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Africa contains the greatest levels of human genetic variation and is the source of the worldwide range expansion of all modern humans. However, relatively little is known about genomic variation in ethnically diverse African populations. Knowledge of genetic structure within Africa has important implications for the design and implementation of disease association studies in Africans and in African Americans, and for reconstructing modern human origins. In addition, studies of genetic adaptation in Africa have important implications for identifying genes that play an important role in human evolution and disease. The African populations included in this study practice diverse subsistence patterns and have diverse diets (e.g. the study includes hunter-gatherers, pastoralists, agriculturalists and agro- pastoralists). The populations studied live in diverse environments with differing pathogen exposure (tropical forest, savannah, coastal, desert, low altitude and high altitude) and, therefore, are likely to have experienced local adaptation. In this talk I will discuss results of analyses of genome-scale microsatellite and SNP genotyping data in a large set of geographically, linguistically and ethnically diverse African populations, as well as locus- specific analyses of genes that play a role in adaptation to diet and infectious disease. Implications for future whole genome sequencing analyses will be discussed.

Phonological awareness, intelligence, vocabulary and socioeconomic status (SES) have been considered important variables in the acquisition of reading. Nevertheless, attention deficit is associated to low reading performance. The purpose of this work was to investigate correlations among phonological awareness, vocabulary, intelligence, focused attention and reading skills in children with low SES exposed to a non-effective teaching environment. This study included 111 children belonging to socioeconomic classes D and E who were enrolled at a state school. Results pointed to a positive correlation among vocabulary, intelligence, phonological awareness and reading scores. There was no significant correlation between attention measures and reading ability. The relations among the variables continued, even in a population with low SES, although bad teaching environment acts as a limiting factor for the students’ development of their reading ability.

In humans, the ability to digest lactose, the sugar in milk, declines after weaning because of decreasing levels of the enzyme lactase-phlorizin hydrolase, encoded by LCT. However, some individuals maintain high enzyme amounts and are able to digest lactose into adulthood (i.e., they have the lactase-persistence [LP] trait). It is thought that selection has played a major role in maintaining this genetically determined phenotypic trait in different human populations that practice pastoralism. To identify variants associated with the LP trait and to study its evolutionary history in Africa, we sequenced MCM6 introns 9 and 13 and ∼2 kb of the LCT promoter region in 819 individuals from 63 African populations and in 154 non-Africans from nine populations. We also genotyped four microsatellites in an ∼198 kb region in a subset of 252 individuals to reconstruct the origin and spread of LP-associated variants in Africa. Additionally, we examined the association between LP and genetic variability at candidate regulatory regions in 513 individuals from eastern Africa. Our analyses confirmed the association between the LP trait and three common variants in intron 13 (C-14010, G-13907, and G-13915). Furthermore, we identified two additional LP-associated SNPs in intron 13 and the promoter region (G-12962 and T-956, respectively). Using neutrality tests based on the allele frequency spectrum and long-range linkage disequilibrium, we detected strong signatures of recent positive selection in eastern African populations and the Fulani from central Africa. In addition, haplotype analysis supported an eastern African origin of the C-14010 LP-associated mutation in southern Africa.

In this work we are interested in the concept of market efficiency and its relationship with the algorithmic complexity theory. We employ a methodology based on the Lempel-Ziv index to analyze the relative efficiency of high-frequency data coming from the Brazilian stock market.

Submitted by Georgio Oliveira (guerreiroajuricaba31@hotmail.com) on 2022-01-26T08:41:03Z No. of bitstreams: 3 Tese Georgio ??talo Ferreira de Oliveira.pdf: 3445245 bytes, checksum: 54581b14ff58db52521be0696d4531ad (MD5) CARTA DE ENCAMINHAMENTO DE ALUNO PARA O AUTODEPOSITO.pdf: 80484 bytes, checksum: 3dab2a3b988d50411cd43c8b7cc04300 (MD5) Ata de Defesa de Tese Oficial.pdf: 275087 bytes, checksum: 81680c390a7d4192825132c3297b1dbb (MD5) Approved for entry into archive by PPGSCA Sociedade e Cultura na Amaz??nia (ppgsca@ufam.edu.br) on 2022-01-26T12:43:36Z (GMT) No. of bitstreams: 3 Tese Georgio ??talo Ferreira de Oliveira.pdf: 3445245 bytes, checksum: 54581b14ff58db52521be0696d4531ad (MD5) CARTA DE ENCAMINHAMENTO DE ALUNO PARA O AUTODEPOSITO.pdf: 80484 bytes, checksum: 3dab2a3b988d50411cd43c8b7cc04300 (MD5) Ata de Defesa de Tese Oficial.pdf: 275087 bytes, checksum: 81680c390a7d4192825132c3297b1dbb (MD5) Rejected by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br), reason: Ficha Catalogr??fica: a) Palavras-chave - Devem come??ar com a primeira letra mai??scula e as demais min??sculas, exceto quando forem siglas ou nomes pr??prios (Ex.: Reconhecimento territorial) b) A Ficha Catalogr??fica deve ser posicionada na parte inferior da folha conforme gerada pelo sistema. on 2022-01-26T18:46:18Z (GMT) Submitted by Georgio Oliveira (guerreiroajuricaba31@hotmail.com) on 2022-02-04T04:47:04Z No. of bitstreams: 4 CARTA DE ENCAMINHAMENTO DE ALUNO PARA O AUTODEPOSITO.pdf: 80484 bytes, checksum: 3dab2a3b988d50411cd43c8b7cc04300 (MD5) Ata de Defesa de Tese Oficial.pdf: 275087 bytes, checksum: 81680c390a7d4192825132c3297b1dbb (MD5) Tese de Georgio ??talo Ferreira de Oliveira 4 de Fevereiro de 2022.pdf: 3562586 bytes, checksum: 9690d4d3c99ed418baca42b21153a693 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Approved for entry into archive by PPGSCA Sociedade e Cultura na Amaz??nia (ppgsca@ufam.edu.br) on 2022-02-04T12:19:41Z (GMT) No. of bitstreams: 4 CARTA DE ENCAMINHAMENTO DE ALUNO PARA O AUTODEPOSITO.pdf: 80484 bytes, checksum: 3dab2a3b988d50411cd43c8b7cc04300 (MD5) Ata de Defesa de Tese Oficial.pdf: 275087 bytes, checksum: 81680c390a7d4192825132c3297b1dbb (MD5) Tese de Georgio ??talo Ferreira de Oliveira 4 de Fevereiro de 2022.pdf: 3562586 bytes, checksum: 9690d4d3c99ed418baca42b21153a693 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Approved for entry into archive