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94,776 results on '"Popescu, A."'

205. Perioperative Lymphopenia is Associated with Increased Risk of Recurrence and Worse Survival Following Hepatectomy for Hepatocellular Carcinoma

Author

Tsilimigras, Diamantis I., Endo, Yutaka, Ratti, Francesca, Marques, Hugo P., Cauchy, François, Lam, Vincent, Poultsides, George A., Popescu, Irinel, Alexandrescu, Sorin, Martel, Guillaume, Kitago, Minoru, Guglielmi, Alfredo, Hugh, Tom, Aldrighetti, Luca, Gleisner, Ana, Shen, Feng, Endo, Itaru, and Pawlik, Timothy M.

Published
2024
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207. Nonvolatile Tuning of Bragg Structures Using Transparent Phase-Change Materials

Author

Nobile, Nicholas A., Lian, Chuanyu, Sun, Hongyi, Huang, Yi-Siou, Mills, Brian, Popescu, Cosmin Constantin, Callahan, Dennis, Hu, Juejun, Ocampo, Carlos A. Ríos, and Youngblood, Nathan

Subjects
Physics - Optics
Abstract

Bragg gratings offer high-performance filtering and routing of light on-chip through a periodic modulation of a waveguide's effective refractive index. Here, we model and experimentally demonstrate the use of Sb2Se3, a nonvolatile and transparent phase-change material, to tune the resonance conditions in two devices which leverage periodic Bragg gratings: a stopband filter and Fabry-Perot cavity. Through simulations, we show that similar refractive indices between silicon and amorphous Sb2Se3 can be used to induce broadband transparency, while the crystalline state can enhance the index contrast in these Bragg devices. Our experimental results show the promise and limitations of this design approach and highlight specific fabrication challenges which need to be addressed in future implementations.

Published
2023

208. A simple and self-contained proof for the Lindemann-Weierstrass theorem

Author

Popescu, Sever Angel

Subjects
Mathematics - Number Theory, 11J81 (Primary), 11J99 (Secondary)
Abstract

The famous result of Lindemann and Weierstrass says that if $a_{1},a_{2},\ldots,a_{n}$ are distinct algebraic numbers, then $e^{a_{1}},e^{a_{2}},\ldots,e^{a_{n}}$ are linearly independent complex numbers over the field $\overline{\mathbb{Q}}$ of all algebraic numbers. Starting from some basic ideas of Hermite, Lindemann, Hilbert, Hurwitz and Baker, in this note we provide an easy to understand and self-contained proof for the Lindemann-Weierstrass Theorem. In an introductory section we have gathered all the algebraic number theory tools that are necessary to prove the main theorem. All these auxiliary results are fully proved in a simple and elementary way, so that the paper can be read even by an undergraduate student., Comment: 17 pages, minor corrections and latex updates

Published
2023

209. Comparison of optical spectra between asteroids Ryugu and Bennu:I. Cross calibration between Hayabusa2/ONC-T and OSIRIS-REx/MapCam

Author

Yumoto, K., Tatsumi, E., Kouyama, T., Golish, D. R., Cho, Y., Morota, T., Kameda, S., Sato, H., Rizk, B., DellaGiustina, D. N., Yokota, Y., Suzuki, H., de Leon, J., Campins, H., Licandro, J., Popescu, M., Rizos, J. L., Honda, R., Yamada, M., Sakatani, N., Honda, C., Matsuoka, M., Hayakawa, M., Sawada, H., Ogawa, K., Yamamoto, Y., Lauretta, D. S., and Sugita, S.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

Asteroids (162173) Ryugu and (101955) Bennu observed by Hayabusa2 and OSIRIS-REx share many properties, but spectral observations by the telescopic Optical Navigation Camera (ONC-T) and MapCam detected subtle but significant differences, which may reflect differences in their origin and evolution. Comparing these differences on the same absolute scale is necessary for understanding their causes. However, ONC-T and MapCam have a large imager-to-imager systematic error of up to 15% caused by the difference in radiometric calibration targets. To resolve this problem, we cross calibrated albedo and color data between the two instruments using the Moon as the common calibration standard. The images of the Moon taken by ONC-T and MapCam were compared with those simulated using photometry models developed from lunar orbiter data. Our results show that the cross-calibrated reflectance of Ryugu and Bennu can be obtained by upscaling the pre-cross-calibrated reflectance of Bennu by 13.3 +/- 1.6% at b band, 13.2 +/- 1.5% at v band, 13.6 +/- 1.7% at w band, and 14.8 +/- 1.8% at x band, while those for Ryugu are kept the same. These factors compensate for the imager-to-imager bias caused by differences in targets used for radiometric calibration and solar irradiance models used for data reduction. Need for such large upscaling underscore the importance of using the cross-calibrated data for accurately comparing the Ryugu and Bennu data. The uncertainty in these factors show that the reflectance of Ryugu and Bennu can be compared with <2% accuracy after applying our results. By applying our cross calibration, the geometric albedo of Bennu became consistent with those observed by ground-based telescopes and OVIRS. Our result can be simply applied by multiplying a constant to the publicly available data and enables accurate comparison of the optical spectra of Ryugu and Bennu in future studies.

Published
2023
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210. Self-Distilled Masked Auto-Encoders are Efficient Video Anomaly Detectors

Author

Ristea, Nicolae-Catalin, Croitoru, Florinel-Alin, Ionescu, Radu Tudor, Popescu, Marius, Khan, Fahad Shahbaz, and Shah, Mubarak

Subjects
Computer Science - Computer Vision and Pattern Recognition, Computer Science - Machine Learning
Abstract

We propose an efficient abnormal event detection model based on a lightweight masked auto-encoder (AE) applied at the video frame level. The novelty of the proposed model is threefold. First, we introduce an approach to weight tokens based on motion gradients, thus shifting the focus from the static background scene to the foreground objects. Second, we integrate a teacher decoder and a student decoder into our architecture, leveraging the discrepancy between the outputs given by the two decoders to improve anomaly detection. Third, we generate synthetic abnormal events to augment the training videos, and task the masked AE model to jointly reconstruct the original frames (without anomalies) and the corresponding pixel-level anomaly maps. Our design leads to an efficient and effective model, as demonstrated by the extensive experiments carried out on four benchmarks: Avenue, ShanghaiTech, UBnormal and UCSD Ped2. The empirical results show that our model achieves an excellent trade-off between speed and accuracy, obtaining competitive AUC scores, while processing 1655 FPS. Hence, our model is between 8 and 70 times faster than competing methods. We also conduct an ablation study to justify our design. Our code is freely available at: https://github.com/ristea/aed-mae., Comment: Accepted at CVPR 2024

Published
2023

211. Discovery and physical characterization as the first response to a potential asteroid collision: The case of 2023 DZ2

Author

Popescu, Marcel M., Văduvescu, O., de León, Julia, Marcos, C. de la Fuente, Marcos, R. de la Fuente, Stănescu, M. O., Alarcon, M. R., Ricart, M. Serra, Licandro, J., Berteşteanu, D., Predatu, M., Curelaru, L., Barwell, F., Jhass, K., Boldea, C., Macías, A. Aznar, Hudin, L., and Dumitru, B. A.

Subjects
Astrophysics - Earth and Planetary Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Near-Earth asteroids (NEAs) that may evolve into impactors deserve detailed threat assessment studies. Early physical characterization of a would-be impactor may help in optimizing impact mitigation plans. We first detected NEA 2023~DZ$_{2}$ on 27--February--2023. After that, it was found to have a Minimum Orbit Intersection Distance (MOID) with Earth of 0.00005~au as well as an unusually high initial probability of becoming a near-term (in 2026) impactor. We aim to perform a rapid but consistent dynamical and physical characterization of 2023~DZ$_{2}$ as an example of a key response to mitigate the consequences of a potential impact. We use a multi-pronged approach, drawing from various methods (observational/computational) and techniques (spectroscopy/photometry from multiple instruments), and bringing the data together to perform a rapid and robust threat assessment.} The visible reflectance spectrum of 2023~DZ$_{2}$ is consistent with that of an X-type asteroid. Light curves of this object obtained on two different nights give a rotation period $P$=6.2743$\pm$0.0005 min with an amplitude $A$=0.57$\pm$0.14~mag. We confirm that although its MOID is among the smallest known, 2023~DZ$_{2}$ will not impact Earth in the foreseeable future as a result of secular near-resonant behaviour. Our investigation shows that coordinated observation and interpretation of disparate data provides a robust approach from discovery to threat assessment when a virtual impactor is identified. We prove that critical information can be obtained within a few days after the announcement of the potential impactor., Comment: Accepted for publication in Astronomy and Astrophysics, 15 pages

Published
2023
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212. Combinatorial study of morsifications of real univariate singularities

Author

Bodin, Arnaud, Barroso, Evelia Rosa García, Popescu-Pampu, Patrick, and Sorea, Miruna-Stefana

Subjects
Mathematics - Algebraic Geometry, Mathematics - Combinatorics, 26C05, 05E14, 58K05, 14P25
Abstract

We study a broad class of morsifications of germs of univariate real analytic functions. We characterize the combinatorial types of the resulting Morse functions, via planar contact trees constructed from Newton-Puiseux roots of the polar curves of the morsifications., Comment: 23 pages, 16 figures. Compared to the first version, we clarified some statements as well as Figure 1 and we added Example 6.4 and Remarks 6.8, 7.1. To appear in Mathematische Nachrichten

Published
2023

213. Assessing the Importance of Frequency versus Compositionality for Subword-based Tokenization in NMT

Author

Wolleb, Benoist, Silvestri, Romain, Vernikos, Giorgos, Dolamic, Ljiljana, and Popescu-Belis, Andrei

Subjects
Computer Science - Computation and Language
Abstract

Subword tokenization is the de facto standard for tokenization in neural language models and machine translation systems. Three advantages are frequently cited in favor of subwords: shorter encoding of frequent tokens, compositionality of subwords, and ability to deal with unknown words. As their relative importance is not entirely clear yet, we propose a tokenization approach that enables us to separate frequency (the first advantage) from compositionality. The approach uses Huffman coding to tokenize words, by order of frequency, using a fixed amount of symbols. Experiments with CS-DE, EN-FR and EN-DE NMT show that frequency alone accounts for 90%-95% of the scores reached by BPE, hence compositionality has less importance than previously thought., Comment: Accepted at EAMT 2023

Published
2023

214. Toward accurate thermal modeling of phase change material based photonic devices

Author

Aryana, Kiumars, Kim, Hyun Jung, Popescu, Cosmin-Constantin, Vitale, Steven, Bae, Hyung Bin, Lee, Taewoo, Gu, Tian, and Hu, Juejun

Subjects
Physics - Optics, Physics - Applied Physics
Abstract

Reconfigurable or programmable photonic devices are rapidly growing and have become an integral part of many optical systems. The ability to selectively modulate electromagnetic waves through electrical stimuli is crucial in the advancement of a variety of applications from data communication and computing devices to environmental science and space explorations. Chalcogenide-based phase change materials (PCMs) are one of the most promising material candidates for reconfigurable photonics due to their large optical contrast between their different solid-state structural phases. Although significant efforts have been devoted to accurate simulation of PCM-based devices, in this paper, we highlight three important aspects which have often evaded prior models yet having significant impacts on the thermal and phase transition behavior of these devices: the enthalpy of fusion, the heat capacity change upon glass transition, as well as the thermal conductivity of liquid-phase PCMs. We further investigated the important topic of switching energy scaling in PCM devices, which also helps explain why the three above-mentioned effects have long been overlooked in electronic PCM memories but only become important in photonics. Our findings offer insight to facilitate accurate modeling of PCM-based photonic devices and can inform the development of more efficient reconfigurable optics.

Published
2023
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215. Pressure-Induced Phase Transition Versus Amorphization in Hybrid Methylammonium Lead Bromide Perovskite

Author

Liang, Akun, Turnbull, Robin, Popescu, Catalin, Fernandez-Guillen, Ismael, Abargues, Rafael, Boix, Pablo P., and Errandonea, Daniel

Subjects
Condensed Matter - Materials Science, Physics - Applied Physics
Abstract

The crystal structure of CH3NH3PbBr3 perovskite has been investigated under high-pressure by synchrotron-based powder X-ray diffraction. We found that after the previously reported phase transitions in CH3NH3PbBr3 (Pm-3m->Im-3->Pmn21), which occur below 2 GPa, there is a third transition to a crystalline phase at 4.6 GPa. This transition is reported here for the first time contradicting previous studies which reported amorphization of CH3NH3PbBr3 between 2.3 and 4.6 GPa. Our X-ray diffraction measurements show that CH3NH3PbBr3 remains crystalline up to 7.6 GPa, the highest pressure covered by experiments. The new high-pressure phase is also described by the space group Pmn21, but the transition involves abrupt changes in the unit-cell parameters and a 3% decrease of the unit-cell volume. Our conclusions are confirmed by optical-absorption experiments and visual observations and by the fact that changes induced by pressure up to 10 GPa are reversible. The optical studies also allow for the determination of the pressure dependence of the band-gap energy which is discussed using the structural information obtained from X-ray diffraction., Comment: 15 pages, 4 figures

Published
2023
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216. Structural, Vibrational, and Electronic Behavior of Two GaGeTe Polymorphs under compression

Author

Bandiello, Enrico, Gallego-Parra, Samuel, Liang, Akun, Sans, Juan Ángel, Cuenca-Gotor, Vanesa, da Silva, Estelina Lora, Vilaplana, Rosario, Rodríguez-Hernández, Plácida., Muñoz, Alfonso, Diaz-Anichtchenko, Daniel, Popescu, Catalin, Alabarse, Frederico Gil, Rudamas, Carlos, Drašar, Čestmír, Segura, Alfredo, Errandonea, Daniel, and Manjón, Francisco Javier

Subjects
Condensed Matter - Materials Science
Abstract

GaGeTe is a layered topological semimetal that has been recently found to exist in at least two different polytypes, $\alpha$-GaGeTe ($R\bar{3}m$) and $\beta$-GaGeTe ($P6_3 mc$). Here we report a joint experimental and theoretical study of the structural, vibrational, and electronic properties of these two polytypes at high pressure. Both polytypes show anisotropic compressibility and two phase transitions, above 7 and 15 GPa, respectively, as confirmed by XRD and Raman spectroscopy measurements. Although the nature of the high-pressure phases is not confirmed, comparison with other chalcogenides and total-energy calculations allow us to propose possible high-pressure phases for both polytypes with an increase in coordination for Ga and Ge atoms from 4 to 6. In particular, the simplification of the X-ray patterns for both polytypes above 15 GPa suggests a transition to a structure of relatively higher symmetry than the original one. This result is consistent with the rocksalt-like high-pressure phases observed in parent III-VI semiconductors, such as GaTe, GaSe, and InSe. Pressure-induced amorphization is observed upon pressure release. The electronic band structures of $\alpha$-GaGeTe and $\beta$-GaGeTe and their pressure dependence also show similarities to III-VI semiconductors, thus suggesting that the germanene-like sublayer induces a semimetallic character in both GaGeTe polytypes. Above 3 GPa, both polytypes lose their topological features, due to the opening of the direct band gap, while the reduction of the interlayer space increases the thermal conductivity at high pressure., Comment: Main manuscript: 47 pages, 12 figures, 4 tables; ESI: 20 pages, 12 figures, 9 tables

Published
2023

217. Mitigating IoT Botnet DDos Attacks through MUD and eBPF based Traffic Filtering

Author

Feraudo, Angelo, Popescu, Diana Andreea, Yadav, Poonam, Mortier, Richard, and Bellavista, Paolo

Subjects
Computer Science - Networking and Internet Architecture, Computer Science - Cryptography and Security
Abstract

As the prevalence of Internet-of-Things (IoT) devices becomes more and more dominant, so too do the associated management and security challenges. One such challenge is the exploitation of vulnerable devices for recruitment into botnets, which can be used to carry out Distributed Denial-of-Service (DDoS) attacks. The recent Manufacturer Usage Description (MUD) standard has been proposed as a way to mitigate this problem, by allowing manufacturers to define communication patterns that are permitted for their IoT devices, with enforcement at the gateway home router. In this paper, we present a novel integrated system implementation that uses a MUD manager (osMUD) to parse an extended set of MUD rules, which also allow for rate-limiting of traffic and for setting appropriate thresholds. Additionally, we present two new backends for MUD rule enforcement, one based on eBPF and the other based on the Linux standard iptables. The reported evaluation results show that these techniques are feasible and effective in protecting against attacks and in terms of their impact on legitimate traffic and on the home gateway., Comment: 12 pages, 10 figures, in review currently

Published
2023

219. Algebraic valuation ring extensions as limits of complete intersection algebras

Author

Popescu, Dorin

Subjects
Mathematics - Commutative Algebra, Mathematics - Algebraic Geometry
Abstract

We show that an algebraic immediate valuation ring extension of characteristic $p>0$ is a filtered union of complete intersection algebras of finite type., Comment: This is mainly Section 1 of arxiv:2004.11004 and it will appear in this form in Revista Matematica Complutense. arXiv admin note: text overlap with arXiv:2206.00472

Published
2023

220. Approximation and interpolation of deep neural networks

Author

Constantinescu, Vlad-Raul and Popescu, Ionel

Subjects
Computer Science - Machine Learning, Mathematics - Optimization and Control, Mathematics - Probability, Statistics - Machine Learning
Abstract

In this paper, we prove that in the overparametrized regime, deep neural network provide universal approximations and can interpolate any data set, as long as the activation function is locally in $L^1(\RR)$ and not an affine function. Additionally, if the activation function is smooth and such an interpolation networks exists, then the set of parameters which interpolate forms a manifold. Furthermore, we give a characterization of the Hessian of the loss function evaluated at the interpolation points. In the last section, we provide a practical probabilistic method of finding such a point under general conditions on the activation function., Comment: This is a revised, improved and more general result than the previous version

Published
2023

221. HighTEA: High energy Theory Event Analyser

Author

Czakon, Michał, Kassabov, Zahari, Mitov, Alexander, Poncelet, Rene, and Popescu, Andrei

Subjects
High Energy Physics - Phenomenology, High Energy Physics - Experiment
Abstract

We introduce HighTEA, a new paradigm for deploying fully-differential next-to-next-to leading order (NNLO) calculations for collider observables. In principle, any infrared safe observable can be computed and, with very few restrictions, the user has complete freedom in defining their calculation's setup. For example, one can compute generic n-dimensional distributions, can define kinematic variables and factorization/renormalization scales, and can modify the strong coupling and parton distributions. HighTEA operates on the principle of analyzing precomputed events. It has all the required hardware and software infrastructure such that users only need to request their calculation via the internet before receiving the results, typically within minutes, in the form of a histogram. No specialized knowledge or computing infrastructure is required to fully utilize HighTEA, which could be used by both experts in particle physics and the general public. The current focus is on all classes of LHC processes. Extensions beyond NNLO, or to $e^+e^-$ colliders, are natural next steps., Comment: 15 pages. HighTEA access and additional information: https://www.precision.hep.phy.cam.ac.uk/hightea/

Published
2023

222. Roles and Abilities of Academic and Research Librarians in Optimizing Access to Information: An Interpretative Analysis from the Romanian Librarians’ and Users’ Perspective

Author

Popescu Elena and Madge Octavia-Luciana

Subjects
quality management, knowledge management, academic libraries, special research libraries, skills of librarians, Bibliography. Library science. Information resources
Abstract

This study addresses the role of Romanian academic and research librarians in optimizing access to information in the digital age, in relation to quality management and knowledge management. The novelty of this study consists in its parallel analysis of both librarians’ and users’ perspectives on librarians’ roles and abilities in optimizing access to information. The results obtained by means of interpretative qualitative analysis combined with descriptive quantitative analysis revealed that Romanian librarians succeed in providing good information services, however, the demands and expectations of users highlight a continuous need for integration of librarians into the mission of the universities and research institutes, and knowledge sharing and a series of innovations are recommended. The results obtained by interpretative analysis, combined with quantitative analysis for corroboration, point to four interrelated themes regarding the Romanian librarians’ roles and abilities in optimizing access to information. The first principal idea is that librarians’ abilities and competencies are key assets for Romanian academic and special research libraries. The second is that Romanian librarians need training in knowledge management and quality management. The third is that embedded librarianship and knowledge sharing could add quality to libraries services. Finally, the fourth is that competency management can determine engagement of Romanian librarians in improving access to information.

