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204. Association of green tea consumption with mortality due to all causes and major causes of death in a Japanese population: the Japan Public Health Center-based Prospective Study (JPHC Study)

Author

Saito, Eiko, primary, Inoue, Manami, additional, Sawada, Norie, additional, Shimazu, Taichi, additional, Yamaji, Taiki, additional, Iwasaki, Motoki, additional, Sasazuki, Shizuka, additional, Noda, Mitsuhiko, additional, Iso, Hiroyasu, additional, Tsugane, Shoichiro, additional, Tsugane, S., additional, Sawada, N., additional, Iwasaki, M., additional, Sasazuki, S., additional, Yamaji, T., additional, Shimazu, T., additional, Hanaoka, T., additional, Ogata, J., additional, Baba, S., additional, Mannami, T., additional, Okayama, A., additional, Kokubo, Y., additional, Miyakawa, K., additional, Saito, F., additional, Koizumi, A., additional, Sano, Y., additional, Hashimoto, I., additional, Ikuta, T., additional, Tanaba, Y., additional, Sato, H., additional, Roppongi, Y., additional, Takashima, T., additional, Miyajima, Y., additional, Suzuki, N., additional, Nagasawa, S., additional, Furusugi, Y., additional, Nagai, N., additional, Ito, Y., additional, Komatsu, S., additional, Minamizono, T., additional, Sanada, H., additional, Hatayama, Y., additional, Kobayashi, F., additional, Uchino, H., additional, Shirai, Y., additional, Kondo, T., additional, Sasaki, R., additional, Watanabe, Y., additional, Miyagawa, Y., additional, Kobayashi, Y., additional, Machida, M., additional, Kobayashi, K., additional, Tsukada, M., additional, Kishimoto, Y., additional, Takara, E., additional, Fukuyama, T., additional, Kinjo, M., additional, Irei, M., additional, Sakiyama, H., additional, Imoto, K., additional, Yazawa, H., additional, Seo, T., additional, Seiko, A., additional, Ito, F., additional, Shoji, F., additional, Saito, R., additional, Murata, A., additional, Minato, K., additional, Motegi, K., additional, Fujieda, T., additional, Yamato, S., additional, Matsui, K., additional, Abe, T., additional, Katagiri, M., additional, Suzuki, M., additional, Doi, M., additional, Terao, A., additional, Ishikawa, Y., additional, Tagami, T., additional, Sueta, H., additional, Doi, H., additional, Urata, M., additional, Okamoto, N., additional, Ide, F., additional, Goto, H., additional, Onga, N., additional, Takaesu, H., additional, Uehara, M., additional, Nakasone, T., additional, Yamakawa, M., additional, Horii, F., additional, Asano, I., additional, Yamaguchi, H., additional, Aoki, K., additional, Maruyama, S., additional, Ichii, M., additional, Takano, M., additional, Tsubono, Y., additional, Suzuki, K., additional, Honda, Y., additional, Yamagishi, K., additional, Sakurai, S., additional, Tsuchiya, N., additional, Kabuto, M., additional, Yamaguchi, M., additional, Matsumura, Y., additional, Sasaki, S., additional, Watanabe, S., additional, Akabane, M., additional, Kadowaki, T., additional, Inoue, M., additional, Noda, M., additional, Mizoue, T., additional, Kawaguchi, Y., additional, Takashima, Y., additional, Yoshida, Y., additional, Nakamura, K., additional, Takachi, R., additional, Ishihara, J., additional, Matsushima, S., additional, Natsukawa, S., additional, Shimizu, H., additional, Sugimura, H., additional, Tominaga, S., additional, Hamajima, N., additional, Iso, H., additional, Sobue, T., additional, Iida, M., additional, Ajiki, W., additional, Ioka, A., additional, Sato, S., additional, Maruyama, E., additional, Konishi, M., additional, Okada, K., additional, Saito, I., additional, Yasuda, N., additional, Kono, S., additional, and Akiba, S., additional

Published
2015
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206. LB01.02

Author

Kario, K., primary, Saito, I., additional, Kushiro, T., additional, Teramukai, S., additional, Tomono, Y., additional, Okuda, Y., additional, and Shimada, K., additional

Published
2015
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207. PP.31.12