by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br) on 2022-02-04T15:56:07Z (GMT) No. of bitstreams: 4 CARTA DE ENCAMINHAMENTO DE ALUNO PARA O AUTODEPOSITO.pdf: 80484 bytes, checksum: 3dab2a3b988d50411cd43c8b7cc04300 (MD5) Ata de Defesa de Tese Oficial.pdf: 275087 bytes, checksum: 81680c390a7d4192825132c3297b1dbb (MD5) Tese de Georgio ??talo Ferreira de Oliveira 4 de Fevereiro de 2022.pdf: 3562586 bytes, checksum: 9690d4d3c99ed418baca42b21153a693 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Made available in DSpace on 2022-02-04T15:56:07Z (GMT). No. of bitstreams: 4 CARTA DE ENCAMINHAMENTO DE ALUNO PARA O AUTODEPOSITO.pdf: 80484 bytes, checksum: 3dab2a3b988d50411cd43c8b7cc04300 (MD5) Ata de Defesa de Tese Oficial.pdf: 275087 bytes, checksum: 81680c390a7d4192825132c3297b1dbb (MD5) Tese de Georgio ??talo Ferreira de Oliveira 4 de Fevereiro de 2022.pdf: 3562586 bytes, checksum: 9690d4d3c99ed418baca42b21153a693 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2021-10-14 FAPEAM - Funda????o de Amparo ?? Pesquisa do Estado do Amazonas The present thesis has as its title "Quilombola Community of Santa Tereza do Matupiri/Am: Conflict, Resistance and Territorial Recognition on the Andir?? River", a community that is located in the Andir?? River region, municipality of Barreirinha, State of Amazonas. The research had the participation of some inhabitants of the community, people with black ancestry, protagonists of their own history, and with a strong backing in the resistance and struggle in favor of the traditional quilombola communities in the region. The study was based on Oral History, in a qualitative approach, having as research resource semi-directed interviews with the collaborators and recording in a field notebook, these techniques were fundamental for the collection, transcripts and description of the moment of the interviews, occasion in which neither the sonorous always translates what the countenance lets through. The basic theoretical sources that theoretically supported this work were Gomes (1997, 2003 and 2018), Sampaio (1997, 2008, 2011, 2014), Almeida (1998, 2006, 2008, 2012, 2017, 2020), Funes (1995, 2003). ), Cavalcante (2011, 2013, 2020, 2021), Pozza Neto (2011), Costa (2014, 2016) Rocha (2018, 2019) Ranciaro (2004, 2016). The results of this research assertively contemplate the objectives addressed in the primeval proposal of this work, and that during the course of the thesis the questions raised found answers in the speeches of the network of collaborators who composed the field research. And the black leaders, after long years of struggles, managed to succeed in their claims for territory and finally having their lands recognized as quilombola communities, specifically the Quilombola Community of Matupiri, which, according to the Palmares Foundation under ordinance n?? 176, of October 24, 2013, registered in the General Registry Book n?? 16, the collective recognition of the Communities of Boa F??, Trindade, S??o Pedro, Ituquara and Matupiri as quilombola communities. The recognition of these quilombola communities located on the Andir?? River is a response to the demands of the Quilombola Federation, and at the same time a territorial and ethnic matrix valorization, which ratifies the existence of a legally constituted people, and whose formalization granted by the state and emphasized here is result of struggles and persistence of the traditional (black) populations of the Andir?? River. In view of the results presented, it is expected that this quilombola territory will receive attention from the public power, from the federal, state and municipal spheres, and in this way the history, identity and memory of the black and quilombola can remain alive in the interior of the Amazon. A presente tese tem como t??tulo ???Comunidade Quilombola de Santa Tereza do Matupiri/AM: Conflito, Resist??ncia e Reconhecimento Territorial no rio Andir?????, comunidade que est?? localizada na regi??o do Rio Andir??, munic??pio de Barreirinha, Estado do Amazonas. A pesquisa contou com a participa????o de alguns habitantes da comunidade, pessoas com ancestralidade negra, protagonistas de sua pr??pria hist??ria, e com forte lastro na resist??ncia e luta em favor das comunidades tradicionais quilombolas da regi??o. O estudo foi fundamentado na Hist??ria Oral, em abordagem qualitativa, tendo como recurso de investiga????o entrevistas semi-dirigidas aos colaboradores e registro em caderno de campo, essas t??cnicas foram fundamentais para a recolha, transcri????es e descri????o do momento das entrevistas, ocasi??o em que nem sempre a sonora traduz o que o semblante deixa transparecer. As fontes te??ricas basilares que fomentaram teoricamente este trabalho foram Gomes (1997, 2003 e 2018), Sampaio (1997, 2008, 2011, 2014), Almeida (1998, 2006, 2008, 2012, 2017, 2020), Funes (1995, 2003), Cavalcante (2011, 2013, 2020, 2021), Pozza Neto (2011), Costa (2014, 2016) Rocha (2018, 2019) Ranciaro (2004, 2016). Os resultados desta pesquisa contemplam de maneira assertiva aos objetivos tratados na proposta primeva deste trabalho, e que no decorrer da tese as indaga????es levantadas encontraram respostas nas falas da rede de colaboradores que compuseram a pesquisa de campo. E as lideran??as negras ap??s longos anos de lutas travadas, conseguiram lograr ??xito em suas reivindica????es por territ??rio e finalmente tendo suas terras reconhecidas como comunidades quilombolas, especificamente a Comunidade Quilombola do Matupiri, que de acordo com a Funda????o Palmares sob a portaria n?? 176, de 24 de outubro de 2013, registrou-se no Livro de Cadastro Geral n?? 16, o reconhecimento coletivo das Comunidades de Boa F??, Trindade, S??o Pedro, Ituquara e Matupiri como comunidades quilombolas. O reconhecimento dessas comunidades quilombolas localizados no Rio Andir?? s??o uma resposta ??s reivindica????es da Federa????o Quilombola, e ao mesmo tempo uma valoriza????o territorial e da matriz ??tnica, que ratifica a exist??ncia de um povo legalmente constitu??do, e cuja formaliza????o outorgada pelo estado e aqui enfatizada ?? resultado de lutas e persist??ncia das popula????es tradicionais (negras) do Rio Andir??. Diante dos resultados apresentados espera-se que esse territ??rio quilombola receba aten????o do poder p??blico, da esfera federal, estadual e municipal, e dessa forma a hist??ria, a identidade e a mem??ria do negro e quilombola possa se manter viva no interior da Amaz??nia. A Tese de Doutorado foi escrita durante o per??odo pand??mico que assola a humanidade. Acrescentamos que a comunidade quilombola pesquisada foi fechada e com isso enfrentamos severas dificuldades na recolha de entrevistas e a realiza????o da etnografia, mas mesmo assim apresentamos um trabalho denso, que foi aprovado por unanimidade, com louvor e indicado para publica????o.