Published
2024
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223. Twisted Troubles: A Rare Case of Intestinal Obstruction Due to Endometriosis and a Review of the Literature

Author

Ionut Eduard Iordache, Luana Alexandrescu, Alina Doina Nicoara, Razvan Popescu, Nicoleta Leopa, Gabriela Baltatescu, Andreea Nelson Twakor, Ionut Tiberiu Tofolean, and Liliana Steriu

Subjects
endometriosis, intestinal occlusion, volvulus, ileo-caecal anastomosis, extragenital, Medicine (General), R5-920
Abstract

Background and Objectives: Intestinal endometriosis is an exceptionally rare cause of intestinal obstruction. This case report and literature review aim to highlight the clinical presentation, diagnostic challenges, and surgical management of this condition. Materials and methods: We report the case of a 50-year-old female patient who presented diffuse abdominal pain, nausea, vomiting, a distended abdomen, and an absence of intestinal transit for gas and faeces. Initial symptoms included flatulence and constipation, which gradually worsened for two months prior to the patient’s hospital admission, leading to acute intestinal obstruction. Diagnostic investigations, including blood tests, ultrasound (USG), X-ray, and a contrast-enhanced computer tomography (CT) scan, revealed significant small bowel dilatation and an ileal volvulus. The patient underwent urgent hydro-electrolytic and metabolic rebalancing followed by a median laparotomy surgical procedure. Intraoperative findings included a distended small intestine and an obstructive ileal volvulus, and required an 8 cm segmental enterectomy and terminal ileostomy. Results: Postoperative recovery was slow but favourable, with a gradual digestive tolerance. Histopathological examination of the resected ileum revealed intestinal endometriosis characterized by a fibro-conjunctive reaction and nonspecific chronic active inflammation. Five months later, the patient underwent a successful reversal of the ileostomy with a mechanical lateral anastomosis of the cecum and ileum, resulting in a favourable postoperative course. Conclusions: This case underscores the importance of considering intestinal endometriosis in women presenting with unexplained gastrointestinal symptoms and highlights the need for timely surgical intervention and careful postoperative management. Further research is required to better understand the pathophysiology and optimal treatment strategies for intestinal endometriosis.

Published
2024
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224. Transforming outer space transportation through immersive technologies: a SWOT analysis

Author

Ulpia-Elena BOTEZATU, Alexandru STANCIU, Ella-Magdalena CIUPERCĂ, Sorin TOPOR, and Sabin POPESCU

Subjects
immersive technologies, virtual reality (vr), augmented reality (ar), mixed reality (mr), swot analysis, Automation, T59.5, Information technology, T58.5-58.64
Abstract

This study provides a SWOT analysis of immersive technologies, specifically Virtual Reality (VR), Augmented Reality (AR), and Mixed Reality (MR), in relation to space transportation. Immersive technologies have completely transformed astronaut training, spacecraft design, and public involvement in space. They provide notable benefits such expanded simulation capabilities, cost-effective training, and improved safety and efficiency. Notwithstanding these advantages, obstacles such as substantial implementation expenses, technological constraints, and user opposition persist. The study highlights favorable prospects for innovation and global cooperation, while also acknowledging possible hazards such as cybersecurity vulnerabilities, information saturation, and the swift obsolescence of technology. Organizations involved in outer space affairs may improve mission effectiveness and safety by strategically utilizing the strengths and potential of immersive technology, while also addressing their shortcomings and risks. This will promote further progress in space exploration. This research highlights the crucial significance of immersive technology in determining the future of space exploration.

Published
2024
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225. Search for a resonance decaying to a W boson and a photon in proton-proton collisions at s $$ \sqrt{s} $$ = 13 TeV using leptonic W boson decays

Author

The CMS collaboration, A. Hayrapetyan, A. Tumasyan, W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, K. Damanakis, M. Dragicevic, P. S. Hussain, M. Jeitler, N. Krammer, A. Li, D. Liko, I. Mikulec, J. Schieck, R. Schöfbeck, D. Schwarz, M. Sonawane, S. Templ, W. Waltenberger, C.-E. Wulz, T. Janssen, T. Van Laer, P. Van Mechelen, N. Breugelmans, J. D’Hondt, S. Dansana, A. De Moor, M. Delcourt, F. Heyen, S. Lowette, I. Makarenko, D. Müller, S. Tavernier, M. Tytgat, G. P. Van Onsem, S. Van Putte, D. Vannerom, B. Bilin, B. Clerbaux, A. K. Das, G. De Lentdecker, H. Evard, L. Favart, P. Gianneios, J. Jaramillo, A. Khalilzadeh, F. A. Khan, K. Lee, M. Mahdavikhorrami, A. Malara, S. Paredes, M. A. Shahzad, L. Thomas, M. Vanden Bemden, C. Vander Velde, P. Vanlaer, M. De Coen, D. Dobur, G. Gokbulut, Y. Hong, J. Knolle, L. Lambrecht, D. Marckx, K. Mota Amarilo, A. Samalan, K. Skovpen, N. Van Den Bossche, J. van der Linden, L. Wezenbeek, A. Benecke, A. Bethani, G. Bruno, C. Caputo, J. De Favereau De Jeneret, C. Delaere, I. S. Donertas, A. Giammanco, A. O. Guzel, Sa. Jain, V. Lemaitre, J. Lidrych, P. Mastrapasqua, T. T. Tran, S. Wertz, G. A. Alves, M. Alves Gallo Pereira, E. Coelho, G. Correia Silva, C. Hensel, T. Menezes De Oliveira, C. Mora Herrera, A. Moraes, P. Rebello Teles, M. Soeiro, A. Vilela Pereira, W. L. Aldá Júnior, M. Barroso Ferreira Filho, H. Brandao Malbouisson, W. Carvalho, J. Chinellato, E. M. Da Costa, G. G. Da Silveira, D. De Jesus Damiao, S. Fonseca De Souza, R. Gomes De Souza, M. Macedo, J. Martins, L. Mundim, H. Nogima, J. P. Pinheiro, A. Santoro, A. Sznajder, M. Thiel, C. A. Bernardes, L. Calligaris, T. R. Fernandez Perez Tomei, E. M. Gregores, B. Lopes Da Costa, I. Maietto Silverio, P. G. Mercadante, S. F. Novaes, B. Orzari, Sandra S. Padula, A. Aleksandrov, G. Antchev, R. Hadjiiska, P. Iaydjiev, M. Misheva, M. Shopova, G. Sultanov, A. Dimitrov, L. Litov, B. Pavlov, P. Petkov, A. Petrov, E. Shumka, S. Keshri, D. Laroze, S. Thakur, T. Cheng, T. Javaid, L. Yuan, Z. Hu, Z. Liang, J. Liu, K. Yi, G. M. Chen, H. S. Chen, M. Chen, F. Iemmi, C. H. Jiang, A. Kapoor, H. Liao, Z.-A. Liu, R. Sharma, J. N. Song, J. Tao, C. Wang, J. Wang, Z. Wang, H. Zhang, J. Zhao, A. Agapitos, Y. Ban, S. Deng, B. Guo, C. Jiang, A. Levin, C. Li, Q. Li, Y. Mao, S. Qian, S. J. Qian, X. Qin, X. Sun, D. Wang, H. Yang, L. Zhang, Y. Zhao, C. Zhou, S. Yang, Z. You, K. Jaffel, N. Lu, G. Bauer, B. Li, J. Zhang, X. Gao, Y. Li, Z. Lin, C. Lu, M. Xiao, C. Avila, D. A. Barbosa Trujillo, A. Cabrera, C. Florez, J. Fraga, J. A. Reyes Vega, F. Ramirez, C. Rendón, M. Rodriguez, A. A. Ruales Barbosa, J. D. Ruiz Alvarez, D. Giljanovic, N. Godinovic, D. Lelas, A. Sculac, M. Kovac, A. Petkovic, T. Sculac, P. Bargassa, V. Brigljevic, B. K. Chitroda, D. Ferencek, K. Jakovcic, S. Mishra, A. Starodumov, T. Susa, A. Attikis, K. Christoforou, A. Hadjiagapiou, C. Leonidou, J. Mousa, C. Nicolaou, L. Paizanos, F. Ptochos, P. A. Razis, H. Rykaczewski, H. Saka, A. 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Senger, E. Shokr, F. Stäger, R. Tramontano, C. Adloff, D. Bhowmik, C. M. Kuo, W. Lin, P. K. Rout, P. C. Tiwari, S. S. Yu, L. Ceard, K. F. Chen, P. s. Chen, Z. g. Chen, A. De Iorio, W.-S. Hou, T. h. Hsu, Y. w. Kao, S. Karmakar, G. Kole, Y. y. Li, R.-S. Lu, E. Paganis, X. f. Su, J. Thomas-Wilsker, L. s. Tsai, D. Tsionou, H. y. Wu, E. Yazgan, C. Asawatangtrakuldee, N. Srimanobhas, V. Wachirapusitanand, D. Agyel, F. Boran, F. Dolek, I. Dumanoglu, E. Eskut, Y. Guler, E. Gurpinar Guler, C. Isik, O. Kara, A. Kayis Topaksu, U. Kiminsu, G. Onengut, K. Ozdemir, A. Polatoz, B. Tali, U. G. Tok, S. Turkcapar, E. Uslan, I. S. Zorbakir, G. Sokmen, M. Yalvac, B. Akgun, I. O. Atakisi, E. Gülmez, M. Kaya, O. Kaya, S. Tekten, A. Cakir, K. Cankocak, G. G. Dincer, Y. Komurcu, S. Sen, O. Aydilek, B. Hacisahinoglu, I. Hos, B. Kaynak, S. Ozkorucuklu, O. Potok, H. Sert, C. Simsek, C. Zorbilmez, S. Cerci, B. Isildak, D. Sunar Cerci, T. Yetkin, A. Boyaryntsev, B. Grynyov, L. Levchuk, D. Anthony, J. J. Brooke, A. Bundock, F. Bury, E. Clement, D. Cussans, H. Flacher, M. Glowacki, J. Goldstein, H. F. Heath, M.-L. Holmberg, L. Kreczko, S. Paramesvaran, L. Robertshaw, S. Seif El Nasr-Storey, V. J. Smith, N. Stylianou, K. Walkingshaw Pass, A. H. Ball, K. W. Bell, A. Belyaev, C. Brew, R. M. Brown, D. J. A. Cockerill, C. Cooke, A. Elliot, K. V. Ellis, K. Harder, S. Harper, J. Linacre, K. Manolopoulos, D. M. Newbold, E. Olaiya, D. Petyt, T. Reis, A. R. Sahasransu, G. Salvi, T. Schuh, C. H. Shepherd-Themistocleous, I. R. Tomalin, K. C. Whalen, T. Williams, I. Andreou, R. Bainbridge, P. Bloch, C. E. Brown, O. Buchmuller, V. Cacchio, C. A. Carrillo Montoya, G. S. Chahal, D. Colling, J. S. Dancu, I. Das, P. Dauncey, G. Davies, J. Davies, M. Della Negra, S. Fayer, G. Fedi, G. Hall, M. H. Hassanshahi, A. Howard, G. Iles, C. R. Knight, J. Langford, J. León Holgado, L. Lyons, A.-M. Magnan, S. Mallios, M. Mieskolainen, J. Nash, M. Pesaresi, P. B. Pradeep, B. C. Radburn-Smith, A. Richards, A. 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Sagir, X. Shen, F. Simpson, M. Stamenkovic, N. Venkatasubramanian, X. Yan, S. Abbott, C. Brainerd, R. Breedon, H. Cai, M. Calderon De La Barca Sanchez, M. Chertok, M. Citron, J. Conway, P. T. Cox, R. Erbacher, F. Jensen, O. Kukral, G. Mocellin, M. Mulhearn, S. Ostrom, W. Wei, S. Yoo, F. Zhang, M. Bachtis, R. Cousins, A. Datta, G. Flores Avila, J. Hauser, M. Ignatenko, M. A. Iqbal, T. Lam, E. Manca, A. Nunez Del Prado, D. Saltzberg, V. Valuev, R. Clare, J. W. Gary, M. Gordon, G. Hanson, W. Si, A. Aportela, A. Arora, J. G. Branson, S. Cittolin, S. Cooperstein, D. Diaz, J. Duarte, L. Giannini, Y. Gu, J. Guiang, R. Kansal, V. Krutelyov, R. Lee, J. Letts, M. Masciovecchio, F. Mokhtar, M. Pieri, M. Quinnan, B. V. Sathia Narayanan, V. Sharma, M. Tadel, E. Vourliotis, F. Würthwein, Y. Xiang, A. Yagil, A. Barzdukas, L. Brennan, C. Campagnari, K. Downham, C. Grieco, J. Incandela, A. J. Li, P. Masterson, H. Mei, J. Richman, S. N. Santpur, U. Sarica, R. Schmitz, F. Setti, J. Sheplock, D. Stuart, T. Á. Vámi, S. Wang, D. Zhang, A. Bornheim, O. Cerri, A. Latorre, J. Mao, H. B. Newman, G. Reales Gutiérrez, M. Spiropulu, J. R. Vlimant, S. Xie, R. Y. Zhu, J. Alison, S. An, P. Bryant, M. Cremonesi, V. Dutta, T. Ferguson, T. A. Gómez Espinosa, A. Harilal, A. Kallil Tharayil, C. Liu, T. Mudholkar, S. Murthy, P. Palit, K. Park, M. Paulini, A. Roberts, A. Sanchez, W. Terrill, J. P. Cumalat, W. T. Ford, A. Hart, A. Hassani, G. Karathanasis, N. Manganelli, J. Pearkes, C. Savard, N. Schonbeck, K. Stenson, K. A. Ulmer, S. R. Wagner, N. Zipper, D. Zuolo, J. Alexander, S. Bright-Thonney, X. Chen, D. J. Cranshaw, J. Fan, X. Fan, S. Hogan, P. Kotamnives, J. Monroy, M. Oshiro, J. R. Patterson, M. Reid, A. Ryd, J. Thom, P. Wittich, R. Zou, M. Albrow, M. Alyari, O. Amram, G. Apollinari, A. Apresyan, L. A. T. Bauerdick, D. Berry, J. Berryhill, P. C. Bhat, K. Burkett, J. N. Butler, A. Canepa, G. B. Cerati, H. W. K. Cheung, F. Chlebana, G. Cummings, J. Dickinson, I. Dutta, V. D. Elvira, Y. Feng, J. Freeman, A. Gandrakota, Z. Gecse, L. Gray, D. Green, A. Grummer, S. Grünendahl, D. Guerrero, O. Gutsche, R. M. Harris, R. Heller, T. C. Herwig, J. Hirschauer, B. Jayatilaka, S. Jindariani, M. Johnson, U. Joshi, T. Klijnsma, B. Klima, K. H. M. Kwok, S. Lammel, D. Lincoln, R. Lipton, T. Liu, C. Madrid, K. Maeshima, C. Mantilla, D. Mason, P. McBride, P. Merkel, S. Mrenna, S. Nahn, J. Ngadiuba, D. Noonan, S. Norberg, V. Papadimitriou, N. Pastika, K. Pedro, C. Pena, F. Ravera, A. Reinsvold Hall, L. Ristori, M. Safdari, E. Sexton-Kennedy, N. Smith, A. Soha, L. Spiegel, S. Stoynev, J. Strait, L. Taylor, S. Tkaczyk, N. V. Tran, L. Uplegger, E. W. Vaandering, I. Zoi, C. Aruta, P. Avery, D. Bourilkov, P. Chang, V. Cherepanov, R. D. Field, E. Koenig, M. Kolosova, J. Konigsberg, A. Korytov, K. Matchev, N. Menendez, G. Mitselmakher, K. Mohrman, A. Muthirakalayil Madhu, N. Rawal, S. Rosenzweig, Y. Takahashi, T. Adams, A. Al Kadhim, A. Askew, S. Bower, V. Hagopian, R. Hashmi, R. S. Kim, T. Kolberg, G. Martinez, H. Prosper, P. R. Prova, M. Wulansatiti, R. Yohay, B. Alsufyani, M. M. Baarmand, S. Butalla, S. Das, T. Elkafrawy, M. Hohlmann, E. Yanes, M. R. Adams, A. Baty, C. Bennett, R. Cavanaugh, R. Escobar Franco, O. Evdokimov, C. E. Gerber, M. Hawksworth, A. Hingrajiya, D. J. Hofman, J. h. Lee, D. S. Lemos, A. H. Merrit, C. Mills, S. Nanda, G. Oh, B. Ozek, D. Pilipovic, R. Pradhan, E. Prifti, T. Roy, S. Rudrabhatla, M. B. Tonjes, N. Varelas, M. A. Wadud, Z. Ye, M. Alhusseini, D. Blend, K. Dilsiz, L. Emediato, G. Karaman, O. K. Köseyan, J.-P. Merlo, A. Mestvirishvili, O. Neogi, H. Ogul, Y. Onel, A. Penzo, C. Snyder, E. Tiras, B. Blumenfeld, L. Corcodilos, J. Davis, A. V. Gritsan, L. Kang, S. Kyriacou, P. Maksimovic, M. Roguljic, J. Roskes, S. Sekhar, M. Swartz, A. Abreu, L. F. Alcerro Alcerro, J. Anguiano, S. Arteaga Escatel, P. Baringer, A. Bean, Z. Flowers, D. Grove, J. King, G. Krintiras, M. Lazarovits, C. Le Mahieu, J. Marquez, M. Murray, M. Nickel, M. Pitt, S. Popescu, C. Rogan, C. Royon, R. Salvatico, S. Sanders, C. Smith, G. Wilson, B. Allmond, R. Gujju Gurunadha, A. Ivanov, K. Kaadze, Y. Maravin, J. Natoli, D. Roy, G. Sorrentino, A. Baden, A. Belloni, J. Bistany-riebman, Y. M. Chen, S. C. Eno, N. J. Hadley, S. Jabeen, R. G. Kellogg, T. Koeth, B. Kronheim, Y. Lai, S. Lascio, A. C. Mignerey, S. Nabili, C. Palmer, C. Papageorgakis, M. M. Paranjpe, E. Popova, A. Shevelev, L. Wang, J. Bendavid, I. A. Cali, P. c. Chou, M. D’Alfonso, J. Eysermans, C. Freer, G. Gomez-Ceballos, M. Goncharov, G. Grosso, P. Harris, D. Hoang, D. Kovalskyi, J. Krupa, L. Lavezzo, Y.-J. Lee, K. Long, C. Mcginn, A. Novak, C. Paus, C. Roland, G. Roland, S. Rothman, G. S. F. Stephans, B. Wyslouch, T. J. Yang, B. Crossman, B. M. Joshi, C. Kapsiak, M. Krohn, D. Mahon, J. Mans, B. Marzocchi, M. Revering, R. Rusack, R. Saradhy, N. Strobbe, K. Bloom, D. R. Claes, G. Haza, J. Hossain, C. Joo, I. Kravchenko, J. E. Siado, W. Tabb, A. Vagnerini, A. Wightman, F. Yan, D. Yu, H. Bandyopadhyay, L. Hay, H. w. Hsia, I. Iashvili, A. Kalogeropoulos, A. Kharchilava, M. Morris, D. Nguyen, J. Pekkanen, S. Rappoccio, H. Rejeb Sfar, A. Williams, P. Young, G. Alverson, E. Barberis, J. Bonilla, J. Dervan, Y. Haddad, Y. Han, A. Krishna, J. Li, M. Lu, G. Madigan, R. Mccarthy, D. M. Morse, V. Nguyen, T. Orimoto, A. Parker, L. Skinnari, D. Wood, J. Bueghly, S. Dittmer, K. A. Hahn, Y. Liu, Y. Miao, D. G. Monk, M. H. Schmitt, A. Taliercio, M. Velasco, G. Agarwal, R. Band, R. Bucci, S. Castells, A. Das, R. Goldouzian, M. Hildreth, K. W. Ho, K. Hurtado Anampa, T. Ivanov, C. Jessop, K. Lannon, J. Lawrence, N. Loukas, L. Lutton, J. Mariano, N. Marinelli, I. Mcalister, T. McCauley, C. Mcgrady, C. Moore, Y. Musienko, H. Nelson, M. Osherson, A. Piccinelli, R. Ruchti, A. Townsend, Y. Wan, M. Wayne, H. Yockey, M. Zarucki, L. Zygala, A. Basnet, B. Bylsma, M. Carrigan, L. S. Durkin, C. Hill, M. Joyce, M. Nunez Ornelas, K. Wei, B. L. Winer, B. R. Yates, H. Bouchamaoui, P. Das, G. Dezoort, P. Elmer, A. Frankenthal, B. Greenberg, N. Haubrich, K. Kennedy, G. Kopp, S. Kwan, D. Lange, A. Loeliger, D. Marlow, I. Ojalvo, J. Olsen, D. Stickland, C. Tully, S. Malik, A. S. Bakshi, S. Chandra, R. Chawla, A. Gu, L. Gutay, M. Jones, A. W. Jung, A. M. Koshy, M. Liu, G. Negro, N. Neumeister, G. Paspalaki, S. Piperov, V. Scheurer, J. F. Schulte, M. Stojanovic, J. Thieman, A. K. Virdi, F. Wang, A. Wildridge, W. Xie, Y. Yao, J. Dolen, N. Parashar, A. Pathak, D. Acosta, T. Carnahan, K. M. Ecklund, P. J. Fernández Manteca, S. Freed, P. Gardner, F. J. M. Geurts, I. Krommydas, W. Li, J. Lin, O. Miguel Colin, B. P. Padley, R. Redjimi, J. Rotter, E. Yigitbasi, Y. Zhang, A. Bodek, P. de Barbaro, R. Demina, J. L. Dulemba, A. Garcia-Bellido, O. Hindrichs, A. Khukhunaishvili, N. Parmar, P. Parygin, R. Taus, B. Chiarito, J. P. Chou, S. V. Clark, D. Gadkari, Y. Gershtein, E. Halkiadakis, M. Heindl, C. Houghton, D. Jaroslawski, S. Konstantinou, I. Laflotte, A. Lath, R. Montalvo, K. Nash, J. Reichert, H. Routray, P. Saha, S. Salur, S. Schnetzer, S. Somalwar, R. Stone, S. A. Thayil, S. Thomas, J. Vora, H. Wang, D. Ally, A. G. Delannoy, S. Fiorendi, S. Higginbotham, T. Holmes, A. R. Kanuganti, N. Karunarathna, L. Lee, E. Nibigira, S. Spanier, D. Aebi, M. Ahmad, T. Akhter, O. Bouhali, R. Eusebi, J. Gilmore, T. Huang, T. Kamon, S. Luo, R. Mueller, D. Overton, D. Rathjens, A. Safonov, N. Akchurin, J. Damgov, N. Gogate, V. Hegde, A. Hussain, Y. Kazhykarim, K. Lamichhane, A. Mankel, T. Peltola, I. Volobouev, E. Appelt, Y. Chen, S. Greene, A. Gurrola, W. Johns, R. Kunnawalkam Elayavalli, A. Melo, F. Romeo, P. Sheldon, S. Tuo, J. Velkovska, J. Viinikainen, B. Cardwell, H. Chung, B. Cox, J. Hakala, R. Hirosky, A. Ledovskoy, C. Neu, P. E. Karchin, A. Aravind, K. Black, T. Bose, S. Dasu, I. De Bruyn, P. Everaerts, C. Galloni, H. He, M. Herndon, A. Herve, C. K. Koraka, A. Lanaro, R. Loveless, J. Madhusudanan Sreekala, A. Mallampalli, A. Mohammadi, G. Parida, L. Pétré, D. Pinna, A. Savin, V. Shang, W. H. Smith, D. Teague, H. F. Tsoi, W. Vetens, A. Warden, S. Afanasiev, V. Alexakhin, V. Andreev, Yu. Andreev, T. Aushev, M. Azarkin, A. Babaev, V. Blinov, E. Boos, V. Borshch, D. Budkouski, V. Bunichev, V. Chekhovsky, R. Chistov, M. Danilov, A. Dermenev, T. Dimova, D. Druzhkin, M. Dubinin, L. Dudko, G. Gavrilov, V. Gavrilov, S. Gninenko, V. Golovtcov, N. Golubev, I. Golutvin, I. Gorbunov, A. Gribushin, Y. Ivanov, V. Kachanov, V. Karjavine, A. Karneyeu, V. Kim, M. Kirakosyan, D. Kirpichnikov, M. Kirsanov, V. Klyukhin, O. Kodolova, D. Konstantinov, V. Korenkov, A. Kozyrev, N. Krasnikov, A. Lanev, P. Levchenko, N. Lychkovskaya, V. Makarenko, A. Malakhov, V. Matveev, V. Murzin, A. Nikitenko, S. Obraztsov, V. Oreshkin, V. Palichik, V. Perelygin, M. Perfilov, S. Petrushanko, S. Polikarpov, V. Popov, O. Radchenko, M. Savina, V. Savrin, V. Shalaev, S. Shmatov, S. Shulha, Y. Skovpen, S. Slabospitskii, V. Smirnov, D. Sosnov, V. Sulimov, A. Terkulov, O. Teryaev, I. Tlisova, A. Toropin, L. Uvarov, A. Uzunian, A. Vorobyev, G. Vorotnikov, N. Voytishin, B. S. Yuldashev, A. Zarubin, I. Zhizhin, and A. Zhokin

