201. GeneMANIA: Fast gene network construction and function prediction for Cytoscape
- Author
-
Harold Rodriguez, Khalid Zuberi, Quaid Morris, Jason Montojo, and Gary D. Bader
- Subjects
Data source ,General Immunology and Microbiology ,Gene ontology ,Bioinformatics ,Gene regulatory network ,General Medicine ,Computational biology ,Construct (python library) ,Articles ,Biology ,Plant biology ,General Biochemistry, Genetics and Molecular Biology ,Interaction network ,General Pharmacology, Toxicology and Pharmaceutics ,Software Tool ,Neuroscience ,Function (biology) - Abstract
The GeneMANIA Cytoscape app enables users to construct a composite gene-gene functional interaction network from a gene list. The resulting network includes the genes most related to the original list, and functional annotations from Gene Ontology. The edges are annotated with details about the publication or data source the interactions were derived from. The app leverages GeneMANIA’s database of 1800+ networks, containing over 500 million interactions spanning 8 organisms: A. thaliana, C. elegans, D. melanogaster, D. rerio, H. sapiens, M. musculus, R. norvegicus, and S. cerevisiae. Users may also import their own organisms, networks, and expression profiles. The app is compatible with Cytoscape versions 2 and 3.
- Published
- 2014