Submitted by Laura Landau (laulandau@gmail.com) on 2020-10-28T14:53:55Z No. of bitstreams: 4 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Disserta????o_Laura_Landau.docx: 377005721 bytes, checksum: 7e76203ef9ad5c30905cbdfa537064c5 (MD5) UFAM - Laura - Dep??sito-Autodep??sito.pdf: 228977 bytes, checksum: 998013dfd69c581249ae78c2b8c51742 (MD5) Ata_Laura_Landau Assinada.pdf: 1038917 bytes, checksum: e0f6f81e95375003de4aea505d09e793 (MD5) Rejected by PPGCASA Ci??ncias do Ambiente e Sustentabilidade na Amaz??nia (ppgcasasecretaria@ufam.edu.br), reason: Disserta????o em Docx, deve ser em PDF on 2020-11-23T20:29:49Z (GMT) Submitted by Laura Landau (laulandau@gmail.com) on 2020-11-24T18:59:23Z No. of bitstreams: 4 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) UFAM - Laura - Dep??sito-Autodep??sito.pdf: 228977 bytes, checksum: 998013dfd69c581249ae78c2b8c51742 (MD5) Ata_Laura_Landau Assinada.pdf: 1038917 bytes, checksum: e0f6f81e95375003de4aea505d09e793 (MD5) Disserta????o_Laura_Landau_FINAL.pdf: 18028522 bytes, checksum: d575a50e5047abf30ba76efde608119e (MD5) Approved for entry into archive by PPGCASA Ci??ncias do Ambiente e Sustentabilidade na Amaz??nia (ppgcasasecretaria@ufam.edu.br) on 2020-11-24T19:16:16Z (GMT) No. of bitstreams: 4 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) UFAM - Laura - Dep??sito-Autodep??sito.pdf: 228977 bytes, checksum: 998013dfd69c581249ae78c2b8c51742 (MD5) Ata_Laura_Landau Assinada.pdf: 1038917 bytes, checksum: e0f6f81e95375003de4aea505d09e793 (MD5) Disserta????o_Laura_Landau_FINAL.pdf: 18028522 bytes, checksum: d575a50e5047abf30ba76efde608119e (MD5) Approved for entry into archive by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br) on 2020-11-25T19:19:56Z (GMT) No. of bitstreams: 4 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) UFAM - Laura - Dep??sito-Autodep??sito.pdf: 228977 bytes, checksum: 998013dfd69c581249ae78c2b8c51742 (MD5) Ata_Laura_Landau Assinada.pdf: 1038917 bytes, checksum: e0f6f81e95375003de4aea505d09e793 (MD5) Disserta????o_Laura_Landau_FINAL.pdf: 18028522 bytes, checksum: d575a50e5047abf30ba76efde608119e (MD5) Made available in DSpace on 2020-11-25T19:19:56Z (GMT). No. of bitstreams: 4 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) UFAM - Laura - Dep??sito-Autodep??sito.pdf: 228977 bytes, checksum: 998013dfd69c581249ae78c2b8c51742 (MD5) Ata_Laura_Landau Assinada.pdf: 1038917 bytes, checksum: e0f6f81e95375003de4aea505d09e793 (MD5) Disserta????o_Laura_Landau_FINAL.pdf: 18028522 bytes, checksum: d575a50e5047abf30ba76efde608119e (MD5) Previous issue date: 2020-06-16 Every social group is connected to an important network structured by nature, human beings and technical objects resulting from the meeting of the first two. Traditional communities are great examples of how it is possible for societies to compose a network that respects culture, identity, local way of life and the natural world. This study focused on delineating the sociotechnical network that supports the production of artisanal objects from the quilombola communities of the Andir?? River, located in the municipality of Barreirinha, Amazonas State. The research took place specifically in three communities: Santa Tereza do Matupiri, Ituquara and S??o Paulo do A??u, in order to understand how their actors connect and act. The quilombola???s identity, territory and way of life shown to be definitive for artisanal making, and from these, the composition house-swidden-forest-river emerges guiding the practices of handicrafts. The objects studied here, broom, paneiro, manioc sifter, tipiti and various clay artifacts, are essential to guarantee family subsistence and result from the relationship of artisans with the group. Quilombolas recognized as feitores (makers) those whose life was organized around the making. They became artisans recognized by their peers based on manual practices, stimulated since childhood, accumulated traditional knowledge, experience in the forests and rivers and engagement with the material. The artisan is a hybrid actor, resulting from the quilombola's deep connection with his community, with nature and with the material manipulated. The objects that are created by them accumulate the history of the one who does it, of those who taught him, of the ethno-ecological relationship with the surrounding nature, the community, and the needs of its members. Todo grupo social est?? conectado ?? uma importante rede estruturada pela natureza, seres humanos e objetos t??cnicos resultantes do encontro dos dois primeiros. Comunidades tradicionais s??o grandes exemplos de como ?? poss??vel para as sociedades comporem uma rede que respeita a cultura, identidade, modo de vida local e mundo natural. Este estudo teve como foco delinear a rede sociot??cnica que sustenta a produ????o de objetos artesanais de comunidades quilombolas do Rio Andir??, localizadas no mun??cipio de Barreirinha, Amazonas. A pesquisa aconteceu especificamente em tr??s comunidades: Santa Tereza do Matupiri, Ituquara e S??o Paulo do A??u, a fim de entender como seus atores se conectam e atuam. A identidade, territ??rio e modo de vida dos quilombolas se mostraram definitivos para o fazer artesanal, e a partir destes o conjunto casa-ro??a-mata-rio surge guiando as pr??ticas do artesanato. Os objetos aqui estudados, vassoura, paneiro, peneira, tipiti e diversos artefatos de barro, s??o imprescind??veis para a garantia da subsist??ncia familiar e resultam da rela????o dos artes??os com o conjunto. Os quilombolas reconhecidos como feitores, s??o aqueles cuja vida se organizou em volta do fazer. Se tornaram artes??os reconhecidos por seus pares a partir das pr??ticas manuais desde crian??as estimuladas, dos saberes tradicionais acumulados, da experi??ncia na mata e rios e do engajamento com o material. O artes??o se mostra um ator h??brido que ?? resultado da conex??o profunda do quilombola com sua comunidade, com a natureza e com o material trabalhado. Os objetos que s??o criados por estes evidenciam a hist??ria daquele que faz, daqueles que o ensinaram, da rela????o etnoecol??gica com a natureza a volta, da comunidade e necessidades de seus membros. Tive que submeter duas vezes pois a parte que devemos colocar a carta e a ata n??o ficou clara. Sugest??o ?? que no ??ltimo bot??o para finalizar a submiss??o apare??a algo como "finalizar processo, deseja continuar?"

