423 results on '"P. Nigri"'
Search Results
202. Surgical Resection Is Necessary To Maximize Tumor Control in Function-Preserving, Aggressive Chemoradiation Protocols for Advanced Squamous Cancer of the Head and Neck (Stage III and IV)
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Wanebo, H., Chougule, P., Ready, N., Safran, H., Ackerley, W., Koness, R. J., McRae, R., Nigri, P., Leone, L., Radie-Keane, K., Reiss, P., and Kennedy, T.
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- 2001
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203. Papillary muscles and tendinous cords of the right ventricle of the human heart morphological characteristics
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Nigri, G. R., Di Dio, L. J. A., and Baptista, C. A. C.
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- 2001
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204. Ressonância magnética é útil em valvopatia Magnetic resonance is useful in heart valvular disease
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Marcelo Nigri, Carlos Eduardo Rochitte, and Max Grinberg
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Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Published
- 2006
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205. Enquadramentos, cenas dissensuais e o aparecer antierárquico: ação política e resistência em Judith Butler e Jacques Rancière.
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Salgueiro Marques, Ângela Cristina, Nigri Veloso, Lucas Henrique, and Máximo Prado, Marco Aurélio
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FABLES ,RECOGNITION (Philosophy) ,STRUGGLE - Abstract
Copyright of Comunicação, Mídia e Consumo is the property of Escola Superior de Propaganda e Marketing and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2021
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206. Letter to the Editor of Annals of Surgical Oncology Concerning “Robotic versus Open Pancreatectomy: A Systematic Review and Meta-analysis”
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Petrucciani, Niccolò, Nigri, Giuseppe R., and Ramacciato, Giovanni
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- 2014
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207. Fourier transform infrared and fluorescence spectroscopy for analysis of vegetable oils
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Nigri S. and Oumeddour R.
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Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Fourier transform infrared (FTIR) and fluorescence spectroscopy, combined with chemometric approaches have been developed to analysis of extra virgin olive oil adulterated with pomace olive oil. The measurements were made on pure vegetable oils: extra virgin oil, pomace olive oil and that adulterated with varying concentration of pomace olive oil. Today, the application of FTIR spectroscopy has increased in food studied, and particularly has become a powerful analytical tool in the study of edible oils and fats. The spectral regions where the variations were observed chosen for developing models and cross validation was used. The synchronous fluorescence spectrometry takes advantage of the hardware capability to vary both the excitation and emission wavelengths during the analysis with constant wavelength difference is maintained between the two. The region between 300 and 400 nm is attributed to the tocopherols and phenols, the derivatives of vitamin E are associated with the region 400–600 nm and the bands in the region of 600–700 nm are attributed to the chlorophyll and peophytin pigments. The results presented in this study suggest that FTIR and fluorescence may be a useful tool for analysis and detecting adulteration of extra virgin olive oil with pomace oil.
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- 2013
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208. The 5th anniversary of 'Patient Safety in Surgery' – from the Journal’s origin to its future vision
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Stahel Philip F, Smith Wade R, Hahnloser Dieter, Nigri Giuseppe, Mauffrey Cyril, and Clavien Pierre-Alain
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Surgery ,RD1-811 - Published
- 2012
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209. Physical Characterization and Durability of Blended Cements Based on Brick Powder
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Nigri, Ghania, Cherait, Yacine, and Nigri, Soraya
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This research work discusses both the physical and durability characteristics of newly blended cement containing waste crushed brick. This waste is used as a partial substitution for clinker in cement. Thus, blended cements are obtained by grinding and homogenizing clinker, waste brick, and gypsum. Four compositions containing 0%, 10%, 20%, and 30% of waste materials were prepared and submitted to various characterization tests.
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- 2020
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210. Histomorphological and inflammatory changes of white adipose tissue in gastrointestinal cancer patients with and without cachexia
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Molfino, Alessio, Carletti, Raffaella, Imbimbo, Giovanni, Amabile, Maria Ida, Belli, Roberta, Gioia, Cira R.T., Belloni, Elena, Spinelli, Francesco, Rizzo, Veronica, Catalano, Carlo, Nigri, Giuseppe, and Muscaritoli, Maurizio
- Abstract
During cancer cachexia, several alterations occur in peripheral tissues, and the adipose tissue may be involved during the catabolic state. We aimed at investigating histological rearrangement and infiltration of inflammatory cells in subcutaneous adipose tissue (SAT) of patients with cancer undergoing surgery, according to the presence/absence of cachexia. We considered gastrointestinal cancer patients and controls with non‐malignant diseases undergoing surgery. We collected SAT samples and performed histomorphological analyses [cross‐sectional area (CSA) and per cent of fibrosis] and immunohistochemistry to characterize the inflammatory cells. By computed tomography (CT) scan, we calculated SAT and visceral adipose tissue (VAT). We enrolled 51 participants (31 gastrointestinal cancer patients and 20 controls). In cancer patients, cachexia was present in 13/31 (42%). The CSA (μm2) of the adipocytes from SAT was reduced in cancer patients vs. controls (3148, inter‐quartile range 2574–3755 vs. 4474, inter‐quartile range 3654–5183) (P< 0.001), in particular in cachectic patients vs. non‐cachectic (median 2518 vs. median 3470) (P= 0.03) and in cachectic vs. controls (P< 0.001), as well as in non‐cachectic vs. controls (P= 0.04). The median per cent of fibrosis was higher in cancer patients vs. controls (9 vs. 3) (P= 0.0001), in particular in cachectic vs. non‐cachectic (13.35 vs. 7.13) (P= 0.03). We observed a higher number of macrophages (CD68) (P= 0.0001) and T lymphocytes (CD3) (P= 0.002) in SAT of cancer patients vs. controls, and the number of T lymphocytes was higher in cachectic vs. non‐cachectic patients (P= 0.025). Anorexic cancer patients showed in SAT a higher number of macrophages and T lymphocytes with respect to controls (P< 0.0001), whereas no difference was present between anorexic and non‐anorexic patients. At CT scan, cachectic patients showed lower VAT and SAT vs. non‐cachectic (VAT: 97.64 ± 40.79 vs. 212.53 ± 79.24, P= 0.0002; SAT: 126.27 ± 87.92 vs. 206.27 ± 61.93, P= 0.01, respectively). Cancer patients with low CSA, high degree of fibrosis, and high number of T lymphocytes presented with lower body mass index and lower SAT and VAT at CT scan (P≤ 0.01). We found histological alterations of SAT among gastrointestinal cancer patients and in particular significant changes in CSA, fibrosis, and inflammation when cachexia was present; the changes in histomorphological parameters of the adipocytes reflected alterations in adiposity at body composition analysis.
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- 2022
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211. Case Report: Incidental Finding of COVID-19 Infection after Positron Emission Tomography/CT Imaging in a Patient with a Diagnosis of Histoplasmosis and Recurring Fever.
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Stachera Stasiak, Camila Edith, Nigri, David Henrique, Cardoso, Fabrícius Rocha, de Almeida Rezende de Mattos, Raphael Santos, Gonçalves Martins, Philippe Alcântara, Silva Carvalho, Alysson Roncally, de Almeida, Sérgio Altino, Rodrigues, Rosana Souza, and Rosado-de-Castro, Paulo Henrique
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- 2021
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212. Tratamento interceptativo de má oclusão de Classe II severa com aparelho extrabucal de Thurow.
