3,366 results on '"R. Stuart"'
Search Results
202. Deep Geological CO2 Storage: Principles Reviewed, and Prospecting for Bio-energy Disposal Sites
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Haszeldine, R. Stuart
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- 2006
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203. Investigation and management of a large community mumps outbreak among young adults in Toronto, Canada, January 2017–February 2018
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R Stuart, V Dubey, O Ozaldin, J Maclachlan, L Bromley, L Shulman, and A Summers
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Outbreak Report ,Mumps outbreak ,business.industry ,Psychological intervention ,Outbreak ,General Medicine ,Vaccination ,Mumps vaccine ,Cohort ,Medicine ,Social media ,Young adult ,business ,Demography - Abstract
BACKGROUND: In 2017, a mumps outbreak was identified in a cohort of 18–34 year olds in Toronto, Canada. OBJECTIVE: To describe a large community mumps outbreak in an urban centre from January 2017 to February 2018 among young adults. METHODS: A broad range of interventions were implemented in an attempt to reach the target audience; including case and contact management, vaccination clinics at schools and clinicians’ offices, school exclusions, bar inspections, traditional communication strategies (including health care provider updates and posters) and newer communication strategies (including three sequential social media campaigns). RESULTS: A total of 143 cases of mumps were identified. Although cases’ ages ranged from three to 72 years, most (76%) were 18–34 year olds, many of whom had frequented bars and local food establishments in downtown Toronto. 84% (n=120) of the cases were community-acquired. Only 16% (n=23) of the cases reported exposures in schools and post-secondary school institutions. Of those, 39% (n=56) of cases had an unknown vaccination history; 34% (n=49) were either not vaccinated or partially vaccinated with one dose of measles-mumps-rubella vaccine; and 27% (n=38) had received the recommended two doses of mumps vaccine. Determining vaccination status was a challenge, in part due to the lack of a registry. Vaccination was recommended when subjects were known to have had fewer than two doses of vaccine or had an unknown vaccination status. A social media campaign, emphasizing the risk of social activities if not protected from the mumps, yielded over 500,000 impressions from Facebook and Twitter messages and ads and an impressive engagement rate of between 1% and 10x%. CONCLUSION: This was the largest mumps outbreak in Toronto in over 20 years. Among young adults, ongoing social media and traditional communication campaigns can contribute to the control of community mumps outbreaks. Encouraging vaccine uptake is desirable, but without a vaccine registry it is difficult to assess vaccination coverage among adults. Susceptible cohorts of young adults who were not adequately vaccinated pose a risk for future outbreaks. Given that almost 30% of the mumps cases were fully vaccinated with two doses of mumps-containing vaccine, even two doses may not provide complete protection.
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- 2018
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204. Étude et gestion d’une importante éclosion communautaire d’oreillons parmi les jeunes adultes de Toronto, Canada, de janvier 2017 à février 2018
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V Dubey, L Bromley, J Maclachlan, A Summers, L Shulman, O Ozaldin, and R Stuart
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General Medicine - Published
- 2018
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205. 'A More Powerful Effect upon the Body': Early Mormonism's Theory of Racial Redemption and American Religious Theories of Race
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Joseph R. Stuart
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Cultural Studies ,060303 religions & theology ,History ,060101 anthropology ,Endowment ,media_common.quotation_subject ,Religious studies ,Doctrine ,06 humanities and the arts ,0603 philosophy, ethics and religion ,Lineage (anthropology) ,Power (social and political) ,Race (biology) ,Protestantism ,Wife ,0601 history and archaeology ,Liturgy ,Sociology ,media_common - Abstract
This paper examines Joseph Smith's construction of a racialized theology, which drew upon conceptions of Abrahamic lineage and the possibility of “racial redemption” for peoples of African descent through conversion to Mormonism. This ran against the grain of his Protestant and Catholic contemporaries’ religious understandings of race. He expanded upon earlier iterations of his ideas with the introduction of new rituals and liturgy related to LDS temples. Smith's wife may have invited a person of African descent to participate in this new liturgy before his murder in June 1844. The views he expressed about peoples of African descent before his death are inchoate, although high-ranking Mormons related to Smith seemed to have agreed with the possibility of racial redemption. After Smith's death, Brigham Young and other Mormon leaders framed the LDS temple and priesthood restriction in terms of Smith's liturgy rather than any of Smith's varied teachings on race. This paper also argues that Mormonism's racial restriction arose from its roots in the sealing ritual rather than ecclesiological power structures. Mormonism's racial doctrine has often been described as a “priesthood ban,” referring to ecclesiastical authority. However, this discounts the religious contexts in which it arose and excludes the experiences of women and children, who were not allowed to participate in the endowment or sealing ordinances. This paper places Mormonism's temple liturgy at the front and center of the LDS Church's priesthood and temple restriction.
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- 2018
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206. Observation of Complement Protein Gene Expression Before and After Surgery in Opioid-Consuming and Opioid-Naive Patients
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Daniel W. Odell, Alan R. Light, Kathleen C. Light, Ken B. Johnson, Ami R. Stuart, and Jacob Radtke
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Male ,Gene Expression ,Inflammation ,Pharmacology ,03 medical and health sciences ,Complement inhibitor ,0302 clinical medicine ,030202 anesthesiology ,Complement Factor D ,Gene expression ,medicine ,Humans ,Pain, Postoperative ,business.industry ,Complement C4b-Binding Protein ,Binding protein ,Complement System Proteins ,Complement system ,Complement (complexity) ,Analgesics, Opioid ,Anesthesiology and Pain Medicine ,Opioid ,Elective Surgical Procedures ,Female ,medicine.symptom ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Opioids may influence inflammation. We compared genes associated with pain and inflammation in patients who consumed opioids (3-120 mg of oral morphine equivalents per day) with those who did not for differential expression. White blood cells were assayed in 20 patients presenting for total lower extremity joint replacement. We focused on messenger ribonucleic acid expression of complement proteins. We report that the expression of a complement inhibitor, complement 4 binding protein A, was reduced, and the expression of a complement activator, complement factor D, was increased in opioid-consuming patients. We conclude that opioid consumption may influence expression of complement activators and inhibitors.
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- 2018
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207. Determination of In-Situ Reservoir Absolute Permeability Under Multiphase-Flow Conditions Using Transient Well Testing
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Z. Zakariya, Yan Pan, Medhat M. Kamal, Matthew R. Stuart, Fnu Suleen, Erin Mire, Aysegul Dastan, and Samiha Morsy
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In situ ,Multiphase flow ,Energy Engineering and Power Technology ,Geology ,02 engineering and technology ,Mechanics ,010502 geochemistry & geophysics ,01 natural sciences ,Fuel Technology ,Reservoir monitoring ,020401 chemical engineering ,Transient (oscillation) ,0204 chemical engineering ,Relative permeability ,0105 earth and related environmental sciences - Abstract
Summary A new method is presented that uses transient well testing to determine the in-situ absolute permeability of the formation when three phases of fluids are flowing simultaneously in the reservoir. The method was verified through simulation using synthetic data, and its applicability and practicality were confirmed through application to field data. Determining the absolute permeability over the reservoir scale using readily available transient testing data will have major benefits in accelerating history matching and improving reservoir-performance prediction. A recently developed method (Kamal and Pan 2010) to determine the in-situ absolute permeability under conditions of two-phase flow extended the applicability of transient well testing and has been adopted in commercial software. In this study, We extend the analysis method to determine the absolute permeability and fluid saturations when three phases are flowing in the reservoir. We show that an optimization procedure is needed to obtain the required results in this case. We show that the theoretical bases for the method presented to determine absolute permeability from transient tests under multiphase-flow conditions are the same as those used in obtaining relative permeability relations from core analysis and predicting reservoir performance in reservoir-simulation studies. The method presented in this study uses surface flow rates and the fluid properties of the three phases. It also uses the same relative permeability relations used in the simulation models, thus ensuring that the same permeability values calculated from field data are used in history matching and predicting the performance of the reservoir. It is assumed that the fluid saturations are relatively uniform in the region around the well at the time of the transient test. The method was verified by comparing the input values with the results obtained from analyzing several synthetic tests that were produced by numerical simulation. Data from a deepwater field were also used to test the practicality and validity of the method. For the field case, the method was verified by matching reservoir production and pressure using the calculated absolute permeability. Excellent agreements were obtained for both synthetic and field cases.