Submitted by Joana Silva (joana.borges.freitas@gmail.com) on 2019-07-11T01:42:16Z No. of bitstreams: 3 Disserta????o Final- TEDE UFAM.pdf: 3630763 bytes, checksum: 8d6232e501ee562bcd33a910f8048861 (MD5) Ata defesa.pdf: 922212 bytes, checksum: 99736cba3c939dc7cb72a462ba58d95d (MD5) Encaminhamento disserta????o.pdf: 637486 bytes, checksum: 317f47d9c696e125bb794ae7c50e7a26 (MD5) Approved for entry into archive by PPGCASA Programa de Ci??ncias do Ambiente e Sustentabilidade na Amaz??nia (ppgcasasecretaria@ufam.edu.br) on 2019-07-11T20:03:15Z (GMT) No. of bitstreams: 3 Disserta????o Final- TEDE UFAM.pdf: 3630763 bytes, checksum: 8d6232e501ee562bcd33a910f8048861 (MD5) Ata defesa.pdf: 922212 bytes, checksum: 99736cba3c939dc7cb72a462ba58d95d (MD5) Encaminhamento disserta????o.pdf: 637486 bytes, checksum: 317f47d9c696e125bb794ae7c50e7a26 (MD5) Approved for entry into archive by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br) on 2019-07-15T14:12:10Z (GMT) No. of bitstreams: 3 Disserta????o Final- TEDE UFAM.pdf: 3630763 bytes, checksum: 8d6232e501ee562bcd33a910f8048861 (MD5) Ata defesa.pdf: 922212 bytes, checksum: 99736cba3c939dc7cb72a462ba58d95d (MD5) Encaminhamento disserta????o.pdf: 637486 bytes, checksum: 317f47d9c696e125bb794ae7c50e7a26 (MD5) Made available in DSpace on 2019-07-15T14:12:10Z (GMT). No. of bitstreams: 3 Disserta????o Final- TEDE UFAM.pdf: 3630763 bytes, checksum: 8d6232e501ee562bcd33a910f8048861 (MD5) Ata defesa.pdf: 922212 bytes, checksum: 99736cba3c939dc7cb72a462ba58d95d (MD5) Encaminhamento disserta????o.pdf: 637486 bytes, checksum: 317f47d9c696e125bb794ae7c50e7a26 (MD5) Previous issue date: 2019-05-31 CNPq - Conselho Nacional de Desenvolvimento Cient??fico e Tecnol??gico FAPEAM - Funda????o de Amparo ?? Pesquisa do Estado do Amazonas 05592981126995 This research deals with health production in a traditional Amazonian community and its relationship with the environment, whose main objective was to analyze the living health networks produced in the community of Santa Tereza do Matupiri, located in the river Andir??, in the municipality of Barreirinha, in the region of Baixo Amazon river. It is a remnant community of quilombos recognized in 2013 from the organizational movement to claim and materialize their territorial rights. The community is home to the Quilombola River Andir??, initially composed of five communities. The method used was the cartographic approach, methodological path that allows the construction of the knowledge from the researcher's involvement and mixture with the field. In this way, it was possible to know the processes that conform the quilombola way of life of the river Andir??, allowing connections with the living networks, as well as the understanding of the notion of territoriality, social identity and health care practices, both by traditional methods and services available in the public health system Esta pesquisa versa sobre a produ????o de sa??de numa comunidade tradicional da Amaz??nia e sua rela????o com o ambiente, cujo objetivo central foi analisar as redes vivas de sa??de produzidas na comunidade Santa Tereza do Matupiri, localizada no rio Andir??, Munic??pio de Barreirinha, regi??o do Baixo Rio Amazonas. Trata- se de uma comunidade remanescente de quilombos reconhecida no ano 2013 a partir do movimento organizativo para reivindica????o e materializa????o de seus direitos territoriais, a referida comunidade ?? sede do territ??rio quilombola rio Andir??, composto inicialmente por cinco comunidades. O m??todo utilizado foi a abordagem cartogr??fica, caminho metodol??gico que permite a constru????o do conhecimento a partir do envolvimento e mistura do pesquisador com o campo. Desse modo, foi poss??vel conhecer os processos que conformam os modos de vida quilombola do rio Andir??, permitindo conex??es com as redes vivas, bem como a compreens??o da no????o de territorialidade, identidade social e pr??ticas de cuidado em sa??de, tanto por m??todos tradicionais, quanto pelos servi??os dispon??veis no sistema p??blico de sa??de.