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Duarte CALDAS, Luciana, Paula NIGRI, Anna, Martins de ARAÚJO, Telma, and de Oliveira RUELLAS, Antônio Carlos
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Copyright of Clinical Orthodontics is the property of Dental Press International and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2021
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213. Giant inframuscular lipoma disclosed 14 years after a blunt trauma: A case report
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Nigri Giuseppe, Dente Mario, Valabrega Stefano, Beccaria Giacomo, Aurello Paolo, D'Angelo Francesco, Di Marzo Francesco, and Ramacciato Giovanni
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Medicine - Abstract
Abstract Introduction Lipoma is the most frequent benign tumor of the soft tissue. This lesion is often asymptomatic except in cases of enormous masses compressing nervous-vascular structures. Although the diagnosis is mostly clinical, imaging tools are useful to confirm the adipose nature of the lesion and to define its anatomic border. Sometimes, lipomas may be the result of a previous trauma, such as in this patient. Case presentation A 45-year-old man presented at our institution with a giant hard firm mass in the upper external quadrant of the right buttock disclosed after a weight loss diet. Subsequent magnetic resonance imaging showed a giant adipose mass developed beneath the large gluteal muscle and among the fibers of the medium and small gluteal muscles. When questioned on his medical history, the patient reported a blunt trauma of the lower back 14 years earlier. He underwent surgery and histological examination confirmed a giant lipoma. Conclusion Lipomas might result from a previous trauma. It is hypothesized that the trigger mechanism is activated by cytokine and growth factors released after the trauma. We herein present an exceptional case of a giant post-traumatic lipoma which caused a painful compression on the right sciatic nerve.
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- 2008
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214. Gastrointestinal stromal tumor of the anal canal: an unusual presentation
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Montrone Giuseppe, D'Angelo Francesco, Aurello Paolo, Valabrega Stefano, Dente Mario, Nigri Giuseppe R, Ercolani Giorgio, and Ramacciato Giovanni
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Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Gastrointestinal stromal tumors (GIST) of the stomach are the most frequent followed by those of the intestinal tract, while colon and rectum represent rare sites. GIST of the anal canal are extremely rare. They have been studied along with GIST of the rectum, as a single entity, and along with them they represent 5% of GIST. GIST arising from the anal canal account for only 2%–8% of the anorectal GIST. Thus anal GIST must be considered an exceptional case. Case presentation A 78-year-old man was referred to our Institution for an anal mass, in absence of any symptom. The patient was treated by local excision. An histological diagnosis of a low grade GIST was made. No further treatment was necessary. No local recurrence of distant metastases were found at follow-up. Conclusion At the moment, only ten cases of c-kit positive anal GIST are reported in the literature. These few data are not sufficient to establish a widely accepted approach for this neoplasia. We recommend to perform an initial local excision, to define the risk of aggressive behavior and the resection margins and proceed to a more aggressive treatment, if the GIST belongs to high or very high risk group. The role of adjuvant therapy is still uncertain. Although inhibitors of tyrosine-kinase receptor needs further studies before their routine use, their role in case of distant or local recurrence has been accepted. Patients' close follow up is mandatory to disclose as soon as possible local recurrences or metastases.
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- 2007
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215. An Abdominal Mass
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Nigri, Giuseppe R., Aurello, Paolo, and Ramacciato, Giovanni
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- 2011
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216. Emergency laparotomy for misdiagnosed biliary cystadenoma originating from caudate lobe
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Colarossi Cristina, Bellagamba Riccardo, Aurello Paolo, D'Angelo Francesco, Nigri Giuseppe R, Ramacciato Giovanni, Pilozzi Emanuela, and Del Gaudio Massimo
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Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Biliary cystadenoma is a rare benign neoplasm, which is often misdiagnosed for a hepatic abscess or a hydatid cyst that tends to recur and is at risk for progression to malignant neoplasm. Case presentation This case describes a 30-year-old woman admitted to our institution in an emergency setting. The patient was originally misdiagnosed as affected by a hepatic hydatid cyst at another hospital, and then emergently treated at our Institution for severe abdominal pain. Histologic evaluation of the cyst showed that it was a biliary cystadenoma and, therefore, the patient underwent a hepatic resection in order to completely remove the lesion. Conclusion Complete excision of any suspicious hepatic cystic lesion remains the best method for diagnosis and treatment of cystadenoma. Incomplete excision of most biliary cystadenoma results in a higher rate of recurrence and the risk of malignant transformation. We report this case to elucidate the clinical presentation, preoperative evaluation, and surgical treatment of these rare lesions.
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- 2006
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217. Giant hepatic adenoma with bone marrow metaplasia not associated with oral contraceptive intake
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Pilozzi Emanuela, Rossi Simone, Pezzoli Francesca, D'Angelo Francesco, Aurello Paolo, Nigri Giuseppe R, Ramacciato Giovanni, Ercolani Giorgio, and Ravaioli Matteo
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Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Hepatocellular adenomas are the most common benign liver tumors. They are usually related to oral contraceptive intake. Case presentation This case describes a 58-year-old woman admitted to our institution for a hepatic mass incidentally discovered during a routine examination. The patient, who was never on oral contraceptives, was asymptomatic upon admission. She underwent a thorough diagnostic evaluation and then a hepatic right trisegmentectomy. The histologic evaluation of the mass showed that it was a hepatocellular adenoma with areas of bone marrow metaplasia. Conclusion Bone marrow metaplasia has rarely been found associated to liver tumors. The presence of marrow-derived hepatic progenitor cells might be the source of both adenoma hepatocytes and bone marrow differentiated cells. To our knowledge, this is only the second case in the English literature in which areas of bone marrow metaplasia were found in a hepatocellular adenoma.
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- 2006
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218. Transtornos alimentares e obesidade, 2ª edição
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Michelle Nigri Levitan and Antonio Egidio Nardi
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Psychiatry ,RC435-571 - Published
- 2006
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219. Left-sided portal hypertension after pancreatoduodenectomy with resection of the portal/superior mesenteric vein confluence. Results of a systematic review.
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Petrucciani, Niccolo, Debs, Tarek, Rosso, Edoardo, Addeo, Pietro, Antolino, Laura, Magistri, Paolo, Gugenheim, Jean, Ben Amor, Imed, Aurello, Paolo, D'Angelo, Francesco, Nigri, Giuseppe, Di Benedetto, Fabrizio, Iannelli, Antonio, and Ramacciato, Giovanni
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Pancreatoduodenectomy with synchronous resection of the portal vein/superior mesenteric vein confluence may result in the development of left-sided portal hypertension. Left-sided portal hypertension presents with splenomegaly and varices and may cause severe gastrointestinal bleeding. The aim of the study is to review the incidence, treatment, and preventive strategies of left-sided portal hypertension. A systematic literature search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement to identify all studies published up to September 30, 2019 reporting data on patients with left-sided portal hypertension after pancreatoduodenectomy with venous resection. Eight articles including 829 patients were retrieved. Left-sided portal hypertension occurred in 7.7% of patients who had splenic vein preservation and 29.4% of those having splenic vein ligation. Fourteen cases of gastrointestinal bleeding owing to left-sided portal hypertension were reported at a mean interval of 28 months from pancreatoduodenectomy. Related mortality at 1 month was 7.1%. Treatment of left-sided portal hypertension consisted of splenectomy in 3 cases (21%) and colectomy in 1 (7%) case, whereas radiologic, endoscopic procedures or conservative treatments were effective in the other cases (71%). Left-sided portal hypertension represents a potentially severe complication of pancreatoduodenectomy with venous resection occurring at greater incidence when the splenic vein is ligated and not reimplanted. Left-sided portal hypertension-related gastrointestinal bleeding although rare can be managed depending on the situation by endoscopic, radiologic procedures or operative intervention with low related mortality. [ABSTRACT FROM AUTHOR]
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- 2020
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220. Covid-19 in the State of Ceará: behaviors and beliefs in the arrival of the pandemic.
