Search

Este artigo é resultado de um estudo planejado e executado a partir das leituras e compreensões realizadas por um participante do Curso MBA em Educação Híbrida, Metodologias Ativas e Gestão da Aprendizagem – UNISC, proposto e executado pelo Centro Universitário União das Américas, UniAmérica, edição 2019-2020. A partir da proposta do Curso foi realizada uma intervenção com um grupo de estudantes de um programa de Pós-Graduação em Educação – PPGEdu, com o objetivo de verificar as condições de aplicabilidade do Trabalho Discente Efetivo (TDE) e da metodologia da Aprendizagem Baseada em Problemas (ABP), considerando tais situações como parte do processo para a melhoria do desempenho acadêmico e profissional em uma universidade comunitária no Sul do Brasil. É objeto deste artigo, também, o reconhecimento do lugar do professor nos processos de ensino e de aprendizagem e dos tipos de melhorias que poderá proporcionar ao desempenho acadêmico dos estudantes do ensino superior com a utilização da metodologia da Aprendizagem Baseada em Problemas. Para tanto, será realizada uma breve fundamentação teórica a propósito dos termos capitais deste estudo e, na sequência, serão apresentados os problemas e as respostas elaboradas pelos estudantes. Como resultados, ressalta-se que a metodologia da ABP favorece a realização de atividades extraclasse que podem ser consideradas como TDE.

Propomos aqui a elaboração de material didático sobre o conceito de calor para a aplicação na educação básica, levando em consideração a construção desse conhecimento ao longo da história humana. Utilizamos uma abordagem baseada na História e Filosofia da Ciência (HFC) realizando uma interligação do conteúdo de calor com alguns episódios históricos, tais como os conceitos de Flogístico e Calórico, a determinação do equivalente mecânico do calor, a atribuição do “Joule” como unidade para energia e a importância de Rumford na evolução da teoria do calor, desenvolvendo assim uma prática de ensino que não seja isolada e descontextualizada. Também reproduzimos o famoso experimento de Joule, detalhando sua construção ao utilizar materiais simples e de fácil obtenção. Este recurso didático foi aplicado a uma turma de segundo ano do ensino médio de uma escola pública, e aqui detalharemos as etapas dessa aplicação. Uma pesquisa foi aplicada e intervenções realizadas, onde foram analisadas qualitativamente as superações e desenvolvimento dos conceitos térmicos na potencialidade da aprendizagem significativa e de uma formação integral. Como resultado tivemos um excelente aproveitamento da turma, pois observou-se as transformações nas ideias errôneas dos estudantes à medida que o conceito de calor foi empregado gradativamente ao longo das intervenções.

The use of amantadine in clinical practice still seems limited, despite its increasing evidence in the emergence of vegetative state after traumatic brain injury. We describe the case of an adolescent with severe traumatic brain injury after being run over by a car. After four months of hospitalization in a Central Hospital where he remained in a vegetative state, he was transferred to a Rehabilitation Center. He underwent a comprehensive rehabilitation program with physiotherapy, occupational therapy and speech therapy, including multisensory stimulation and intervention in the surrounding environment. He started amantadine, 50 mg/day, titrated up to 200 mg/day, with significant clinical and functional improvements, and emerged from vegetative state to minimally conscious state at week three and recovered consciousness at the sixth week of amantadine, maintaining progressive improvement, even after drug suspension. The case described underlines the importance of a holistic intervention and corroborates the literature in demonstrating the efficacy and safety of amantadine in the emergence from vegetative state.A utilização da amantadina na prática clínica ainda parece pouco difundida, apesar da evidência crescente na emergência de alterações do estado de consciência após traumatismo cranioencefálico. Descrevemos o caso de um adolescente com traumatismo cranioencefálico grave por atropelamento. Após quatro meses de internamento num hospital central onde se manteve em estado vegetativo foi transferido para um centro de reabilitação. Iniciou um programa de reabilitação integral liderado por equipa médica, incluindo estimulação multissensorial e intervenção no meio envolvente. Iniciou amantadina, 50 mg/dia, titulada até 200 mg/dia, verificando-se melhoria clínica e funcional significativas, com emergência para estado de consciência mínima à terceira semana e recuperação da consciência à sexta semana de amantadina. Manteve melhoria progressiva mesmo após suspensão do fármaco. O caso descrito salienta a importância da intervenção holística e corrobora a literatura ao demonstrar a eficácia e segurança da amantadina na emergência do estado vegetativo.

