Search

Your search keyword '"PANG Yan"' showing total 1,818 results
Start Over Author "PANG Yan"
1,818 results on '"PANG Yan"'

201. Creativity Theory

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

202. Mathematical Gesture Theory

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

203. Music Without Scores

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

204. Frege’s Prison of Functions

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

206. The MIDI Code

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

207. Global Music

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

208. What Is Art?

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

209. De Saussure’s Six Dichotomies

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

210. Physical Reality

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

211. Mental Reality

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, O’Brien, Margaret, Torunsky, Nathan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, Pang, Yan, O'Brien, Margaret, and Torunsky, Nathan

Published
2016
Full Text
View/download PDF

212. Gestures

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

213. Categories

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

214. Solutions of Exercises

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

215. Performance

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

216. Matrices

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

217. Permutation Groups

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

218. Just Tuning

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

219. Rings and Fields

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

220. Nerves

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

221. Modulation Theory

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

222. Coltrane’s Giant Steps

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

225. Recursion

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

227. Complex Numbers

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

228. Integers

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

229. Natural Numbers

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

230. Universal Properties

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

232. Functions and Relations

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

233. Real Numbers

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

234. The Architecture of Sets

Author

Mazzola, Guerino, Mannone, Maria, Pang, Yan, Mazzola, Guerino, Managing editor, Andreatta, Moreno, Managing editor, Mannone, Maria, and Pang, Yan

Published
2016
Full Text
View/download PDF

237. Identification of arnicolide C as a novel chemosensitizer to suppress mTOR/E2F1/FANCD2 axis in non‐small cell lung cancer.

Author

Chen, Yu‐Fei, Pang, Yan‐Chun, Wang, Han‐Chen, Wu, Pei‐En, Chen, Zi‐Jie, Huang, Da, Peng, Dong‐Ling, Yan, Yong‐Ming, Liu, Changhui, Wu, Li‐Chuan, Fan, Xiang‐Zhen, Cheng, Yong‐Xian, and Liu, Yong‐Qiang

Subjects
*NON-small-cell lung carcinoma, *DNA repair, *SMALL interfering RNA, *FANCONI'S anemia, *MITOMYCIN C, *IDENTIFICATION
Abstract

Background and Purpose: The mammalian target of rapamycin (mTOR) pathway plays critical roles in intrinsic chemoresistance by regulating Fanconi anaemia complementation group D2 (FANCD2) expression. However, the mechanisms by which mTOR regulates FANCD2 expression and related inhibitors are not clearly elucidated. Extracts of Centipeda minima (C. minima) showed promising chemosensitizing effects by inhibiting FANCD2 activity. Here, we have aimed to identify the bioactive chemosensitizer in C. minima extracts and elucidate its underlying mechanism. Experimental Approach: The chemosensitizing effects of arnicolide C (ArC), a bioactive compound in C. minima, on non‐small cell lung cancer (NSCLC) were investigated using immunoblotting, immunofluorescence, flow cytometry, the comet assay, small interfering RNA (siRNA) transfection and animal models. The online SynergyFinder software was used to determine the synergistic effects of ArC and chemotherapeutic drugs on NSCLC cells. Key Results: ArC had synergistic cytotoxic effects with DNA cross‐linking drugs such as cisplatin and mitomycin C in NSCLC cells. ArC treatment markedly decreased FANCD2 expression in NSCLC cells, thus attenuating cisplatin‐induced FANCD2 nuclear foci formation, leading to DNA damage and apoptosis. ArC inhibited the mTOR pathway and attenuated mTOR‐mediated expression of E2F1, a critical transcription factor of FANCD2. Co‐administration of ArC and cisplatin exerted synergistic anticancer effects in the A549 xenograft mouse model by suppressing mTOR/FANCD2 signalling in tumour tissues. Conclusion and Implications: ArC suppressed DNA cross‐linking drug‐induced DNA damage response by inhibiting the mTOR/E2F1/FANCD2 signalling axis, serving as a chemosensitizing agent. This provides insight into the anticancer mechanisms of ArC and offers a potential combinatorial anticancer therapeutic strategy. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

247. The Future of Music

Author

Mazzola, Guerino, primary, Noer, Jason, additional, Pang, Yan, additional, Yao, Shuhui, additional, Afrisando, Jay, additional, Rochester, Christopher, additional, and Neace, William, additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results