1,344 results on '"P. Robitaille"'
Search Results
202. SED modeling of Young Massive Stars
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Robitaille, Thomas P.
- Subjects
Astrophysics - Abstract
In this contribution, I review the applications and potential limitations of the spectral energy distribution fitting tool that I have developed, with a strong emphasis on the limits to which this tool can be used to improve our understanding of massive star formation. I discuss why our current grid of models cannot be used to distinguish between the several competing theories of massive star formation. I also discuss stellar mass determinations, artificial correlations between parameters in the grid of models, multiplicity, confusion, dust assumptions, and unique fits. I briefly review the improvements we intend to carry out for our next grid of models, which will eliminate many of these limitations. Finally, I show examples of applications of this tool to massive young stars., Comment: 8 Pages, 3 Figures, to appear in the proceedings for "Massive Star Formation: Observations confront Theory 2007"
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- 2007
203. Spectral Energy Distributions of High Mass Proto Stellar Objects - Evidence for High Accretion Rates
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Fazal, F. M., Sridharan, T. K., Qiu, K., Robitaille, T. P., Whitney, B. A., and Zhang, Q.
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Astrophysics - Abstract
The spectral energy distributions (SEDs), spanning the mid-infrared to millimeter wavelengths, of a sample of 13 high-mass protostellar objects (HMPOs) were studied using a large archive of 2-D axisymmetric radiative transfer models. Measurements from the Spitzer GLIMPSE and MIPSGAL surveys and the MSX survey were used in addition to our own surveys at millimeter and submillimeter wavelengths to construct the SEDs, which were then fit to the archive of models. These models assumed that stars of all masses form via accretion and allowed us to make estimates for the masses, luminosities and envelope accretion rates for the HMPOs. The models fit the observed SEDs well. The implied envelope accretion rates are high, $\approx 10^{-2.5} \msun/yr$, consistent with the accretion-based scenario of massive star formation. With the fitted accretion rates and with mass estimates of up to $\sim 20 \msun$ for these objects, it appears plausible that stars with stellar masses $M_{\ast} > 20 \msun$ can form via accretion., Comment: 10 pages; 3 figures; 3 tables
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- 2007
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204. Infrared point source variability between the Spitzer and MSX surveys of the Galactic mid-plane
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Robitaille, Thomas P., Cohen, Martin, Whitney, Barbara A., Meade, Marilyn, Babler, Brian, Indebetouw, Remy, and Churchwell, Ed
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Astrophysics - Abstract
We present a list of 552 sources with suspected variability, based on a comparison of mid-infrared photometry from the GLIMPSE I and MSX surveys, which were carried out nearly a decade apart. We were careful to address issues such as the difference in resolution and sensitivity between the two surveys, as well as the differences in the spectral responses of the instruments. We selected only sources where the IRAC 8.0 and MSX 8.28 micron fluxes differ by more than a factor of two, in order to minimize contamination from sources where the difference in fluxes at 8 micron is due to a strong 10 micron silicate feature. We present a subset of 40 sources for which additional evidence suggests variability, using 2MASS and MIPSGAL data. Based on a comparison with the variability flags in the IRAS and MSX Point-Source Catalogs we estimate that at least a quarter of the 552 sources, and at least half of the 40 sources are truly variable. In addition, we tentatively confirm the variability of one source using multi-epoch IRAS LRS spectra. We suggest that most of the sources in our list are likely to be Asymptotic Giant Branch stars., Comment: 47 pages, 12 Figures, 3 Tables, accepted for publication in AJ
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- 2007
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205. The Spitzer Survey of the Small Magellanic Cloud: Discovery of Embedded Protostars in the HII Region NGC 346
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Simon, Joshua D., Bolatto, Alberto D., Whitney, Barbara A., Robitaille, Thomas P., Shah, Ronak Y., Makovoz, David, Stanimirovic, Snezana, Barba, Rodolfo H., and Rubio, Monica
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Astrophysics - Abstract
We use Spitzer Space Telescope observations from the Spitzer Survey of the Small Magellanic Cloud (S3MC) to study the young stellar content of N66, the largest and brightest HII region in the SMC. In addition to large numbers of normal stars, we detect a significant population of bright, red infrared sources that we identify as likely to be young stellar objects (YSOs). We use spectral energy distribution (SED) fits to classify objects as ordinary (main sequence or red giant) stars, asymptotic giant branch stars, background galaxies, and YSOs. This represents the first large-scale attempt at blind source classification based on Spitzer SEDs in another galaxy. We firmly identify at least 61 YSOs, with another 50 probable YSOs; only one embedded protostar in the SMC was reported in the literature prior to the S3MC. We present color selection criteria that can be used to identify a relatively clean sample of YSOs with IRAC photometry. Our fitted SEDs indicate that the infrared-bright YSOs in N66 have stellar masses ranging from 2 Msun to 17 Msun, and that approximately half of the objects are Stage II protostars, with the remaining YSOs roughly evenly divided between Stage I and Stage III sources. We find evidence for primordial mass segregation in the HII region, with the most massive YSOs being preferentially closer to the center than lower-mass objects. Despite the low metallicity and dust content of the SMC, the observable properties of the YSOs appear consistent with those in the Milky Way. Although the YSOs are heavily concentrated within the optically bright central region of N66, there is ongoing star formation throughout the complex and we place a lower limit on the star formation rate of 3.2 x 10^-3 Msun/yr over the last ~1 Myr., Comment: 13 pages, 5 figures (3 in color), 2 tables. Accepted for publication in ApJ
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- 2007
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206. Embedded Star Formation in the Eagle Nebula with Spitzer/GLIMPSE
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Indebetouw, R., Robitaille, T. R., Whitney, B. A., Churchwell, E., Babler, B., Meade, M., Watson, C., and Wolfire, M.
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Astrophysics - Abstract
We present new Spitzer photometry of the Eagle Nebula (M16, containing the optical cluster NGC 6611) combined with near-infrared photometry from 2MASS. We use dust radiative transfer models, mid-infrared and near-infrared color-color analysis, and mid-infrared spectral indices to analyze point source spectral energy distributions, select candidate young stellar objects (YSOs), and constrain their mass and evolutionary state. Comparison of the different protostellar selection methods shows that mid-infrared methods are consistent, but as has been known for some time, near-infrared-only analysis misses some young objects. We reveal more than 400 protostellar candidates, including one massive young stellar object (YSO) that has not been previously highlighted. The YSO distribution supports a picture of distributed low-level star formation, with no strong evidence of triggered star formation in the ``pillars''. We confirm the youth of NGC 6611 by a large fraction of infrared-excess sources, and reveal a younger cluster of YSOs in the nearby molecular cloud. Analysis of the YSO clustering properties shows a possible imprint of the molecular cloud's Jeans length. Multiwavelength mid-IR imaging thus allows us to analyze the protostellar population, to measure the dust temperature and column density, and to relate these in a consistent picture of star formation in M16., Comment: 16p preprint - ApJ accepted
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- 2007
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207. Molecular Outflows and a Mid-Infrared Census of the Massive Star-Formation Region Associated with IRAS 18507+0121
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Shepherd, D. S., Povich, M. S., Whitney, B. A., Robitaille, T. P., Nurnberger, D. E. A., Bronfman, L., Stark, D. P., Indebetouw, R., Meade, M. R., and Babler, B. L.
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Astrophysics - Abstract
We have observed the central region of the IR-dark cloud filament associated with IRAS 18507+0121 at millimeter wavelengths in CO(1-0), 13CO(1-0), and C18O(1-0) line emission and with the Spitzer Space Telescope at mid-IR wavelengths. Five massive outflows from two cloud cores were discovered. Three outflows are centered on or near an Ultracompact HII region (G34.4+0.23) while the remaining two outflows originate from the millimeter core G34.4+0.23 MM. Modeling of the SEDs of the mid-IR sources identified 31 young stellar objects in the filament with a combined stellar mass of ~127 +/- 27 Msun. An additional 22 sources were identified as probable cluster members based on the presence of strong 24 micron emission. The total star formation efficiency in the G34.4 cloud filament is estimated to be ~7% while the massive and intermediate mass star formation efficiency in the entire cloud filament is estimated to be roughly 2%. A comparison of the gravitational binding energy with the outflow kinetic energy suggests that the compact core containing G34.4+0.23 MM is being destroyed by its molecular outflows whereas the outflows associated with more massive core surrounding the G34.4 UC HII region are not likely to totally disrupt the cloud. Additionally, a qualitative evaluation of the region appears to suggest that stars in this region may have formed in two stages: first lower mass stars formed and then, a few Myrs later, the more massive stars began to form., Comment: Accepted by ApJ, 46 pages, 12 figures
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- 2007
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208. The morphology of minor axis gaseous outflows in edge-on Seyfert galaxies
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Robitaille, T. P., Rossa, J., Bomans, D. J., and van der Marel, R. P.