Resenha do livro de Diego Reis O governo da emergência: Estado de Exceção, guerra ao terror e colonialidade. Rio de Janeiro: Multifoco, 2020

Made available in DSpace on 2022-05-01T15:46:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-01 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Agroforestry systems integrating tree and forage growth are important for maintaining soil health but may change the soil’s physical-hydric properties. Our goal was to investigate the impact of introducing Eucalyptus trees into a pasture on the soil water content throughout the soil profile. The study was conducted in a 6-year-old agroforestry system where two species of Eucalyptus were introduced into a palisade grass pasture. Soil moisture was sampled at 0.0 (planting row), 2.0, 4.0, and 6.0 m (midpoint between tree rows) from the Eucalyptus tree rows. A monoculture palisade grass pasture was used as a control. The soil water content down to a depth of 50 cm was lowest in the tree row and increased with distance from the trees. In the Eucalyptus row, the soil water content in the 0–50 cm layer was lower than in the monoculture pasture. Agroforestry systems decreased the water content in the superficial layers of the soil in the rainy months; in the dry season, the soil water contents in all layers were similar between the Eucalyptus inter-rows. In most seasons, the agroforest systems reduced the forage production close to the Eucalyptus tree rows, up to 2 m from the trees, likely due to the soil water content decrease. Overall, this study showed that in tropical regions with sandy soils, the grass and trees’ competition must be considered when establishing integrated agroforestry systems in order to maximize the advantages and benefits of the diversified agroecosystem. Department of Agronomy Kansas State University Advanced Research Center of Rubber Tree and Agroforestry Systems Agronomic Institute/IAC, SP Department of Energy Engineering in Agriculture State University of Western Paraná, PR Soil and Water Sciences Department University of Florida Department of Crop Science São Paulo State University UNESP, Rua José Barbosa de Barros, 1780, SP Department of Crop Science São Paulo State University UNESP, Rua José Barbosa de Barros, 1780, SP FAPESP: 2013/08664-5 FAPESP: 2014/10656-3 FAPESP: 2016/ 14323-4

Nucleic acid vaccines have become a revolutionary technology to give a fast, safe, cost-effective and efficient response against viral infections, such as SARS-CoV-2 or Human papillomavirus (HPV). However, to ensure their effectiveness, the development of adequate methods to protect, carry, and deliver nucleic acids is fundamental. In this work, nanoparticles (NPs) of chitosan (CS)-tripolyphosphate (TPP)-plasmid DNA (pDNA) were thoroughly modulated and characterized, by measuring the charge and size through dynamic light scattering (DLS) and morphology by scanning electron microscopy (SEM). Stability, cytotoxicity and cellular uptake of NPs were also evaluated. Finally, the effect of polyplexes on the expression of HPV E7 antigen in human fibroblast and RAW cells was investigated through polymerase chain reaction (PCR) and real-time PCR. The results showed NPs with a spherical/oval shape, narrow size distribution 20 mV) and good stability after one month of storage at 4 °C in formulation buffer or when incubated in culture medium and trypsin. In vitro studies of NPs cytotoxicity revealed that the elimination of formulation buffers led to an improvement in the rate of cell viability. The E7 antigen transcription was also increased for NPs obtained with high pDNA concentration (60 μg/mL). The analyzed CS-TPP-pDNA polyplexes can offer a promising vehicle for nucleic acid vaccines, not only in the prevention or treatment of viral infections, but also to fight emergent and future pathogens.