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- 2018
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208. Imide arylation with aryl(TMP)iodonium tosylates
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Souradeep Basu, David R. Stuart, and Alexander H. Sandtorv
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Steric effects ,metal-free ,Letter ,diaryliodonium ,010402 general chemistry ,01 natural sciences ,Medicinal chemistry ,Coupling reaction ,lcsh:QD241-441 ,chemistry.chemical_compound ,lcsh:Organic chemistry ,Moiety ,arylation ,Imide ,Potassium phthalimide ,lcsh:Science ,Phthalimides ,hypercoordinate iodine ,010405 organic chemistry ,Ligand ,Aryl ,Organic Chemistry ,0104 chemical sciences ,Chemistry ,chemistry ,C–N coupling ,lcsh:Q - Abstract
Herein, we describe the synthesis of N-aryl phthalimides by metal-free coupling of potassium phthalimide with unsymmetrical aryl(TMP)iodonium tosylate salts. The aryl transfer from the iodonium moiety occurs under electronic control with the electron-rich trimethoxyphenyl group acting as a competent dummy ligand. The yields of N-aryl phthalimides are moderate to high and the coupling reaction is compatible with electron-deficient and sterically encumbered aryl groups.
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- 2018
209. MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
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Matthew S. Block, Robert A. Vierkant, Peter F. Rambau, Stacey J. Winham, Philipp Wagner, Nadia Traficante, Aleksandra Tołoczko, Daniel G. Tiezzi, Florin Andrei Taran, Peter Sinn, Weiva Sieh, Raghwa Sharma, Joseph H. Rothstein, Teresa Ramón y Cajal, Luis Paz-Ares, Oleg Oszurek, Sandra Orsulic, Roberta B. Ness, Gregg Nelson, Francesmary Modugno, Janusz Menkiszak, Valerie McGuire, Bryan M. McCauley, Marie Mack, Jan Lubiński, Teri A. Longacre, Zheng Li, Jenny Lester, Catherine J. Kennedy, Kimberly R. Kalli, Audrey Y. Jung, Sharon E. Johnatty, Mercedes Jimenez-Linan, Allan Jensen, Maria P. Intermaggio, Jillian Hung, Esther Herpel, Brenda Y. Hernandez, Andreas D. Hartkopf, Paul R. Harnett, Prafull Ghatage, José M. García-Bueno, Bo Gao, Sian Fereday, Ursula Eilber, Robert P. Edwards, Christiani B. de Sousa, Jurandyr M. de Andrade, Anita Chudecka-Głaz, Georgia Chenevix-Trench, Alicia Cazorla, Sara Y. Brucker, Jennifer Alsop, Alice S. Whittemore, Helen Steed, Annette Staebler, Kirsten B. Moysich, Usha Menon, Jennifer M. Koziak, Stefan Kommoss, Susanne K. Kjaer, Linda E. Kelemen, Beth Y. Karlan, David G. Huntsman, Estrid Høgdall, Jacek Gronwald, Marc T. Goodman, Blake Gilks, María José García, Peter A. Fasching, Anna de Fazio, Suha Deen, Jenny Chang-Claude, Francisco J. Candido dos Reis, Ian G. Campbell, James D. Brenton, David D. Bowtell, Javier Benítez, Paul D.P. Pharoah, Martin Köbel, Susan J. Ramus, Ellen L. Goode, D. Bowtell, G. Chenevix-Trench, A. Green, P. Webb, A. DeFazio, D. Gertig, N. Traficante, S. Fereday, S. Moore, J. Hung, K. Harrap, T. Sadkowsky, N. Pandeya, M. Malt, A. Mellon, R. Robertson, T. Vanden Bergh, M. Jones, P. Mackenzie, J. Maidens, K. Nattress, Y.E. Chiew, A. Stenlake, H. Sullivan, B. Alexander, P. Ashover, S. Brown, T. Corrish, L. Green, L. Jackman, K. Ferguson, K. Martin, A. Martyn, B. Ranieri, J. White, V. Jayde, P. Mamers, L. Bowes, L. Galletta, D. Giles, J. Hendley, K. Alsop, T. Schmidt, H. Shirley, C. Ball, C. Young, S. Viduka, Hoa Tran, Sanela Bilic, Lydia Glavinas, Julia Brooks, R. Stuart-Harris, F. Kirsten, J. Rutovitz, P. Clingan, A. Glasgow, A. Proietto, S. Braye, G. Otton, J. Shannon, T. Bonaventura, J. Stewart, S. Begbie, M. Friedlander, D. Bell, S. Baron-Hay, A. Ferrier, G. Gard, D. Nevell, N. Pavlakis, S. Valmadre, B. Young, C. Camaris, R. Crouch, L. Edwards, N. Hacker, D. Marsden, G. Robertson, P. Beale, J. Beith, J. Carter, C. Dalrymple, R. Houghton, P. Russell, M. Links, J. Grygiel, J. Hill, A. Brand, K. Byth, R. Jaworski, P. Harnett, R. Sharma, G. Wain, B. Ward, D. Papadimos, A. Crandon, M. Cummings, K. Horwood, A. Obermair, L. Perrin, D. Wyld, J. Nicklin, M. Davy, M.K. Oehler, C. Hall, T. Dodd, T. Healy, K. Pittman, D. Henderson, J. Miller, J. Pierdes, P. Blomfield, D. Challis, R. McIntosh, A. Parker, B. Brown, R. Rome, D. Allen, P. Grant, S. Hyde, R. Laurie, M. Robbie, D. Healy, T. Jobling, T. Manolitsas, J. McNealage, P. Rogers, B. Susil, E. Sumithran, I. Simpson, K. Phillips, D. Rischin, S. Fox, D. Johnson, S. Lade, M. Loughrey, N. O'Callaghan, W. Murray, P. Waring, V. Billson, J. Pyman, D. Neesham, M. Quinn, C. Underhill, R. Bell, L.F. Ng, R. Blum, V. Ganju, I. Hammond, Y. Leung, A. McCartney, M. Buck, I. Haviv, D. Purdie, D. Whiteman, and N. Zeps
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Carcinoma, Ovarian Epithelial/metabolism ,Adult ,0301 basic medicine ,Oncology ,medicine.medical_specialty ,Myeloid Differentiation Factor 88/metabolism ,Carcinoma, Ovarian Epithelial ,Article ,03 medical and health sciences ,Ovarian tumor ,0302 clinical medicine ,Internal medicine ,Immunohistochemistry/methods ,Biomarkers, Tumor ,medicine ,Carcinoma ,Humans ,Clear-cell ovarian carcinoma ,Tissue Array Analysis/methods ,Survival analysis ,Aged ,Ovarian Neoplasms ,Tissue microarray ,business.industry ,Hazard ratio ,General Medicine ,Middle Aged ,Ovarian Neoplasms/metabolism ,medicine.disease ,ANÁLISE DE SOBREVIVÊNCIA ,Immunohistochemistry ,Survival Analysis ,3. Good health ,Toll-Like Receptor 4 ,Serous fluid ,Toll-Like Receptor 4/metabolism ,030104 developmental biology ,Tissue Array Analysis ,Biomarkers, Tumor/metabolism ,030220 oncology & carcinogenesis ,Myeloid Differentiation Factor 88 ,Female ,business ,Ovarian cancer - Abstract
Objective: To evaluate myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 (TLR4) expression in relation to clinical features of epithelial ovarian cancer, histologic subtypes, and overall survival. Patients and Methods: We conducted centralized immunohistochemical staining, semi-quantitative scoring, and survival analysis in 5263 patients participating in the Ovarian Tumor Tissue Analysis consortium. Patients were diagnosed between January 1, 1978, and December 31, 2014, including 2865 high-grade serous ovarian carcinomas (HGSOCs), with more than 12,000 person-years of follow-up time. Tissue microarrays were stained for MyD88 and TLR4, and staining intensity was classified using a 2-tiered system for each marker (weak vs strong). Results: Expression of MyD88 and TLR4 was similar in all histotypes except clear cell ovarian cancer, which showed reduced expression compared with other histotypes (P
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- 2018
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210. Offshore Geological Storage of Hydrogen: Is This Our Best Option to Achieve Net-Zero?
