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671 results on '"Mortensen, Erik L."'

207. The adaptation of a Danish version of the Pain Self- Efficacy Questionnaire: reliability and construct validity in a population of patients with fibromyalgia in Denmark.

Author

Rasmussen, Marianne U., Rydahl‐Hansen, Susan, Amris, Kirstine, Danneskiold Samsøe, Bente, and Mortensen, Erik L.

Subjects
PSYCHOLOGICAL adaptation, CHRONIC pain, STATISTICAL correlation, TEST validity, EXPERIMENTAL design, FACTOR analysis, FIBROMYALGIA, FOCUS groups, RESEARCH methodology, QUESTIONNAIRES, REHABILITATION centers, RESEARCH evaluation, RESEARCH funding, SCALE analysis (Psychology), SELF-efficacy, SELF-evaluation, STATISTICS, T-test (Statistics), DATA analysis, ACTIVITIES of daily living, SOCIOECONOMIC factors, STATISTICAL reliability, MULTITRAIT multimethod techniques, RESEARCH methodology evaluation, DESCRIPTIVE statistics, MANN Whitney U Test, INTRACLASS correlation
Abstract

The aim of this study was to translate, culturally adapt and evaluate the psychometric properties of the Pain Self- Efficacy Questionnaire ( PSEQ) in a population of patients with fibromyalgia in Denmark. The study sample included 102 patients diagnosed with fibromyalgia referred to a specialist clinic. The PSEQ was translated and adapted to a Danish setting using a standard stepw-ise forward-backward translation procedure, followed by initial testing and focus group interview. Reliability was examined by analysing internal consistency and test-retest agreement. Construct validity was exami-ned by investigating dimensionality, targeting, local independence, category functioning and differential item functioning ( DIF). Reliability was high: Cronbach's alpha 0.88, test-retest correlation 0.93, intraclass correlation coefficient ( ICC) 0.89 and item-total correlations 0.44-0.70. Factor analyses and item response ( IRT) models indicated unidimensionality, and the PSEQ- DK was well targeted to the sample. High interitem correlation was observed between two items, indicating local dependence, and item misfit and DIF were observed for a few items. However, the overall fit of the scale to a single-factor model and IRT models supported acceptable construct validity. The PSEQ- DK showed acceptable psychometric properties and can therefore represent a reliable and valid measure for evaluating self-efficacy in patients with fibromyalgia in Denmark. [ABSTRACT FROM AUTHOR]

Published
2016
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208. Neonatal levels of cytokines and risk of autism spectrum disorders: An exploratory register-based historic birth cohort study utilizing the Danish Newborn Screening Biobank

Author

Abdallah, Morsi W., primary, Larsen, Nanna, additional, Mortensen, Erik L., additional, Atladóttir, Hjördis Ó., additional, Nørgaard-Pedersen, Bent, additional, Bonefeld-Jørgensen, Eva Cecilie, additional, Grove, Jakob, additional, and Hougaard, David M., additional

Published
2012
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209. Early weaning and hospitalization with alcohol-related diagnoses in adult life

Author

Sørensen, Holger J., Mortensen, Erik L., Reinisch, June M., Mednick, Sarnoff A., Sørensen, Holger J., Mortensen, Erik L., Reinisch, June M., and Mednick, Sarnoff A.

Abstract

Objective: This study attempted to determine whether lack of breast-feeding or a short duration of breast-feeding during infancy is associated with an elevated risk of hospitalization with alcohol-related diagnoses in adult life. Method: The study was a prospective longitudinal birth cohort design conducted in a sample of 6,562 men and women, all of whom were born in Copenhagen, Denmark, between October 1959 and December 1961. The sample was divided into two categories based on duration of breast-feeding, as assessed by a physician interview with mothers at a 1-year examination. Psychiatric hospitaliza-tions with alcohol-related diagnoses ac-cording to ICD-8 or ICD-10 were identified in the Danish Psychiatric Central Register in 1999. Nine potential confounders were included as covariates: gender of the cohort member, maternal age, parental social status, maternal prenatal smoking, unwanted pregnancy, maternal and paternal psychiatric hospitalization with alcohol-related diagnosis, and maternal and paternal psychiatric hospitalization with other diagnosis. Results: Alcohol-related diagnoses were more frequent in men, but the results were comparable for men and women. The adjusted predictive effect of early weaning was 1.47. Elevated relative risks were also associated with maternal smok-ing during pregnancy (1.52) and un-wanted pregnancy status (1.59). Other in-dependent predictors were male gender, maternal psychiatric hospitalization with alcohol-related diagnosis, and low parental social status. Conclusions: Independent of a number of other risk factors for alcoholism, a significant association between early weaning and elevated risk of hospitalization with alcohol-related diagnoses was observed.