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Astrophysics - Abstract
(Abridged) Spiral galaxies often have extended outflows that permeate beyond the region of the disk. Such outflows have been seen both in starburst galaxies, actively star forming galaxies and galaxies with an AGN. In the latter galaxies it is unknown whether the large-scale outflows are driven by star formation activity or purely by the active nucleus. The aim of our investigation is to study the frequency of extended minor-axis outflows in edge-on Seyfert galaxies to investigate the role of the AGN, the circumnuclear environment and star formation activity within the disk regions, and their importance for IGM enrichment on large scales. Narrowband imaging in two different ionizational stages (H-alpha and [OIII]) was performed to attempt a discrimination between processes associated with the active nucleus and those connected to star forming activity within the disk. The H-alpha morphology of the Seyfert galaxies is usually complex, but only in three out of 14 galaxies did we find evidence for minor axis disk outflows. At the sensitivity of our observations [OIII] emission is generally detected only in the nuclear region. Overall, our results show that extraplanar emission of similar brightness and extent as in the previously known cases of NGC3079 and NGC4388 is not common in Seyfert galaxies of otherwise similar properties. Comparison with our previous results shows that for nearby edge-on spiral galaxies star formation may be a more powerful mechanism for producing DIG than AGN activity. While in general AGN activity undoubtedly plays some role in driving minor-axis outflows, this probably requires higher AGN luminosities than are encountered in our small distance-limited sample., Comment: accepted for publication in Astronomy & Astrophysics, 36 pages, 25 figures, 5 tables (Figs. 6-24 and Tables 2 + 5 in the online part), Article with Full resolution images is available at http://www.stsci.edu/~marel/psgzdir/seyfert_outflows.ps.gz
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- 2006
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209. Interpreting Spectral Energy Distributions from Young Stellar Objects. II. Fitting observed SEDs using a large grid of pre-computed models
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Robitaille, Thomas P., Whitney, Barbara A., Indebetouw, Remy, and Wood, Kenneth
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Astrophysics - Abstract
We present a method to analyze the spectral energy distributions (SEDs) of young stellar objects (YSOs). Our approach is to fit data with pre-computed 2-D radiation transfer models spanning a large region of parameter space. This allows us to determine not only a single set of physical parameter values but the entire range of values consistent with the multi-wavelength observations of a given source. In this way we hope to avoid any over-interpretation when modeling a set of data. We have constructed spectral energy distributions from optical to sub-mm wavelengths, including new Spitzer IRAC and MIPS photometry, for 30 young and spatially resolved sources in the Taurus-Auriga star-forming region. We demonstrate fitting model SEDs to these sources, and find that we correctly identify the evolutionary stage and physical parameters found from previous independent studies, such as disk mass, disk accretion rate, and stellar temperature. We also explore how fluxes at various wavelengths help to constrain physical parameters, and show examples of degeneracies that can occur when fitting SEDs. A web-based version of this tool is available to the community at http://www.astro.wisc.edu/protostars ., Comment: 54 pages, 7 figures, 12 tables. Accepted for publication in ApJS. Preprint with full resolution figures available at http://www.astro.wisc.edu/protostars/
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- 2006
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210. The Frequency of Mid-Infrared Excess Sources in Galactic Surveys
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Uzpen, B., Kobulnicky, H. A., Monson, A. J., Pierce, M. J., Clemens, D. P., Backman, D. E., Meade, M. R., Babler, B. L., Indebetouw, R., Whitney, B. A., Watson, C., Wolfire, M. G., Benjamin, R. A., Bracker, S., Bania, T. M., Cohen, M., Cyganowski, C. J., Devine, K. E., Heitsch, F., Jackson, J. M., Mathis, J. S., Mercer, E. P., Povich, M. S., Rho, J., Robitaille, T. P., Sewilo, M., Stolovy, S. R., Watson, D. F., Wolff, M. J., and Churchwell, E.
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Astrophysics - Abstract
We have identified 230 Tycho-2 Spectral Catalog stars that exhibit 8 micron mid-infrared extraphotospheric excesses in the MidCourse Space Experiment (MSX) and Spitzer Space Telescope Galactic Legacy MidPlane Survey Extraordinaire (GLIMPSE) surveys. Of these, 183 are either OB stars earlier than B8 in which the excess plausibly arises from a thermal bremsstrahlung component or evolved stars in which the excess may be explained by an atmospheric dust component. The remaining 47 stars have spectral classifications B8 or later and appear to be main sequence or late pre-main-sequence objects harboring circumstellar disks. Six of the 47 stars exhibit multiple signatures characteristic of pre-main-sequence circumstellar disks, including emission lines, near-infrared K-band excesses, and X-ray emission. Approximately one-third of the remaining 41 sources have emission lines suggesting relative youth. Of the 25 GLIMPSE stars with SST data at >24 microns, 20 also show an excess at 24 microns. Three additional objects have 24 micron upper limits consistent with possible excesses, and two objects have photospheric measurements at 24 microns. Six MSX sources had a measurement at wavelengths >8 microns. We modeled the excesses in 26 stars having two or more measurements in excess of the expected photospheres as single-component blackbodies. We determine probable disk temperatures and fractional infrared luminosities in the range 191 < T < 787 and 3.9x10^-4 < L_IR/L_* < 2.7x10^-1. We estimate a lower limit on the fraction of Tycho-2 Spectral Catalog main-sequence stars having mid-IR, but not near-IR, excesses to be 1.0+-0.3%., Comment: Accepted to ApJ
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- 2006
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211. Interpreting Spectral Energy Distributions from Young Stellar Objects. I. A grid of 200,000 YSO model SEDs
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Robitaille, Thomas P., Whitney, Barbara A., Indebetouw, Remy, Wood, Kenneth, and Denzmore, Pia
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Astrophysics - Abstract
We present a grid of radiation transfer models of axisymmetric young stellar objects (YSOs), covering a wide range of stellar masses (from 0.1Msun to 50Msun) and evolutionary stages (from the early envelope infall stage to the late disk-only stage). The grid consists of 20,000 YSO models, with spectral energy distributions (SEDs) and polarization spectra computed at ten viewing angles for each model, resulting in a total of 200,000 SEDs. [...]. These models are publicly available on a dedicated WWW server: http://www.astro.wisc.edu/protostars/ . In this paper we summarize the main features of our models, as well as the range of parameters explored. [...]. We examine the dependence of the spectral indices of the model SEDs on envelope accretion rate and disk mass. In addition, we show variations of spectral indices with stellar temperature, disk inner radius, and disk flaring power for a subset of disk-only models. We also examine how changing the wavelength range of data used to calculate spectral indices affects their values. We show sample color-color plots of the entire grid as well as simulated clusters at various distances with typical {\it Spitzer Space Telescope} sensitivities. We find that young embedded sources generally occupy a large region of color-color space due to inclination and stellar temperature effects. Disk sources occupy a smaller region of color-color space, but overlap substantially with the region occupied by embedded sources, especially in the near- and mid-IR. We identify regions in color-color space where our models indicate that only sources at a given evolutionary stage should lie. [...]., Comment: 69 pages, 28 figures, Accepted for publication in ApJS. Preprint with full resolution figures available at http://www.astro.wisc.edu/protostars/
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- 2006
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212. Spiral shocks, triggering of star formation and the velocity dispersion in Giant Molecular Clouds
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Bonnell, I. A., Dobbs, C. L., Robitaille, T. R., and Pringle, J. E.