Subjects
Beyond Standard Model, Hadron-Hadron Scattering, Particle and Resonance Production, Photon Production, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract A search for a new charged particle X with mass between 0.3 and 2.0 TeV decaying to a W boson and a photon is presented, using proton-proton collision data at a center-of-mass energy of 13 TeV, collected by the CMS experiment and corresponding to an integrated luminosity of 138 fb −1. Particle X has electric charge ±1 and is assumed to have spin 0. The search is performed using the electron and muon decays of the W boson. No significant excess above the predicted background is observed. The upper limit at 95% confidence level on the product of the production cross section of the X and its branching fraction to a W boson and a photon is found to be 94 (137) fb for a 0.3 TeV resonance and 0.75 (0.81) fb for a 2.0 TeV resonance, for an X width-to-mass ratio of 0.01% (5%). This search presents the most stringent constraints to date on the existence of such resonances across the probed mass range. A statistical combination with an earlier study based on the hadronic decay mode of the W boson is also performed, and the upper limit at 95% confidence level for a 2.0 TeV resonance is reduced to 0.50 (0.63) fb for an X width-to-mass ratio of 0.01% (5%).

Published
2024
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226. APPLICATIONS OF DIGITAL TECHNOLOGY IN DATA TRANSFER FROM THE DENTAL OFFICE TO THE DENTAL LAB

Author

Iulia-Roxana Marinescu, Horia Octavian Manolea, Alexandru Andrei Iliescu, Monica Scrieciu, Willi Uriciuc, and Adrian Marcel Popescu

Subjects
digital dentistry, optical impression, intraoral scan, dental laboratory, oral rehabilitation, Dentistry, RK1-715
Abstract

Nowadays, digital technologies represent an essential tool for dentists and dental technicians, and the backbone of the communication between them. Aim of the study is to analyze the application of digital technologies in a common dental office and in transferring information to the dental lab. Materials and methods. The retrospective study included patients who presented for treatment to the dentist, in a 12 months period of time. Searched databases included dental charts, radiologic and imagistic data (OPG, CBCT), clinical photos and digital dental impressions. A comparison was made between the used digital tools as frequency. Results: 580 patients were included, 275 men and 305 women, aged between 19 and 82. Digital technologies used in the dental office in the studied period were: OPG (100%), CBCT examinations (25,34%), digital photographic exams (38,10%), intraoral scanning (24,13%), digital intraoral impressions (19,65%). Conclusions: All patients who attended the dental office during the study period received an OPG examination, while significant fewer patients were investigated using other digital technologies. For an easier, faster and complete data transfer between dental office and dental lab, digital evaluation is mandatory.

Published
2024
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227. RELIABILITY OF FRANKFURT MANDIBULAR ANGLE MEASUREMENT ON PANORAMIC RADIOGRAPHIES CONSIDERING SOME PATIENT POSITION VARIATIONS

Author

Dragos Epistatu, Ruxandra Banu, Mălina Meilă, Mihaela Pantea, Ilinca A. Iancu, and Manuela Popescu

Subjects
frankfurt-mandibular plane angle, panoramic radiography, Dentistry, RK1-715
Abstract

Aim of the study: Dentists frequently recommend panoramic radiographs (PR). Facial divergence is an indicator of the growth pattern, in relation to bite force and possible evolution of the VDO (vertical dimension of occlusion) over time. Materials and methods: Our study compared the measurement of the Frankfurt-mandibular plane angle (FMA) on the panoramic x-rays with the angle value measured on the profile tele-radiographs (lateral cephalograms). We have considered possible positioning errors caused by different head tilts while taking the PR. Results: Radiographs taken in disocclusion increased the determined FMA value by approximately 2° (2.28°). Conclusions: Even with some acceptable patient’s head tiltings and small positional asymmetries, the FMA measurements on the panoramic radiographs could be considered reliable.

Published
2024
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228. Successful TAVI-in-TAVI for degenerated bioprosthetic aortic valve with severe stenosis-a case report

Author

Apostu Alexandra, Deleanu Dan, Parasca Cătălina, Capșa Răzvan, Dobrovie Monica, Popescu Bogdan Alexandru, Chioncel Ovidiu, Iliescu Vlad Anton, and Jurcuţ Ruxandra

Subjects
aortic stenosis, heart failure, transcatheter aortic valve implantation, valve-in-valve, stenoză aortică, insuficiență cardiacă, implantare de valvă aortică transcateter, valvă în valvă, Internal medicine, RC31-1245
Abstract

Aortic stenosis is one of the leading causes of valvular disease requiring surgery or transcatheter intervention, with a rising prevalence due to the aging population. Current guidelines recommend transcatheter aortic valve implantation (TAVI) as the first-line treatment for patients with symptomatic severe aortic stenosis and high surgical risk. The indications for TAVI have expanded to low-surgical-risk patients due to increased operator experience and improved implanted devices with a dramatic reduction of complications. Considering the limited durability of bioprostheses, TAVI-in-TAVI procedures have been successfully performed as an alternative to surgery.

Published
2024
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229. ASSESSING THE EFFECTS OF AN OCCLUSAL DISHARMONY ONTO THE DENTO-MAXILLARY SYSTEM USING THE FINITE ELEMENT METHOD

Author

Popa Diana Angelica, Mercuț Veronica, Popescu Adrian Marcel, Târtea Daniel Adrian, Castravete Ștefan, Rîcă Gabriel Radu, Scrieciu Monica, Amărăscu Marina Olimpia, and Vlăduțu Diana-Elena

Subjects
virtual model, dento-maxillary system, finite element method, Dentistry, RK1-715
Abstract

Aim of the study. To obtain two virtual models of dento-maxillary system with a detailed representation of the TMJ, in order to highlight through the finite element method the way in which the stresses are distributed on the components of the dento-maxillary system, when the dental occlusion is modified. Material and methods. To obtain the geometric data for the mandibular and maxillary structures, a CT scan of an open-mouthed skull was used, resulting in a series of 2D DICOM images. The transformation of these 2D DICOM images into a 3D format was performed using MIMICS software. The TMJ was reconstructed in the computer-aided design software based on established assumptions and reference data. Computational analysis of the mandibular structure involved discretizing its geometry into finite elements, a widely used numerical technique that divides complex structures into smaller, manageable elements for computational analysis. In this study, FEM was adopted to facilitate the simulation and evaluation of biomechanical responses in dento-maxillary system. Results. The base model served as a reference, depicting the structural response of the mandible to mouth closing forces without any additional intervention elements. The modified model by incorporating a 1 mm plate between the 1st lower molar and the antagonistic premolar induced a change in mandibular dynamics. Conclusions. The study allowed to obtain a virtual model of dento-maxillary system with faithful reproduction of the components of the TMJ and to evaluate the demands on the dental arches and the TMJ in the case of the basic model and the modified one. The inclusion of a premature contact at the level of one hemiarch led to the redistribution of pressure forces at the level of the dental arches and stress in the two TMJs.

Published
2024
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230. DIAGNOSIS OF THE VARIATION IN THE SIZE OF PERIAPICAL LESIONS BY USING CT BEFORE AND AFTER RADIOTHERAPY IN PATIENTS WITH ENT CANCER

Author

Cristina Antohi, Mihaela Salceanu, Tudor Hamburda, Roxana Popescu, Danisia Haba, and Anca Melian

Subjects
ct, ent cancer, periapical lesions, Dentistry, RK1-715
Abstract

Objectives: The aim of this study was to evaluate the variation in the size of periapical lesions in patients with ENT cancer before and after radiotherapy by using the imaging examination represented by CT. Materials and methods: our study included 35 cancer patients-34 men and one female, with ENT cancer, under treatment at the Regional Institute of Oncology, Iasi. They were examinated by four endodontist, two radiologists and an ENT doctor. We measured the size of the periapical lesions before and after radiotherapy. Results: We found the change in the dimensions of periapical lesions: their maximum overall size was initially 5.4591 ± 3.88509 mm; after radiotherapy the global maximum size reached 7.0000 ± 3.37510, reaching 14.00 mm. The observed difference was statistically significant, so it could be stated that radiotherapy accentuates the severity of periapical lesions systematically. Before radiotherapy, the most extensive periapical lesions were observed in the case of laryngeal neoplasm ( with an average of 6.6778 ± 4.17246 mm) and nasopharyngeal neoplasm ( with an average of 6.000 ± 2.82843 mm) and the lowest ones were found in the case of the neoplasm of the oropharynx (with an average of 4.0000 ± 3.74166 mm). After radiotherapy, we found an increase in the size of the periapical lesions in the case of all five types of neoplasm investigated. The most extensive lesions were observed in the case of the neoplasm of the oropharynx, with an average of 7.6000 ± 3.84708 mm, followed by the neoplasm of the larynx, with an average of 7.4000 ± 3.33999 and the neoplasm of the oral cavity, with an average of 7.4000 ± 4.33590 mm. Disscusions: In terms of expectancy and quality of life of patients can only be achieved through a multidisciplinary approach. As soon as the dentist diagnoses a pontetially malignant disorder in the ENT sphere, patients should undergo an ENT screening complete for detecting lesions in any area of the upper aerodigestive tract. After radiotherapy an increase in the size of the periapical lesions is observed. The ENT doctor must encourage the patients with ENT cancer to extract their teeth with periapical lesions before the implementation of radiotherapy to avoid the risk of postradiotherapy osteoradionecrosis. Conclusions: By using CT, the increase in the size of periapical lesions after radiotherapy is observed in patients with cancer in the ENT sphere.

Published
2024
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231. THE SIDE EFFECTS OF RADIOTHERAPY IN THE PATIENT WITH ENT CANCER

Author

Cristina Antohi, Danisia Haba, Alexandra Corina Concita, Roxana Popescu, Radu Eduard Cernei, and Mihaela Salceanu

Subjects
side effects, ct, ent cancer, dentist., Dentistry, RK1-715
Abstract

Objectives: Our aim was to demonstrate the occurrence of post-radiotherapy side effects- even in the case of using intensively modulated therapy (IMRT) in patients with ENT cancer as its are: radiomucositis, dental caries, osteoradionecrosis, the increase in the size of the existing periapical lesions before radiotherapy, dysphagia, dysgeusia. Materials and methods: Our study included 35 cancer patients age between 32-81 years old with ENT cancer- neoplasm of larynx, oropharynx, oral cavity, nasopharynx, hypopharynx, sinuses; under treatment at the Regional Institute of Oncology, Iasi. They were examinated by one dental generalist, two endodontist, one radiologist, one doctor specialized in radiotherapy and an ENT doctor before and after radiotherapy. We used as irradiation dose between 50-70 Gy. Results: All patients suffered from various forms of cancer; the majority (40%) presented a neoplasm of the larynx, 8 patients (22,9%) presented a neoplasm of oropharynx, 6 patients (17,1%) presented a neoplasm of the oral cavity. Other forms of neoplasm found were nasopharynx, hypopharynx and respectively sinus neoplasm (1 case). The vast majority of the patients presented radiomucositis grade 2 (34,3%) and 3 (45,7%). The distribution of the localization of periapical lesions changed before and after radiotherapy. Osteoradionecrosis was initially diagnosed in 3 of the 35 patients (8,6%); after radiotherapy osteoradionecrosis was diagnosed in 6 patients (17,1%). We did not identify a statistically significant relationship between the dose of radiation administered and the degree of radiomucositis. Disscusions: Our retrospective study reported a frequency of 40% cancer of the larynx, 22,9% cancer of the oropharynx and 17,1% neoplasm of the oral cavity, followed by cancer of the nasopharynx, hypopharynx and sinus neoplasm out of a total of 35 patients taken into account. Taking into account the fact that the patients received an irradiation dose between 70 Gy (65,7%)- 66 Gy (22,9%), the degree of radiomucositis was mainly 2 (34,3%) or 3 (45,7%). We observed an increase in the diameter of the periapical lesions after radiotherapy associated with the dose of radiation administered. Areas with osteoradionecrosis revealed the same tendency of increase in their comparative analysis after the applied irradiation doses. Conclusions: The management of the side effects of radiotherapy can be managed favorably for the oncological patient through a close collaboration between the general dentist, ENT and the radiotherapist.