Author

Saito, I., primary, Kario, K., additional, Kushiro, T., additional, Teramukai, S., additional, Yaginuma, M., additional, Mori, Y., additional, Okuda, Y., additional, and Shimada, K., additional

Published
2015
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215. Field emission from modified P-doped diamond surfaces with different barrier heights

Author

Kudo, Y., Yamada, T., Yamaguchi, H., Masuzawa, T., Saito, I., Shikata, S.-i., Nebel, C.E., and Publica

Subjects
P-doped diamond, Phosphor-dotierter Diamant, surface termination, field emission, electron affinity, Feldemission, barrier height
Abstract

In this study, the field emission properties of P-doped diamond with various surface treatments were measured in order to understand the effects of surface treatments on the barrier height. The emission properties were acquired for diamond with C-reconstructed, oxidized, and H-plasma treated surfaces. The voltage drop across the vacuum was estimated for each surface, using threshold voltage-anode distance (V-d) measurement. The estimated electric fields near the diamond surface were 4.95, 26.6, and 54.1 V/mm for the C-reconstructed, oxidized, and H-plasma treated surfaces, respectively. The barrier height ratio of these surfaces derived from their electric fields was 1 : 3:1 : 4:9, which agrees with the result derived from Fowler-Nordheim plots. Considering the electron affinities of all surfaces and the obtained results, positive electron affinities dominate the field emission properties of the C-reconstructed and oxidized surfaces. An internal barrier due to upward band bending on the H-plasma treated surface limits the field emission properties, even though it has a negative electron affinity. Our results suggest that the emission properties strongly depend on the barrier height, which is modified by surface treatment.