This paper aim was, adjust a time series model to the generated electrical energy series through the wind grid for studying trend, seasonality and making predictions. The used historic series consists in the electric energy generated through the wind grid, collected monthly by the Operador Nacional do Sistema Elétrico. The range is between jan/2007 until mar/2021, with 171 observations. The series was divides into two groups, first (jan/2007 to dec/2019) used for modelling process (calibration) and the other one (jan/2020 to mar/2021) for predictions evaluation (validation). For making predictions it was used apr/2021 to dec/2022 period. In the procedures, first was applied a Box-Cox transform on data scale for turn the model into additive. Then, the presence of trend was checked. From the transformed original series with an order 1 difference, FAC and FACP correlograms, were possible purpose some models. The residual not correlated and a lower AIC were the criteria used for the models. From the chose ones, were made prediction for jan/2020 to mar/2021 period, that were compared to the real observations through EQMP. The SARIMA (5,1,2)×(0,0,3)12 model was chosen because of its lowest EQMP. Other observation is related to the next months followed a rising pattern since 2015. The purposed model for forecasting the amount of electric energy generated by the wind grid will help the managers, giving them time for programming the proper energy’s distribution. El objetivo de este trabajo fue ajustar un modelo de series temporales a la serie de energía eléctrica generada a través de la red eólica para estudiar la tendencia, la estacionalidad y realizar predicciones. La serie histórica utilizada consiste en la energía eléctrica generada a través de la red eólica, recogida mensualmente por el Operador Nacional do Sistema Elétrico. El intervalo está comprendido entre enero/2007 y marzo/2021, con 171 observaciones. La serie fue dividida en dos grupos, el primero (ene/2007 a dic/2019) utilizado para el proceso de modelización (calibración) y el otro (ene/2020 a mar/2021) para la evaluación de las predicciones (validación). Para realizar las predicciones se utilizó el periodo de abr/2021 a dic/2022. En los procedimientos, primero se aplicó una transformación Box-Cox en la escala de datos para convertir el modelo en aditivo. Luego, se verificó la presencia de la tendencia. A partir de la serie original transformada con una diferencia de orden 1, los correlogramas FAC y FACP, fueron posibles para algunos modelos. El residuo no correlacionado y un AIC menor fueron los criterios utilizados para los modelos. A partir de los elegidos, se realizaron predicciones para el periodo enero/2020 a marzo/2021, que fueron comparadas con las observaciones reales a través de EQMP. Se eligió el modelo SARIMA (5,1,2)×(0,0,3)12 por su menor EQMP. Otra observación está relacionada con que los próximos meses han seguido un patrón ascendente desde 2015. El modelo propuesto para predecir la cantidad de energía eléctrica generada por la red eólica ayudará a los gestores, dándoles tiempo para programar la distribución adecuada de la energia. O objetivo deste trabalho foi ajustar um modelo de séries temporais à série de energia elétrica gerada pela matriz eólica com a finalidade de estudar a presença de tendência, sazonalidade e realizar previsões. A série histórica utilizada consiste da produção de energia elétrica gerada pela matriz eólica, coletada mensalmente pelo Operador Nacional do Sistema Elétrico. A série está compreendida entre jan/2007 a mar/2021, com 171 observações. A série foi dividida em dois subconjuntos, ao primeiro (jan/2007 a dez/2019) foi designado o processo de modelagem (calibração) e ao segundo (jan/2020 a mar/2021) foi atribuído a avaliação das previsões (validação). O horizonte de previsão contemplou o período de abr/2021 a dez/2022. Realizou-se uma transformação Box-Cox na escala dos dados para tornar o modelo aditivo. Verificou-se a presença da componente de tendência. A partir dos correlogramas da FAC e FACP da série original transformada com uma diferença de ordem 1 foi possível propor alguns modelos. Buscaram-se modelos com resíduos não correlacionados e com menor AIC. Destes, realizaram-se previsões para o período de jan/2020 a mar/21 que foram comparadas com observações reais através do EQMP. O modelo SARIMA (5,1,2)×(0,0,3)12 foi escolhido, pois apresentou o menor EQMP. Observou-se que os meses subsequentes continuam seguindo o padrão crescente que ela vem mantendo desde de 2015. O modelo proposto para prever a quantidade de energia elétrica gerada pela matriz eólica de curto prazo vai permitir que os gestores tenham tempo suficiente para programar a operação de distribuição de energia de forma adequada.

This discussion paper seeks to contribute to the Brazilian urban development debate by analyzing the recent legislation that institutes the Casa Verde Amarela social housing program (CVA). Created in 2020, CVA arose from a provisory executive order (MP 996, of August 25) reformed on January 12, 2021, by federal law 14,118. This CVA analysis seeks to contribute to its operationalization in line with recognized rights and constitutional, legal, and binding principles present in international agreements to which Brazil is a signatory, particularly the 2030 Agenda (Sustainable Development Goals SDG) and the New Urban Agenda (NAU). This analysis focus on public policy management and its implementation, considering the structures of Brazilian urban development, both normative and political-social, and urbanistic. The evaluation carried out focuses on CVA management, seeking legal and operational instruments created even before the "program" formalization, in addition to regulations elaborated after and before. This prospective evaluation is necessary to present the CVA and its possible impacts on urban, public, and private managers.