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Hassanpouryouzband, Aliakbar, primary, Joonaki, Edris, additional, Edlmann, Katriona, additional, and Haszeldine, R. Stuart, additional
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- 2021
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211. The effect of COVID-19 public health restrictions on the health of people with musculoskeletal conditions and symptoms: the CONTAIN study
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Macfarlane, Gary J, primary, Hollick, Rosemary J, additional, Morton, LaKrista, additional, Heddle, Maureen, additional, Bachmair, Eva-Maria, additional, Anderson, R Stuart, additional, Whibley, Daniel, additional, Keenan, Karen Forrest, additional, Murchie, Peter, additional, Stelfox, Kevin, additional, Beasley, Marcus J, additional, and Jones, Gareth T, additional
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- 2021
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212. A comparative study of odorants for gas escape detection of natural gas and hydrogen
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Mouli-Castillo, Julien, primary, Orr, Georgina, additional, Thomas, James, additional, Hardy, Nikhil, additional, Crowther, Mark, additional, Haszeldine, R. Stuart, additional, Wheeldon, Mark, additional, and McIntosh, Angus, additional
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- 2021
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213. Thorny Problems in Data (-Intensive) Science: Data scientists face challenges spanning academic and non-academic institutions.
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Borgman, Christine L., Pasquetto, Irene V., Geiger, R. Stuart, Boscoe, Bernadette M., Darch, Peter T., Cabasse-Mazel, Charlotte, Thompson, Cheryl, and Golshan, Milena S.
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DATA science ,INFORMATION scientists ,RESEARCH ,DATA scrubbing ,VOCATIONAL guidance ,RESEARCH funding - Abstract
The authors discuss the issue of data scientists and their role in scientific research. They mention the growth in the use of big data and the work involved in cleaning that data, the need for data scientists to understand the terminology and subject matter in the discipline in which they are working, and the problems of future careers and funding for projects.
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- 2020
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214. Insecticide Use and the Ecology of Invasive Liriomyza Leafminer Management
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R., Stuart, primary, Gao, Yulin, additional, and Lei, Zhongren, additional
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- 2013
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215. Amazing Stories Volume 120
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A. R. Stuart and A. R. Stuart
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- Adventure stories, American
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Amazing Stories Volume 120 is a great collection of action short stories from'The Golden Age of Science Fiction'. Featured here are six short stories by different authors:'Beer-Trust Busters', by A. R. Stuart,'Raiders of the Second Moon'by Gene Ellermant,'Space-Trap At Banya Tor'by W. J. Matthews,'The Bloodhounds of Zirth'by Lloyd Palmer,'Spacemen Are Borny'by Bolling Branham, and'Planet in Reverse'by Henry Guth.
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- 2022
216. Management Strategies for Western Flower Thrips and the Role of Insecticides
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R., Stuart, primary and Funderburk, Joe, additional
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- 2012
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217. Evolving Computational Dynamical Systems to Recognise Abnormal Human Motor Function
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Lones, Michael A., primary, Smith, Stephen L., additional, Tyrrell, Andy M., additional, Alty, Jane E., additional, and Jamieson, D. R. Stuart, additional
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- 2012
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218. 'Writing up rather than writing down': becoming Wikipedia literate.
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Heather Ford and R. Stuart Geiger
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- 2012
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219. What aren't we measuring?: methods for quantifying wiki-work.
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Aaron Halfaker, Brian Keegan, Andrea Forte, R. Stuart Geiger, Dario Taraborelli, Maryana Pinchuk, and Mikhil Masli
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- 2012
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220. Changing the tutorial experience in introductory economics
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Alexander, W Robert J and McDougall, R Stuart
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Business ,Business, international ,Economics ,Regional focus/area studies - Abstract
It had been apparent to teaching staff of our department for some time that the tutorial system in place for large introductory-level classes was not functioning optimally. Tutorials were re-designed around problem solving and applications of theory, undertaken by students in small groups. Assessment was also re-designed in keeping with the changed course emphasis. In evaluating the success or otherwise of this change in approach, we used both qualitative and quantitative techniques. The qualitative responses of both students and tutors were very positive. Quantitative evidence of improved outcomes is harder to adduce, but we did find sufficient evidence to encourage colleagues to extend the changes to other large classes., Changing the tutorial experience in introductory economics 1. Introduction Becker and Watts (2001) have observed, from their extensive longitudinal survey on teaching methods in undergraduate economics courses, that the most [...]
- Published
- 2003
221. Approach to the management of end-stage renal disease
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Rodger, R Stuart C
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- 2012
222. A quantitative assessment of the hydrogen storage capacity of the UK continental shelf
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Scafidi, Jonathan, primary, Wilkinson, Mark, additional, Gilfillan, Stuart M.V., additional, Heinemann, Niklas, additional, and Haszeldine, R. Stuart, additional
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- 2021
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223. “Garbage in, garbage out” revisited: What do machine learning application papers report about human-labeled training data?
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Geiger, R. Stuart, primary, Cope, Dominique, additional, Ip, Jamie, additional, Lotosh, Marsha, additional, Shah, Aayush, additional, Weng, Jenny, additional, and Tang, Rebekah, additional
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- 2021
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224. ORES
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Halfaker, Aaron, primary and Geiger, R. Stuart, additional
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- 2020
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225. Comparative evaluation of battery electric and hydrogen fuel cell electric vehicles for zero carbon emissions road vehicle fuel in Scotland
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Low, John, primary, Haszeldine, R. Stuart, additional, and Mouli-Castillo, Julien, additional
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- 2020
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226. Thorny problems in data (-intensive) science
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Scroggins, Michael J., primary, Pasquetto, Irene V., additional, Geiger, R. Stuart, additional, Boscoe, Bernadette M., additional, Darch, Peter T., additional, Cabasse-Mazel, Charlotte, additional, Thompson, Cheryl, additional, Golshan, Milena S., additional, and Borgman, Christine L., additional
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- 2020
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227. Racial Formation and Re-formation in Twentieth-Century Civil Rights Movements
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Joseph R. Stuart
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Cultural Studies ,History ,Political science ,Political economy ,Civil rights movements ,Racial formation theory - Published
- 2018
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228. Self-radiolysis of tritiated water. 4. The scavenging effect of azide ions (N3−) on the molecular hydrogen yield in the radiolysis of water by 60Co γ-rays and tritium β-particles at room temperature
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Jintana Meesungnoen, Jean-Paul Jay-Gerin, Sunuchakan Sanguanmith, Craig R. Stuart, and Patrick Causey
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Materials science ,Hydrogen ,Tritiated water ,General Chemical Engineering ,chemistry.chemical_element ,Linear energy transfer ,02 engineering and technology ,General Chemistry ,Electron ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Photochemistry ,01 natural sciences ,7. Clean energy ,0104 chemical sciences ,Ion ,chemistry.chemical_compound ,chemistry ,13. Climate action ,Yield (chemistry) ,Radiolysis ,Tritium ,0210 nano-technology - Abstract
The effect of the azide ion N3− on the yield of molecular hydrogen in water irradiated with 60Co γ-rays (∼1 MeV Compton electrons) and tritium β-electrons (mean electron energy of ∼7.8 keV) at 25 °C is investigated using Monte Carlo track chemistry simulations in conjunction with available experimental data. N3− is shown to interfere with the formation of H2 through its high reactivity towards hydrogen atoms and, but to a lesser extent, hydrated electrons, the two major radiolytic precursors of the H2 yield in the diffusing radiation tracks. Chemical changes are observed in the H2 scavengeability depending on the particular type of radiation considered. These changes can readily be explained on the basis of differences in the initial spatial distribution of primary radiolytic species (i.e., the structure of the electron tracks). In the “short-track” geometry of the higher “linear energy transfer” (LET) tritium β-electrons (mean LET ∼5.9 eV nm−1), radicals are formed locally in much higher initial concentration than in the isolated “spurs” of the energetic Compton electrons (LET ∼0.3 eV nm−1) generated by the cobalt-60 γ-rays. As a result, the short-track geometry favors radical–radical reactions involving hydrated electrons and hydrogen atoms, leading to a clear increase in the yield of H2 for tritium β-electrons compared to 60Co γ-rays. These changes in the scavengeability of H2 in passing from tritium β-radiolysis to γ-radiolysis are in good agreement with experimental data, lending strong support to the picture of tritium β-radiolysis mainly driven by the chemical action of short tracks of high local LET. At high N3− concentrations (>1 M), our H2 yield results for 60Co γ-radiolysis are also consistent with previous Monte Carlo simulations that suggested the necessity of including the capture of the precursors to the hydrated electrons (i.e., the short-lived “dry” electrons prior to hydration) by N3−. These processes tend to reduce significantly the yields of H2, as is observed experimentally. However, this dry electron scavenging at high azide concentrations is not seen in the higher-LET 3H β-radiolysis, leading us to conclude that the increased amount of intra-track chemistry intervening at early time under these conditions favors the recombination of these electrons with their parent water cations at the expense of their scavenging by N3−.