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Astrophysics - Abstract
We present numerical simulations of the passage of clumpy gas through a galactic spiral shock and the subsequent formation of giant molecular clouds (GMCs). The spiral shock forms dense clouds while dissipating kinetic energy, producing regions that are locally gravitationally bound and collapse to form stars. The effect of the clumpiness of gas as it passes through the shock is to generate chaotic internal motions in the gas. The kinematics of these motions are found to agree with the observed velocity-dispersion/size relation found in star-forming regions. In contrast to the standard picture where continuously driven turbulence generates the density inhomogeneities in star-forming clouds, we find here that it is the clumpiness of the interstellar gas that produces the chaotic motions as it passes through the spiral shock and initiates the star formation process. The velocity dispersion can be understood as being due to the random mass loading of clumps as they converge in the spiral shock. In this model there is no need for any internal or external continuous driving mechanism for the 'turbulence'. The coupling of the clouds' internal kinematics to their externally triggered formation removes the need for the clouds to be self-gravitating. Indeed, while clearly some parts of the clouds are self-gravitating and able to form stars, most of the molecular material remains gravitationally unbound. This can provide a simple explanation for the low efficiency of star formation., Comment: 9 pages, 6 figures, accepted for publication in MNRAS
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- 2005
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213. An Analysis of Universality in Blackbody Radiation
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Robitaille, Pierre-Marie
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Physics - General Physics - Abstract
Through the formulation of his law of thermal emission, Kirchhoff conferred upon blackbody radiation the quality of universality [G.Kirchhoff, Annalen der Physik 109, 275 (1860)]. Consequently, modern physics holds that such radiation is independent of the nature and shape of the emitted object. Recently, Kirchhoff's experimental work and theoretical conclusions have been reconsidered [P.M.L. Robitaille, IEEE Transactions on Plasma Science 31(6), 1263 (2003). In this work, Einstein's derivation of the Planckian relation is reexamined. It is demonstrated that claims of universality in blackbody radiation are invalid., Comment: Presented at the New England Section Meeting of the APS on April 2, 2005 at MIT
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- 2005
214. 2-D and 3-D Radiation Transfer Models of High-Mass Star Formation
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Whitney, Barbara A., Robitaille, Thomas P., Indebetouw, Remy, Wood, Kenneth, Bjorkman, J. E., and Denzmore, Pia
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Astrophysics - Abstract
2-D and 3-D radiation transfer models of forming stars generally produce bluer 1-10 micron colors than 1-D models of the same evolutionary state and envelope mass. Therefore, 1-D models of the shortwave radiation will generally estimate a lower envelope mass and later evolutionary state than multidimensional models. 1-D models are probably reasonable for very young sources, or longwave analysis (wavelengths > 100 microns). In our 3-D models of high-mass stars in clumpy molecular clouds, we find no correlation between the depth of the 10 micron silicate feature and the longwave (> 100 micron) SED (which sets the envelope mass), even when the average optical extinction of the envelope is >100 magnitudes. This is in agreement with the observations of Faison et al. (1998) of several UltraCompact HII (UCHII) regions, suggesting that many of these sources are more evolved than embedded protostars. We have calculated a large grid of 2-D models and find substantial overlap between different evolutionary states in the mid-IR color-color diagrams. We have developed a model fitter to work in conjunction with the grid to analyze large datasets. This grid and fitter will be expanded and tested in 2005 and released to the public in 2006., Comment: 10 pages, 8 figures, to appear in the proceedings of IAU Symp 227, Massive Star Birth: A Crossroads of Astrophysics, (Cesaroni R., Churchwell E., Felli M., Walmsley C. editors)
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- 2005
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215. A High Temperature Liquid Plasma Model of the Sun
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Robitaille, Pierre-Marie
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Astrophysics - Abstract
In this work, a liquid model of the Sun is presented wherein the entire solar mass is viewed as a high density/high energy plasma. This model challenges our current understanding of the densities associated with the internal layers of the Sun, advocating a relatively constant density, almost independent of radial position. The incompressible nature of liquids is advanced to prevent solar collapse from gravitational forces. The liquid plasma model of the Sun is a non-equilibrium approach, where nuclear reactions are free to occur throughout the solar mass. The primary means of addressing internal heat transfer are convection and conduction. As a result of the convective processes on the solar surface, the liquid model brings into question the established temperature of the solar photosphere by highlighting a violation of Kirchhoff's law of thermal emission. Along these lines, the model emphasizes that radiative emission is a surface phenomenon. Strong evidence is provided that the Sun is a high density/high energy liquid plasma. This evidence is based on our knowledge of Planckian thermal emission and condensed matter, including the existence of pressure ionization and liquid metallic hydrogen at high temperatures and pressures. The equations of magnetohydrodynamics are invoked as the proper vehicle for the understanding od stellar convection and structure. Prior to introducing the liquid plasma model, the historic and scientific justifications for the gaseous model of the Sun are reviewed and the gaseous equations of state are also discussed., Comment: corrected typos in abstract
- Published
- 2004
216. Une encyclopédie de la pensée moderne : Les collections anciennes de l’Université du Québec à trois-Rivières
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Audy-Trottier, Andréane, Dion, Nicholas, Francès, Cyril, Gladu, Kim, Bernier, André, Robitaille, Isabelle, Audy-Trottier, Andréane, Dion, Nicholas, Francès, Cyril, Gladu, Kim, Bernier, André, and Robitaille, Isabelle
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- 2022
217. Bilan du gouvernement de la CAQ. Entre nationalisme et pandémie : Entre nationalisme et pandémie
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Birch, Lisa, Dufresne, Yannick, Duval, Dominic, Tremblay-Antoine, Camille, Robitaille, Antoine, Préface d’, Birch, Lisa, Dufresne, Yannick, Duval, Dominic, Tremblay-Antoine, Camille, and Robitaille, Antoine
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- 2022
218. The Structure of Brown Dwarf Circumstellar Disks
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Walker, Christina, Wood, Kenneth, Lada, C. J., Robitaille, Thomas, Bjorkman, J. E., and Whitney, Barbara
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Astrophysics - Abstract
We present synthetic spectra for circumstellar disks that are heated by radiation from a central brown dwarf. Under the assumption of vertical hydrostatic equilibrium, our models yield scaleheights for brown dwarf disks in excess of three times those derived for classical T Tauri (CTTS) disks. If the near-IR excess emission observed from brown dwarfs is indeed due to circumstellar disks, then the large scaleheights we find could have a significant impact on the optical and near-IR detectability of such systems. Our radiation transfer calculations show that such highly flared disks around brown dwarfs will result in a large fraction of obscured sources due to extinction of direct starlight by the disk over a wide range of sightlines. The obscured fraction for a 'typical' CTTS is less than 20%. We show that the obscured fraction for brown dwarfs may be double that for CTTS, but this depends on stellar and disk mass. We also comment on possible confusion in identifying brown dwarfs via color-magnitude diagrams: edge-on CTTS display similar colors and magnitudes as a face-on brown dwarf plus disk systems., Comment: 13 pages, 13 figures, accepted for publication in MNRAS
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- 2004
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219. A mobile device application (app) to improve adherence to an enhanced recovery program for colorectal surgery: a randomized controlled trial
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Mata, Juan, Pecorelli, Nicolò, Kaneva, Pepa, Moldoveanu, Dan, Gosselin-Tardiff, Alexandre, Alhashemi, Mohsen, Robitaille, Stephan, Balvardi, Saba, Lee, Lawrence, Stein, Barry L., Liberman, Sender, Charlebois, Patrick, Fiore, Jr., Julio F., and Feldman, Liane S.
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- 2020
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220. The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis
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Bose, Poulomee, Tremblay, Elsa, Maios, Claudia, Narasimhan, Vijay, Armstrong, Gary A. B., Liao, Meijiang, Parker, J. Alex, Robitaille, Richard, Wen, Xiao Yan, Barden, Christopher, and Drapeau, Pierre
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- 2019
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221. Associations between fruit and vegetables intake and abnormal glucose tolerance among women with prior gestational diabetes mellitus
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Mercier, Roxanne, Perron, Julie, Weisnagel, S. John, and Robitaille, Julie
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- 2019
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222. Ferrofluid Based Deformable Mirrors - a New Approach to Adaptive Optics Using Liquid Mirrors
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Laird, P., Bergamasco, R., Berube, V., Borra, E. F., Ritcey, A., Rioux, M., Robitaille, N., Thibault, S., Silva Jr, L. Vieira da, and Yockell-Lelievre, H.