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Ferreira Lima, Danilo Lopes, Angelim Dias, Aldo, Sabóia Rabelo, Renata, Demes da Cruz, Igor, Carvalho Costa, Samuel, Noronha Nigri, Flávia Maria, and Rabelo Neri, Jiovanne
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COVID-19 pandemic ,COVID-19 ,PANDEMICS ,ELEMENTARY education ,BELIEF & doubt ,ELEMENTARY schools - Abstract
This study aimed to evaluate the behavioral aspects and beliefs of the population of Ceará in the face of the COVID-19 pandemic. An online questionnaire was conducted on sociodemographic aspects and opinions related to the pandemic. Absolute and relative frequencies were calculated, the association between variables was performed with Chi-square, and the level of significance was 5%. The final sample had 2,259 participants, and an association was observed between females and perceiving themselves with a high risk of infection (p = 0.044) and males with non-performance of voluntary quarantine (p < 0.001). People aged 80 years and over were partially quarantined due to the flow of people at home (p < 0.001). Participants with elementary school education had a lower risk of infection than participants with a higher level of education (p < 0.001). This group includes people who did voluntary quarantine the least (p < 0.001). Participants living in the inland region of the state had less direct contact with someone tested positive for the Coronavirus (p = 0.031) and are less reclusive (p < 0.001). We can conclude that the approach to the COVID-19 pandemic varies by social aspects, such as gender, age, education, and place of residence, as well as the belief system of the population of the State of Ceará. [ABSTRACT FROM AUTHOR]
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- 2020
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221. Como confeccionar batente de desoclusão anterior sem bandas ortodônticas.
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CALDAS, Luciana Duarte, NIGRI, Anna Paula, and SANT'ANNA, Eduardo Franzotti
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Copyright of Revista Clínica de Ortodontia Dental Press is the property of Dental Press International and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
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222. Diagnostic delay does not influence survival of pancreatic cancer patients
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Stornello, Caterina, Archibugi, Livia, Stigliano, Serena, Vanella, Giuseppe, Graglia, Benedetta, Capalbo, Carlo, Nigri, Giuseppe, and Capurso, Gabriele
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Background Most pancreatic ductal adenocarcinoma patients present with advanced disease. Whether it is possible to increase survival by earlier diagnosis is unclear.Objective The purpose of this study was to investigate the association between presenting complaints and risk factors for pancreatic cancer with diagnostic delay, stage and survival.Methods This was a single-centre retrospective cohort study. Consecutive patients were interviewed and data on demographics, medical history, risk factors and complaints leading to pancreatic ductal adenocarcinoma diagnosis and disease stage were recorded. Diagnostic delay was considered as time between first complaint and diagnosis. Patients received appropriate treatments and their outcome was recorded in a dedicated database. The Chi-square test for comparison of categorical variables and the Mann–Whitney test for continuous variables were employed with Bonferroni corrections. Correlation between continuous variables was evaluated by means of the Spearman correlation coefficient. Survival analysis was performed with the Kaplan–Meier method and a log-rank test.Results The median diagnostic delay for 477 pancreatic ductal adenocarcinoma patients was two months (interquartile range 1–5), being significantly shorter for patients presenting with jaundice compared with those with pain, weight loss, diabetes (p< 0.001). The global rate of metastatic disease at diagnosis was 40%, being only 22% in those presenting with jaundice. The median diagnostic delay, however, was not significantly different among disease stages but was significantly longer in patients with a body mass index>25 kg/m2. The median survival time was seven months. Factors associated with worse survival at the multivariable analysis were older age (hazard ratio 1.02 per year), metastatic disease (hazard ratio 2.12) and pain as presenting complaint (hazard ratio 1.32), while diagnostic delay was not.Conclusion While some complaints are associated with a shorter diagnostic delay and less advanced disease stage, we could not demonstrate that delay is associated with survival, possibly suggesting that prevention rather than early recognition is important to tackle pancreatic cancer lethality.
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- 2020
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223. Concurrent chemoradiotherapy with weekly paclitaxel and carboplatin for locally advanced head and neck cancer: Long-term follow-up of a Brown University Oncology Group Phase II Study (HN-53)
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Ritesh Rathore, Kathie Radie-Keane, Harold J. Wanebo, P. Nigri, Prakash Chougule, Teresa Kennedy, Muhammad S. Akhtar, Neal Ready, Robert G. McRae, and James Koness
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Adult ,Male ,Mucositis ,medicine.medical_specialty ,Paclitaxel ,medicine.medical_treatment ,Urology ,Phases of clinical research ,Carboplatin ,chemistry.chemical_compound ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Humans ,External beam radiotherapy ,Survival rate ,Aged ,business.industry ,Head and neck cancer ,Radiotherapy Dosage ,Neck dissection ,Middle Aged ,medicine.disease ,Combined Modality Therapy ,Survival Rate ,Otorhinolaryngology ,chemistry ,Head and Neck Neoplasms ,Neck Dissection ,Female ,Neoplasm Recurrence, Local ,Nuclear medicine ,business ,Chemoradiotherapy ,Follow-Up Studies - Abstract
Background. A phase II study was conducted using concurrent paclitaxel, carboplatin, and external beam radiotherapy (RT) in patients with advanced head and neck cancer. Methods. Forty-three patients (stage III, n = 12; stage IV, n = 31) were treated with 8 cycles of weekly paclitaxel (60 mg/m2), carboplatin (area under the curve [AUC] = 1), and RT (1.8 Gy daily; total dose, 66–72 Gy). Patients with initially palpable lymph nodes underwent neck dissection. Results. The overall clinical response rate was 91% (65% complete, 26% partial). Severe mucositis occurred in 37 (90%) patients, necessitating hospitalization in 13 (31%) patients. With a median follow-up of 49 months, the locoregional and distant failure rates were 26% and 21%, respectively. Conclusions. Concurrent paclitaxel, carboplatin, and RT for advanced head and neck cancer results in high complete response rates. Long-term follow-up has revealed the curative potential of this regimen, though the doses used resulted in unacceptable toxicity. © 2007 Wiley Periodicals, Inc. Head Neck 2008
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- 2008
224. Stereotactic electroencephalography in humans reveals multisensory signal in early visual and auditory cortices
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Ferraro, Stefania, Van Ackeren, Markus J., Mai, Roberto, Tassi, Laura, Cardinale, Francesco, Nigri, Anna, Bruzzone, Maria Grazia, D'Incerti, Ludovico, Hartmann, Thomas, Weisz, Nathan, and Collignon, Olivier
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Unequivocally demonstrating the presence of multisensory signals at the earliest stages of cortical processing remains challenging in humans. In our study, we relied on the unique spatio-temporal resolution provided by intracranial stereotactic electroencephalographic (SEEG) recordings in patients with drug-resistant epilepsy to characterize the signal extracted from early visual (calcarine and pericalcarine) and auditory (Heschl's gyrus and planum temporale) regions during a simple audio-visual oddball task. We provide evidences that both cross-modal responses (visual responses in auditory cortex or the reverse) and multisensory processing (alteration of the unimodal responses during bimodal stimulation) can be observed in intracranial event-related potentials (iERPs) and in power modulations of oscillatory activity at different temporal scales within the first 150 msec after stimulus onset. The temporal profiles of the iERPs are compatible with the hypothesis that MSI occurs by means of direct pathways linking early visual and auditory regions. Our data indicate, moreover, that MSI mainly relies on modulations of the low-frequency bands (foremost the theta band in the auditory cortex and the alpha band in the visual cortex), suggesting the involvement of feedback pathways between the two sensory regions. Remarkably, we also observed high-gamma power modulations by sounds in the early visual cortex, thus suggesting the presence of neuronal populations involved in auditory processing in the calcarine and pericalcarine region in humans.