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- 2018
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229. A criteria-driven approach to the CO2 storage site selection of East Mey for the acorn project in the North Sea
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Clare E. Bond, Eric James Mackay, R. Stuart Haszeldine, Juan Alcalde, Alan James, Daniel R. Faulkner, Niklas Heinemann, Saeed Ghanbari, Richard H. Worden, M. J. Allen, European Commission, Ministerio de Ciencia, Innovación y Universidades (España), Alcalde, Juan, and Alcalde, Juan [0000-0001-9806-5600]
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Site selection ,Process (engineering) ,020209 energy ,Stratigraphy ,Acorn project ,East Mey ,02 engineering and technology ,010501 environmental sciences ,Oceanography ,01 natural sciences ,Backup ,CO2 storage ,0202 electrical engineering, electronic engineering, information engineering ,TOPSIS ,0105 earth and related environmental sciences ,business.industry ,Environmental resource management ,Carbon capture and storage (timeline) ,Geology ,CCS ,Geophysics ,Workflow ,Work (electrical) ,13. Climate action ,Scalability ,Economic Geology ,North Sea ,business - Abstract
Carbon Capture and Storage (CCS) is an essential tool in the fight against climate change. Any prospective storage site must meet various criteria that ensure the effectiveness, safety and economic viability of the storage operations. Finding the most suitable site for the storage of the captured CO2 is an essential part of the CCS chain of activity. This work addresses the site selection of a second site for the Acorn CCS project, a project designed to develop a scalable, full-chain CCS project in the North Sea (offshore northeast Scotland). This secondary site has been designed to serve as a backup and upscaling option for the Acorn Site, and has to satisfy pivotal project requirements such as low cost and high storage potential. The methodology followed included the filtering of 113 input sites from the UK CO2Stored database, according to general and project-specific criteria in a multi-staged approach. This criteria-driven workflow allowed for an early filtering out of the less suitable sites, followed by a more comprehensive comparison and ranking of the 15 most suitable sites. A due diligence assessment was conducted of the top six shortlisted sites to produce detailed assessment of their storage properties and suitability, including new geological interpretation and capacity calculations for each site. With the new knowledge generated during this process, a critical comparison of the sites led to selection of East Mey as the most suitable site, due to its outstanding storage characteristics and long-lasting hydrocarbon-production history, that ensure excellent data availability to risk-assess storage structures. A workshop session was held to present methods and results to independent stakeholders; feedback informed the final selection criteria. This paper provides an example of a criteria-driven approach to site selection that can be applied elsewhere., Project ACT-Acorn is gratefully thanked for funding this study. ACT Acorn, project 271500, received funding from BEIS (UK), RCN (Norway) and RVO (Netherland), and was co-funded by the European Commission under the ERA-Net instrument of the Horizon 2020 programme. ACT Grant number 691712. J. Alcalde is funded by MICINN (Juan de la Cierva fellowship - IJC2018-036074-I). S. Ghanbari is currently supported by the Energi Simulation. Energi Simulation is also thanked for funding the chair in reactive transport simulation held by E. Mackay.
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- 2021
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230. Aryl Transfer Selectivity in Metal-Free Reactions of Unsymmetrical Diaryliodonium Salts
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David R. Stuart
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010405 organic chemistry ,Chemistry ,Aryl ,Radical ,Organic Chemistry ,Reactive intermediate ,General Chemistry ,Reaction intermediate ,010402 general chemistry ,01 natural sciences ,Aryne ,Catalysis ,0104 chemical sciences ,chemistry.chemical_compound ,Reagent ,Organic chemistry ,Chemoselectivity - Abstract
Aromatic rings are found in a wide variety of products, including pharmaceuticals, agrochemicals, and functional materials. Diaryliodonium salts are new reagents used to transfer aryl groups under both metal-free and metal-catalyzed reactions and thereby synthesize arene-containing compounds. This minireview focuses on recent studies in selective aryl transfer reactions from unsymmetrical diaryliodonium salts under metal-free conditions. Reactions reported from 2007 to 2017, which represents a period of significant growth in diaryliodonium salt chemistry, are presented and organized by the type of reactive intermediate formed in the reaction. Specifically, reactions involving λ3 -iodane, λ3 -iodane radical anions, aryl radicals, and arynes are discussed. Chemoselectivity trends in aryl transfer are compared and contrasted across reaction intermediates and translation to potential auxiliaries are posited.
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- 2017
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231. An Admix Approach To Determine Counter Anion Effects on Metal-Free Arylation Reactions with Diaryliodonium Salts
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Thomas L. Seidl and David R. Stuart
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Anions ,Azides ,Molecular Structure ,010405 organic chemistry ,Chemistry ,Diphenyliodonium tosylate ,Biphenyl Compounds ,Organic Chemistry ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Ion ,Tosyl Compounds ,chemistry.chemical_compound ,Onium Compounds ,Nucleophile ,Metal free ,Organic chemistry ,Molecule ,Salts ,Screening tool ,Azide - Abstract
A method to determine the effect of counter anions in metal-free arylation reactions of diaryliodonium salts is described. This approach avoids the independent synthesis of individual diaryliodonium salts and potentially enables assessment of a large number of different counter anions, including those that are synthetically challenging to install. Diaryliodonium tosylate salts serve as a general precursor for this approach, and an azide arylation reaction was used to develop this strategy. Further optimization and representative scope of azide arylation is demonstrated in yields that range from 74-95% (89% average). The use of this method as a screening tool has also been validated with arylation reactions of three different nucleophiles employing diphenyliodonium tosylate.
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- 2017
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232. Using Acceptance and Commitment Therapy to Improve Outcomes in Functional Movement Disorders: A Case Study
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Christopher D. Graham, Simon R. Stuart, Daniel J. O’Hara, and Steven Kemp
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050103 clinical psychology ,medicine.medical_specialty ,Mindfulness ,Neurology ,Psychotherapist ,medicine.medical_treatment ,05 social sciences ,Acceptance and commitment therapy ,Relational frame theory ,Cognitive behavioral therapy ,03 medical and health sciences ,Psychiatry and Mental health ,Clinical Psychology ,0302 clinical medicine ,Empirical research ,medicine ,0501 psychology and cognitive sciences ,Psychology ,030217 neurology & neurosurgery ,Functional movement ,Clinical psychology - Abstract
Although there are many theories of functional movement disorders (FMD), the causes and prognosis remain unclear, and there are no treatments with high-quality empirical support. Acceptance and commitment therapy (ACT) is an acceptance-based behavior therapy which, via altering a process called psychological flexibility, aims to support behaviors that are consistent with a person’s overarching values—even in difficult, uncertain, or immutable contexts. It may, therefore, have pragmatic benefits in the context of FMD. We outline the theoretical basis for ACT and detail a case study of a brief (six session) intervention for increasing personally meaningful activity with FMD. The participant was in her early 20s and had been diagnosed with functional propriospinal myoclonus. ACT techniques including relational framing, defusion, and mindfulness exercises were used to increase psychological flexibility, with the goal of enabling effective functioning within the difficult context created by FMD. Following treatment, the participant showed a reliable change/clinical recovery in psychological flexibility (Acceptance and Action Questionnaire II [AAQ-II]), FMD symptom interference (Work and Social Adjustment Scale [WSAS]; primary outcome), and mood (Clinical Outcomes in Routine Evaluation 10-item scale [CORE-10]; secondary outcome). This case study demonstrates an approach that focuses first on improving functioning with FMD, as opposed to eliminating or controlling symptoms.