- Subjects
Astrophysics - Abstract
The trend towards ever larger telescopes and more advanced adaptive optics systems is driving the need for deformable mirrors with a large number of low cost actuators. Liquid mirrors have long been recognized a potential low cost alternative to conventional solid mirrors. By using a water or oil based ferrofluid we are able to benefit from a stronger magnetic response than is found in magnetic liquid metal amalgams and avoid the difficulty of passing a uniform current through a liquid. Depositing a thin silver colloid known as a metal liquid-like film (MELLF) on the ferrofluid surface solves the problem of low reflectivity of pure ferrofluids. This combination provides a liquid optical surface that can be precisely shaped in a magnetic field. We present experimental results obtained with a prototype deformable liquid mirror based on this combination., Comment: 9 pages. To appear in SPIE meeting in Hawaii August 2002. Astronomical Telescopes and Instrumentation
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- 2002
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223. Hypoxia-inducible Factor-1 Activation in Nonhypoxic Conditions: The Essential Role of Mitochondrial-derived Reactive Oxygen Species
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Patten, David A, Lafleur, Véronique N, Robitaille, Geneviève A, Chan, Denise A, Giaccia, Amato J, and Richard, Darren E
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Genetics ,Cardiovascular ,Generic health relevance ,Angiotensin II ,Animals ,Anti-Bacterial Agents ,Antifungal Agents ,Cells ,Cultured ,Electron Transport Complex III ,Hypoxia-Inducible Factor 1 ,Male ,Methacrylates ,Mitochondria ,Mitogen-Activated Protein Kinase 1 ,Mitogen-Activated Protein Kinase 3 ,Muscle ,Smooth ,Vascular ,Myocytes ,Smooth Muscle ,NADPH Oxidases ,Polyenes ,RNA ,Small Interfering ,Rats ,Rats ,Wistar ,Reactive Oxygen Species ,Thiazoles ,Biological Sciences ,Medical and Health Sciences ,Developmental Biology - Abstract
Hypoxia-inducible factor-1 (HIF-1) is a key transcription factor for responses to low oxygen. Different nonhypoxic stimuli, including hormones and growth factors, are also important HIF-1 activators in the vasculature. Angiotensin II (Ang II), the main effecter hormone in the renin-angiotensin system, is a potent HIF-1 activator in vascular smooth muscle cells (VSMCs). HIF-1 activation by Ang II involves intricate mechanisms of HIF-1α transcription, translation, and protein stabilization. Additionally, the generation of reactive oxygen species (ROS) is essential for HIF-1 activation during Ang II treatment. However, the role of the different VSMC ROS generators in HIF-1 activation by Ang II remains unclear. This work aims at elucidating this question. Surprisingly, repression of NADPH oxidase-generated ROS, using Vas2870, a specific inhibitor or a p22(phox) siRNA had no significant effect on HIF-1 accumulation by Ang II. In contrast, repression of mitochondrial-generated ROS, by complex III inhibition, by Rieske Fe-S protein siRNA, or by the mitochondrial-targeted antioxidant SkQ1, strikingly blocked HIF-1 accumulation. Furthermore, inhibition of mitochondrial-generated ROS abolished HIF-1α protein stability, HIF-1-dependent transcription and VSMC migration by Ang II. A large number of studies implicate NADPH oxidase-generated ROS in Ang II-mediated signaling pathways in VSMCs. However, our work points to mitochondrial-generated ROS as essential intermediates for HIF-1 activation in nonhypoxic conditions.
- Published
- 2010
224. Semaglutide and cardiovascular outcomes in patients with obesity and prevalent heart failure: a prespecified analysis of the SELECT trial
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Deanfield, John, Verma, Subodh, Scirica, Benjamin M, Kahn, Steven E, Emerson, Scott S, Ryan, Donna, Lingvay, Ildiko, Colhoun, Helen M, Plutzky, Jorge, Kosiborod, Mikhail N, Hovingh, G Kees, Hardt-Lindberg, Søren, Frenkel, Ofir, Weeke, Peter E, Rasmussen, Søren, Goudev, Assen, Lang, Chim C, Urina-Triana, Miguel, Pietilä, Mikko, Lincoff, A Michael, Abe, Mitsunori, Abhaichand, Rajpal K, Abhayaratna, Walter P, Abhyankar, Atul, Abidin, Imran B Zainal, Abou Assi, Hiba, Accini Mendoza, Jose L, Adas, Mine, Agaiby, John M, Agarwal, Devendra K, Agha, Maher, Ahmed, Azazuddin, Ahtiainen, Petteri, Aigner, Elmar, Ajay, Naik, Ali, Norsiah, Al-Karadsheh, Amer, Allison, Roy, Allison, Dale C, Alpenidze, Diana, Altuntas, Yuksel, Al-Zoebi, Ayham, Ambuj, Roy, Amerena, John, Anderson, Robert J, Ando, Toshiaki, Andrews, Robert, Antonova, Elizaveta, Appel, Karl-Friedrich, Arantes, Flávia B, Araz, Mustafa, Arbel, Yaron, Arenas León, José L, Argyrakopoulou, Georgia, Ariani, Mehrdad, Arias Mendoza, Maria A, Arif, Ahmed A, Arneja, Jaspal, Aroda, Vanita R, Aronne, Louis J, Arstall, Margaret, Asamoah, Njaimeh, Asanin, Milika, Audish, Hanid, Avram, Rodica, Badat, Aysha, Badiu, Corin V, Bakdash, Wa'el, Bakiner, Okan S, Bandezi, Vuyokazi N, Bang, Liew H, Bansal, Sandeep, Baranyai, Marietta, Barbarash, Olga, Barber, Mark, Barnum, Otis, Barone Rochette, Gilles, Bashkin, Amir, Baum, Seth, Bays, Harold E, Bazzoni Ruiz, Alberto E, Beckowski, Maciej, Beerachee, Yaswin, Bellary, Srikanth, Belousova, Lidia, Berk, Martin, Bernstein, Marc, Berra, Cesare, Beshay, Isaac, Bhagwat, Ajit, Bhan, Arti, Biggs, William C, Billings, Liana, Bitar, Fahed, Block, Bradley, Bo, Simona, Bogdanski, Pawel, Bolshakova, Olga O, Boshchenko, Alla A, Bosworth, Hayden, Botero Lopez, Rodrigo, Bôttcher, Morten, Bourgeois, Ronald, Brautigam, Donald, Breton, Cristian F, Broadley, Andrew, Brockmyre, Andrew P, Brodie, Steven K, Bucci, Marco, Budincevic, Hrvoje, Budoff, Matthew J, Buffman, Barry, Buljubasic, Nediljka, Buranapin, Supawan, Burgess, Lesley, Burguera, Bartolomé, Buriakovska, Olena, Buscemi, Silvio, Busch, Robert, Buse, John B, Buynak, Robert, Byrne, Maria, Caceaune, Elena, Cadena Bonfanti, Alberto J, Calinescu, Cornell V, Call, Robert S, Canecki Varzic, Silvija, Cannon, Kevin, Capehorn, Matt, Cariou, Bertrand, Carr, Jeffrey, Carrillo-Jimenez, Rodolfo, Casas, Marcelo, Castro, Almudena, Celik, Ahmet, Cercato, Cintia, Cermak, Ondrej, Cha, James Y, Chacon, Carolina, Chaicha-Brom, Tira, Chandra, Sandeep, Chettibi, Mohamed, Chevts, Julia, Christopher, Johann, Chrustowski, Witold, Cif, Adriana, Clark, Rebecca, Clark, Wayne, Clifford, Piers, Coetzee, Kathleen, Cogni, Giulia, Colao, Anna Maria, Colquhoun, David M, Concha, Mauricio, Condit, Jonathan, Constance, Christian, Constantin, Ciprian, Constantinescu, Silviana, Corbett, Clive, Cornett, George