Submitted by Bruce Osborne (bru__osborne@hotmail.com) on 2019-08-21T00:52:43Z No. of bitstreams: 4 Tese_Bruce_Vers??o Final_Texto Limpo.pdf: 1709930 bytes, checksum: f7e9eeb2520839d0f7b62b5cc4ba78c5 (MD5) ATA-1.pdf: 591117 bytes, checksum: c98a05013f18acd68393536e4c965697 (MD5) ATA-2.pdf: 162227 bytes, checksum: 1787d32d757c2ae7087e4987d7236e38 (MD5) encaminhamento-Yoshiko.pdf: 216811 bytes, checksum: aa482a1cbcaec9ce8f3a2ec68bc49ac8 (MD5) Rejected by PPGSCA Sociedade e Cultura na Amaz??nia (secppgsca@gmail.com), reason: Carta de encaminhamento sem data, vers??o final incorreta (n??o deve constar a ata) e a ata deve ser anexada em documento ??nico. on 2019-08-21T13:15:59Z (GMT) Submitted by Bruce Osborne (bru__osborne@hotmail.com) on 2019-08-23T15:20:46Z No. of bitstreams: 4 Tese_Bruce_??ltima Vers??o_Texto Limpo.pdf: 1191989 bytes, checksum: 84bb12a660b4743c8ff7416e95452b93 (MD5) Ata_final.pdf: 590887 bytes, checksum: 8c25bb39f35c6f7c2a3a3b24501494fa (MD5) encaminhamento-Yoshiko.pdf: 327486 bytes, checksum: 774a997b43c0374731966a35c2124bd7 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Approved for entry into archive by PPGSCA Sociedade e Cultura na Amaz??nia (secppgsca@gmail.com) on 2019-08-23T15:25:41Z (GMT) No. of bitstreams: 4 Tese_Bruce_??ltima Vers??o_Texto Limpo.pdf: 1191989 bytes, checksum: 84bb12a660b4743c8ff7416e95452b93 (MD5) Ata_final.pdf: 590887 bytes, checksum: 8c25bb39f35c6f7c2a3a3b24501494fa (MD5) encaminhamento-Yoshiko.pdf: 327486 bytes, checksum: 774a997b43c0374731966a35c2124bd7 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Approved for entry into archive by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br) on 2019-08-26T14:30:46Z (GMT) No. of bitstreams: 4 Tese_Bruce_??ltima Vers??o_Texto Limpo.pdf: 1191989 bytes, checksum: 84bb12a660b4743c8ff7416e95452b93 (MD5) Ata_final.pdf: 590887 bytes, checksum: 8c25bb39f35c6f7c2a3a3b24501494fa (MD5) encaminhamento-Yoshiko.pdf: 327486 bytes, checksum: 774a997b43c0374731966a35c2124bd7 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Made available in DSpace on 2019-08-26T14:30:46Z (GMT). No. of bitstreams: 4 Tese_Bruce_??ltima Vers??o_Texto Limpo.pdf: 1191989 bytes, checksum: 84bb12a660b4743c8ff7416e95452b93 (MD5) Ata_final.pdf: 590887 bytes, checksum: 8c25bb39f35c6f7c2a3a3b24501494fa (MD5) encaminhamento-Yoshiko.pdf: 327486 bytes, checksum: 774a997b43c0374731966a35c2124bd7 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2019-05-14 92988081234 This study analyses the work of substitute university professors and their position within the Federal University of Amazonas as an institution and their temporary relation to tenured professors, with a view to deciding whether the work of substitute professors may be deemed precarious or not. After discussing the literature on the precarious nature of much of today???s employment, and presenting the copious legislation, both national and local, governing the contracting of substitute professors by federal universities, it becomes clear that sucessive federal governments have shaped a mould for substitute professors which restricts their work conditions to the point that the function of substitute professor cannot but be seen as presenting a wide range of precarious characteristics. These characteristics serve a dual purpose: first, they are internally restrictive, imposing multiple limitations on the substitute???s activities, and indicating absolute precariousness; secondly they are external, insulating the substitute???s work area in such a way as to make it impossible for the existence of a temporary position to justify the hiring of another career professor. This interpretation is enriched by the questionnaire answered by 88 of the current 224 substitute professors, which confirms two crucial, though seemingly contradictory points: first, the substitute professor???s work cannot be seen as anything but precarious and secondly, the overwhelming majority have a positive evaluation of their experience as substitute professors. However, even though substitute professors make up 20% of UFAM faculty, the university does not possess any kind of process that governs the routine and the academic posititon of substitute professors, a lacuna which ends up affecting the substitute???s remaining relationships. Academic relations within the university, both professor-student and tenured professor-probationary professor are based essentially on ethics. The temporary and limited character of the substitute professor???s work, it seems, does not demand the ethical concerns that underlie the remaining academic relations within the university, resulting in the quality and quantity overloads apparent from the majority of the answers to the questionnaire. Este estudo analisa o trabalho do professor substituto e sua rela????o com a institui????o Universidade Federal do Amazonas e com o professor de carreira, enquanto colegas tempor??rios, com o objetivo de decidir se o trabalho do professor substituto pode ser considerado prec??rio ou n??o. Depois de discutir a literatura sobre a natureza prec??ria de muitos dos trabalhos atuais e apresentar a farta legisla????o, federal e local, sobre a contrata????o de professores substitutos por universidades federais, conclui-se que a forma de professor substituto constru??da por sucessivos governos restringe as condi????es de trabalho do magist??rio superior, de tal forma que a fun????o de professor substituto s?? possa ser vista como uma pl??iade de caracter??sticas de precariedade. Essas caracter??sticas t??m finalidade dupla: a primeira ?? restritiva internamente, vez que imp??e m??ltiplas limita????es ao desempenho da fun????o e indica um n??vel de precariedade absoluta; a segunda ?? externa e tem o objetivo de blindar o campo de trabalho do professor substituto de tal forma que seja imposs??vel usar a exist??ncia da vaga tempor??ria para justificar a contrata????o de professor efetivo. Contribui para essa interpreta????o um question??rio respondido por 88 dos 224 atuais professores substitutos, que confirma duas quest??es cruciais, embora aparentemente contradit??rias: primeiro, o trabalho do professor substituto na Universidade Federal do Amazonas re??ne, de fato, todas as condi????es de precariedade, e, segundo, a vasta maioria tem uma avalia????o positiva de sua experi??ncia como professor substituto. No entanto, apesar de constituir 20% do corpo docente da UFAM, inexiste na universidade qualquer tipo de processo que governe a rotina e as rela????es acad??micas do professor substituto, uma lacuna que acaba afetando as demais rela????es do substituto. As rela????es acad??micas existentes na universidade, tanto professor-aluno como professor de carreira-professor em est??gio probat??rio t??m como substrato essencial a ??tica. O car??ter tempor??rio e limitado do trabalho do professor substituto, ao que parece, n??o imp??e os cuidados ??ticos que subjazem ??s demais rela????es acad??micas existentes na universidade, resultando na sobrecarga qualitativa e quantitativa verificada na maioria das respostas ao question??rio. Que o processo de preenchimento seja modelado no preenchimento do IR: pode-se ir fazendo, deixando claros para posterior preenchimento. Atrasei desnecessariamente por estar esperando o CPF da minha orientadora N??o.