Published
2024
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232. Infrared spectral profiling of demyelinating activity in multiple sclerosis brain tissue

Author

Oleksandr Gakh, Jordan M. Wilkins, Yong Guo, Bogdan F. Popescu, Stephen D. Weigand, Alicja Kalinowska-Lyszczarz, and Claudia F. Lucchinetti

Subjects
Biomolecular profiling, Cortex, Demyelinating activity, Human brain tissue, Fourier transform infrared spectroscopy, Lesions, Neurology. Diseases of the nervous system, RC346-429
Abstract

Abstract Multiple sclerosis (MS) is a leading cause of non-traumatic disability in young adults. The highly dynamic nature of MS lesions has made them difficult to study using traditional histopathology due to the specificity of current stains. This requires numerous stains to track and study demyelinating activity in MS. Thus, we utilized Fourier transform infrared (FTIR) spectroscopy to generate holistic biomolecular profiles of demyelinating activities in MS brain tissue. Multivariate analysis can differentiate MS tissue from controls. Analysis of the absorbance spectra shows profound reductions of lipids, proteins, and phosphate in white matter lesions. Changes in unsaturated lipids and lipid chain length indicate oxidative damage in MS brain tissue. Altered lipid and protein structures suggest changes in MS membrane structure and organization. Unique carbohydrate signatures are seen in MS tissue compared to controls, indicating altered metabolic activities. Cortical lesions had increased olefinic lipid content and abnormal membrane structure in normal appearing MS cortex compared to controls. Our results suggest that FTIR spectroscopy can further our understanding of lesion evolution and disease mechanisms in MS paving the way towards improved diagnosis, prognosis, and development of novel therapeutics.

Published
2024
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233. Effects of prosthesis-patient mismatch on cardiac function and clinical outcome after transcatheter aortic valve implantation

Author

Parasca Catalina A., Calin Andreea, Rosca Monica, Botezatu Simona, Enache Roxana, Beladan Carmen, Deleanu Dan, Chioncel Ovidiu, Bubenek-Turconi Serban, Iliescu Vlad A., and Popescu Bogdan A.

Subjects
aortic stenosis, tavi, prosthesis-patient mismatch, la function, prognosis, Internal medicine, RC31-1245
Abstract

Transcatheter aortic valve implantation (TAVI) prostheses have better hemodynamics compared to surgical prostheses, with a lower incidence of prosthesis-patient mismatch (PPM). Nonetheless, the effects of PPM have been controversial regarding clinical impact. This study aims to determine the short-term impact of PPM on cardiac function and the effect of PPM on mid-term outcome in patients undergoing transfemoral TAVI with balloon-expandable valves.

Published
2024
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234. Search for new physics in high-mass diphoton events from proton-proton collisions at s $$ \sqrt{\textrm{s}} $$ = 13 TeV

Author

The CMS collaboration, A. Hayrapetyan, A. Tumasyan, W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, K. Damanakis, M. Dragicevic, P. S. Hussain, M. Jeitler, N. Krammer, A. Li, D. Liko, I. Mikulec, J. Schieck, R. Schöfbeck, D. Schwarz, M. Sonawane, S. Templ, W. Waltenberger, C.-E. Wulz, M. R. Darwish, T. Janssen, T. Van Laer, P. Van Mechelen, N. Breugelmans, J. D’Hondt, S. Dansana, A. De Moor, M. Delcourt, F. Heyen, S. Lowette, I. Makarenko, D. Müller, S. Tavernier, M. Tytgat, G. P. Van Onsem, S. Van Putte, D. Vannerom, B. Bilin, B. Clerbaux, A. K. Das, G. De Lentdecker, H. Evard, L. Favart, P. Gianneios, J. Jaramillo, A. Khalilzadeh, F. A. Khan, K. Lee, M. Mahdavikhorrami, A. Malara, S. Paredes, M. A. Shahzad, L. Thomas, M. Vanden Bemden, C. Vander Velde, P. Vanlaer, M. De Coen, D. Dobur, G. Gokbulut, Y. Hong, J. Knolle, L. Lambrecht, D. Marckx, K. Mota Amarilo, A. Samalan, K. Skovpen, N. Van Den Bossche, J. van der Linden, L. Wezenbeek, A. Benecke, A. Bethani, G. Bruno, C. Caputo, J. De Favereau De Jeneret, C. Delaere, I. S. Donertas, A. Giammanco, A. O. Guzel, Sa. Jain, V. Lemaitre, J. Lidrych, P. Mastrapasqua, T. T. Tran, S. Wertz, G. A. Alves, M. Alves Gallo Pereira, E. Coelho, G. Correia Silva, C. Hensel, T. Menezes De Oliveira, A. Moraes, P. Rebello Teles, M. Soeiro, A. Vilela Pereira, W. L. Aldá Júnior, M. Barroso Ferreira Filho, H. Brandao Malbouisson, W. Carvalho, J. Chinellato, E. M. Da Costa, G. G. Da Silveira, D. De Jesus Damiao, S. Fonseca De Souza, R. Gomes De Souza, M. Macedo, J. Martins, C. Mora Herrera, L. Mundim, H. Nogima, J. P. Pinheiro, A. Santoro, A. Sznajder, M. Thiel, C. A. Bernardes, L. Calligaris, T. R. Fernandez Perez Tomei, E. M. Gregores, I. Maietto Silverio, P. G. Mercadante, S. F. Novaes, B. Orzari, Sandra S. Padula, A. Aleksandrov, G. Antchev, R. Hadjiiska, P. Iaydjiev, M. Misheva, M. Shopova, G. Sultanov, A. Dimitrov, L. Litov, B. Pavlov, P. Petkov, A. Petrov, E. Shumka, S. Keshri, S. Thakur, T. Cheng, T. Javaid, L. Yuan, Z. Hu, Z. Liang, J. Liu, K. Yi, G. M. Chen, H. S. Chen, M. Chen, F. Iemmi, C. H. Jiang, A. Kapoor, H. Liao, Z.-A. Liu, R. Sharma, J. N. Song, J. Tao, C. Wang, J. Wang, Z. Wang, H. Zhang, J. Zhao, A. Agapitos, Y. Ban, S. Deng, B. Guo, C. Jiang, A. Levin, C. Li, Q. Li, Y. Mao, S. Qian, S. J. Qian, X. Qin, X. Sun, D. Wang, H. Yang, L. Zhang, Y. Zhao, C. Zhou, S. Yang, Z. You, K. Jaffel, N. Lu, G. Bauer, B. Li, J. Zhang, X. Gao, Z. Lin, C. Lu, M. Xiao, C. Avila, D. A. Barbosa Trujillo, A. Cabrera, C. Florez, J. Fraga, J. A. Reyes Vega, F. Ramirez, C. Rendón, M. Rodriguez, A. A. Ruales Barbosa, J. D. Ruiz Alvarez, D. Giljanovic, N. Godinovic, D. Lelas, A. Sculac, M. Kovac, A. Petkovic, T. Sculac, P. Bargassa, V. Brigljevic, B. K. Chitroda, D. Ferencek, K. Jakovcic, S. Mishra, A. Starodumov, T. Susa, A. Attikis, K. Christoforou, A. Hadjiagapiou, C. Leonidou, J. Mousa, C. Nicolaou, L. Paizanos, F. Ptochos, P. A. Razis, H. Rykaczewski, H. Saka, A. Stepennov, M. Finger, A. Kveton, E. Carrera Jarrin, Y. Assran, B. El-mahdy, S. Elgammal, M. A. Mahmoud, Y. Mohammed, K. Ehataht, M. Kadastik, T. Lange, S. Nandan, C. Nielsen, J. Pata, M. Raidal, L. Tani, C. Veelken, H. Kirschenmann, K. Osterberg, M. Voutilainen, S. Bharthuar, N. Bin Norjoharuddeen, E. Brücken, F. Garcia, P. Inkaew, K. T. S. Kallonen, T. Lampén, K. Lassila-Perini, S. Lehti, T. Lindén, L. Martikainen, M. Myllymäki, M. m. Rantanen, H. Siikonen, J. Tuominiemi, P. Luukka, H. Petrow, M. Besancon, F. Couderc, M. Dejardin, D. Denegri, J. L. Faure, F. Ferri, S. Ganjour, P. Gras, G. Hamel de Monchenault, M. Kumar, V. Lohezic, J. Malcles, F. Orlandi, L. Portales, A. Rosowsky, M. Ö. Sahin, A. Savoy-Navarro, P. Simkina, M. Titov, M. Tornago, F. Beaudette, G. Boldrini, P. Busson, A. Cappati, C. Charlot, M. Chiusi, F. Damas, O. Davignon, A. De Wit, I. T. Ehle, B. A. Fontana Santos Alves, S. Ghosh, A. Gilbert, R. Granier de Cassagnac, A. Hakimi, B. Harikrishnan, L. Kalipoliti, G. Liu, M. Nguyen, C. Ochando, R. Salerno, J. B. Sauvan, Y. Sirois, L. Urda Gómez, E. Vernazza, A. Zabi, A. Zghiche, J.-L. Agram, J. Andrea, D. Apparu, D. Bloch, J.-M. Brom, E. C. Chabert, C. Collard, S. Falke, U. Goerlach, R. Haeberle, A.-C. Le Bihan, M. Meena, O. Poncet, G. Saha, M. A. Sessini, P. Van Hove, P. Vaucelle, A. Di Florio, D. Amram, S. Beauceron, B. Blancon, G. Boudoul, N. Chanon, D. Contardo, P. Depasse, C. Dozen, H. El Mamouni, J. Fay, S. Gascon, M. Gouzevitch, C. Greenberg, G. Grenier, B. Ille, E. Jourd‘huy, I. B. Laktineh, M. Lethuillier, L. Mirabito, S. Perries, A. Purohit, M. Vander Donckt, P. Verdier, J. Xiao, I. Lomidze, T. Toriashvili, Z. Tsamalaidze, V. Botta, S. Consuegra Rodríguez, L. Feld, K. Klein, M. Lipinski, D. Meuser, A. Pauls, D. Pérez Adán, N. Röwert, M. Teroerde, S. Diekmann, A. Dodonova, N. Eich, D. Eliseev, F. Engelke, J. Erdmann, M. Erdmann, P. Fackeldey, B. Fischer, T. Hebbeker, K. Hoepfner, F. Ivone, A. Jung, M. y. Lee, F. Mausolf, M. Merschmeyer, A. Meyer, S. Mukherjee, D. Noll, F. Nowotny, A. Pozdnyakov, Y. Rath, W. Redjeb, F. Rehm, H. Reithler, V. Sarkisovi, A. Schmidt, A. Sharma, J. L. Spah, A. Stein, F. Torres Da Silva De Araujo, S. Wiedenbeck, S. Zaleski, C. Dziwok, G. Flügge, T. Kress, A. Nowack, O. Pooth, A. Stahl, T. Ziemons, A. Zotz, H. Aarup Petersen, M. Aldaya Martin, J. Alimena, S. Amoroso, Y. An, J. Bach, S. Baxter, M. Bayatmakou, H. Becerril Gonzalez, O. Behnke, A. Belvedere, S. Bhattacharya, F. Blekman, K. Borras, A. Campbell, A. Cardini, C. Cheng, F. Colombina, M. De Silva, G. Eckerlin, D. Eckstein, L. I. Estevez Banos, O. Filatov, E. Gallo, A. Geiser, V. Guglielmi, M. Guthoff, A. Hinzmann, L. Jeppe, B. Kaech, M. Kasemann, C. Kleinwort, R. Kogler, M. Komm, D. Krücker, W. Lange, D. Leyva Pernia, K. Lipka, W. Lohmann, F. Lorkowski, R. Mankel, I.-A. Melzer-Pellmann, M. Mendizabal Morentin, A. B. Meyer, G. Milella, K. Moral Figueroa, A. Mussgiller, L. P. Nair, J. Niedziela, A. Nürnberg, Y. Otarid, J. Park, E. Ranken, A. Raspereza, D. Rastorguev, J. Rübenach, L. Rygaard, A. Saggio, M. Scham, S. Schnake, P. Schütze, C. Schwanenberger, D. Selivanova, K. Sharko, M. Shchedrolosiev, D. Stafford, F. Vazzoler, A. Ventura Barroso, R. Walsh, Q. Wang, Y. Wen, K. Wichmann, L. Wiens, C. Wissing, Y. Yang, A. Zimermmane Castro Santos, A. Albrecht, S. Albrecht, M. Antonello, S. Bein, L. Benato, S. Bollweg, M. Bonanomi, P. Connor, K. El Morabit, Y. Fischer, E. Garutti, A. Grohsjean, J. Haller, H. R. Jabusch, G. Kasieczka, P. Keicher, R. Klanner, W. Korcari, T. Kramer, C. c. Kuo, V. Kutzner, F. Labe, J. Lange, A. Lobanov, C. Matthies, L. Moureaux, M. Mrowietz, A. Nigamova, Y. Nissan, A. Paasch, K. J. Pena Rodriguez, T. Quadfasel, B. Raciti, M. Rieger, D. Savoiu, J. Schindler, P. Schleper, M. Schröder, J. Schwandt, M. Sommerhalder, H. Stadie, G. Steinbrück, A. Tews, M. Wolf, S. Brommer, M. Burkart, E. Butz, T. Chwalek, A. Dierlamm, A. Droll, N. Faltermann, M. Giffels, A. Gottmann, F. Hartmann, R. Hofsaess, M. Horzela, U. Husemann, J. Kieseler, M. Klute, R. Koppenhöfer, J. M. Lawhorn, M. Link, A. Lintuluoto, B. Maier, S. Maier, S. Mitra, M. Mormile, Th. Müller, M. Neukum, M. Oh, E. Pfeffer, M. Presilla, G. Quast, K. Rabbertz, B. Regnery, N. Shadskiy, I. Shvetsov, H. J. Simonis, L. Sowa, L. Stockmeier, K. Tauqeer, M. Toms, N. Trevisani, R. F. Von Cube, M. Wassmer, S. Wieland, F. Wittig, R. Wolf, X. Zuo, G. Anagnostou, G. Daskalakis, A. Kyriakis, A. Papadopoulos, A. Stakia, P. Kontaxakis, G. Melachroinos, Z. Painesis, I. Papavergou, I. Paraskevas, N. Saoulidou, K. Theofilatos, E. Tziaferi, K. Vellidis, I. Zisopoulos, G. Bakas, T. Chatzistavrou, G. Karapostoli, K. Kousouris, I. Papakrivopoulos, E. Siamarkou, G. Tsipolitis, A. Zacharopoulou, K. Adamidis, I. Bestintzanos, I. Evangelou, C. Foudas, C. Kamtsikis, P. Katsoulis, P. Kokkas, P. G. Kosmoglou Kioseoglou, N. Manthos, I. Papadopoulos, J. Strologas, C. Hajdu, D. Horvath, K. Márton, A. J. Rádl, F. Sikler, V. Veszpremi, M. Csanád, K. Farkas, A. Fehérkuti, M. M. A. Gadallah, Á. Kadlecsik, P. Major, G. Pásztor, G. I. Veres, B. Ujvari, G. Zilizi, G. Bencze, S. Czellar, J. Molnar, Z. Szillasi, T. Novak, J. Babbar, S. Bansal, S. B. Beri, V. Bhatnagar, G. Chaudhary, S. Chauhan, N. Dhingra, A. Kaur, H. Kaur, M. Kaur, S. Kumar, K. Sandeep, T. Sheokand, J. B. Singh, A. Singla, A. Ahmed, A. Bhardwaj, A. Chhetri, B. C. Choudhary, A. Kumar, M. Naimuddin, K. Ranjan, M. K. Saini, S. Saumya, S. Baradia, S. Barman, S. Das Gupta, S. Dutta, S. Sarkar, M. M. Ameen, P. K. Behera, S. C. Behera, G. Dash, P. Jana, P. Kalbhor, S. Kamble, J. R. Komaragiri, D. Kumar, P. R. Pujahari, N. R. Saha, A. K. Sikdar, R. K. Singh, P. Verma, S. Verma, A. Vijay, S. Dugad, G. B. Mohanty, B. Parida, M. Shelake, P. Suryadevara, A. Bala, S. Banerjee, R. M. Chatterjee, M. Guchait, Sh. Jain, A. Jaiswal, G. Majumder, K. Mazumdar, S. Parolia, A. Thachayath, S. Bahinipati, C. Kar, D. Maity, P. Mal, T. Mishra, V. K. Muraleedharan Nair Bindhu, K. Naskar, A. Nayak, S. Nayak, K. Pal, P. Sadangi, S. K. Swain, S. Varghese, D. Vats, S. Acharya, A. Alpana, S. Dube, B. Gomber, P. Hazarika, B. Kansal, A. Laha, B. Sahu, S. Sharma, K. Y. Vaish, H. Bakhshiansohi, A. Jafari, M. Zeinali, S. Bashiri, S. Chenarani, S. M. Etesami, Y. Hosseini, M. Khakzad, E. Khazaie, M. Mohammadi Najafabadi, S. Tizchang, M. Felcini, M. Grunewald, M. Abbrescia, A. Colaleo, D. Creanza, B. D’Anzi, N. De Filippis, M. De Palma, W. Elmetenawee, L. Fiore, G. Iaselli, L. Longo, M. Louka, G. Maggi, M. Maggi, I. Margjeka, V. Mastrapasqua, S. My, S. Nuzzo, A. Pellecchia, A. Pompili, G. Pugliese, R. Radogna, D. Ramos, A. Ranieri, L. Silvestris, F. M. Simone, Ü. Sözbilir, A. Stamerra, D. Troiano, R. Venditti, P. Verwilligen, A. Zaza, G. Abbiendi, C. Battilana, D. Bonacorsi, P. Capiluppi, F. R. Cavallo, M. Cuffiani, G. M. Dallavalle, T. Diotalevi, F. Fabbri, A. Fanfani, D. Fasanella, P. Giacomelli, L. Giommi, C. Grandi, L. Guiducci, S. Lo Meo, M. Lorusso, L. Lunerti, S. Marcellini, G. 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Salvatico, S. Sanders, C. Smith, G. Wilson, B. Allmond, R. Gujju Gurunadha, A. Ivanov, K. Kaadze, Y. Maravin, J. Natoli, D. Roy, G. Sorrentino, A. Baden, A. Belloni, J. Bistany-riebman, Y. M. Chen, S. C. Eno, N. J. Hadley, S. Jabeen, R. G. Kellogg, T. Koeth, B. Kronheim, Y. Lai, S. Lascio, A. C. Mignerey, S. Nabili, C. Palmer, C. Papageorgakis, M. M. Paranjpe, L. Wang, J. Bendavid, I. A. Cali, P. c. Chou, M. D’Alfonso, J. Eysermans, C. Freer, G. Gomez-Ceballos, M. Goncharov, G. Grosso, P. Harris, D. Hoang, D. Kovalskyi, J. Krupa, L. Lavezzo, Y.-J. Lee, K. Long, C. Mcginn, A. Novak, C. Paus, C. Roland, G. Roland, S. Rothman, G. S. F. Stephans, B. Wyslouch, T. J. Yang, B. Crossman, B. M. Joshi, C. Kapsiak, M. Krohn, D. Mahon, J. Mans, B. Marzocchi, M. Revering, R. Rusack, R. Saradhy, N. Strobbe, K. Bloom, D. R. Claes, G. Haza, J. Hossain, C. Joo, I. Kravchenko, J. E. Siado, W. Tabb, A. Vagnerini, A. Wightman, F. Yan, D. Yu, H. Bandyopadhyay, L. Hay, H. w. Hsia, I. Iashvili, A. Kalogeropoulos, A. Kharchilava, M. Morris, D. Nguyen, S. Rappoccio, H. Rejeb Sfar, A. Williams, P. Young, G. Alverson, E. Barberis, J. Bonilla, J. Dervan, Y. Haddad, Y. Han, A. Krishna, J. Li, M. Lu, G. Madigan, R. Mccarthy, D. M. Morse, V. Nguyen, T. Orimoto, A. Parker, L. Skinnari, D. Wood, J. Bueghly, S. Dittmer, K. A. Hahn, Y. Liu, Y. Miao, D. G. Monk, M. H. Schmitt, A. Taliercio, M. Velasco, G. Agarwal, R. Band, R. Bucci, S. Castells, A. Das, R. Goldouzian, M. Hildreth, K. W. Ho, K. Hurtado Anampa, T. Ivanov, C. Jessop, K. Lannon, J. Lawrence, N. Loukas, L. Lutton, J. Mariano, N. Marinelli, I. Mcalister, T. McCauley, C. Mcgrady, C. Moore, Y. Musienko, H. Nelson, M. Osherson, A. Piccinelli, R. Ruchti, A. Townsend, Y. Wan, M. Wayne, H. Yockey, M. Zarucki, L. Zygala, A. Basnet, B. Bylsma, M. Carrigan, L. S. Durkin, C. Hill, M. Joyce, M. Nunez Ornelas, K. Wei, B. L. Winer, B. R. Yates, H. Bouchamaoui, P. Das, G. Dezoort, P. Elmer, A. Frankenthal, B. Greenberg, N. Haubrich, K. Kennedy, G. Kopp, S. Kwan, D. Lange, A. Loeliger, D. Marlow, I. Ojalvo, J. Olsen, A. Shevelev, D. Stickland, C. Tully, S. Malik, A. S. Bakshi, S. Chandra, R. Chawla, A. Gu, L. Gutay, M. Jones, A. W. Jung, A. M. Koshy, M. Liu, G. Negro, N. Neumeister, G. Paspalaki, S. Piperov, V. Scheurer, J. F. Schulte, M. Stojanovic, J. Thieman, A. K. Virdi, F. Wang, W. Xie, J. Dolen, N. Parashar, A. Pathak, D. Acosta, T. Carnahan, K. M. Ecklund, P. J. Fernández Manteca, S. Freed, P. Gardner, F. J. M. Geurts, W. Li, J. Lin, O. Miguel Colin, B. P. Padley, R. Redjimi, J. Rotter, E. Yigitbasi, Y. Zhang, A. Bodek, P. de Barbaro, R. Demina, J. L. Dulemba, A. Garcia-Bellido, O. Hindrichs, A. Khukhunaishvili, N. Parmar, P. Parygin, E. Popova, R. Taus, B. Chiarito, J. P. Chou, S. V. Clark, D. Gadkari, Y. Gershtein, E. Halkiadakis, M. Heindl, C. Houghton, D. Jaroslawski, S. Konstantinou, I. Laflotte, A. Lath, R. Montalvo, K. Nash, J. Reichert, H. Routray, P. Saha, S. Salur, S. Schnetzer, S. Somalwar, R. Stone, S. A. Thayil, S. Thomas, J. Vora, H. Wang, D. Ally, A. G. Delannoy, S. Fiorendi, S. Higginbotham, T. Holmes, A. R. Kanuganti, N. Karunarathna, L. Lee, E. Nibigira, S. Spanier, D. Aebi, M. Ahmad, T. Akhter, O. Bouhali, R. Eusebi, J. Gilmore, T. Huang, T. Kamon, S. Luo, R. Mueller, D. Overton, D. Rathjens, A. Safonov, N. Akchurin, J. Damgov, N. Gogate, V. Hegde, A. Hussain, Y. Kazhykarim, K. Lamichhane, A. Mankel, T. Peltola, I. Volobouev, E. Appelt, Y. Chen, S. Greene, A. Gurrola, W. Johns, R. Kunnawalkam Elayavalli, A. Melo, F. Romeo, P. Sheldon, S. Tuo, J. Velkovska, J. Viinikainen, B. Cardwell, B. Cox, J. Hakala, R. Hirosky, A. Ledovskoy, C. Neu, P. E. Karchin, A. Aravind, K. Black, T. Bose, S. Dasu, I. De Bruyn, P. Everaerts, C. Galloni, H. He, M. Herndon, A. Herve, C. K. Koraka, A. Lanaro, R. Loveless, J. Madhusudanan Sreekala, A. Mallampalli, A. Mohammadi, G. Parida, L. Pétré, D. Pinna, A. Savin, V. Shang, W. H. Smith, D. Teague, H. F. Tsoi, W. Vetens, A. Warden, S. Afanasiev, V. Alexakhin, V. Andreev, Yu. Andreev, T. Aushev, M. Azarkin, A. Babaev, V. Blinov, E. Boos, V. Borshch, D. Budkouski, V. Bunichev, V. Chekhovsky, R. Chistov, M. Danilov, A. Dermenev, T. Dimova, D. Druzhkin, M. Dubinin, L. Dudko, A. Ershov, G. Gavrilov, V. Gavrilov, S. Gninenko, V. Golovtcov, N. Golubev, I. Golutvin, I. Gorbunov, A. Gribushin, Y. Ivanov, V. Kachanov, V. Karjavine, A. Karneyeu, V. Kim, M. Kirakosyan, D. Kirpichnikov, M. Kirsanov, V. Klyukhin, O. Kodolova, D. Konstantinov, V. Korenkov, A. Kozyrev, N. Krasnikov, A. Lanev, P. Levchenko, N. Lychkovskaya, V. Makarenko, A. Malakhov, V. Matveev, V. Murzin, A. Nikitenko, S. Obraztsov, V. Oreshkin, V. Palichik, V. Perelygin, M. Perfilov, S. Polikarpov, V. Popov, O. Radchenko, M. Savina, V. Savrin, V. Shalaev, S. Shmatov, S. Shulha, Y. Skovpen, S. Slabospitskii, V. Smirnov, D. Sosnov, V. Sulimov, A. Terkulov, O. Teryaev, I. Tlisova, A. Toropin, L. Uvarov, A. Uzunian, A. Vorobyev, G. Vorotnikov, N. Voytishin, B. S. Yuldashev, A. Zarubin, I. Zhizhin, and A. Zhokin