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- 2020
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225. Total Pancreatectomy for Pancreatic Carcinoma
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Petrucciani, Niccolo, Nigri, Giuseppe, Giannini, Giulia, Sborlini, Elena, Antolino, Laura, de'Angelis, Nicola, Gavriilidis, Paschalis, Valente, Roberto, Lainas, Panagiotis, Dagher, Ibrahim, Debs, Tarek, and Ramacciato, Giovanni
- Abstract
The role of total pancreatectomy (TP) to treat pancreatic carcinoma is still debated. The aims of this study were to systematically review the previous literature and to summarize the indications and results of TP for pancreatic carcinoma. A systematic search was performed to identify all studies published up to November 2018 analyzing the survival of patients undergoing TP for pancreatic carcinoma. Clinical effectiveness was synthetized through a narrative review with full tabulation of results. Six studies published between 2009 and 2016 were retrieved, including 316 patients. The major indication was positive pancreatic margin at frozen section during partial pancreatectomy. The overall morbidity ranged from 36% to 69%, and mortality from 0% to 27%. Overall survival ranged from 52.7% to 67% at 1 year, from 20% to 42% at 3 years of follow-up, whereas the 5-year estimated overall survival ranged from 4.5% to 21.9%. Total pancreatectomy has an important role in the armamentarium of pancreatic surgeons. Postoperative morbidity and mortality are not negligible, but a trend for better postoperative outcomes in recent years is noticed. Mortality related to difficult glycemic control is rare. Long-term survival is comparable with survival after partial pancreatectomy for carcinoma.
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- 2020
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226. AVALIAÇÃO DE TAMANHO DE BOLHAS EM COLUNA DE FLOTAÇÃO POR ANÁLISE DE IMAGEM USANDO OS SOFTWARES IMAGEJ E APBS.
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de Almeida, Renata Nigri, da Cruz Barreto, Estevão Gomes, and Bianquini Couto, Hudson Jean
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IMAGE processing ,BUBBLES ,FLOTATION ,PLATINUM ,DIGITAL image processing - Abstract
Copyright of Tecnologia em Metalurgia, Materiais e Mineração is the property of Associacao Brasileira de Metalurgia e Materiais and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
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227. Uma forma simples e eficiente para evitar irritações na pele durante a utilização de máscaras faciais.
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CALDAS, Luciana Duarte, NIGRI, Anna Paula, de SOUZA, Margareth Maria Gomes, and BOLOGNESE, Ana Maria
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- 2019
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228. Customized Cap to Keep a Facemask Properly Positioned During Sleep.
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DUARTE CALDAS, LUCIANA, NIGRI, ANNA PAULA, and FRANZOTTI SANT'ANNA, EDUARDO
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SLEEP positions ,EAR canal ,TEXTILE arts - Published
- 2021
229. WITHDRAWN: In vivobioluminescence-based monitoring of liver metastases from colorectal cancer: An experimental model
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Magistri, Paolo, Battistelli, Cecilia, Toietta, Gabriele, Strippoli, Raffaele, Sagnotta, Andrea, Forgione, Antonello, Di Benedetto, Fabrizio, Uccini, Stefania, Vittorioso, Paola, D’Angelo, Francesco, Aurello, Paolo, Ramacciato, Giovanni, and Nigri, Giuseppe
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The journal transferred to Wolters Kluwer effective 1 January 2018 and all Articles in Press will be published by the new publisher as a result. This Article in Press has therefore been withdrawn from this platform. Should you have any queries please contact the Editor-in-Chief, Prof. Abdulmonem Al-Hayani at hayani30@hotmail.com. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/our-business/policies/article-withdrawal.
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- 2024
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230. Italian immunization calendar implementation: Time to optimize number of vaccination appointments?
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Poscia, Andrea, Lo Giudice, Milena, Nigri, Luigi, Perone, Vanessa, Russo, Rocco, Bresesti, Ilia, and Agosti, Massimo
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ABSTRACTIn the Italian vaccination schedule, at least six vaccination appointments are scheduled in the first year of life. This implies more discomfort for both the patient and the parents. This was particularly evident during the COVID-19 pandemic, during which several appointments were missed. A UK experience with three injectable vaccines and an oral one co-administered at the same appointment (4-in-1) at 2 and 4 months of age showed interesting results. The vaccination coverage was high, consistent with previous practice, and no relevant increase in adverse events was reported. Translating the UK experience into the Italian context would not be immediate, due to several organizational and social issues. Nevertheless, this option warrants some further considerations, which are discussed in this manuscript.
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- 2023
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231. CO-13.1.5 - T1-WEIGHTED BRAIN MRI: QUALITY ASSESSMENT, VARIABILITY AND REPRODUCIBILITY OF ANATOMICAL MEASUREMENTS IN THE RIN–NEUROIMAGING NETWORK.
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Bosco, P., Lancione, M., Retico, A., Nigri, A., Aquino, D., Baglio, F., Carne, I., Ferraro, S., Giulietti, G., Napolitano, A., Palesi, F., Pavone, L., Savini, G., Tagliavini, F., Bruzzone, M.G., Wheeler-Kingshott, C.A.M. Gandini, Tosetti, M., and Biagi, L.
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- 2023
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232. Burnout in Primary Care Pediatrics and the Additional Burden from the COVID-19 Pandemic.
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Nigri, Luigi, Carrasco-Sanz, Angel, Pop, Tudor Lucian, Giardino, Ida, Vural, Mehmet, Ferrara, Pietro, Indrio, Flavia, and Pettoello-Mantovani, Massimo
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- 2023
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233. A fobia e o pânico em suas relações com a angústia
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Vera Lopes Besset, Kátia Kac Nigri, and Leonardo Pinto de Almeida
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phobia ,panic ,anguish ,psychoanalytical clinic. ,Psychology ,BF1-990 - Abstract
Nesse texto, objetivou-se indicar as relações da angústia com as manifestações patológicas da fobia e do pânico, demonstrando a adequação da proposta de intervenção terapêutica, dentro de uma perspectiva psicanalítica. Esse trabalho se refere a resultados parciais de pesquisa teórica sobre a angústia, onde o método utilizado é o de análise crítica dos conceitos. Neste, buscamos investigar a coerência entre as formulações teóricas de S. Freud e J. Lacan, já clássicas, com o que se observa na clínica hoje. Para tanto, valemo-nos da referência a dados da experiência clínica. A investigação aponta para a adequação da concepção psicanalítica da fobia e do pânico, pois confirma o caráter de substituto que tem o objeto temido. É esta mesma natureza que o torna permeável à ação da fala, no dispositivo de linguagem que é o da clínica psicanalítica.