Submitted by Jo??o marinho da Rocha (jmrocha.hist@hotmail.com) on 2019-07-08T13:39:13Z No. of bitstreams: 5 carta de encaminhamento.joao marinho da rocha.pdf: 354374 bytes, checksum: f743f3adfec2d81bb9de07e3ac005d33 (MD5) DAS SEMENTES AOS TRONCOS. hist??ria e mem??ria do movimento quilombola do Andir??. Jo??o Marinho da Rocha.pdf: 3572944 bytes, checksum: ab9bf3b5d65ab000a06ba0e1ec7f776d (MD5) ata defesa Jo????o marinho da rocha.pdf: 1083844 bytes, checksum: 4546dc139bb78a77b489fd471a19351c (MD5) ficha catalogr??fica.pdf: 1851 bytes, checksum: 56ef23d909c16c6642ec91d3d1939422 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Approved for entry into archive by PPGSCA Sociedade e Cultura na Amaz??nia (secppgsca@gmail.com) on 2019-07-08T14:03:12Z (GMT) No. of bitstreams: 5 carta de encaminhamento.joao marinho da rocha.pdf: 354374 bytes, checksum: f743f3adfec2d81bb9de07e3ac005d33 (MD5) DAS SEMENTES AOS TRONCOS. hist??ria e mem??ria do movimento quilombola do Andir??. Jo??o Marinho da Rocha.pdf: 3572944 bytes, checksum: ab9bf3b5d65ab000a06ba0e1ec7f776d (MD5) ata defesa Jo????o marinho da rocha.pdf: 1083844 bytes, checksum: 4546dc139bb78a77b489fd471a19351c (MD5) ficha catalogr??fica.pdf: 1851 bytes, checksum: 56ef23d909c16c6642ec91d3d1939422 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Approved for entry into archive by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br) on 2019-07-09T20:34:25Z (GMT) No. of bitstreams: 5 carta de encaminhamento.joao marinho da rocha.pdf: 354374 bytes, checksum: f743f3adfec2d81bb9de07e3ac005d33 (MD5) DAS SEMENTES AOS TRONCOS. hist??ria e mem??ria do movimento quilombola do Andir??. Jo??o Marinho da Rocha.pdf: 3572944 bytes, checksum: ab9bf3b5d65ab000a06ba0e1ec7f776d (MD5) ata defesa Jo????o marinho da rocha.pdf: 1083844 bytes, checksum: 4546dc139bb78a77b489fd471a19351c (MD5) ficha catalogr??fica.pdf: 1851 bytes, checksum: 56ef23d909c16c6642ec91d3d1939422 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Made available in DSpace on 2019-07-09T20:34:25Z (GMT). No. of bitstreams: 5 carta de encaminhamento.joao marinho da rocha.pdf: 354374 bytes, checksum: f743f3adfec2d81bb9de07e3ac005d33 (MD5) DAS SEMENTES AOS TRONCOS. hist??ria e mem??ria do movimento quilombola do Andir??. Jo??o Marinho da Rocha.pdf: 3572944 bytes, checksum: ab9bf3b5d65ab000a06ba0e1ec7f776d (MD5) ata defesa Jo????o marinho da rocha.pdf: 1083844 bytes, checksum: 4546dc139bb78a77b489fd471a19351c (MD5) ficha catalogr??fica.pdf: 1851 bytes, checksum: 56ef23d909c16c6642ec91d3d1939422 (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2019-04-26 FAPEAM - Funda????o de Amparo ?? Pesquisa do Estado do Amazonas 92 9925634 03 From 2005, the Quilombola social movement of the Ansay, based on an identity project initiated a production of memory about itself, connecting to the "scenarios of rights" proposed constitutionally from 1988, and in 2013 achieves recognition as " Quilombos of the River Ansay ". The communities studied are Santa Tereza do Matupiri, Boa F??, Ituquara, S??o Pedro, Trindade and their respective nuclei of Pagoa, S??o Paulo do A????, Lily of the Valley and St. Mark. We situate our narrative in the field of social history of post-abolition and in the interdisciplinary dialogues between history and social sciences, from methodological perspectives such as oral and microhistory history. The thesis assumes the purpose of analyzing the relationship between the processes of the construction of the ethnic identity and the Quilombola territorialities in Antell. For this, it identifies the mechanisms and forms of knowledge created, mobilized and that mark the trajectories of five communities in the process of constructing the new ethnic identity and Quilombola territoriality. It verifies how this construction of ethnic identity indicates paths to the processes of specific territorialities quilombolas. It evidences how these processes of building ethnic identity and territorialities are appropriated by the social groups of communities. The lexicon, the dialogue between the disciplinary fields, the meeting of the normative (legal) and the political and the processes of legitimation of the Quilombola social movement and memory by recognition, are present in the universe of this thesis. A partir de 2005 o movimento social quilombola do Andir??, pautado num projeto de identidade iniciou uma produ????o de mem??ria sobre si, conectando-se aos ???cen??rios de direitos??? propostos constitucionalmente a partir de 1988, e em 2013 consegue reconhecimento como ???quilombos do rio Andir?????. As comunidades estudadas s??o Santa Tereza do Matupiri, Boa F??, Ituquara, S??o Pedro, Trindade e os seus respectivos n??cleos de Pagoa, S??o Paulo do A????, L??rio do Vale e S??o Marcos. Situamos nossa narrativa no campo da hist??ria social do p??s-aboli????o e nos di??logos interdisciplinares entre hist??ria e ci??ncias sociais, a partir de perspectivas metodol??gicas como hist??ria oral e micro-hist??ria. A pesente tese assume o prop??sito de analisar a rela????o entre os processos de constru????o da identidade ??tnica e as territorialidades quilombolas no Andir??. Para isso identifica os mecanismos e as formas de conhecimentos criados, mobilizados e que marcam as trajet??rias de cinco comunidades no processo de constru????o da nova identidade ??tnica e territorialidade quilombola. Verifica como essa constru????o da identidade ??tnica indica caminhos para os processos de territorialidades espec??ficas quilombolas. Evidencia como esses processos de constru????o da identidade ??tnica e das territorialidades s??o apropriados pelos grupos sociais das comunidades. O l??xico, o di??logo entre os campos disciplinares, o encontro do normativo (legal) e do pol??tico e os processos de legitima????o do movimento social quilombola e da mem??ria pelo reconhecimento, est??o presentes no universo desta tese.