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- 2017
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233. Longitudinal monitoring of patient limb loading throughout ankle fracture rehabilitation using an insole load monitoring system: a case series
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Kylee North, Tomasz J. Petelenz, Ami R. Stuart, Robert W. Hitchcock, Erik N. Kubiak, Arad Lajevardi-Khosh, and David L. Rothberg
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030222 orthopedics ,030506 rehabilitation ,medicine.medical_specialty ,Rehabilitation ,Trimalleolar fracture ,business.industry ,medicine.medical_treatment ,Monitoring system ,General Medicine ,medicine.disease ,medicine.disease_cause ,Weight-bearing ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,medicine.anatomical_structure ,medicine ,Fracture (geology) ,Physical therapy ,Ankle ,0305 other medical science ,business ,Limb loading - Published
- 2017
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234. Allocation of Deceased Donor Kidneys for Transplantation: Opinions of Patients With CKD
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Geddes, Colin C., Rodger, R. Stuart C., Smith, Christopher, and Ganai, Anita
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- 2005
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235. Author correction : 420,000 year assessment of fault leakage rates shows geological carbon storage is secure
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Andrea Schroeder-Ritzrau, Johannes M. Miocic, Neil Burnside, R. Stuart Haszeldine, Norbert Frank, and Stuart Gilfillan
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0301 basic medicine ,Multidisciplinary ,Published Erratum ,lcsh:R ,lcsh:Medicine ,Colorado plateau ,Volcanism ,Co2 storage ,03 medical and health sciences ,Carbon storage ,030104 developmental biology ,0302 clinical medicine ,TA170 ,lcsh:Q ,Physical geography ,Author Correction ,lcsh:Science ,030217 neurology & neurosurgery ,Geology - Abstract
This Article contains errors in the Reference list. Reference 3 is incorrectly listed as ‘Song, J. & Zhang, D. Comprehensive Review of Caprock-Sealing Mechanisms for Geologic Carbon Sequestration. 47, 9–22 (2012)’. The correct reference is listed below as ref. 1. Reference 16 is incorrectly listed as ‘Gilfillan, S. M. V. et al. The noble gas geochemistry of natural CO2 gas reservoirs from the Colorado Plateau and Rocky Mountain provinces. USA. 72, 1174–1198 (2008)’. The correct reference is listed below as ref. 2. Reference 20 is incorrectly listed as ‘Alcalde, J. et al. Quantifying geological CO2 storage security to deliver on climate mitigation (2018)’. The correct reference is listed below as ref. 3. Reference 32 is incorrectly listed as ‘Condit, C. D. & Connor, C. B. Recurrence rates of volcanism in basaltic volcanic fields: An example from the Springerville volcanic field. Arizona. 108, 1225–1241 (1996)’. The correct reference is listed below as ref. 4.
- Published
- 2020
236. Constraining the Subsurface Geochemical Baseline of CMC Research Institutes’ Field Research Station (FRS), Alberta
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Rachel Utley, Nicholas Utting, Gareth Johnson, Marta Zurakowski, Domokos Györe, Finlay Stuart, Kirk Osadetz, Thomas Darrah, R. Stuart Haszeldine, and Stuart Gilfillan
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- 2020
- Full Text
- View/download PDF
237. Infrared Absorption Spectra of Some Aldofuranoid, Aldopyranoid, and Acyclic l-Acylamido Derivatives of Sugars
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Tipson, R. Stuart, Cerezo, Alberto S., Deulofeu, Venancio, and Cohen, Alex
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Physics and Chemistry - Abstract
The infrared absorption spectra of two glycofuranosylacetamides and their perbenzoates, and of eleven glycopyranosylacylamides and eight esters thereof, are presented and discussed. For comparison, the spectra of thirteen 1,1-bis(acylamido)-1-deoxyalditols and eight esters thereof are also given and discussed. The useful correlations between structure and infrared absorption made by Barker and co-workers for certain carbohydrates, and by Nanasi and co-workers for some N-arylglycosylamines, cannot be extended to the 1-acylamido compounds we have studied. Certain of Verstraeten’s correlations may have some diagnostic value.
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- 2019
238. Getting CO2 Storage Right – Arithmetically and Politically
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R. Stuart Haszeldine
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Effects of global warming ,Software deployment ,Obstacle ,Carbon capture and storage (timeline) ,Limit (mathematics) ,Business ,Co2 storage ,Environmental economics - Abstract
Carbon capture and storage (CCS) is proposed as essential in efforts to limit the effects of climate change. CCS is now recognised as “essential, not optional” on the pathway to recover already emitted CO2 and achieve net-negative industrial economies. All aspects of CCS have been established theoretically, experimentally and by pilot trials. The obstacle to deployment is political and economic understanding.
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- 2019
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239. Iodane-Guided C-H Cleavage to Synthesize Densely Functionalized Arenes
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Aleksandra Nilova, David R. Stuart, Paul Ha-Yeon Cheong, Kevin S. Brown, H. Camille Richardson, Gisela Gonzalez-Monteil, Paul A. Sibbald, and Edward J. Valente
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Steric effects ,chemistry.chemical_compound ,Chemistry ,Aryl ,Regioselectivity ,Surface modification ,Reactivity (chemistry) ,Cleavage (embryo) ,Resonance (chemistry) ,Combinatorial chemistry ,Aryne - Abstract
We describe a strategy for the iodane-guided functionalization of sterically congested C-H bonds, which is distinct from electronic, steric or proximity guided C-H functionalization methods. Readily accessible aryl(Mes)iodonium salts serve as the starting materials in these reactions and produce complex 1,2,3,4-substituted arenes via aryne intermediates. This approach is especially powerful when coupled with the innate C-H functionalization reactivity of simple arenes, to replace two C-H bonds with two C-C or C-heteroatom bonds while over-riding steric effects that typically inhibit such reactions. DFT stud-ies reveal a contribution of inductive, resonance, and steric effects on the regioselectivity of C-H cleavage and aryne generatation.
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- 2019
- Full Text
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240. The effect of audiovisual distraction on patient-controlled sedation under spinal anesthesia: a prospective, randomized trial
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Adam W, Meier, Michael J, Buys, Manasa, Gill, Eric W, Piacenza, Linda, Nguyen, Chelsea M, Allen, Ami R, Stuart, Jeremy, Gililland, and Ken B, Johnson
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Conscious Sedation ,Humans ,Hypnotics and Sedatives ,Prospective Studies ,Anesthesia, Spinal ,Propofol - Abstract
Audiovisual distraction (AVD) has been used to augment or replace procedural sedation. We investigated whether AVD in patients having total hip (THA) or total knee arthroplasty (TKA) under spinal anesthesia would reduce self-administered propofol consumption during surgery. 50 participants were randomized equally into a patient-controlled sedation (PCS) group or AVD group. All participants were given a spinal block and a propofol PCS device prior to surgery. In addition, Group AVD participants selected and watched a movie or documentary film on a tablet device with noise-cancelling headphones during surgery. The primary outcome of this study was total propofol consumption standardized as mcg/kg/min. Secondary outcomes evaluated increased supplemental oxygen use, rescue airway interventions, hypotension, disruptive movement events during surgery, sedation, and satisfaction with anesthesia scores. Historical clinician-controlled propofol usage at our institution over the previous 2 years were recorded. There was no significant difference in median propofol consumption between Groups PCS and AVD, 8.4 mcg/kg/min (1.6-18.9) vs 4 mcg/kg/min (0-9) (P = 0.29), respectively. Historical clinician-controlled usage of propofol demonstrated a median of 39.3 mcg/kg/min (29.2-51.2). There were few differences in the secondary outcome measures. The use of AVD did not reduce patient-controlled propofol consumption in patients having a THA or TKA surgery under spinal anesthesia.