Published
2006

211. Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults.

Author

Demnitz, Naiara, Gates, Anne T., Mortensen, Erik L., Garde, Ellen, Wimmelmann, Cathrine L., Siebner, Hartwig R., Kjaer, Michael, and Boraxbekk, Carl‐Johan

Subjects
*OLDER people, *MOTOR cortex, *PHYSICAL mobility, *VOXEL-based morphometry, *STRENGTH training
Abstract

Understanding individual variability in response to physical activity is key to developing more effective and personalised interventions for healthy ageing. Here, we aimed to unpack individual differences by using longitudinal data from a randomised‐controlled trial of a 12‐month muscle strengthening intervention in older adults. Physical function of the lower extremities was collected from 247 participants (66.3 ± 2.5 years) at four time‐points. At baseline and at year 4, participants underwent 3 T MRI brain scans. K‐means longitudinal clustering was used to identify patterns of change in chair stand performance over 4 years, and voxel‐based morphometry was applied to map structural grey matter volume at baseline and year 4. Results identified three groups showing trajectories of poor (33.6%), mid (40.1%), and high (26.3%) performance. Baseline physical function, sex, and depressive symptoms significantly differed between trajectory groups. High performers showed greater grey matter volume in the motor cerebellum compared to the poor performers. After accounting for baseline chair stand performance, participants were re‐assigned to one of four trajectory‐based groups: moderate improvers (38.9%), maintainers (38.5%), improvers (13%), and decliners (9.7%). Clusters of significant grey matter differences were observed between improvers and decliners in the right supplementary motor area. Trajectory‐based group assignments were unrelated to the intervention arms of the study. In conclusion, patterns of change in chair stand performance were associated with greater grey matter volumes in cerebellar and cortical motor regions. Our findings emphasise that how you start matters, as baseline chair stand performance was associated with cerebellar volume 4 years later. [ABSTRACT FROM AUTHOR]

Published
2023
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216. Premorbid multivariate markers of neurodevelopmental instability in the prediction of adult schizophrenia-spectrum disorder: a high-risk prospective investigation

Author

Golembo-Smith, Shana, primary, Schiffman, Jason, additional, Kline, Emily, additional, Sørensen, Holger J., additional, Mortensen, Erik L., additional, Stapleton, Laura, additional, Hayashi, Kentaro, additional, Michelsen, Niels M., additional, Ekstrøm, Morten, additional, and Mednick, Sarnoff, additional

Published
2012
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243. The personality trait openness is related to cerebral 5-HTT levels

Author

Kalbitzer, Jan, primary, Frokjaer, Vibe G., additional, Erritzoe, David, additional, Svarer, Claus, additional, Cumming, Paul, additional, Nielsen, Finn Å., additional, Hashemi, Sayed H., additional, Baaré, William F.C., additional, Madsen, Jacob, additional, Hasselbalch, Steen G., additional, Kringelbach, Morten L., additional, Mortensen, Erik L., additional, and Knudsen, Gitte M., additional

Published
2009
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247. Frontolimbic Serotonin 2A Receptor Binding in Healthy Subjects Is Associated with Personality Risk Factors for Affective Disorder

Author

Frokjaer, Vibe G., primary, Mortensen, Erik L., additional, Nielsen, Finn Å., additional, Haugbol, Steven, additional, Pinborg, Lars H., additional, Adams, Karen H., additional, Svarer, Claus, additional, Hasselbalch, Steen G., additional, Holm, Soeren, additional, Paulson, Olaf B., additional, and Knudsen, Gitte M., additional

Published
2008
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248. The psychological profile of bariatric patients with and without type 2 diabetes: baseline results of the longitudinal GASMITO-PSYC study.

Author

Wimmelmann, Cathrine L., Smith, Evelyn, Lund, Michael T., Hansen, Merethe, Dela, Flemming, and Mortensen, Erik L.