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234. Efeito do plasma de oxigênio na dentina previamente exposta ao NaOCl
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Maíra do PRADO, Rafael Nigri ROIZENBLIT, Laura Villela PACHECO, Carlos Augusto de Melo BARBOSA, and Renata Antoun SIMÃO
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Plasma gases ,sodium hypochlorite ,topography ,surface properties ,wettability ,Medicine ,Dentistry ,RK1-715 - Abstract
Resumo Introdução O tratamento de plasma é uma tecnologia eficaz que pode manter as propriedades internas dos materiais inalteradas após o tratamento, modificando apenas a superfície. Objetivo Avaliar o efeito do plasma de oxigênio na dentina previamente exposta ao NaOCl 6%. Material e método Foram utilizados 60 incisivos bovinos. A coroa foi removida, a raiz foi dividida e as faces planificadas, totalizando 120 segmentos referentes ao terço cervical. As amostras foram divididas em dois grupos: controle (imersa em NaOCl 6%, lavada com água destilada, seca, imersa em EDTA 17%, lavada e seca) e plasma de oxigênio (após tratamento descrito no grupo controle, plasma de oxigênio foi aplicado por 30 s). As amostras foram avaliadas qualitativamente em relação à topografia por microscopia eletrônica de varredura, utilizando-se microfotografias com ampliação de 1.000×. O goniômetro Ramé-hart foi utilizado para a mensuração do ângulo de contato entre as superfícies e as seguintes soluções foram utilizadas: água, etilenoglicol e di-iodometano. Em seguida, a energia de superfície, representada pelas componentes polar e dispersiva, foi calculada. Avaliou-se também o escoamento dos cimentos Pulp Canal Sealer EWT (PCS) e Real Sal SE (RS) na superfície dentinária. Os dados foram analisados estatisticamente utilizando os testes Kruskal-Wallis e Mann-Whitney U (p
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235. População de protozoários ruminais em novilhos zebuínos alimentados com ou sem volumoso
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A.C.A. Nigri, I.C.O. Ribeiro, E.A. Vieira, M.L.F. Silva, G.F Virgínio-Júnior, F.O. Abrão, L.C. Geraseev, and E.R. Duarte
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ciliados ,microbiota ruminal ,pecuária de corte ,acidose ruminal ,terminação ,Animal culture ,SF1-1100 - Abstract
ABSTRACT This study aimed to quantify and identify the profile of the rumen protozoa population of beef steers fed with or without roughage. Nellore crossbred steers raised in extensive system on lignified tropical pastures with mineral supplementation and steers confined for 60 days only receiving pelletized concentrate and whole corn kernels were evaluated. After slaughter, rumen fluid was collected and one ml aliquots were diluted in nine ml formaldehyde solution at 10%. The counts of small, medium and large protozoa were held in Sedgewick Rafter chambers and identification of genus was possible after staining lugol and optical microscope with a 40X objective. The concentration of rumen protozoa positively correlated with pH ruminal. Cattle fed without roughage had significantly lower rumen protozoa population (P
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236. Preoperative chemoradiation coupled with aggressive resection as needed ensures near total control in advanced head and neck cancer
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Prakash Chougule, Bernard F. Cole, Neal Ready, P. Nigri, Howard Safran, Wallace Akerley, Robert G. McRae, R. James Koness, Louis A. Leone, Harold J. Wanebo, and Banice M. Webber
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Adult ,Male ,Radiation-Sensitizing Agents ,medicine.medical_specialty ,Paclitaxel ,medicine.medical_treatment ,Antineoplastic Agents ,Preoperative care ,Carboplatin ,chemistry.chemical_compound ,Preoperative Care ,medicine ,Humans ,Prospective Studies ,Survival rate ,Aged ,Chemotherapy ,business.industry ,Head and neck cancer ,Radiotherapy Dosage ,Neck dissection ,General Medicine ,Middle Aged ,medicine.disease ,Combined Modality Therapy ,Surgery ,Survival Rate ,Radiation therapy ,chemistry ,Epidermoid carcinoma ,Head and Neck Neoplasms ,Carcinoma, Squamous Cell ,Female ,business - Abstract
background Preoperative chemotherapy or chemoradiation protocols are generally associated with high clinical response rates, but limited pathologic responses for large primary tumors. We have initiated a prospective phase II study of weekly paclitaxel 60 mg/M2, and carboplatin (AUC of 1) plus concurrent fractionated external beam radiation (45 Gy) followed by organ-preserving (or function restorative) surgery when applicable to maximize local-regional tumor control. patients and methods Operable patients staged by triple endoscopy received a percutaneous endoscopic gastrostomy and vigorous dental and nutritional support during therapy. Weekly paclitaxel 60 mg/M2, carboplatin (AUC of 1), and radiation 45 Gy were given with rebiopsy of the primary site at 5 weeks. Patients with positive biopsy had definitive surgery in 4 to 5 weeks. Patients with negative biopsy-results received 3 additional weeks of radiation, to a total dose of 72 Gy plus carboplatin and paclitaxel. results The 35 patients were 29 men and 6 women, aged 40 to 71 years, with stage III (12) or stage IV (23) cancer. The site of the cancer was oral cavity, 10; base of tongue, 3; oropharynx, 3; hypopharynx, 4; larynx, 12 (glottic, 6; supraglottic, 6), unknown primary, 2; other, nasal cavity, 1. Of 34 evaluable patients, 16 (47%) had a complete clinical response (CR) and 18 (53%) had a partial response (PR); total clinical response rate was 100%. A pathologic CR at the primary site occurred in 23 of 34 patients (68%; 2 had an unknown primary) who went on to completion radiation at 67 to 72 Gy. After induction chemoradiation 21 patients with N1-3 nodes had neck dissection; 6 (31%) had positive nodes. Twelve patients had residual cancer at the primary site at time of rebiopsy: mandible, 4; maxilla, 1; base of tongue, 2; larynx, 4; floor of mouth, 1; and nasal cavity, 1. All were resected with function-preserving reconstruction. At median follow-up of >12 months, progression-free and overall survivals were 71% and 83%, respectively. conclusion Preoperative treatment with paclitaxel, carboplatin, and radiation is associated with high CR at the primary site and a high level of organ preservation or functional restoration if ablation is done.
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- 1997
237. Evolution of pancreatectomy with en bloc venous resection for pancreatic cancer in Italy. Retrospective cohort study on 425 cases in 10 pancreatic referral units.
