory acute myeloid leukaemia is very difficult to treat and represents an unmet clinical need. In recent years, new drugs and combinations of drugs have been tested in this category, with encouraging results. However, all treated patients relapsed and died from the disease. The only curative option is allogeneic transplantation through a graft from a healthy donor immune system. Using myeloablative conditioning regimens, the median overall survival regimens is 19%. Several so-called sequential induction chemotherapies followed by allogeneic transplantation conditioned by reduced intensity regimens have been developed, improving the overall survival to 25–57%. In the allogeneic transplantation field, continuous improvements in practices, particularly regarding graft versus host disease prevention, infection prevention, and treatment, have allowed us to observe improvements in survival rates. This is true mainly for patients in complete remission before transplantation and less so for refractory patients. However, full myeloablative regimens are toxic and carry a high risk of treatment-related mortality. In this review, we describe the results obtained with the different modalities used in more recent retrospective and prospective studies. Based on these findings, we speculate how allogeneic stem cell transplantation could be modified to maximise its therapeutic effect on refractory acute myeloid leukaemia.

Published
2024
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249. ANTARES search for point-sources of neutrinos using astrophysical catalogs: a likelihood stacking analysis

Author

Albert, A., André, M., Anghinolfi, M., Anton, G., Ardid, M., Aubert, J. -J., Aublin, J., Baret, B., Basa, S., Belhorma, B., Bertin, V., Biagi, S., Bissinger, M., Boumaaza, J., Bouta, M., Bouwhuis, M. C., Branzas, H., Bruijn, R., Brunner, J., Busto, J., Capone, A., Caramete, L., Carr, J., Carretero, V., Celli, S., Chabab, M., Chau, T. N., Moursli, R., Chiarusi, T., Circella, M., Coleiro, A., Colomer-Molla, M., Coniglione, R., Coyle, P., Creusot, A., Diaz, A. F., de Wasseige, G., Deschamps, A., Distefano, C., di Palma, I., Domi, A., Donzaud, C., Dornic, D., Drouhin, D., Eberl, T., Khayati, N., Enzenhofer, A., Fermani, P., Ferrara, G., Filippini, F., Fusco, L., Gatelet, Y., Gay, P., Glotin, H., Gozzini, R., Gracia, R., Graf, K., Guidi, C., Hallmann, S., Haren, H., Heijboer, A. J., Hello, Y., Hernandez-Rey, J. J., Hössl, J., Hofestädt, J., Huang, F., Illuminati, G., James, C. W., Jisse-Jung, B., Jong, M., Jong, P., Jongen, M., Kadler, M., Kalekin, O., Katz, U., Khan-Chowdhury, N. R., Kouchner, A., Kreykenbohm, I., Kulikovskiy, V., Lahmann, R., Breton, R., Lefèvre, D., Leonora, E., Levi, G., Lincetto, M., Lopez-Coto, D., Loucatos, S., Maderer, L., Manczak, J., Marcelin, M., Margiotta, A., Marinelli, A., Martinez-Mora, J. A., Mazzou, S., Melis, K., Migliozzi, P., Moser, M., Moussa, A., Muller, R., Nauta, L., Navas, S., Nezri, E., Nunez-Castineyra, A., O'Fearraigh, B., Organokov, M., Palavas, G. E., Pellegrino, C., Perrin-Terrin, M., Piattelli, P., Pieterse, C., Poirè, C., Popa, V., Pradier, T., Randazzo, N., Reck, S., Riccobene, G., Greus, F., Samtleben, D. F., Sanchez-Losa, A., Sanguineti, M., Sapienza, P., Schnabel, J., Schussler, F., Spurio, M., Stolarczyk, Th., Taiuti, M., Tayalati, Y., Thakore, T., Tingay, S. J., Vallage, B., Elewyck, V., Versari, F., Viola, S., Vivolo, D., Wilms, J., Zegarelli, A., Zornoza, J. D., Zuniga, J., and Buson, S.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

A search for astrophysical point-like neutrino sources using the data collected by the ANTARES detector between January 29, 2007 and December 31, 2017 is presented. A likelihood stacking method is used to assess the significance of an excess of muon neutrinos inducing track-like events in correlation with the location of a list of possible sources. Different sets of objects are tested in the analysis: a) a sub-sample of the \textit{Fermi} 3LAC catalog of blazars, b) a jet-obscured AGN population, c) a sample of soft gamma-ray selected radio galaxies, d) a star-forming galaxy catalog , and e) a public sample of 56 very-high-energy track events from the IceCube experiment. None of the tested sources shows a significant association with the sample of neutrinos detected by ANTARES. The smallest p-value is obtained for the radio galaxies catalog with an equal weights hypothesis, with a pre-trial p-value equivalent to a $2.8 \, \sigma$ excess, equivalent to $1.6 \, \sigma$ post-trial. In addition, the results of a dedicated analysis for the blazar MG3 J225517+2409 are also reported: this source is found to be the most significant within the \textit{Fermi} 3LAC sample, with 5 ANTARES events located at less than one degree from the source. This blazar showed evidence of flaring activity in \textit{Fermi} data, in space-time coincidence with a high-energy track detected by IceCube. An \emph{a posteriori} significance of $2.0\, \sigma$ for the combination of ANTARES and IceCube data is reported.

Published
2020
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250. Dye stabilization and wavelength tunability in lasing fibers based on DNA

Author

Persano, Luana, Szukalski, Adam, Gaio, Michele, Moffa, Maria, Salvadori, Giacomo, Sznitko, Lech, Camposeo, Andrea, Mysliwiec, Jaroslaw, Sapienza, Riccardo, Mennucci, Benedetta, and Pisignano, Dario

Subjects
Physics - Optics, Condensed Matter - Materials Science
Abstract

Lasers based on biological materials are attracting an increasing interest in view of their use in integrated and transient photonics. DNA as optical biopolymer in combination with highly-emissive dyes has been reported to have excellent potential in this respect, however achieving miniaturized lasing systems based on solid-state DNA shaped in different geometries to confine and enhance emission is still a challenge, and physico-chemical mechanisms originating fluorescence enhancement are not fully understood. Herein, a class of wavelength-tunable lasers based on DNA nanofibers is demonstrated, for which optical properties are highly controlled through the system morphology. A synergistic effect is highlighted at the basis of lasing action. Through a quantum chemical investigation, we show that the interaction of DNA with the encapsulated dye leads to hindered twisting and suppressed channels for the non-radiative decay. This is combined with effective waveguiding, optical gain, and tailored mode confinement to promote morphologically-controlled lasing in DNA-based nanofibers. The results establish design rules for the development of bright and tunable nanolasers and optical networks based on DNA nanostructures., Comment: 31 pages, 11 figures and 2 tables

Published
2020
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