Published
2008

218. LIST OF CONTRIBUTORS

Author

Alazard, J.P., primary, Amin, S.G., additional, Andrus, A., additional, ApSimon, J.W., additional, Armstrong, V.W., additional, Au-Yeung, B.-W., additional, Avram, M., additional, Ayer, W.A., additional, Babin, D., additional, Backinowsky, L.V., additional, Baldwin, J.E., additional, Bally, I., additional, Balsetan, A.T., additional, Bamezai, S., additional, Bandara, B.M.R., additional, Barth, G., additional, Barton, D.H.R., additional, Beaujean, M., additional, Beeley, N.R.A., additional, Berke, C.M., additional, Besselièvre, R., additional, Betaneli, V.I., additional, Beugelmans, R., additional, Birch, A.J., additional, Bose, A.K., additional, Brambilla, R., additional, Braun-Keller, E., additional, Brown, E., additional, Brownbridge, P., additional, Caspi, E., additional, Chamberlain, K., additional, Chan, T.H., additional, Chauncy, B., additional, Chottard, J.C., additional, Clardy, J., additional, Clark, B.C., additional, Collins, J.B., additional, Coulton, S., additional, Crouse, G.D., additional, Dadoun, H., additional, Dahler, P., additional, Day, A.I., additional, De Ville, G., additional, Dinulescu, I.G., additional, Djerassi, C., additional, von E. Doering, W., additional, Drâghici, C., additional, Elian, M., additional, Factor, R.E., additional, Faulkner, D.J., additional, Fernandez, I.F., additional, Finer-Moore, J., additional, Fleming, I., additional, Florent, J.-C., additional, Fourneron, J.-D., additional, Friary, R., additional, Fuhrer, H., additional, Fukuyama, T., additional, Funke, P.T., additional, Furmanova, N.G., additional, Fürst, A., additional, Furuhata, K., additional, Gala, K., additional, Ganguly, A., additional, Georgescu, E.G., additional, Gheorghiu, M.D., additional, Girard, P., additional, Gneuss, K.D., additional, Greaves, A.M., additional, Grier, D., additional, Gruska, R., additional, Guilhem, J., additional, Hangauer, D.G., additional, Hendrickson, J.B., additional, Hillenbrand, G.F., additional, Holohan, J.J., additional, Huber, C.P., additional, Huffman, J.W., additional, Husson, H.-P., additional, Iacobucci, G.A., additional, Ireland, C., additional, Irwin, A.J., additional, Janousek, Z., additional, Jenkins, I.D., additional, Johnson, M.A., additional, Jones, B.B., additional, Julia, M., additional, Kagan, H.B., additional, Kägi, D., additional, Kalvoda, J., additional, Kapur, J.C., additional, Katritzky, A.R., additional, Kaufmann, H., additional, Kelly, L.P., additional, Khajavi, M.S., additional, Khor, T.-C., additional, Kishi, Y., additional, Kitchin, J.P., additional, Kochetkov, N.K., additional, Kreder, J., additional, Kretschmer, G., additional, Kriemler, H.-P., additional, Ksander, G.M., additional, Kuwano, H., additional, Lansbury, P.T., additional, Lester, D.J., additional, Lewis, M., additional, Ley, S.V., additional, Liepa, A.J., additional, Lindley, M., additional, Lusinchi, X., additional, Mahanty, M.K., additional, Mallion, K.B., additional, Manhas, M.S., additional, Mansuy, D., additional, Mastrocola, A.R., additional, McMurry, J.E., additional, McPhail, A.T., additional, Meerholz, C.A., additional, Merenyi, R., additional, Metlushenko, V.P., additional, Mignani, S., additional, Minkin, V.I., additional, Mohr, P., additional, Monneret, C., additional, Motherwell, W.B., additional, Mukkavilli, L., additional, Müller, G., additional, Müller, M., additional, Mulliez, E., additional, Musser, J.H., additional, Naegeli, P., additional, Nakatsuka, S.-I., additional, Namy, J.L., additional, Narula, A.S., additional, Ogura, H., additional, Olekhnovich, L.P., additional, Onan, K.D., additional, Ovchinnikov, M.V., additional, Papoula, M.T.B., additional, Paquette, L.A., additional, Parker, W.L., additional, Pârvulescu, L., additional, Patel, R.C., additional, Peel, R., additional, Pickett, J.E., additional, Piper, J.U., additional, Puar, M.S., additional, Ragault, M., additional, Ram, B., additional, Ramachandran, P.V., additional, Ramage, R., additional, Ranganathan, D., additional, Ranganathan, S., additional, Rathnum, M.L., additional, Raverty, W.D., additional, Reed, N.V., additional, Rizzardo, E., additional, Roussi, G., additional, Saeedi-Ghomi, M.H., additional, Saito, I., additional, Scheuer, P.J., additional, Schriver, G.W., additional, Schwartz, R.E., additional, Scott, A.I., additional, Sell, C., additional, Sependa, G.J., additional, Shapiro, S., additional, Sing, L.Y., additional, Smith, K.M., additional, Sondheimer, F., additional, Soulié, J., additional, Stanescu, L., additional, Stephenson, G.R., additional, Stiller, K., additional, Streitwieser, A., additional, Sugiura, M., additional, Sum, F.W., additional, Sundararaman, P., additional, Sunday, B.R., additional, Sutherland, J.K., additional, Suzuki, M., additional, Tagle, B., additional, Tamm, Ch., additional, Tho, N.-D., additional, Thomas, E.J., additional, Thompson, D.J., additional, Toczko, G.A., additional, Van Engen, D., additional, van der Veen, J.M., additional, Viehe, H.G., additional, Vincent, J.E., additional, Wasserman, H.H., additional, Watson, W.H., additional, Weiler, L., additional, Wetli, M., additional, Wiley, D.C., additional, Williamson, D.H., additional, Wolff, M.S., additional, Wong, H.N.C., additional, Wright, J.J., additional, Zabel, V., additional, and Zimmerman, H.E., additional

Published
1982
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226. Replication in vitro and cleavage by restriction endonuclease of 5-formyluracil- and 5-hydroxymethyluracil-containing oligonucleotides

Author

Hiroshi Sugiyama, Qiu-Mei Zhang, Shuji Yonei, Katsuhito Kino, Izumi Miyabe, Saito I, and Matsuda S

Subjects
DNA Replication, DNA clamp, Radiological and Ultrasound Technology, biology, Oligonucleotide, DNA polymerase, DNA polymerase II, Oligonucleotides, DNA Restriction Enzymes, Molecular biology, Restriction fragment, DNA Glycosylases, Pentoxyl, Restriction enzyme, Biochemistry, biology.protein, Mutagenesis, Site-Directed, Animals, Radiology, Nuclear Medicine and imaging, DNA polymerase I, Uracil, Base Pairing, N-Glycosyl Hydrolases, Klenow fragment
Abstract