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- 2019
241. Community outbreak of hepatitis A disproportionately affecting men who have sex with men in Toronto, Canada, January 2017-November 2018
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S Ota, A Andonov, V Dubey, M Benusic, R Stuart, H Sachdeva, and J Maclachlan
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medicine.medical_specialty ,education.field_of_study ,Outbreak Report ,business.industry ,Transmission (medicine) ,Public health ,viruses ,Population ,Outbreak ,Hepatitis A ,virus diseases ,General Medicine ,medicine.disease ,Men who have sex with men ,Vaccination ,Environmental health ,Epidemiology ,medicine ,business ,education - Abstract
BACKGROUND: In late 2016 and early 2017, a number of countries began reporting hepatitis A virus (HAV) outbreaks involving person-to-person transmission among men who have sex with men (MSM), people using illicit drugs and homeless or underhoused persons. OBJECTIVE: To describe the epidemiology and public health response to an outbreak of HAV disproportionately affecting MSM in Toronto, Canada from January 2017 to November 2018. METHODS: Following an increase in the number of cases of HAV in MSM being reported in other countries, enhanced surveillance was performed for all non-travel-related cases of HAV reported from June 1, 2017 to November 1, 2018, including a retrospective analysis of cases reported from January 2017 to June 2017. Descriptive analysis and viral sequencing were performed to describe person-to-person transmission patterns and target interventions. Control strategies included interventions to promote the uptake of preexposure HAV vaccination, including social media campaigns geared to MSM, messaging to healthcare providers and vaccine clinics. RESULTS: Based on the outbreak case definitions, 52 confirmed and probable cases of HAV were identified. Over 80% of outbreak cases were male (n=43/52) and, among those for whom data were available, 64% (n=25/39) reported an MSM exposure. Data on hospitalization was available for 51 cases; 56% of confirmed cases (n=23/41) and 40% of probable cases (n=4/10) required hospitalization. Of the cases with serum samples that had HAV sequencing, 83% (n=30/36) had one of the three strains seen circulating in outbreaks among MSM internationally; 72% (n=26/36) were VRD_521_2016, which had been detected in recently reported European outbreaks among MSM. Targeted promotion of publicly-funded vaccination using social media platforms popular with MSM and targeted vaccine clinics were developed to promote HAV awareness and vaccine uptake among MSM. CONCLUSION: Outbreaks of HAV, attributed to person-to-person transmission of strains of HAV that disproportionately affected MSM and were likely to have been imported from international MSM outbreaks, have now occurred in Canada. Genetic sequencing of HAV, risk factor analysis of cases, monitoring trends of vaccine coverage in high-risk groups and initiation of vaccination campaigns that address barriers to HAV preexposure vaccine coverage in the MSM population may prevent future outbreaks.
- Published
- 2019
242. Assessing Femoral Rotation: A Survey Comparison of Techniques
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Thomas F. Higgins, David L. Rothberg, Ami R. Stuart, Justin M. Haller, Lucas S. Marchand, and Lance G. Jacobson
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Orthodontics ,030222 orthopedics ,Rotation ,business.industry ,Femoral shaft ,Horizontal angle ,030208 emergency & critical care medicine ,General Medicine ,Femoral osteotomy ,Femoral rotation ,True lateral ,Osteotomy ,03 medical and health sciences ,0302 clinical medicine ,Lesser Trochanter ,Fluoroscopy ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Femur ,business ,Cadaveric spasm ,Femoral Fractures - Abstract
OBJECTIVES To compare 3 common techniques for assessing femoral malrotation through a response analysis. METHODS Ten intact human cadaveric pelvis-to-knee specimens were used to create a fracture model. A mobile C-arm x-ray system was used to capture images of an intact control femur and a contralateral test femur on each specimen. A midshaft femoral osteotomy was created on the test femur and it was then internally and externally rotated in 5-degree intervals up to 20 degrees. Images were obtained and stored at each increment of malrotation. Eight surveys of 20-paired images each were generated and presented for surgeon review. Accuracy of predicting femoral malrotation using the true lateral technique (TLT), neck horizontal angle (NHA) method, and lesser trochanter profile (LTP) was measured. RESULTS Eighty-five surgeons completed a survey with 80 surgeons (94%) acknowledging the use of a described fluoroscopic method for assisting with rotational alignment. Surgeons correctly accepted a fracture rotated less than 20 degrees and rejected a fracture rotated 20 degrees or more 63% of the time. The ability to correctly identify 20 degrees of malrotation varied per technique used to assess rotation. With the LTP and NHA method, 67% of surgeons responded correctly. Surgeons performed significantly worse when using the TLT with only 53% providing correct responses (P < 0.0001). CONCLUSIONS Surgeons using described fluoroscopic methods to identify acceptable rotation in femoral shaft fractures are correct 63% of the time. The LTP and NHA techniques are equally reliable and more effective than the TLT at detecting clinically significant femoral malrotation.
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- 2019
243. A pharmacokinetic-pharmacodynamic real-time display may change anesthesiologists' behavior
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Shinju, Obara, Noah, Syroid, Takahiro, Ogura, Nathan L, Pace, Ken B, Johnson, Rob, Albert, Jim, Agutter, Ami R, Stuart, and Talmage D, Egan
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Fentanyl ,Isoflurane ,Anesthesia Recovery Period ,Humans ,Anesthesia, General ,Anesthesiologists - Abstract
We have developed a real-time graphical display that presents anesthetic pharmacology data (drug effect site concentrations (Ce) and probability of anesthetic effects including hypnosis, loss of response to tracheal intubation), improving a previous prototype. We hypothesized that the use of the display alters (1) clinical behavior of anesthesiologists (i.e., Ce of isoflurane and fentanyl at the end of anesthesia), (2) fentanyl dose during the first 30 min of recovery in the post anesthesia care unit (PACU), and that the response of clinicians to the display in terms of workload and utility is favorable. The display was evaluated in a two-group, non-randomized prospective observational study of 30 patients undergoing general anesthesia using isoflurane and fentanyl. The isoflurane-predicted Ce was lower in the display group (without-display: 0.64% ± 0.06%; with-display: 0.42 ± 0.04%; t
- Published
- 2019
244. Code and data for 'The Rise and Fall of the Note' (PACMHCI, CSCW 2019)
- Author
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Geiger, R. Stuart
- Abstract
This repo contains the code and data needed to reproduce the figures in a forthcoming paper (see paper/camera-ready-paper.pdf) in Proceedings of the ACM on Human-Computer Interaction -- the new journal venue for the proceedings of the ACM conference on Computer-Supported Cooperative Work (or CSCW). The entire study involved text analysis of copyrighted papers, which is not free to redistribute here. However, the notebook I used for processing the PDFs is available for reference at data-processing.ipynb. A data file containing all the quantitative statistics for each paper is at cscw-pages-notext.csv. This file is loaded by analysis-viz.ipynb, which processes it to produce the statistics and graphs presented in the paper. This notebook can also be run interactively for free in the cloud with Binder, so you can change various parameters or visualize it differently.
- Published
- 2019
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- View/download PDF
245. Code and data for 'The Rise and Fall of the Note' (PACMHCI, CSCW 2019)
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R. Stuart Geiger
- Abstract
This repo contains the code and data needed to reproduce the figures in a forthcoming paper (see paper/camera-ready-paper.pdf) in Proceedings of the ACM on Human-Computer Interaction -- the new journal venue for the proceedings of the ACM conference on Computer-Supported Cooperative Work (or CSCW). The entire study involved text analysis of copyrighted papers, which is not free to redistribute here. However, the notebook I used for processing the PDFs is available for reference at data-processing.ipynb. A data file containing all the quantitative statistics for each paper is at cscw-pages-notext.csv. This file is loaded by analysis-viz.ipynb, which processes it to produce the statistics and graphs presented in the paper. This notebook can also be run interactively for free in the cloud with Binder, so you can change various parameters or visualize it differently.
- Published
- 2019
- Full Text
- View/download PDF
246. Opioid-related beliefs and prescription modalities for postoperative pain of Dutch and American physicians
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Ken B. Johnson, Ami R. Stuart, Akiko Okifuji, Kai Kuck, Olivia Ac Lamers, and Mienke Rijsdijk
- Subjects
Cross-Cultural Comparison ,medicine.medical_specialty ,Opioid consumption ,Attitude of Health Personnel ,Postoperative pain ,media_common.quotation_subject ,Clinical Decision-Making ,Patient characteristics ,Pilot Projects ,03 medical and health sciences ,0302 clinical medicine ,030202 anesthesiology ,Surveys and Questionnaires ,Medicine ,Humans ,Medical prescription ,Practice Patterns, Physicians' ,media_common ,Netherlands ,Pain, Postoperative ,Modalities ,business.industry ,Addiction ,General Medicine ,United States ,Analgesics, Opioid ,Opioid ,Prescription opioid ,Family medicine ,Practice Guidelines as Topic ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Aim: Opioid consumption and addiction are increasing worldwide, yet the USA stands out for its high addiction rates and opioid-related deaths. Considering that patient characteristics are comparable across western countries, physicians' prescribing modalities may influence opioid consumption. We conducted a pilot study to examine opioid-related beliefs and prescription habits of Dutch and American physicians. Methods & materials: A survey was administered to 488 physicians who routinely prescribe opioids for postoperative pain. Results: A total of 75 (16%) physicians responded to the survey. When deciding to prescribe opioids, Dutch physicians adopted a patient-guided approach, whereas most American doctors followed strict guidelines and protocols. Conclusion: This study identified significant differences between Dutch and American physicians’ attitudes and prescribing modalities.