M, Correia, Marcelo, Cortinovis, Fiorenzo, Cosma, Dana, Creely, Steven, Cross, David, Curtis, Brian, Czochra, Wojciech, Daboul, Nizar Y, Dagdelen, Selcuk, D'agostino, Ronald, Dang, Cuong, Datta, Sudip, Davuluri, Ashwini K, Dawood, Saleem Y, De Jong, Douwe M, De La Cuesta, Carmen, De Los Rios Ibarra, Manuel O, De Pablo, Carmen, De Pauw, Michel, Dela Llana, Alexander, Delibasic, Maja, Delic-Brkljacic, Diana, Demicheli, Thibaud, Denger, Ralf J, Desai, Devang, Desai, Piyush, Desouza, Cyrus V, Dicker, Dror, Djenic, Nemanja, Dobson, Simon, Doi, Masayuki, Doran, Jesse A, Dorman, Reinhart, Dotta, Francesco, Dukes, Carl E, Duronto, Ernesto, Durst, Ronen, Dvoryashina, Irina V, Ebrahim, Iftikhar O, Eggebrecht, Holger, Egstrup, Kenneth, Ekinci, Elif I, Eliasson, Björn, Eliasson, Ken, Enache, Georgiana, Enculescu, Dan, English, Patrick, Ermakova, Polina, Ershova, Olga, Ezaki, Hirotaka, Ezhov, Marat, Farias, Eduardo, Farias, Javier M, Farsky, Pedro S, Ferreira, Daniel, Filteau, Pierre, Finneran, Matthew P, Folkens, Eric M, Fonseca, Alberto G, Fonseca, Luisa, Fordan, Steven, Fourie, Nyda, França, Sara, Franco, Denise R, Franek, Edward, Friedman, Keith, Frittitta, Lucia, Froer, Michael, Fuckar, Krunoslav, Fujii, Kenshi, Fujita, Ryoko, Fukushima, Yasushi, Fulat, Mohamed, Fulwani, Mahesh, Gajos, Grzegorz, Galyavich, Albert, Gambill, Michael L, Gandotra, Dheeraj, Winston, Gandy, Garcia Hernandez, Pedro A, García Reza, Raymundo, Garg, Naveen, Garg, Sandeep, Garvey, William T, Garza, Juan C, Gatta-Cherifi, Blandine, Gelev, Valeri, Geller, Steven A, Geohas, Jeffrey G, Georgiev, Borislav, Ghazi, Adline, Gilbert, Matthew P, Gilinskaya, Olga, Gislason, Gunnar, Gogas Yavuz, Dilek, González Albarrán, Olga, Gordeev, Ivan G, Gorton, Sidney C, Goudev, Assen, Gretland Valderhaug, Tone, Groenemeijer, Bjorn, Gul, Ibrahim, Gullestad, Lars, Gurieva, Irina, Guseva, Galina N, Hagenow, Andreas, Haluzik, Martin, Halvorsen, Sigrun, Hammoudi, Naima, Hanaoka, Keiichi, Hancu, Nicolae, Hanusch, Ursula, Harris, Kathleen, Harris, Barry, Hartleib, Michael, Hartman, Aaron N, Hata, Yoshiki, Heimer, Brian, Herman, Lee, Herzog, William, Hewitt, Eric, Heymer, Peter, Hiremath, Shirish, Hjelmesaeth, Joeran, Høgalmen, Rasmus Geir, Høivik, Hans Olav, Holmer, Helene, Horoshko, Olha, Houser, Patricia M, Hove, Jens D, Hsieh, I-Chang, Hulot, Jean-Sébastien, Hussein, Zanariah, Ilashchuk, Tetiana, Ilveskoski, Erkki, Ipatko, Irina, Iranmanesh, Ali, Isawa, Tsuyoshi, Issa, Moises, Iteld, Bruce, Iwasawa, Takamasa, Jabbar, Danish, Jackson, Richard A, Jackson-Voyzey, Ewart, Jacob, Stephan, Jaffrani, Naseem A, Jardula, Michael F, Jastreboff, Ania, Jensen, Svend E, Jerkins, Terri, Jimenez-Ramos, Silvia A, Jitendra Pal Singh, Sawhney, Johnson, Wallace, Joyce, John M, Jozefowska, Malgorzata, Jugnundan, Prakash, Jungmair, Wolfgang, Jurowiecki, Jaroslaw, Kadokami, Toshiaki, Kahali, Dhiman, Kahrmann, Gerd, Kaiser, Sergio E, Kalmucki, Piotr, Kanadasi, Mehmet, Kandath, David, Kania, Grzegorz, Kannan, J, Kapp, Cornelia, Karczmarczyk, Agnieszka, Kartalis, Athanasios, Kaser, Susanne, Kasim, Sazzli Shahlan, Kastelic, Richard, Kato, Toshiaki, Katova, Tzvetana, Kaul, Upendra, Kautzky-Willer, Alexandra, Kawanishi, Masahiro, Kayikcioglu, Meral, Kazakova, Elena E, Keeling, Philip, Kempe, Hans-Peter, Kereiakes, Dean J, Kerneis, Mathieu, Keski-Opas, Tiina, Khadra, Suhail, Khaisheva, Larisa, Kharakhulakh, Marina, Khlevchuk, Tatiana, Khoo, Jeffrey, Kiatchoosakun, Songsak, Kinoshita, Noriyuki, Kinoshita, Masaharu, Kitamura, Ryoji, Kiyosue, Arihiro, Klavina, Irina, Klein, Eric J, Klimsa, Zdenek, Klonoff, David, Klug, Eric, Kobalava, Zhanna, Kodera, Satoshi, Koga, Tokushi, Kokkinos, Alexander, Koleckar, Pavel, Könyves, László, Koren, Michael J, Kormann, Adrian P, Kostner, Karam, Kreutzmann, Kristin, Krishinan, Saravanan, Krishnasamy, Sathya S, Krivosheeva, Inga, Kruljac, Ivan, Kubicki, Ted, Kuchar, Ladislav, Kujawiak, Monika, Kunishige, Hideyuki, Kurtinecz, Melinda, Kurtz Lisboa, Hugo R, Kushnir, Mykola, Kyyak, Yulian, Lace, Arija, Lakka, Timo, Lalic, Nebojsa, Lalic, Katarina, Lambadiari, Vaia, Lanaras, Leonidas, Lang, Chim, Langlois, Marie-France, Lash, Joseph, Latkovskis, Gustavs, Lau, David, Lazcano Soto, José Roberto, Le Roux, Carel, Ledesma, Gilbert N, Lee, Li Yuan, Lee, Thung-Lip, Lee, Kelvin, Lehrke, Michael, Leite, Silmara O, Leksycka, Agata, Lenzmeier, Thomas, Leonetti, Frida, Leonidova, Viktoriia, Lepor, Norman, Leung, Melissa, Levchenko, Olena, Levins, Peter, Levy, Louis J, Lewis, Matthew, Liberopoulos, Evangelos, Liberty, Idit, Lindholm, Carl-Johan, Lingvay, Ildiko, Linhart, Ales, Liu, Ming-En, Liu, Jenny, Lofton, Holly, Logemann, Timothy, Lombaard, Johannes J, Lombard, Landman, Lorraine, Richard, Lovell, Charles F, Ludvik, Bernhard, Lukaszewicz, Monika, Lupkovics, Géza, Lupovitch, Steven, Lupu, Sirona, Lynch, Mary, Lysak, Zoreslava, Lysenko, Tatyana A, Maeda, Hajime, Maeda, Itaru, Mæng, Michael, Mahajan, Ajay U, Maher, Vincent, Maia, Lilia N, Makotoko, Ellen M, Malavazos, Alexis, Malecha, Jan, Malicherova, Emilia, Manita, Mamoru, Mannucci, Edoardo, Mareev, Viacheslav, Marin, Liliana, Markova, Tatiana, Marso, Steven P, Martens, F.M.A.C., Martinez, Cuper, Martinez Cano, Carlos A, Martins, Cristina, Masmiquel Comas, Luis, Matsumoto, Takashi, Mcdonald, Kenneth, Mcgowan, Barbara, Mcgrew, Frank, Mclean, Barry K, Mcpherson, David D, Merino Torres, Juan Francisco, Meyers, Peter, Meyhöfer, Sebastian, Mezquita Raya, Pedro, Milanova, Maria, Milicic, Davor, Miller, Gary, Mills, Richard E, Mîndrescu, Nicoleta M, Mingrone, Geltrude, Minkova, Dotska A, Mirani, Marco, Miras, Alexander, Mistodie, Cristina V, Mitomo, Satoru, Mittal, Sanjay, Miyake, Taiji, Miyamoto, Naomasa, Molony, David, Monteiro, Pedro, Mooe, Thomas, Moosa, Naeem, Morales Portillo, Cristobal, Morales Villegas, Enrique C, Morawski, Emily J, Morbey, Claire, Morin, Robert P, Morisaki, Kuniaki, Morosanu, Magdalena, Mosenzon, Ofri, Mostovoy, Yuriy, Munir, Iqbal, Muratori, Fabrizio, Murray, Ryan, Murthy, Avinash, Myint, Min, Myshanych, Galyna, Nafornita, Valerica, Nagano, Takuya, Nair, Sunil, Nakhle, Samer N, Natsuaki, Masahiro, Nayak, Bindu M, Nibouche, Djamel Eddine, Nicholls, Stephen, Nicolau, José C, Nicolescu, Georgiana, Nierop, Peter, Niskanen, Leo, Ntaios, George, Nygård, Ottar Kjell, Oaks, Joshua B, Obrezan, Andrey, O'donnell, Philip, Oguri, Mitsutoshi, Oguzhan, Abdurrahman, Oh, Fumiki, Ohsugi, Mitsuru, Okada, Yoshio, Okayama, Hideki, Onaca, Adriana, Onaka, Haruhiko, Oneil, Patrick, Ong, Tiong Kiam, Ong, Stephen, Ono, Yasuhiro, Opsahl, Paul