Assistive technologies have been proposed for the locomotion of people with spinal cord injury (SCI). One of them is the neuroprosthesis that arouses the interest of developers and health professionals bearing in mind the beneficial effects promoted in people with SCI. Thus, the first session of this chapter presents the principles of human motility and the impact that spinal cord injury causes on a person’s mobility. The second session presents functional electrical stimulation as a solution for the immobility of paralyzed muscles. It explains the working principles of constituent modules and main stimulatory parameters. The third session introduces the concepts and characteristics of neural prosthesis hybridization. The last two sessions present and discuss examples of hybrid neuroprostheses. Such systems employ hybrid assistive lower limb strategies to evoke functional movements in people with SCI, associating the motor effects of active and/or passive orthoses to a functional electrical stimulation (FES) system. Examples of typical applications of FES in rehabilitation are discussed.

Submitted by LUCIA LIRA (lucialira1@gmail.com) on 2018-12-11T00:09:19Z No. of bitstreams: 4 TESE FINAL.pdf: 71178125 bytes, checksum: 8963634da4e389e05e16eec1e3356aab (MD5) ATA 01.jpg: 655710 bytes, checksum: 28338ea9a2350633d0f4873aae488df5 (MD5) ATA 02.jpg: 459553 bytes, checksum: 75371a7b26a8b3569c1dc7e465b9c151 (MD5) CARTA DE ENCAMINHAMENTO.jpg: 370760 bytes, checksum: 8067569fc1053b49eb8d59469c2e0e61 (MD5) Approved for entry into archive by PPGSCA Sociedade e Cultura na Amaz??nia (secppgsca@gmail.com) on 2018-12-19T14:28:12Z (GMT) No. of bitstreams: 4 TESE FINAL.pdf: 71178125 bytes, checksum: 8963634da4e389e05e16eec1e3356aab (MD5) ATA 01.jpg: 655710 bytes, checksum: 28338ea9a2350633d0f4873aae488df5 (MD5) ATA 02.jpg: 459553 bytes, checksum: 75371a7b26a8b3569c1dc7e465b9c151 (MD5) CARTA DE ENCAMINHAMENTO.jpg: 370760 bytes, checksum: 8067569fc1053b49eb8d59469c2e0e61 (MD5) Approved for entry into archive by Divis??o de Documenta????o/BC Biblioteca Central (ddbc@ufam.edu.br) on 2018-12-19T15:36:46Z (GMT) No. of bitstreams: 4 TESE FINAL.pdf: 71178125 bytes, checksum: 8963634da4e389e05e16eec1e3356aab (MD5) ATA 01.jpg: 655710 bytes, checksum: 28338ea9a2350633d0f4873aae488df5 (MD5) ATA 02.jpg: 459553 bytes, checksum: 75371a7b26a8b3569c1dc7e465b9c151 (MD5) CARTA DE ENCAMINHAMENTO.jpg: 370760 bytes, checksum: 8067569fc1053b49eb8d59469c2e0e61 (MD5) Made available in DSpace on 2018-12-19T15:36:46Z (GMT). No. of bitstreams: 4 TESE FINAL.pdf: 71178125 bytes, checksum: 8963634da4e389e05e16eec1e3356aab (MD5) ATA 01.jpg: 655710 bytes, checksum: 28338ea9a2350633d0f4873aae488df5 (MD5) ATA 02.jpg: 459553 bytes, checksum: 75371a7b26a8b3569c1dc7e465b9c151 (MD5) CARTA DE ENCAMINHAMENTO.jpg: 370760 bytes, checksum: 8067569fc1053b49eb8d59469c2e0e61 (MD5) Previous issue date: 2018-08-27 92 999642229 How is a celebration of a Catholic saint the main element of a community's ethnic identity? This was one of the research questions of this dissertation carried out at Barranco???s Community, in Pra??a 14 de Janeiro, in the urban center of Manaus. This community had as its ascendants, black Maranhenses who arrived in the late nineteenth century and for more than a hundred years have been building their ethnic identity according to their own ancestral African culture. They have been faithful to Saint Benedict since 1890. In 2014, the community defined itself as quilombolas, symbol of struggle, perseverance and resistance. Faced with such reality, the research aimed to analyze the process at the identity construction of this Community, identified through the trajectory of religious faith, interpreted here from the point of view of ethnography about the symbolic representations that perpass the celebrations in honor to Saint Benedict. Recognition of this local population as "Quilombo Urbano" by the Funda????o Cultural Palmares was a great achievement that has been transforming life of this black Community, which has called for public policies since the 1988 Constitution. In 2015, the party was awarded as Cultural and Intangible Heritage State of Amazonas, ratifying the dimension of recognition as a guiding concept of this work. The methodological course of this study was supported by participant research, direct observation, interviews, audio and video recordings. The fieldwork sought strategies of ethnography and cross - referencing with a bibliographic reference in the interdisciplinary area of History, Geography and Social Sciences. The last part of the study is the analysis of the voices of the community that ratify faith and religious tradition, sociocultural (festive mainly) manifestations, coming from their ancestors. ??C??mo una fiesta de un santo cat??lico es el elemento principal de la identidad ??tnica de una comunidad? Esta fue una de las cuestiones de investigaci??n de esta Tesis realizada en la Comunidad del Barranco, en el Barrio Plaza 14 de Janeiro, centro urbano de Manaus. Esta comunidad tuvo como ascendientes negros maranhenses (naturales del Estado brasile??o de Maranh??o), que llegaron al lugar a finales del siglo XIX y por m??s de cien a??os vienen construyendo su identidad ??tnica en consonancia con la propia cultura ancestral africana. Ellos tienen en la religiosidad, la devoci??n a San Benito desde 1890. En 2014, la comunidad se autodefini?? como quilombolas, s??mbolo