- Published
- 2019
247. Initial results from the New Horizons exploration of 2014 MU 69 , a small Kuiper Belt object
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J. Fischetti, S. Bhaskaran, Matthias Hahn, Karl Whittenburg, Derek S. Nelson, G. A. Griffith, Amanda M. Zangari, B. J. Buratti, James T. Keane, E. J. Lessac-Chenen, Ralph L. McNutt, Tiffany J. Finley, J. Scherrer, M. A. Ritterbush, M. M. Saina, G. Dunn, T. A. Hill, J. Van Eck, T. Stryk, J. M. Albers, D. C. Reuter, C. M. Dalle Ore, H. A. Elliott, D. J. Schultz, J. Andrews, Douglas P. Hamilton, M. H. Versteeg, Orkan M. Umurhan, Matthew E. Hill, Hai Nguyen, M. Simon, L. Gabasova, D. E. Jennings, D. J. Katz, J. E. Riedel, N. Behrooz, M. N. Fosbury, Henry B. Throop, A. J. Verbiscer, E. Bernardoni, Ross A. Beyer, C. Engelbrecht, Francesca Scipioni, H. L. Winters, Thomas H. Zurbuchen, Carey M. Lisse, Veronica J. Bray, M. G. Ryschkewitsch, Stuart J. Robbins, S. E. Jaskulek, M. C. Kochte, Thomas Mehoke, M. S. Lahr, M. J. Salinas, V. A. Mallder, S. P. Williams, B. H. May, D. M. Mages, C. C. Deboy, Simon B. Porter, Gerhard Kruizinga, Marc W. Buie, Jorge I. Nunez, John Hayes, Peter Kollmann, P. Dharmavaram, J. M. Moore, Darrell F. Strobel, John Stansberry, R. P. Binzel, H. M. Hart, Jillian Redfern, E. W. Stahlheber, H. K. Kang, James L. Green, Anthony F. Egan, Carly Howett, Fran Bagenal, Dale Stanbridge, Chris B. Hersman, C. L. Chavez, Debi Rose, J. Y. Pelgrift, Maria E. Banks, D. C. Schurr, Matthew R. Buckley, L. S. Turner, Ivan Linscott, Kaj E. Williams, J. Eisig, Mihaly Horanyi, Matthew Jones, Mark R. Showalter, William B. McKinnon, Leslie A. Young, E. J. Colwell, Daniel T. Britt, Kirby Runyon, David J. McComas, G. Weigle, Bernard Schmitt, Susan D. Benecchi, Alissa M. Earle, M. J. Kinczyk, Tod R. Lauer, M. R. Piquette, Lori S. Glaze, Carver J. Bierson, L. M. Burke, Brian Carcich, O. S. Custodio, A. Harch, Harold A. Weaver, Dale P. Cruikshank, Oliver L. White, L. E. Brown, William M. Grundy, G. K. Oxton, Chelsea L. Ferrell, David E. Kaufmann, Mohamed Ramy El-Maarry, K. A. Harmon, W. R. Schlei, Eric Quirico, Derek C. Richardson, J. M. Freeze, Jennifer Hanley, R. G. Shelton, Andrew J. Steffl, Mike Bird, H. W. Taylor, Harold J. Reitsema, Stamatios M. Krimigis, D. R. Boone, E. D. Fattig, A. L. Regiec, D. J. Rodgers, Jason D. Hofgartner, D. Velez, Catherine B. Olkin, Kelsi N. Singer, Brian Bauer, Carl J. Ercol, Martin Pätzold, Nicole Martin, Stewart Bushman, J. Firer, Allen W. Lunsford, R. W. Webbert, A. L. Chaikin, Alex Parker, C. A. Conrad, M. P. Conner, S. B. Cooper, Chloe B. Beddingfield, William M. Folkner, J. E. Lee, M. B. Tapley, G. R. Gladstone, D. A. Aguilar, Glen H. Fountain, Emma Birath, Rebecca Sepan, Jeremy Bauman, J. Wm. Parker, S. Weidner, J. R. Jensen, Jason C. Cook, Alan D. Howard, William M. Owen, Andrew F. Cheng, B. L. Enke, Sarah A. Hamilton, Tom Andert, K. B. Beisser, K. E. Bechtold, J. R. Wendel, Rajani D. Dhingra, Paul M. Schenk, Michael E. Summers, J. R. Spencer, D. W. Hals, Silvia Protopapa, A. C. Ocampo, Mark E. Holdridge, S. A. Stern, A. Taylor, R. M. Tedford, G. P. Keleher, Gabe Rogers, Frederic Pelletier, Jj Kavelaars, Yanping Guo, Jon Pineau, Steven J. Conard, Alice Bowman, A. Hosadurga, B. G. Williams, Michael Vincent, David Y. Kusnierkiewicz, Paul E. Rosendall, G. B. Lawrence, J. R. Stuart, M. M. Stothoff, Jr. D. S. Mehoke, Southwest Research Institute [Boulder] (SwRI), Johns Hopkins University Applied Physics Laboratory [Laurel, MD] (APL), Lowell Observatory [Flagstaff], Space Physics Research Laboratory [Ann Arbor] (SPRL), University of Michigan [Ann Arbor], University of Michigan System-University of Michigan System, SwRI Planetary Science Directorate [Boulder], Universitat de Lleida, Institut für Raumfahrttechnik, Universität der Bundeswehr München [Neubiberg], Laboratory for Atmospheric and Space Physics [Boulder] (LASP), University of Colorado [Boulder], Department of Space Studies [Boulder], Rheinische Friedrich-Wilhelms-Universität Bonn, Jet Propulsion Laboratory (JPL), NASA-California Institute of Technology (CALTECH), Institut de Planétologie et d'Astrophysique de Grenoble (IPAG), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG ), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national des sciences de l'Univers (INSU - CNRS)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Institute of Hydrology, NASA Goddard Space Flight Center (GSFC), Department of Physics, Chemistry and Biology [Linköping] (IFM), Linköping University (LIU), Africa Rice Center [Bénin] (AfricaRice), Africa Rice Center [Côte d'Ivoire] (AfricaRice), Consultative Group on International Agricultural Research [CGIAR] (CGIAR)-Consultative Group on International Agricultural Research [CGIAR] (CGIAR), Yonsei University, Galaxies, Etoiles, Physique, Instrumentation (GEPI), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre International de Hautes Etudes Agronomiques Méditerranéennes - Institut Agronomique Méditerranéen de Montpellier (CIHEAM-IAMM), Centre International de Hautes Études Agronomiques Méditerranéennes (CIHEAM), Princeton University, Reed College, Hanoi National University of Education (HNUE), Rhenish Institute for Environmental Research (RIU), University of Cologne, School of Earth, Atmospheric and Environmental Sciences [Manchester] (SEAES), University of Manchester [Manchester], ESA, Southwest Research Institute [San Antonio] (SwRI), NASA Ames Research Center (ARC), Laboratoire pour l'utilisation du rayonnement électromagnétique (LURE), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-MENRT-Centre National de la Recherche Scientifique (CNRS), Lunar and Planetary Laboratory [Tucson] (LPL), University of Arizona, Johns Hopkins University (JHU), Institute of Physics of the Czech Academy of Sciences (FZU / CAS), Czech Academy of Sciences [Prague] (CAS), Laboratoire de Chimie Analytique Bio-Inorganique et Environnement (LCABIE), Université de Pau et des Pays de l'Adour (UPPA)-Centre National de la Recherche Scientifique (CNRS), Department of Biochemistry, Faculty of Biology, University of Warmia and Mazury [Olsztyn], California Institute of Technology (CALTECH)-NASA, Centre National d'Études Spatiales [Toulouse] (CNES)-Observatoire des Sciences de l'Univers de Grenoble (OSUG ), Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Grenoble Alpes (UGA), University of Warmia and Mazury, Institut de Mécanique Céleste et de Calcul des Ephémérides (IMCCE), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), inconnu temporaire UPEMLV, Inconnu, INGENIERIE (INGENIERIE), Institut de recherches sur la catalyse et l'environnement de Lyon (IRCELYON), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Génie des Procédés Plasmas et Traitement de Surface (ENSCP), PARIS, Africa Rice Center, Africa Rice Center (AfricaRice), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS), PSL Research University (PSL)-PSL Research University (PSL)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), PSL Research University (PSL)-PSL Research University (PSL)-Centre National de la Recherche Scientifique (CNRS), Centre National d'Études Spatiales [Toulouse] (CNES)-Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire des Sciences de l'Univers de Grenoble (OSUG), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP)-Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)-Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS), Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institute of Physics of Academy of Sciences of Czech Republic, and Czech Academy of Sciences [Prague] (ASCR)