Structure and porous geometry are dynamic soil parameters that control several soil processes and functions. This study details the differences in the structure of typical Oxisols regarding the clay amount, biological activity, and mineralogy. Combining 2D and 3D image analysis can provide detailed information about the soil structure and porous system. The objectives of this study were: (i) to describe the soil microstructure and degree of microaggregation; (ii) to quantify porosity, soil pore types, and soil pore size distribution using 2D and 3D techniques; and (iii) to better understand the relationship between the porous system and the biological, chemical, mineralogical, and physical properties of the soil. The study considered four Oxisols: Xantic Kandiustox (P1), Rhodic Haplustox (P2), Anionic Acrustox (P3), and Typic Hapludox (P4). The results showed that all Oxisols have some degree of microaggregation. The Rhodic Haplustox (P2) had the most pronounced degree of microaggregation, which reflects the greater biological activity and gibbsite/kaolinite ratio, and lower hematite/(hematite + goethite) ratio compared to the other Oxisols. The pore types found by 2D analysis were complex pores in P1 and P2 and rounded pores in P3 and P4. The 3D analysis showed that P2 and P3 have a more connected porous system compared to the other Oxisols, evidenced by the lower value of the Euler number. The best connectivity values of the porous system were congruent to improved saturated hydraulic conductivity measured in a separate sample set.

Soil erosion is one of the major problems in the agricultural areas in the world, and straw mulching is a conservation practice that may reduce soil runoff. How much straw mulching is necessary to reduce soil runoff? The objectives of this study were to quantify and characterize the runoff under different levels of oat straw mulching, as well as to analyze the cost of soil erosion. An experiment was performed in a site with the soil recently tilled for peach orchard implementation. In the ridges in the row of the peach orchard, plots were placed in order to quantify soil and nutrient losses by surface runoff due to interril erosion on the dates 23 August 2015 and 13 March 2016, considering the treatments were composed of different amounts of oat straw mulching (0, 1, 2, 4 and 8 Mg ha−1). The results showed that the use of oat straw mulching decreased soil runoff, especially the doses ≥2 Mg ha−1, and the cost to replace the available nutrients P, K, Ca and Mg via mineral fertilizer varies from US$ 75.4 (no mulching) to US$ 2.70 per hectare (8 Mg ha−1 oat straw mulching).

A partir da atuação conjunta de seres humanos em prol de objetivos em comum, emergem situações de potência ao aprendizado e, nesse viés, discente e docentes que atuam num mesmo colegiado juntos a um Comitê de Ética em Pesquisa - CEP - constroem pontes que estimulam a multidisciplinaridade e horizontes da ética na pesquisa. Como objetivo: potencializar reflexões a partir da integração multidisciplinar discente e docente a um CEP, considerando vivências e contribuições para formação continuada. A partir desse contexto puderam ser notados duas vertentes aos nortes do estudo, os quais evidenciam-se fragilidades pela alta rotatividade de integrantes e baixo conhecimento por parte da comunidade científica acerca dos reais trabalhos do CEP, quais sejam: educativo; consultivo e deliberativo. Por sua vez, os pontos potenciais quanto a participação se articulam acerca da atinência e formação crítica sob os vieses de pesquisa no que tangem a ética e as compreensões singulares e multidisciplinares sob um foco central. Desse modo, compreende-se que, a partir de uma atuação conjunta, modelos ampliados e formativos se alicerçam e permitem que se comuniquem com as necessidades singulares, multidisciplinares e plurais de cada pesquisa e seres humanos, sensíveis aos olhares dos pareceristas.