J, Ostrowska, Lucyna, Oviedo, Alejandra, Ozdogan, Oner, Ozpelit, Ebru, Pagkalos, Emmanouil, Pagotto, Uberto, Páll, Dénes, Pandey, Amritanshu- Shekhar, Parkhomenko, Oleksandr, Parvathareddy, Krishna Malakondareddy, Patel, Minesh B, Patsilinakos, Sotirios, Paul, Neil, Pedersen, Sue, Pereira, Isabel, Pereira, Edward Scott, Perez Terns, Paula, Perez-Vargas, Elba A, Pergaeva, Yulia, Perkelvald, Alexander, Peskov, Andrey B, Peter, Jonathan, Peters, Karina, Petit, Catherine, Petrov, Ivo, Philis-Tsimikas, Athena, Pietilä, Mikko, Pinto, Fausto, Piros, Annamária, Piyayotai, Dilok, Platonov, Dmitriy, Poirier, Paul, Pop, Lavinia, Popa, Bogdan, Pop-Busui, Rodica, Poremba, John, Porto, Alejandro, Postadzhiyan, Arman, Pothineni, Ramesh B, Potu, Ranganatha P, Powell, Talessa, Prafulla, Kerkar G, Prager, Rudolf, Prakova-Teneva, Zhulieta R, Pratley, Richard E, Price, Hermione, Pulka, Grazyna, Pullman, John, Punt, Zelda E, Purighalla, Raman S, Purnell, Peter, Qureshi, Mansoor, Rabasa-Lhoret, Remi, Raikhel, Marina A, Rancane, Gita, Randeva, Harpal, Rasouli, Neda, Reurean Pintilei, Delia V, Reyes, Ciro R, Rezgale, Inga, Rice, Eva, Riley, Thaddeus H, Risser, Joseph A, Ristic, Arsen, Rivas Fernández, Margarita, Robbins, David, Robitaille, Yves, Rodbard, Helena W, Rodriguez Plazas, Jaime A, Römer, T.J., Rosen, Glenn, Rosman, Dr Azhari, Rossi, Paulo, Rudenko, Leonid, Ruffin, Omari, Ruhani, Anwar Irawan, Runev, Nikolay, Ruyatkin, Dmitriy, Ruzic, Alen, Ryabov, Vyacheslav V, Rydén, Lars, Saggar, Suraj, Sakamoto, Tomohiro, Salter, Tim, Samal, Aditya K, Samoilova, Yulia, Sanabria, Hugo D, Sancak, Seda, Sangrigoli, Renee, Sansanayudh, Nakarin, Santini, Ferruccio, Saraiva, José F, Sardinov, Ruslan, Sargeant, William, Sari, Ramazan, Sathananthan, Airani, Sathyapalan, Thozhukat, Sato, Atsushi, Sauter, Joachim, Sbraccia, Paolo, Schaap, J., Schaum, Thomas, Schiele, François, Scott, John, Segal Lieberman, Gabriella, Segner, Alexander, Senior, Roxy, Sergeeva-Kondrachenko, Marina Y, Serota, Harvey, Serusclat, Pierre, Sethi, Rishi, Shah, Manoj K, Shah, Neerav, Shalaev, Sergey, Sharma, Raj, Sharma, Sumeet, Shaydyuk, Oksana, Shea, Heidi C, Shechter, Michael, Shehadeh, Naim, Shirazi, Mitra, Shlesinger, Yshay, Shneker, Ayham, Shutemova, Elena, Siasos, Gerasimos, Siddiqui, Imran A, Sidey, Jennifer, Sigal, Felix, Sime, Iveta, Singh, Narendra, Siraj, Elias, Sivalingam, Kanagaratnam, Skoczylas, Grzegorz, Smith, Stephen K, Smolenskaya, Olga, Snyder, Brian, Sofer, Yael, Sofley, C.W., Solano, Royce, Sonmez, Yusuf A, Sorokin, Maxim, Soto González, Alfonso, Sotolongo, Carlos, Soufer, Joseph, Soyluk Selcukbiricik, Ozlem, Spaic, Tamara, Spriggs, Douglas, Sreenan, Seamus, Stahl, Hans-Detlev, Stamatelopoulos, Kimon, Stanislavchuk, Mykola, Stankovic, Goran, Stasek, Josef, Steg, Gabriel, Steindorf, Joerg, Stephan, Dominique, Stewart, John, Still, Christopher, St-Maurice, Francois, Stogowska-Nikiciuk, Barbara, Stoker, Jeff, Stokic, Edita, Strzelecka, Anna, Sturm, Kerstin, Sueyoshi, Atsushi, Sugiura, Toshiyuki, Sultan, Senan, Suplotova, Lyudmila A, Suwanagool, Arisara, Suwanwalaikorn, Sompongse, Sveklina, Tatiana, Swanson, Neil, Swart, Henk, Swenson, Bradley P, Szyprowska, Ewa, Tait, Graeme, Takács, Róbert, Takeuchi, Yuzo, Tamirisa, Aparna, Tanaka, Hideki, Tatovic, Danijela, Tellier, Guy, Teragawa, Hiroki, Teterovska, Dace, Thomas, Nihal, Thuan, Jean-Francois, Tinahones, Francisco, Tisheva-Gospodinova, Snezhanka, Toarba, Cristina, Todoriuk, Liudmyla, Tokmakova, Mariya, Tonstad, Serena, Toplak, Hermann, Tran, Henry, Tripathy, Devjit, Trusau, Aliaksandr, Tsabedze, Nqoba, Tsougos, Elias, Tsoukas, George M, Tuccinardi, Dario, Tuna, Mazhar M, Turatti, Luiz A, Tziomalos, Konstantinos, Udommongkol, Chesda, Ueda, Osamu, Ukkola, Olavi, Unubol, Mustafa, Urbach, Dorothea, Urina Triana, Miguel A, Usdan, Lisa, Vaidya, Bijay, Vale, Noah, Vallieres, Gerald, Van Beek, Andre P, Van De Borne, Philippe, Van Der Walt, Eugene, Van Der Zwaan, C., Van Nieuwenhuizen, Elane, Van Zyl, Louis, Vanduynhoven, Philippe, Varghese, Kiron, Vasileva, Svetla P, Vassilev, Dobrin, Vathesatogkit, Prin, Velychko, Valentyna, Vercammen, Chris, Verges, Bruno, Verma, Subodh, Verwerft, Jan, Vesela, Alica, Veselovskaya, Nadezhda G, Vettor, Roberto, Veze, Irina, Vijan, Vinod, Vijayaraghavan, Ram, Villarino, Adriana, Vincent, Royce, Vinogradova, Oksana, Vishlitzky, Victor, Vlad, Adrian, Vladu, Ionela Mihaela, Vo, Anthony, Von Engelhardt, Charlotte, Von Münchhausen, Candy, Vorobyeva, Olga, Vossenberg, T., Vrolix, Mathias, Vukicevic, Marjana, Vyshnyvetskyy, Ivan, Wadvalla, Shahid, Wagner, Jan, Wakeling, John, Wallace, James, Wan Mohamed, Wan Mohd Izani, Wander, Gurpreet S, Ward, Kathleen, Warren, Mark L, Watanabe, Atsuyuki, Weber, Bruce, Weintraub, Howard, Weisnagel, John, Welker, James, Wendisch, Ulrich, Wenocur, Howard S, Wierum, Craig, Wilding, John, William, Maged, Wilson, Pete, Wilson, Jonathan P, Wong, Yuk-Ki, Wongcharoen, Wanwarang, Wozniak, Iwona, Wu, Chau-Chung, Wyatt, Nell, Wynne, Alan, Yamaguchi, Hiroshi, Yamasaki, Masahiro, Yazici, Dilek, Yeh, Hung-I, Yotov, Yoto, Yuan, Qingyang, Zacher, Jeffrey, Zagrebelnaya, Olga, Zaidman, Cesar J, Zalevskaya, Alsu, Zarich, Stuart, Zatelli, Maria Chiara, Zeller, Helga, Zhdanova, Elena A, Zornitzki, Taiba, Zrazhevskiy, Konstantin, Zykov, Mikhail, Lincoff, A Michael, Ryan, Donna H, Colhoun, Helen M, Deanfield, John E, Emerson, Scott S, Kahn, Steven E, Kushner, Robert F, Plutzky, Jorge, Brown-Frandsen, Kirstine, Hovingh, G Kees, Hardt-Lindberg, Soren, and Tornøe, Christoffer W
- Abstract
Semaglutide, a GLP-1 receptor agonist, reduces the risk of major adverse cardiovascular events (MACE) in people with overweight or obesity, but the effects of this drug on outcomes in patients with atherosclerotic cardiovascular disease and heart failure are unknown. We report a prespecified analysis of the effect of once-weekly subcutaneous semaglutide 2·4 mg on ischaemic and heart failure cardiovascular outcomes. We aimed to investigate if semaglutide was beneficial in patients with atherosclerotic cardiovascular disease with a history of heart failure compared with placebo; if there was a difference in outcome in patients designated as having heart failure with preserved ejection fraction compared with heart failure with reduced ejection fraction; and if the efficacy and safety of semaglutide in patients with heart failure was related to baseline characteristics or subtype of heart failure.
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- 2024
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225. The Value of Strength as a Predictor of Musculoskeletal Injury in Canadian Armed Forces Basic Infantry Candidates