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Earth and Planetary Astrophysics (astro-ph.EP) ,Solar System ,Multidisciplinary ,010504 meteorology & atmospheric sciences ,Spacecraft ,business.industry ,[SDU.ASTR.EP]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Earth and Planetary Astrophysics [astro-ph.EP] ,FOS: Physical sciences ,Astronomy ,Coma (optics) ,Contact binary ,Albedo ,01 natural sciences ,Object (philosophy) ,Solar wind ,13. Climate action ,0103 physical sciences ,Pebble ,business ,010303 astronomy & astrophysics ,Geology ,ComputingMilieux_MISCELLANEOUS ,Astrophysics - Earth and Planetary Astrophysics ,0105 earth and related environmental sciences - Abstract
The Kuiper Belt is a distant region of the Solar System. On 1 January 2019, the New Horizons spacecraft flew close to (486958) 2014 MU69, a Cold Classical Kuiper Belt Object, a class of objects that have never been heated by the Sun and are therefore well preserved since their formation. Here we describe initial results from these encounter observations. MU69 is a bi-lobed contact binary with a flattened shape, discrete geological units, and noticeable albedo heterogeneity. However, there is little surface color and compositional heterogeneity. No evidence for satellites, ring or dust structures, gas coma, or solar wind interactions was detected. By origin MU69 appears consistent with pebble cloud collapse followed by a low velocity merger of its two lobes., 43 pages, 8 figure
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- 2019
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248. Resistance to Adoption of Best Practices
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Dan Sholler, Sara Stoudt, Chris J. Kennedy, Fernando Hoces de la Guardia, Francois Lanusse, Karthik Ram, Kellie Ottoboni, Marla Stuart, Maryam Vareth, Nelle Varoquaux, Rebecca Barter, R. Stuart Geiger, Scott Peterson, and Stefan van der Walt
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bepress|Social and Behavioral Sciences|Sociology|Work, Economy and Organizations ,bepress|Social and Behavioral Sciences|Sociology ,SocArXiv|Social and Behavioral Sciences|Sociology ,SocArXiv|Social and Behavioral Sciences|Sociology|Organizations, Occupations, and Work ,SocArXiv|Social and Behavioral Sciences|Library and Information Science ,bepress|Social and Behavioral Sciences ,SocArXiv|Social and Behavioral Sciences ,bepress|Social and Behavioral Sciences|Science and Technology Studies ,SocArXiv|Social and Behavioral Sciences|Science and Technology Studies ,bepress|Social and Behavioral Sciences|Library and Information Science - Abstract
There are many recommendations of "best practices" for those doing data science, data-intensive research, and research in general. These documents usually present a particular vision of how people should work with data and computing, recommending specific tools, activities, mechanisms, and sensibilities. However, implementation of best (or better) practices in any setting is often met with resistance from individuals and groups, who perceive some drawbacks to the proposed changes to everyday practice. We offer some definitions of resistance, identify the sources of researchers' hesitancy to adopt new ways of working, and describe some of the ways resistance is manifested in data science teams. We then offer strategies for overcoming resistance based on our group members' experiences working alongside resistors or resisting change themselves. Our discussion concluded with many remaining questions left to tackle, some of which are listed at the end of this piece.
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- 2019
249. Best Practices for Managing Turnover in Data Science Groups, Teams, and Labs
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Geiger, R. Stuart, Sholler, Dan, Hoffman, Chris, Lanusse, Francois, Hoces de la Guardia, Fernando, Varoquaux, Nelle, Stoudt, Sara, McDevitt, Shana, Garcia, Rolando, Peterson, Scott, and Das, Diya
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bepress|Social and Behavioral Sciences|Sociology ,bepress|Social and Behavioral Sciences|Sociology|Work, Economy and Organizations ,SocArXiv|Social and Behavioral Sciences|Sociology ,SocArXiv|Social and Behavioral Sciences|Sociology|Organizations, Occupations, and Work ,SocArXiv|Social and Behavioral Sciences|Library and Information Science ,bepress|Social and Behavioral Sciences ,SocArXiv|Social and Behavioral Sciences ,bepress|Social and Behavioral Sciences|Science and Technology Studies ,SocArXiv|Social and Behavioral Sciences|Science and Technology Studies ,bepress|Social and Behavioral Sciences|Library and Information Science - Abstract
Turnover is a fact of life for any project, and academic research teams can face particularly high levels of people who come and go through the duration of a project. In this article, we discuss the challenges of turnover and some potential practices for helping manage it, particularly for computational- and data-intensive research teams and projects. The topics we discuss include establishing and implementing data management plans, file and format standardization, workflow and process documentation, clear team roles, and check-in and check-out procedures.
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- 2019
250. Short Versus Long Cephalomedullary Nails for Fixation of Stable Versus Unstable Intertrochanteric Femur Fractures at a Level 1 Trauma Center
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David L. Rothberg, Jeremy M. Gililland, Ami R. Stuart, Erik N. Kubiak, Angela P. Presson, Michael J. Beebe, D. Andrew Hulet, Chong Zhang, and Casey S. Whale
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Adult ,Male ,medicine.medical_specialty ,Stable fracture ,Bone Nails ,Prosthesis Design ,Young Adult ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,Trauma Centers ,Fracture fixation ,Humans ,Medicine ,Orthopedics and Sports Medicine ,Femur ,030212 general & internal medicine ,Unstable fracture ,skin and connective tissue diseases ,Aged ,Retrospective Studies ,Aged, 80 and over ,030222 orthopedics ,integumentary system ,Adult patients ,Hip Fractures ,business.industry ,Trauma center ,Middle Aged ,Fracture Fixation, Intramedullary ,Surgery ,Orthopedic surgery ,Female ,business ,Follow-Up Studies - Abstract
The purpose of this study was to compare failure and complication rates associated with short cephalomedullary nail vs long cephalomedullary nail fixation for stable vs unstable intertrochanteric femur fractures. This study included 201 adult patients with nonpathologic intertrochanteric femur fractures without subtrochanteric extension (OTA 31-A1.1-3, 31-A2.1-3, 31-A3.1-3) who were treated with a short cephalomedullary nail (n=70) or a long cephalomedullary nail (n=131) and had at least 6 months of follow-up. Treatment groups were similar in terms of age, sex, and comorbidities. In the stable fracture group (N=81), there was no difference in total complications (adjusted P =.73), failure (adjusted P =.78), or mortality (adjusted P =.62) between short cephalomedullary nails and long cephalomedullary nails. Unstable fracture patterns were more likely to be treated with a long cephalomedullary nail than a short cephalomedullary nail ( P =.01). In the unstable fracture group (N=120), there was no difference in total complications (adjusted P =.32) or failure (adjusted P =.31) between short cephalomedullary nails and long cephalomedullary nails. A cumulative mortality curve showed a trend toward increasing mortality in unstable fractures treated with short cephalomedullary nails. Traumatologists did not display a statistically significant preference between short cephalomedullary nails and long cephalomedullary nails when compared with nontraumatologists. [ Orthopedics . 2019; 42(2):e202–e209.]
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- 2019
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