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Nigri, Giuseppe, Petrucciani, Niccolò, Pinna, Antonio Daniele, Ravaioli, Matteo, Jovine, Elio, Minni, Francesco, Grazi, Gian Luca, Chirletti, Piero, Balzano, Gianpaolo, Ferla, Fabio, De Carlis, Luciano, Tisone, Giuseppe, Napoli, Niccolò, Boggi, Ugo, and Ramacciato, Giovanni
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Introduction: The aim of this study is to analyze the evolution of pancreatectomy with venous resection in 10 referral Italian centers in the last 25 years.Methods: A multicenter database of 425 patients submitted to pancreatectomy with venous resection between 1991 and 2015 was retrospectively analyzed. Patients were classified in 5 periods: 1 (1991-1995); 2 (1996-2000); 3 (2001-2005); 4 (2006-2010); 5 (2011-2015). Indications and outcomes were compared according to the period of surgery.Results: Nineteen patients were operated in period 1, 28 in period 2, 91 in period 3, 140 in period 4, and 147 in period 5. Use of neoadjuvant therapy increased from 0% in period 1 and 2-12.1% in period 5. Postoperative complications ranged from 46.3% to 67.8%, and mortality from 5.3% to 9.2%. Median survival progressively increased, from 6 months in period 1-16 months in period 2, 24 months in period 3 and 4 and 35 months in period 5 (p = 0.004). Period, venous and nodal invasion were significant prognostic factors for survival.Conclusion: Management and outcomes of pancreatectomy with venous resection have evolved in the last 25 years in Italy. Improvement in patients' multidisciplinary management has lead to significant improvement of median survival. [ABSTRACT FROM AUTHOR]- Published
- 2018
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238. Correção fisiológica guiada da linha média superior após expansão rápida da maxila.
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Franzotti Sant'Anna, Eduardo, Coelho Lorenzoni, Diego, da Cunha, Amanda Carneiro, Tomé Barreto, Bruna Caroline, and Paula Nigri, Anna
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Copyright of Revista Clínica de Ortodontia Dental Press is the property of Dental Press International and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2018
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239. Simultaneous removal of strontium and refractory organic compounds from electrodialysis effluents by modified bovine bone char
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Nigri, Elbert M., Santos, André L.A., Mesquita, Patrícia L., Viana, Paulo R.M., and Rocha, Sônia D.F.
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The presence of residual organic compounds has been harmful to salts crystallization processes. In addition, elements like strontium can damage industrial systems due to incrustation formation. This paper aims at evaluating the simultaneous removal of refractory organic compounds and strontium from industrial reverse electrodialysis wastewater of an oil refinery by adsorption onto bone char, in its fresh and modified surface forms, which constitutes the innovation of this work. The removal of 41% of chemical oxygen demand (COD) was obtained at the equilibrium time of 4 h whereas Sr removal of 37% required 24 h. The kinetics model of pseudo-second order described appropriately the system for both, COD and Sr removals. The strontium removal by bone char was better described by the Freundlich isotherm. The maximum removal of COD (54%) was attained by sulfamic acid pre-treated bone char and the maximum removal of strontium (61%) was obtained using nitric acid treated bone char. Regarding the organics removal, the Redlich-Peterson model better described the systems for untreated bone char and aluminum hydroxide modified bone char, whereas the Freundlich model fitted to aluminum sulfate modified bone char results. A moderate improvement of the organic compounds removal by aluminum sulfate modified bone char (ALBC) compared to untreated bone char (UTBC) from 18.43 to 22.31mg/L was obtained, respectively, using a solid liquid ratio of 60 g bone char/L wastewater.
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- 2019
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240. Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer
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Goehrig, Delphine, Nigri, Jérémy, Samain, Rémi, Wu, Zhichong, Cappello, Paola, Gabiane, Gae¨lle, Zhang, Xinyi, Zhao, Yajie, Kim, In-San, Chanal, Marie, Curto, Roberta, Hervieu, Valerie, de La Fouchardière, Christelle, Novelli, Francesco, Milani, Pascale, Tomasini, Richard, Bousquet, Corinne, Bertolino, Philippe, and Hennino, Ana
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ObjectivePancreatic cancer is associated with an abundant stromal reaction leading to immune escape and tumour growth. This massive stroma drives the immune escape in the tumour. We aimed to study the impact of βig-h3 stromal protein in the modulation of the antitumoural immune response in pancreatic cancer.DesignWe performed studies with p48-Cre;KrasG12D, pdx1-Cre;KrasG12D;Ink4a/Arffl/fl, pdx1-Cre;KrasG12D; p53R172Hmice and tumour tissues from patients with pancreatic ductal adenocarcinoma (PDA). Some transgenic mice were given injections of anti-βig-h3, anti-CD8, anti-PD1 depleting antibodies. Tumour growth as well as modifications in the activation of local immune cells were analysed by flow cytometry, immunohistochemistry and immunofluorescence. Tissue stiffness was measured by atomic force microscopy.ResultsWe identified βig-h3 stromal-derived protein as a key actor of the immune paracrine interaction mechanism that drives pancreatic cancer. We found that βig-h3 is highly produced by cancer-associated fibroblasts in the stroma of human and mouse. This protein acts directly on tumour-specific CD8+T cells and F4/80 macrophages. Depleting βig-h3 in vivoreduced tumour growth by enhancing the number of activated CD8+T cell within the tumour and subsequent apoptotic tumour cells. Furthermore, we found that targeting βig-h3 in established lesions released the tissue tension and functionally reprogrammed F4/80 macrophages in the tumour microenvironment.ConclusionsOur data indicate that targeting stromal extracellular matrix protein βig-h3 improves the antitumoural response and consequently reduces tumour weight. Our findings present βig-h3 as a novel immunological target in pancreatic cancer.
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- 2019
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241. Per Proudhon
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Lampugnani-Nigri, Arrigo
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- 1970
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242. Normative values of the topological metrics of the structural connectome: A multi-site reproducibility study across the Italian Neuroscience network.
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Borrelli, Pasquale, Savini, Giovanni, Cavaliere, Carlo, Palesi, Fulvia, Grazia Bruzzone, Maria, Aquino, Domenico, Biagi, Laura, Bosco, Paolo, Carne, Irene, Ferraro, Stefania, Giulietti, Giovanni, Napolitano, Antonio, Nigri, Anna, Pavone, Luigi, Pirastru, Alice, Redolfi, Alberto, Tagliavini, Fabrizio, Tosetti, Michela, Salvatore, Marco, and Gandini Wheeler-Kingshott, Claudia A.M.
- Abstract
• Graph-based metrics represent specific topological properties of brain connections. • Multi-site data are essential for evaluating the metrics' reliability. • The results provide useful insights for clinical reliability of topological metrics. The use of topological metrics to derive quantitative descriptors from structural connectomes is receiving increasing attention but deserves specific studies to investigate their reproducibility and variability in the clinical context. This work exploits the harmonization of diffusion-weighted acquisition for neuroimaging data performed by the Italian Neuroscience and Neurorehabilitation Network initiative to obtain normative values of topological metrics and to investigate their reproducibility and variability across centers. Different topological metrics, at global and local level, were calculated on multishell diffusion-weighted data acquired at high-field (e.g. 3 T) Magnetic Resonance Imaging scanners in 13 different centers, following the harmonization of the acquisition protocol, on young and healthy adults. A "traveling brains" dataset acquired on a subgroup of subjects at 3 different centers was also analyzed as reference data. All data were processed following a common processing pipeline that includes data pre-processing, tractography, generation of structural connectomes and calculation of graph-based metrics. The results were evaluated both with statistical analysis of variability and consistency among sites with the traveling brains range. In addition, inter-site reproducibility was assessed in terms of intra-class correlation variability. The results show an inter-center and inter-subject variability of <10%, except for "clustering coefficient" (variability of 30%). Statistical analysis identifies significant differences among sites, as expected given the wide range of scanners' hardware. The results show low variability of connectivity topological metrics across sites running a harmonised protocol. [ABSTRACT FROM AUTHOR]
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- 2023
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243. Quality assessment, variability and reproducibility of anatomical measurements derived from T1-weighted brain imaging: The RIN–Neuroimaging Network case study.