de lucha, perseverancia y resistencia. Ante esta realidad, la investigaci??n objetiv?? analizar el proceso de construcci??n identitaria de esa Comunidad, identificado a partir de la trayectoria de fe religiosa, aqu?? interpretada desde el punto de vista de la etnograf??a acerca de las representaciones simb??licas que atraviesan las fiestas en homenaje a San Benito. El reconocimiento como "Quilombo Urbano" por la Fundaci??n Cultural Palmares fue una gran conquista que viene transformando la vida de esa comunidad negra, que clama por pol??ticas p??blicas basadas en los diversos Decretos Ley, desde la Constituci??n de 1988. En 2015, la fiesta fue agraciada como Patrimonio Cultural e Inmaterial del a??o del Estado de Amazonas, ratificando la dimensi??n del reconocimiento como concepto orientador de este trabajo. La base metodol??gica tuvo el apoyo de la investigaci??n participante, observaci??n directa, entrevistas, grabaciones en audio y video. El trabajo de campo busc?? estrategias de la etnograf??a y entrecruzamiento con referencial bibliogr??fico en el ??rea interdisciplinaria de la Historia, Geograf??a y Ciencias Sociales. Se finaliza el trabajo con el an??lisis de las voces de los comunitarios que ratifican la fe, la tradici??n religiosa y las manifestaciones socioculturales (festivas principalmente), provenientes de sus antepasados. Como uma festa de um santo cat??lico ?? o elemento principal da identidade ??tnica de uma comunidade? Esta foi uma das quest??es de investiga????o desta Tese junto ?? Comunidade do Barranco, no Bairro Pra??a 14 de Janeiro, centro urbano de Manaus. Esta comunidade teve, como ascendentes, negros maranhenses que chegaram ao local no final do s??culo XIX e, por mais de cem anos, v??m construindo sua identidade ??tnica em conson??ncia com a pr??pria cultura ancestral africana. Eles t??m, na religiosidade, a devo????o a S??o Benedito desde 1890. Em 2014, a Comunidade se autodefiniu como quilombola, s??mbolo de luta, perseveran??a e resist??ncia. Diante de tal realidade, a pesquisa objetivou analisar o processo de constru????o identit??ria dessa comunidade, identificado a partir da trajet??ria de f?? religiosa, aqui interpretada sob o ponto de vista da etnografia acerca das representa????es simb??licas que perpassam as festas em homenagem a S??o Benedito. O reconhecimento como ???Quilombo Urbano???, pela Funda????o Cultural Palmares foi uma grande conquista que vem transformando a vida dessa comunidade negra que clama por pol??ticas p??blicas baseadas nos diversos Decretos-Lei, desde a Constitui????o de 1988. Em 2015, a festa foi agraciada como Patrim??nio Cultural e Imaterial do estado do Amazonas, ratificando a dimens??o do reconhecimento como conceito norteador deste trabalho. O percurso metodol??gico teve o apoio da pesquisa participante, observa????o direta, entrevistas, grava????es em ??udio e v??deo. O trabalho de campo buscou estrat??gias da etnografia e entrecruzamento com referencial bibliogr??fico na ??rea interdisciplinar da Hist??ria, Geografia e Ci??ncias Sociais. Finaliza-se o trabalho com a an??lise das vozes dos comunit??rios que ratificam a f?? e a tradi????o religiosa, as manifesta????es socioculturais (festivas principalmente), advindas dos seus ancestrais. A dificuldade encontrada foi n??o ter informa????es do que seria pedido durante o preenchimento, como nome dos membros da banca com url, cpf; inclus??o do resumo e palavras chave nas diversas l??nguas que o autor colocou no seu trabalho, o que atrapalha na hora do preenchimento, se n??o temos essas informa????es em m??os. Sim, esta Tese analisou como se deu a constru????o identit??ria de uma fam??lia de descendentes de maranhenses, filhos de ex-escravos que chegaram ao Bairro da Pra??a 14 de Janeiro, em 1890 e deram continuidade ??s tradi????es culturais de matriz africana, de religiosidade cat??lica at?? a presente data. Devido a hist??ria de lutas e resist??ncias foram certificados pela Funda????o Cultural Palmares, em 2014, como quilombolas. A trajet??ria, mem??rias e narrativas est??o descritas neste trabalho cient??fico.

We investigated global patterns of genetic variation and signatures of natural selection at host genes relevant to SARS-CoV-2 infection ( ACE2 , TMPRSS2 , DPP4 , and LY6E ). We analyzed novel data from 2,012 ethnically diverse Africans and 15,997 individuals of European and African ancestry with electronic health records, and integrated with global data from the 1000GP. At ACE2 , we identified 41 non-synonymous variants that were rare in most populations, several of which impact protein function. However, three non-synonymous variants were common among Central African hunter-gatherers from Cameroon and are on haplotypes that exhibit signatures of positive selection. We identify strong signatures of selection impacting variation at regulatory regions influencing ACE2 expression in multiple African populations. At TMPRSS2 , we identified 13 amino acid changes that are adaptive and specific to the human lineage. Genetic variants that are targets of natural selection are associated with clinical phenotypes common in patients with COVID-19., Competing Interests: Declaration of Interests No conflict of interest

Following publication of the original article [1], a typographical error in the formula for calculating d i in the "Scans for local adaptation" subsection in the Method section, was identified. The correct formula should be.