Subjects
Beyond Standard Model, Hadron-Hadron Scattering, Photon Production, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Results are presented from a search for new physics in high-mass diphoton events from proton-proton collisions at s $$ \sqrt{s} $$ = 13 TeV. The data set was collected in 2016–2018 with the CMS detector at the LHC and corresponds to an integrated luminosity of 138 fb −1. Events with a diphoton invariant mass greater than 500 GeV are considered. Two different techniques are used to predict the standard model backgrounds: parametric fits to the smoothly-falling background and a first-principles calculation of the standard model diphoton spectrum at next-to-next-to-leading order in perturbative quantum chromodynamics calculations. The first technique is sensitive to resonant excesses while the second technique can identify broad differences in the invariant mass shape. The data are used to constrain the production of heavy Higgs bosons, Randall-Sundrum gravitons, the large extra dimensions model of Arkani-Hamed, Dimopoulos, and Dvali (ADD), and the continuum clockwork mechanism. No statistically significant excess is observed. The present results are the strongest limits to date on ADD extra dimensions and RS gravitons with a coupling parameter greater than 0.1.

Published
2024
Full Text
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235. Unlocking the Genetic Secrets of Acromegaly: Exploring the Role of Genetics in a Rare Disorder

Author

Ioana Balinisteanu, Lavinia Caba, Andreea Florea, Roxana Popescu, Laura Florea, Maria-Christina Ungureanu, Letitia Leustean, Eusebiu Vlad Gorduza, and Cristina Preda

Subjects
acromegaly, genetics, PitNET, AIP, FIPA, GNAS, Biology (General), QH301-705.5
Abstract

Acromegaly is a rare endocrine disorder characterized by the excessive production of growth hormone (GH) in adulthood. Currently, it is understood that certain pituitary neuroendocrine tumors (PitNETs) exhibit a hereditary predisposition. These tumors’ genetic patterns fall into two categories: isolated and syndromic tumors. The isolated forms are characterized by molecular defects that predispose exclusively to PitNETs, including familial isolated pituitary adenomas (FIPAs) and sporadic genetic defects not characterized by hereditary predisposition. All the categories involve either germline or somatic mutations, or both, each associated with varying levels of penetrance and different phenotypes. This highlights the importance of genetic testing and the need for a more comprehensive view of the whole disease. Despite the availability of multiple treatment options, diagnosis often occurs after several years, and management is still difficult. Early detection and intervention are crucial for preventing complications and enhancing the quality of life for affected individuals. This review aims to elucidate the molecular, clinical, and histological characteristics of GH-secreting PitNETs, providing insights into their prevalence, treatment nuances, and the benefits of genetic testing for each type of genetic disorder associated with acromegaly.

Published
2024
Full Text
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236. Enhancing Language Learning: Designing Tests for Business English Students

Author

Alina Popescu

Subjects
assessment, test design, test development cycle, facility values, business english, Business, HF5001-6182, Economics as a science, HB71-74
Abstract

The present paper will focus on test design and development with a particular emphasis on how to devise comprehensive tests for students who attend a course on English for business (BE) purposes, a course which is aimed at enhancing students’ grammar, reading, vocabulary, and writing skills at B1 Level. In the introductory section, we are discussing the basic typology of tests as well as their purposes, with particular attention to assessing the skills of BE students. Special consideration will be given to the five phases used when devising a new BE test. Moreover, we will attempt to clarify several aspects concerning test-takers, i.e. BE students. The issues of grading and establishing optimal facility values of test items are also tackled. Some final recommendations on test design conclude our analysis.

Published
2024

237. Quality Strategies and Sustainability Measures in Romanian Spa Tourism

Author

Nicoleta Andreea Neacsu and Anca Popescu

Subjects
balneary tourism, quality strategies, spa tourism, sustainability measures, romania, Business, HF5001-6182, Economics as a science, HB71-74
Abstract

Balneary tourism represents an essential segment of the economy and the tourism sector, addressing essential requirements for maintaining health and well-being. Implementing quality strategies and sustainability measures is essential for thriving in a competitive environment and securing customer loyalty. This paper aims to identify the most relevant quality strategies and sustainability measures applied within the Romanian spa tourism market and their impact on attracting and retaining tourists. The research’s findings emphasize the critical role of quality and sustainability in boosting Romanian spa tourism’s competitiveness and attracting and retaining tourists. Spa tourism in Romania is valued for its therapeutic benefits, environmental quality, and year-round services, with recent economic growth leading to modernization. Quality strategies like ISO 9001:2015 certification, quality differentiation, and new technologies are crucial, though not widely recognized. Sustainability measures, such as efficient resource use, are increasingly necessary to consumers, enhancing the competitiveness of Romanian spa tourism.

Published
2024

238. QR Code Menus: Exploring the Role of QR Codes in Enhancing Operational Efficiency and Customer Engagement in Restaurants and Cafes

Author

Anca Popescu and Nicoleta Andreea Neacsu

Subjects
qr codes, hospitality industry, digital menus, restaurants, cafes, Business, HF5001-6182, Economics as a science, HB71-74
Abstract

Many of the industries need to adopt digital technologies to improve the overall activity. The hospitality industry is no exception, one of the means which enables the businesses to enhance their services and the interaction with customers is the use of QR codes. The purpose of the article was to explore the effects of the QR codes adoption in the activities of restaurants and cafes, emphasizing its important role in improving operational processes. The research performed among various restaurant and cafes owners, using semi-structured interviews, investigated how the QR codes were integrated in the day-to-day activity and the perceived impact. Furthermore, it explored the benefits, challenges and the plans for using this technology. The results provided a detailed analysis on how the QR codes were integrated, offering useful insights on how digital tools are improving businesses and the relationship with the customers.

Published
2024

239. Measurement of multijet azimuthal correlations and determination of the strong coupling in proton-proton collisions at $$\sqrt{s}=13\,\text {Te}\hspace{-.08em}\text {V} $$ s = 13 Te V