The desert rose, Adenium obesum, an apocynacea native to regions of Africa and the Arabian Peninsula is widely cultivated throughout the world for its ornamental and medicinal values. In Brazil there is a growing interest in the ornamental attributes of A. obesum, which leads to the interest of the scientific community in solving problems that may accompany the cultivation of this plant. Some studies on the forms of management, nutrition and irrigation have been carried out, however, studies that aim to understand diseases and pests that affect the desert rose are still scarce. This study aimed to report the first occurrence of mites of the family Tetranychidae causing damage to desert rose cultivated in a greenhouse in the state of Paraíba, Brazil. Sixty specimens of desert rose were monitored between December 2019 and July 2020 in a greenhouse in the biosciences department of the Federal University of Paraíba. All plants had injuries and damage caused by the mite. The main damages were necrosis, deformation of the edges, closing of the leaves along the central vein and yellowing with total dryness and falling of the leaves. Formation of webs over leaves and flowers. It was concluded that the mites of the family Tetranychidae cause damage to desert roses that can damage their commercial value. ABSTRACT: The desert rose, Adenium obesum, an apocynacea native to regions of Africa and the Arabian Peninsula is widely cultivated throughout the world for its ornamental and medicinal values. In Brazil there is a growing interest in the ornamental attributes of A. obesum, which leads to the interest of the scientific community in solving problems that may accompany the cultivation of this plant. Some studies on the forms of management, nutrition and irrigation have been carried out, however, studies that aim to understand diseases and pests that affect the desert rose are still scarce. This study aimed to report the first occurrence of mites of the family Tetranychidae causing damage to desert rose cultivated in a greenhouse in the state of Paraíba, Brazil. Sixty specimens of desert rose were monitored between December 2019 and July 2020 in a greenhouse in the biosciences department of the Federal University of Paraíba. All plants had injuries and damage caused by the mite. The main damages were necrosis, deformation of the edges, closing of the leaves along the central vein and yellowing with total dryness and falling of the leaves. Formation of webs over leaves and flowers. It was concluded that the mites of the family Tetranychidae cause damage to desert roses that can damage their commercial value. KEYWORDS: desert rose, tetranychidae mite, ornamental plant. RESUMO: A rosa do deserto, Adenium obesum, uma apocinácea nativa de regiões da África e da Península Arábica é amplamente cultivada em todo o mundo por seus valores ornamentais e medicinais. No Brasil existe um interesse crescente pelos atributos ornamentais de A. obesum, o que desperta o interesse da comunidade científica em solucionar os problemas que podem acompanhar o cultivo desta planta. Alguns estudos sobre as formas de manejo, nutrição e irrigação têm sido realizados, no entanto, estudos que visam entender as doenças e pragas que afetam a rosa do deserto ainda são escassos. Este trabalho teve como objetivo relatar a primeira ocorrência de ácaros da família Tetranychidae causando danos à roseira-do-deserto cultivada em casa de vegetação no estado da Paraíba, Brasil. Sessenta espécimes de rosa do deserto foram monitorados entre dezembro de 2019 e julho de 2020 em uma estufa do departamento de biociências da Universidade Federal da Paraíba. Todas as plantas tiveram lesões e danos causados ​​pelo ácaro. Os principais danos foram necrose, deformação das bordas, fechamento das folhas ao longo da nervura central e amarelecimento com ressecamento total e queda das folhas. Formação de teias sobre folhas e flores. Concluiu-se que os ácaros da família Tetranychidae causam danos às rosas do deserto que podem prejudicar seu valor comercial. PALAVRAS-CHAVE: rosa do deserto, ácaro tetranychidae, planta ornamental.

A presença de plantas daninhas em culturas agrícolas acarreta prejuízos diretos em termos de produtividade, causando perdas econômicas, o que torna necessário conhecer qualitativamente e quantitativamente as espécies daninhas que competem com culturas de interesses agronômicos. Dessa forma, objetivou-se com este trabalho conhecer a comunidade de plantas daninhas associadas ao cultivo de mamão através do levantamento fitossociológico. O levantamento foi realizado no agreste alagoano, em uma área de cultivo de mamão com idade de dois anos, para isto foi aplicado o método de quadrado inventário, utilizando-se de um quadrado, cujas dimensões foram de 0,5 x 0,5 m. O mesmo foi lançado aleatoriamente em um total de cem amostragens e realizada a coleta do material presente no interior do quadrado para posterior identificação das plantas daninhas a nível de família, gênero e espécie e determinação da matéria seca. As variáveis avaliadas foram: frequência, densidade e dominância absoluta e relativa e o índice de valor de importância para cada espécie identificada. Com o levantamento fitossociológico foi possível determinar 311 indivíduos distribuídos em 14 famílias e 26 espécies, destacando-se a família Poaceae. A espécie que apresentou maior importância foi a Eleusine indica (L.) Gaertn (capim-pé-de-galinha).

0 0 1 108 619 My House 5 1 726 14.0 96 Normal 0 false false false PT-BR JA X-NONE A tematica “Gases”, no contexto do efeito estufa, foi desenvolvida em aulas experimentais de quimica do Ensino Medio, visando a preparacao para o Exame Nacional do Ensino Medio - ENEM. Monitorados por um professor de quimica, alunos do curso de licenciatura em quimica planejaram aulas praticas, que foram ministradas no laboratorio de ciencias da escola estadual com uso de materiais alternativos e industrializados. Oito turmas do 2o ano do ensino medio participaram deste estudo. A estrategia de ensino produziu a articulacao dos conteudos programaticos trabalhados em sala de aula de forma teorica com a pratica, a partir das observacoes e as evidencias dos resultados experimentais obtidos pelos alunos do ensino medio.