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Robitaille, Eric, Reilly, Tara, Heipel, Scott, Buttici, Hollie, Chasse, Etienne, and Tingelstad, Hans Christian
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- 2024
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226. Enumeration of symmetry classes of convex polyominoes in the square lattice
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Leroux, Pierre, Rassart, Etienne, and Robitaille, Ariane
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Mathematics - Combinatorics ,05B50 (Primary) 05A30, 05A15, 82B41 (Secondary) - Abstract
This paper concerns the enumeration of rotation-type and congruence-type convex polyominoes on the square lattice. These can be defined as orbits of the groups C4, of rotations, and D4, of symmetries of the square acting on (translation- type) polyominoes. In virtue of Burnside's Lemma, it is sufficient to enumerate the various symmetry classes (fixed points) of polyominoes defined by the elements of C4 and D4. Using the Temperley--Bousquet-Melou methodology, we solve this problem and provide explicit or recursive formulas for their generating functions according to width, height and area. We also enumerate the class of asymmetric convex polyominoes, using Moebius inversion, and prove that their number is asymptotically equivalent to the number of convex polyominoes, a fact which is empirically evident., Comment: LaTeX 2e, 31 pages with 22 figures. Accepted in Advances in Applied Mathematics
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- 1998
227. SARS‐CoV‐2 outbreak investigation in a German meat processing plant
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Günther, Thomas, Czech‐Sioli, Manja, Indenbirken, Daniela, Robitaille, Alexis, Tenhaken, Peter, Exner, Martin, Ottinger, Matthias, Fischer, Nicole, Grundhoff, Adam, and Brinkmann, Melanie M
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- 2020
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228. Recruitment and retention of mothers of preschoolers and school-aged children in a social media-delivered healthy eating intervention: lessons learned from a randomized controlled trial
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Dumas, Audrée-Anne, Lemieux, Simone, Lapointe, Annie, Provencher, Véronique, Robitaille, Julie, and Desroches, Sophie
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- 2020
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229. Mechanisms of cell damage due to mechanical impact: an in vitro investigation
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Kang, Wonmo, Robitaille, Michael C., Merrill, Marriner, Teferra, Kirubel, Kim, Chunghwan, and Raphael, Marc P.
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- 2020
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230. PVAmpliconFinder: a workflow for the identification of human papillomaviruses from high-throughput amplicon sequencing
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Robitaille, Alexis, Brancaccio, Rosario N., Dutta, Sankhadeep, Rollison, Dana E., Leja, Marcis, Fischer, Nicole, Grundhoff, Adam, Gheit, Tarik, Tommasino, Massimo, and Olivier, Magali
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- 2020
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231. Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial
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Bégin, Philippe, Callum, Jeannie, Jamula, Erin, Cook, Richard, Heddle, Nancy M., Tinmouth, Alan, Zeller, Michelle P., Beaudoin-Bussières, Guillaume, Amorim, Luiz, Bazin, Renée, Loftsgard, Kent Cadogan, Carl, Richard, Chassé, Michaël, Cushing, Melissa M., Daneman, Nick, Devine, Dana V., Dumaresq, Jeannot, Fergusson, Dean A., Gabe, Caroline, Glesby, Marshall J., Li, Na, Liu, Yang, McGeer, Allison, Robitaille, Nancy, Sachais, Bruce S., Scales, Damon C., Schwartz, Lisa, Shehata, Nadine, Turgeon, Alexis F., Wood, Heidi, Zarychanski, Ryan, Finzi, Andrés, and Arnold, Donald M.
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- 2022
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232. Socioeconomic Factors Influence Physical Activity and Sport in Quebec Schools
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Morin, Pascale, Lebel, Alexandre, Robitaille, Éric, and Bisset, Sherri
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Background: School environments providing a wide selection of physical activities and sufficient facilities are both essential and formative to ensure young people adopt active lifestyles. We describe the association between school opportunities for physical activity and socioeconomic factors measured by low-income cutoff index, school size (number of students), and neighborhood population density. Methods: A cross-sectional survey using a 2-stage stratified sampling method built a representative sample of 143 French-speaking public schools in Quebec, Canada. Self-administered questionnaires collected data describing the physical activities offered and schools' sports facilities. Descriptive and bivariate analyses were performed separately for primary and secondary schools. Results: In primary schools, school size was positively associated with more intramural and extracurricular activities, more diverse interior facilities, and activities promoting active transportation. Low-income primary schools were more likely to offer a single gym. Low-income secondary schools offered lower diversity of intramural activities and fewer exterior sporting facilities. High-income secondary schools with a large school size provided a greater number of opportunities, larger infrastructures, and a wider selection of physical activities than smaller low-income schools. Conclusions: Results reveal an overall positive association between school availability of physical and sport activity and socioeconomic factors.
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- 2016
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233. “This drug turned me into a robot”: an actor–network analysis of a web-based ethnographic study of psychostimulant use
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Robitaille, Caroline
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- 2018
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234. Nanostructured substrates for multi-cue investigations of single cells
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Christodoulides, Joseph A., Christophersen, Marc, Liu, Jinny L., Delehanty, James B., Raghu, Deepa, Robitaille, Michael, Byers, Jeff M., and Raphael, Marc P.