Author

CMS Collaboration, A. Hayrapetyan, A. Tumasyan, W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, K. Damanakis, M. Dragicevic, P. S. Hussain, M. Jeitler, N. Krammer, A. Li, D. Liko, I. Mikulec, J. Schieck, R. Schöfbeck, D. Schwarz, M. Sonawane, S. Templ, W. Waltenberger, C.-E. Wulz, M. R. Darwish, T. Janssen, P. Van Mechelen, E. S. Bols, J. D’Hondt, S. Dansana, A. De Moor, M. Delcourt, H. El Faham, S. Lowette, I. Makarenko, D. Müller, A. R. Sahasransu, S. Tavernier, M. Tytgat, G. P. Van Onsem, S. Van Putte, D. Vannerom, B. Clerbaux, A. K. Das, G. De Lentdecker, L. Favart, D. Hohov, J. Jaramillo, A. Khalilzadeh, K. Lee, M. Mahdavikhorrami, A. Malara, S. Paredes, L. Pétré, N. Postiau, L. Thomas, M. Vanden Bemden, C. Vander Velde, P. Vanlaer, M. De Coen, D. Dobur, Y. Hong, J. Knolle, L. Lambrecht, G. Mestdach, K. Mota Amarilo, C. Rendón, A. Samalan, K. Skovpen, N. Van Den Bossche, J. van der Linden, L. Wezenbeek, A. Benecke, A. Bethani, G. Bruno, C. Caputo, C. Delaere, I. S. Donertas, A. Giammanco, K. Jaffel, Sa. Jain, V. Lemaitre, J. Lidrych, P. Mastrapasqua, K. Mondal, T. T. Tran, S. Wertz, G. A. Alves, E. Coelho, C. Hensel, T. Menezes De Oliveira, A. Moraes, P. Rebello Teles, M. Soeiro, W. L. Aldá Júnior, M. Alves Gallo Pereira, M. Barroso Ferreira Filho, H. Brandao Malbouisson, W. Carvalho, J. Chinellato, E. M. Da Costa, G. G. Da Silveira, D. De Jesus Damiao, S. Fonseca De Souza, R. Gomes De Souza, J. Martins, C. Mora Herrera, L. Mundim, H. Nogima, A. Santoro, A. Sznajder, M. Thiel, A. Vilela Pereira, C. A. Bernardes, L. Calligaris, T. R. Fernandez Perez Tomei, E. M. Gregores, P. G. Mercadante, S. F. Novaes, B. Orzari, Sandra S. Padula, A. Aleksandrov, G. Antchev, R. Hadjiiska, P. Iaydjiev, M. Misheva, M. Shopova, G. Sultanov, A. Dimitrov, L. Litov, B. Pavlov, P. Petkov, A. Petrov, E. Shumka, S. Keshri, S. Thakur, T. Cheng, Q. Guo, T. Javaid, L. Yuan, Z. Hu, J. Liu, K. Yi, G. M. Chen, H. S. Chen, M. Chen, F. Iemmi, C. H. Jiang, A. Kapoor, H. Liao, Z.-A. Liu, R. Sharma, J. N. Song, J. Tao, C. Wang, J. Wang, Z. Wang, H. Zhang, A. Agapitos, Y. Ban, A. Levin, C. Li, Q. Li, Y. Mao, S. J. Qian, X. Sun, D. Wang, H. Yang, L. Zhang, C. Zhou, Z. You, N. Lu, G. Bauer, X. Gao, D. Leggat, H. Okawa, Z. Lin, C. Lu, M. Xiao, C. Avila, D. A. Barbosa Trujillo, A. Cabrera, C. Florez, J. Fraga, J. A. Reyes Vega, J. Mejia Guisao, F. Ramirez, M. Rodriguez, J. D. Ruiz Alvarez, D. Giljanovic, N. Godinovic, D. Lelas, A. Sculac, M. Kovac, T. Sculac, P. Bargassa, V. Brigljevic, B. K. Chitroda, D. Ferencek, S. Mishra, A. Starodumov, T. Susa, A. Attikis, K. Christoforou, S. Konstantinou, J. Mousa, C. Nicolaou, F. Ptochos, P. A. Razis, H. Rykaczewski, H. Saka, A. Stepennov, M. Finger, A. Kveton, E. Ayala, E. Carrera Jarrin, A. A. Abdelalim, E. Salama, M. A. Mahmoud, Y. Mohammed, K. Ehataht, M. Kadastik, T. Lange, S. Nandan, C. Nielsen, J. Pata, M. Raidal, L. Tani, C. Veelken, H. Kirschenmann, K. Osterberg, M. Voutilainen, S. Bharthuar, E. Brücken, F. Garcia, K. T. S. Kallonen, R. Kinnunen, T. Lampén, K. Lassila-Perini, S. Lehti, T. Lindén, L. Martikainen, M. Myllymäki, M. m. Rantanen, H. Siikonen, E. Tuominen, J. Tuominiemi, P. Luukka, H. Petrow, M. Besancon, F. Couderc, M. Dejardin, D. Denegri, J. L. Faure, F. Ferri, S. Ganjour, P. Gras, G. Hamel de Monchenault, V. Lohezic, J. Malcles, J. Rander, A. Rosowsky, M. Ö. Sahin, A. Savoy-Navarro, P. Simkina, M. Titov, M. Tornago, C. Baldenegro Barrera, F. Beaudette, A. Buchot Perraguin, P. Busson, A. Cappati, C. Charlot, F. Damas, O. Davignon, A. De Wit, B. A. Fontana Santos Alves, S. Ghosh, A. Gilbert, R. Granier de Cassagnac, A. Hakimi, B. Harikrishnan, L. Kalipoliti, G. Liu, J. Motta, M. Nguyen, C. Ochando, L. Portales, R. Salerno, J. B. Sauvan, Y. Sirois, A. Tarabini, E. Vernazza, A. Zabi, A. Zghiche, J.-L. Agram, J. Andrea, D. Apparu, D. Bloch, J.-M. Brom, E. C. Chabert, C. Collard, S. Falke, U. Goerlach, C. Grimault, R. Haeberle, A.-C. Le Bihan, M. Meena, G. Saha, M. A. Sessini, P. Van Hove, S. Beauceron, B. Blancon, G. Boudoul, N. Chanon, J. Choi, D. Contardo, P. Depasse, C. Dozen, H. El Mamouni, J. Fay, S. Gascon, M. Gouzevitch, C. Greenberg, G. Grenier, B. Ille, I. B. Laktineh, M. Lethuillier, L. Mirabito, S. Perries, A. Purohit, M. Vander Donckt, P. Verdier, J. Xiao, I. Lomidze, T. Toriashvili, Z. Tsamalaidze, V. Botta, L. Feld, K. Klein, M. Lipinski, D. Meuser, A. Pauls, N. Röwert, M. Teroerde, S. Diekmann, A. Dodonova, N. Eich, D. Eliseev, F. Engelke, J. Erdmann, M. Erdmann, P. Fackeldey, B. Fischer, T. Hebbeker, K. Hoepfner, F. Ivone, A. Jung, M. y. Lee, L. Mastrolorenzo, F. Mausolf, M. Merschmeyer, A. Meyer, S. Mukherjee, D. Noll, A. Novak, F. Nowotny, A. Pozdnyakov, Y. Rath, W. Redjeb, F. Rehm, H. Reithler, U. Sarkar, V. Sarkisovi, A. Schmidt, A. Sharma, J. L. Spah, A. Stein, F. Torres Da Silva De Araujo, L. Vigilante, S. Wiedenbeck, S. Zaleski, C. Dziwok, G. Flügge, W. Haj Ahmad, T. Kress, A. Nowack, O. Pooth, A. Stahl, T. Ziemons, A. Zotz, H. Aarup Petersen, M. Aldaya Martin, J. Alimena, S. Amoroso, Y. An, S. Baxter, M. Bayatmakou, H. Becerril Gonzalez, O. Behnke, A. Belvedere, S. Bhattacharya, F. Blekman, K. Borras, A. Campbell, A. Cardini, C. Cheng, F. Colombina, S. Consuegra Rodríguez, G. Correia Silva, M. De Silva, G. Eckerlin, D. Eckstein, L. I. Estevez Banos, O. Filatov, E. Gallo, A. Geiser, A. Giraldi, G. Greau, V. Guglielmi, M. Guthoff, A. Hinzmann, A. Jafari, L. Jeppe, N. Z. Jomhari, B. Kaech, M. Kasemann, C. Kleinwort, R. Kogler, M. Komm, D. Krücker, W. Lange, D. Leyva Pernia, K. Lipka, W. Lohmann, R. Mankel, I.-A. Melzer-Pellmann, M. Mendizabal Morentin, A. B. Meyer, G. Milella, A. Mussgiller, L. P. Nair, A. Nürnberg, Y. Otarid, J. Park, D. Pérez Adán, E. Ranken, A. Raspereza, B. Ribeiro Lopes, J. Rübenach, A. Saggio, M. Scham, S. Schnake, P. Schütze, C. Schwanenberger, D. Selivanova, K. Sharko, M. Shchedrolosiev, R. E. Sosa Ricardo, D. Stafford, F. Vazzoler, A. Ventura Barroso, R. Walsh, Q. Wang, Y. Wen, K. Wichmann, L. Wiens, C. Wissing, Y. Yang, A. Zimermmane Castro Santos, A. Albrecht, S. Albrecht, M. Antonello, S. Bein, L. Benato, M. Bonanomi, P. Connor, M. Eich, K. El Morabit, Y. Fischer, A. Fröhlich, C. Garbers, E. Garutti, A. Grohsjean, M. Hajheidari, J. Haller, H. R. Jabusch, G. Kasieczka, P. Keicher, R. Klanner, W. Korcari, T. Kramer, V. Kutzner, F. Labe, J. Lange, A. Lobanov, C. Matthies, A. Mehta, L. Moureaux, M. Mrowietz, A. Nigamova, Y. Nissan, A. Paasch, K. J. Pena Rodriguez, T. Quadfasel, B. Raciti, M. Rieger, D. Savoiu, J. Schindler, P. Schleper, M. Schröder, J. Schwandt, M. Sommerhalder, H. Stadie, G. Steinbrück, A. Tews, M. Wolf, S. Brommer, M. Burkart, E. Butz, T. Chwalek, A. Dierlamm, A. Droll, N. Faltermann, M. Giffels, A. Gottmann, F. Hartmann, R. Hofsaess, M. Horzela, U. Husemann, J. Kieseler, M. Klute, R. Koppenhöfer, J. M. Lawhorn, M. Link, A. Lintuluoto, S. Maier, S. Mitra, M. Mormile, Th. Müller, M. Neukum, M. Oh, M. Presilla, G. Quast, K. Rabbertz, B. 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Rawal, D. Rosenzweig, S. Rosenzweig, K. Shi, T. Adams, A. Al Kadhim, A. Askew, N. Bower, R. Habibullah, V. Hagopian, R. Hashmi, R. S. Kim, T. Kolberg, G. Martinez, H. Prosper, P. R. Prova, M. Wulansatiti, R. Yohay, J. Zhang, B. Alsufyani, M. M. Baarmand, S. Butalla, T. Elkafrawy, M. Hohlmann, R. Kumar Verma, M. Rahmani, E. Yanes, M. R. Adams, A. Baty, C. Bennett, R. Cavanaugh, R. Escobar Franco, O. Evdokimov, C. E. Gerber, D. J. Hofman, J. h. Lee, D. S. Lemos, A. H. Merrit, C. Mills, S. Nanda, G. Oh, B. Ozek, D. Pilipovic, R. Pradhan, T. Roy, S. Rudrabhatla, M. B. Tonjes, N. Varelas, Z. Ye, M. Alhusseini, D. Blend, K. Dilsiz, L. Emediato, G. Karaman, O. K. Köseyan, J.-P. Merlo, A. Mestvirishvili, J. Nachtman, O. Neogi, H. Ogul, Y. Onel, A. Penzo, C. Snyder, E. Tiras, B. Blumenfeld, L. Corcodilos, J. Davis, A. V. Gritsan, L. Kang, S. Kyriacou, P. Maksimovic, M. Roguljic, J. Roskes, S. Sekhar, M. Swartz, A. Abreu, L. F. Alcerro Alcerro, J. Anguiano, P. Baringer, A. Bean, Z. Flowers, D. Grove, J. King, G. Krintiras, M. Lazarovits, C. Le Mahieu, C. Lindsey, J. Marquez, N. Minafra, M. Murray, M. Nickel, M. Pitt, S. Popescu, C. Rogan, C. Royon, R. Salvatico, S. Sanders, C. Smith, G. Wilson, B. Allmond, A. Ivanov, K. Kaadze, A. Kalogeropoulos, Y. Maravin, K. Nam, J. Natoli, D. Roy, G. Sorrentino, F. Rebassoo, D. Wright, A. Baden, A. Belloni, Y. M. Chen, S. C. Eno, N. J. Hadley, S. Jabeen, R. G. Kellogg, T. Koeth, Y. Lai, S. Lascio, A. C. Mignerey, S. Nabili, C. Palmer, C. Papageorgakis, M. M. Paranjpe, L. Wang, J. Bendavid, W. Busza, I. A. Cali, M. D’Alfonso, J. Eysermans, C. Freer, G. Gomez-Ceballos, M. Goncharov, G. Grosso, P. Harris, D. Hoang, D. Kovalskyi, J. Krupa, L. Lavezzo, Y.-J. Lee, K. Long, C. Mironov, C. Paus, D. Rankin, C. Roland, G. Roland, S. Rothman, G. S. F. Stephans, B. Wyslouch, T. J. Yang, B. Crossman, B. M. Joshi, C. Kapsiak, M. Krohn, D. Mahon, J. Mans, B. Marzocchi, S. Pandey, M. Revering, R. Rusack, R. Saradhy, N. Schroeder, N. Strobbe, M. A. Wadud, L. M. Cremaldi, K. Bloom, D. R. Claes, G. Haza, J. Hossain, C. Joo, I. Kravchenko, J. E. Siado, W. Tabb, A. Vagnerini, A. Wightman, F. Yan, D. Yu, H. Bandyopadhyay, L. Hay, I. Iashvili, A. Kharchilava, M. Morris, D. Nguyen, S. Rappoccio, H. Rejeb Sfar, A. Williams, G. Alverson, E. Barberis, J. Dervan, Y. Haddad, Y. Han, A. Krishna, J. Li, M. Lu, G. Madigan, R. Mccarthy, D. M. Morse, V. Nguyen, T. Orimoto, A. Parker, L. Skinnari, A. Tishelman-Charny, B. Wang, D. Wood, J. Bueghly, Z. Chen, S. Dittmer, K. A. Hahn, Y. Liu, Y. Miao, D. G. Monk, M. H. Schmitt, A. Taliercio, M. Velasco, G. Agarwal, R. Band, R. Bucci, S. Castells, A. Das, R. Goldouzian, M. Hildreth, K. W. Ho, K. Hurtado Anampa, T. Ivanov, C. Jessop, K. Lannon, J. Lawrence, N. Loukas, L. Lutton, J. Mariano, N. Marinelli, I. Mcalister, T. McCauley, C. Mcgrady, C. Moore, Y. Musienko, H. Nelson, M. Osherson, A. Piccinelli, R. Ruchti, A. Townsend, Y. Wan, M. Wayne, H. Yockey, M. Zarucki, L. Zygala, A. Basnet, B. Bylsma, M. Carrigan, L.S. Durkin, C. Hill, M. Joyce, M. Nunez Ornelas, K. Wei, B. L. Winer, B. R. Yates, F. M. Addesa, H. Bouchamaoui, P. Das, G. Dezoort, P. Elmer, A. Frankenthal, B. Greenberg, N. Haubrich, G. Kopp, S. Kwan, D. Lange, A. Loeliger, D. Marlow, I. Ojalvo, J. Olsen, A. Shevelev, D. Stickland, C. Tully, A. S. Bakshi, V. E. Barnes, S. Chandra, R. Chawla, S. Das, A. Gu, L. Gutay, M. Jones, A. W. Jung, D. Kondratyev, A. M. Koshy, M. Liu, G. Negro, N. Neumeister, G. Paspalaki, S. Piperov, V. Scheurer, J. F. Schulte, M. Stojanovic, J. Thieman, A. K. Virdi, F. Wang, W. Xie, J. Dolen, N. Parashar, A. Pathak, D. Acosta, T. Carnahan, K. M. Ecklund, P. J. Fernández Manteca, S. Freed, P. Gardner, F. J. M. Geurts, W. Li, O. Miguel Colin, B. P. Padley, R. Redjimi, J. Rotter, E. Yigitbasi, Y. Zhang, A. Bodek, P. de Barbaro, R. Demina, J. L. Dulemba, A. Garcia-Bellido, O. Hindrichs, A. Khukhunaishvili, N. Parmar, P. Parygin, E. Popova, R. Taus, K. Goulianos, B. Chiarito, J. P. Chou, Y. Gershtein, E. Halkiadakis, A. Hart, M. Heindl, D. Jaroslawski, O. Karacheban, I. Laflotte, A. Lath, R. Montalvo, K. Nash, H. Routray, S. Salur, S. Schnetzer, S. Somalwar, R. Stone, S. A. Thayil, S. Thomas, J. Vora, H. Wang, H. Acharya, D. Ally, A. G. Delannoy, S. Fiorendi, S. Higginbotham, T. Holmes, A. R. Kanuganti, N. Karunarathna, L. Lee, E. Nibigira, S. Spanier, D. Aebi, M. Ahmad, O. Bouhali, R. Eusebi, J. Gilmore, T. Huang, T. Kamon, S. Luo, R. Mueller, D. Overton, D. Rathjens, A. Safonov, N. Akchurin, J. Damgov, V. Hegde, A. Hussain, Y. Kazhykarim, K. Lamichhane, A. Mankel, T. Peltola, I. Volobouev, A. Whitbeck, E. Appelt, Y. Chen, S. Greene, A. Gurrola, W. Johns, R. Kunnawalkam Elayavalli, A. Melo, F. Romeo, P. Sheldon, S. Tuo, J. Velkovska, J. Viinikainen, B. Cardwell, B. Cox, J. Hakala, R. Hirosky, A. Ledovskoy, C. Neu, C. E. Perez Lara, P. E. Karchin, A. Aravind, K. Black, T. Bose, S. Dasu, I. De Bruyn, P. Everaerts, C. Galloni, H. He, M. Herndon, A. Herve, C. K. Koraka, A. Lanaro, R. Loveless, J. Madhusudanan Sreekala, A. Mallampalli, A. Mohammadi, G. Parida, D. Pinna, A. Savin, V. Shang, W. H. Smith, D. Teague, H. F. Tsoi, W. Vetens, A. Warden, S. Afanasiev, V. Andreev, Yu. Andreev, T. Aushev, M. Azarkin, A. Babaev, V. Blinov, E. Boos, V. Borshch, D. Budkouski, M. Chadeeva, V. Chekhovsky, R. Chistov, A. Dermenev, T. Dimova, D. Druzhkin, M. Dubinin, L. Dudko, A. Ershov, G. Gavrilov, V. Gavrilov, S. Gninenko, V. Golovtcov, N. Golubev, I. Golutvin, I. Gorbunov, Y. Ivanov, V. Kachanov, V. Karjavine, A. Karneyeu, V. Kim, M. Kirakosyan, D. Kirpichnikov, M. Kirsanov, V. Klyukhin, O. Kodolova, V. Korenkov, A. Kozyrev, N. Krasnikov, A. Lanev, P. Levchenko, O. Lukina, N. Lychkovskaya, V. Makarenko, A. Malakhov, V. Matveev, V. Murzin, A. Nikitenko, S. Obraztsov, V. Oreshkin, V. Palichik, V. Perelygin, S. Petrushanko, S. Polikarpov, V. Popov, O. Radchenko, M. Savina, V. Savrin, V. Shalaev, S. Shmatov, S. Shulha, Y. Skovpen, S. Slabospitskii, V. Smirnov, A. Snigirev, D. Sosnov, V. Sulimov, E. Tcherniaev, A. Terkulov, O. Teryaev, I. Tlisova, A. Toropin, L. Uvarov, A. Uzunian, I. Vardanyan, A. Vorobyev, N. Voytishin, B. S. Yuldashev, A. Zarubin, I. Zhizhin, and A. Zhokin

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract A measurement is presented of a ratio observable that provides a measure of the azimuthal correlations among jets with large transverse momentum $$p_{\textrm{T}}$$ p T . This observable is measured in multijet events over the range of $$p_{\textrm{T}} = 360$$ p T = 360 – $$3170\,\text {Ge}\hspace{-.08em}\text {V} $$ 3170 Ge V based on data collected by the CMS experiment in proton-proton collisions at a centre-of-mass energy of 13 $$\,\text {Te}\hspace{-.08em}\text {V}$$ Te V , corresponding to an integrated luminosity of 134 $$\,\text {fb}^{-1}$$ fb - 1 . The results are compared with predictions from Monte Carlo parton-shower event generator simulations, as well as with fixed-order perturbative quantum chromodynamics (pQCD) predictions at next-to-leading-order (NLO) accuracy obtained with different parton distribution functions (PDFs) and corrected for nonperturbative and electroweak effects. Data and theory agree within uncertainties. From the comparison of the measured observable with the pQCD prediction obtained with the NNPDF3.1 NLO PDFs, the strong coupling at the Z boson mass scale is $$\alpha _\textrm{S} (m_{{\textrm{Z}}}) =0.1177 \pm 0.0013\, \text {(exp)} _{-0.0073}^{+0.0116} \,\text {(theo)} = 0.1177_{-0.0074}^{+0.0117}$$ α S ( m Z ) = 0.1177 ± 0.0013 (exp) - 0.0073 + 0.0116 (theo) = 0 . 1177 - 0.0074 + 0.0117 , where the total uncertainty is dominated by the scale dependence of the fixed-order predictions. A test of the running of $$\alpha _\textrm{S}$$ α S in the $$\,\text {Te}\hspace{-.08em}\text {V}$$ Te V region shows no deviation from the expected NLO pQCD behaviour.