800x600 O forno solar foi um projeto desenvolvido pelos bolsistas do Pibid de Quimica do Instituto Federal de Educacao, IFES, junto ao professor supervisor, visando a conscientizar os alunos do Ensino Medio sobre recursos energeticos e responsabilidade social e ambiental de forma que possam, com base no respeito aos recursos naturais, empreender acoes simples do cotidiano de maneira sustentavel, utilizando energia solar, maior fonte de energia para a humanidade. A utilizacao do forno solar coopera com a preservacao da natureza, uma vez que pode ser construido com materiais reciclaveis e utiliza uma fonte de energia renovavel. O forno solar pode ser utilizado em comunidades desprivilegiadas socialmente pelo seu baixo custo. Os testes realizados no verao foram satisfatorios e possibilitaram assar bolos, pizzas e pao de queijo, mas no inverno os resultados pretendidos nao foram satisfatoriamente alcancados devido a pouca incidencia de sol. Normal 0 21 false false false PT-BR X-NONE X-NONE MicrosoftInternetExplorer4

In current times, DNA vaccines are seen as a promising approach to treat and prevent diseases, such as virus infections and cancer. Aiming at the production of a functional and effective plasmid DNA (pDNA) delivery system, four chitosan polymers, differing in the molecular weight, were studied using the design of experiments (DoE) tool. These gene delivery systems were formulated by ionotropic gelation and exploring the chitosan and TPP concentrations as DoE inputs to maximize the nanoparticle positive charge and minimize their size and polydispersity index (PDI) as DoE outputs. The obtained linear and quadratic models were statistically significant (p-value &lt, 0.05) and non-significant lack of fit, with suitable coefficient of determination and the respective optimal points successfully validated. Furthermore, morphology, stability and cytotoxicity assays were performed to evaluate the endurance of these systems over time and their further potential for future in vitro studies. The subsequent optimization process was successful achieved for the delivery systems based on the four chitosan polymers, in which the smallest particle size was obtained for the carrier containing the 5 kDa chitosan (~82 nm), while the nanosystem prepared with the high molecular weight (HMW) chitosan displayed the highest zeta potential (~+26.8 mV). Delivery systems were stable in the formulation buffer after a month and did not exhibit toxicity for the cells. In this sense, DoE revealed to be a powerful tool to explore and tailor the characteristics of chitosan/pDNA nanosystems significantly contributing to unraveling an optimum carrier for advancing the DNA vaccines delivery field.

Animal-based proteins are the most consumed worldwide given their well-balanced nutritional composition. However, the growing demand for animal proteins will not be sustainable due to their low conversion efficiency and high environmental footprint. Specific consumers dietary restrictions and modern trends emphasize the importance of finding alternative sustainable non-animal sources to meet future food (and, in particular, protein) global needs. Algal biomass is considered a relevant alternative, presenting advantages over terrestrial biomass such as higher growth rate, low water consumption, no competition for arable land, carbonneutral emissions, and production of numerous bioactive compounds. This review provides an overview of recent research advances on algae as source of proteins, including production strategies from relevant protein-producing species. Particular emphasis will be given to algae protein current applications and forthcoming challenges of their use. Nutritional and functional aspects of algae biomass or its protein-enriched fractions will be overviewed., This research work was supported by ALGAVALOR - Lisboa-01-0247- FEDER-035234, supported by Operational Programme for Competitiveness and Internationalization (COMPETE2020), Lisbon Portugal Regional Operational Programme (Lisboa 2020) and Algarve Regional Operational Programme (Algarve 2020) under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). This study was also supported by the Portuguese Foundation for Science and Technology (FCT) under the scope of the strategic funding of UIDB/04469/2020 unit and with a Ph.D. scholarship - SFRH/BD/07527/2020 - and BioTecNorte operation (NORTE-01-0145-FEDER 000004) funded by the ERDF under the scope of Norte2020 - Programa Operacional Regional do Norte. Ricardo N. Pereira acknowledge FCT for its Assistant Research program under the scope of Scientific Stimulus Employment with reference CEECIND/02903/2017., info:eu-repo/semantics/publishedVersion