To investigate the biological consequences of 5-formyluracil (5-foU) and 5-hydroxymethyluracil (5-hmU).The authors constructed 22-mer oligonucleotides containing a 5-foU or 5-hmU residue at the same sites. The effects of such modifications on the ability to serve as a template for DNA polymerase and on the cleavage by sequence-specific restriction endonuclease were examined.The Klenow fragment of DNA polymerase I and Thermus thermophilus DNA polymerase read through the sites of 5-foU and 5-hmU in the templates. 5-FoU directed the incorporation of dCMP in addition to dAMP opposite the lesion during DNA synthesis. The DNA polymerases incorporated only dAMP opposite the 5-hmU. The substitution of thymine by 5-foU within the recognition site of the restriction endonucleases HincII and SalI inhibited or prevented the cleavage by the enzymes, whereas the enzymes cleaved the 5-hmU-containing oligonucleotides at the same rate as the T-containing oligonucleotides.These results indicated that the 5-foU-A base pair is less stable than the T-A base pair and that 5-foU can form a base pair with C in addition to A. It was also demonstrated that the oxidation of thymine to 5-hmU does not result in substantial deterioration.

Published
1999

227. Cytokine regulation on the synthesis of nitric oxide in vivo by chronically infected human polymorphonuclear leucocytes

Author

Takeichi, O, Saito, I, Okamoto, Y, Tsurumachi, T, and Saito, T

Subjects
Adult, Male, Granuloma, Neutrophils, Cell Culture Techniques, Nitric Oxide Synthase Type II, Middle Aged, Nitric Oxide, Recombinant Proteins, Chronic Disease, Leukocytes, Mononuclear, Cytokines, Humans, Female, Nitric Oxide Synthase, Fluorescent Antibody Technique, Indirect, Nitrites, Periapical Periodontitis, Research Article
Abstract

To determine if nitric oxide (NO) is produced by chronically infected human polymorphonuclear leucocytes (PMNs) in vivo, inflamed exudates (periapical exudates: PE) collected from periapical periodontitis patients were examined. Cell-free supernatants and cells were separated by centrifugation. Significant levels of nitrite concentrations were observed in the supernatants. The production of inducible NO synthase (iNOS) in highly purified PMNs derived from PEs was then immunocytochemically determined using rabbit anti-human iNOS antiserum. In vitro, human peripheral blood PMNs (PB-PMNs) isolated from patients were cultured with a combination of Esherichia coli-lipopolysaccharide (LPS), recombinant human interferon-gamma (rhIFN-gamma) and/or interleukin-1 beta (rhIL-1 beta). The stimulated PB-PMNs showed steady-state levels of nitrite. The stimulation of LPS, rhIFN-gamma and rhIL-1 beta showed more NO induction than that of LPS with either IFN-gamma or IL-1 beta, suggesting the synergistic effects of cytokines. Cryostat sections of surgically removed periapical tissues were also immunohistochemically examined for iNOS, IFN-gamma and IL-1 beta. Two-colour immunohistochemistry revealed the interaction of iNOS-producing PMNs and IFN-gamma- or IL-1 beta-producing mononuclear cells. On the basis of these data, we concluded that with the stimulation of inflammatory cytokines derived from mononuclear cells, PMNs can spontaneously produce NO at the site of chronic infection. The present studies are consistent with a hypothesis suggesting that PMNs could be regulated and delicately balanced to produce NO by mononuclear cell-derived cytokines in vivo. NO-producing cells may play a pivotal role in chronic inflammation.