Published
2024
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240. Expression of Vascular Adhesion Protein-1 and Thrombospondin-1 in Gingival Crevicular Fluid of Patients with Periodontitis and Non-Alcoholic Fatty Liver Disease

Author

Pitru A, Gheorghe DN, Popescu DM, Nicolae FM, Boldeanu MV, Turcu-Stiolica A, Arsenie CC, Surlin P, Cazacu SM, and Rogoveanu I

Subjects
non-alcoholic fatty liver disease, periodontitis, vap-1, tsp-1, gingival crevicular fluid, periodontal disease., Pathology, RB1-214, Therapeutics. Pharmacology, RM1-950
Abstract

Allma Pitru,1 Dorin Nicolae Gheorghe,2 Dora Maria Popescu,2 Flavia Mirela Nicolae,2 Mihail Virgil Boldeanu,3 Adina Turcu-Stiolica,4 Cristian Cosmin Arsenie,5 Petra Surlin,2 Sergiu Marian Cazacu,6 Ion Rogoveanu6 1Oral Pathology Department, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Craiova, 200349, Romania; 2Department of Periodontology, Research Center of Periodontal-Systemic Interactions, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Craiova, 200349, Romania; 3Department of Immunology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Craiova, 200349, Romania; 4Department of Pharmacoeconomics and Statistical Analysis, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Craiova, 200349, Romania; 5Doctoral School, University of Medicine and Pharmacy of Craiova, Craiova, 200349, Romania; 6Department of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Craiova, 200349, RomaniaCorrespondence: Petra Surlin, Department of Periodontology, Research Center of Periodontal-Systemic Interactions, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Craiova, 200349, Romania, Email surlinpetra@gmail.com Sergiu Marian Cazacu, Department of Gastroenterology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Craiova, 200349, Romania, Email sergiucazacu@umfcv.comPurpose: Non-alcoholic fatty liver disease (NAFLD) represents a heterogeneous spectrum of liver diseases that encompass simple steatosis, non-alcoholic steatohepatitis (NASH), and advanced fibrosis or cirrhosis. Periodontitis is a chronic infectious disease with multiple causal factors that presents a complex interaction between the microbial biofilm and the host’s immune response. The aim of this study was to investigate the concentrations of Vascular Adhesion Protein-1 (VAP-1) and Thrombospondin-1 (TSP-1) in patients with coexisting periodontitis and NAFLD.Patients and Methods: This study included 48 patients, who were dental and periodontal assessed. Of these patients, 25 were diagnosed with NAFLD. After performing the periodontal clinical examination, gingival crevicular fluid (GCF) samples were collected. Enzyme-linked immunosorbent assay (ELISA) dedicated kits tests were used for the detection and quantitative determination of VAP-1 and TSP-1 in GCF samples. Statistical methods were applied for the comparison and correlation of data.Results: VAP-1 and TSP-1 levels showed significant differences between all test and control groups (p< 0.0001). Statistically significant correlations (p< 0.05) between VAP-1 and periodontal and liver parameters were found in patients with NAFLD and periodontitis.Conclusion: Periodontal inflammation is more marked in patients with periodontitis-NAFLD association. Vascular adhesion and angiogenesis could be affected in patients with periodontitis and NAFLD. These findings could suggest that addressing periodontal inflammation in individuals with the periodontitis-NAFLD association may have a broader impact on vascular adhesion and angiogenesis, highlighting the interplay between oral health and liver conditions for comprehensive patient care.Keywords: non-alcoholic fatty liver disease, periodontitis, VAP-1, TSP-1, gingival crevicular fluid, periodontal disease

Published
2024

241. Efficient Method for Rapid Diagnosis of Streptococcal Pneumoniae in the Context of Co-Infection in Children-Case Report

Author

Stavar-Matei L, Mihailov OM, Crestez AM, Alexandru AM, Popescu CM, and Nechita A

Subjects
co-infections, pneumococcal urinary antigen test, therapeutic management, vaccination, Pediatrics, RJ1-570
Abstract

Loredana Stavar-Matei,1,2 Oana-Mariana Mihailov,1 Alexandra-Mihaela Crestez,1,2 Anamaria Madalina Alexandru,1 Cristina-Mihaela Popescu,1,2 Aurel Nechita1,2 1Dunarea de Jos” University of Galati, Faculty of Medicine and Pharmacy, Galati,Romania; 2Sf. Ioan“ Children’s Clinical Emergency Hospital, Galati, RomaniaCorrespondence: Loredana Stavar-Matei, Email mateiloredana23@yahoo.comBackground: Bacterial pneumonia caused by Streptococcus pneumoniae continues to be one of the most common medical conditions in the pediatric population under 5 years of age, sometimes requiring prolonged hospitalizations and high costs. The time period (3 to 7 days) from the collection of biological samples (ie nasal exudate, pharyngeal exudate, sputum, blood culture and various secretions) to the arrival of the results has been a much discussed issue. Thus, the use of a rapid diagnostic test for Streptococcus pneumoniae urinary antigen, which is easy to use, may lead after the result is known to a targeted therapeutic management and thus to a favorable prognosis of the disease for the patient.Methods: This case report presents the case of a 4 years and 5 months old patient diagnosed with invasive pneumococcal-associated pneumococcal infection in the context of SARS-COV2 infection.Results: The clinical course was slowly favorable with complications that required a long hospitalization.Conclusion: In conclusion, some rapid diagnostic techniques, clinician judgment and some prevention methods, such as vaccination, can improve a patient’s quality of life. One prospect for the future would be the development of new vaccines covering other aggressive Streptococcus pneumoniae serotypes.Keywords: co-infections, pneumococcal urinary antigen test, therapeutic management, vaccination

Published
2024

242. Solution-derived Ge–Sb–Se–Te phase-change chalcogenide films

Author

Myungkoo Kang, Rashi Sharma, Cesar Blanco, Daniel Wiedeman, Quentin Altemose, Patrick E. Lynch, Gil B. J. Sop Tagne, Yifei Zhang, Mikhail Y. Shalaginov, Cosmin-Constantin Popescu, Brandon M. Triplett, Clara Rivero-Baleine, Casey M. Schwarz, Anuradha M. Agarwal, Tian Gu, Juejun Hu, and Kathleen A. Richardson

Subjects
Medicine, Science
Abstract

Abstract Ge–Sb–Se–Te chalcogenides, namely Se-substituted Ge–Sb–Te, have been developed as an alternative optical phase change material (PCM) with a high figure-of-merit. A need for the integration of such new PCMs onto a variety of photonic platforms has necessitated the development of fabrication processes compatible with diverse material compositions as well as substrates of varying material types, shapes, and sizes. This study explores the application of chemical solution deposition as a method capable of creating conformally coated layers and delves into the resulting modifications in the structural and optical properties of Ge–Sb–Se–Te PCMs. Specifically, we detail the solution-based deposition of Ge–Sb–Se–Te layers and present a comparative analysis with those deposited via thermal evaporation. We also discuss our ongoing endeavor to improve available choice of processing-material combinations and how to realize solution-derived high figure-of-merit optical PCM layers, which will enable a new era for the development of reconfigurable photonic devices.

Published
2024
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243. Undergraduate occupational medicine education in European Medical Schools: better training to meet today’s challenges

Author

Marcos Larrosa, Petar Bulat, Nicole Majery, Jean-François Gehanno, Elena-Ana Păuncu, Marjolein Bastiaanssen, Lode Godderis, Isabel Iguacel, Florina Georgeta Popescu, Soile Jungewelter, Lutgart Braeckman, and Begoña Martínez-Jarreta

Subjects
Medical education, Undergraduate teaching, Occupational medicine, Europe, Special aspects of education, LC8-6691, Medicine
Abstract

Abstract Background Occupational medicine (OM) faces considerable challenges today, one of them related to the university training of future physicians considered suboptimal at a global level as it has been pointed out in many studies. The aim of this study is to update the state of OM medical education in European universities. Methods Between March and August 2022, an e-mail survey regarding OM training to undergraduate medical students was conducted among OM professors at European universities in 28 countries (n = 347). Results Of the 347 universities, 53 medical schools from 19 countries responded (response rate = 15.3%). In 89% of cases, OM was taught. The average number of hours per academic year was 24.3, with significant variation within the same country. Lectures were the most popular teaching technique (98%), with a considerable use of modern approaches such as problem-based learning (61%), and e-learning (57%). While occupational diseases and principles of prevention were covered, other subjects such as the environmental impact or collaboration with an OM physician were poorly represented in the educational program. Conclusion According to data, several European medical schools may provide insufficient OM education and training to their students. The education of undergraduate occupational medicine students in European medical schools should be designed to equip them with the knowledge and skills required to meet today’s challenges. It is critical that undergraduate OM education in European medical schools be enhanced, harmonized, and standardized.

Published
2024
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244. Constraints on anomalous Higgs boson couplings from its production and decay using the WW channel in proton–proton collisions at $$\sqrt{s} = 13~\text {TeV}$$ s = 13 TeV

Author

CMS Collaboration, A. Hayrapetyan, A. Tumasyan, W. Adam, J. W. Andrejkovic, T. Bergauer, S. Chatterjee, K. Damanakis, M. Dragicevic, P. S. Hussain, M. Jeitler, N. Krammer, A. Li, D. Liko, I. Mikulec, J. Schieck, R. Schöfbeck, D. Schwarz, M. Sonawane, S. Templ, W. Waltenberger, C.-E. Wulz, M. R. Darwish, T. Janssen, P. Van Mechelen, E. S. Bols, J. D’Hondt, S. Dansana, A. De Moor, M. Delcourt, H. El Faham, S. Lowette, I. Makarenko, D. Müller, A. R. Sahasransu, S. Tavernier, M. Tytgat, G. P. Van Onsem, S. Van Putte, D. Vannerom, B. Clerbaux, A. K. Das, G. De Lentdecker, L. Favart, P. Gianneios, D. Hohov, J. Jaramillo, A. Khalilzadeh, K. Lee, M. Mahdavikhorrami, A. Malara, S. Paredes, L. Pétré, N. Postiau, L. Thomas, M. Vanden Bemden, C. Vander Velde, P. Vanlaer, M. De Coen, D. Dobur, Y. Hong, J. Knolle, L. Lambrecht, G. Mestdach, K. Mota Amarilo, C. Rendón, A. Samalan, K. Skovpen, N. Van Den Bossche, J. van der Linden, L. Wezenbeek, A. Benecke, A. Bethani, G. Bruno, C. Caputo, C. Delaere, I. S. Donertas, A. Giammanco, K. Jaffel, Sa. Jain, V. Lemaitre, J. Lidrych, P. Mastrapasqua, K. Mondal, T. T. Tran, S. Wertz, G. A. Alves, E. Coelho, C. Hensel, T. Menezes De Oliveira, A. Moraes, P. Rebello Teles, M. Soeiro, W. L. Aldá Júnior, M. Alves Gallo Pereira, M. Barroso Ferreira Filho, H. Brandao Malbouisson, W. Carvalho, J. Chinellato, E. M. Da Costa, G. G. Da Silveira, D. De Jesus Damiao, S. Fonseca De Souza, R. Gomes De Souza, J. Martins, C. Mora Herrera, L. Mundim, H. Nogima, J. P. Pinheiro, A. Santoro, A. Sznajder, M. Thiel, A. Vilela Pereira, C. A. Bernardes, L. Calligaris, T. R. Fernandez Perez Tomei, E. M. Gregores, P. G. Mercadante, S. F. Novaes, B. Orzari, Sandra S. Padula, A. Aleksandrov, G. Antchev, R. Hadjiiska, P. Iaydjiev, M. Misheva, M. Shopova, G. Sultanov, A. Dimitrov, L. Litov, B. Pavlov, P. Petkov, A. Petrov, E. Shumka, S. Keshri, S. Thakur, T. Cheng, T. Javaid, L. Yuan, Z. Hu, J. Liu, K. Yi, G. M. Chen, H. S. Chen, M. Chen, F. Iemmi, C. H. Jiang, A. Kapoor, H. Liao, Z.-A. Liu, R. Sharma, J. N. Song, J. Tao, C. Wang, J. Wang, Z. Wang, H. Zhang, A. Agapitos, Y. Ban, A. Levin, C. Li, Q. Li, Y. Mao, S. J. Qian, X. Sun, D. Wang, H. Yang, L. Zhang, C. Zhou, Z. You, N. Lu, G. Bauer, X. Gao, D. Leggat, H. Okawa, Z. Lin, C. Lu, M. Xiao, C. Avila, D. A. Barbosa Trujillo, A. Cabrera, C. Florez, J. Fraga, J. A. Reyes Vega, J. Mejia Guisao, F. Ramirez, M. Rodriguez, J. D. Ruiz Alvarez, D. Giljanovic, N. Godinovic, D. Lelas, A. Sculac, M. Kovac, T. Sculac, P. Bargassa, V. Brigljevic, B. K. Chitroda, D. Ferencek, S. Mishra, A. Starodumov, T. Susa, A. Attikis, K. Christoforou, S. Konstantinou, J. Mousa, C. Nicolaou, F. Ptochos, P. A. Razis, H. Rykaczewski, H. Saka, A. Stepennov, M. Finger, A. Kveton, E. Ayala, E. Carrera Jarrin, S. Elgammal, A. Ellithi Kamel, M. A. Mahmoud, Y. Mohammed, K. Ehataht, M. Kadastik, T. Lange, S. Nandan, C. Nielsen, J. Pata, M. Raidal, L. Tani, C. Veelken, H. Kirschenmann, K. Osterberg, M. Voutilainen, S. Bharthuar, E. Brücken, F. Garcia, K. T. S. Kallonen, R. Kinnunen, T. Lampén, K. Lassila-Perini, S. Lehti, T. Lindén, L. Martikainen, M. Myllymäki, M. M. Rantanen, H. Siikonen, E. Tuominen, J. Tuominiemi, P. Luukka, H. Petrow, M. Besancon, F. Couderc, M. Dejardin, D. Denegri, J. L. Faure, F. Ferri, S. Ganjour, P. Gras, G. Hamel de Monchenault, V. Lohezic, J. Malcles, J. Rander, A. Rosowsky, M. Ö. Sahin, A. Savoy-Navarro, P. Simkina, M. Titov, M. Tornago, C. Baldenegro Barrera, F. Beaudette, A. Buchot Perraguin, P. Busson, A. Cappati, C. Charlot, M. Chiusi, F. Damas, O. Davignon, A. De Wit, B. A. Fontana Santos Alves, S. Ghosh, A. Gilbert, R. Granier de Cassagnac, A. Hakimi, B. Harikrishnan, L. Kalipoliti, G. Liu, J. Motta, M. Nguyen, C. Ochando, L. Portales, R. Salerno, J. B. Sauvan, Y. Sirois, A. Tarabini, E. Vernazza, A. Zabi, A. Zghiche, J.-L. Agram, J. Andrea, D. Apparu, D. Bloch, J.-M. Brom, E. C. Chabert, C. Collard, S. Falke, U. Goerlach, C. Grimault, R. Haeberle, A.-C. 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Brown, O. Buchmuller, V. Cacchio, C. A. Carrillo Montoya, G. S. Chahal, D. Colling, J. S. Dancu, I. Das, P. Dauncey, G. Davies, J. Davies, M. Della Negra, S. Fayer, G. Fedi, G. Hall, M. H. Hassanshahi, A. Howard, G. Iles, M. Knight, J. Langford, J. León Holgado, L. Lyons, A.-M. Magnan, S. Malik, M. Mieskolainen, J. Nash, M. Pesaresi, B. C. Radburn-Smith, A. Richards, A. Rose, K. Savva, C. Seez, R. Shukla, A. Tapper, K. Uchida, G. P. Uttley, L. H. Vage, T. Virdee, M. Vojinovic, N. Wardle, D. Winterbottom, K. Coldham, J. E. Cole, A. Khan, P. Kyberd, I. D. Reid, S. Abdullin, A. Brinkerhoff, B. Caraway, J. Dittmann, K. Hatakeyama, J. Hiltbrand, B. McMaster, M. Saunders, S. Sawant, C. Sutantawibul, J. Wilson, R. Bartek, A. Dominguez, C. Huerta Escamilla, A. E. Simsek, R. Uniyal, A. M. Vargas Hernandez, B. Bam, R. Chudasama, S. I. Cooper, S. V. Gleyzer, C. U. Perez, P. Rumerio, E. Usai, R. Yi, A. Akpinar, D. Arcaro, C. Cosby, Z. Demiragli, C. Erice, C. Fangmeier, C. Fernandez Madrazo, E. Fontanesi, D. Gastler, F. Golf, S. Jeon, I. Reed, J. Rohlf, K. Salyer, D. Sperka, D. Spitzbart, I. Suarez, A. Tsatsos, S. Yuan, A. G. Zecchinelli, G. Benelli, X. Coubez, D. Cutts, M. Hadley, U. Heintz, J. M. Hogan, T. Kwon, G. Landsberg, K. T. Lau, D. Li, J. Luo, S. Mondal, M. Narain, N. Pervan, S. Sagir, F. Simpson, M. Stamenkovic, W. Y. Wong, X. Yan, W. Zhang, S. Abbott, J. Bonilla, C. Brainerd, R. Breedon, M. Calderon De La Barca Sanchez, M. Chertok, M. Citron, J. Conway, P. T. Cox, R. Erbacher, F. Jensen, O. Kukral, G. Mocellin, M. Mulhearn, D. Pellett, W. Wei, Y. Yao, F. Zhang, M. Bachtis, R. Cousins, A. Datta, G. Flores Avila, J. Hauser, M. Ignatenko, M. A. Iqbal, T. Lam, E. Manca, A. Nunez Del Prado, D. Saltzberg, V. Valuev, R. Clare, J. W. Gary, M. Gordon, G. Hanson, W. Si, S. Wimpenny, J. G. Branson, S. Cittolin, S. Cooperstein, D. Diaz, J. Duarte, L. Giannini, J. Guiang, R. Kansal, V. Krutelyov, R. Lee, J. Letts, M. Masciovecchio, F. Mokhtar, M. Pieri, M. Quinnan, B. V. Sathia Narayanan, V. Sharma, M. Tadel, E. Vourliotis, F. Würthwein, Y. Xiang, A. Yagil, A. Barzdukas, L. Brennan, C. Campagnari, A. Dorsett, J. Incandela, A. J. Li, P. Masterson, H. Mei, J. Richman, U. Sarica, R. Schmitz, F. Setti, J. Sheplock, D. Stuart, T.Á. Vámi, S. Wang, A. Bornheim, O. Cerri, A. Latorre, J. Mao, H. B. Newman, M. Spiropulu, J. R. Vlimant, S. Xie, R. Y. Zhu, J. Alison, S. An, M. B. Andrews, P. Bryant, M. Cremonesi, V. Dutta, T. Ferguson, A. Harilal, C. Liu, T. Mudholkar, S. Murthy, P. Palit, M. Paulini, A. Roberts, A. Sanchez, W. Terrill, J. P. Cumalat, W. T. Ford, A. Hart, A. Hassani, G. Karathanasis, E. MacDonald, N. Manganelli, A. Perloff, C. Savard, N. Schonbeck, K. Stenson, K. A. Ulmer, S. R. Wagner, N. Zipper, J. Alexander, S. Bright-Thonney, X. Chen, D. J. Cranshaw, J. Fan, X. Fan, D. Gadkari, S. Hogan, P. Kotamnives, J. Monroy, M. Oshiro, J. R. Patterson, J. Reichert, M. Reid, A. Ryd, J. Thom, P. Wittich, R. Zou, M. Albrow, M. Alyari, O. Amram, G. Apollinari, A. Apresyan, L. A. T. Bauerdick, D. Berry, J. Berryhill, P. C. Bhat, K. Burkett, J. N. Butler, A. Canepa, G. B. Cerati, H. W. K. Cheung, F. Chlebana, G. Cummings, J. Dickinson, I. Dutta, V. D. Elvira, Y. Feng, J. Freeman, A. Gandrakota, Z. Gecse, L. Gray, D. Green, A. Grummer, S. Grünendahl, D. Guerrero, O. Gutsche, R. M. Harris, R. Heller, T. C. Herwig, J. Hirschauer, L. Horyn, B. Jayatilaka, S. Jindariani, M. Johnson, U. Joshi, T. Klijnsma, B. Klima, K. H. M. Kwok, S. Lammel, D. Lincoln, R. Lipton, T. Liu, C. Madrid, K. Maeshima, C. Mantilla, D. Mason, P. McBride, P. Merkel, S. Mrenna, S. Nahn, J. Ngadiuba, D. Noonan, V. Papadimitriou, N. Pastika, K. Pedro, C. Pena, F. Ravera, A. Reinsvold Hall, L. Ristori, E. Sexton-Kennedy, N. Smith, A. Soha, L. Spiegel, S. Stoynev, J. Strait, L. Taylor, S. Tkaczyk, N. V. Tran, L. Uplegger, E. W. Vaandering, I. Zoi, C. Aruta, P. Avery, D. Bourilkov, L. Cadamuro, P. Chang, V. Cherepanov, R. D. Field, E. Koenig, M. Kolosova, J. Konigsberg, A. Korytov, K. H. Lo, K. Matchev, N. Menendez, G. Mitselmakher, K. Mohrman, A. Muthirakalayil Madhu, N. Rawal, D. Rosenzweig, S. Rosenzweig, K. Shi, T. Adams, A. Al Kadhim, A. Askew, S. Bower, R. Habibullah, V. Hagopian, R. Hashmi, R. S. Kim, T. Kolberg, G. Martinez, H. Prosper, P. R. Prova, M. Wulansatiti, R. Yohay, J. Zhang, B. Alsufyani, M. M. Baarmand, S. Butalla, T. Elkafrawy, M. Hohlmann, R. Kumar Verma, M. Rahmani, E. Yanes, M. R. Adams, A. Baty, C. Bennett, R. Cavanaugh, R. Escobar Franco, O. Evdokimov, C. E. Gerber, D. J. Hofman, J. H. Lee, D. S. Lemos, A. H. Merrit, C. Mills, S. Nanda, G. Oh, B. Ozek, D. Pilipovic, R. Pradhan, T. Roy, S. Rudrabhatla, M. B. Tonjes, N. Varelas, Z. Ye, M. Alhusseini, D. Blend, K. Dilsiz, L. Emediato, G. Karaman, O. K. Köseyan, J.-P. Merlo, A. Mestvirishvili, J. Nachtman, O. Neogi, H. Ogul, Y. Onel, A. Penzo, C. Snyder, E. Tiras, B. Blumenfeld, L. Corcodilos, J. Davis, A. V. Gritsan, L. Kang, S. Kyriacou, P. Maksimovic, M. Roguljic, J. Roskes, S. Sekhar, M. Swartz, A. Abreu, L. F. Alcerro Alcerro, J. Anguiano, P. Baringer, A. Bean, Z. Flowers, D. Grove, J. King, G. Krintiras, M. Lazarovits, C. Le Mahieu, C. Lindsey, J. Marquez, N. Minafra, M. Murray, M. Nickel, M. Pitt, S. Popescu, C. Rogan, C. Royon, R. Salvatico, S. Sanders, C. Smith, G. Wilson, B. Allmond, A. Ivanov, K. Kaadze, A. Kalogeropoulos, Y. Maravin, K. Nam, J. Natoli, D. Roy, G. Sorrentino, F. Rebassoo, D. Wright, A. Baden, A. Belloni, Y. M. Chen, S. C. Eno, N. J. Hadley, S. Jabeen, R. G. Kellogg, T. Koeth, Y. Lai, S. Lascio, A. C. Mignerey, S. Nabili, C. Palmer, C. Papageorgakis, M. M. Paranjpe, L. Wang, J. Bendavid, I. A. Cali, M. D’Alfonso, J. Eysermans, C. Freer, G. Gomez-Ceballos, M. Goncharov, G. Grosso, P. Harris, D. Hoang, D. Kovalskyi, J. Krupa, L. Lavezzo, Y.-J. Lee, K. Long, C. Mironov, A. Novak, C. Paus, D. Rankin, C. Roland, G. Roland, S. Rothman, G. S. F. Stephans, B. Wyslouch, T. J. Yang, B. Crossman, B. M. Joshi, C. Kapsiak, M. Krohn, D. Mahon, J. Mans, B. Marzocchi, S. Pandey, M. Revering, R. Rusack, R. Saradhy, N. Schroeder, N. Strobbe, M. A. Wadud, L. M. Cremaldi, K. Bloom, D. R. Claes, G. Haza, J. Hossain, C. Joo, I. Kravchenko, J. E. Siado, W. Tabb, A. Vagnerini, A. Wightman, F. Yan, D. Yu, H. Bandyopadhyay, L. Hay, I. Iashvili, A. Kharchilava, M. Morris, D. Nguyen, S. Rappoccio, H. Rejeb Sfar, A. Williams, G. Alverson, E. Barberis, J. Dervan, Y. Haddad, Y. Han, A. Krishna, J. Li, M. Lu, G. Madigan, R. Mccarthy, D. M. Morse, V. Nguyen, T. Orimoto, A. Parker, L. Skinnari, A. Tishelman-Charny, B. Wang, D. Wood, J. Bueghly, Z. Chen, S. Dittmer, K. A. Hahn, Y. Liu, Y. Miao, D. G. Monk, M. H. Schmitt, A. Taliercio, M. Velasco, G. Agarwal, R. Band, R. Bucci, S. Castells, A. Das, R. Goldouzian, M. Hildreth, K. W. Ho, K. Hurtado Anampa, T. Ivanov, C. Jessop, K. Lannon, J. Lawrence, N. Loukas, L. Lutton, J. Mariano, N. Marinelli, I. Mcalister, T. McCauley, C. Mcgrady, C. Moore, Y. Musienko, H. Nelson, M. Osherson, A. Piccinelli, R. Ruchti, A. Townsend, Y. Wan, M. Wayne, H. Yockey, M. Zarucki, L. Zygala, A. Basnet, B. Bylsma, M. Carrigan, L. S. Durkin, C. Hill, M. Joyce, M. Nunez Ornelas, K. Wei, B. L. Winer, B. R. Yates, F. M. Addesa, H. Bouchamaoui, P. Das, G. Dezoort, P. Elmer, A. Frankenthal, B. Greenberg, N. Haubrich, G. Kopp, S. Kwan, D. Lange, A. Loeliger, D. Marlow, I. Ojalvo, J. Olsen, A. Shevelev, D. Stickland, C. Tully, A. S. Bakshi, V. E. Barnes, S. Chandra, R. Chawla, S. Das, A. Gu, L. Gutay, M. Jones, A. W. Jung, D. Kondratyev, A. M. Koshy, M. Liu, G. Negro, N. Neumeister, G. Paspalaki, S. Piperov, V. Scheurer, J. F. Schulte, M. Stojanovic, J. Thieman, A. K. Virdi, F. Wang, W. Xie, J. Dolen, N. Parashar, A. Pathak, D. Acosta, T. Carnahan, K. M. Ecklund, P. J. Fernández Manteca, S. Freed, P. Gardner, F. J. M. Geurts, W. Li, O. Miguel Colin, B. P. Padley, R. Redjimi, J. Rotter, E. Yigitbasi, Y. Zhang, A. Bodek, P. de Barbaro, R. Demina, J. L. Dulemba, A. Garcia-Bellido, O. Hindrichs, A. Khukhunaishvili, N. Parmar, P. Parygin, E. Popova, R. Taus, K. Goulianos, B. Chiarito, J. P. Chou, Y. Gershtein, E. Halkiadakis, M. Heindl, D. Jaroslawski, O. Karacheban, I. Laflotte, A. Lath, R. Montalvo, K. Nash, H. Routray, S. Salur, S. Schnetzer, S. Somalwar, R. Stone, S. A. Thayil, S. Thomas, J. Vora, H. Wang, H. Acharya, D. Ally, A. G. Delannoy, S. Fiorendi, S. Higginbotham, T. Holmes, A. R. Kanuganti, N. Karunarathna, L. Lee, E. Nibigira, S. Spanier, D. Aebi, M. Ahmad, O. Bouhali, R. Eusebi, J. Gilmore, T. Huang, T. Kamon, S. Luo, R. Mueller, D. Overton, D. Rathjens, A. Safonov, N. Akchurin, J. Damgov, V. Hegde, A. Hussain, Y. Kazhykarim, K. Lamichhane, A. Mankel, T. Peltola, I. Volobouev, A. Whitbeck, E. Appelt, Y. Chen, S. Greene, A. Gurrola, W. Johns, R. Kunnawalkam Elayavalli, A. Melo, F. Romeo, P. Sheldon, S. Tuo, J. Velkovska, J. Viinikainen, B. Cardwell, B. Cox, J. Hakala, R. Hirosky, A. Ledovskoy, C. Neu, C. E. Perez Lara, P. E. Karchin, A. Aravind, K. Black, T. Bose, S. Dasu, I. De Bruyn, P. Everaerts, C. Galloni, H. He, M. Herndon, A. Herve, C. K. Koraka, A. Lanaro, R. Loveless, J. Madhusudanan Sreekala, A. Mallampalli, A. Mohammadi, G. Parida, D. Pinna, A. Savin, V. Shang, W. H. Smith, D. Teague, H. F. Tsoi, W. Vetens, A. Warden, S. Afanasiev, V. Andreev, Yu. Andreev, T. Aushev, M. Azarkin, A. Babaev, V. Blinov, E. Boos, V. Borshch, D. Budkouski, V. Chekhovsky, R. Chistov, M. Danilov, A. Dermenev, T. Dimova, D. Druzhkin, M. Dubinin, L. Dudko, A. Ershov, G. Gavrilov, V. Gavrilov, S. Gninenko, V. Golovtcov, N. Golubev, I. Golutvin, I. Gorbunov, A. Gribushin, Y. Ivanov, V. Kachanov, V. Karjavine, A. Karneyeu, V. Kim, M. Kirakosyan, D. Kirpichnikov, M. Kirsanov, V. Klyukhin, O. Kodolova, V. Korenkov, A. Kozyrev, N. Krasnikov, A. Lanev, P. Levchenko, N. Lychkovskaya, V. Makarenko, A. Malakhov, V. Matveev, V. Murzin, A. Nikitenko, S. Obraztsov, V. Oreshkin, V. Palichik, V. Perelygin, S. Petrushanko, S. Polikarpov, V. Popov, O. Radchenko, M. Savina, V. Savrin, V. Shalaev, S. Shmatov, S. Shulha, Y. Skovpen, S. Slabospitskii, V. Smirnov, A. Snigirev, D. Sosnov, V. Sulimov, E. Tcherniaev, A. Terkulov, O. Teryaev, I. Tlisova, A. Toropin, L. Uvarov, A. Uzunian, A. Vorobyev, N. Voytishin, B. S. Yuldashev, A. Zarubin, I. Zhizhin, and A. Zhokin