Abstract

Background Some bariatric patients are referred for surgery with a diagnosis of type 2 diabetes while others are referred without co-morbid diabetes, but psychological differences between patients with and without type 2 diabetes undergoing bariatric surgery have not yet been investigated. The objective of this study was to present the baseline results of the longitudinal GASMITO-PSYC study, and to evaluate the psychological differences between bariatric patients with and without type 2 diabetes. Methods A total of 129 Roux-en- Y gastric bypass patients were recruited from the bariatric clinic at a hospital in the suburban Copenhagen area. Participants answered questionnaires concerning personality, mental symptoms, health-related quality of life (HRQOL), body image, lifestyle, and physical health including diabetes status on average 11 weeks before surgery. Questionnaires were either sent to the participant’s home address or administered at the University of Copenhagen. Results Patients with type 2 diabetes scored higher on ‘physical function’ ( P = .001), ‘physical role’ ( P = .014), ‘physical pain’ ( P = .021), and ‘vitality’ ( P = .007) than nondiabetic patients after controlling for sex and age. The total study sample differed significantly from Danish test norms reporting higher neuroticism ( P = .000), more mental symptoms ( P = .000), lower HRQOL ( P = .000), and less positive weight-related body image ( P = .000). Conclusion Patients with type 2 diabetes had better physical HRQOL than nondiabetic patients. This study highlights the importance of investigating whether these differences affect surgical outcomes. [ABSTRACT FROM AUTHOR]

Published
2015
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249. The impact of virtual admission on self-efficacy in patients with chronic obstructive pulmonary disease -- a randomised clinical trial.

Author

Emme, Christina, Mortensen, Erik L, Rydahl‐Hansen, Susan, Østergaard, Birte, Svarre Jakobsen, Anna, Schou, Lone, and Phanareth, Klaus

Subjects
*DISEASE exacerbation, *HOME care services, *REPEATED measures design, *PATIENTS, *SELF-efficacy, *T-test (Statistics), *HOSPITAL admission & discharge, *STATISTICAL sampling, *INTERVIEWING, *SAMPLE size (Statistics), *RANDOMIZED controlled trials, *DISCHARGE planning, *DESCRIPTIVE statistics, *TELEMEDICINE, *OBSTRUCTIVE lung diseases, *CONFIDENCE intervals, *PATIENTS' attitudes
Abstract

Aims and objectives. To investigate how virtual admission during acute exacerbation influences self-efficacy in patients with chronic obstructive pulmonary disease, compared with conventional hospital admission. Background. Telemedicine solutions have been highlighted as a possible way to increase self-efficacy in patients with chronic diseases, such as chronic obstructive pulmonary disease. However, little is known about how telemedicine-based virtual admission as a replacement of hospital admission during acute exacerbation affects chronic obstructive pulmonary disease patients' self-efficacy. Design. This study was a nonblinded, randomised clinical multicentre trial. The study was a substudy to The Virtual Hospital, investigating the feasibility and safety of telemedicine-based treatment at home for patients with acute exacerbation of chronic obstructive pulmonary disease. Methods. Participants were consecutively randomised to virtual admission or conventional hospital admission. Data from 50 patients were analysed. Self-efficacy was assessed at baseline, three days after discharge, and also six weeks and three months after discharge, using the Danish version of 'The chronic obstructive pulmonary disease self-efficacy scale'. Results. Intergroup comparison showed no significant differences between the two groups at baseline, three days after discharge, six weeks after discharge or three months after discharge. Furthermore, intragroup comparison did not reveal significant differences in the chronic obstructive pulmonary disease self-efficacy scale mean sum score within the two groups. Conclusions. The results of the study suggest that there is no difference between self-efficacy in chronic obstructive pulmonary disease patients undergoing virtual admission, compared with conventional hospital admission. However, the anticipated sample size could not be reached, which prompts caution regarding interpretation of the findings. Relevance to clinical practice. This study provides new insight into how virtual admission affects chronic obstructive pulmonary disease patients' self-efficacy. Clinicians should consider the timing, duration and the content in the design of telemedical interventions directed at improving chronic obstructive pulmonary disease patients' self-efficacy, as telemedicine solutions alone may not be sufficient to enhance self-efficacy. [ABSTRACT FROM AUTHOR]

Published
2014
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