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- 2018
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235. Predictive Factors for Successful Same-Day Discharge After Minimally Invasive Colectomy and Stoma Reversal
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Paradis, Tiffany, Robitaille, Stephan, Wang, Anna, Gervais, Camille, Liberman, A. Sender, Charlebois, Patrick, Stein, Barry L., Fiore, Julio F., Feldman, Liane S., and Lee, Lawrence
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Video Abstract1_j8zdcurtKaltura
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- 2024
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236. Consumption of low nutritive value foods and cardiometabolic risk factors among French-speaking adults from Quebec, Canada: the PREDISE study
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Brassard, Didier, Laramée, Catherine, Provencher, Véronique, Vohl, Marie-Claude, Robitaille, Julie, Lemieux, Simone, and Lamarche, Benoît
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- 2019
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237. Accounting for spatial autocorrelation improves the estimation of climate, physical environment and vegetation’s effects on boreal forest’s burn rates
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Portier, Jeanne, Gauthier, Sylvie, Robitaille, André, and Bergeron, Yves
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- 2017
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238. WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner
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Brown, K, Yang, P, Salvador, D, Kulikauskas, R, Ruohola-Baker, H, Robitaille, A M, Chien, A J, Moon, R T, and Sherwood, V
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- 2017
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239. Current knowledge and interest of French Canadians regarding nutrigenetics
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Vallée Marcotte, Bastien, Cormier, Hubert, Garneau, Véronique, Robitaille, Julie, Desroches, Sophie, and Vohl, Marie-Claude
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- 2019
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240. Metabolism as an early predictor of DPSCs aging
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Macrin, Dannie, Alghadeer, Ammar, Zhao, Yan Ting, Miklas, Jason W., Hussein, Abdiasis M., Detraux, Damien, Robitaille, Aaron M., Madan, Anup, Moon, Randall T., Wang, Yuliang, Devi, Arikketh, Mathieu, Julie, and Ruohola-Baker, Hannele
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- 2019
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241. Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency
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Mathieu, J., Detraux, D., Kuppers, D., Wang, Y., Cavanaugh, C., Sidhu, S., Levy, S., Robitaille, A. M., Ferreccio, A., Bottorff, T., McAlister, A., Somasundaram, L., Artoni, F., Battle, S., Hawkins, R. D., Moon, R. T., Ware, C. B., Paddison, P. J., and Ruohola-Baker, H.
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- 2019
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242. The impact of restorative proctectomy versus permanent colostomy on health-related quality of life after rectal cancer surgery using the patient-generated index.
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Robitaille, Stephan, Maalouf, Michael F., Penta, Ruxandra, Joshua, Temitope Grace, Liberman, A. Sender, Fiore, Julio F., Feldman, Liane S., and Lee, Lawrence
- Abstract
The impact of bowel dysfunction versus colostomy on quality of life after rectal cancer surgery is poorly understood. To evaluate the quality of life after rectal cancer surgery in patients with colostomy versus restorative proctectomy. A mixed-methods study measuring quality of life using the Patient-Generated Index, patients were asked to list up to 5 areas of their life affected by their surgery. Areas were then weighted according to patients' preferences for improvement to generate a score from 0-100. The areas reported by patients were linked to the International Classification of Functioning for content analysis. Bowel dysfunction was measured using the low anterior resection syndrome score, and patients were then grouped according to (1) colostomy, (2) no/minor, or (3) major low anterior resection syndrome. Quality of life was compared between groups. Overall, 121 patients were included (colostomy n = 39, restorative proctectomy n = 82). There were no differences in demographics, neoadjuvant radiotherapy, or time to follow-up between groups. In the restorative proctectomy group, 53% had no/minor, and 47% had major low anterior resection syndrome. Overall, patients with colostomy had significantly lower quality-of-life scores than those with restorative proctectomy. However, patients with major low anterior resection syndrome scored similarly to those with colostomy. On content analysis, patients with colostomies reported more problems with sexual function, body image, and sports. Patients with restorative proctectomy reported more problems with sleep, using transportation, and taking care of themselves. Colostomy has a more detrimental impact on quality of life than restorative proctectomy. However, bowel dysfunction severity is important to consider. The patient experience between treatments differs. [ABSTRACT FROM AUTHOR]
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- 2023
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243. Speeding up for a son in Turkey.
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Robitaille, Marie-Claire and Aydede, Yigit
- Abstract
Copyright of Canadian Journal of Development Studies is the property of Routledge and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2023
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244. Perceptions of Teaching Practices Regarding Questioning and Discussion Techniques
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Robitaille, Yvette Jeannine Powell
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Questioning and discussion techniques are effective instructional methods that develop critical thinking and problem solving skills. Despite these positive associations, there is inconsistent implementation of these techniques across disciplines and grade levels, often resulting in a negative effect on student achievement. This collective case study explored elementary, middle, and high school teachers and evaluators' perceptions of teaching practices regarding exemplary questioning and discussion techniques. The theoretical framework that guided this study was social constructivism, which postulates that individuals construct their knowledge in social settings as they grapple with dilemmas that are within an approximate range of their academic levels. Participants included 9 teachers who earned exemplary marks on their evaluations for questioning and discussion techniques and 3 evaluators who awarded teachers exemplary marks. Data gathering included semistructured interviews of teachers and evaluators, evaluation summaries, and lesson plans. Analysis was inductive using constant comparison to identify themes. Findings indicated these exemplary teachers created an environment of respect, established a culture for learning, completed courses of study, and engaged in collegial interactions with peers. Recommendations include designing professional development opportunities for teachers to improve questioning and discussion techniques. These findings guided the development of an interactive, ongoing teacher training program designed to guide teachers through a systematic, reflective process using self-analysis of teaching practices. Improvement in teaching practices, which may improve student achievement, is a positive social change that could result from this project study. [The dissertation citations contained here are published with the permission of ProQuest LLC. Further reproduction is prohibited without permission. Copies of dissertations may be obtained by Telephone (800) 1-800-521-0600. Web page: http://www.proquest.com/en-US/products/dissertations/individuals.shtml.]
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- 2013
245. A machine learning approach for online automated optimization of super-resolution optical microscopy
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Durand, Audrey, Wiesner, Theresa, Gardner, Marc-André, Robitaille, Louis-Émile, Bilodeau, Anthony, Gagné, Christian, De Koninck, Paul, and Lavoie-Cardinal, Flavie
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- 2018
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246. Transcutaneous cardiac pacing competency among junior residents undergoing an ACLS course: impact of a modified high fidelity manikin
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Ranger, Caroline, Paradis, Marie-Rose, Morris, Judy, Perron, Roger, Drolet, Pierre, Cournoyer, Alexis, Paquet, Jean, and Robitaille, Arnaud
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- 2018
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247. Astrocytes detect and upregulate transmission at inhibitory synapses of somatostatin interneurons onto pyramidal cells
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Matos, Marco, Bosson, Anthony, Riebe, Ilse, Reynell, Clare, Vallée, Joanne, Laplante, Isabel, Panatier, Aude, Robitaille, Richard, and Lacaille, Jean-Claude
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- 2018
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248. Pregnant women’s views on how to promote the use of a decision aid for Down syndrome prenatal screening: a theory-informed qualitative study
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Agbadjé, Titilayo Tatiana, Menear, Matthew, Dugas, Michèle, Gagnon, Marie-Pierre, Rahimi, Samira Abbasgholizadeh, Robitaille, Hubert, Giguère, Anik M. C., Rousseau, François, Wilson, Brenda J., and Légaré, France
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- 2018
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249. Validation of a self-administered web-based 24-hour dietary recall among pregnant women
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Savard, Claudia, Lemieux, Simone, Lafrenière, Jacynthe, Laramée, Catherine, Robitaille, Julie, and Morisset, Anne-Sophie
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- 2018
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250. Méthodes peropératoires pour améliorer l’estimation des pertes sanguines chirurgicales et par voie vaginale en cours de césarienne
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Ducloy-Bouthors, A.-S., Cordier, D., Ancelet, F., Robitaille, S., Hernout, M.-F., Lemeur, C., Depret-Mosser, S., Richart, P., and Barre-Drouard, C.
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- 2017
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