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract A study of the anomalous couplings of the Higgs boson to vector bosons, including $${\textit{CP}}$$ CP -violation effects, has been conducted using its production and decay in the WW channel. This analysis is performed on proton–proton collision data collected with the CMS detector at the CERN LHC during 2016–2018 at a center-of-mass energy of 13 TeV, and corresponds to an integrated luminosity of 138 $$\,\text {fb}^{-1}$$ fb - 1 . The different-flavor dilepton $$({\textrm{e}} {{\upmu }})$$ ( e μ ) final state is analyzed, with dedicated categories targeting gluon fusion, electroweak vector boson fusion, and associated production with a W or Z boson. Kinematic information from associated jets is combined using matrix element techniques to increase the sensitivity to anomalous effects at the production vertex. A simultaneous measurement of four Higgs boson couplings to electroweak vector bosons is performed in the framework of a standard model effective field theory. All measurements are consistent with the expectations for the standard model Higgs boson and constraints are set on the fractional contribution of the anomalous couplings to the Higgs boson production cross section.

Published
2024
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245. EFECTUL ANTIHIPERTENSIV AL INHIBITORULUI SGLT2 - DAPAGLIFLOZINA LA PACIENȚII CU DIABET ZAHARAT TIP 2

Author

Ana COTELEA, Maria COCIU, Liuba POPESCU, Anna MOISEEVA, and Alexandru CARAUȘ

Subjects
dapagliflozina, hipertensiune arterială rezistentă la tratament, diabet zaharat tip 2, Medicine (General), R5-920, Internal medicine, RC31-1245, Other systems of medicine, RZ201-999, Public aspects of medicine, RA1-1270
Abstract

Patologiile cronice invalidizante în timp , precum hipertensiunea arterială și diabetul zaharat tip 2 ramîn a fi în topul țintelor studiilor și abordărilor la nivel internațional. De aceea, oamenilor de știință , precum și personalului din cadrul bazelor practice nu le rămîne altceva decît să impună dezvoltarea si implementarea noilor preparate, care ar fi în stare să răspundă necesităților acestora. Un pas important ar fi sintetizarea moleculelor medicamentoase cu efecte pozitive în patologii concomitente, care de cele mai multe ori se întalnesc în perechi sau se complementează prin efectele adverse pe care le produc asupra organismului uman. Un astfel de preparat, care este la moment abordat prin prisma multitudinei efectelor benefice - este în plină companie de implementare în tratamentul a mai multor patologii cornice ca- diabet zaharat tip 2, insuficiența cardiacă cronică, insuficiența renală cronică si face parte din grupa inhibitorilor SGLT 2 este dapagliflozina.Efectul antihipertensiv al dapagliflozinei este relevant si impune o analiză bine documentată în această direcție

Published
2024
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246. UNELE DILEME CLINICE IN MEDICATIA CU INHIBITORII SISTEMULUI RENINA-ANGIOTENSINA-ALDOSTERONA LA PACIENTII CU INSUFICENTA CARDIACA

Author

Liuba POPESCU and Alexandru CARAUȘ

Subjects
nhibitorii sistemului renina-angiotensina-aldosterona, insuficenta cardiaca, hiperkaliemie, Medicine (General), R5-920, Internal medicine, RC31-1245, Other systems of medicine, RZ201-999, Public aspects of medicine, RA1-1270
Abstract

Utilizarea inhibitorilor sistemului renină-angiotensină-aldosteron la pacienții cu insuficiență cardiacă și fracție de ejecție redusă este asociată cu ameliorarea capacitatii funcționale, o creștere a calității si sperantei de viața percepute, o rata de deces cardiovascular scazuta și o reducere a numărului de spitalizări din exacerbarea insuficientei cardiace. Unele dintre aceste medicamente sunt, de asemenea, eficiente la pacienții cu boală renală cronică și albuminurie, precum și la pacienții cu hipertensiune arterială rezistentă. În ciuda numeroaselor beneficii, inhibitorii sistemului renină-angiotensină- aldosteron sau asociat cu creșterea incidenței hiperkalemiei, în special la pacienții cu boală cronică de rinichi concomitenta. Hiperkalemia este o tulburare electrolitică comună care este definită ca o creștere a concentrațiilor plasmatice de potasiu peste 5 mEq/L. Hiperkalemia s-a asociat cu cresterea ratei de respitalizari, aritmii maligne și o creștere a mortalității. Pe de altă parte, tratamentul optimizat cu inhibitorii sistemului renină-angiotensină-aldosteron necesită creșteri progresive ale dozei care pot determina, la rândul lor, o probabilitate mai mare de hiperkaliemie. Din toate aceste motive, aducem recomandarile ghidului de conduita și tratament pentru aceasta categorie de pacienti.

Published
2024
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247. NOI PERSPECTIVE ÎN TEMPERAREA HIPERTENSIUNII ARTERIALE REZISTENTE LA TRATAMENTNOI PERSPECTIVE ÎN TEMPERAREA HIPERTENSIUNII ARTERIALE REZISTENTE LA TRATAMENT

Author

Alexandru CARAUȘ, Maria COCIU, Anna MOISEEVA, and Liuba POPESCU

Subjects
hipertensiune arterială rezistentă la tratament, aprocicentan, firibastat, baxdrostat, desimpatizarea arterelor renale, Medicine (General), R5-920, Internal medicine, RC31-1245, Other systems of medicine, RZ201-999, Public aspects of medicine, RA1-1270
Abstract

Datele prezentate fac parte componentă a reviului de literatură/rezultatele obținute în cadrul proiectului instituțional cu acronimul DIAFEREZIS. Hipertensiunea arterială (HTA) rezistentă la tratament reprezintă o povară semnificativă pentru sistemele de sănătate din întreaga lume datorită asocierii sale cu un risc cardiovascular extrem de ridicat și rămâne o dificultate terapeutică determinată de căi fiziopatologice complexe și insuficient abordate de terapia convențională. O serie de medicamente aflate în diferite stadii de investigare ar putea avea un impact semnificativ pe viitor asupra tratamentului HTA rezistente la tratament. Pe linga terapia farmacologică, studiile arată dovezi promițătoare în privința desimpatizării arterelor renale (DSAR) în gestionarea HTA rezistente. Utilizarea mai bună a terapiilor aprobate în prezent și integrarea terapiilor emergente sunt completări binevenite în arsenalul terapeutic antihipertensiv.

Published
2024
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248. Before and Beyond COVID-19: The Interplay of Corruption, Logistics, and Economic Growth in the EU through the RBV Lens

Author

Alexandra-Codruța BÎZOI (Popescu) and Cristian-Gabriel BÎZOI

Subjects
corruption, logistics performance, economic development, eu member states, covid-19, rbv, Economics as a science, HB71-74, Business records management, HF5735-5746
Abstract

This study explores the complex interplay between corruption, economic growth, and logistics performance in EU nations, utilizing a mixed-method approach and data from pre- and post-pandemic periods. Applying the Resource-Based View (RBV) and Qualitative Comparative Analysis (QCA), it identifies critical conditions impacting GDP growth, highlighting the intertwined roles of pre-pandemic logistics and corruption perceptions. The findings, relevant for policymakers, underscore the importance of robust governance in navigating economic challenges. This novel approach combines RBV and QCA, offering insights into the dynamics of financial and logistical landscapes during global upheavals.

Published
2024
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249. A systematic review on the most common injuries in handball

Author

Gîtman Roxana-Maria, Breha Alexandru Mihai, Mihăilă Ion, Iconaru Ioana, Popescu Corina, and Ciucurel Constantin

Subjects
injuries, handball, prevention, epidemiology, specific literature, specific criteria, Education, Education (General), L7-991
Abstract

High performance in sports requires lots of training and a good knowledge of training techniques, characteristics of physical training, mechanisms of lesion occurrence and methods of prevention sports pathology. Handball specific requirements are very important in order to avoid specific trauma, and in this matter specific literature is very important for specialists. This paper aimed to find how many relevant papers were published from 2018 to present regarding handball injuries and prevention of handball injuries, in two databases, PUBMED and Library Genesis (libgen.li.). For this matter there were used three equations to find results in the two databases selected, and for each of them there were quantified the number of scientific papers that were relevant to this study. Also, in this paper we presented inclusion/exclusion criteria, the results we found, and also, the analysis of each paper’s quality, for the papers that were a match to the inclusion criteria. For each paper we evaluated the quality of content using 5 relevant questions that help us understand the missing aspects that need further study, being applied individually for the two databases. The results we found revealed a very poor literature regarding injuries in handball and also prevention of injury in handball.

Published
2024
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250. Smart Non-Intrusive Appliance Load-Monitoring System Based on Phase Diagram Analysis

Author

Denis Stanescu, Florin Enache, and Florin Popescu

Subjects
non-intrusive load-monitoring, appliance signature, NIALM, load management, smart grid, phase diagram, Engineering (General). Civil engineering (General), TA1-2040
Abstract

Much of today’s power grid was designed and built using technologies and organizational principles developed decades ago. The lack of energy resources and classic power networks are the main causes of the development of the smart grid to efficiently use energy resources, with stable and safe operation. In such a network, one of the fundamental priorities is provided by non-intrusive appliance load monitoring (NIALM) in order to analyze, recognize and determine the electricity consumption of each consumer. In this paper, we propose a new smart system approach for the characterization of the appliance load signature based on a data-driven method, namely the phase diagram. Our aim is to use the non-intrusive load monitoring of appliances in order to recognize different types of consumers that can exist within a smart building.

Published
2024
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