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Bosco, Paolo, Lancione, Marta, Retico, Alessandra, Nigri, Anna, Aquino, Domenico, Baglio, Francesca, Carne, Irene, Ferraro, Stefania, Giulietti, Giovanni, Napolitano, Antonio, Palesi, Fulvia, Pavone, Luigi, Savini, Giovanni, Tagliavini, Fabrizio, Bruzzone, Maria Grazia, Gandini Wheeler-Kingshott, Claudia A.M., Tosetti, Michela, and Biagi, Laura
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• Reproducibility of harmonized T1-weighted protocol at 3 T was tested in a multicentric study. • The study measured a global variability that ranges from 11% to 19% for subcortical volumes. • Moreover, we measured a global variability that ranges from 3% to 10% for cortical thicknesses. • The Bland-Altman analysis on traveling brain measures did not detect systematic scanner biases. • SVM can classify the scanner vendor from brain measures with an accuracy = 0.60 ± 0.14 (chance 0.33). Initiatives for the collection of harmonized MRI datasets are growing continuously, opening questions on the reliability of results obtained in multi-site contexts. Here we present the assessment of the brain anatomical variability of MRI-derived measurements obtained from T1-weighted images, acquired according to the Standard Operating Procedures, promoted by the RIN-Neuroimaging Network. A multicentric dataset composed of 77 brain T1w acquisitions of young healthy volunteers (mean age = 29.7 ± 5.0 years), collected in 15 sites with MRI scanners of three different vendors, was considered. Parallelly, a dataset of 7 "traveling" subjects, each undergoing three acquisitions with scanners from different vendors, was also used. Intra-site, intra-vendor, and inter-site variabilities were evaluated in terms of the percentage standard deviation of volumetric and cortical thickness measures. Image quality metrics such as contrast-to-noise and signal-to-noise ratio in gray and white matter were also assessed for all sites and vendors. The results showed a measured global variability that ranges from 11% to 19% for subcortical volumes and from 3% to 10% for cortical thicknesses. Univariate distributions of the normalized volumes of subcortical regions, as well as the distributions of the thickness of cortical parcels appeared to be significantly different among sites in 8 subcortical (out of 17) and 21 cortical (out of 68) regions of i nterest in the multicentric study. The Bland-Altman analysis on "traveling" brain measurements did not detect systematic scanner biases even though a multivariate classification approach was able to classify the scanner vendor from brain measures with an accuracy of 0.60 ± 0.14 (chance level 0.33). [ABSTRACT FROM AUTHOR]
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- 2023
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244. Selective organ preservation in operable locally advanced head and neck squamous cell carcinomas guided by primary site restaging biopsy: long-term results of two sequential brown university oncology group chemoradiotherapy studies
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Michael R. DiSiena, Ritesh Rathore, Prakash Chougule, K. Radie-Keane, Robert G. McRae, P. Nigri, Neal Ready, R. James Koness, and Harold J. Wanebo
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Oncology ,Adult ,Male ,medicine.medical_specialty ,Paclitaxel ,medicine.medical_treatment ,Biopsy ,Locally advanced ,Carboplatin ,chemistry.chemical_compound ,Surgical oncology ,Internal medicine ,Antineoplastic Combined Chemotherapy Protocols ,medicine ,Humans ,Aged ,Neoplasm Staging ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Remission Induction ,Neck dissection ,Organ Preservation ,Middle Aged ,Combined Modality Therapy ,Radiation therapy ,Survival Rate ,Treatment Outcome ,chemistry ,Gamma Rays ,Head and Neck Neoplasms ,Lymphatic Metastasis ,Carcinoma, Squamous Cell ,Neck Dissection ,Surgery ,Female ,Neoplasm Recurrence, Local ,business ,Chemoradiotherapy ,Follow-Up Studies - Abstract
The long-term outcomes of selective organ preservation in operable, locally advanced head and neck cancers in two sequential chemoradiotherapy (CRT) protocols (HN-53, HN-67) are reported. A total of 65 patients were treated with CRT consisting of carboplatin (AUC = 1/week) and paclitaxel (60 or 40 mg/m2/week) with radiation (1.8 Gy/day). After 5 weeks of CRT, if primary site biopsies were pathologically negative, then completion CRT to 67–72 Gy was done with neck dissection in node-positive cases. Alternatively, a positive rebiopsy required primary site resection and neck dissection followed by radiotherapy boost as deemed necessary. Pathologic complete responses occurred in 71% patients who then completed CRT; the remaining 29% patients underwent primary site surgery. The 5-year and median overall survival were 47% and 57 months with no statistically significant differences between the two groups. Overall long-term failure rates were: 6% local, 6% regional, and 32% distant. This strategy of selective organ preservation was effective in 71% patients with CRT, whereas salvage surgery was required in the remainder. Long-term survival was equivalent in both treatment groups.
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- 2010
245. Solitary Fibrous Tumor of the Buccal Space: Treatment with Percutaneous Cryoablation
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Damian E. Dupuy, L.M. Davis, P. Nigri, and Todd C Schirmang
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Thorax ,Solitary fibrous tumor ,Percutaneous ,medicine.medical_treatment ,Neoplasms, Fibrous Tissue ,Dermatologic Surgical Procedures ,Radiography, Interventional ,Cryosurgery ,stomatognathic system ,medicine ,otorhinolaryngologic diseases ,Humans ,Radiology, Nuclear Medicine and imaging ,Head & Neck ,business.industry ,Cryoablation ,Anatomy ,Cheek ,Middle Aged ,medicine.disease ,stomatognathic diseases ,medicine.anatomical_structure ,Paranasal sinuses ,Treatment Outcome ,Surgery, Computer-Assisted ,Abdomen ,Female ,Neurology (clinical) ,Buccal space ,Facial Neoplasms ,business ,Tomography, X-Ray Computed - Abstract
SUMMARY: Solitary fibrous tumors are rare spindle cell neoplasms that typically occur in the thorax but have been described in various locations within the abdomen and head and neck region. The most common extrapleural site is the oral cavity, but these tumors have been also described in the orbit, nasopharynx, paranasal sinuses, salivary glands, and larynx.(1–3) We describe a case of a solitary fibrous tumor of the buccal space successfully treated with percutaneous CT-guided cryoablation.