Orientador: Flávio Augusto Picch Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia Civil, Arquitetura e Urbanismo Resumo: O trabalho padronizado (TP) tem sido amplamente utilizado na manufatura. Por meio de sua aplicação, resultados significativos de produtividade e estabilização de processos têm sido alcançados. Na construção, sua aplicação é ainda embrionária, sendo observadas ações parciais, não existindo ainda conhecimento suficiente sobre as melhores práticas que tragam resultados tão significativos quanto os observados na manufatura. O objetivo desta pesquisa é propor um método para aplicação do trabalho padronizado em serviços de construção. A estratégia de pesquisa utilizada foi a Design Science Research (DSR). Para tanto foram realizados três estudos de caso, com o intuito de desenvolver e validar esse método, que partiu de uma base utilizada para a manufatura, adaptando-o a especificidades da construção, tendo na forma final dez etapas e uma tabela que relaciona as etapas aos documentos do trabalho padronizado utilizados, dando assim uma orientação prática que facilita a aplicação do trabalho padronizado a serviços de construção. Os resultados indicam que ao aplicar o método a produtividade dos funcionários dobrou, a satisfação melhorou e houve redução de desperdício no ambiente de trabalho. Como sugestão para trabalhos futuros, indica-se o teste prático deste método em outros serviços de construção, inclusive que utilizem maquinário, e a avaliação de outros aspectos, como: qualidade do serviço, segurança e ergonomia Abstract: Standardized work has been widely used in manufacturing. Through its application, results have been achieved, such as significant productivity and process stabilization. In construction, its application is still incipient, with partial applications, and there is not yet sufficient knowledge on the best ways to apply and to produce results as important as in manufacturing. The objective of this research is to propose a method for standardized work application in construction services. The research strategy used was Design Science Research (DSR). Therefore, we performed three case studies, in order to develop and validate this method. The method started from a base used for manufacturing, adapting it to the specifics of construction, taking into final form ten steps and a table that lists the steps and relates these steps to standardized work documents, thus giving practical guidance that facilitates application standardized work construction services. The results indicate that by applying this method doubled the productivity of employees, employee satisfaction was improved and waste was reduced in the workplace. Suggestion for future studies indicates the practical test of this method in other building services, including the ones that use machinery and evaluation of other aspects, such as quality, safety and ergonomics Mestrado Arquitetura e Construção Mestre em Engenharia Civil

CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior O titânio e suas ligas têm grande destaque devido a suas excelentes propriedades físicas, tais como elevada resistência mecânica para uma menor densidade relativa em relação aos aços, manutenção de sua resistência mecânica em temperaturas elevadas e alta resistência à corrosão. No entanto, o material possui características que o torna de difícil usinabilidade. Assim, o estudo da usinabilidade das ligas de titânio, como a liga Ti-6Al-4V, tem um papel importante na compreensão do desgaste da ferramenta, que é acelerado pelas altas temperaturas atingidas na interface cavaco-ferramenta. Dessa forma, este trabalho tem como objetivo investigar a influência dos parâmetros de corte na temperatura da interface cavaco-ferramenta medida pelo método do termopar ferramenta-peça no torneamento cilíndrico externo da liga Ti-6Al-4V. Também foi desenvolvida uma metodologia para calibração do sistema, um dos grandes problemas para utilização do método. A ferramenta de corte utilizada foi o metal duro da classe K10 sem revestimento em forma de barra, devidamente afiada. A calibração do sistema termopar ferramenta-peça foi realizada utilizando duas metodologias diferentes, ambas considerando todo o sistema experimental de medição da temperatura e as diversas juntas formadas. Os resultados obtidos nos testes de calibração demonstraram um comportamento linear na relação entre temperatura e potencial elétrico ao longo da faixa de temperaturas usadas na calibração e obtidas nos ensaios experimentais. Além disso, a calibração ao utilizar a contra ponta modificada e o pino desenvolvido no presente trabalho, demonstraram resultados semelhantes. Foram realizados testes de torneamento cilíndrico em que os parâmetros de corte (velocidade de corte, avanço e profundidade de corte) e a condição de lubri-refrigeração (seco ou MQL) foram variadas. Os resultados obtidos mostram que os parâmetros de corte influenciam diretamente nas temperaturas e na força de corte. Titanium and its alloys stand out due to their excellent properties, such as high mechanical strength for low relative weight, conservation of their mechanical strength at high temperatures and extraordinary resistance to corrosion. However, the material has characteristics that make it a difficult-to-cut material. Therefore, the study of the machinability for titanium alloys, such as high mechanical strength for a lower relative density in relation to steels, has an important role in understanding the tool wear which is affected by the high chip tool interface temperatures. Thus, this work aims to investigate the influence of the cutting parameters on the chip-tool interface temperature measured by the tool-piece thermocouple method on the external cylindrical turning of the Ti-6Al-4V alloy. The work also aims to develop a methodology for calibrating the system, one of the major problems for using the method. The cutting tool used was the K10 grade carbide in the form of a properly sharpened bar. The calibration of the tool-piece thermocouple system was performed on the experimental apparatus itself, using two different methodology. The results obtained in the calibration tests demonstrated a linear behavior in the relationship between temperature and voltage over the temperature range used in the calibration. In addition, calibration using the modified revolving tailstock centre and the developed pin have shown similar results. Cylindrical turning tests were performed in which the cutting parameters (cutting speed, feed and depth of cut) and the condition of lubrication (dry or MQL) were varied. The results obtained in this work show that the cutting parameters directly influence the temperatures and the cutting force. Dissertação (Mestrado)