Published
1998

231. Extracorporeal dialysis: techniques and adequacy - A

Author

Steckiph, D., primary, Calabrese, G., additional, Bertucci, A., additional, Mazzotta, A., additional, Vagelli, G., additional, Gonella, M., additional, Stamopoulos, D., additional, Manios, E., additional, Papachristos, N., additional, Grapsa, E., additional, Papageorgiou, G., additional, Gogola, V., additional, So, B., additional, Dey, V., additional, Spalding, E. M., additional, Libetta, C., additional, Esposito, P., additional, Margiotta, E., additional, Maffioli, P., additional, Bonaventura, A., additional, Bianchi, L., additional, Romano, D., additional, Rampino, T., additional, De Rosa, G., additional, Mauric, A., additional, Haug, U., additional, Enzinger, G., additional, Kern-Derstvenscheg, E., additional, Sluga, A., additional, Ausserwinkler, C., additional, Beck, W., additional, Rosenkranz, A. R., additional, Maheshwari, V., additional, Haroon, S., additional, Loy, Y., additional, Samavedham, L., additional, Rangaiah, G. P., additional, Lau, T., additional, Mpakirtzi, N., additional, Panagiotou, M., additional, Barbarousi, D., additional, Matsouka, C., additional, Bunani, A. D., additional, Kowalczyk, M., additional, Bartnicki, P., additional, Banach, M., additional, Rysz, J., additional, Lentini, P., additional, Zanoli, L., additional, Granata, A., additional, Contestabile, A., additional, Basso, A., additional, Berlingo, G., additional, Pellanda, V., additional, de Cal, M., additional, Grazia, V., additional, Clementi, A., additional, Insalaco, M., additional, Dell'Aquila, R., additional, Karkar, A., additional, Abdelrahman, M., additional, Martins, A. R., additional, Parreira, L., additional, Duque, A. S., additional, Rodrigues, I., additional, Baffoun, A. B., additional, Youssfi, M. A., additional, Sayeh, A., additional, Beji, M., additional, Ben Khadra, R., additional, Hmida, J., additional, Akazawa, M., additional, Horiuchi, H., additional, Hori, Y., additional, Yamada, A., additional, Satou, H., additional, Odamaki, S., additional, Nakai, S., additional, Satou, K., additional, Aoki, K., additional, Saito, I., additional, Kamijo, Y., additional, Ogata, S., additional, Ishibashi, Y., additional, Basso, F., additional, Wojewodzka-Zelezniakowicz, M., additional, Cruz, D., additional, Giuliani, A., additional, Blanca Martos, L., additional, Piccinni, P., additional, Ronco, C., additional, Potier, J., additional, Queffeulou, G., additional, Bouet, J., additional, Nilsson, A., additional, Sternby, J., additional, Grundstrom, G., additional, Alquist, M., additional, Ferraresi, M., additional, Di Vico, M. C., additional, Vigotti, F. N., additional, Deagostini, M., additional, Scognamiglio, S., additional, Consiglio, V., additional, Clari, R., additional, Moro, I., additional, Mongilardi, E., additional, Piccoli, G. B., additional, Hancock, V., additional, Huang, S., additional, Nilsson Ekdahl, K., additional, Steckiph, D., additional, Baldin, C., additional, Petrarulo, M., additional, Mancuso, D., additional, Inguaggiato, P., additional, Canepari, G., additional, Gigliola, G., additional, Ferrando, C., additional, Meinero, S., additional, Sicuso, C., additional, Pacitti, A., additional, Afentakis, N., additional, Tomo, T., additional, Matsuyama, K., additional, Nakata, T., additional, Ishida, K., additional, Takeno, T., additional, Kadota, J.-i., additional, Minakuchi, J., additional, Kastl, J., additional, Merello, M., additional, Boccato, C., additional, Giordana, G., additional, Mazzone, S., additional, Moscardo, V., additional, Reinhardt, B., additional, Knaup, R., additional, Kruger, W., additional, Tovbin, D., additional, Kim, S., additional, Avnon, L., additional, Zlotnik, M., additional, Storch, S., additional, Umimoto, K., additional, Shimamoto, Y., additional, Suyama, M., additional, Miyata, M., additional, Bosch Benitez-Parodi, E., additional, Baamonde Laborda, E. E., additional, Perez, G., additional, Ramirez, J. I., additional, Ramirez Puga, A., additional, Guerra, R., additional, Garcia Canton, C., additional, Lago Alonso, M. M., additional, Toledo, A., additional, Checa Andres, M. D., additional, Latif, F. E., additional, Mochida, Y., additional, Matsumoto, K., additional, Morita, K., additional, Tsutsumi, D., additional, Ishioka, K., additional, Maesato, K., additional, Oka, M., additional, Moriya, H., additional, Hidaka, S., additional, Ohtake, T., additional, Kobayashi, S., additional, Ficheux, A., additional, Gayrard, N., additional, Duranton, F., additional, Guzman, C., additional, Szwarc, I., additional, Bismuth-Mondolfo, J., additional, Brunet, P., additional, Servel, M.-F., additional, Argiles, A., additional, Tsikliras, N., additional, Mademtzoglou, S., additional, Balaskas, E., additional, Zeid, M., additional, Mostafa, A., additional, Mowafy, M. N., additional, Abdo, E. I., additional, Al Amin, O. M., additional, Ksiazek, A., additional, Zaluska, W., additional, Waniewski, J., additional, Debowska, M., additional, Wojcik-Zaluska, A., additional, Elias, M., additional, Francois, H., additional, Obada, E., additional, Lorenzo, H. K., additional, Charpentier, B., additional, Durrbach, A., additional, Beaudreuil, S., additional, Imamovic, G., additional, Marcelli, D., additional, Bayh, I., additional, Hrvacevic, R., additional, Kapun, S., additional, Grassmann, A., additional, Scatizzi, L., additional, Maslovaric, J., additional, Daelemans, R., additional, Mesens, S., additional, Mohamed, E. A., additional, Wafae, A., additional, Kawtar, H., additional, Mohamed Amine, H., additional, Driss, K., additional, and Mohammed, B., additional