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- 2007
246. Early laryngeal inhalation injury and its correlation with late sequelae
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P. Nigri, Charles M. Ruhl, Urmen Desai, and Tulio A. Valdez
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Larynx ,Adult ,Lung Diseases ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Video Recording ,Laryngeal Diseases ,Bronchoscopy ,Swallowing ,medicine ,Intubation ,Humans ,Prospective Studies ,Stroboscopy ,Hoarseness ,medicine.diagnostic_test ,Inhalation ,business.industry ,Sequela ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Otorhinolaryngology ,Anesthesia ,Breathing ,Female ,business ,Deglutition Disorders ,Total body surface area ,Burns, Inhalation - Abstract
Objective: Inhalation injury can permanently alter normal laryngeal function. The aim of this study was to examine the early changes in voice, swallowing, and breathing in laryngeal inhalation injuries. Study Design: This was a prospective analysis of nine patients with inhalation injuries at a tertiary care institution. Methods: Laryngeal function of patients admitted for inhalation injury requiring intubation was documented using videostroboscopy and swallowing evaluation by the speech pathology service. Bronchoscopy was used to classify the degree of inhalation injury. Association among total body surface area, facial burns, severity of laryngotracheal injuries, and loss of function was attempted. Results: All three patients with severe tracheal inhalation injury presented persistent hoarseness at 1-year follow up with abnormal videostroboscopy findings. No association was found between inhalation injury and total body surface area burned. None of the patients in this series presented permanent swallowing dysfunction. Conclusion: The otolaryngologist plays an important role in the initial and long-term management of inhalation injuries. Inhalation injuries should be managed in a multidisciplinary fashion. There may be a correlation between the degree of tracheal injury and laryngeal injury and hoarseness.
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- 2006
247. População de protozoários ruminais em novilhos zebuínos alimentados com ou sem volumoso.
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Nigri, A. C. A., Ribeiro, I. C. O., Vieira, E. A., Silva, M. L. F., Virgínio-Júnior, G. F., Abrão, F. O., Geraseev, L. C., and Duarte, E. R.
- Abstract
This study aimed to quantify and identify the profile of the rumen protozoa population of beef steers fed with or without roughage. Nellore crossbred steers raised in extensive system on lignified tropical pastures with mineral supplementation and steers confined for 60 days only receiving pelletized concentrate and whole corn kernels were evaluated. After slaughter, rumen fluid was collected and one ml aliquots were diluted in nine ml formaldehyde solution at 10%. The counts of small, medium and large protozoa were held in Sedgewick Rafter chambers and identification of genus was possible after staining lugol and optical microscope with a 40X objective. The concentration of rumen protozoa positively correlated with pH ruminal. Cattle fed without roughage had significantly lower rumen protozoa population (P<0.05). Animals fed roughage had higher occurrence of Dasytrichia genus, Charonina, Entodinum, Diplodinium, Ostracodinium and Epidinium while those fed without bulk, the Buetschilia, Isotricha, Eodinium, Polyplastron, Elyplastron, Metadinium and Enoploplastron were the most frequent genus. [ABSTRACT FROM AUTHOR]
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- 2017
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248. Avaliação da morfologia interna de terceiros molares usando quatro métodos diferentes.
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de MATOS, Humberto Ramah Menezes, Parente LEITE, Suyane, Noronha NIGRI, Flavia Maria, Belmino MASTROIANNI, Luanni, and ANGELIM-DIAS, Aldo
- Abstract
Copyright of Dental Press Endodontics is the property of Dental Press International and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2017
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249. Rumen protozoa of different ages of beef cattle raised in tropical pastures during the dry season
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Duarte, Eduardo Robson, Abrão, Flávia Oliveira, Oliveira Ribeiro, Izabella Carolina, Vieira, Edvaldo Alves, Nigri, Ana Carolina, Silva, Kellerson Luiz, Virgínio Júnior, Gercino Ferreira, Prates Barreto, Silene Maria, and Geraseev, Luciana Castro
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ABSTRACTThe purpose of this study was to quantify, identify and compare the protozoa populations in the rumen of different ages of beef cattle raised in tropical pastures during the dry season. We sampled the ruminal fluid of 36 steers, 34 cows and 30 calves, all crossbred Nelore. The ruminal fluid was diluted in 10% formaldehyde solution and decimal dilutions were prepared in saline solution to quantify small, medium and large protozoa in Sedgewick Rafter chamber. A total of 135,800 protozoa were evaluated in an optical microscope using Lugol’s iodine coloration and the genera were classified according to the morphological characteristics. Total protozoa populations were significantly lower in calf samples. The average of small protozoa population was higher than that of other protozoa groups while the large ciliate population was lower. Protozoa belonging to 17 different genera were identified, showing diversity in this ecosystem. Charoninaspp. was the most frequent for both bovine groups. Entodiniumspp. was more prevalent in adult cattle and while Buetschiliaspp. was more prevalent in calves. In this study, a considerable population of ruminal ciliates presenting high diversity was observed in cattle raised on tropical lignified pastures and their genus profile varied according to the ages of the animals.
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- 2018
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250. Preoperative paclitaxel, carboplatin, and radiation therapy in advanced head and neck cancer (stage III and IV)
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H J, Wanebo, P, Chougule, N, Ready, R J, Koness, W, Akerley, R, McRae, P, Nigri, L, Leone, B, Webber, and H, Safran
- Subjects
Adult ,Aged, 80 and over ,Male ,Paclitaxel ,Middle Aged ,Combined Modality Therapy ,Survival Analysis ,Carboplatin ,Postoperative Complications ,Treatment Outcome ,Head and Neck Neoplasms ,Antineoplastic Combined Chemotherapy Protocols ,Preoperative Care ,Humans ,Female ,Prospective Studies ,Aged ,Neoplasm Staging - Abstract
Preoperative chemotherapy and chemoradiation protocols are generally associated with high clinical response rates but limited pathologic responses for large primary tumors. We have initiated a prospective phase II study of weekly paclitaxel and carboplatin plus concurrent, fractionated external-beam radiation, followed by organ-preserving or function-restorative surgery (when applicable to maximize locoregional tumor control). Operable patients staged by triple endoscopy received a percutaneous gastrostomy and vigorous dental and nutritional support during therapy. Paclitaxel 60 mg/m2 and carboplatin at an area under the concentration-time curve of 1 were administered weekly with radiation therapy 45 Gy, with repeat biopsy of the primary site at 5 weeks. Patients with a positive biopsy had definitive surgery within 4 to 5 weeks. Patients with a negative biopsy received 3 additional weeks of radiation therapy, to a total dose of 72 Gy plus paclitaxel and carboplatin. Forty-three patients were enrolled, including 33 men and 10 women ranging in age from 37 to 81 years. Fourteen patients had stage III disease, 19 patients had stage IVA disease, and 10 patients had stage IVB disease. Sites of disease included the floor of the mouth (n = 8), tongue (n = 8), oropharynx (n = 5), hypopharynx (n = 4), larynx (n = 12), palate-tonsil (n = 2), unknown primary (n = 3), and nasal cavity (n = 1). Of 38 patients evaluable for primary response (two patients had unknown primary tumor, two patients failed to complete the chemoradiation protocol, and one patient was evaluable for toxicity only), 18 patients had a complete clinical response and 20 patients had a partial response; the overall clinical response rate was 100%. A pathologic clinical response at the primary site occurred in 25 of these 38 patients (66%), who subsequently received completion radiation (67 to 72 Gy). After induction chemoradiation, 36 patients with N1-N3 nodes had neck dissection; seven had positive nodes (19%). Fourteen patients had residual cancer at the primary site at the time of the repeat biopsy. Sites of the lesions were the floor of the mouth/mandible (n = 4), nasal cavity/maxilla (n = 2), base of tongue (n = 2), and larynx (n = 6). All were resected with function-preserving reconstruction (two patients required total laryngectomy and one patient refused surgery). At a median follow-up of more than 16 months, progression-free and overall survival rates were 64% and 68%, respectively. Preoperative paclitaxel, carboplatin, and radiation was associated with a high clinical response rate at the primary site and a high level of organ preservation or functional restoration, if ablation was performed.
- Published
- 1999
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