The success of oil and gas exploration in carbonate reservoirs demands better strategies. Concerning the step of acid stimulation, the understanding of the nature of the carbonate matrices and their response to the acids can contribute for improvements of this process. We report a study about the reactivity of six different carbonate rocks with aqueous solutions of hydrochloric (HCl) and acetic (HAc) acids. The reactivity of the samples was determined by measuring the mass loss of the carbonate samples during the acid dissolution process. The results demonstrate that the dolomitization of the matrices is the main factor to decrease the kinetic of dissolution. Based on visual inspection, and micro-computed tomography, it was observed that the cylindrical outcrops with low dolomitization present different patterns of morphological dissolution upon HCl or HAc. For HCl, homogenous radial dissolution is observed, producing a smooth surface, while for HAc, the radial structure is practically preserved, but the surface become very rough. Concerning the inner effect of the acids, variations on the pore distributions of the outcrops were investigated by micro-computed tomography and pore distribution were observed during the dissolution cycles with the acids. This is an indication that the reaction occurs homogeneously from the surface, with negligible dissolution of the internal pore walls, since no pressure and flow procedures were employed in this study.

This dissertation is comprised of two essays that apply tools from applied microeconomics and empirical methods to study important issues in agriculture, environment and health economics. The unifying topic of the essays is the use of economic reasoning and careful research design to identify causal relationships using observational data.In the first essay, I investigate the environmental effects due to pesticides for two different genetically modified (GM) seeds: insect resistant (IR) cotton and herbicide tolerant (HT) soybeans. Using an agricultural production model of a profit maximizing competitive farm, I derive predictions that IR trait decreases the amount of insecticides used and HT trait increases the amount of less toxic herbicides. While the environmental impact of pesticides for IR seeds is lower, for the HT seeds the testable predictions are ambiguous: scale and substitution effects can lead to higher or lower environmental impacts. I use a dataset on commercial farms use of pesticides and biotechnology in Brazil to document environmental effects of GM traits. I explore within-farm variation for farmers planting conventional and GM seeds to identify the effect of adoption on the environmental impact of pesticides measured as quantity of active ingredients of chemicals and the Environmental Impact Quotient index. The findings show that the IR trait reduces the environmental impact of insecticides and the HT trait increases environmental impact due to weak substitution among herbicides of different toxicity levels. This is an important result for three reasons. First, it contributes to uncover environmental effects that have been hidden by the qualitative nature of the change mix of herbicides induced by HT trait. Second, environmental policy makers designing policies for biotechnology adoption might consider this new evidence to differentiate among GM traits that produce positive or negative externalities. Finally, the composition of the EIQ index suggests that the environmental impact of pesticides can have multiple dimensions that might involve farmworker health and safety, consumer safety and ecological impacts. Hence, the results on HT soybeans points to additional avenues of work that should be taken to evaluate each of these possible channels since they can also affect other important outcomes such as human capital accumulation.The second essay studies the behavior of mark-up for antihistaminic medicines, used as a treatment for allergy symptoms caused by seasonal high pollen concentration on air, and test whether it's consistent with models of dynamic price competition with fluctuating demand. I draw on the empirical tests of the theory of dynamic price competition which examine the response of observed price-cost margins - retail minus wholesale prices - to expected demand, controlling for current demand. Using a dataset of retail sales, I estimate a reduced form model that captures some of the characteristics of the dynamic price competition with cyclical demand. It consists of a relationship between prices of antihistaminic drugs and measures of pollen concentration on air, taking into account the current level of demand in a given market. Under two basic assumptions - the marginal costs of drugs in each city is the same and level of pollen concentration on air works as a proxy for the expected demand in a given week and prices respond positively to those expectations -, I find evidence that the behavior of the retail margins is consistent with the predictions of models of dynamic price competition under cyclical demand. The essay makes a contribution to understand the dynamics of behavior in oligopolistic markets that might be of interest to academics and practitioners who wants to understand conduct and performance of industrial markets.