Published
2013
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235. Photoinduced cleavage of single and double stranded DNA at single guanine proximal to target sequence by dibenzoyldiazomethane-ODN conjugate

Author

Kazuhiko Nakatani, Sando, S., and Saito, I.

Subjects
Base Sequence, Diazomethane, Oligodeoxyribonucleotides, Photochemistry, DNA, Single-Stranded, Nucleic Acid Conformation, DNA
Abstract

DBDM-ODN conjugates selectively cleaved single and double stranded DNA at a specific guanine residue proximal to the target sequence upon exposure to 366 nm light.

Published
1997

238. Nontraditional risk factors for coronary heart disease incidence among persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study.

Author

Saito I, Folsom AR, Brancati FL, Duncan BB, Chambless LE, McGovern PG, Saito, I, Folsom, A R, Brancati, F L, Duncan, B B, Chambless, L E, and McGovern, P G

Abstract

Background: Major risk factors explain much of the excess risk for coronary heart disease produced by diabetes, but nontraditional factors may also relate to incident coronary heart disease.Objective: To examine the association of traditional and nontraditional risk factors with incidence of coronary heart disease in adults with diabetes.Design: Prospective cohort study.Setting: The Atherosclerosis Risk in Communities (ARIC) Study.Participants: 1676 middle-aged persons who had diabetes but no history of prevalent coronary heart disease.Measurements: Multiple risk factors were recorded at baseline. Follow-up was from 1987 through 1995.Results: 186 participants developed incident coronary heart disease events during follow-up. As expected, the incidence of coronary heart disease in participants with diabetes was associated positively with traditional risk factors (hypertension, smoking, total cholesterol level, and low high-density lipoprotein [HDL] cholesterol level). After adjustment for sex, age, ethnicity, and ARIC field center, incident coronary heart disease was also significantly associated with waist-to-hip ratio; levels of HDL3 cholesterol, apolipoproteins A-I and B, albumin, fibrinogen, and von Willebrand factor factor VIII activity; and leukocyte count. However, after adjustment for traditional risk factors for coronary heart disease, only levels of albumin, fibrinogen, and von Willebrand factor; factor VIII activity; and leukocyte count remained independently associated with coronary heart disease (P < 0.03). The relative risks associated with the highest compared with lowest groupings of albumin, fibrinogen, factor VIII, and von Willebrand factor values and leukocyte count were 0.64 (95% CI, 0.44 to 0.92), 1.75 (CI, 1.12 to 2.73), 1.58 (CI, 1.02 to 2.42), 1.71 (CI, 1.11 to 2.63), and 1.90 (CI, 1.16 to 3.13), respectively. Adjustment for diabetes treatment status attenuated these associations somewhat.Conclusions: Levels of albumin, fibrinogen, and von Willebrand factor; factor VIII activity; and leukocyte count were predictors of coronary heart disease among persons with diabetes. These associations may reflect 1) the underlying inflammatory reaction or microvascular injury related to atherosclerosis and a tendency toward thrombosis or 2) common antecedents for both diabetes and coronary heart disease. [ABSTRACT FROM AUTHOR]

Published
2000
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